Page last updated: 2024-08-23

tetradecanoylphorbol acetate and Leukemia, Myeloid

tetradecanoylphorbol acetate has been researched along with Leukemia, Myeloid in 284 studies

Research

Studies (284)

TimeframeStudies, this research(%)All Research%
pre-1990103 (36.27)18.7374
1990's135 (47.54)18.2507
2000's38 (13.38)29.6817
2010's7 (2.46)24.3611
2020's1 (0.35)2.80

Authors

AuthorsStudies
Cheong, JW; Chung, H; Hyun, SY; Jang, JE; Kim, JS; Kim, SJ; Kong, JH; Lee, JI; Min, YH; Na, EJ; Shim, KY1
Chen, M; Chen, S; Goodin, S; Huang, H; Li, D; Liu, W; Ma, Y; Patel, N; Ren, X; Zhang, K; Zheng, X; Zhou, R1
Chen, S; Conney, AH; Du, Z; Farichon, C; Goodin, S; He, Y; Huang, H; Li, D; Van Doren, J; Zhang, K; Zhang, Q; Zheng, X1
Chen, YL; Kan, WM1
Baigorri, E; Belch, AR; Chu, MP; Deans, JP; Deng, L; Luider, JM; Mansoor, A; Pilarski, LM; Polyak, MJ; Puri, M; Roberts, L; Sanyal, R; Storek, J; Sundberg, EM; Zuba, A; Zuccolo, J1
Canpinar, H; Esendagli, G; Guc, D; Kansu, E; Kaymaz, FF; Yilmaz, G1
Cui, XY; Dong, CY; Duan, YJ; Gao, WF; Lin, YM; Ma, XT; Yang, BX; Zhang, F1
Ambruso, DR; Ellison, MA; Thurman, GW1
Liu, L; Wang, J; Xiang, G; Xie, L; Zhou, Y1
Han, SS; Keum, YS; Seo, HJ; Surh, YJ1
Chin, KV; Conney, A; Huberman, E; Lin, Y; Rabson, A; Ravatn, R; Shih, WC; Strair, R; Zheng, X1
Aoki, Y; Cioca, DP; Kiyosawa, K1
Nieuwint, AW; Ossenkoppele, GJ; Regelink, JC; Scheper, RJ; Schuurhuis, GJ; Stam, AG; van de Loosdrecht, AA; Westers, TM1
Aggarwal, BB; Majumdar, S1
Haskovec, C; Hradcová, M; Soucek, J; Stöckbauer, P; Ullmannová, V1
Agati, G; Bernabei, PA; Fusi, F; Monici, M; Paglierani, M; Pratesi, R; Santini, V1
Andreu, E; Calasanz, MJ; Fernandez-Luna, JL; Prosper, F; Richard, C; Sanz, C1
Chang, RL; Conney, AH; Hansson, A; Huberman, E; Klemons, S; Lin, Y; Patel, N; Ryan, A; Shih, WJ; Zheng, X1
Chan, RJ; Cripe, LD1
Cohen, S; Dovrat, S; Huberman, E; Salzberg, S; Sarid, R1
Ciardella, M; Goodell, L; Krier, C; Liu, H; Martin, J; Notterman, DA; Osman, M; Schaar, DG; Sharma, S; Strair, RK; Ting, Y1
Chang, RL; Chen, S; Conney, AH; Hansson, A; Huberman, E; Marín, YE; Rabson, AB; Suh, J; Zheng, X1
Harnacke, K; Hass, R; Kruhøffer, M; Orntoft, TF1
Gerlo, S; Kooijman, R; Verdood, P1
Huang, S; Li, AP; Liu, QZ; Mao, WG; Shen, Q; Ye, J; Zhou, JW; Zou, CP1
Berger, F; Champelovier, P; Dupré, I; Elatifi, M; Michoud, A; Pautre, V; Rostaing, B; Seigneurin, D1
Cleaveland, ES; Craig, RW; Eastman, A; Vrana, JA1
Burek, CL; Sharma, RB; Traore, K; Trush, MA1
Harnacke, K; Hass, R; Selle, A; Ullrich, O1
Bohgaki, M; Hatanaka, M; Maeda, S; Matsumoto, E1
Chou, CC; Hsu, CY; Yung, BY1
Huang, HC; Juan, HF1
Kinae, N; Masuda, S; Naitou, H; Ohashi, N; Oya-Ito, T1
Goulet, B; Leduy, L; Markovic, Y; Nepveu, A1
Ball, ED; Fanger, MW; Graziano, RF1
Hozumi, M1
Kakinuma, K; Kitagawa, S; Miura, Y; Nojiri, H; Ohta, M; Saito, M; Takaku, F1
Anderson, NL; Gemmell, MA1
Klein, G; Lau, RY; Nonoyama, M1
Cross, AR; Jones, OT; Roberts, PJ; Segal, AW1
Fürstenberger, G; Marks, F; Sachs, L; Simantov, R1
Ferrero, D; Francis, MK; Matera, L; Santoli, D1
Kuhn, LJ; Niedel, JE; Vandenbark, GR1
Edgington, TS; Mavier, P1
Nagasawa, K1
Chudomel, V; Malasková, V; Soucek, J; Stöckbauer, P1
Bougnoux, P; Chang, ZL; Hattori, T; Hoffman, T; Pack, M1
Dokhelar, MC; Fradelizi, D; Harel, A; Tursz, T; Wakasugi, H1
Fibach, E; Kidron, M; Klemes, Y; Mayer, M1
Bast, RC; Obrist, R; Tarlin, N; Valone, FH1
Chorváth, B; Duraj, J; Stöckbauer, P1
Breton-Gorius, J; Edwards, PA; Garbaz, M; Henri, A; Houesche, F; Pelicci, PG; Rochant, H; Tabilio, A; Testa, U; Thomopoulos, P; Titeux, M; Vainchenker, W; Villeval, JL1
Kitagawa, S; Miura, Y; Ohta, M; Saito, M; Sakamoto, S; Suda, K; Takaku, F1
Fibach, E; Kornberg, A; Rachmilewitz, EA; Treves, A2
Kornatowski, G; Kumar, SA; O'Connor, D; Walsh, J; Yourno, J1
Catovsky, D; Freake, HC; Goldman, JM; McCarthy, DM; Rodriques, B; San Miguel, JF; Zola, H1
Bonner, WM; Pantazis, P1
