tetradecanoylphorbol acetate has been researched along with Leukemia in 275 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 103 (37.45) | 18.7374 |
| 1990's | 112 (40.73) | 18.2507 |
| 2000's | 38 (13.82) | 29.6817 |
| 2010's | 18 (6.55) | 24.3611 |
| 2020's | 4 (1.45) | 2.80 |
| Authors | Studies |
|---|---|
| Huang, HL; Huang, RL; Huang, YL; Lin, TW | 1 |
| Bosnjak, M; Ciric, D; Harhaji-Trajkovic, L; Jovanovic, M; Mandic, M; Misirkic Marjanovic, M; Perovic, V; Ristic, B; Trajkovic, V; Vucicevic, L | 1 |
| Ciepiela, O; Demkow, U; Głodkowska-Mrówka, E; Mrówka, P; Ostafin, M; Pruchniak, M; Ulińska, E; Wachowska, M | 1 |
| Akita, H; Asuka, T; Eguchi, H; Ito, N; Kamada, Y; Miyoshi, E; Mori, S; Morii, E; Morishita, K; Motooka, K; Nojima, S; Otsu, R; Sakata, N; Takamatsu, S; Yamada, M | 1 |
| Ben-David, Y; Gajendran, B; Hao, X; Liu, W; Sample, KM; Varier, KM; Wang, C; Yao, Y; Zacksenhaus, E | 1 |
| Hartmann, JX; Keating, P; Marí, F; Padilla, A | 1 |
| Ngan, AHW; Pang, X; Peng, Y; Ruiz-Ortega, LI; Tang, B; Tian, Y; Wang, K; Xue, Y; Zhang, Y | 1 |
| Fukushima, S; Furutani, R; Hazama, S; Hirano, T; Hirobe, C; Hu, XM; Imai, M; Kamoi, S; Kikuchi, H; Nishimura, Y; Ohyama, K; Seno, M; Takagi, N; Toyoda, H; Yuan, B | 1 |
| Jankowski, H; Ji, X; Stanberry, L | 1 |
| Andrews, IP; Blumberg, PM; Kedei, N; Ketcham, JM; Krische, MJ; Lewin, NE; Peach, ML | 1 |
| Bak, Y; Hong, J; Kang, JW; Kim, MS; Lee, DH; Lee, HG; Park, YS; Yang, Y; Yoon, DY | 1 |
| Kim, Y; Kim, YI; Lee, JH; Lee, KW; Park, SW; Woo, HJ; Yoon, YK | 1 |
| Brimson, S; Parnsamut, C | 1 |
| Chen, S; Li, Y; Wang, W; Yang, L; Yu, X; Zeng, C | 1 |
| Brix, L; Chen, GL; Hahn, TE; Maguire, O; McCarthy, PL; Minderman, H; Wallace, PK | 1 |
| Bunaciu, RP; Mao, CD; Tang, T | 1 |
| Cen, J; Chen, Z; Gu, M; Liu, D; Qi, X | 1 |
| Ledford, H | 1 |
| Hyun, YM; Kim, M; Knauf, PA; Law, FY; Lefort, CT; Schultz, JB; Waugh, RE | 1 |
| Hajighasemi, F; Hajighasemi, S | 1 |
| Allgayer, H; Leupold, JH; Mudduluru, G; Stroebel, P | 1 |
| Aida, J; Banba, A; Hasegawa, Y; Higuchi, S; Hirabayashi, Y; Ichikawa, S; Kikuchi, A; Nagano-Ito, M; Saga, M; Shimizu, T | 1 |
| Hajighasemi, F | 1 |
| de Paula, CA; Jochum, M; Karow, M; Mayer, B; Nakahata, AM; Neth, P; Oliva, ML; Ries, C; Sampaio, MU | 1 |
| Braess, J; Holdenrieder, S; Kolligs, FT; Manukyan, D; Stieber, P | 1 |
| Gao, XM; Ge, FM; Li, XY; Liu, YH; Wang, WQ; Wang, Z | 1 |
| Kirsch, KH; Kumbrink, J | 1 |
| Hishita, T; Ichiyama, S; Miura, Y; Mizutani, C; Nishihara, T; Tohyama, K; Tohyama, Y; Uchiyama, T; Yamamura, H | 1 |
| Gerlo, S; Hooghe-Peters, EL; Kooijman, R; Vanden Berghe, W; Verdood, P | 1 |
| Kato, M; Kimura, H; Kobayashi, Y; Kozawa, K; Kuroiwa, M; Minakami, H; Morikawa, A; Oshima, S | 1 |
| Brewer, G; Huynh, Y; Lu, J; Sun, Y; Sutphen, K; Wilson, GM | 1 |
| Asano, H; Banno, Y; Hagiwara, K; Koda, M; Kojima, T; Murate, T; Nakade, Y; Nozawa, Y; Sobue, S; Suzuki, M; T-Koizumi, K; Takagi, A | 1 |
| Corazza, F; Harfi, I; Hayez, N; Lema-Kisoka, R; Sariban, E; Svoboda, M | 1 |
| Apáti, A; Brózik, A; Jánossy, J; Magócsi, M | 1 |
| Humeniuk-Polaczek, R; Marcinkowska, E | 1 |
| Chen, GQ; Chen, Z; Huang, Y; Li, D; Li, X; Peng, ZG; Shen, WZ; Sims, PJ; Wiedmer, T; Zhao, J; Zhao, KW; Zhao, Q; Zhou, Q | 1 |
| Ahmed, W; Dent, P; Grant, S; Rahmani, M | 1 |
| Blasius, R; Borde-Chiché, P; Delhalle, S; Dicato, M; Diederich, M; Duvoix, A; Morceau, F; Schnekenburger, M | 1 |
| Lindberg, SR; Olsson, A; Olsson, I; Persson, AM | 1 |
| Aplan, PD; Lin, YW; Slape, C; Zhang, Z | 1 |
| Aubery, M; Bernard, M; Braut-Boucher, F; Bringuier, A; Derappe, C; Feldmann, G; Foglietti, MJ; Plantin-Carrenard, E; Vadrot, N | 1 |
| Bauer, RA; Pores-Fernando, AT; Wurth, GA; Zweifach, A | 1 |
| Auberger, P; Belhacene, N; Cassuto, JP; Colosetti, P; Deckert, M; Defamie, V; Herrant, M; Hofman, P; Jacquel, A; Legros, L; Marchetti, S; Mari, B | 1 |
| Glesne, D; Huberman, E; Legnini, D; Maser, J; Vogt, S | 1 |
| Gabrilovac, J; Martin-Kleiner, I; Svoboda-Beusan, I | 1 |
| Magnusson, KE; Navakauskiene, R; Pivoriūnas, A; Savickiene, J; Treigyte, G; Tunaitis, V | 1 |
| Ballington, JR; Bowman, L; Ding, M; Feng, R; Lu, Y; Wang, SY | 1 |
| Toyoda, H; Uchide, N | 1 |
| Bertram, C; Hass, R; Schlegelberger, B; Skawran, B; Steinemann, D; von Neuhoff, N | 1 |
| Adolf, GR; Fischer, P; Haas, OA; Swetly, P | 1 |
| Bollum, FJ; Breviario, D; LeBien, TV; Sacchi, N; Trost, S | 1 |
| Massaro, F; Mulder, A; Schreuder-van Gelder, R; Tetteroo, PA; von dem Borne, AE | 1 |
| Imboden, J; Shoback, D; Stobo, J; Weiss, A | 1 |
| Shackelford, DA; Trowbridge, IS | 1 |
| Bornkamm, GW; Hudewentz, J; Zur Hausen, H | 1 |
| Kriegel, H; Schmahl, W; Senft, E | 1 |
| Broder, S; DiNapoli, AM; Pincus, SH; Schooley, WR | 1 |
| Mitsuma, T; Vogt, A; Yamamoto, N | 1 |
| Paietta, E | 1 |
| Stobo, JD; Weiss, A; Wiskocil, RL | 1 |
| Ikebuchi, H; Terao, T; Teshima, R | 1 |
| Bloomfield, CD; Brunning, R; Gajl-Peczalska, KJ; Gregg, SL; LeBien, TW; Sagawa, K | 1 |
| Koga, M; Srivastava, BI; Srivastava, P | 1 |
| Al-Katib, A; Koziner, B | 1 |
| Gralow, J; Miller, RA | 1 |
| Arya, SK; Gallo, RC; Wong-Staal, F | 1 |
| Kitagawa, S; Miura, Y; Ohta, M; Saito, M; Sakamoto, S; Suda, K; Takaku, F | 1 |
| Delia, D; Newman, RA | 1 |
| Honma, Y; Hozumi, M; Kasukabe, T; Nakazawa, S | 1 |
| Davies, C; Godal, T; Kvaløy, S; Lindmo, T; Wisløff, F | 1 |
| Ascensao, JL; Mickman, JK | 1 |
| Kadin, ME; Nasu, K; Sako, D; Su, IJ | 1 |
| Hiai, H; Kaneshima, H; Nishi, Y; Nishizuka, Y | 1 |
| Bloch, A; Minowada, J; Ozer, H; Sakagami, H; Takeda, K | 1 |
| Park, CH | 1 |
| Litcofsky, PB; Moore, MA; Ralph, P; Williams, N | 1 |
| Hashimoto, Y; Kimura, Y; Miura, Y; Ozawa, K; Takaku, F; Urabe, A | 1 |
| Abrahm, J; Cooper, RA; Lange, B; Levis, A; Meo, P; Pegoraro, L; Rovera, G | 1 |
| Arlin, Z; Clarkson, BD; Holland, JF; Koziner, B; Mendelsohn, N; Svet-Moldavskaya, IA; Svet-Moldavsky, GJ; Zinzar, SN | 1 |
| Hiragun, A; Ishimura, K; Mitsui, H | 1 |
| Dawson, G; Golomb, HM; Lockney, MW | 2 |
| Fukuda, M | 1 |
| Cabot, MC; Welsh, CJ | 1 |
| Avalos, BR; Bartynski, KJ; Burton, WG; Elder, PJ; Kotur, MS; Wilkie, NM | 1 |
| Barckow, P; Fiebeler, A; Graham, DK; Huhn, D; Neubauer, A; O'Bryan, JP; Schmidt, CA; Serke, S; Siegert, W; Snodgrass, HR | 1 |
| Heike, T; Jung, EY; Katamura, K; Mayumi, M; Ohshima, Y; Shintaku, N; Sumimoto, S | 1 |
| Garcia-Welsh, A; Laskin, DL; Laskin, JD; Molloy, CJ | 1 |
| Baker, J; Chao, NJ; Chen, Y; Fernandez, LP; Schlegel, PG | 1 |
| Davey, MW; Davey, RA; Kidman, AD; Marks, DC | 1 |
| Fujimoto, T; Tsurusawa, M | 1 |
| Hashimoto, Y; Iwasaki, S; Nishimura, K; Sasaki, K; Shibata, Y | 1 |
| Hamada, J; Hosokawa, M; Imamura, M; Kobayashi, M; Li, YQ; Okada, F; Shinobu, N; Takeichi, N | 1 |
| Bhatia, M; Kirkland, JB; Meckling-Gill, KA | 1 |
| Waxman, FJ; Yaskanin, DD | 1 |
| Lin, CH; Palma, JF; Solomon, WB | 1 |
| Chen, J; Cook, P; deVente, J; Fletcher, D; Garris, T; Hooker, J; Parker, P; Posekany, K; Qin, W; Ways, DK | 1 |
| Fey, MF; Koeffler, HP; Loetscher, P; Nagel, S; Niklaus, G; Schwaller, J; Tobler, A | 1 |
| Briggs, JA; Briggs, RC; Clark, J; Dessypris, EN; Dworkin, LL; Kao, WY | 1 |
| Hashimoto, Y; Iwasaki, S; Nishimura, K; Sasaki, K; Shibata, Y; Shichita, M | 1 |
| Dertinger, SD; Tometsko, AM; Torous, DK | 1 |
| Srivastava, A; Srivastava, BI; Srivastava, MD | 1 |
| DeJesus, A; Giovanella, BC; Kufe, D; Mendoza, JT; Pantazis, P; Rubin, E | 1 |
| Ishikawa, T; Ishizuka, H; Wright, CD | 1 |
| Conti, DJ; Freed, BM; Gallichio, MH; Geiselhart, L; Gruber, SA; Lempert, N | 1 |
| Lee, CW | 1 |
| Berkovic, D; Berkovic, K; Eibl, H; Fleer, EA; Unger, C | 1 |
| Furukawa, K; Shiku, H; Urano, T; Yamashiro, S | 1 |
| Henning-Chubb, C; Huberman, E; Tonetti, DA; Yamanishi, DT | 1 |
| Call, KM; Lindberg, C; Phelan, SA | 1 |
| Goto, M; Jikai, J; Konaka, Y; Ryo, R; Saigo, K; Sawada, H; Sawada, S; Sugano, W; Taniguchi, H; Yasunaga, M | 1 |
| Cho, KC; Kim, IS; Lee, SB | 1 |
| Chen, J; Cook, PP; Cooper, DR; Garris, TO; Hao, E; Parker, PJ; Qin, W; Usala, SJ; Ways, DK | 1 |
| Kanzaki, T; Morisaki, N; Saito, Y; Ueda, S; Yokote, K; Yoshida, S; Zenibayashi, M | 1 |
| Drexler, HG; Hu, ZB; Ma, W; Uphoff, CC | 1 |
| Berdel, WE; Fukuhara, T; Shoji, M; Vogler, WR; Winton, EF | 1 |
| Cannat, A; Cellier, MF; Chateau, MT; Marti, J; Taimi, M | 1 |
| Bruserud, O; Ehninger, G; Hamann, W; Patel, S; Pawelec, G; Schmidt, H | 1 |
| Cloyd, MW; Kawa, S; Smith, JS; Thompson, EB | 1 |
| Broggini, M; D'Incalci, M; Fabbri, S; Prontera, C | 1 |
| Furukawa, K; Shiku, H; Takayama, K; Yamashiro, S | 1 |
| Adra, CN; Caput, D; Guillemot, JC; Khagad, M; Lelias, JM; Lim, B; Wulf, GM | 1 |
| Bustelo, XR; Freire, M; Gómez-Márquez, J; Otero, A; Pichel, JG | 1 |
| Hannun, YA; Karolak, LA; Linardic, CM; Obeid, LM | 1 |
| Liuzzo, JP; Moscatelli, D | 1 |
| Chorváth, B; Hunáková, L; Klobusická, M; Sedlák, J; Sulíková, M | 1 |
| Franklin, CC; Kraft, AS | 1 |
| Alessio, M; De Monte, L; Gruarin, P; Scirea, A; Sitia, R; Tandon, NN | 1 |
| Dupont, B; Liu, XR; Mills, GB; Teng, JM | 1 |
| Asaka, M; Hansen, SR; Kunieda, Y; Kurosawa, M; Nakane, S; Okabe, M; Shoji, M; Tanaka, J | 1 |
| Kurosaki, T; Maruyama, S; Sada, K; Yamamoto, T; Yamamura, H; Yamanashi, Y | 1 |
| Tani, T; Virtanen, I; Ylänne, J | 1 |
| Challier, C; Drexler, HG; Janssen, JW; Uphoff, CC | 1 |
| Cardie, J; Dai, W; Greenberg, JM; Li, B; Means, RT; Ouyang, B; Pan, HQ | 1 |
| Hoshino, S; Inoue, S; Kanda, Y; Katada, T; Kishimoto, H; Kontani, K; Kukimonto, I | 1 |
| Andersson, AC; Botling, J; Cohen, M; Fan, W; Larsson, E; Nilsson, K; Oberg, F; Rigby, S; Venables, PJ | 1 |
| Bureau, JP; Caravano, R; Château, MT; Chiesa, J; Ginestier-Verne, C | 1 |
| Balasubramanyam, M; Gardner, JP | 1 |
| Sasaki, R | 1 |
| Antalis, TM; Costelloe, E; Donnan, K; Muddiman, J; Ogbourne, S | 1 |
| Drexler, HG; Graf, G; Quentmeier, H; Zaborski, M | 1 |
| Gronostajski, RM; Kulkarni, S | 1 |
| Bruni, P; Farnararo, M; Meacci, E; Vasta, V | 1 |
| Dubyak, GR; Kertesy, SB | 1 |
| Masuda, Y; Nakajo, S; Nakaya, K; Nakaya, M | 1 |
| Aiuchi, T; Masuda, Y; Nakajo, S; Nakaya, K; Ohizumi, H; Watabe, M; Yoda, M | 1 |
| Moreb, JS; Schweder, M | 1 |
| Dai, W; Lei, KY; Pike, JW; Wang, Y; Zhang, JJ | 1 |
| Macfarlane, DE; Manzel, L | 1 |
| Baz, A; Bureau, JP; Château, MT; Henry, L; Scherrer, K | 1 |
| Clifford, EE; Dalal, P; Dubyak, GR; Martin, KA; Thomas, R | 1 |
| Bomsztyk, K; Denis, GV; Florio, SK; Ostrowski, J; Suzuki, H | 1 |
| Baumeister, H; Grützkau, A; Henz, BM; Kögel, H; Krüger-Krasagakes, S; Lippert, U; Möller, A; Schwarz, C; Welker, P | 1 |
| Kiss, A; Rák, K; Schlammadinger, J; Sipka, S; Szabó, G; Szegedi, G; Tóth, G | 1 |
| Brandi, ML; Fiorelli, G; Franceschelli, F; Franchi, A; Frediani, U; Gori, F; Martineti, V; Serio, M; Tanini, A | 1 |
| Harmon, JM; Ramdas, J | 1 |
| Belinson, J; Morton, RE; Shen, Z; Xu, Y | 1 |
| Chylicki, K; Gullberg, U; Svedberg, H | 1 |
| Dent, P; Grant, S; Kramer, LB; Povirk, LF; Saunders, AM; Vrana, JA; Zhang, XF | 1 |
| Arnould, A; Bodger, M; Dy, M; Hermine, O; Machavoine, F; Mayeux, P; Pacilio, M; Schneider, E | 1 |
| Berry, DM; Meckling-Gill, KA | 1 |
| Garden, OA; Musk, P; Rich, IN; Worthington-White, D | 1 |
| Drexler, HG; Meyer, C; Steube, KG | 1 |
| Brentani, MM; Federico, MH; Folgueira, MA; Katayama, ML; Maistro, S; Roela, RA | 1 |
| Baek, S; Baek, W; Bang, O; Kim, J; Kim, JH; Kwon, TK; Lee, Y; Lee, YJ; Park, J; Suh, M; Suh, S | 1 |
| Dohi, K; Ishizaka, Y; Isumi, Y; Kangawa, K; Kubo, A; Matsuo, H; Minamino, N; Tomoda, Y | 1 |
| Bruey, JM; Corcos, L; Garrido, C; Leroy, I; Lizard, G; Miguet, C; Plenchette, S; Rébé, C; Solary, E; Sordet, O | 1 |
| Holian, O; Kakpakova, ES; Ktitorova, OV; Shtil, AA | 1 |
| Du, G; Huang, X; Li, G; Qiang, B; Shen, Y; Wang, J; Yin, B; Yuan, J; Zhou, Y | 1 |
| Cuvillier, O; Levade, T | 1 |
| Eastman, A; Ganju, N; Sporn, MB; Stadheim, TA; Suh, N | 1 |
| Bianchi, L; Cellai, C; Della Malva, N; Laurenzana, A; Paoletti, F; Vannucchi, AM | 1 |
| Castagna, M; Mishal, Z; Rochette-Egly, C; Rosenfeld, C | 1 |
| Loeb, LA; Reid, TM | 1 |
| Cockerell, GL; Jensen, WA; Wicks-Beard, BJ | 1 |
| Adler, V; Kraft, AS; Polotskaya, A; Wagner, F | 1 |
| Deguchi, K; Ito, M; Kobayashi, K; Kuno, T; Morita, K; Nagao, M; Nakano, T; Nishikawa, M; Shima, H; Tanaka, C | 1 |
| Drexler, HG; Gignac, SM; Grunicke, D; Pettit, GR; Pietsch, T; Steube, KG | 1 |
| Hamilton, SE; Hemphill, JE; Lavin, MF; Michael, J; Pettit, GR; Watters, DJ | 1 |
| Alliel, PM; Bonnet, F; Jollès, P; Maillet, P; Mitjavila, MT; Périn, JP | 1 |
