tetradecanoylphorbol acetate has been researched along with Leukemia, T-Cell in 61 studies
Timeframe | Studies, this research(%) | All Research% |
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pre-1990 | 8 (13.11) | 18.7374 |
1990's | 43 (70.49) | 18.2507 |
2000's | 8 (13.11) | 29.6817 |
2010's | 2 (3.28) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Hayashi, H; Inoue, Y; Itoh, Y; Miyajima, C | 1 |
Parra, E | 1 |
Baumann, B; Bohnenstengel, F; Debatin, KM; Herr, I; Proksch, P; Siegmund, D; Wajant, H; Weber, C; Wirth, T | 1 |
Dreano, M; Frelin, C; Griessinger, E; Imbert, V; Loubat, A; Peyron, JF | 1 |
Danesh-Manesh, AH; Jeddi-Tehrani, M; Lüppert, A; Mellstedt, H; Mikaelsson, E; Osterborg, A; Rabbani, H; Rezvany, MR; Roohi, A; Safaie, R; Sharifian, RA; Shokri, F | 1 |
Grant, S; Hegde, VL; Jia, W; Nagarkatti, M; Nagarkatti, PS; Singh, NP; Sisco, D | 1 |
Garcia, BH; Hargrave, A; Hommema, E; Kilmer, G; Morgan, A; Nahrahari, J; Webb, B; Wiese, R | 1 |
Aboud, M; Azran-Shaish, I; Bakhanashvili, M; Huleihel, M; Tabakin-Fix, Y | 1 |
Horiguchi, H; Ishikawa, Y; Matsushima, K; Mukaida, N; Murakami, S; Okamoto, S; Rice, N; Yasumoto, K | 1 |
Hardwick, JS; Sefton, BM | 1 |
Goorha, RM; Mao, S; Murti, KG; Neale, GA; Parham, DM | 1 |
Clevers, HC; de Lau, WB; Hashimoto, Y; Kamoun, M; Makni, H; Owen, MJ; Sano, N; Smith, R; van Oers, A; Woods, JS; Wotton, D | 1 |
Bierer, BE; Franklin, DP; Harrison-Findik, D; Hutchcroft, JE; Tsai, B; Varticovski, L | 1 |
Cuthbert, JA; Lipsky, PE; Makar, RS | 1 |
Srivastava, A; Srivastava, BI; Srivastava, MD | 1 |
Beimling, P; Cassens, S; Simon, D; Ulrich, U | 1 |
Bushkin, Y; Demaria, S; Gottesman, SR; Schwab, R | 1 |
Agranoff, AB; Betts, JC; Nabel, GJ; Shayman, JA | 1 |
Arai, K; Arai, N; Muramatsu, M; Tsuboi, A; Tsutsumi, A | 1 |
Grisolano, JL; Hanson, RD; Ley, TJ | 1 |
Fu, KC; Horta, MF; Koizumi, H; Kwon, BS; Liu, CC; Youn, BS; Young, JD | 1 |
Chung, E; Haseltine, WA; Lu, Y; Ueberla, K | 1 |
Hattori, T; Hieshima, K; Hirokawa, K; Miura, R; Nomiyama, H; Takatsuki, K | 1 |
Alzona, M; Hedjbeli, S; Le, PT; Maecker, HT | 1 |
Hirai, H; Mitani, K; Nishida, J; Sakai, R; Tanaka, S; Taniguchi, T; Yamagata, T; Yazaki, Y; Yoshida, M | 1 |
Ao, Z; Hegen, M; Morimoto, C; Schlossman, SF; Wu, MX | 1 |
Bertoglio, J; Binetruy, B; Breard, J; Guizani, L; Perrin-Wolff, M | 1 |
Chuvpilo, S; Heinfling, A; Klein-Hessling, S; Schneider, G; Serfling, E | 1 |
Hiraiwa, M; Hiraiwa, N; Kannagi, R | 1 |
Hirai, H; Kanda, Y; Mitani, K; Ueno, H; Yamagata, T; Yazaki, Y | 1 |
Maurer, HR; Schulze-Forster, K | 1 |
Buckingham, L; Coon, JS; Holian, O; Komarov, PG; Mechetner, EB; Roninson, IB; Shtil, AA; Tee, L | 1 |
De Boer, ML; Kees, UR; Mordvinov, VA; Peroni, SE; Sanderson, CJ | 1 |
Maier, JA; Schiaffonati, L; Tiberio, L | 1 |
Hardy, K; Hunt, NH; Madigan, MC; Pack, RA | 1 |
Fraser, JD; Weiss, A | 1 |
Tchou-Wong, KM; Weinstein, IB | 1 |
Fibbe, WE; Houssiau, FA; Renauld, JC; Van Snick, J | 1 |
De La Rosa, J; Geller, AM; Kotb, M; LeGros, HL | 1 |
Chieco-Bianchi, L; Forino, M; Majone, F; Saggioro, D; Turchetto, L | 1 |
Bensussan, A; Bihoreau, C; Corvaïa, N; Degos, L; Enjalbert, A; Heurtier, A; Kordon, C | 1 |
Bordier, C; Cassar, G; Chiron, M; Darbon, JM; Jaffrezou, JP; Laurent, G; Roubinet, F | 1 |
Child, JA; Jones, RA; Master, PS; Scott, CS | 1 |