Beveridge, RP; Griffin, JD; Schlossman, SF1
Litcofsky, PB; Moore, MA; Ralph, P; Williams, N1
Meo, P; Olashaw, N; Rovera, G1
Abrahm, J; Cooper, RA; Lange, B; Levis, A; Meo, P; Pegoraro, L; Rovera, G1
Fibach, E; Rachmilewitz, EA1
Ip, SH; Lebman, D; Perussia, B; Rovera, G; Trinchieri, G1
Honma, Y; Hozumi, M; Kasukabe, T6
Lazarou, SA; Pantazis, P; Papadopoulos, NM1
Takenaga, K1
Goto, Y; Kobayashi, Y; Konno, T; Nakae, S; Okumura, H; Tada, K; Tsuchiya, S1
Koeffler, HP1
Arlin, Z; Clarkson, BD; Holland, JF; Koziner, B; Mendelsohn, N; Svet-Moldavskaya, IA; Svet-Moldavsky, GJ; Zinzar, SN1
Hoffman-Liebermann, B; Liebermann, D; Sachs, L2
Ashman, RF; Billing, R; Chan, G; Golde, DW; Lusis, AJ; Weisbart, RH1
Lotem, J; Sachs, L2
Bonnard, GD; Fruehauf, JP; Herberman, RB1
Brossa, C; D'Alberto, M; Ghezzo, F; Palumbo, A; Pegoraro, L; Turco, GL1
Sachs, L1
Sachs, L; Symonds, G1
Sawabe, T; Seimiya, H; Toho, M; Tsuruo, T1
Hass, R; Meinhardt, G1
Chorváth, B; Duraj, J; Grófová, M; Hunáková, L; Sedlák, J1
Hurme, M; Matikainen, S1
Breton-Gorius, J; Freund, M; Guichard, J; Katz, A; Mouthon, MA; Titeux, M; Vainchenker, W1
Barckow, P; Fiebeler, A; Graham, DK; Huhn, D; Neubauer, A; O'Bryan, JP; Schmidt, CA; Serke, S; Siegert, W; Snodgrass, HR1
Breitman, TR; Takahashi, N1
Bohnsack, JF; Chang, J; Yednock, TA; Zhou, X1
Homann, D; Jakob, F; Köhrle, J; Schneider, D; Seufert, J1
Komada, Y; Sakai, H; Sakatoku, H; Sakurai, M; Tanaka, S; Xue, HL; Zhang, XL; Zhou, YW1
Asiedu, C; Biggs, J; Kraft, AS; Lilly, M1
Buchan, HL; Craig, RW; Kozopas, KM; Yang, T; Zhou, P1
Hurme, M; Keski-Oja, J; Matikainen, S; Taipale, J1
Crane, MK; Gluck, SL; Lee, BS; Underhill, DM1
Edashige, K; Inoue, M; Sato, EF; Utsumi, K1
Bartels, H; Hadam, M; Hass, R; Meinhardt, G1
Darley, RL; Hoy, TG; Jacobs, A; Kuliczkowski, K; Padua, RA1
Donady, JJ; Lievens, PM; Neufeld, EJ; Tufarelli, C1
Devinsky, F; Dierich, MP; Ferencik, M; Kacani, L; Möst, J1
Chen, L; Christman, JK; Xu, M1
Goldberger, A; Middleton, KA; Newman, PJ1
Chow, JM; Kubin, M; Trinchieri, G1
Kojima, N; Saito, M; Tsuji, S1
Chorváth, B; Duraj, J; Holománová, D; Hunáková, L; Sedlák, J1
Chada, S; Newburger, PE; Shen, Q; Whitney, C1
Hayakawa, Y; Ishikawa, T; Niiya, K; Sakuragawa, N; Shinbo, M; Taniguchi, T; Tazawa, S1
Emoto, Y; Kharbanda, S; Kisaki, H; Kufe, D; Saleem, A1
Morimoto, K; Takeuchi, T1
Bhalla, K; Bullock, G; Grant, S; Huang, Y; Ibrado, AM; Mahoney, ME; Ponnathpur, V; Tang, C; Tourkina, E1
Drexler, HG; Hu, ZB; Ma, W; Uphoff, CC1
Crespo, P; Delgado, MD; Gómez-Casares, MT; León, J; Lerga, A; Quincoces, AF; Richard, C1
Seibenhener, ML; Soh, Y; Wooten, MW1
Colombatti, A; Formisano, S; Pucillo, CE; Rossi, G; Salzano, S; Vitale, M1
Emoto, Y; Kharbanda, S; Kufe, D; Rapp, U; Saleem, A; Stone, R1
Ishibashi, T; Nakamura, M; Nishihira, J; Sakamoto, W; Takeichi, N1
Akiyama, N; Hirai, H; Katoh, O; Sasaki, H; Sato, T; Sugimura, T; Terada, M; Yazaki, Y1
Døskeland, SO; Gjertsen, BT; Lanotte, M; Vintermyr, OK1
Maresh, GA; Monnat, RJ1
Beauparlant, P; Hiscott, J; Rice, N; Roulston, A1
Aller, P; Mata, F; Rius, C; Vilaboa, N1
Asseffa, A; Bremner, TA; Dickson, LA; Mohla, S1
Hass, R; Hirano, M; Kharbanda, S; Kufe, D; Meinhardt, G; Rubin, E1
Kruithof, EK; Medcalf, RL; Schuster, WA1
Gaddy-Kurten, D; Hashimoto, M; Vale, W1
Alvarez-Fernández, L; Dosil, M; Gómez-Márquez, J1
Franklin, CC; Hughes, K; Kraft, AS; Leevers, SJ; Pulverer, BJ; Woodgett, JR1
Harris, PE; Hong, B; Lupu, F; Reed, EF; Suciu-Foca, N1
DeWitt, D; Goppelt-Struebe, M; Hoff, T; Kaever, V; Resch, K1
Gunji, H; Hass, R; Hirano, M; Kufe, D; Weichselbaum, R1
Drexler, HG; Steube, KG1
Chen, YC; Lin, DT; Lin, KH; Shen, MC; Tien, HF; Wang, CH1
Antalis, TM; Dickinson, JL1
Buchan, HL; Civin, CI; Craig, RW; Kastan, MB1
Adamski, J; Homann, D; Jakob, F1
Leszczynski, D; Leszczynski, K; Servomaa, K1
Kochetkova, M; Shannon, MF1
Berns, CM; Blackburn, RV; Corry, PM; Galoforo, SS; Huberman, E; Lee, YJ1