| Harada, N; Koike, T; Morikawa, M; Yoshida, T | 1 |
| Chuang, LF; Chuang, RY; Israel, M; Kung, HF | 1 |
| Murgo, AJ; Sistare, FD | 1 |
| Arsura, M; Golay, J; Introna, M; Mantovani, A; Passerini, F | 1 |
| Kuo, JF; Woo, CF; Zheng, B | 1 |
| Cappuccini, F; Gatanaga, M; Gatanaga, T; Granger, GA; Hwang, CD; Yamamoto, RS | 1 |
| Altschuler, E; Chan, D; Hinds, M; Mayes, J; Zwelling, LA | 1 |
| Belvin, MP; Freedman, AS; Griffin, JD; Penta, AC; Spertini, O; Tedder, TF | 1 |
| Lipsky, PE; Minakuchi, R; Wacholtz, MC | 1 |
| Hara, J; Inoue, M; Ishihara, S; Koizumi, S; Kurahashi, H; Murayama, N; Okamura, J; Tawa, A; Toyoda, Y; Yumura-Yagi, K | 1 |
| Espinosa, R; Gill, HJ; Harden, A; LeBeau, MM; McCabe, NR; Patel, Y; Rowley, JD; Rubinelli, P; Smith, SD; Ziemin-van der Poel, S | 1 |
| Cotter, TG; Glynn, JM; Green, DR; Lennon, SV | 1 |
| Hsu, SM; Mehta, K; Sanduja, R; Sanduja, SK; Wu, KK; Xu, XM | 1 |
| Hamanaka, R; Kohno, K; Kuwano, M; Ono, M; Sato, Y; Seguchi, T | 1 |
| Konno, S; Wu, JM | 1 |
| Miyamoto, S; Wu, JM | 1 |
| Dasgupta, JD; Granja, C; Lin, LL; Relias, V; Yunis, EJ | 1 |
| Bellomo, R; Mingari, MC; Moretta, L; Pella, N; Poggi, A | 1 |
| Baxter, MA; Brown, G; Bunce, CM; Grafton, G; Sheppard, MC | 1 |
| Singh, N | 1 |
| Leung, S; Miyamoto, NG | 1 |
| Katoh, S; Matsuda, I; Matsumoto, R; Migita, M; Mita, S; Sonoda, E; Takatsu, K; Tominaga, A; Tsuchiya, H; Yamaguchi, N | 1 |
| Datta, R; Imamura, K; Kufe, DW; Sherman, ML; Stone, RM | 1 |
| Brunsing, D; Hensel, G; Krönke, M; Meichle, A; Schütze, S | 1 |
| Scholz, W | 1 |
| Altman, A; Isakov, N; McMahon, P | 1 |
| Fisher, TC; Gailani, D; Macfarlane, DE; Mills, DC | 1 |
| Dohmen, K; Gondo, H; Ishibashi, H; Kondo, H; Kudo, J; Niho, Y; Okamura, S; Shimamura, R | 1 |
| Fisher, PB; Grant, S | 1 |
| Borst, J; Klein, H; Melief, CJ; van Lier, RA; Van Mourik, P; Vroom, TM; Zeijlemaker, WP | 1 |
| Balk, SP; Kadin, ME; Su, IJ | 1 |
| Irino, S; Kubota, Y; Tanaka, T | 1 |
| Afanas'ev, BV; Balaian, LN; Ostrovskiĭ, AM; Prianishnikov, VA | 1 |
| Fujiwara, M; Nakajima, M; Narumiya, S; Okuma, M; Ushikubi, F; Yamamoto, M | 1 |
| Ali, H; Beaven, MA; Cunha-Melo, JR; Gonzaga, HM; Huang, FL; Huang, KP | 1 |
| Gavioli, R; Giuliani, AL; Spisani, S; Traniello, S | 1 |
| Folks, TM; Griffin, GE; Kunkel, S; Leung, K; Nabel, GJ | 1 |
| Gu, XB; Santorelli, AC; Sartorelli, AC; Xia, XJ; Yu, RK | 1 |
| Mekshenkov, MI; Nedospasov, SA; Seregina, TM; Turetskaya, RL | 1 |
| Frydecka, I; Harłozińska, A; Kuliczkowski, K; Noworolska, A; Sedek, K | 1 |
| Araki, N; Horiuchi, S; Morino, Y; Saitoh, M; Shiga, M; Takata, K | 1 |
| Fujii, M; Hinuma, Y; Nakamura, M; Ohtani, K; Sugamura, K | 1 |
| Ganser, A; Heil, G; Heimpel, H; Heit, W; Hoelzer, D; Kurrle, E; Raghavachar, A | 1 |
| Koubek, K; Lemez, P; Lojda, Z; Malasková, V | 1 |
| Brière, J; Le Bris, MJ; Le Calvez, G; Léglise, MC; Rivière, D; Sensebé, L | 1 |
| Chuang, LF; Chuang, RY; Israel, M; Zhao, FK | 1 |
| Deanin, GG; Feibig, ML; Oliver, JM; Pfeiffer, JR; Seagrave, JC | 1 |
| Carrel, S; Giuffrè, L; Isler, P; Mach, JP; Miescher, G; Salvi, S; Schreyer, M | 1 |
| Bjorndahl, JM; Fu, SM; Kao, HT; Sung, SS; Wang, CY | 1 |
| Metzger, H; White, KN | 1 |
| Fidelus, RK; Laughter, AH | 1 |
| Filli, S; Ioannides, CG; Papamichail, M; Petraki, H | 1 |
| Ashmun, RA; Beck, WT; Cirtain, MC; Mirro, J | 1 |
| Mazzone, A; Ricevuti, G; Rizzo, SC; Sacchi, S | 1 |
| Ganser, A; Heil, G; Heimpel, H; Heit, W; Hoelzer, D; Kurrle, E | 1 |
| Al-Katib, A; Hashimi, L; Koziner, B; Wang, CY | 1 |
| Bartram, CR; Böhm, T; Carbonell, F; Ganser, A; Heil, G; Hoelzer, D; Raghavachar, A | 1 |
| Allouche, M; Bentaboulet, M; Georgoulias, V; Jasmin, C; Tsapis, A | 1 |
| Amadori, S; Bottero, L; Mandelli, F; Mastroberardino, G; Mavilio, F; Pelosi, E; Peschle, C; Petrini, M; Sposi, NM; Testa, U | 1 |
| Kitagawa, S; Miura, Y; Ohta, M; Saito, M; Takaku, F | 1 |
| Kimura, N; Koga, Y; Mak, TW; Minowada, J | 1 |
| Bastin, B; Dupuis, G | 1 |
| Fu, SM; Jung, LK | 1 |
| Coustan-Smith, E; Drexler, HG; Gignac, SM; Hoffbrand, AV; Jani, H | 1 |
| Ase, K; Berry, N; Kikkawa, U; Kishimoto, A; Nishizuka, Y | 1 |
| Hirokawa, M; Kudo, K; Miura, AB; Takahashi, T; Takatsu, H; Yoshida, K | 1 |
| Eto, Y; Shibai, H; Takano, S; Takezawa, M; Tsuji, T; Yokogawa, Y | 1 |
| Drexler, HG; Gaedicke, G; Minowada, J | 3 |
| Drexler, HG; Gaedicke, G; Minowada, J; Novotny, J | 1 |
| Bekesi, JG; Efremidis, AP; Haubenstock, HS; Holland, JF; Papadopoulos, NM | 1 |
| Drexler, HG; Gaedicke, G; Hoffbrand, AV; Minowada, J | 1 |
| Blessinger, C; Mongini, P; Rudich, S; Seremetis, S; Winchester, R | 1 |
| Kasahara, T; Kawai, T; Mukaida, N; Shioiri-Nakano, K; Yagisawa, H | 1 |
| Abrahm, JL; Cassileth, PA; Cooper, RA; Gerson, SL; Hoxie, JA; Tannenbaum, SH | 1 |
| Gabrilove, JL | 1 |
| Breitman, TR; Hemmi, H; Imaizumi, M | 1 |
| Borelli, TJ; Miyamoto, S; Wertheimer, SJ; Wu, JM | 1 |
| Blumenson, L; Krasner, J; Müller, S; Ozer, H | 1 |
| Hirose, M; Kamada, K; Kawano, Y; Miyao, M; Ninomiya, T; Tomimoto, H | 1 |
| Bian, SG; Wang, ZC; Yan, WW | 1 |
| Henning-Chubb, C; Huberman, E; Mitchell, RL; Van Beveren, C; Verma, IM | 1 |
| Feinstein, H; Gazitt, Y; Gurfel, D; Leizerowitz, R; Polliack, A | 1 |
| Caillou, B; Dokhelar, MC; Farace, F; Kieffer, N; Tursz, T; Vainchenker, W | 1 |
| Deli, E; Kiss, Z; Kuo, JF; Vogler, WR | 1 |
| Fukuda, M; Siebert, PD | 1 |
| Lemez, P | 1 |
| Andersson, J; Landegren, U; Wigzell, H | 1 |
| Bekesi, JG; Efremidis, AP; Haubenstock, H; Holland, JF | 1 |
| Ross, DW | 1 |
| Saito, H; Tomioka, H | 1 |
| Arthur, DC; Kersey, JH; Korsmeyer, SJ; Parkin, JL; Stong, RC | 1 |
| Dokhélar, MC; Garson, D; Mishal, Z; Tursz, T; Wakasugi, H | 1 |
| Griffin, JD; Schlossman, SF; Shkolnik, T | 1 |
6 review(s) available for tetradecanoylphorbol acetate and Leukemia
| Article | Year |
|---|---|
[Various factors determining direction of differentiation in leukemic cells].
Topics: Acetamides; Animals; Antineoplastic Agents; Basophils; Carcinogens; Cell Differentiation; Chloroquine; DNA Methylation; Humans; Leukemia; Mice; Tetradecanoylphorbol Acetate; Tretinoin | 1996 |
Prosomes (proteasomes) changes during differentiation are related to the type of inducer.
Topics: Cell Differentiation; Cholecalciferol; Cysteine Endopeptidases; Humans; Leukemia; Multienzyme Complexes; Proteasome Endopeptidase Complex; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1997 |
Effects of interferon on differentiation of normal and tumor cells.
Topics: Adipose Tissue; Animals; Cell Differentiation; Cells, Cultured; Dimethyl Sulfoxide; Hematopoiesis; Humans; Interferons; Leukemia; Leukemia, Erythroblastic, Acute; Melanins; Melanoma; Mice; Muscles; Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin | 1985 |
Differentiation factors.
Topics: Acetamides; Antineoplastic Agents; Calcitriol; Cell Differentiation; Colony-Stimulating Factors; Cytarabine; Humans; Leukemia; Lymphokines; Retinoids; Tetradecanoylphorbol Acetate | 1986 |
Induction by physiological agents of differentiation of the human leukemia cell line HL-60 to cells with functional characteristics.
Topics: Cell Adhesion; Cell Differentiation; Cell Line; Chemotaxis, Leukocyte; Dimethylformamide; Formazans; Humans; Leukemia; Lymphokines; N-Formylmethionine Leucyl-Phenylalanine; Nitroblue Tetrazolium; Oxidation-Reduction; Receptors, Formyl Peptide; Receptors, Immunologic; Tetradecanoylphorbol Acetate; Tretinoin | 1986 |
Leukemic cell maturation.
Topics: Cell Differentiation; Cell Line; Chromosome Aberrations; Chromosome Disorders; Cytarabine; Dimethyl Sulfoxide; Genotype; Hematopoietic Stem Cells; Humans; Leukemia; Leukemia, Myeloid, Acute; Neoplastic Stem Cells; Neutrophils; Oncogenes; Phenotype; Tetradecanoylphorbol Acetate; Vitamin A | 1985 |
269 other study(ies) available for tetradecanoylphorbol acetate and Leukemia
| Article | Year |
|---|---|
Induction of apoptosis and differentiation by atractylenolide-1 isolated from Atractylodes macrocephala in human leukemia cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Atractylodes; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Lactones; Leukemia; Molecular Structure; Sesquiterpenes; Structure-Activity Relationship | 2016 |
MAP kinase-dependent autophagy controls phorbol myristate acetate-induced macrophage differentiation of HL-60 leukemia cells.
Topics: Autophagy; Extracellular Signal-Regulated MAP Kinases; HL-60 Cells; Humans; Leukemia; Macrophages; Tetradecanoylphorbol Acetate | 2022 |
Dynamic Changes in the Ability to Release Neutrophil ExtraCellular Traps in the Course of Childhood Acute Leukemias.
Topics: Acute Disease; Adolescent; Calcium Ionophores; Cells, Cultured; Child; Child, Preschool; Extracellular Traps; Humans; Immunity, Innate; Infant; Leukemia; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Tetradecanoylphorbol Acetate | 2021 |
Identification of fucosylated haptoglobin-producing cells in pancreatic cancer tissue and its molecular mechanism.
Topics: Cell Differentiation; Cell Line, Tumor; Culture Media, Conditioned; Gene Expression Regulation; Glycosylation; Haptoglobins; Humans; Immunohistochemistry; Leukemia; Macrophages; Pancreatic Neoplasms; Protein Precursors; Tetradecanoylphorbol Acetate; THP-1 Cells; Tumor Microenvironment | 2021 |
Ubash3b promotes TPA-mediated suppression of leukemogenesis through accelerated downregulation of PKCδ protein.
Topics: Carcinogenesis; Cell Line, Tumor; Down-Regulation; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Leukemic; Humans; Leukemia; Neoplasm Proteins; Protein Kinase C-delta; Protein Tyrosine Phosphatases; Tetradecanoylphorbol Acetate | 2021 |
Effects of α-conotoxin ImI on TNF-α, IL-8 and TGF-β expression by human macrophage-like cells derived from THP-1 pre-monocytic leukemic cells.
Topics: Animals; Anti-Inflammatory Agents; Cell Differentiation; Cell Proliferation; Cell Survival; Conotoxins; Humans; Interleukin-8; Leukemia; Lipopolysaccharides; Macrophages; Mice; Monocytes; Nicotine; RAW 264.7 Cells; Tetradecanoylphorbol Acetate; THP-1 Cells; Time Factors; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 2017 |
Elastic modulus and migration capability of drug treated leukemia cells K562.
Topics: Antineoplastic Agents; Biomechanical Phenomena; Cell Movement; Cyclophosphamide; Dexamethasone; Elastic Modulus; Humans; K562 Cells; Leukemia; Tetradecanoylphorbol Acetate; Tretinoin | 2019 |
Cytotoxicity of Vitex agnus-castus fruit extract and its major component, casticin, correlates with differentiation status in leukemia cell lines.
Topics: Adult; Apoptosis; Calcitriol; Calcium Channel Agonists; Carcinogens; Cell Adhesion; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Resistance, Neoplasm; Drugs, Chinese Herbal; Flavonoids; HL-60 Cells; Humans; Intercellular Adhesion Molecule-1; Leukemia; Plant Extracts; Tetradecanoylphorbol Acetate; Vitex | 2013 |
A random set approach to confidence regions with applications to the effective dose with combinations of agents.
Topics: Algorithms; Animals; Computer Simulation; Confidence Intervals; Decompression Sickness; HL-60 Cells; Humans; Leukemia; Logistic Models; Methyl Methanesulfonate; Pharmaceutical Preparations; Sheep; Tetradecanoylphorbol Acetate | 2014 |
Synthesis of seco-B-ring bryostatin analogue WN-1 via C-C bond-forming hydrogenation: critical contribution of the B-ring in determining bryostatin-like and phorbol 12-myristate 13-acetate-like properties.
Topics: Animals; Antineoplastic Agents; Bryostatins; Bryozoa; Cell Line, Tumor; Cell Proliferation; Humans; Hydrogenation; Leukemia; Models, Molecular; Protein Kinase C-alpha; Tetradecanoylphorbol Acetate; U937 Cells | 2014 |
Interleukin-32α downregulates the activity of the B-cell CLL/lymphoma 6 protein by inhibiting protein kinase Cε-dependent SUMO-2 modification.
Topics: Cell Line, Tumor; DNA-Binding Proteins; Down-Regulation; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Interleukins; Leukemia; Protein Kinase C-epsilon; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-bcl-6; RNA Interference; Signal Transduction; Small Ubiquitin-Related Modifier Proteins; Sumoylation; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection | 2014 |
Orostachys japonicus inhibits the expression of MMP-2 and MMP-9 mRNA and modulates the expression of iNOS and COX-2 genes in human PMA-differentiated THP-1 cells via inhibition of NF-κB and MAPK activation.