Chorváth, B; Dubovský, P; Plesková, I; Sedlák, J | 1 |
Ariyasu, T; Kikuchi, M; Kimura, N; Kohno, K; Minowada, J; Sugamura, K; Watanabe, T | 1 |
Auberger, P; Farahifar, D; Fehlmann, M; Limouse, M; Peyron, JF; Tanti, JF | 1 |
Caixia, S; Stewart, S; Stupack, D; Wilkins, JA | 1 |
Alpers, J; Bradley, K; Cuddy, M; Makover, D; Reed, JC; Sukhatme, V; Yum, S | 1 |
Boursier, MC; Chevalier, S; Gascan, H; Papin, S; Praloran, V; Trossaërt, M | 1 |
Freedman, RS; Ioannides, CG; Liskamp, RM; O'Brian, CA; Ward, NE | 1 |
Carrel, S; Gallay, P; Giuffrè, L; Hayoz, D; Isler, P; Rapin, C; Salvi, S | 1 |
Luo, KX; Sefton, BM | 1 |
Hijikata, M; Kagami, Y; Kato, N; Sato, T; Shimotohno, K | 1 |
Maduro, LJ; Michalides, RJ; Nusse, R; Paardekooper, M; Theunissen, HJ | 1 |
Fridland, A; Goorha, RM; Houghton, JA; Houghton, PJ; Mirro, J; Raimondi, SC | 1 |
Altmeyer, A; Bischoff, P; Hauptmann, G; Moog, C; Waltzinger, C | 1 |
Hurley, TR; Luo, K; Sefton, BM | 1 |
Benedict, SH; Kinsky, SC; Loader, JE | 1 |
Koretzky, GA; Newton, ME; Wahi, M; Weiss, A | 1 |
Benichou, G; Galanaud, P; Kanellopoulos, JM; Leca, G; Mitenne, F | 1 |
Fredholm, BB; Kvanta, A; Nordstedt, C | 1 |
61 other study(ies) available for tetradecanoylphorbol acetate and Leukemia, T-Cell
Article | Year |
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Positive Regulation of Interleukin-2 Expression by a Pseudokinase, Tribbles 1, in Activated T Cells.
Topics: Calcium Ionophores; Carcinogens; Histone Deacetylase 1; Humans; Interleukin-2; Intracellular Signaling Peptides and Proteins; Ionomycin; Jurkat Cells; Leukemia, T-Cell; Lymphocyte Activation; NFATC Transcription Factors; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; T-Lymphocytes; Tetradecanoylphorbol Acetate | 2015 |
Activation of MAP kinase family members triggered by TPA or ionomycin occurs via the protein phosphatase 4 pathway in Jurkat leukemia T cells.
Topics: Calcium Ionophores; Enzyme Activation; Enzyme Inhibitors; Humans; Ionomycin; JNK Mitogen-Activated Protein Kinases; Jurkat Cells; Leukemia, T-Cell; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Okadaic Acid; p38 Mitogen-Activated Protein Kinases; Phosphoprotein Phosphatases; Signal Transduction; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 2012 |
Rocaglamide derivatives are potent inhibitors of NF-kappa B activation in T-cells.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Benzofurans; Cell Line; Dose-Response Relationship, Drug; Gene Expression Regulation; Genes, Reporter; Humans; I-kappa B Kinase; I-kappa B Proteins; Leukemia, T-Cell; Mice; Molecular Structure; NF-kappa B; NF-KappaB Inhibitor alpha; Protein Serine-Threonine Kinases; Rats; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2002 |
AS602868, a pharmacological inhibitor of IKK2, reveals the apoptotic potential of TNF-alpha in Jurkat leukemic cells.
Topics: Antineoplastic Agents; Apoptosis; Caspase 3; Caspase 9; Caspases; Humans; I-kappa B Kinase; Jurkat Cells; Leukemia, T-Cell; Membrane Potentials; Mitochondria; Protein Serine-Threonine Kinases; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2003 |
Fibromodulin, an extracellular matrix protein: characterization of its unique gene and protein expression in B-cell chronic lymphocytic leukemia and mantle cell lymphoma.