Fujino, E; Inoue, N; Kuroiwa, Y; Nakura, H; Numazawa, S; Shinoki, M; Sugiyama, T; Yoshida, T1
Akin, C; Sonnenfeld, G1
Hoffbrand, AV; Mengubas, K; Riordan, FA; Wickremasinghe, RG1
Aizawa, S; Higashihara, M; Horie, R; Inoue, J; Ishida, T; Ito, K; Nagai, M; Takizawa, H; Tatewaki, M; Watanabe, T1
Kurata, S; Matsumoto, M; Nakajima, H1
Fagerholm, S; Leszczynski, D; Leszczynski, K1
Bendall, LJ; Gottlieb, DJ; Kortlepel, K1
Baldi, A; Mladovan, AG; Shayo, CC1
Huberman, E; Hyman, T; Kinar, Y; Lejbkowicz, F; Nir, U; Salzberg, S; Schwartz, Y; Turm, H1
Chow, SC; Orrenius, S; Pörn-Ares, MI; Slotte, JP1
Hass, R; Kruhøffer, M; Prudovsky, I1
Hass, R; Lopez-Guerrero, JA1
Basilico, L; Borleri, GM; Broccoli, V; Erba, E; Faretta, M; Golay, J; Introna, M; Lovrić, J; Mölling, K; Nawrath, M; Piccinini, G; Rambaldi, A; Shapiro, LH; Ying, GG1
Matsuo, O; Niiya, K; Ozawa, T; Sakuragawa, N; Tsuzawa, T; Ueshima, S1
Cao, GS; Chang, RL; Conney, AH; Han, ZT; Liu, XJ; Newmark, HL; Sun, JZ; Tian, GF; Yang, RY; Zhu, XX1
Honma, Y1
Fisher, PB; Grant, S; Su, ZZ; VanTuyle, G; Wang, S; Wang, Z1
Arce, VM; Costoya, JA; Devesa, J; Gallego, R; García-Barros, M; Señarís, R1
Hagiwara, S; Iki, S; Miwa, A; Ozawa, K; Saeki, K; Takaku, F; Togawa, A; Urabe, A; Yuo, A1
Bigas, A; Chernukhin, IV; Delgado, MD; Klenova, EM; León, J1
Gallagher, RE; Huang, XJ; Klein, RS; Wiernik, PH1
Del Vecchio, L; Montuori, N; Ragno, P; Raiola, AM; Risitano, AM; Rossi, G; Rotoli, B; Selleri, C1
Bergan, RC; Blagosklonny, MV; Chuman, Y; Fojo, T1
Gupta, SK; Lysko, PG; Pillarisetti, K1
Alexandrov, I; Kisselev, L; McLennan, A; Prudowski, I; Vartanian, A1
Fabian, I; Fenig, E; Halperin, D; Kalir, HH; Kletter, Y; Nagler, A; Raviv, Z; Witenberg, B1
Klampfer, L; Nimer, SD; Zhang, J1
Aaronson, DS; Ajenjo, N; Ceballos, E; Crespo, P; León, J; Richard, C1
Fisher, AB; Hill, BJ; Hu, X; Moscinski, LC; Valkov, NI; Zuckerman, KS1
Chan, FS; IP, NY; Leung, MF; Xie, P1
Datta, R; Ito, Y; Kharbanda, S; Kufe, D; Nakazawa, A; Pandey, P1
Kim, J; Kim, M; Seo, J1
Hisatake , J; Koeffler, HP; O'Kelly, J; Tomoyasu, S; Uskokovic, MR1
Ito, Y; Kharbanda, S; Kufe, D; Mishra, NC; Saxena, S; Yoshida, K1
Clay, K; Dinauer, M; Hiran, T; Johnson, C; Travers, J1
Breccia, M; Foa, R; Guarini, A; Palmieri, G; Santoni, A; Torelli, GF; Vitale, A1
Johnson, DE; McGuire, TF; Miranda, MB1
Almenara, J; Cartee, L; Dai, Y; Dent, P; Grant, S; Rahmani, M; Rosato, R; Smith, R1
Dai, Y; Grant, S; Rahmani, M1
Damsky, C; Rovera, G; Santoli, D1
Aoki, N; Miwa, M; Nakayasu, M; Sato, S; Shoji, M; Sugimura, T1
Meo, P; Rovera, G; Vorbrodt, A1
Clarkson, BD; Khollend, JF; Svet-Moldavskiĭ, GIa; Svet-Moldavskiĭ, IA1
Arlin, Z; Bekesi, JG; Clarkson, BD; Holland, JF; Koziner, B; Mann, PE; Svet-Moldavskaya, IA; Svet-Moldavsky, GJ; Zinzar, SN1
Hosoya, H; Marunouchi, T1
Kasugai, I; Yamada, M1
Bäuerle, PA; Brach, MA; Herrmann, F; Kufe, DW; Yamada, H1
Nagai, M; Natsumeda, Y; Weber, G1
Buschauer, A; Höer, A; Offermanns, S; Schunack, W; Seifert, R1
Cook, PP; Garris, TO; Messer, BR; Parker, PJ; Qin, W; Ways, DK1
Center, MS; Krishnamachary, N; Ma, L; Perbal, B1
Doenecke, D; Hochhuth, C1
Barendsen, N; Chen, B1
Furukawa, Y; Griffin, JD; Ohta, M; Saito, M; Tsunoda, A; Uenoyama, S1
Datta, R; Gunji, H; Hartmann, A; Hass, R; Kharbanda, S; Kufe, D; Weichselbaum, R1
Center, MS; Krishnamachary, N1
Birnie, GD; Mitchell, LS; Neill, RA1
Okabe-Kado, J1
Kurashige, T; Taniguchi, T; Tomoda, T1
Hurme, M; Matikainen, S; Serkkola, E1
Berk, BC; de Roux, N; Pouysségur, J; Rao, GN; Sardet, C1
Cragoe, EJ; Lotem, J; Sachs, L1
Haskovec, C; Hrouda, V; Plásek, J; Sigler, K1
Oshima, G; Yamada, M1
Collado, A; Garrido, F; Gomez, O; Pedrinaci, S; Ruiz-Cabello, F1
Den, T; Ejima, D; Eto, Y; Scher, W; Svet-Moldavsky, IA1
Budel, LM; Delwel, R; Elbaz, O; Hoogerbrugge, H; Löwenberg, B; Mahmoud, LA; Touw, IP1
Corbett, BR; Corbett, MD; Hannothiaux, MH; Quintana, SJ1