Topics: Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Crassulaceae; Cyclooxygenase 2; Gene Expression Regulation, Leukemic; Humans; Leukemia; MAP Kinase Signaling System; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; NF-kappa B; Nitric Oxide Synthase Type II; Phosphorylation; Plant Extracts; RNA, Messenger; Tetradecanoylphorbol Acetate | 2015 |
Effects of silver nanoparticles and gold nanoparticles on IL-2, IL-6, and TNF-α production via MAPK pathway in leukemic cell lines.
Topics: Blotting, Western; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme-Linked Immunosorbent Assay; Gold; Humans; Interleukin-2; Interleukin-6; Jurkat Cells; Leukemia; Lipopolysaccharides; MAP Kinase Signaling System; Metal Nanoparticles; Mitogen-Activated Protein Kinases; Phytohemagglutinins; Silver; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; U937 Cells | 2015 |
Pathways related to PMA-differentiated THP1 human monocytic leukemia cells revealed by RNA-Seq.
Topics: Cell Differentiation; Cell Line, Tumor; Cluster Analysis; Gene Expression Profiling; Gene Ontology; Humans; Leukemia; Macrophages; Monocytes; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Sequence Analysis, RNA; Signal Transduction; Tetradecanoylphorbol Acetate; Transcriptome | 2015 |
Quantifying MHC dextramer-induced NFAT activation in antigen-specific T cells as a functional response parameter.
Topics: Antigen Presentation; Cytomegalovirus; Flow Cytometry; Fluorescent Dyes; Gene Expression Regulation; Hematopoietic Stem Cell Transplantation; Humans; Image Cytometry; Interferon-gamma; Ionomycin; Leukemia; Lymphocyte Activation; Major Histocompatibility Complex; NFATC Transcription Factors; Phycoerythrin; Primary Cell Culture; Receptors, Antigen, T-Cell; Staining and Labeling; T-Lymphocytes, Cytotoxic; Tetradecanoylphorbol Acetate; Transplant Recipients | 2017 |
Differential expression of Wnt13 isoforms during leukemic cell differentiation.
Topics: CD11b Antigen; Cell Differentiation; Glycoproteins; Humans; K562 Cells; Leukemia; MafB Transcription Factor; Protein Isoforms; RNA, Messenger; Tetradecanoylphorbol Acetate; U937 Cells; Wnt Proteins | 2008 |
Expression of Dlk1 gene in myelodysplastic syndrome determined by microarray, and its effects on leukemia cells.
Topics: Adult; Aged; Antigens, CD34; Apoptosis; Arsenic Trioxide; Arsenicals; Calcium-Binding Proteins; Cell Cycle; Cell Proliferation; Female; Gene Expression Profiling; Gene Expression Regulation; Humans; Intercellular Signaling Peptides and Proteins; K562 Cells; Leukemia; Leukocytes, Mononuclear; Male; Membrane Proteins; Middle Aged; Myelodysplastic Syndromes; Oligonucleotide Array Sequence Analysis; Oxides; Tetradecanoylphorbol Acetate; Up-Regulation | 2008 |
FANTOM studies networks in cells.
Topics: Cell Differentiation; Gene Expression Profiling; Gene Expression Regulation; Gene Regulatory Networks; Humans; Leukemia; Retroelements; RNA, Messenger; Sequence Analysis, RNA; Systems Biology; Tetradecanoylphorbol Acetate; Transcription Factors | 2009 |
Outside-in signal transmission by conformational changes in integrin Mac-1.
Topics: Antibodies, Monoclonal; Apoptosis; Carcinogens; Cell Adhesion; Cell Line, Tumor; Humans; Immunologic Factors; Intercellular Adhesion Molecule-1; Interleukin-8; Leukemia; Leukocytes, Mononuclear; Macrophage-1 Antigen; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Structure, Tertiary; Signal Transduction; Tetradecanoylphorbol Acetate | 2009 |
Effect of propranolol on angiogenic factors in human hematopoietic cell lines in vitro.
Topics: Adrenergic beta-Antagonists; Carcinogens; Enzyme Activation; Humans; Jurkat Cells; Leukemia; Matrix Metalloproteinase 2; Monocytes; Neovascularization, Pathologic; Propranolol; T-Lymphocytes; Tetradecanoylphorbol Acetate; U937 Cells; Vascular Endothelial Growth Factor A | 2009 |
PMA up-regulates the transcription of Axl by AP-1 transcription factor binding to TRE sequences via the MAPK cascade in leukaemia cells.
Topics: Axl Receptor Tyrosine Kinase; Base Sequence; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Humans; Leukemia; MAP Kinase Signaling System; Molecular Sequence Data; Promoter Regions, Genetic; Protein Binding; Proto-Oncogene Proteins; Receptor Protein-Tyrosine Kinases; Response Elements; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Up-Regulation | 2010 |
Up-regulation of ceramide glucosyltransferase during the differentiation of U937 cells.
Topics: Cell Adhesion; Cell Differentiation; Cell Line, Tumor; Galactosyltransferases; Glucosylceramides; Glucosyltransferases; Humans; Leukemia; Macrophages; RNA, Messenger; Tetradecanoylphorbol Acetate; U937 Cells | 2011 |
Profiles of MMP-2 expression in Jurkat, Molt-4 and U937 cells.
Topics: Cell Culture Techniques; Gene Expression Profiling; Humans; Immunomodulation; Jurkat Cells; Leukemia; Leukocytes, Mononuclear; Matrix Metalloproteinase 2; Phytohemagglutinins; Tetradecanoylphorbol Acetate; U937 Cells | 2011 |
The effects of a plant proteinase inhibitor from Enterolobium contortisiliquum on human tumor cell lines.
Topics: Breast Neoplasms; Cell Line, Tumor; Cell Survival; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Fabaceae; Female; Fibroblasts; Humans; Leukemia; Leukocyte Elastase; Matrix Metalloproteinase 14; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mesenchymal Stem Cells; Plant Proteins; Plasminogen; Protease Inhibitors; Tetradecanoylphorbol Acetate; Trypsin Inhibitors | 2011 |
Nature and dynamics of nucleosome release from neoplastic and non-neoplastic cells.
Topics: Apoptosis; Blast Crisis; Cytarabine; Etoposide; Hep G2 Cells; Humans; L-Lactate Dehydrogenase; Leukemia; Neoplasms; Neutrophils; Nucleosomes; Tetradecanoylphorbol Acetate; TNF-Related Apoptosis-Inducing Ligand | 2012 |
PBK/TOPK expression during TPA-induced HL-60 leukemic cell differentiation.
Topics: Antigens, Surface; Apoptosis; Blotting, Western; Carcinogens; Cell Cycle; Cell Differentiation; Cell Membrane; Cell Proliferation; Flow Cytometry; Granulocytes; Humans; Leukemia; Mitogen-Activated Protein Kinase Kinases; Monocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2012 |
p130Cas acts as survival factor during PMA-induced apoptosis in HL-60 promyelocytic leukemia cells.
Topics: Apoptosis; Cell Aggregation; Cell Differentiation; Cell Proliferation; Cell Survival; Crk-Associated Substrate Protein; Gene Expression Regulation, Neoplastic; HL-60 Cells; Humans; Leukemia; Tetradecanoylphorbol Acetate | 2013 |
Sustained activation of MEK1-ERK1/2 pathway in membrane skeleton occurs dependently on cell adhesion in megakaryocytic differentiation.
Topics: Butadienes; Cell Adhesion; Cell Differentiation; Cell Membrane; Enzyme Activation; Enzyme Inhibitors; Kinetics; Leukemia; MAP Kinase Kinase 1; MAP Kinase Signaling System; Megakaryocytes; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Nitriles; Protein Serine-Threonine Kinases; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2002 |
Regulation of prolactin expression in leukemic cell lines and peripheral blood mononuclear cells.
Topics: Adult; Cyclic AMP; Dinoprostone; Gene Expression Regulation; Humans; Ionomycin; Leukemia; Leukocytes, Mononuclear; Middle Aged; Prolactin; Promoter Regions, Genetic; Protein Kinase C; RNA, Messenger; Terbutaline; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2003 |
Superoxide radical generation and Mn- and Cu-Zn superoxide dismutases activities in human leukemic cells.
Topics: Adult; Anions; Child; Humans; Imidazoles; Leukemia; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Leukocytes; Manganese; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Oxidative Stress; Oxygen; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pyrazines; Sodium Dodecyl Sulfate; Superoxide Dismutase; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 2003 |
Regulation of A + U-rich element-directed mRNA turnover involving reversible phosphorylation of AUF1.
Topics: Amino Acid Sequence; Base Sequence; Blotting, Western; Cell Adhesion; Cell Line; Cytoplasm; Dactinomycin; Heterogeneous Nuclear Ribonucleoprotein D0; Heterogeneous-Nuclear Ribonucleoprotein D; Humans; Interleukin-1; Kinetics; Leukemia; Mass Spectrometry; Molecular Sequence Data; Monocytes; Peptides; Phosphorylation; Polyribosomes; Protein Binding; Protein Processing, Post-Translational; Ribonucleases; RNA, Messenger; Sequence Homology, Amino Acid; Serine; Signal Transduction; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2003 |
Regulation of sphingosine kinase 1 gene expression by protein kinase C in a human leukemia cell line, MEG-O1.
Topics: Binding Sites; Cell Line, Tumor; DNA-Binding Proteins; Electrophoretic Mobility Shift Assay; Gene Expression Regulation, Enzymologic; Humans; Leukemia; Mitogen-Activated Protein Kinases; Oligonucleotide Probes; Phosphotransferases (Alcohol Group Acceptor); Promoter Regions, Genetic; Protein Kinase C; Signal Transduction; Sp1 Transcription Factor; Tetradecanoylphorbol Acetate; Transcription Factor AP-2; Transcription Factors; Transcription, Genetic | 2003 |
The neuropeptides vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase activating polypeptide (PACAP) modulate several biochemical pathways in human leukemic myeloid cells.
Topics: Adenosine Triphosphate; Bromodeoxyuridine; Calcium; Cell Line, Tumor; Cyclic AMP; Cytarabine; Cytosol; DNA Fragmentation; Dose-Response Relationship, Drug; Drug Interactions; Electrophoretic Mobility Shift Assay; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Estrenes; Flow Cytometry; Glycophorins; Humans; Immunosuppressive Agents; Inositol Phosphates; Intercellular Adhesion Molecule-1; Leukemia; Myeloid Cells; Neuropeptides; Pituitary Adenylate Cyclase-Activating Polypeptide; Protein Binding; Proto-Oncogene Proteins; Pyrrolidinones; Receptors, Vasoactive Intestinal Peptide; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Thrombin; Time Factors; Transcription Factor AP-1; Vasoactive Intestinal Peptide | 2004 |
Effects of intracellular calcium on cell survival and the MAPK pathway in a human hormone-dependent leukemia cell line (TF-1).
Topics: Calcimycin; Calcium; Calcium-Transporting ATPases; Cell Division; Cell Line, Tumor; Cell Survival; Enzyme Inhibitors; Humans; Indoles; Ionomycin; Leukemia; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Tetradecanoylphorbol Acetate | 2003 |
Impaired nuclear localization of vitamin D receptor in leukemia cells resistant to calcitriol-induced differentiation.
Topics: Active Transport, Cell Nucleus; Calcitriol; Cell Differentiation; Cell Division; Cell Line, Tumor; Drug Resistance, Neoplasm; Humans; Leukemia; Leukemia, Monocytic, Acute; Monocytes; Receptors, Calcitriol; Tetradecanoylphorbol Acetate | 2004 |
Protein kinase Cdelta mediates retinoic acid and phorbol myristate acetate-induced phospholipid scramblase 1 gene expression: its role in leukemic cell differentiation.
Topics: Cell Differentiation; Cell Line, Tumor; Humans; Leukemia; Membrane Proteins; Phospholipid Transfer Proteins; Phosphorylation; Protein Kinase C; Protein Kinase C-delta; RNA, Small Interfering; Tetradecanoylphorbol Acetate; Tretinoin; Up-Regulation | 2004 |
The cyclin-dependent kinase inhibitor p21(CIP1/WAF1) blocks paclitaxel-induced G2M arrest and attenuates mitochondrial injury and apoptosis in p53-null human leukemia cells.
Topics: Antisense Elements (Genetics); Apoptosis; Cell Cycle; Cell Division; Cyclin-Dependent Kinase Inhibitor p21; Doxycycline; Flow Cytometry; G2 Phase; Humans; Jurkat Cells; Leukemia; Membrane Potentials; Mitochondria; Mitotic Index; Paclitaxel; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53; U937 Cells | 2004 |
Expression of glutathione S-transferase P1-1 in leukemic cells is regulated by inducible AP-1 binding.
Topics: Binding Sites; Doxorubicin; Electrophoretic Mobility Shift Assay; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glutathione S-Transferase pi; Glutathione Transferase; Humans; Hydrogen Peroxide; Hydroquinones; Isoenzymes; Jurkat Cells; K562 Cells; Leukemia; Mutagenesis, Site-Directed; Promoter Regions, Genetic; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription, Genetic; Transfection; U937 Cells | 2004 |
The Leukemia-associated ETO homologues are differently expressed during hematopoietic differentiation.
Topics: Bone Marrow Cells; Cell Differentiation; Cell Line; Cell Line, Tumor; DNA Primers; DNA-Binding Proteins; Flow Cytometry; Gene Expression Regulation, Neoplastic; Hematopoietic Stem Cells; HL-60 Cells; Humans; K562 Cells; Kidney; Leukemia; Phosphoproteins; Polymerase Chain Reaction; Proto-Oncogene Proteins; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; Tetradecanoylphorbol Acetate; Transcription Factors; Tretinoin; Tumor Suppressor Proteins; U937 Cells | 2005 |
NUP98-HOXD13 transgenic mice develop a highly penetrant, severe myelodysplastic syndrome that progresses to acute leukemia.
Topics: Acute Disease; Animals; Carcinogens; Cell Differentiation; Cell Transformation, Neoplastic; Disease Models, Animal; Homeodomain Proteins; Humans; K562 Cells; Leukemia; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myelodysplastic Syndromes; Myeloid Ecotropic Viral Integration Site 1 Protein; Neoplasm Proteins; Nuclear Pore Complex Proteins; Penetrance; Phenotype; Severity of Illness Index; Tetradecanoylphorbol Acetate; Transcription Factors; Translocation, Genetic | 2005 |
Differential responses of proliferative and non-proliferative leukemia cells to oxidative stress.
Topics: Apoptosis; Caspase 3; Caspases; Cell Death; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Chromatography, High Pressure Liquid; Cysteine; Dose-Response Relationship, Drug; Glutathione; Glutathione Peroxidase; HL-60 Cells; Humans; Leukemia; Necrosis; Oxidative Stress; Oxygen; Poly(ADP-ribose) Polymerases; Reactive Oxygen Species; Spectrometry, Fluorescence; Sulfhydryl Compounds; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Time Factors | 2005 |
Exocytic responses of single leukaemic human cytotoxic T lymphocytes stimulated by agents that bypass the T cell receptor.
Topics: Cell Degranulation; Cell Line, Tumor; Flow Cytometry; Granzymes; Humans; Leukemia; Lysine; Lysosomal-Associated Membrane Protein 1; Membrane Glycoproteins; Perforin; Pore Forming Cytotoxic Proteins; Receptors, Antigen, T-Cell; Serine Endopeptidases; Stimulation, Chemical; T-Lymphocytes, Cytotoxic; Tetradecanoylphorbol Acetate; Thapsigargin | 2005 |
A survey of the signaling pathways involved in megakaryocytic differentiation of the human K562 leukemia cell line by molecular and c-DNA array analysis.
Topics: Base Sequence; Cell Differentiation; DNA Primers; DNA, Complementary; Enzyme Inhibitors; Humans; Imidazoles; K562 Cells; Leukemia; Megakaryocytes; Mitogen-Activated Protein Kinases; Oligonucleotide Array Sequence Analysis; Polymerase Chain Reaction; Pyridines; Signal Transduction; Tetradecanoylphorbol Acetate | 2006 |
Regulatory properties and cellular redistribution of zinc during macrophage differentiation of human leukemia cells.
Topics: Active Transport, Cell Nucleus; Cell Differentiation; Electron Probe Microanalysis; Gene Expression Profiling; Genetic Variation; HL-60 Cells; Humans; Leukemia; Macrophages; Microscopy, Fluorescence; Myeloid Cells; Protein Kinase C; Protein Kinase C beta; Reproducibility of Results; RNA, Messenger; Spectrometry, Fluorescence; Tetradecanoylphorbol Acetate; Tissue Distribution; Trace Elements; Zinc | 2006 |
PMA and doxorubicin decrease viability, MTT activity and expression of CD10 marker on NALM-1 leukemic cells.
Topics: Antibiotics, Antineoplastic; Antigens, CD20; Biomarkers, Tumor; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Doxorubicin; Enzyme-Linked Immunosorbent Assay; Formazans; Humans; Immunoglobulin mu-Chains; Leukemia; Neprilysin; Syndecan-1; Tetradecanoylphorbol Acetate; Tetrazolium Salts; Time Factors; Tretinoin | 2006 |
PI 3-K signaling pathway suppresses PMA-induced expression of p21WAF1/Cip1 in human leukemia cells.
Topics: Cell Line, Tumor; Chromones; Cyclin-Dependent Kinase Inhibitor p21; Enzyme Activation; Humans; Leukemia; Mitogen-Activated Protein Kinases; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Promoter Regions, Genetic; Protein Binding; Protein Kinase C; Protein Kinases; Signal Transduction; Sirolimus; Sp1 Transcription Factor; Tetradecanoylphorbol Acetate; TOR Serine-Threonine Kinases; Tumor Suppressor Protein p53 | 2007 |
Antioxidant activity of Vaccinium stamineum: exhibition of anticancer capability in human lung and leukemia cells.
Topics: Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Cell Line, Tumor; Cell Proliferation; Chromatography, High Pressure Liquid; Enzyme Activation; Flavonoids; Fruit; Humans; Leukemia; Lung Neoplasms; Mice; Mitogen-Activated Protein Kinases; NF-kappa B; Phosphorylation; Plant Extracts; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Ultraviolet Rays; Vaccinium | 2007 |
A new simple multi-well plate-based assay for monocyte differentiation using human monocytic leukemia THP-1 cells.