Topics: Adult; Aged; Aged, 80 and over; Antigens, CD; Antigens, CD19; Antigens, Differentiation, T-Lymphocyte; Biomarkers, Tumor; Blotting, Western; CD5 Antigens; Cell Line, Transformed; Cell Line, Tumor; Coculture Techniques; Collagen; Cytoplasm; DNA Mutational Analysis; DNA, Complementary; Extracellular Matrix; Extracellular Matrix Proteins; Female; Fibroblasts; Fibromodulin; Flow Cytometry; Gene Expression Regulation, Neoplastic; Hematologic Neoplasms; Humans; Immunoblotting; Lectins, C-Type; Leukemia, B-Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, T-Cell; Leukocytes, Mononuclear; Lymphoma, Mantle-Cell; Male; Middle Aged; Mutation; Palatine Tonsil; Proteoglycans; Receptors, Interleukin-2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors | 2005 |
Delta9-tetrahydrocannabinol-induced apoptosis in Jurkat leukemia T cells is regulated by translocation of Bad to mitochondria.
Topics: Apoptosis; bcl-Associated Death Protein; Caspases; DNA Fragmentation; Down-Regulation; Dronabinol; Extracellular Signal-Regulated MAP Kinases; Humans; Jurkat Cells; Leukemia, T-Cell; MAP Kinase Kinase 1; MAP Kinase Signaling System; Mitochondria; Pertussis Toxin; Protein Kinases; Protein Transport; Proto-Oncogene Proteins c-raf; Receptors, Cannabinoid; Ribosomal Protein S6 Kinases; Tetradecanoylphorbol Acetate; Tissue Distribution; Tumor Cells, Cultured | 2006 |
Antibody microarray analysis of inflammatory mediator release by human leukemia T-cells and human non small cell lung cancer cells.
Topics: Antibodies; Carcinoma, Non-Small-Cell Lung; Cell Line; Cross Reactions; Enzyme-Linked Immunosorbent Assay; Humans; Inflammation Mediators; Leukemia, T-Cell; Lung Neoplasms; Phytohemagglutinins; Sensitivity and Specificity; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2007 |
HTLV-1 tax-induced NF-kappaB activation is synergistically enhanced by 12-O-tetradecanoylphorbol-13-acetate: mechanism and implications for Tax oncogenicity.
Topics: Base Sequence; Carcinogens; Cell Line; CREB-Binding Protein; Cytoplasm; Gene Products, tax; Human T-lymphotropic virus 1; Humans; Jurkat Cells; Leukemia, T-Cell; Molecular Sequence Data; Mutation; NF-kappa B; Tetradecanoylphorbol Acetate; Transfection | 2008 |
The interleukin-8 AP-1 and kappa B-like sites are genetic end targets of FK506-sensitive pathway accompanied by calcium mobilization.
Topics: Base Sequence; Binding Sites; Calcium; Cell Line; Chloramphenicol O-Acetyltransferase; Enzyme-Linked Immunosorbent Assay; Gene Expression; Humans; Interleukin-8; Ionomycin; Kinetics; Leukemia, T-Cell; Luciferases; Molecular Sequence Data; NF-kappa B; Polymerase Chain Reaction; Promoter Regions, Genetic; Proto-Oncogene Proteins c-jun; Sequence Deletion; Suppression, Genetic; T-Lymphocytes; Tacrolimus; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1994 |
Activation of the Lck tyrosine protein kinase by hydrogen peroxide requires the phosphorylation of Tyr-394.
Topics: Amino Acid Sequence; Animals; Base Sequence; Blotting, Western; Cell Line; DNA Primers; Enzyme Activation; Humans; Hydrogen Peroxide; Leukemia, T-Cell; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Lymphocytes; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Mapping; Phosphorylation; Phosphotyrosine; Polymerase Chain Reaction; Protein-Tyrosine Kinases; Rats; Recombinant Proteins; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine | 1995 |
Expression of the proto-oncogene rhombotin-2 is identical to the acute phase response protein metallothionein, suggesting multiple functions.
Topics: Acute-Phase Proteins; Adaptor Proteins, Signal Transducing; Adult; Animals; Brain Chemistry; Cell Nucleus; Child, Preschool; Cycloheximide; DNA-Binding Proteins; Erythropoiesis; Gene Expression Regulation; Humans; Kidney; Leukemia, T-Cell; LIM Domain Proteins; Liver; Metalloproteins; Metallothionein; Mice; Mice, Inbred C57BL; Mice, Transgenic; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogenes; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Thymus Gland; Tumor Cells, Cultured; Zinc | 1995 |
Analysis of CD2 and TCR-beta gene expression in Jurkat cell mutants suggests a cis regulation of gene transcription.