Baker, MA; Bhalla, K; Gervasoni, JE; Knowles, DM; Krishna, S; Lutzky, J; Rosado, M; Ross, DD; Stewart, VJ; Taub, RN1
Back, AL; Gollahon, KA; Hickstein, DD1
Bernstein, SH; Kharbanda, SM; Kufe, DW; Sherman, ML; Stone, RM1
Barreau, P; Basset, M; Cost, H; Geny, B; Le Peuch, C1
Chapman, HA; Nusrat, AR1
Bornens, M; Goud, B; Maridonneau-Parini, I; Yang, CZ1
Chang, KS; Freireich, EJ; Lu, JF; Stass, SA; Trujillo, JM; Wang, YP; Zhao, SR1
Bernstein, S; Datta, R; Hass, R; Kharbanda, S; Kufe, D; Nakamura, T; Stone, R; Sukhatme, VP1
Civin, CI; Craig, RW; Kastan, MB; Kuerbitz, SJ; Onyekwere, O; Radin, AI; Ravindranath, Y; Stone, KD; Wolkow, CA; Woo, T1
Becker, RW; Masemola, AM; Tyobeka, EM1
Goppelt-Struebe, M; Hass, R; Rehfeldt, W1
Chang, KS; Josephs, SF; Liu, WT1
Brach, M; Giese, G; Hass, R; Kharbanda, S; Kufe, D; Traub, P1
Mason, SN; Weinberg, JB1
Datta, R; Kufe, D; Sherman, ML; Stone, RM1
Donelli, A; Ferrari, S; Manfredini, R; Roncaglia, R; Rossi, E; Sarti, M; Tagliafico, E; Torelli, G; Torelli, U1
Barendsen, N; Chen, B; Mueller, M1
Baldwin, GC; Golde, DW; Kitano, K; Raines, MA1
Hurme, M; Ronni, T; Serkkola, E; Silvennoinen, O1
Aquino, A; Borellini, F; Glazer, RI; Josephs, SF1
Bungo, M; Fujiki, H; Fujiwara, Y; Kasahara, K; Nakagawa, K; Niimi, S; Nishio, K; Saijo, N; Sugimoto, Y1
Avigan, MI; Levens, D; Strober, B1
Clemens, MJ; Trayner, ID1
Arcuri, RA; De Souza, MH; Marques-Silva, VM; Rumjanek, VM; Teixeira, MC1
Briggs, JA; Briggs, RC; Gaczynski, M; Lian, JB; Olinski, R; Stein, GS; Uskokovic, M; Wedrychowski, A1
Gross, TJ; Sitrin, RG1
Shiosaka, T; Tanaka, Y1
Horiguchi, J; Kufe, D; Ralph, P; Warren, MK1
Chen, TA; Chou, RH; Wieland, SJ1
Getty, RR; Hauer, CA; Tykocinski, ML1
Barker, S; Brennan, A; Hewison, M; Katz, DR; Nathan, J; O'Riordan, JL1
Duch, DS; Edelstein, MP; Ozaki, Y1
Hoffbrand, AV; Porfiri, E; Wickremasinghe, RG1
Briggs, RC; Duhl, DM; Gaczynski, M; Olinski, R1
Bettens, F; Burke, P; Keller, J; Ruscetti, F; Ruscetti, S; Schlick, E; Sing, G1
Cochran, FR; Finch-Arietta, MB1
Fukumoto, Y; Hamamori, Y; Takai, Y; Tsuda, T; Yamashita, T1
Lopez-Berestein, G; Mehta, K; Murray, JL1
Lopez-Berestein, G; Mehta, K1
Goldman, R1
Collins, SJ; Hickey, MJ; Hickstein, DD1
Krakauer, T1
Drexler, HG; Gaedicke, G; Minowada, J; Otsuka, K1
Beatty, PG; Fisher, W; Harlan, JM; Hickstein, DD; Locksley, RM; Root, RK; Schwartz, BR; Smith, A1
Filli, S; Ioannides, CG; Papamichail, M; Petraki, H1
Kohno, H; Taketani, S; Tokunaga, R1
Brown, D; Fishbaugh, J; Yen, A1
Deli, E; Kiss, Z; Kuo, JF1
Harley, CB; Tyers, M1
Glomset, JA; Goerig, M; Habenicht, AJ; Heitz, R; Katus, H; Kommerell, B; Zeh, W; Ziegler, R1
Ito, Y; Kurata, N; Marunouchi, T; Sawada, M1
Sasaki, M; Yamada, T1
Hayashi, M; Hino, K; Honma, Y; Hozumi, M; Okabe-Kado, J; Sakurai, M; Sampi, K; Tsuruoka, N1
Arai, K; Kondo, A; Matsumoto, M; Taki, T1
Brown, G; Lord, JM; Wong, AK1
Auron, PE; Clark, BD; Fenton, MJ; Vermeulen, MW; Webb, AC1
Ballester, R; Cayre, Y; Makowske, M; Rosen, OM1
Borelli, TJ; Konno, S; Wu, JM1
Barak, V; Biran, S; Halperin, M; Leizerowitz, R; Polliack, A; Treves, AJ1
Colamonici, OR; Neckers, LM; Trepel, JB; Vidal, CA1
Dent, G; Prenant, M; Pryzwansky, KB; Ross, DW1
Hara, A; Ito, K; Shibata, H; Shichijo, S; Shiotsuki, K; Shiraishi, M; Tsunosue, R; Yokoyama, MM1
Alitalo, R1
Nabi, ZF; Zucker-Franklin, D1
Drexler, HG; Gaedicke, G; Minowada, J1
Akiyama, N; Furukawa, Y; Ide, C; Miura, Y; Ohta, M; Saito, M; Utakoji, T1
Bettens, F; Farrar, W; Ruscetti, F; Schlick, E1
Drexler, HG; Gaedicke, G; Hoffbrand, AV; Minowada, J1
Koistinen, P; Vilpo, JA1
Hirai, H; Murakami, T; Takaku, F; Urabe, A1
Andersson, LC; Gahmberg, CG; Stöckbauer, P1
Griffin, J; Kufe, D; Mitchell, T; Sabbath, K; Sariban, E; Watanabe, T1
Drexler, HG; Gaedicke, G; Martin, PJ; Minowada, J; Otsuka, K1
Dokhelar, MC; Fradelizi, D; Garson, D; Harel-Bellan, A; Tursz, T; Wakasugi, H1
Aizu, E; Gotoh, H; Kato, R; Yamamoto, S1