Topics: Cell Adhesion; Cell Count; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Humans; Immunoassay; Interferon-gamma; Leukemia; Monocytes; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Scavenger Receptors, Class A; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2007 |
The differentiation/retrodifferentiation program of human U937 leukemia cells is accompanied by changes of VCP/p97.
Topics: Adenosine Triphosphatases; Cell Cycle; Cell Cycle Proteins; Cell Differentiation; Fluorescent Antibody Technique; Gene Expression Regulation, Neoplastic; Humans; Leukemia; Phosphotyrosine; RNA Interference; RNA, Messenger; RNA, Small Interfering; Subcellular Fractions; Tetradecanoylphorbol Acetate; Transfection; U937 Cells; Valosin Containing Protein | 2008 |
Spontaneous production of alpha- and beta-interferon in human lymphoblastoid and lymphoma cell lines.
Topics: Bromodeoxyuridine; Cell Line; Dexamethasone; Dimethyl Sulfoxide; Hematopoiesis; Humans; Interferons; Kinetics; Leukemia; Lymphocytes; Lymphoma; Multiple Myeloma; Tetradecanoylphorbol Acetate | 1982 |
Phorbol ester-induced changes in human leukemic pre-B lines.
Topics: Antigens, Neoplasm; B-Lymphocytes; Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; Humans; Immunoglobulin mu-Chains; Leukemia; Leukemia, Lymphoid; Neprilysin; Phorbols; Stem Cells; Tetradecanoylphorbol Acetate | 1984 |
Megakaryoblastic differentiation of proerythroblastic K562 cell-line cells.
Topics: Butyrates; Cell Differentiation; Cell Line; Glycophorins; Glycoproteins; Humans; Leukemia; Megakaryocytes; Phorbols; Platelet Membrane Glycoproteins; Tetradecanoylphorbol Acetate | 1984 |
Role of T3 surface molecules in human T-cell activation: T3-dependent activation results in an increase in cytoplasmic free calcium.
Topics: Animals; Antibodies, Monoclonal; Antigens; Calcimycin; CD3 Complex; Cell Line; Cell Membrane; Clone Cells; Humans; Interleukin-2; Leukemia; Lymphocyte Activation; Mice; Mutation; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1984 |
Induction of expression and phosphorylation of the human interleukin 2 receptor by a phorbol diester.
Topics: Cell Line; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Flow Cytometry; Glycoside Hydrolases; Humans; Leukemia; Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase; Molecular Weight; Neuraminidase; Phorbols; Phosphorylation; Protein Kinase C; Protein Kinases; Receptors, Immunologic; Receptors, Interleukin-2; Tetradecanoylphorbol Acetate; Trypsin; Tunicamycin | 1984 |
Effect of the diterpene ester TPA on Epstein-Barr virus antigen- and DNA synthesis in producer and nonproducer cell lines.
Topics: Antigens, Viral; Capsid; Cell Line; DNA, Viral; Herpesvirus 4, Human; Humans; Leukemia; Phorbols; Tetradecanoylphorbol Acetate | 1980 |
Can prenatal X-irradiation in mice act as an initiator stimulus in a modified 2-stage Berenblum/Mottram experiment with postnatal promotion with phorbol ester TPA?
Topics: Adenoma; Animals; Carcinoma, Hepatocellular; Cocarcinogenesis; Female; Fetus; Leukemia; Liver Neoplasms; Lung Neoplasms; Maternal-Fetal Exchange; Mice; Ovarian Diseases; Phorbols; Pregnancy; Prostaglandins; Radiation, Ionizing; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; X-Rays | 1980 |
Metabolic heterogeneity of eosinophils from normal and hypereosinophilic patients.
Topics: Eosinophilia; Eosinophils; Hexosephosphates; Humans; Leukemia; Lymphoma; Neoplasms; Sezary Syndrome; Superoxides; Tetradecanoylphorbol Acetate; Time Factors | 1981 |
Tumor promoter 12-O-tetradecanoylphorbol 13-acetate: effect on complement and Epstein-Barr virus receptors in human lymphoblastoid cell lines.
Topics: Burkitt Lymphoma; Cell Line; Herpesvirus 4, Human; Humans; Kinetics; Leukemia; Lymphoma; Phorbols; Receptors, Complement; Receptors, Virus; Rosette Formation; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1982 |
[In vitro differentiation of leukaemic promyelocytes (HL-60): effect on beta-adrenergic receptors and adenylate cyclase activity].
Topics: Adenylyl Cyclases; Cell Differentiation; Cell Line; Cyclic AMP; Granulocytes; Humans; Leukemia; Monocytes; Receptors, Adrenergic; Receptors, Adrenergic, beta; Tetradecanoylphorbol Acetate; Tretinoin | 1983 |
The role of T3 surface molecules in the activation of human T cells: a two-stimulus requirement for IL 2 production reflects events occurring at a pre-translational level.
Topics: Antibodies, Monoclonal; Antigens, Surface; Cell Line; Humans; Interleukin-2; Leukemia; Lymphocyte Activation; Protein Biosynthesis; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor Receptor Superfamily, Member 7 | 1984 |
Ca2+-dependent and phorbol ester activating phosphorylation of a 36K-dalton protein of rat basophilic leukemia cell membranes and immunoprecipitation of the phosphorylated protein with IgE-anti IgE system.
Topics: Amino Acids; Animals; Antibodies, Anti-Idiotypic; Basophils; Calcium; Enzyme Activation; Immunoglobulin E; Leukemia; Molecular Weight; Neoplasm Proteins; Phorbols; Protein Kinases; Rats; Tetradecanoylphorbol Acetate | 1984 |
Monoclonal antibody MCS-2 as the marker of phorbol diester-induced myeloid differentiation in acute undifferentiated leukemia.
Topics: Acute Disease; Antibodies, Monoclonal; Antigens, Surface; Cell Differentiation; Cells, Cultured; Fluorescent Antibody Technique; Humans; Leukemia; Leukocytes; Phorbols; Tetradecanoylphorbol Acetate | 1984 |
Phorbol ester-induced differentiation of a non-T/non-B human leukemic cell line (REH) to macrophage-like cells.
Topics: Cell Differentiation; Cell Line; Fluorescent Antibody Technique; Humans; Leukemia; Lymphocytes; Macrophages; Muramidase; Phagocytosis; Phorbols; Tetradecanoylphorbol Acetate | 1984 |
Leu-10 (HLA-DC/DS) antigen distribution in human leukaemic disorders as detected by a monoclonal antibody: correlation with HLA-DR expression.
Topics: Adult; Antibodies, Monoclonal; Cell Line; Child, Preschool; Female; Fluorescent Antibody Technique; Histocompatibility Antigens Class II; HLA-DQ Antigens; HLA-DR Antigens; Humans; Leukemia; Leukemia, Lymphoid; Lymphoma; Tetradecanoylphorbol Acetate | 1984 |
The induction of Leu-1 antigen expression in human malignant and normal B cells by phorbol myristic acetate (PMA).
Topics: Antigens, Differentiation, B-Lymphocyte; Antigens, Differentiation, T-Lymphocyte; Antigens, Neoplasm; Antigens, Surface; B-Lymphocytes; Cell Differentiation; Humans; Immunoglobulins; Leukemia; Lymphocyte Activation; Lymphoma; Phorbols; Tetradecanoylphorbol Acetate | 1984 |
Transcriptional regulation of a tumor promoter and mitogen-inducible gene in human lymphocytes.
Topics: Cells, Cultured; Gene Expression Regulation; Genes; Humans; Leukemia; Lymphocytes; Phorbols; Phytohemagglutinins; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1984 |
Differentiation of human leukemia cells and its usefulness for clinical diagnosis.
Topics: Cell Differentiation; Clinical Laboratory Techniques; Diagnosis, Differential; Humans; Leukemia; Leukemia, Hairy Cell; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukemia, Plasma Cell; Tetradecanoylphorbol Acetate | 1983 |
Analysis of the binding of peanut agglutinin (PNA) to leukaemic cells and its relationship to T-cell differentiation.
Topics: Cell Differentiation; Cell Line; Chromatography, Affinity; Humans; Lectins; Leukemia; Lymphocytes; Microscopy, Fluorescence; Peanut Agglutinin; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1983 |
Stimulation of cell proliferation by tumor-promoting phorbol esters and inhibition by some inhibitors of tumor promotion in suspension cultures of a human lymphoblastoid cell line.
Topics: B-Lymphocytes; Bone Marrow; Cell Division; Cell Line; Cells, Cultured; Diterpenes; Humans; Leukemia; Phorbols; Tetradecanoylphorbol Acetate | 1983 |
Sézary cells with an unusual phenotype, their modulation with 12-O-tetradecanoyl phorbol-13-acetate (TPA) in vitro, and their relationship to T-cell development.
Topics: Aged; Antibodies, Monoclonal; B-Lymphocytes; Humans; Leukemia; Male; Phenotype; Phorbols; Receptors, Antigen, B-Cell; Sezary Syndrome; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1983 |
Differentiation of human leukemic cell lines (HL60, U937) toward macrophages is accompanied by production of colony-stimulating activity (CSA).
Topics: Cell Differentiation; Cell Line; Colony-Stimulating Factors; Humans; Leukemia; Macrophage Activation; Neoplastic Stem Cells; Tetradecanoylphorbol Acetate | 1984 |
Distinctive phorbol ester-induced morphological and surface antigen changes in mycosis fungoides, the Sézary syndrome, and adult T-cell leukemia.
Topics: Adult; Antigens, Surface; Cell Transformation, Neoplastic; Cells, Cultured; Humans; Kinetics; Leukemia; Mycosis Fungoides; Phenotype; Phorbols; Sezary Syndrome; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1984 |
Progression of mouse thymic leukemias in thymic microenvironments.
Topics: Animals; Cell Communication; Leukemia; Mice; Tetradecanoylphorbol Acetate; Thymus Gland; Thymus Neoplasms | 1983 |
Differentiation-associated changes in human non-T, non-B leukemia cell lines after treatment with 12-O-tetradecanoylphorbol 13-acetate (TPA).
Topics: Acid Phosphatase; Antigens, Neoplasm; Cell Differentiation; Cell Division; Cell Line; Glucuronidase; Humans; Leukemia; Phorbols; Tetradecanoylphorbol Acetate | 1984 |
Preferential growth inhibition of human leukemic versus normal myeloid colony-forming cells by 12-O-tetradecanoylphorbol-13-acetate.
Topics: Cell Differentiation; Cells, Cultured; Hematopoietic Stem Cells; Humans; Leukemia; Phorbols; Tetradecanoylphorbol Acetate | 1984 |
Induction of antibody-dependent and nonspecific tumor killing in human monocytic leukemia cells by nonlymphocyte factors and phorbol ester.
Topics: Antibody-Dependent Cell Cytotoxicity; Cell Line; Humans; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lymphoma, Large B-Cell, Diffuse; Phagocytosis; Phorbols; Receptors, Complement; Receptors, Fc; Tetradecanoylphorbol Acetate; Urinary Bladder Neoplasms | 1982 |
Effects of 12-O-tetradecanoylphorbol-13-acetate on the proliferation and differentiation of normal and leukemic myeloid progenitor cells.
Topics: Bone Marrow; Cell Differentiation; Cell Division; Cells, Cultured; Culture Media; Cytarabine; Humans; Leukemia; Macrophages; Neutrophils; Phorbols; Tetradecanoylphorbol Acetate | 1983 |
Differentiation of human leukemias in response to 12-0-tetradecanoylphorbol-13-acetate in vitro.
Topics: Cell Adhesion; Cell Aggregation; Cell Transformation, Neoplastic; Esterases; Humans; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Phagocytosis; Phorbols; Tetradecanoylphorbol Acetate | 1980 |
Induction by tumor-promoting phorbol diester of colony-stimulating activity in human myeloid leukemia cells transformed to macrophage-mimicking cells.
Topics: Bone Marrow; Cell Adhesion; Cell Division; Cell Line; Colony-Stimulating Factors; Granulocytes; Humans; Leukemia; Leukemia, Myeloid; Macrophages; Phorbols; Tetradecanoylphorbol Acetate | 1981 |
Specific changes in the surface glycoprotein pattern of a human leukemic null cell line NALL-1 associated with morphologic and biological alterations induced by phorbol-ester.
Topics: Cell Division; Cell Line; Cell Membrane; DNA, Neoplasm; Fluorescent Antibody Technique; Glycoproteins; Humans; Kinetics; Leukemia; Membrane Proteins; Molecular Weight; Neoplasm Proteins; Phorbols; RNA, Neoplasm; Tetradecanoylphorbol Acetate | 1980 |
Unique cell surface glycoprotein expression in hairy cell leukemia: effect of phorbol ester tumor promoters on surface glycoproteins, cell morphology, and adherence.
Topics: Adult; Aged; Cell Adhesion; Cells, Cultured; Female; Glycoproteins; Humans; Leukemia; Leukemia, Hairy Cell; Male; Membrane Proteins; Middle Aged; Neoplasm Proteins; Phorbol Esters; Phorbols; Primary Myelofibrosis; Tetradecanoylphorbol Acetate | 1982 |
Tumor-promoting phorbol diester-induced specific changes in cell surface glycoprotein profile of K562 human leukemic cells.
Topics: Cell Count; Cell Differentiation; Cell Line; Cell Membrane; Electrophoresis, Polyacrylamide Gel; Glycophorins; Glycoproteins; Humans; Leukemia; Membrane Proteins; Phorbols; Tetradecanoylphorbol Acetate | 1981 |
Fatty acid metabolism in phorbol ester-differentiating human leukemia cells.
Topics: Carcinogens; Cell Differentiation; Cell Line; Fatty Acids; Humans; Leukemia; Lipid Metabolism; Phorbols; Tetradecanoylphorbol Acetate | 1981 |
The active monomeric form of macrophage inflammatory protein-1 alpha interacts with high- and low-affinity classes of receptors on human hematopoietic cells.
Topics: Antigens, CD; Antigens, CD34; Binding, Competitive; Chemokine CCL4; Cross-Linking Reagents; Cytokines; Granulocytes; Hematopoietic Stem Cells; Humans; Kinetics; Leukemia; Macrophage Inflammatory Proteins; Molecular Weight; Monocytes; Monokines; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Receptors, Chemokine; Receptors, Immunologic; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Expression of axl, a transforming receptor tyrosine kinase, in normal and malignant hematopoiesis.
Topics: Axl Receptor Tyrosine Kinase; Base Sequence; Bone Marrow; Cell Differentiation; Flow Cytometry; Gene Expression; Hematopoiesis; Humans; Interferon-alpha; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Molecular Sequence Data; Monocytes; Myelodysplastic Syndromes; Oncogene Proteins; Polymerase Chain Reaction; Proto-Oncogene Proteins; Receptor Protein-Tyrosine Kinases; RNA-Directed DNA Polymerase; RNA, Messenger; Tetradecanoylphorbol Acetate | 1994 |
Effects of cyclic AMP on expression of LFA-1, Mac-1, and VLA-4 and eosinophilic differentiation of a human leukemia cell line, EoL-1.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Antigens, CD; Bucladesine; Butyrates; Cell Differentiation; Cell Division; Cyclic AMP; Eosinophils; Fluorescent Antibody Technique; Granulocyte Colony-Stimulating Factor; Humans; Integrin beta1; Integrins; Isoquinolines; Leukemia; Lymphocyte Function-Associated Antigen-1; Macrophage-1 Antigen; Piperazines; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1994 |
Alterations in expression of p56lck during myeloid differentiation of LSTRA cells.
Topics: Antigens, Differentiation; Bucladesine; Carboxylesterase; Carboxylic Ester Hydrolases; Cell Cycle; Cell Differentiation; Cholecalciferol; Enzyme Induction; Granulocytes; Hematopoietic Stem Cells; Histocompatibility Antigens Class II; Humans; Leukemia; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Macrophages; N-Formylmethionine Leucyl-Phenylalanine; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine | 1994 |
Does thalidomide affect IL-2 response and production?
Topics: beta-Galactosidase; Cells, Cultured; Clone Cells; Dose-Response Relationship, Drug; Enhancer Elements, Genetic; Enzyme-Linked Immunosorbent Assay; Humans; Interleukin-2; Ionomycin; Kinetics; Leukemia; Lymphocyte Activation; Lymphocytes; Tetradecanoylphorbol Acetate; Thalidomide; Transfection; Tumor Cells, Cultured | 1995 |
Expression of multidrug resistance in response to differentiation in the K562 human leukaemia cell line.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Butyrates; Butyric Acid; Cell Differentiation; Cell Survival; Colchicine; Drug Resistance, Multiple; Epirubicin; Humans; Leukemia; Phenotype; Rhodamine 123; Rhodamines; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Verapamil | 1995 |
Cell cycle progression and phenotypic modification of Ki67 antigen-negative G1- and G2-phase cells in phorbol ester-treated Molt-4 human leukemia cells.
Topics: Antigens, CD; Cell Cycle; Cell Differentiation; Cell Division; Flow Cytometry; G1 Phase; G2 Phase; Humans; Ki-67 Antigen; Kinetics; Leukemia; Neoplasm Proteins; Nuclear Proteins; Phenotype; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Enhancement of phorbol ester-induced production of tumor necrosis factor-alpha by 2,6-dimethylphenylphthalimide.
Topics: Cell Division; Humans; Leukemia; Phthalimides; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Xylenes | 1994 |
A possible role of 92 kDa type IV collagenase in the extramedullary tumor formation in leukemia.
Topics: Collagenases; Glycoproteins; Humans; Interferon-alpha; Interleukin-1; Interleukin-6; Leukemia; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Neoplasm Metastasis; Sarcoma; Tetradecanoylphorbol Acetate; Tissue Inhibitor of Metalloproteinases; Transforming Growth Factor beta; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1995 |
Modulation of poly(ADP-ribose) polymerase during neutrophilic and monocytic differentiation of promyelocytic (NB4) and myelocytic (HL-60) leukaemia cells.
Topics: Calcitriol; Cell Differentiation; Cell Division; Humans; Leukemia; Monocytes; Neutrophils; Poly(ADP-ribose) Polymerases; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1995 |
Expression of the CR1 receptor on human leukemia-derived CD4+ T cell lines.
Topics: CD4-Positive T-Lymphocytes; Cell Cycle; Flow Cytometry; Humans; Leukemia; Phytohemagglutinins; Radioimmunoassay; Receptors, Complement 3b; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Phorbol ester induction of differentiation and apoptosis in the K562 cell line is accompanied by marked decreases in the stability of globin mRNAs and decreases in the steady state level of mRNAs encoding for ribosomal proteins L35, L31, L27, and L21.