Topics: Antigenic Variation; CD2 Antigens; Cell Differentiation; Gene Expression Regulation, Neoplastic; Gene Transfer Techniques; Genetic Complementation Test; Humans; In Situ Hybridization, Fluorescence; Leukemia, T-Cell; Mutation; Phenotype; Receptors, Antigen, T-Cell, alpha-beta; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured | 1995 |
Phorbol ester treatment inhibits phosphatidylinositol 3-kinase activation by, and association with, CD28, a T-lymphocyte surface receptor.
Topics: Androstadienes; CD28 Antigens; Enzyme Activation; Enzyme Inhibitors; Humans; Interleukin-2; Leukemia, T-Cell; Lymphocyte Activation; Phosphatidylinositol 3-Kinases; Phosphotransferases (Alcohol Group Acceptor); Phosphotyrosine; Precipitin Tests; Protein Binding; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Wortmannin | 1995 |
Non-sterol regulation of low density lipoprotein receptor gene expression in T cells.
Topics: Gene Expression Regulation, Neoplastic; Humans; Ionomycin; Leukemia, T-Cell; Mitogens; Receptors, LDL; Sterols; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Soluble interleukin-2 receptor, soluble CD8 and soluble intercellular adhesion molecule-1 levels in hematologic malignancies.
Topics: Antigens, CD; Biomarkers; Biomarkers, Tumor; CD8 Antigens; Cell Adhesion Molecules; Cell Line; Enzyme-Linked Immunosorbent Assay; Humans; Intercellular Adhesion Molecule-1; Leukemia; Leukemia, Hairy Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid, Acute; Leukemia, Prolymphocytic; Leukemia, T-Cell; Mycosis Fungoides; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Receptors, Interleukin-2; Recurrence; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Inhibition of human T cell leukaemia virus type I long terminal repeat expression by DNA methylation: implications for latency.
Topics: Adult; Base Sequence; Chloramphenicol O-Acetyltransferase; DNA-Cytosine Methylases; DNA, Viral; Gene Products, tax; Human T-lymphotropic virus 1; Humans; Leukemia, T-Cell; Luciferases; Methylation; Repetitive Sequences, Nucleic Acid; Restriction Mapping; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1994 |
Soluble beta 2-microglobulin-free class I heavy chains are released from the surface of activated and leukemia cells by a metalloprotease.
Topics: Antigens, CD; Antigens, Differentiation, B-Lymphocyte; beta 2-Microglobulin; CD4 Antigens; Flow Cytometry; Histocompatibility Antigens Class I; HLA-DR Antigens; Humans; Leukemia, B-Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, T-Cell; Macromolecular Substances; Metalloendopeptidases; Phenanthrolines; Receptors, Transferrin; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Zinc | 1994 |
Dissociation of endogenous cellular ceramide from NF-kappa B activation.
Topics: Antineoplastic Agents; Cell Line; Ceramides; Chloramphenicol O-Acetyltransferase; Genetic Vectors; HIV; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Leukemia, T-Cell; Morpholines; NF-kappa B; Tetradecanoylphorbol Acetate; Time Factors; Transfection; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1994 |
Calcineurin activates transcription from the GM-CSF promoter in synergy with either protein kinase C or NF-kappa B/AP-1 in T cells.
Topics: Animals; Base Sequence; Calcimycin; Calcineurin; Calmodulin-Binding Proteins; Cell Line; Coleoptera; Gene Expression; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukemia, T-Cell; Luciferases; Mice; Models, Genetic; Molecular Sequence Data; NF-kappa B; Oligodeoxyribonucleotides; Phosphoprotein Phosphatases; Plasmids; Promoter Regions, Genetic; Protein Kinases; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; T-Lymphocytes; TATA Box; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1994 |
Consensus AP-1 and CRE motifs upstream from the human cytotoxic serine protease B (CSP-B/CGL-1) gene synergize to activate transcription.
Topics: Base Sequence; Cyclic AMP; DNA; Genes, jun; Granzymes; Humans; Leukemia, T-Cell; Molecular Sequence Data; Point Mutation; Promoter Regions, Genetic; Regulatory Sequences, Nucleic Acid; Serine Endopeptidases; Tetradecanoylphorbol Acetate; Transcriptional Activation; Tumor Cells, Cultured | 1993 |
Identification of a killer cell-specific regulatory element of the mouse perforin gene: an Ets-binding site-homologous motif that interacts with Ets-related proteins.
Topics: Animals; Base Sequence; Binding Sites; Cell Line; Chloramphenicol O-Acetyltransferase; DNA-Binding Proteins; Humans; Interleukin-2; Killer Cells, Lymphokine-Activated; Killer Cells, Natural; Leukemia, T-Cell; Lymphocyte Activation; Mast-Cell Sarcoma; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Molecular Weight; Oligodeoxyribonucleotides; Perforin; Pore Forming Cytotoxic Proteins; Proto-Oncogene Protein c-ets-1; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ets; Recombinant Proteins; Regulatory Sequences, Nucleic Acid; T-Lymphocytes, Cytotoxic; Tetradecanoylphorbol Acetate; Thymoma; Thymus Neoplasms; Transcription Factors; Transfection; Tumor Cells, Cultured | 1993 |
The NF-kappa B p65 promoter.