Reviews

7 review(s) available for tetradecanoylphorbol acetate and Leukemia, Myeloid

ArticleYear
Fundamentals of chemotherapy of myeloid leukemia by induction of leukemia cell differentiation.
    Advances in cancer research, 1983, Volume: 38

    Topics: Animals; Arginase; Cell Differentiation; Cell Division; Cell Line; Colony-Stimulating Factors; Dactinomycin; Glucocorticoids; Glycoproteins; Growth Inhibitors; Histones; Humans; Interferons; Interleukin-6; Leukemia Inhibitory Factor; Leukemia, Myeloid; Leukocytes; Lipids; Lymphokines; Lysosomes; Mice; Phenotype; Prostaglandins; Tetradecanoylphorbol Acetate; Vitamin A

1983
[Effect of tumor promotor on neoplastic cell transformation].
    Nihon rinsho. Japanese journal of clinical medicine, 1983, Volume: 41, Issue:2

    Topics: Animals; Carcinogens; Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; Guinea Pigs; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Macrophages; Mice; Phorbols; T-Lymphocytes; Tetradecanoylphorbol Acetate

1983
Control of growth and normal differentiation in leukemic cells: regulation of the developmental program and restoration of the normal phenotype in myeloid leukemia.
    Journal of cellular physiology. Supplement, 1982, Volume: 1

    Topics: Animals; Cell Differentiation; Cell Division; Cell Survival; Colony-Stimulating Factors; Dexamethasone; Gene Expression Regulation; Granulocytes; Hematopoiesis; Humans; Leukemia, Myeloid; Macrophages; Models, Biological; Myeloma Proteins; Tetradecanoylphorbol Acetate

1982
Differentiation and growth modulation of myeloid leukemia cells by the protein kinase C activating agent bryostatin-1.
    Leukemia & lymphoma, 1993, Volume: 9, Issue:1-2

    Topics: Antineoplastic Agents; Bryostatins; Cell Differentiation; Cell Division; Dexamethasone; Drug Interactions; Enzyme Activation; Gene Expression Regulation, Leukemic; Hematopoietic Stem Cells; Humans; Lactones; Leukemia, Myeloid; Macrolides; Neoplastic Stem Cells; Protein Kinase C; Proto-Oncogenes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1993
[Induction of differentiation of leukemia cells].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1998, Volume: 39, Issue:1

    Topics: Cell Differentiation; Cholecalciferol; Drug Synergism; Humans; Leukemia, Myeloid; Oncogenes; Signal Transduction; Tetradecanoylphorbol Acetate

1998
Factors inhibiting differentiation of myeloid leukemia cells.
    Critical reviews in oncogenesis, 1992, Volume: 3, Issue:3

    Topics: Animals; Cell Differentiation; Cytochalasin B; Cytokines; Humans; Leukemia, Myeloid; Prostaglandins; Proto-Oncogenes; Tetradecanoylphorbol Acetate

1992
Human interleukin 1.
    Critical reviews in immunology, 1986, Volume: 6, Issue:3

    Topics: Animals; B-Lymphocytes; Cell Line; Cloning, Molecular; Connective Tissue; Fever; Growth Substances; Humans; Inflammation; Interleukin-1; Interleukin-4; Leukemia, Myeloid; Lymphocyte Activation; Lymphokines; Macrophages; Mice; Monocytes; Monokines; Proteins; Receptors, Immunologic; Receptors, Interleukin-1; T-Lymphocytes; Tetradecanoylphorbol Acetate

1986

Trials

1 trial(s) available for tetradecanoylphorbol acetate and Leukemia, Myeloid

ArticleYear
Effect of intravenous infusions of 12-O-tetradecanoylphorbol-13-acetate (TPA) in patients with myelocytic leukemia: preliminary studies on therapeutic efficacy and toxicity.
    Proceedings of the National Academy of Sciences of the United States of America, 1998, Apr-28, Volume: 95, Issue:9

    Topics: Adult; Aged; Cholecalciferol; Cytarabine; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Tetradecanoylphorbol Acetate

1998

Other Studies

276 other study(ies) available for tetradecanoylphorbol acetate and Leukemia, Myeloid

ArticleYear
Induction of apoptosis and differentiation by Na/H exchanger 1 modulation in acute myeloid leukemia cells.
    Biochemical and biophysical research communications, 2019, 11-19, Volume: 519, Issue:4

    Topics: Acute Disease; Amiloride; Antineoplastic Agents; Apoptosis; Cell Differentiation; Cell Proliferation; G1 Phase Cell Cycle Checkpoints; Humans; K562 Cells; Leukemia, Myeloid; Sodium-Hydrogen Exchanger 1; Tetradecanoylphorbol Acetate

2019
Combination of diethyldithiocarbamate with 12-O-tetradecanoyl phorbol-13-acetate inhibits the growth of human myeloid leukemia HL-60 cells
    Bioscience, biotechnology, and biochemistry, 2020, Volume: 84, Issue:10

    Topics: Animals; Cell Line, Tumor; Cell Proliferation; Ditiocarb; Drug Synergism; Humans; Leukemia, Myeloid; Male; Mice; Proto-Oncogene Proteins c-bcl-2; Tetradecanoylphorbol Acetate; Xenograft Model Antitumor Assays

2020
α-Tomatine inhibits growth and induces apoptosis in HL-60 human myeloid leukemia cells.
    Molecular medicine reports, 2015, Volume: 11, Issue:6

    Topics: Animals; Apoptosis; Body Weight; Cell Proliferation; Cholesterol; Female; HL-60 Cells; Humans; Leukemia, Myeloid; Mice; Mice, SCID; NF-kappa B; Tetradecanoylphorbol Acetate; Tomatine; Transplantation, Heterologous

2015
Down-regulation of superoxide dismutase 1 by PMA is involved in cell fate determination and mediated via protein kinase D2 in myeloid leukemia cells.
    Biochimica et biophysica acta, 2015, Volume: 1853, Issue:10 Pt A

    Topics: Carcinogens; Down-Regulation; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Leukemic; Humans; K562 Cells; Leukemia, Myeloid; Molybdenum; Neoplasm Proteins; Poly(ADP-ribose) Polymerases; Protein Kinase D2; Protein Kinases; Signal Transduction; Superoxide Dismutase; Superoxide Dismutase-1; Tetradecanoylphorbol Acetate

2015
MS4A4A: a novel cell surface marker for M2 macrophages and plasma cells.
    Immunology and cell biology, 2017, Volume: 95, Issue:7