Topics: Apoptosis; Base Sequence; Cell Differentiation; Cycloheximide; DNA, Complementary; Gene Expression Regulation, Neoplastic; Globins; Half-Life; Humans; Leukemia; Models, Biological; Molecular Sequence Data; Polymerase Chain Reaction; Protein Kinase C; Ribosomal Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Overexpression of protein kinase C-zeta stimulates leukemic cell differentiation.
Topics: Antigens, CD; Cell Adhesion; Cell Differentiation; Cell Division; Cell Size; Gene Expression; Humans; Isoenzymes; Leukemia; Lysosomes; Monocytes; Protein Kinase C; Proto-Oncogene Proteins c-jun; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transfection; Tumor Cells, Cultured | 1994 |
Posttranscriptional stabilization underlies p53-independent induction of p21WAF1/CIP1/SDI1 in differentiating human leukemic cells.
Topics: Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Dimethyl Sulfoxide; Gene Expression Regulation, Neoplastic; Granulocytes; Humans; Leukemia; Monocytes; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tretinoin; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 1995 |
Regulation and specificity of MNDA expression in monocytes, macrophages, and leukemia/B lymphoma cell lines.
Topics: Antigens, Differentiation, Myelomonocytic; B-Lymphocytes; Burkitt Lymphoma; Cell Line; Endotoxins; Gene Expression Regulation, Leukemic; Herpesvirus 4, Human; Humans; Interferon-alpha; Leukemia; Macrophages; Monocytes; Philadelphia Chromosome; Phorbol Esters; Phytohemagglutinins; Tetradecanoylphorbol Acetate; Transcription Factors; Tumor Cells, Cultured | 1994 |
N-Alkylphthalimides: structural requirement of thalidomidal action on 12-O-tetradecanoylphorbol-13-acetate-induced tumor necrosis factor alpha production by human leukemia HL-60 cells.
Topics: Humans; Leukemia; Phthalimides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1995 |
Modulation of phorbol ester-induced HL-60 differentiation by prostaglandin E2.
Topics: Carcinogenicity Tests; Carcinogens; Cell Differentiation; Cell Separation; Cell Transformation, Neoplastic; Dinoprostone; Dose-Response Relationship, Drug; Drug Synergism; Fibroblasts; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Leukemia; Phagocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Soluble interleukin-2 receptor, soluble CD8 and soluble intercellular adhesion molecule-1 levels in hematologic malignancies.
Topics: Antigens, CD; Biomarkers; Biomarkers, Tumor; CD8 Antigens; Cell Adhesion Molecules; Cell Line; Enzyme-Linked Immunosorbent Assay; Humans; Intercellular Adhesion Molecule-1; Leukemia; Leukemia, Hairy Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid, Acute; Leukemia, Prolymphocytic; Leukemia, T-Cell; Mycosis Fungoides; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Receptors, Interleukin-2; Recurrence; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Partial characterization of human leukemia U-937 cell sublines resistant to 9-nitrocamptothecin.
Topics: Animals; Antineoplastic Agents; Camptothecin; Cell Adhesion; Cell Differentiation; Cell Division; DNA Topoisomerases, Type I; DNA, Neoplasm; Drug Resistance; Flow Cytometry; Humans; Leukemia; Male; Mice; Mice, Nude; Monocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
GS-X pump is functionally overexpressed in cis-diamminedichloroplatinum (II)-resistant human leukemia HL-60 cells and down-regulated by cell differentiation.
Topics: Adenosine Triphosphate; Biological Transport; Carrier Proteins; Cell Differentiation; Cisplatin; Dimethyl Sulfoxide; Down-Regulation; Drug Resistance; Glutathione; Humans; Leukemia; Membrane Proteins; Membrane Transport Proteins; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1994 |
Calcium-mediated induction of anergy in the Jurkat T-cell line.
Topics: Calcium; Cell Line; Cell Survival; Clonal Anergy; Humans; Interleukin-2; Leukemia; Lymphocyte Activation; Muromonab-CD3; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Decrease in equilibrative uridine transport during monocytic differentiation of HL-60 leukaemia: involvement of protein kinase C.
Topics: Affinity Labels; Alkaloids; Binding Sites; Biological Transport; Cell Differentiation; Dilazep; Dipyridamole; Humans; Kinetics; Leukemia; Monocytes; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Thioinosine; Thymidine; Tumor Cells, Cultured; Uracil; Uridine | 1994 |
Inhibition of calcium-dependent protein kinase C by hexadecylphosphocholine and 1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine do not correlate with inhibition of proliferation of HL60 and K562 cell lines.
Topics: Antineoplastic Agents; Cell Division; Cell Membrane; Cytosol; Diglycerides; Dose-Response Relationship, Drug; Humans; Leukemia; Phospholipid Ethers; Phosphorylcholine; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Alteration of nm23 gene expression during the induced differentiation of human leukemia cell lines.
Topics: Animals; Base Sequence; Cell Differentiation; Gene Expression Regulation, Leukemic; Humans; Leukemia; Mice; Molecular Sequence Data; Monomeric GTP-Binding Proteins; NM23 Nucleoside Diphosphate Kinases; Nucleoside-Diphosphate Kinase; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription Factors; Transfection; Tumor Cells, Cultured | 1994 |
Protein kinase C-beta is required for macrophage differentiation of human HL-60 leukemia cells.
Topics: Cell Differentiation; DNA, Complementary; Drug Resistance; Humans; Leukemia; Macrophages; Phenotype; Protein Kinase C; Protein Kinase C beta; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1994 |
Wilms' tumor gene, WT1, mRNA is down-regulated during induction of erythroid and megakaryocytic differentiation of K562 cells.
Topics: Antigens, Differentiation; Base Sequence; Blotting, Northern; Bryostatins; Cell Differentiation; Cell Division; Cell Line, Transformed; DNA Probes; Erythrocytes; Genes, Wilms Tumor; Humans; Lactones; Leukemia; Macrolides; Megakaryocytes; Molecular Sequence Data; RNA, Messenger; Tetradecanoylphorbol Acetate | 1994 |
Extramedullary tumor as presentation of leukemia: establishment of a new human GPIIb- and GPIIIa-positive leukemia cell line.
Topics: Adult; Antigens, Surface; Blotting, Northern; Cell Differentiation; Cell Division; Cytokines; DNA, Neoplasm; Flow Cytometry; Humans; Immunophenotyping; Karyotyping; Leukemia; Male; Megakaryocytes; Microscopy, Electron; Platelet Membrane Glycoproteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Phosphorylation of ribosomal protein S6 and its regulation during differentiation of human leukemic cells.
Topics: Cell Differentiation; Humans; Leukemia; Macrophage Colony-Stimulating Factor; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Ribosomal Protein S6; Ribosomal Proteins; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Effects of chronic phorbol ester treatment on protein kinase C activity, content, and gene expression in the human monoblastoid U937 cell.
Topics: Base Sequence; beta-Galactosidase; Binding Sites; Blotting, Western; Brain; Cell Differentiation; Cell Line; Chloramphenicol O-Acetyltransferase; Collagenases; DNA-Binding Proteins; Dose-Response Relationship, Drug; Early Growth Response Protein 1; Enhancer Elements, Genetic; Gene Expression; Genes, jun; Humans; Immediate-Early Proteins; Kinetics; Leukemia; Molecular Sequence Data; Oligodeoxyribonucleotides; Promoter Regions, Genetic; Protein Kinase C; Proto-Oncogene Proteins c-jun; Proto-Oncogenes; Tetradecanoylphorbol Acetate; Transcription Factors; Transfection; Tumor Cells, Cultured | 1994 |
The phospholipase-A2 reaction leads to increased monocyte adhesion of endothelial cells via the expression of adhesion molecules.
Topics: Cell Adhesion; Cell Adhesion Molecules; Cell Line; Endothelium, Vascular; Enzyme Activation; Enzyme-Linked Immunosorbent Assay; Humans; Interleukin-1; Leukemia; Lipopolysaccharides; Lysophosphatidylcholines; Monocytes; Phosphatidylcholines; Phospholipases A; Phospholipases A2; Recombinant Proteins; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Umbilical Cord | 1993 |
Expression and modulation of annexin VIII in human leukemia-lymphoma cell lines.
Topics: Annexins; Blotting, Northern; Bryostatins; Cell Differentiation; Cholecalciferol; Dactinomycin; Gene Expression Regulation, Neoplastic; Half-Life; Humans; Lactones; Leukemia; Leukemia, Myeloid; Leukemia, Promyelocytic, Acute; Lymphoma; Macrolides; RNA, Messenger; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1993 |
Different mechanisms of inhibition by alkyl-lysophospholipid and phorbol ester of granulocyte-macrophage colony-stimulating factor binding to human leukemic cell lines.
Topics: Antineoplastic Agents; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Iodine Radioisotopes; Leukemia; Leukemia, Experimental; Phospholipid Ethers; Protein Binding; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Thermal stress as an inducer of differentiation of U937 cells.
Topics: Calcitriol; Cell Differentiation; Cell Division; Hot Temperature; Humans; Kinetics; Leukemia; Luminescent Measurements; Lymphoma, Large B-Cell, Diffuse; Monocytes; Tetradecanoylphorbol Acetate; Time Factors; Tretinoin; Tumor Cells, Cultured; Zymosan | 1993 |
IFN-gamma and TNF-alpha secretion by CD4+ and CD8+ TCR alpha beta + T-cell clones derived early after allogeneic bone marrow transplantation.
Topics: Adult; Bone Marrow Transplantation; CD4 Antigens; CD8 Antigens; Clone Cells; Female; Humans; Interferon-gamma; Leukemia; Male; Middle Aged; Receptors, Antigen, T-Cell; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1993 |
Interactions between human immunodeficiency virus infection and hormonal pathways: enhancement of calcium-induced but reduction of glucocorticoid-induced cell death.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Alprostadil; Apoptosis; Bucladesine; Calcimycin; Calcium; Cell Death; Dexamethasone; Glucocorticoids; HIV-1; Humans; Leukemia; Protein Kinase C; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Differential inhibition of the DNA binding of transcription factors NF kappa B and OTF-1 by nitrogen mustard and quinacrine mustard: transcriptional implications.
Topics: Base Composition; Base Sequence; Chloramphenicol O-Acetyltransferase; DNA-Binding Proteins; HIV Long Terminal Repeat; Host Cell Factor C1; Humans; Leukemia; Mechlorethamine; Molecular Sequence Data; NF-kappa B; Octamer Transcription Factor-1; Oligonucleotide Probes; Phytohemagglutinins; Promoter Regions, Genetic; Quinacrine Mustard; Tetradecanoylphorbol Acetate; Transcription Factors; Tumor Cells, Cultured | 1993 |
Up-regulation of small GTP-binding proteins smg P21A and ras P21S during TPA-induced differentiation of human leukemia cell lines.
Topics: Cell Differentiation; GTP-Binding Proteins; Humans; In Vitro Techniques; Leukemia; Macrophage-1 Antigen; Platelet Membrane Glycoproteins; Proto-Oncogene Proteins p21(ras); rap GTP-Binding Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 1993 |
cDNA cloning of a human mRNA preferentially expressed in hematopoietic cells and with homology to a GDP-dissociation inhibitor for the rho GTP-binding proteins.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cattle; Cell Differentiation; Cell Line; Cloning, Molecular; DNA; DNA, Neoplasm; GTP-Binding Proteins; Guanosine Diphosphate; Hematopoiesis; Hematopoietic Stem Cells; Humans; Leukemia; Leukemia, Experimental; Mice; Molecular Sequence Data; RNA, Messenger; Sequence Homology, Amino Acid; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 1993 |
Transcript levels of thymosin beta 4, an actin-sequestering peptide, in cell proliferation.
Topics: Actins; Animals; Calcimycin; Cell Division; Concanavalin A; Gene Expression; Humans; Leukemia; Liver; Liver Regeneration; Lymphocytes; Peptides; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tetradecanoylphorbol Acetate; Thymosin; Thymus Gland; Time Factors | 1993 |
Programmed cell death induced by ceramide.
Topics: Apoptosis; Ceramides; DNA; DNA Damage; Leukemia; Nucleosomes; Protein Kinase C; Sphingomyelins; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Zinc | 1993 |
Human leukemia cell lines bind basic fibroblast growth factor (FGF) on FGF receptors and heparan sulfates: downmodulation of FGF receptors by phorbol ester.
Topics: Animals; Binding Sites; CHO Cells; Cricetinae; Down-Regulation; Fibroblast Growth Factor 2; Heparan Sulfate Proteoglycans; Heparin; Heparitin Sulfate; HL-60 Cells; Humans; Leukemia; Leukemia, Megakaryoblastic, Acute; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Lymphoma, Large B-Cell, Diffuse; Megakaryocytes; Neoplasm Proteins; Protein Binding; Proteoglycans; Receptors, Fibroblast Growth Factor; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1996 |
Phorbol ester (TPA)-induced differential modulation of cell surface antigens in human pluripotential leukemia (K-562) cell line: effects of protein kinase inhibitors with broad- and PKC selective inhibitory activity.
Topics: Alkaloids; Antigens, CD; CD59 Antigens; Humans; Intercellular Adhesion Molecule-1; Leukemia; Leukocyte Common Antigens; Lymphocyte Function-Associated Antigen-1; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Constitutively active MAP kinase kinase (MEK1) stimulates SAP kinase and c-Jun transcriptional activity in U937 human leukemic cells.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Cycle Proteins; Cell Differentiation; Cell Division; Cell Line; Dual Specificity Phosphatase 1; Enzyme Activation; Enzyme Induction; Haplorhini; Humans; Immediate-Early Proteins; JNK Mitogen-Activated Protein Kinases; Leukemia; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Mutation; Phosphoprotein Phosphatases; Protein Kinase Inhibitors; Protein Kinases; Protein Phosphatase 1; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins c-jun; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 1995 |
Synthesis, processing, and intracellular transport of CD36 during monocytic differentiation.
Topics: Antibodies, Monoclonal; Antigens, CD; Blotting, Western; CD36 Antigens; Cell Differentiation; Cell Line; Electrophoresis, Polyacrylamide Gel; Flow Cytometry; Gene Expression; Glycoside Hydrolases; HL-60 Cells; Humans; Kinetics; Leukemia; Monocytes; Protein Processing, Post-Translational; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1996 |
CD28-mediated cytotoxicity by the human leukemic NK cell line YT involves tyrosine phosphorylation, activation of phosphatidylinositol 3-kinase, and protein kinase C.
Topics: Amino Acid Sequence; CD28 Antigens; Cross-Linking Reagents; Cytoplasmic Granules; Cytotoxicity, Immunologic; Enzyme Activation; Humans; Isoenzymes; Killer Cells, Natural; Leukemia; Molecular Sequence Data; Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Protein Kinase C; Protein-Tyrosine Kinases; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1996 |
Megakaryocytic differentiation of a leukemic cell line, MC3, by phorbol ester: induction of glycoprotein IIb/IIIa and effects on expression of IL-6, IL-6 receptor, mpl and GATA genes.
Topics: Antigens, CD; Base Sequence; Blotting, Northern; Cell Differentiation; DNA-Binding Proteins; Erythroid-Specific DNA-Binding Factors; GATA1 Transcription Factor; GATA2 Transcription Factor; Gene Expression Regulation, Leukemic; Humans; Interleukin-6; Leukemia; Megakaryocytes; Molecular Sequence Data; Neoplasm Proteins; Platelet Glycoprotein GPIIb-IIIa Complex; Polymerase Chain Reaction; Proto-Oncogene Proteins; Receptors, Cytokine; Receptors, Interleukin; Receptors, Interleukin-6; Receptors, Thrombopoietin; Tetradecanoylphorbol Acetate; Transcription Factors; Tumor Cells, Cultured | 1995 |
Physical and functional association of cortactin with Syk in human leukemic cell line K562.
Topics: Antibodies, Monoclonal; Cell Differentiation; Cortactin; Enzyme Activation; Enzyme Precursors; Humans; Intracellular Signaling Peptides and Proteins; Leukemia; Microfilament Proteins; Phosphorylation; Protein-Tyrosine Kinases; Syk Kinase; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine | 1996 |
Expression of megakaryocytic and erythroid properties in human leukemic cells.
Topics: Antigens, CD; Antigens, Differentiation; Antigens, Differentiation, Myelomonocytic; Antigens, Neoplasm; Antigens, Surface; Blood Platelets; Blood Proteins; Cell Adhesion Molecules; Cell Differentiation; Erythrocyte Membrane; Erythrocytes; Flow Cytometry; Hematopoietic Cell Growth Factors; Hematopoietic Stem Cells; Humans; Leukemia; Leukemia, Erythroblastic, Acute; Megakaryocytes; Membrane Glycoproteins; Microscopy, Fluorescence; Neoplasm Proteins; Neoplastic Stem Cells; Platelet Endothelial Cell Adhesion Molecule-1; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1996 |
Differential expression of the ufo/axl oncogene in human leukemia-lymphoma cell lines.
Topics: 3T3 Cells; Animals; Axl Receptor Tyrosine Kinase; Cell Differentiation; Gene Expression Regulation, Leukemic; Half-Life; HeLa Cells; Hematopoietic Stem Cells; Humans; KB Cells; Leukemia; Lymphoma; Mice; Neoplasm Proteins; Oncogene Proteins; Proto-Oncogene Proteins; Receptor Protein-Tyrosine Kinases; RNA, Messenger; RNA, Neoplasm; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 1996 |
Expression of receptor protein tyrosine kinase tif is regulated during leukemia cell differentiation.
Topics: Acetamides; Base Sequence; Cell Differentiation; Down-Regulation; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Leukemic; Humans; Leukemia; Leukemia, Erythroblastic, Acute; Leukemia, Megakaryoblastic, Acute; Molecular Sequence Data; Phosphorylation; Receptor Protein-Tyrosine Kinases; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1996 |
Induction of CD38/NADase and its monoclonal antibody-induced tyrosine phosphorylation in human leukemia cell lines.
Topics: ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Antibodies, Monoclonal; Antigens, CD; Antigens, Differentiation; Bucladesine; Cell Differentiation; Cell Line; HL-60 Cells; Humans; Kinetics; Leukemia; Membrane Glycoproteins; N-Glycosyl Hydrolases; NAD+ Nucleosidase; Phosphoproteins; Phosphorylation; Phosphotyrosine; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1996 |
Expression of the endogenous retrovirus ERV3 (HERV-R) during induced monocytic differentiation in the U-937 cell line.