Topics: Base Sequence; Binding Sites; Chloramphenicol O-Acetyltransferase; Consensus Sequence; Enzyme Activation; Humans; Leukemia, T-Cell; Molecular Sequence Data; NF-kappa B; NF-kappa B p50 Subunit; Phytohemagglutinins; Protein Precursors; Tetradecanoylphorbol Acetate; Transcription Factor RelA; Tumor Cells, Cultured | 1993 |
Characterization of cytokine LD78 gene promoters: positive and negative transcriptional factors bind to a negative regulatory element common to LD78, interleukin-3, and granulocyte-macrophage colony-stimulating factor gene promoters.
Topics: Animals; Base Sequence; Cell Nucleus; Chemokine CCL3; Chemokine CCL4; Chloramphenicol O-Acetyltransferase; Cytokines; DNA Probes; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-3; Leukemia, Erythroblastic, Acute; Leukemia, T-Cell; Luciferases; Macrophage Inflammatory Proteins; Methylation; Mice; Molecular Sequence Data; Monokines; Mutagenesis, Site-Directed; Neoplasm Proteins; Oligodeoxyribonucleotides; Promoter Regions, Genetic; Regulatory Sequences, Nucleic Acid; Restriction Mapping; Sequence Deletion; Sequence Homology, Nucleic Acid; Tetradecanoylphorbol Acetate; Transcription Factors; Transfection; Tumor Cells, Cultured | 1993 |
Comparison of apoptosis signaling through T cell receptor, fas, and calcium ionophore.
Topics: Antibodies, Monoclonal; Apoptosis; Calcimycin; Calcium; CD3 Complex; Cytokines; fas Receptor; Humans; Ionophores; Leukemia, T-Cell; Protein Kinase C; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-myc; Receptors, Antigen, T-Cell; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 1996 |
A novel interferon regulatory factor family transcription factor, ICSAT/Pip/LSIRF, that negatively regulates the activity of interferon-regulated genes.
Topics: Amino Acid Sequence; Animals; Base Sequence; Calcimycin; Carrier Proteins; Consensus Sequence; DNA-Binding Proteins; DNA, Complementary; Gene Expression Regulation; Genes, pX; Humans; Interferon Regulatory Factors; Interferons; Leukemia, T-Cell; Lymphocyte Activation; Molecular Sequence Data; Repressor Proteins; Sequence Homology, Amino Acid; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription Factors; Transcriptional Activation; Tumor Cells, Cultured | 1996 |
Requirement of Fas(CD95), CD45, and CD11a/CD18 in monocyte-dependent apoptosis of human T cells.
Topics: Antigens, CD; Apoptosis; Base Sequence; CD18 Antigens; Cell Death; Fas Ligand Protein; fas Receptor; Humans; Leukemia, T-Cell; Leukocyte Common Antigens; Ligands; Lymphocyte Function-Associated Antigen-1; Membrane Glycoproteins; Molecular Sequence Data; Monocytes; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1996 |
Mechanisms in interleukin-2 protection against glucocorticoid-induced apoptosis: regulation of AP-1 and glucocorticoid receptor transcriptional activities.
Topics: Animals; Antigens, CD; Apoptosis; CHO Cells; Cricetinae; Cricetulus; Dexamethasone; Gene Expression Regulation, Leukemic; Genes, Reporter; Interleukin-2; Leukemia Virus, Gibbon Ape; Leukemia, T-Cell; Receptors, Glucocorticoid; Receptors, Interleukin; Receptors, Interleukin-2; Receptors, Interleukin-4; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcriptional Activation; Tumor Cells, Cultured | 1996 |
HMG I(Y) interferes with the DNA binding of NF-AT factors and the induction of the interleukin 4 promoter in T cells.
Topics: Animals; Base Sequence; Binding, Competitive; Cell Line; Cloning, Molecular; DNA-Binding Proteins; Glutathione Transferase; HeLa Cells; High Mobility Group Proteins; HMGA1a Protein; Humans; Interleukin-4; Leukemia, T-Cell; Lymphocyte Activation; Lymphoma, T-Cell; Mice; Mutagenesis, Site-Directed; NF-kappa B; NFATC Transcription Factors; Nuclear Proteins; Oligodeoxyribonucleotides; Promoter Regions, Genetic; Protein Binding; Recombinant Fusion Proteins; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription Factors | 1996 |
Human T-cell leukemia virus-1 encoded Tax protein transactivates alpha 1-->3 fucosyltransferase Fuc-T VII, which synthesizes sialyl Lewis X, a selectin ligand expressed on adult T-cell leukemia cells.