    Topics: B-Lymphocytes; Biomarkers; Blood Cells; Bone Marrow; Cell Differentiation; Cell Lineage; Cell Membrane; Dendritic Cells; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid; Macrophages; Membrane Proteins; Monocytes; Plasma Cells; Tetradecanoylphorbol Acetate; U937 Cells; Up-Regulation

2017
Fibronectin promotes the phorbol 12-myristate 13-acetate-induced macrophage differentiation in myeloid leukemia cells.
    International journal of hematology, 2009, Volume: 89, Issue:2

    Topics: Fibronectins; HL-60 Cells; Humans; Leukemia, Myeloid; Macrophages; Myeloid Cells; Tetradecanoylphorbol Acetate

2009
Novel functions for mda-7/IL-24 and IL-24 delE5: regulation of differentiation of acute myeloid leukemic cells.
    Molecular cancer therapeutics, 2011, Volume: 10, Issue:4

    Topics: Acute Disease; Alternative Splicing; Animals; Blotting, Western; Cell Differentiation; Enzyme Activation; Gene Expression Regulation, Neoplastic; HL-60 Cells; Humans; Interleukins; Leukemia, Myeloid; Mice; Mice, Nude; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neoplasms, Experimental; Protein Isoforms; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Tetradecanoylphorbol Acetate; Transplantation, Heterologous; Tumor Burden; U937 Cells

2011
Phox activity of differentiated PLB-985 cells is enhanced, in an agonist specific manner, by the PLA2 activity of Prdx6-PLA2.
    European journal of immunology, 2012, Volume: 42, Issue:6

    Topics: Cell Line, Tumor; Humans; Leukemia, Myeloid; NADPH Oxidases; Peroxiredoxin VI; Phospholipases A2; Superoxides; Tetradecanoylphorbol Acetate; Tretinoin

2012
Induction of differentiation-specific miRNAs in TPA-induced myeloid leukemia cells through MEK/ERK activation.
    International journal of molecular medicine, 2013, Volume: 31, Issue:1

    Topics: Cell Differentiation; Gene Expression Regulation; HL-60 Cells; Humans; K562 Cells; Leukemia, Myeloid; MAP Kinase Signaling System; Microarray Analysis; MicroRNAs; Mitogen-Activated Protein Kinases; Myeloid Cells; Phosphorylation; RNA Processing, Post-Transcriptional; Tetradecanoylphorbol Acetate; U937 Cells

2013
Curcumin suppresses activation of NF-kappaB and AP-1 induced by phorbol ester in cultured human promyelocytic leukemia cells.
    Journal of biochemistry and molecular biology, 2002, May-31, Volume: 35, Issue:3

    Topics: Anticarcinogenic Agents; Carcinogens; Consensus Sequence; Curcumin; DNA-Binding Proteins; Electrophoretic Mobility Shift Assay; Genes, Regulator; HL-60 Cells; Humans; I-kappa B Proteins; Leukemia, Myeloid; NF-kappa B; NF-KappaB Inhibitor alpha; Promoter Regions, Genetic; Protein Transport; Tetradecanoylphorbol Acetate; Transcription Factor AP-1

2002
Gene expression of TPA induced differentiation in HL-60 cells by DNA microarray analysis.
    Nucleic acids research, 2002, Oct-15, Volume: 30, Issue:20

    Topics: Antineoplastic Agents; Cell Differentiation; Drug Resistance, Neoplasm; Gene Expression Profiling; HL-60 Cells; Humans; Kinetics; Leukemia, Myeloid; Oligonucleotide Array Sequence Analysis; RNA, Neoplasm; Tetradecanoylphorbol Acetate

2002
RNA interference is a functional pathway with therapeutic potential in human myeloid leukemia cell lines.
    Cancer gene therapy, 2003, Volume: 10, Issue:2

    Topics: Antineoplastic Agents, Phytogenic; Cell Death; Cell Differentiation; Daunorubicin; Etoposide; Gene Expression Regulation, Neoplastic; Genetic Therapy; HL-60 Cells; Humans; Leukemia, Myeloid; Oligodeoxyribonucleotides, Antisense; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-raf; RNA Interference; RNA, Double-Stranded; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

2003
Rapid generation of antigen-presenting cells from leukaemic blasts in acute myeloid leukaemia.
    Cancer immunology, immunotherapy : CII, 2003, Volume: 52, Issue:1

    Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Antigen-Presenting Cells; Antigens, CD; Antigens, Neoplasm; Bone Marrow Cells; Calcimycin; Calcium; Cancer Vaccines; Cell Culture Techniques; Cryopreservation; Cytotoxicity, Immunologic; Feasibility Studies; Female; HLA-DR Antigens; Humans; Interleukin-4; Ionophores; Leukemia, Myeloid; Lymphocyte Culture Test, Mixed; Male; Middle Aged; Neoplastic Cells, Circulating; Neoplastic Stem Cells; Reproducibility of Results; T-Lymphocytes, Cytotoxic; Tetradecanoylphorbol Acetate; Time Factors; Tissue Preservation; Tumor Cells, Cultured; Vaccination

2003
Adenosine suppresses activation of nuclear factor-kappaB selectively induced by tumor necrosis factor in different cell types.
    Oncogene, 2003, Feb-27, Volume: 22, Issue:8

    Topics: Adenosine; Alkaline Phosphatase; Antigens, CD; Cells, Cultured; Ceramides; Dose-Response Relationship, Drug; Gene Expression Regulation, Leukemic; Gene Expression Regulation, Neoplastic; Genes, Reporter; HeLa Cells; Humans; Hydrogen Peroxide; I-kappa B Kinase; I-kappa B Proteins; Jurkat Cells; Kidney; Leukemia, Myeloid; Lipopolysaccharides; Monocytes; Neoplasm Proteins; NF-kappa B; NF-KappaB Inhibitor alpha; NF-kappaB-Inducing Kinase; Okadaic Acid; Protein Serine-Threonine Kinases; Proteins; Purinergic P1 Receptor Agonists; Receptors, Purinergic P1; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type I; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Thymidine; TNF Receptor-Associated Factor 2; Transcription, Genetic; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Uridine

2003
Relationship between cyclin D1 and p21(Waf1/Cip1) during differentiation of human myeloid leukemia cell lines.
    Leukemia research, 2003, Volume: 27, Issue:12

    Topics: Acute Disease; Antineoplastic Agents; Blotting, Western; Carcinogens; Cell Cycle; Cell Differentiation; Cell Division; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA Primers; Humans; Interferon-gamma; Leukemia, Myeloid; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Up-Regulation