Topics: Calcitriol; Cell Differentiation; Gene Products, env; Humans; Interferon-gamma; Leukemia; Monocytes; Retroviridae; RNA, Messenger; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1996 |
Dimethyl sulfoxide-induced apoptosis in human leukemic U937 cells.
Topics: Apoptosis; Cell Line; Cell Membrane; Cell Survival; Cycloheximide; Dactinomycin; Dimethyl Sulfoxide; DNA, Neoplasm; Electrophoresis, Agar Gel; Flow Cytometry; Humans; Kinetics; Leukemia; Protein Kinase C; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured; Zinc | 1996 |
Protein kinase C modulates cytosolic free calcium by stimulating calcium pump activity in Jurkat T cells.
Topics: Alkaloids; Calcium; Calcium-Transporting ATPases; Cytosol; Enzyme Inhibitors; Fluorescent Dyes; Fura-2; Humans; Ionomycin; Ionophores; Lanthanum; Leukemia; Naphthalenes; Phorbol Esters; Protein Kinase C; Sodium; Staurosporine; T-Lymphocytes; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Tumor Cells, Cultured | 1995 |
Regulation of the plasminogen activator inhibitor type-2 gene in monocytes: localization of an upstream transcriptional silencer.
Topics: Base Sequence; Chloramphenicol O-Acetyltransferase; Fibrosarcoma; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Genes, Reporter; HeLa Cells; Humans; Leukemia; Lymphoma, Large B-Cell, Diffuse; Macrophages; Molecular Sequence Data; Monocytes; Neoplasm Proteins; Plasminogen Activator Inhibitor 2; Promoter Regions, Genetic; Regulatory Sequences, Nucleic Acid; Sequence Deletion; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 1996 |
Phorbol ester PMA induces expression of the thrombopoietin receptor MPL in leukemia cells.
Topics: Biomarkers; Cell Differentiation; Cell Division; Humans; Leukemia; Megakaryocytes; Neoplasm Proteins; Proto-Oncogene Proteins; Receptors, Cytokine; Receptors, Thrombopoietin; Tetradecanoylphorbol Acetate; Thrombopoietin; Tumor Cells, Cultured; Up-Regulation | 1996 |
Altered expression of the developmentally regulated NFI gene family during phorbol ester-induced differentiation of human leukemic cells.
Topics: Base Sequence; Binding Sites; CCAAT-Enhancer-Binding Proteins; Cell Differentiation; Cloning, Molecular; Cycloheximide; DNA Probes; DNA-Binding Proteins; Humans; Leukemia; Molecular Sequence Data; NFI Transcription Factors; Nuclear Proteins; Protein Synthesis Inhibitors; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription Factors; Tumor Cells, Cultured; Y-Box-Binding Protein 1 | 1996 |
Fructose 2,6-bisphosphate metabolism during megakaryocytic differentiation of K562 and MEG-01 cells.
Topics: Carcinogens; Cell Differentiation; Fructosediphosphates; Humans; Leukemia; Megakaryocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1996 |
Inhibition of GTP gamma S-dependent phospholipase D and Rho membrane association by calphostin is independent of protein kinase C catalytic activity.
Topics: Blotting, Western; Cell Membrane; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; GTP-Binding Proteins; GTPase-Activating Proteins; Guanosine 5'-O-(3-Thiotriphosphate); HL-60 Cells; Humans; Indoles; Leukemia; Liposomes; Maleimides; Naphthalenes; Permeability; Phospholipase D; Plants; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1997 |
Geranylgeraniol potently induces caspase-3-like activity during apoptosis in human leukemia U937 cells.
Topics: Apoptosis; Caspase 3; Caspases; Cysteine Endopeptidases; Diterpenes; Enzyme Induction; Humans; Leukemia; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1997 |
Activation of protein kinase C prevents induction of apoptosis by geranylgeraniol in human leukemia HL60 cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Animals; Apoptosis; Diglycerides; Diterpenes; Enzyme Activation; Enzyme Inhibitors; HL-60 Cells; Humans; Leukemia; Mice; Neoplasm Proteins; Phorbol Esters; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1997 |
Human A1, a Bcl-2-related gene, is induced in leukemic cells by cytokines as well as differentiating factors.
Topics: Cell Differentiation; Cloning, Molecular; Gene Expression Regulation; Hematopoietic Stem Cells; Humans; Interleukin-1; Leukemia; Minor Histocompatibility Antigens; Proteins; Proto-Oncogene Proteins c-bcl-2; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1997 |
Dexamethasone potently enhances phorbol ester-induced IL-1beta gene expression and nuclear factor NF-kappaB activation.
Topics: Anti-Inflammatory Agents; Carcinogens; Dexamethasone; Drug Synergism; Gene Expression Regulation, Neoplastic; Humans; Interleukin-1; Leukemia; NF-kappa B; Tetradecanoylphorbol Acetate; Transcriptional Activation; Tumor Cells, Cultured | 1997 |
Protein kinase C is not necessary for transforming growth factor beta-induced growth-arrest in leukemia cell lines.
Topics: Calcitriol; Cell Differentiation; Cell Division; Cytokines; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Granulocyte Colony-Stimulating Factor; HL-60 Cells; Humans; Indoles; Isoenzymes; Jurkat Cells; Kinetics; Leukemia; Maleimides; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-alpha; Protein Kinase C-delta; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta; Tumor Cells, Cultured | 1997 |
Stage-specific expression of P2Y receptors, ecto-apyrase, and ecto-5'-nucleotidase in myeloid leukocytes.
Topics: 5'-Nucleotidase; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Antigens, CD; Apyrase; Bucladesine; Cell Differentiation; Cytosol; DNA Primers; Gene Expression Regulation, Neoplastic; HL-60 Cells; Humans; Leukemia; Leukocytes; Models, Biological; Polymerase Chain Reaction; Receptors, Purinergic P2; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Transcription, Genetic; Tumor Cells, Cultured; Uridine Triphosphate | 1997 |
Stimulation of p85/RING3 kinase in multiple organs after systemic administration of mitogens into mice.
Topics: Animals; Chromosomal Proteins, Non-Histone; Enzyme Activation; Epidermal Growth Factor; Gene Expression Regulation, Enzymologic; Humans; Interleukin-1; Kidney; Leukemia; Leukocytes; Liver; Lung; Mice; Myocardium; Organ Specificity; Protein Serine-Threonine Kinases; Tetradecanoylphorbol Acetate; Transcription Factors | 1998 |
Synthesis, storage, and release of vascular endothelial growth factor/vascular permeability factor (VEGF/VPF) by human mast cells: implications for the biological significance of VEGF206.
Topics: Blotting, Western; Calcimycin; Culture Media, Conditioned; Endothelial Growth Factors; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Humans; Leukemia; Lymphokines; Mast Cells; Microscopy, Immunoelectron; Polymerase Chain Reaction; Skin; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1998 |
Different effects of an oligonucleotide uptake stimulating protein on leukemic cells in their primitive and differentiated state.
Topics: Biological Transport; Cell Differentiation; Cell Division; Cytarabine; DNA-Binding Proteins; Fungal Proteins; Gene Transfer Techniques; Granulocytes; HL-60 Cells; Humans; Hydroxyurea; Leukemia; Leukocytes, Mononuclear; Oligodeoxyribonucleotides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1998 |
Aromatase expression and activity in the human leukaemic cell line FLG 29.1.
Topics: Androstenedione; Aromatase; Blotting, Southern; Cell Differentiation; Filaggrin Proteins; Gene Expression; Humans; Immunohistochemistry; Kinetics; Leukemia; Osteoclasts; Polymerase Chain Reaction; RNA-Directed DNA Polymerase; RNA, Messenger; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta; Tritium; Tumor Cells, Cultured; Water | 1998 |
Glucocorticoid-induced apoptosis and regulation of NF-kappaB activity in human leukemic T cells.
Topics: Apoptosis; Chromatin; Dexamethasone; DNA Fragmentation; Drug Resistance; Glucocorticoids; Humans; Leukemia; Mifepristone; Mutation; NF-kappa B; Receptors, Glucocorticoid; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1998 |
Phorbol 12-myristate 13-acetate stimulates lysophosphatidic acid secretion from ovarian and cervical cancer cells but not from breast or leukemia cells.
Topics: Breast Neoplasms; Carcinogens; Dose-Response Relationship, Drug; Female; Humans; Leukemia; Lysophospholipids; Ovarian Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Uterine Cervical Neoplasms | 1998 |
Downregulation of Wilms' tumor gene (WT1) is not a prerequisite for erythroid or megakaryocytic differentiation of the leukemic cell line K562.
Topics: Cell Differentiation; DNA-Binding Proteins; Erythroid Precursor Cells; Gene Expression; Gene Expression Regulation, Neoplastic; Hemin; Humans; K562 Cells; Leukemia; Megakaryocytes; Tetradecanoylphorbol Acetate; Transcription Factors; Transfection; WT1 Proteins | 1999 |
Inhibition of protein kinase C activator-mediated induction of p21CIP1 and p27KIP1 by deoxycytidine analogs in human leukemia cells: relationship to apoptosis and differentiation.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Bryostatins; Cell Cycle Proteins; Cell Differentiation; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclins; Cytarabine; Deoxycytidine; Drug Interactions; Enzyme Activation; Gemcitabine; Humans; Lactones; Leukemia; Macrolides; Microtubule-Associated Proteins; Mitogens; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Suppressor Proteins; U937 Cells | 1999 |
Modulation of histidine decarboxylase activity and cytokine synthesis in human leukemic cell lines: relationship with basophilic and/or megakaryocytic differentiation.
Topics: Basophils; Biomarkers; Cytokines; Enzyme Induction; Gene Expression Regulation, Leukemic; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoiesis; Hematopoietic Stem Cells; Histamine; Histidine Decarboxylase; HL-60 Cells; Humans; K562 Cells; Leukemia; Megakaryocytes; Neoplasm Proteins; Platelet Glycoprotein GPIIb-IIIa Complex; Platelet-Derived Growth Factor; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1999 |
Vitamin D analogs, 20-Epi-22-oxa-24a,26a,27a,-trihomo-1alpha,25(OH)2-vitamin D3, 1,24(OH)2-22-ene-24-cyclopropyl-vitamin D3 and 1alpha,25(OH)2-lumisterol3 prime NB4 leukemia cells for monocytic differentiation via nongenomic signaling pathways, involving
Topics: Biological Transport; Calcitriol; Calcium; Calpain; Cell Differentiation; Cell Nucleus; Cellular Senescence; Humans; Intracellular Membranes; Isoenzymes; Leukemia; Monocytes; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-delta; Receptors, Calcitriol; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vitamin D | 1999 |
Apoptosis of leukemic cells accompanies reduction in intracellular pH after targeted inhibition of the Na(+)/H(+) exchanger.
Topics: Adult; Amiloride; Animals; Antineoplastic Agents; Apoptosis; Humans; Hydrogen-Ion Concentration; K562 Cells; Leukemia; Lymphocytes; Mice; Mice, Inbred NOD; Mice, SCID; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate; Transplantation, Heterologous; Tumor Cells, Cultured | 2000 |
Induction and secretion of the chemokines interleukin-8 and monocyte chemotactic protein-1 in human immature leukemia cell lines.
Topics: Calcimycin; Carcinogens; Chemokine CCL2; Chemokines; Dexamethasone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Glucocorticoids; HL-60 Cells; Humans; Interleukin-8; Ionophores; Leukemia; Protein Biosynthesis; Staurosporine; Tetradecanoylphorbol Acetate; Thapsigargin; Transcription, Genetic; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2000 |
Differential regulation of vitamin D receptor expression in distinct leukemic cell lines upon phorbol ester-induced growth arrest.
Topics: Antibodies, Monoclonal; Carcinogens; Cell Differentiation; Down-Regulation; Fluorescent Antibody Technique; Gene Expression Regulation, Neoplastic; Growth Inhibitors; HL-60 Cells; Humans; K562 Cells; Leukemia; Phenotype; Receptors, Calcitriol; RNA; Tetradecanoylphorbol Acetate; U937 Cells | 2000 |
Failure to induce inhibition of cyclin A and up-regulation of p21 expression in phorbol ester-resistant U937 cells by phorbol ester.
Topics: Blotting, Western; Cell Count; Cyclin A; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinases; Cyclins; Down-Regulation; Enzyme Inhibitors; Flow Cytometry; G1 Phase; Gene Expression Regulation, Neoplastic; Humans; Leukemia; Phosphorylation; Precipitin Tests; Protein Kinase C; Tetradecanoylphorbol Acetate; U937 Cells; Up-Regulation | 2000 |
C-type natriuretic peptide is synthesized and secreted from leukemia cell lines, peripheral blood cells, and peritoneal macrophages.
Topics: Animals; Blood Cells; Cell Differentiation; Dexamethasone; HL-60 Cells; Humans; Interferon-gamma; Interleukin-1; Leukemia; Lipopolysaccharides; Macrophages, Peritoneal; Mice; Mice, Inbred C3H; Monocytes; Natriuretic Peptide, C-Type; Neoplasm Proteins; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta; Tretinoin; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2001 |
Mitochondria-targeting drugs arsenic trioxide and lonidamine bypass the resistance of TPA-differentiated leukemic cells to apoptosis.
Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Caspases; Cell Differentiation; Cell-Free System; Drug Resistance; Etoposide; Humans; Indazoles; Leukemia; Mitochondria; Oxides; Proto-Oncogene Proteins c-bcl-2; Tetradecanoylphorbol Acetate; U937 Cells | 2001 |
Differential effects of the MDR1 (multidrug resistance) gene-activating agents on protein kinase C: evidence for redundancy of mechanisms of acquired MDR in leukemia cells.
Topics: Ceramides; Cytarabine; Drug Resistance, Multiple; Enzyme Activation; Gene Expression Regulation; Genes, MDR; Humans; Leukemia; Protein Kinase C; Second Messenger Systems; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Up-Regulation | 2000 |
ASH2L: alternative splicing and downregulation during induced megakaryocytic differentiation of multipotential leukemia cell lines.
Topics: Alternative Splicing; Amino Acid Sequence; Animals; Base Sequence; Blotting, Northern; Cell Differentiation; DNA-Binding Proteins; Down-Regulation; Drosophila; Erythropoiesis; Fetus; Hematopoiesis; Hemin; Humans; Leukemia; Megakaryocytes; Molecular Sequence Data; Nuclear Proteins; Protein Isoforms; Sequence Alignment; Tetradecanoylphorbol Acetate; Transcription Factors; Tumor Cells, Cultured; Zinc Fingers | 2001 |
Sphingosine 1-phosphate antagonizes apoptosis of human leukemia cells by inhibiting release of cytochrome c and Smac/DIABLO from mitochondria.
Topics: Apoptosis; Apoptosis Regulatory Proteins; Carrier Proteins; Ceramides; Culture Media, Serum-Free; Cytochrome c Group; HL-60 Cells; Humans; Intracellular Signaling Peptides and Proteins; Jurkat Cells; Leukemia; Lysophospholipids; Mitochondria; Mitochondrial Proteins; Protein Transport; Receptors, Tumor Necrosis Factor; Sphingosine; Tetradecanoylphorbol Acetate; U937 Cells | 2001 |
The novel triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid (CDDO) potently enhances apoptosis induced by tumor necrosis factor in human leukemia cells.
Topics: Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Carcinogens; Caspase 3; Caspase 8; Caspase 9; Caspases; Cell Nucleus; Chromatin; Cytochrome c Group; Cytosol; DNA-Binding Proteins; Dose-Response Relationship, Drug; Enzyme Activation; Gene Expression Regulation; Humans; I-kappa B Proteins; Immunoblotting; JNK Mitogen-Activated Protein Kinases; Leukemia; MAP Kinase Kinase 4; Mitochondria; Mitogen-Activated Protein Kinase Kinases; NF-kappa B; NF-KappaB Inhibitor alpha; Nitric Oxide; Oleanolic Acid; Protein Transport; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2002 |
Specific PAF antagonist WEB-2086 induces terminal differentiation of murine and human leukemia cells.
Topics: Animals; Antineoplastic Agents; Azepines; Cell Differentiation; Cell Division; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Histones; HL-60 Cells; Humans; K562 Cells; Kinetics; Leukemia; Leukemia, Erythroblastic, Acute; Mice; Phospholipid Ethers; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Triazoles; Tumor Cells, Cultured | 2002 |
Altered lipid microviscosity in lymphoblastoid cells treated with 12-O-tetradecanoyl phorbol 13-acetate, a tumor promoter.
Topics: Animals; Cell Line; Cells, Cultured; Cholesterol; Humans; Kinetics; Leukemia; Leukemia L1210; Lipid Metabolism; Liposomes; Lymphocytes; Mice; Phorbols; Phospholipids; Spectrometry, Fluorescence; Tetradecanoylphorbol Acetate; Viscosity | 1979 |
Mutagenic specificity of oxygen radicals produced by human leukemia cells.
Topics: DNA, Bacterial; DNA, Single-Stranded; Escherichia coli; Humans; Hydrogen Peroxide; Leukemia; Mutagenicity Tests; Superoxides; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1992 |
Inhibition of protein kinase C results in decreased expression of bovine leukemia virus.
Topics: Animals; B-Lymphocytes; Cattle; Cattle Diseases; Cells, Cultured; Enzyme Activation; Female; Leukemia; Leukemia Virus, Bovine; Leukocytes, Mononuclear; Lipopolysaccharides; Lymphocyte Activation; Protein Kinase C; Tetradecanoylphorbol Acetate; Viral Envelope Proteins; Viral Proteins; Virus Replication | 1992 |
Affinity-purified c-Jun amino-terminal protein kinase requires serine/threonine phosphorylation for activity.
Topics: Cell Line; Chromatography, Affinity; Glutathione Transferase; Humans; Kinetics; Leukemia; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinases; Protein Phosphatase 2; Proto-Oncogene Proteins c-jun; Recombinant Fusion Proteins; Serine; Substrate Specificity; Tetradecanoylphorbol Acetate; Threonine | 1992 |
Augmentation of retinoic acid-induced granulocytic differentiation in HL-60 leukemia cells by serine/threonine protein phosphatase inhibitors.
Topics: Cell Adhesion; Cell Differentiation; Chromatography, Agarose; Ethers, Cyclic; Granulocytes; Humans; Leukemia; Macrophages; Marine Toxins; Okadaic Acid; Oxazoles; Phosphoprotein Phosphatases; Phosphorylation; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1992 |
Dolastatin 10 and dolastatin 15: effects of two natural peptides on growth and differentiation of leukemia cells.