Topics: Cadmium Chloride; Fucosyltransferases; Gene Products, tax; Human T-lymphotropic virus 1; Humans; Jurkat Cells; Leukemia, T-Cell; Ligands; Oligosaccharides; Selectins; Sialyl Lewis X Antigen; Tetradecanoylphorbol Acetate; Transcriptional Activation; Tumor Cells, Cultured | 1997 |
Triple synergism of human T-lymphotropic virus type 1-encoded tax, GATA-binding protein, and AP-1 is required for constitutive expression of the interleukin-5 gene in adult T-cell leukemia cells.
Topics: Calcimycin; Cyclosporine; DNA-Binding Proteins; GATA4 Transcription Factor; Gene Expression Regulation, Viral; Gene Products, tax; Human T-lymphotropic virus 1; Humans; Immunosuppressive Agents; Interleukin-5; Ionophores; Leukemia, T-Cell; Mutation; Promoter Regions, Genetic; Proto-Oncogene Proteins c-jun; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription Factors; Transcriptional Activation; Transfection; Tumor Cells, Cultured | 1997 |
Expression and modulation of the Lewis x antigen (CD15) on the T cell line Molt-4.
Topics: Adjuvants, Immunologic; Antigens, Surface; Cell Count; Cytokines; Flow Cytometry; Fluorescence; Gene Expression Regulation, Neoplastic; Humans; Leukemia, T-Cell; Lewis X Antigen; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymus Extracts; Tumor Cells, Cultured | 1997 |
Activation of the LRP (lung resistance-related protein) gene by short-term exposure of human leukemia cells to phorbol ester and cytarabine.
Topics: Antimetabolites, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinogens; Cytarabine; Gene Expression Regulation, Leukemic; Genes, MDR; HL-60 Cells; Humans; K562 Cells; Leukemia, Experimental; Leukemia, T-Cell; Neoplasm Proteins; Protein Kinase C; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcriptional Activation; Tumor Cells, Cultured; Vault Ribonucleoprotein Particles | 1998 |
A human T-cell line with inducible production of interleukins 5 and 4. A model for studies of gene expression.
Topics: Base Sequence; Cyclosporine; Dexamethasone; DNA Primers; Gene Expression; Humans; Interleukin-4; Interleukin-5; Jurkat Cells; Leukemia, T-Cell; Models, Biological; RNA, Messenger; RNA, Neoplasm; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcriptional Activation; Tumor Cells, Cultured | 1999 |
Down-modulation of c-myc expression by phorbol ester protects CEM T leukaemia cells from starvation-induced apoptosis: role of ornithine decarboxylase and polyamines.
Topics: Apoptosis; Cell Cycle; Culture Media; Down-Regulation; Gene Expression Regulation, Neoplastic; Humans; Kinetics; Leukemia, T-Cell; Ornithine Decarboxylase; Polyamines; Protein Kinases; Proto-Oncogene Proteins c-myc; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 2001 |
Differential effects of the antioxidant alpha-lipoic acid on the proliferation of mitogen-stimulated peripheral blood lymphocytes and leukaemic T cells.
Topics: Antioxidants; Cell Survival; Dose-Response Relationship, Drug; Humans; Ionomycin; Ionophores; Jurkat Cells; Leukemia, T-Cell; Lymphocyte Activation; Mitogens; Oxidation-Reduction; Phytohemagglutinins; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thioctic Acid | 2002 |
Regulation of T-cell lymphokine gene transcription by the accessory molecule CD28.
Topics: Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Base Sequence; CD28 Antigens; DNA; Gene Expression Regulation; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interferon-gamma; Interleukin-2; Interleukin-3; Ionomycin; Leukemia, T-Cell; Lymphokines; Molecular Sequence Data; Promoter Regions, Genetic; Sequence Homology; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 1992 |
Altered expression of protein kinase C, lck, and CD45 in a 12-O-tetradecanoylphorbol-13-acetate-dependent leukemic T-cell variant that expresses a high level of interleukin-2 receptor.
Topics: Antigens, CD; Blotting, Northern; Cell Division; Gene Expression Regulation; Histocompatibility Antigens; Humans; Kinetics; Leukemia, T-Cell; Leukocyte Common Antigens; Lymphocyte Activation; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Protein Kinase C; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Receptors, Interleukin-2; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
IL-2 dependence of IL-9 expression in human T lymphocytes.
Topics: Antigens, Differentiation, T-Lymphocyte; CD3 Complex; Cells, Cultured; Humans; Interleukin-2; Interleukin-9; Leukemia, T-Cell; Lymphocyte Activation; Receptors, Antigen, T-Cell; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1992 |
Induction of interleukin 2 production but not methionine adenosyltransferase activity or S-adenosylmethionine turnover in Jurkat T-cells.