2003
Dependence of leukemic cell autofluorescence patterns on the degree of differentiation.
    Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 2003, Volume: 2, Issue:10

    Topics: Cell Differentiation; Cell Line, Tumor; Fluorescence; Histocytochemistry; HL-60 Cells; Humans; Immunohistochemistry; In Vitro Techniques; Leukemia, Myeloid; Microscopy, Fluorescence; Photobiology; Tetradecanoylphorbol Acetate; Thymidine; Tretinoin

2003
NALP1 is a transcriptional target for cAMP-response-element-binding protein (CREB) in myeloid leukaemia cells.
    The Biochemical journal, 2004, Dec-01, Volume: 384, Issue:Pt 2

    Topics: Adaptor Proteins, Signal Transducing; Apoptosis Regulatory Proteins; Base Sequence; Binding Sites; Cell Line, Tumor; Cyclic AMP Response Element-Binding Protein; Gene Expression Regulation, Neoplastic; Hematopoietic Stem Cells; Humans; K562 Cells; Leukemia, Erythroblastic, Acute; Leukemia, Myeloid; Molecular Sequence Data; NLR Proteins; Promoter Regions, Genetic; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Transcription, Genetic

2004
Synergistic stimulatory effect of 12-O-tetradecanoylphorbol-13-acetate and capsaicin on macrophage differentiation in HL-60 and HL-525 human myeloid leukemia cells.
    International journal of oncology, 2005, Volume: 26, Issue:2

    Topics: Alkaloids; Antineoplastic Agents; Benzophenanthridines; Capsaicin; Carboxylesterase; Carcinogens; Cell Adhesion; Cell Differentiation; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Enzyme Inhibitors; HL-60 Cells; Humans; Leukemia, Myeloid; Macrophages; Models, Chemical; Phenanthridines; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors

2005
12-O-Tetradecanoylphorbol-13-acetate in acute myeloid leukemia.
    Leukemia research, 2005, Volume: 29, Issue:10

    Topics: Acute Disease; Apoptosis; Carcinogens; Cell Cycle Proteins; Dual Specificity Phosphatase 1; Humans; Immediate-Early Proteins; Leukemia, Myeloid; Phosphoprotein Phosphatases; Phosphorylation; Protein Phosphatase 1; Protein Tyrosine Phosphatases; Signal Transduction; Tetradecanoylphorbol Acetate

2005
JAK-STAT signaling involved in phorbol 12-myristate 13-acetate- and dimethyl sulfoxide-induced 2'-5' oligoadenylate synthetase expression in human HL-60 leukemia cells.
    Leukemia research, 2005, Volume: 29, Issue:8

    Topics: 2',5'-Oligoadenylate Synthetase; Catalysis; Cell Cycle Proteins; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Dimethyl Sulfoxide; DNA-Binding Proteins; Enzyme Activation; Gene Expression Regulation, Enzymologic; Genes, bcl-1; HL-60 Cells; Humans; Janus Kinase 1; Leukemia, Myeloid; Protein-Tyrosine Kinases; Signal Transduction; STAT1 Transcription Factor; Tetradecanoylphorbol Acetate; Trans-Activators

2005
12-O-tetradecanoylphorbol-13-acetate (TPA)-induced dual-specificity phosphatase expression and AML cell survival.
    Leukemia research, 2005, Volume: 29, Issue:10

    Topics: Acute Disease; Apoptosis; Blotting, Western; Carcinogens; Cell Cycle Proteins; Cell Survival; Dual Specificity Phosphatase 1; Gene Expression Profiling; Humans; Immediate-Early Proteins; Leukemia, Myeloid; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Oligonucleotide Array Sequence Analysis; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase Inhibitors; Protein Phosphatase 1; Protein Tyrosine Phosphatases; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Tetradecanoylphorbol Acetate

2005
Enhancement of TPA-induced growth inhibition and apoptosis in myeloid leukemia cells by BAY 11-7082, an NF-kappaB inhibitor.
    International journal of oncology, 2005, Volume: 27, Issue:4

    Topics: Active Transport, Cell Nucleus; Apoptosis; Cell Adhesion; Cell Differentiation; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Cell Survival; DNA; DNA Damage; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; HL-60 Cells; Humans; I-kappa B Proteins; Immunophenotyping; Leukemia, Myeloid; NF-kappa B; NF-KappaB Inhibitor alpha; Nitriles; Phosphorylation; Propidium; Protein Kinase C; Protein Kinase C beta; Sulfones; Tetradecanoylphorbol Acetate; Time Factors

2005
Down-modulation of poly(ADP-ribose) polymerase-1 (PARP-1) in human TUR leukemia cells restores transcriptional responsiveness for differentiation and cell cycle arrest.
    European journal of cell biology, 2005, Volume: 84, Issue:11

    Topics: Cell Adhesion; Cell Culture Techniques; Cell Cycle; Cell Differentiation; Down-Regulation; Flow Cytometry; Humans; Leukemia, Myeloid; Microarray Analysis; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured

2005
Tumor necrosis factor-alpha activates the extrapituitary PRL promoter in myeloid leukemic cells.
    Journal of neuroimmunology, 2006, Volume: 172, Issue:1-2

    Topics: Analysis of Variance; Cell Line; Drug Interactions; Electrophoretic Mobility Shift Assay; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation; Humans; Indoles; Leukemia, Myeloid; Maleimides; Mutagenesis; Prolactin; Promoter Regions, Genetic; Tetradecanoylphorbol Acetate; Transfection; Tumor Necrosis Factor-alpha

2006
JWA, a novel signaling molecule, involved in the induction of differentiation of human myeloid leukemia cells.
    Biochemical and biophysical research communications, 2006, Mar-10, Volume: 341, Issue:2

    Topics: Blotting, Western; Bone Marrow Cells; Cell Cycle; Cell Differentiation; Cell Line, Tumor; Cells, Cultured; Cytarabine; Gene Silencing; Granulocytes; Heat-Shock Proteins; Hemin; HL-60 Cells; Humans; Intracellular Signaling Peptides and Proteins; K562 Cells; Leukemia, Myeloid; Macrophages; Membrane Transport Proteins; Monocytes; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Tetradecanoylphorbol Acetate; Time Factors; Tretinoin; U937 Cells

2006
Resistance to phorbol ester-induced differentiation in human myeloid leukemia cells: a hypothetic role for the mRNA stabilization process.
    Leukemia research, 2006, Volume: 30, Issue:11