Topics: Antineoplastic Agents; Bryostatins; Cell Differentiation; Cell Division; Depsipeptides; Humans; In Vitro Techniques; Lactones; Leukemia; Macrolides; Oligopeptides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
Bistratene A: a novel compound causing changes in protein phosphorylation patterns in human leukemia cells.
Topics: Acetamides; Antineoplastic Agents; Bryostatins; Ethers, Cyclic; Humans; Lactones; Leukemia; Macrolides; Neoplasm Proteins; Phosphorylation; Pyrans; Spiro Compounds; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
Expression of the serglycin gene in human leukemic cell lines.
Topics: Blotting, Northern; Dimethyl Sulfoxide; Gene Expression; Humans; In Vitro Techniques; Leukemia; Proteoglycans; RNA, Messenger; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured; Vesicular Transport Proteins | 1992 |
Regulation of myeloid-specific calcium binding protein synthesis by cytosolic protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Blotting, Northern; Calcitriol; Calcium-Binding Proteins; Calgranulin A; Calgranulin B; Cell Differentiation; Cytosol; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Humans; Isoquinolines; Leukemia; Mice; Mice, Inbred BALB C; Piperazines; Protein Kinase C; RNA, Messenger; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta; Tretinoin; Tumor Cells, Cultured | 1992 |
Activation of human leukemia protein kinase C by tumor promoters and its inhibition by N-trifluoroacetyladriamycin-14-valerate (AD 32).
Topics: Binding, Competitive; Cell Membrane; Doxorubicin; Drug Interactions; Enzyme Activation; Humans; Kinetics; Leukemia; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Binding; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
K562 leukemia cells express P2T (adenosine diphosphate) purinergic receptors.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Alkaloids; Calcium; Fura-2; Leukemia; Protein Kinase C; Receptors, Purinergic; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
B-myb antisense oligonucleotides inhibit proliferation of human hematopoietic cell lines.
Topics: B-Lymphocytes; Base Sequence; Cell Division; Cell Line; DNA Replication; Dose-Response Relationship, Drug; Gene Expression; Humans; Kinetics; Leukemia; Molecular Sequence Data; Oligonucleotides, Antisense; Oncogenes; Polymerase Chain Reaction; Tetradecanoylphorbol Acetate; Thymidine | 1992 |
Mitotic arrest and enhanced nuclear protein phosphorylation in human leukemia K562 cells by okadaic acid, a potent protein phosphatase inhibitor and tumor promoter.
Topics: Autoradiography; Carcinogens; Colchicine; Electrophoresis, Polyacrylamide Gel; Ethers, Cyclic; Humans; Leukemia; Mitosis; Nuclear Proteins; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
The regulation of TNF receptor mRNA synthesis, membrane expression, and release by PMA- and LPS-stimulated human monocytic THP-1 cells in vitro.
Topics: Base Sequence; Cell Membrane; Cells, Cultured; Gene Expression Regulation; Humans; Leukemia; Lipopolysaccharides; Molecular Sequence Data; Monocytes; Receptors, Cell Surface; Receptors, Tumor Necrosis Factor; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1991 |
The effect of staurosporine on drug-induced, topoisomerase II-mediated DNA cleavage in human leukemia cells.
Topics: Alkaloids; Amsacrine; Cell Line; DNA Damage; DNA Topoisomerases, Type II; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Interactions; Etoposide; Humans; Leukemia; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured | 1991 |
Regulation of leukocyte adhesion molecule-1 (TQ1, Leu-8) expression and shedding by normal and malignant cells.
Topics: Cell Adhesion Molecules; Down-Regulation; Fluorescent Antibody Technique; Humans; L-Selectin; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukocytes, Mononuclear; Precipitin Tests; Receptors, Leukocyte-Adhesion; Tetradecanoylphorbol Acetate | 1991 |
Characterization of the 3',5'-cyclic adenosine monophosphate-mediated regulation of IL2 production by T cells and Jurkat cells.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adult; Cell Line; Cholera Toxin; Cyclic AMP; Dinoprostone; Humans; Interleukin-2; Leukemia; Phosphatidylinositols; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
Clinical significance of CD7-positive stem cell leukemia. A distinct subtype of mixed lineage leukemia.
Topics: Acute Disease; Adolescent; Antigens, CD; Antigens, CD7; Antigens, Differentiation, T-Lymphocyte; Cell Transformation, Neoplastic; Child; Child, Preschool; DNA, Neoplasm; Female; Gene Rearrangement; Genotype; Humans; Immunophenotyping; Infant; Karyotyping; Leukemia; Male; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1991 |
Identification of a gene, MLL, that spans the breakpoint in 11q23 translocations associated with human leukemias.
Topics: Adult; Blotting, Northern; Blotting, Southern; Cell Line; Child, Preschool; Chromosome Banding; Chromosomes, Human, Pair 11; Cloning, Molecular; DNA, Neoplasm; Female; Gene Expression; Genes; Humans; Karyotyping; Leukemia; Male; Middle Aged; Poly A; Restriction Mapping; RNA; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Translocation, Genetic | 1991 |
Microfilament-disrupting agents prevent the formation of apoptotic bodies in tumor cells undergoing apoptosis.
Topics: Actin Cytoskeleton; Aphidicolin; Camptothecin; Cell Death; Cell Line; Cell Survival; Cytochalasin B; Humans; Ionomycin; Kinetics; Leukemia; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 1992 |
Differentiation-associated expression of prostaglandin H and thromboxane A synthases in monocytoid leukemia cell lines.
Topics: Arachidonic Acid; Calcimycin; Cell Differentiation; Granulocytes; Humans; Leukemia; Lipoxygenase; Monocytes; Prostaglandin-Endoperoxide Synthases; Tetradecanoylphorbol Acetate; Thromboxane-A Synthase; Tretinoin; Tumor Cells, Cultured | 1991 |
Rapid turnover of low density lipoprotein receptor in human monocytic THP-1 cells.
Topics: Cell Differentiation; Gene Expression; Half-Life; Humans; Leukemia; Macrophages; Monocytes; Receptors, LDL; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
dsDNA-stimulated phosphorylation of a 72-kDa nucleoprotein accompanies PMA-induced HL-60 leukemic cell differentiation.
Topics: Alkaloids; Cell Differentiation; Deoxyribonucleases; DNA; Humans; Leukemia; Nuclear Proteins; Phosphorylation; Protein Kinase C; Protein Kinases; Ribonucleases; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
Identification of a 38-kDa protein (p38) in HL-60 leukemic cells as a truncated actin.
Topics: Actins; Amino Acid Sequence; Blotting, Western; Cell Division; Electrophoresis, Polyacrylamide Gel; Humans; Interferon-gamma; Leukemia; Molecular Sequence Data; Molecular Weight; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
PLC gamma 1, a possible mediator of T cell receptor function.
Topics: Antigens, Differentiation, T-Lymphocyte; Blotting, Western; CD3 Complex; Colforsin; Enzyme Activation; Humans; Leukemia; Phosphorylation; Precipitin Tests; Protein Kinase C; Protein Kinases; Receptors, Antigen, T-Cell; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Type C Phospholipases; Tyrosine | 1991 |
Thymic origin of some natural killer cells: clonal proliferation of human CD3-16+ cells from CD3-4-8- thymocyte precursors requires the presence of H9 leukemic cells.
Topics: Antigens, CD; Antigens, Differentiation; Cell Differentiation; Cell Division; Cells, Cultured; Clone Cells; Cytotoxicity Tests, Immunologic; Humans; Immunophenotyping; Interferon-gamma; Interleukin-2; Killer Cells, Natural; Leukemia; Lymphocyte Activation; Phytohemagglutinins; Receptors, Fc; Receptors, IgG; Tetradecanoylphorbol Acetate; Thymus Gland; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1991 |
Changes in the kinetics of inositol transport during TPA-induced differentiation of HL60 cells towards monocytes.
Topics: Biological Transport; Cell Differentiation; Humans; Inositol; Kinetics; Leukemia; Monocytes; Phagocytosis; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
Enhanced poly ADP-ribosylation in human leukemia lymphocytes and ovarian cancers.
Topics: Adolescent; Adult; Biomarkers, Tumor; Carcinogens; Cell Division; Diterpenes; DNA Damage; Female; Humans; Kinetics; Leukemia; Lymphocytes; Middle Aged; NAD; Ovarian Neoplasms; Poly(ADP-ribose) Polymerases; Terpenes; Tetradecanoylphorbol Acetate | 1991 |
Differential expression of two classes of lck transcripts upon phorbol ester treatment of human leukemic T cells.
Topics: Cell Line; Cells, Cultured; Colonic Neoplasms; Gene Expression Regulation, Neoplastic; HeLa Cells; Humans; Kinetics; Leukemia; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Oncogene Proteins, Viral; Oncogenes; Polymerase Chain Reaction; Promoter Regions, Genetic; Protein-Tyrosine Kinases; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1991 |
Elevated expression of proto-oncogenes during interleukin-5-induced growth and differentiation of murine B lineage cells.
Topics: Animals; Cell Transformation, Neoplastic; Chronic Disease; Female; Gene Expression Regulation; Immunoglobulin M; Interleukin-5; Kinetics; Leukemia; Mice; Mice, Inbred Strains; Proto-Oncogene Proteins c-myc; Proto-Oncogenes; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Inhibition of phorbol ester-induced monocytic differentiation and c-fms gene expression by dexamethasone: potential involvement of arachidonic acid metabolites.
Topics: Arachidonic Acids; Cell Transformation, Neoplastic; Dexamethasone; Gene Expression Regulation, Leukemic; Humans; Leukemia; Monocytes; Phenotype; Proto-Oncogene Proteins; Receptor, Macrophage Colony-Stimulating Factor; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Protein kinase C-independent activation of nuclear factor kappa B by tumor necrosis factor.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Base Sequence; Binding Sites; Cell Line; DNA-Binding Proteins; DNA, Viral; Down-Regulation; Enhancer Elements, Genetic; Enzyme Activation; H-2 Antigens; HIV-1; Humans; Isoquinolines; Leukemia; Molecular Sequence Data; NF-kappa B; Phorbol 12,13-Dibutyrate; Piperazines; Promoter Regions, Genetic; Protein Kinase C; Recombinant Proteins; Staurosporine; Tetradecanoylphorbol Acetate; Transcription Factors; Tumor Necrosis Factor-alpha | 1990 |
Synergistic induction of interleukin 2 receptor (TAC) expression on YT cells by simultaneous activation of distinct signal transduction pathways.
Topics: Adenylyl Cyclases; Alkaloids; Colforsin; Humans; Interleukin-1; Killer Cells, Natural; Leukemia; Protein Kinase C; Receptors, Interleukin-2; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1990 |
Selective post-transcriptional down-regulation of protein kinase C isoenzymes in leukemic T cells chronically treated with phorbol ester.
Topics: Amino Acid Sequence; Animals; Cattle; Cell Line; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Immunoblotting; Isoenzymes; Kinetics; Leukemia; Molecular Sequence Data; Molecular Weight; Oligonucleotide Probes; Peptide Fragments; Protein Biosynthesis; Protein Kinase C; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 1990 |
P47 phosphoprotein of blood platelets (pleckstrin) is a major target for phorbol ester-induced protein phosphorylation in intact platelets, granulocytes, lymphocytes, monocytes and cultured leukaemic cells: absence of P47 in non-haematopoietic cells.
Topics: Blood Platelets; Blood Proteins; Blotting, Western; Cells, Cultured; Electrophoresis, Polyacrylamide Gel; Granulocytes; Humans; Leukemia; Leukocytes; Lymphocytes; Monocytes; Phosphoproteins; Phosphorylation; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Expression of the thymosin beta 4 gene during differentiation of hematopoietic cells.
Topics: Adult; Cell Differentiation; Cell Line; Female; Gene Expression Regulation; Hematopoietic Stem Cells; Humans; Kinetics; Leukemia; Leukocytes; Male; Middle Aged; Reference Values; RNA, Messenger; Tetradecanoylphorbol Acetate; Thymosin; Transcription, Genetic | 1990 |
Tissue distribution and biochemical and functional properties of Tp55 (CD27), a novel T cell differentiation antigen.
Topics: Antibodies, Monoclonal; Antigens, Differentiation, T-Lymphocyte; Antigens, Surface; CD3 Complex; Cell Line; Clone Cells; Epitopes; Hematopoietic Stem Cells; Humans; Leukemia; Lymph Nodes; Lymphocyte Activation; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymus Gland | 1987 |
Molecular basis for the aberrant expression of T cell antigens in postthymic T cell malignancies.
Topics: Antigens, Differentiation, T-Lymphocyte; Cell Survival; Chromosome Deletion; Genes; Histiocytes; Humans; Leukemia; Nucleic Acid Hybridization; Phenotype; Receptors, Immunologic; Recombination, Genetic; RNA; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymus Gland; Transcription, Genetic; Tumor Cells, Cultured | 1988 |
Alteration of p60c-src expression in human leukemia-lymphoma cells correlated with induced differentiation.
Topics: Cell Differentiation; Cell Line; Flow Cytometry; Humans; Leukemia; Lymphoma; Monocytes; Phagocytosis; Protein Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins pp60(c-src); Proto-Oncogenes; Reference Values; Tetradecanoylphorbol Acetate | 1988 |
[Human oncogene expression in the normal state and in various blood system diseases].
Topics: Antineoplastic Agents; Gene Expression Regulation, Leukemic; Humans; Leukemia; Leukemia, Myeloid, Acute; Leukocytes, Mononuclear; Nucleic Acid Hybridization; Oncogenes; Pancytopenia; Phytohemagglutinins; RNA; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1989 |
Expression of thromboxane A2 receptor in cultured human erythroleukemia cells and its induction by 12-O-tetradecanoylphorbol-13-acetate.
Topics: Animals; Bridged Bicyclo Compounds; Dactinomycin; Fatty Acids, Monounsaturated; Humans; Iodine Radioisotopes; Kinetics; Leukemia; Leukemia, Erythroblastic, Acute; Mice; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins H; Receptors, Prostaglandin; Receptors, Thromboxane; Tetradecanoylphorbol Acetate; Thromboxane A2; Tumor Cells, Cultured | 1989 |
Studies of protein kinase C in the rat basophilic leukemia (RBL-2H3) cell reveal that antigen-induced signals are not mimicked by the actions of phorbol myristate acetate and Ca2+ ionophore.
Topics: Alkaloids; Animals; Antigens; Basophils; Calcimycin; Cell Line; Enzyme Activation; Kinetics; Leukemia; Phosphatidylinositols; Protein Kinase C; Rats; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate | 1989 |
Triggering of neutrophil cytotoxicity against an antibody-coated tumour target by TPA.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Antibodies, Monoclonal; Antibody-Dependent Cell Cytotoxicity; Cell Degranulation; Egtazic Acid; Humans; Isoquinolines; Leukemia; Muramidase; Neutrophils; Piperazines; Superoxides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
Activation of HIV gene expression during monocyte differentiation by induction of NF-kappa B.
Topics: Cell Differentiation; Chloramphenicol O-Acetyltransferase; DNA, Viral; Enhancer Elements, Genetic; Gene Expression Regulation; HIV; Leukemia; Monocytes; NF-kappa B; Phorbol 12,13-Dibutyrate; Plasmids; Tetradecanoylphorbol Acetate; Transcription Factors; Transfection; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1989 |
Effects of inducers of differentiation on protein kinase C and CMP-N-acetylneuraminic acid:lactosylceramide sialyltransferase activities of HL-60 leukemia cells.
Topics: Cell Differentiation; Cell Division; Dimethyl Sulfoxide; Gangliosides; Glycosphingolipids; Humans; Leukemia; Phagocytosis; Protein Kinase C; Sialyltransferases; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
An autocrine growth factor constitutively produced by a human lymphoblastoid B-cell line is serologically related to lymphotoxin (TNF-beta).
Topics: Cell Division; Cell Line; Humans; Leukemia; Lymphotoxin-alpha; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
Study of differentiation of fresh human leukemic cells by low dose cytosine arabinoside (LD Ara-C) and 12-O-tetradecanoylphorbol-13-acetate (TPA).
Topics: Antigens, Neoplasm; Blast Crisis; Bone Marrow; Cell Adhesion Molecules; Cell Differentiation; Cytarabine; Glycoproteins; Humans; Leukemia; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
Scavenger receptor of human monocytic leukemia cell line (THP-1) and murine macrophages for nonenzymatically glycosylated proteins.
Topics: Animals; Blood Proteins; Cell Line; Endocytosis; Glycated Serum Proteins; Glycoproteins; Glycosylation; Humans; Kinetics; Leukemia; Membrane Proteins; Mice; Receptors, Immunologic; Receptors, Lipoprotein; Receptors, Scavenger; Scavenger Receptors, Class B; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
12-O-tetradecanoylphorbol-13-acetate induces the enhancer function of human T-cell leukemia virus type I.
Topics: Deltaretrovirus; Enhancer Elements, Genetic; Gene Expression Regulation; Humans; Leukemia; Regulatory Sequences, Nucleic Acid; Repetitive Sequences, Nucleic Acid; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1987 |
Induction of myeloperoxidase in five cases of acute unclassified leukaemia.
Topics: Acute Disease; Adult; Antigens, Differentiation; Antigens, Neoplasm; Cells, Cultured; Enzyme Induction; Female; Humans; Leukemia; Male; Microscopy, Electron; Middle Aged; Peroxidase; Tetradecanoylphorbol Acetate | 1988 |
Dipeptidyl peptidase IV activity in cells of T-lymphoid origin is decreased in cultures with 12-0-tetradecanoylphorbol-13-acetate (TPA).
Topics: Blood Cells; Cell Differentiation; Cells, Cultured; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Humans; Leukemia; Reference Values; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1987 |
In vitro study of translocation t(4;11) acute leukemia. Sequential range of phenotype.
Topics: Acute Disease; Cells, Cultured; Humans; Leukemia; Phenotype; Tetradecanoylphorbol Acetate; Translocation, Genetic | 1989 |
Cremophor EL, a widely used parenteral vehicle, is a potent inhibitor of protein kinase C.
Topics: Binding, Competitive; Cell Line; DNA Polymerase II; Drug Carriers; Glycerol; Humans; Kinetics; Leukemia; Phorbol 12,13-Dibutyrate; Protein Binding; Protein Kinase C; Protein Kinases; RNA Polymerase II; Solvents; Tetradecanoylphorbol Acetate | 1989 |
Surface functions during mitosis in rat basophilic leukemia cells.