Topics: Enzyme Precursors; Humans; Interleukin-2; Ionomycin; Leukemia, T-Cell; Lymphocyte Activation; Methionine Adenosyltransferase; Phytohemagglutinins; S-Adenosylmethionine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
Studies on the mechanisms of HTLV-I leukemogenesis.
Topics: Cell Transformation, Neoplastic; DNA Damage; Genes, pX; HTLV-I Infections; Humans; Leukemia, T-Cell; Methylation; Micronucleus Tests; Plasmids; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1992 |
Activation of the CD3/T cell receptor (TcR) complex or of protein kinase C potentiate adenylyl cyclase stimulation in a tumoral T cell line: involvement of two distinct intracellular pathways.
Topics: Adenylyl Cyclases; Antigens, Differentiation, T-Lymphocyte; Arachidonic Acid; Calcium; CD3 Complex; Colforsin; Cyclic AMP; Dinoprostone; Enzyme Activation; Humans; In Vitro Techniques; Inositol Phosphates; Leukemia, T-Cell; Muromonab-CD3; Protein Kinase C; Receptors, Antigen, T-Cell; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
Quantitative analysis of CD5 antigen modulation by 12-O-tetradecanoylphorbol-13-acetate in T-lymphoblastic leukemia cells: individual response patterns and their relationships with both maturation and protein kinase C content.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Antigens, Differentiation; Antigens, Differentiation, T-Lymphocyte; CD5 Antigens; Cell Cycle; Cell Differentiation; Cell Division; Diglycerides; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Isoquinolines; Leukemia, T-Cell; Phenotype; Piperazines; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
The MHC class I associated beta 2-microglobulin (beta 2m) light chain is expressed in a molar excess over HLA-ABC and CD1 on the membrane of leukaemic B cells but not leukaemic T cells: evidence for further beta 2m-associated molecules.
Topics: Antigens, CD; Antigens, CD1; Antigens, Surface; beta 2-Microglobulin; Histocompatibility Antigens Class I; HLA Antigens; Humans; Leukemia, B-Cell; Leukemia, T-Cell; Lymphocyte Activation; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
Differential modulation of leucocyte surface antigens by various inducers on the T-cell line MOLT-4.
Topics: Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Antigens, Neoplasm; Antigens, Surface; CD8 Antigens; Cell Line; Down-Regulation; Drug Synergism; Histocompatibility Antigens; HLA Antigens; Humans; Interferon alpha-2; Interferon-alpha; Leukemia, T-Cell; Leukocyte Common Antigens; Recombinant Proteins; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Up-Regulation | 1991 |
Induced natural killer-like cytotoxic function in the TCR delta-1 positive human leukemic T-cell lines.
Topics: CD4 Antigens; Humans; Killer Cells, Natural; Leukemia, T-Cell; Lymphocyte Function-Associated Antigen-1; Receptors, Antigen, T-Cell, alpha-beta; Receptors, Antigen, T-Cell, gamma-delta; Receptors, Interleukin-2; T-Lymphocytes, Cytotoxic; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
Isolation and characterization of a T lymphocyte mutant defective in the protein kinase C signal transduction pathway.
Topics: Antigens, CD; Biological Transport; Cell Aggregation; Chromatography, Ion Exchange; Cytosol; Dose-Response Relationship, Drug; Humans; Interleukin-2; Leukemia, T-Cell; Lymphocyte Activation; Mutagenesis; Phosphorylation; Protein Kinase C; Ribosomal Protein S6; Ribosomal Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
Beta 1 integrin-mediated lymphocyte adherence to extracellular matrix is enhanced by phorbol ester treatment.
Topics: Cell Adhesion; Collagen; Extracellular Matrix; Fibronectins; Humans; Integrins; Leukemia, T-Cell; Protein Biosynthesis; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
Phorbol ester-mediated inhibition of growth and regulation of proto-oncogene expression in the human T cell leukemia line JURKAT.
Topics: Blotting, Northern; Gene Expression Regulation, Neoplastic; Humans; Leukemia, T-Cell; Nucleic Acid Hybridization; Plasmids; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogenes; Receptors, Interleukin-2; RNA, Messenger; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1991 |
Inducible production of macrophage colony-stimulating factor (CSF-1) by malignant and normal human T cells.
Topics: Antigens, Differentiation, T-Lymphocyte; Blotting, Northern; Calcimycin; Cells, Cultured; Colony-Forming Units Assay; Colony-Stimulating Factors; Humans; Interleukin-1; Leukemia, T-Cell; Macrophage Colony-Stimulating Factor; Monocytes; Phenotype; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1990 |
Inhibition of IL-2 receptor induction and IL-2 production in the human leukemic cell line Jurkat by a novel peptide inhibitor of protein kinase C.