Topics: Animals; Basophils; Cell Membrane; Coated Pits, Cell-Membrane; Endocytosis; Fluorescent Antibody Technique; Immunoglobulin E; Leukemia; Membrane Fluidity; Microscopy, Electron; Mitosis; Pinocytosis; Protein Binding; Rats; Receptors, Fc; Receptors, IgE; Receptors, Immunologic; Serotonin; Tetradecanoylphorbol Acetate | 1985 |
Phorbol 12-myristate 13-acetate induces surface expression of T3 on human immature T cell lines with and without concomitant expression of the T cell antigen receptor complex.
Topics: Antibodies, Monoclonal; Antigens, Surface; CD3 Complex; Cell Differentiation; Cell Line; Cell Membrane; Cytoplasm; Gene Expression Regulation; Humans; In Vitro Techniques; Kinetics; Leukemia; Molecular Weight; Receptors, Antigen, T-Cell; Tetradecanoylphorbol Acetate | 1987 |
Production of tumor necrosis factor/cachectin by human T cell lines and peripheral blood T lymphocytes stimulated by phorbol myristate acetate and anti-CD3 antibody.
Topics: Antibodies, Monoclonal; Antigens, Differentiation, T-Lymphocyte; Calcimycin; CD3 Complex; Cell Line; Gene Expression Regulation; Humans; Leukemia; Lymphotoxin-alpha; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1988 |
Translocation of protein kinase C in rat basophilic leukemic cells induced by phorbol ester or by aggregation of IgE receptors.
Topics: Animals; Basophils; Biological Transport; Calcimycin; Calcium; Cell Line; Exocytosis; Extracellular Space; Haptens; Immunoglobulin E; Leukemia; Protein Kinase C; Rats; Receptor Aggregation; Receptors, Fc; Receptors, IgE; Tetradecanoylphorbol Acetate | 1988 |
Protein kinase activation and the immunosuppressant cyclosporine.
Topics: Animals; Cell Line; Cyclic AMP; Cyclosporins; Enzyme Activation; Enzyme Induction; Leukemia; Lymphocyte Activation; Mice; Ornithine Decarboxylase; Protein Kinase C; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1986 |
Loss and reappearance of transferrin receptors in human leukemic cell lines.
Topics: Butyrates; Butyric Acid; Cell Differentiation; Cell Line; Dimethyl Sulfoxide; DNA Replication; Heme; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Receptors, Cell Surface; Receptors, Transferrin; Tetradecanoylphorbol Acetate; Transferrin; Tretinoin | 1986 |
Differentiation and the multiple drug resistance phenotype in human leukemic cells.
Topics: Antibodies, Monoclonal; Antigens, Differentiation, T-Lymphocyte; Antigens, Neoplasm; Antigens, Surface; Cell Differentiation; Drug Resistance; Glycoproteins; Humans; Leukemia; Neoplasm Proteins; Receptors, Cell Surface; Receptors, Transferrin; Tetradecanoylphorbol Acetate | 1986 |
The probable role of superoxide produced by blast cells in leukaemic cutaneous spreading.
Topics: Acute Disease; Adult; Aged; Female; Humans; In Vitro Techniques; Leukemia; Leukemia, Myeloid, Acute; Male; Middle Aged; Skin Neoplasms; Superoxides; Tetradecanoylphorbol Acetate | 1986 |
Induction of early myeloperoxidase in acute unclassified leukemia.
Topics: Acute Disease; Antigens, Surface; Cells, Cultured; Fluorescent Antibody Technique; Humans; Leukemia; Lymphocytes; Peroxidase; Tetradecanoylphorbol Acetate | 1987 |
Cellular distribution of a B-cell specific surface antigen (gp54) detected by a monoclonal antibody (anti-BL4).
Topics: Animals; Antibodies, Monoclonal; Antigens, Differentiation, B-Lymphocyte; Antigens, Surface; B-Lymphocytes; Cell Differentiation; Glycoproteins; Humans; Leukemia; Lymphoma; Mice; Mice, Inbred BALB C; Tetradecanoylphorbol Acetate | 1986 |
Human acute unclassified leukemia with a unique t(4;17) chromosomal translocation expresses T lymphoid and myeloid surface antigens after in vitro culture.
Topics: Antigens, Neoplasm; Antigens, Surface; Cell Differentiation; Cells, Cultured; Chromosomes, Human, Pair 17; Chromosomes, Human, Pair 4; Genes; Humans; Immunoglobulin Heavy Chains; Karyotyping; Leukemia; Lymphocytes, Null; Male; Middle Aged; Peroxidases; Receptors, Antigen, T-Cell; Receptors, Immunologic; Receptors, Interleukin-2; Recombination, Genetic; Tetradecanoylphorbol Acetate; Translocation, Genetic | 1987 |
Characterization of interleukin-2 receptors expressed on acute leukemic B cells.
Topics: Acute Disease; B-Lymphocytes; Cell Differentiation; Genes; Humans; Immunoglobulins; Interleukin-2; Leukemia; Male; Middle Aged; Phenotype; Receptors, Immunologic; Receptors, Interleukin-2; Recombinant Proteins; Tetradecanoylphorbol Acetate | 1987 |
Expression of c-fos in human normal and neoplastic monocyte-macrophage differentiation.
Topics: Calcitriol; Cell Differentiation; Gene Expression Regulation; Humans; Leukemia; Leukemia, Erythroblastic, Acute; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Macrophages; Monocytes; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1987 |
Clinical application of phorbol diester-induced leukemic cell differentiation for the definite diagnosis of acute leukemias.
Topics: Acute Disease; Adolescent; Adult; Cell Differentiation; Cell Transformation, Neoplastic; Diagnosis, Differential; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Middle Aged; Tetradecanoylphorbol Acetate | 1988 |
Expression of the human T-cell-specific tyrosine kinase YT16 (lck) message in leukemic T-cell lines.
Topics: Antibodies, Monoclonal; Calcium; Cell Line; Humans; Interleukin-2; Leukemia; Phytohemagglutinins; Protein-Tyrosine Kinases; Recombinant Proteins; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1988 |
Lectin interactions with the Jurkat leukemic T-cell line: quantitative binding studies and interleukin-2 production.
Topics: Binding Sites; Humans; Interleukin-2; Iodine Radioisotopes; Lectins; Leukemia; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1988 |
Effect of tumor promoter 12-O-tetradecanoyl-phorbol 13-acetate on CD 7 expression by T lineage cells.
Topics: Antibodies, Monoclonal; Antigens, Differentiation, T-Lymphocyte; Depression, Chemical; Diglycerides; Ethers; Gene Expression Regulation; Humans; Ionomycin; Leukemia; Phosphatidylinositols; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1988 |
In vitro induction of myeloid surface markers in a rare case of acute leukemia.
Topics: Acute Disease; Aged; Antibodies, Monoclonal; Antigens, Neoplasm; Antigens, Surface; Blast Crisis; Cells, Cultured; Flow Cytometry; Fluorescent Antibody Technique; Humans; Hybridization, Genetic; Leukemia; Leukemia, Myeloid, Acute; Lewis X Antigen; Lymphocytes; Male; Neuraminidase; Phenotype; Tetradecanoylphorbol Acetate | 1987 |
Differential down-regulation of protein kinase C subspecies in KM3 cells.
Topics: Cell Compartmentation; Humans; Leukemia; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1988 |
[The action mechanisms of 12-0-tetradecanoylphorbol-13-acetate (TPA) and combined effects with TPA and fibroblast growth factor on the proliferation of leukemic myeloid progenitor cells].
Topics: Bone Marrow Cells; Cell Transformation, Neoplastic; Cells, Cultured; Fibroblast Growth Factors; Hematopoiesis; Hematopoietic Stem Cells; Humans; Leukemia; Tetradecanoylphorbol Acetate | 1987 |
Purification and characterization of erythroid differentiation factor (EDF) isolated from human leukemia cell line THP-1.
Topics: Activins; Amino Acid Sequence; Animals; Cell Differentiation; Cell Line; Friend murine leukemia virus; Humans; Inhibins; Leukemia; Leukemia, Erythroblastic, Acute; Leukemia, Experimental; Macromolecular Substances; Mice; Molecular Weight; Neoplasm Proteins; Peptide Fragments; Tetradecanoylphorbol Acetate | 1987 |
Occurrence of particular isoenzymes in fresh and cultured leukemia-lymphoma cells. I. Tartrate-resistant acid phosphatase isoenzyme.
Topics: Acid Phosphatase; B-Lymphocytes; Cell Differentiation; Cell Line; Humans; Isoelectric Focusing; Isoenzymes; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Lymphoma; Monocytes; Tartrates; Tetradecanoylphorbol Acetate | 1986 |
Occurrence of particular isoenzymes in fresh and cultured leukemia-lymphoma cells. II. Hexosaminidase I isoenzyme.
Topics: Acetylglucosaminidase; B-Lymphocytes; Cell Differentiation; Cell Line; Hexosaminidases; Humans; Isoelectric Focusing; Isoenzymes; Leukemia; Lymphoma; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1986 |
Secretory leukemic B cells express T cell markers in vitro. A phenomenon suppressed by TPA.
Topics: Antigens, Surface; B-Lymphocytes; Cell Differentiation; Humans; Immunoglobulin M; In Vitro Techniques; Isoenzymes; L-Lactate Dehydrogenase; Leukemia; Phorbols; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1986 |
Pre-B and non-T/non-B leukemia cell lines BV-173, KM-3, NALM-6, and REH: changes in isoenzyme profiles during induction of differentiation.
Topics: Acetylglucosaminidase; Acid Phosphatase; B-Lymphocytes; Carboxylesterase; Carboxylic Ester Hydrolases; Cell Cycle; Cell Differentiation; Cell Line; Cell Survival; Humans; Isoenzymes; L-Lactate Dehydrogenase; Leukemia; Lymphocytes; Tetradecanoylphorbol Acetate | 1986 |
Occurrence of particular isoenzymes in fresh and cultured leukemia-lymphoma cells. III. Esterase isoenzyme in monocytes.
Topics: B-Lymphocytes; Carboxylic Ester Hydrolases; Cell Differentiation; Cell Line; Enzyme Activation; Humans; Isoenzymes; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lymphoma; Monocytes; Naphthol AS D Esterase; Tetradecanoylphorbol Acetate | 1987 |
T-leukemia cell lines CCRF-CEM, HPB-ALL, JM and MOLT-4: changes in isoenzyme profiles during induction of differentiation.
Topics: Cell Aggregation; Cell Differentiation; Cell Division; Cell Line; Cell Survival; Isoenzymes; Leukemia; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1987 |
Human leukemic B cell activation: functional consequence of membrane IgM interaction with anti-IgM ligand is an alterable cell characteristic.
Topics: Antibodies, Anti-Idiotypic; Antigens, Neoplasm; Antigens, Surface; B-Lymphocytes; Cell Differentiation; Clone Cells; DNA; Humans; Immunoglobulin M; Leukemia; Ligands; Lymphocyte Activation; Receptors, Antigen, B-Cell; Solubility; Tetradecanoylphorbol Acetate | 1987 |
Signal requirement for interleukin-1-dependent interleukin 2 production by a human leukemia-derived HSB.2 subclone.
Topics: Calcium; Enzyme Activation; Ethers; Humans; Interleukin-1; Interleukin-2; Ionomycin; Leukemia; Lymphocyte Activation; Phosphatidylinositols; Phytohemagglutinins; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1987 |
Differential effects of phorbol esters on normal myeloid precursors and leukemic cells: basis for autologous bone marrow reconstitution in acute nonlymphocytic leukemia using phorbol ester-treated bone marrow from patients in remission.
Topics: Bone Marrow; Bone Marrow Cells; Bone Marrow Transplantation; Cell Cycle; Cell Differentiation; Cells, Cultured; Colony-Forming Units Assay; Combined Modality Therapy; Dose-Response Relationship, Drug; Freezing; Hematopoiesis; Humans; Karyotyping; Leukemia; Leukemia, Myeloid, Acute; Phorbols; Preservation, Biological; Tetradecanoylphorbol Acetate; Time Factors | 1986 |
Changes in thymidine kinase activity during differentiation of HL-60 leukemic cells.
Topics: Cell Differentiation; Cell Line; Leukemia; Tetradecanoylphorbol Acetate; Thymidine Kinase | 1987 |
Modification of luminol-dependent chemiluminescence reactivity of peripheral blood leukocytes from patients with lymphoreticular tumor, solid cancer, or healthy blood donors by interferon-alpha.
Topics: Adult; Aged; Aged, 80 and over; Female; Humans; In Vitro Techniques; Interferon Type I; Leukemia; Leukocytes; Luminescent Measurements; Luminol; Lymphoma; Male; Middle Aged; Neoplasms; Phagocytes; Tetradecanoylphorbol Acetate; Zymosan | 1987 |
[In vitro differentiation of hematologic malignant cells with phorbol myristate acetate].
Topics: Cell Differentiation; Cells, Cultured; Humans; Leukemia; Lymphocytes; Lymphoma; Tetradecanoylphorbol Acetate | 1987 |
[Use of the phorbol ester differentiation test in the classification of acute leukemia].
Topics: Acute Disease; Adolescent; Adult; Cell Transformation, Neoplastic; Child; Child, Preschool; Diagnosis, Differential; Female; Humans; Infant; Leukemia; Male; Middle Aged; Tetradecanoylphorbol Acetate | 1987 |
Expression of the c-fos gene during differentiation.
Topics: Calcitriol; Cell Differentiation; Cell Line; Humans; Leukemia; Macrophage Activation; Proto-Oncogenes; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1987 |
Phorbol ester (TPA)-induced surface membrane alterations in B-type hairy cell and lymphocytic leukemia cells.
Topics: Acute Disease; Cell Adhesion; Cell Membrane; Humans; Leukemia; Leukemia, Hairy Cell; Leukemia, Lymphoid; Leukocytes; Microscopy, Electron; Microscopy, Electron, Scanning; Microvilli; Tetradecanoylphorbol Acetate | 1986 |
A 93-kDa glycoprotein expressed on human cultured monocytes and dendritic reticulum cells defined by an anti-K562 monoclonal antibody.
Topics: Antibodies, Monoclonal; Cells, Cultured; Dendritic Cells; Glycoproteins; Humans; Leukemia; Molecular Weight; Monocytes; Tetradecanoylphorbol Acetate | 1986 |
Antileukemic agent alkyllysophospholipid regulates phosphorylation of distinct proteins in HL60 and K562 cells and differentiation of HL60 cells promoted by phorbol ester.
Topics: Antineoplastic Agents; Cell Differentiation; Cell Line; Electrophoresis, Polyacrylamide Gel; Humans; Isoelectric Focusing; Leukemia; Lysophospholipids; Phospholipids; Phosphoproteins; Phosphorylation; Tetradecanoylphorbol Acetate | 1987 |
Induction of cytoskeletal vimentin and actin gene expression by a tumor-promoting phorbol ester in the human leukemic cell line K562.
Topics: Actins; Cell Line; Cytoskeleton; DNA; Gene Expression Regulation; Humans; Leukemia; Methionine; Nucleic Acid Hybridization; Phorbols; Protein Biosynthesis; RNA, Messenger; Tetradecanoylphorbol Acetate; Vimentin | 1985 |
Cytochemical examinations of cultivated unclassified leukaemic cells.
Topics: Acute Disease; Cell Differentiation; Cell Division; Cells, Cultured; Esterases; Histocytochemistry; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Tetradecanoylphorbol Acetate | 1985 |
Analysis of human T lymphocyte activation in a T cell tumor model system.
Topics: Animals; Antibodies, Monoclonal; Disease Models, Animal; Galactose Oxidase; Humans; Leukemia; Lymphocyte Activation; Mice; Neuraminidase; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1985 |
Tpa-induced maturation in secretory human B-leukemic cells in vitro: DNA synthesis, antigenic changes, and immunoglobulin secretion.
Topics: Aged; Antigens, Surface; B-Lymphocytes; Cell Cycle; Cell Differentiation; Cell Division; Cells, Cultured; DNA; Growth Substances; Humans; Immunoglobulin M; Immunoglobulins; Leukemia; Male; Neoplastic Stem Cells; Phorbols; Tetradecanoylphorbol Acetate | 1985 |
Suppression of phorbol myristate acetate-triggering of macrophage H2O2 release by sarcoma 180 originating factor.
Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Extracts; Female; Hydrogen Peroxide; Leukemia; Macrophage Activation; Macrophage Migration-Inhibitory Factors; Macrophages; Mice; Mice, Inbred AKR; Mice, Inbred C3H; Neoplasm Proteins; Phagocytosis; Sarcoma 180; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1985 |
Human acute leukemia cell line with the t(4;11) chromosomal rearrangement exhibits B lineage and monocytic characteristics.
Topics: Adult; Antigens, Differentiation, B-Lymphocyte; Antigens, Neoplasm; Antigens, Surface; B-Lymphocytes; Cell Line; Cell Transformation, Neoplastic; Chromosome Aberrations; Chromosome Disorders; Clone Cells; Female; Histocytochemistry; Humans; Immunoglobulins; Karyotyping; Leukemia; Monocytes; Tetradecanoylphorbol Acetate | 1985 |
HLA class-I and class-II antigen expression by human leukemic K562 cells and by Burkitt-K562 hybrids: modulation by differentiation inducers and interferon.
Topics: Burkitt Lymphoma; Butyrates; Butyric Acid; Cell Differentiation; Cell Line; Gene Expression Regulation; HLA Antigens; Humans; Hybrid Cells; Interferon Type I; Interferon-gamma; Leukemia; Lyngbya Toxins; Phenotype; Tetradecanoylphorbol Acetate | 1985 |
Acute undifferentiated leukemia: induction of partial differentiation by phorbol ester.
Topics: Acute Disease; Antibodies, Monoclonal; Antigens, Surface; Cell Differentiation; Humans; Leukemia; Phorbols; Tetradecanoylphorbol Acetate | 1985 |
Rapid morphological and substratum adherence response by hairy cell and other human leukemic cells to phorbol ester tumor promoters.
Topics: Antimetabolites; Cell Adhesion; Cell Differentiation; Cell Membrane; Cells, Cultured; Humans; Leukemia; Leukemia, Hairy Cell; Phorbols; Tetradecanoylphorbol Acetate | 1985 |