Topics: Amino Acid Sequence; Antibodies, Monoclonal; Cell Division; Gene Expression Regulation; Humans; Interleukin-2; Leukemia, T-Cell; Lymphocyte Activation; Molecular Sequence Data; Muromonab-CD3; Oligopeptides; Phytohemagglutinins; Protein Kinase C; Receptors, Interleukin-2; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
gp33-38, an early human T cell activation antigen.
Topics: Antibodies, Monoclonal; Antigens, Differentiation, T-Lymphocyte; CD3 Complex; Cell Line; Hematopoietic Stem Cells; Humans; Interferon-gamma; Isoelectric Point; Leukemia, T-Cell; Lymphocyte Activation; Membrane Glycoproteins; Molecular Weight; Phytohemagglutinins; Precipitin Tests; Receptors, Antigen, T-Cell; T-Lymphocytes; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured | 1990 |
Analysis of the sites in p56lck whose phosphorylation is induced by tetradecanoyl phorbol acetate.
Topics: Cell Line; Chymotrypsin; Cyanogen Bromide; Humans; Immunohistochemistry; Leukemia, T-Cell; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Peptide Mapping; Phosphopeptides; Phosphorylation; Protein-Tyrosine Kinases; Serine Endopeptidases; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1990 |
Molecular cloning and characterization of a cDNA for a novel phorbol-12-myristate-13-acetate-responsive gene that is highly expressed in an adult T-cell leukemia cell line.
Topics: Amino Acid Sequence; Base Sequence; Cell Line; Cloning, Molecular; Gene Expression Regulation, Neoplastic; Gene Library; Human T-lymphotropic virus 1; Humans; Leukemia, T-Cell; Molecular Sequence Data; Protein Biosynthesis; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1990 |
Phorbol ester-inducible T-cell-specific expression of variant mouse mammary tumor virus long terminal repeats.
Topics: Animals; Cell Line; DNA, Viral; Gene Expression Regulation; Gene Rearrangement; Humans; Leukemia, T-Cell; Mammary Tumor Virus, Mouse; Mice; Proviruses; Repetitive Sequences, Nucleic Acid; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1989 |
Growth and differentiation of a human T-cell leukemia cell line, CCRF-CEM, grafted in mice.
Topics: Animals; Autoradiography; Blotting, Southern; Cell Cycle; Cell Differentiation; Female; Gene Rearrangement, alpha-Chain T-Cell Antigen Receptor; Humans; Immunosuppression Therapy; Karyotyping; Leukemia, T-Cell; Mice; Mice, Inbred CBA; Neoplasm Transplantation; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 1989 |
In vitro modulation of leucocyte-function-associated antigen-1 expression on two leukemic cell lines.
Topics: Antigens, Differentiation; Cell Line; Cytotoxicity, Immunologic; Humans; Immunity, Cellular; Kinetics; Leukemia, Erythroblastic, Acute; Leukemia, T-Cell; Lymphocyte Activation; Lymphocyte Function-Associated Antigen-1; T-Lymphocytes, Cytotoxic; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
Activators of protein kinase C induce dissociation of CD4, but not CD8, from p56lck.
Topics: Animals; Antigens, Differentiation, T-Lymphocyte; Cell Line; Enzyme Activation; Humans; Leukemia, T-Cell; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Phosphorylation; Precipitin Tests; Protein Kinase C; Protein-Tyrosine Kinases; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
Phorbol ester activation of phospholipase D in human monocytes but not peripheral blood lymphocytes.
Topics: B-Lymphocytes; Cell Separation; Enzyme Activation; Ethanol; Glycerophospholipids; Humans; Leukemia, T-Cell; Lymphocytes; Monocytes; Phosphatidic Acids; Phospholipase D; Phospholipases; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
Heterogeneity of protein kinase C isoenzyme gene expression in human T cell lines. Protein kinase C-beta is not required for several T cell functions.
Topics: Cell Line; Gene Expression Regulation; Genes; Humans; Isoenzymes; Leukemia, T-Cell; Phenotype; Protein Kinase C; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1989 |
T-cell chemiluminescence. A novel aspect of T-cell membrane activation studied with a Jurkat tumour cell line.
Topics: Free Radicals; Humans; Lectins; Leukemia, T-Cell; Luminescent Measurements; Lymphocyte Activation; Oxygen; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
Agonist but not phorbol ester induced desensitization of human lymphocyte prostaglandin receptor is dependent on tubulin polymerization.
Topics: Benzimidazoles; Binding, Competitive; Carcinogens; Colchicine; Cyclic AMP; Dinoprostone; Humans; Leukemia, T-Cell; Nocodazole; Phorbol 12,13-Dibutyrate; Phorbol Esters; Receptors, Prostaglandin; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tubulin; Tumor Cells, Cultured | 1988 |