    Topics: Cell Cycle Proteins; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Gene Expression Profiling; HL-60 Cells; Humans; Intercellular Adhesion Molecule-1; Leukemia, Myeloid; Naphthalenes; Oligonucleotide Array Sequence Analysis; Protein Kinase C; Protein Kinase C beta; Reverse Transcriptase Polymerase Chain Reaction; RNA Stability; RNA, Messenger; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Necrosis Factor-alpha; U937 Cells

2006
Inducer-and cell type-specific regulation of antiapoptotic MCL1 in myeloid leukemia and multiple myeloma cells exposed to differentiation-inducing or microtubule-disrupting agents.
    Apoptosis : an international journal on programmed cell death, 2006, Volume: 11, Issue:8

    Topics: Apoptosis; Cell Differentiation; Cell Line, Tumor; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation, Neoplastic; Humans; JNK Mitogen-Activated Protein Kinases; Leukemia, Myeloid; Microtubules; Multiple Myeloma; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; p38 Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins c-bcl-2; Tetradecanoylphorbol Acetate; Tubulin Modulators; U937 Cells; Vinblastine

2006
Role of ROS and MAPK in TPA-induced ICAM-1 expression in the myeloid ML-1 cell line.
    Journal of cellular biochemistry, 2007, Mar-01, Volume: 100, Issue:4

    Topics: Blotting, Western; Butadienes; Cell Line, Tumor; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Indoles; Intercellular Adhesion Molecule-1; Leukemia, Myeloid; Maleimides; Mitogen-Activated Protein Kinases; Models, Biological; NF-kappa B; Nitriles; Oligonucleotide Array Sequence Analysis; Protein Kinase C; Reactive Oxygen Species; Signal Transduction; Sulfones; Tetradecanoylphorbol Acetate

2007
Retrodifferentiation and rejuvenation of senescent monocytic cells requires PARP-1.
    Experimental gerontology, 2007, Volume: 42, Issue:6

    Topics: Apoptosis; Benzamides; Cell Differentiation; Cell Proliferation; Cellular Senescence; DNA, Antisense; Humans; Leukemia, Myeloid; Leupeptins; Monocytes; Phenotype; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Proteasome Endopeptidase Complex; Tetradecanoylphorbol Acetate; U937 Cells

2007
PKC pathway and ERK/MAPK pathway are required for induction of cyclin D1 and p21Waf1 during 12-o-tetradecanoylphorbol 13-acetate-induced differentiation of myeloleukemia cells.
    The Kobe journal of medical sciences, 2006, Volume: 52, Issue:6

    Topics: Cell Differentiation; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p21; Cycloheximide; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation, Leukemic; HL-60 Cells; Humans; Leukemia, Myeloid; p38 Mitogen-Activated Protein Kinases; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; U937 Cells

2006
Involvement of nPKC-MAPK pathway in the decrease of nucleophosmin/B23 during megakaryocytic differentiation of human myelogenous leukemia K562 cells.
    Life sciences, 2007, May-08, Volume: 80, Issue:22

    Topics: Carbazoles; Cell Differentiation; Cell Line, Tumor; Humans; Indoles; K562 Cells; Leukemia, Myeloid; Maleimides; Megakaryocytes; Mitogen-Activated Protein Kinases; Nuclear Proteins; Nucleolin; Nucleophosmin; Phosphoproteins; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Kinase C; RNA-Binding Proteins; Tetradecanoylphorbol Acetate

2007
Bioinformatics: microarray data clustering and functional classification.
    Methods in molecular biology (Clifton, N.J.), 2007, Volume: 382

    Topics: Carcinogens; Cluster Analysis; Computational Biology; Gene Expression Profiling; Humans; Leukemia, Myeloid; Oligonucleotide Array Sequence Analysis; Pattern Recognition, Automated; Software; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

2007
Functional analyses of neutrophil-like differentiated cell lines under a hyperglycemic condition.
    Molecular nutrition & food research, 2008, Volume: 52, Issue:3

    Topics: Cell Aggregation; Cell Differentiation; Cell Line, Tumor; Glucose; HL-60 Cells; Humans; Hyperglycemia; Leukemia, Myeloid; Mannitol; Neutrophils; Phagocytosis; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Vacuoles

2008
Proteolytic processing of cut homeobox 1 by neutrophil elastase in the MV4;11 myeloid leukemia cell line.
    Molecular cancer research : MCR, 2008, Volume: 6, Issue:4

    Topics: Cell Extracts; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Cyclin E; Gene Expression Regulation, Neoplastic; Homeodomain Proteins; Humans; Leukemia, Myeloid; Leukocyte Elastase; Protein Processing, Post-Translational; Recombinant Proteins; Serine Proteinase Inhibitors; Tetradecanoylphorbol Acetate

2008
The expression and modulation of human myeloid-specific antigens during differentiation of the HL-60 cell line.
    Blood, 1983, Volume: 61, Issue:6

    Topics: Animals; Antigens, Neoplasm; Antigens, Surface; Cell Differentiation; Cell Line; Dimethyl Sulfoxide; Dimethylformamide; Epitopes; Granulocytes; Humans; Hybridomas; Leukemia, Myeloid; Mice; Tetradecanoylphorbol Acetate; Tretinoin

1983
Functional maturation of membrane potential changes and superoxide-producing capacity during differentiation of human granulocytes.
    The Journal of clinical investigation, 1984, Volume: 73, Issue:4

    Topics: Adult; Calcimycin; Cell Differentiation; Cell Transformation, Neoplastic; Deoxyglucose; Dimethyl Sulfoxide; Gramicidin; Granulocytes; Humans; Leukemia, Myeloid; Membrane Potentials; Phagocytosis; Superoxides; Tetradecanoylphorbol Acetate; Tretinoin

1984
Protein-pattern changes and morphological effects due to methionine starvation or treatment with 5-azacytidine of the phorbol-ester-sensitive cell lines HL-60, CCL-119, and U-937.
    Clinical chemistry, 1984, Volume: 30, Issue:12 Pt 1

    Topics: Azacitidine; Cell Line; Cell Nucleus; Cytoskeleton; Electrophoresis, Polyacrylamide Gel; Humans; Isoelectric Focusing; Leukemia, Myeloid; Lymphoma; Methionine; Protein Biosynthesis; Proteins; T-Lymphocytes; Tetradecanoylphorbol Acetate

1984
Somatic cell hybrids between human lymphoma and human myeloid leukemia cells. I. Induction of resident viral genome transcription and viral antigen formation by IUDR and TPA.
    Virology, 1981, Apr-30, Volume: 110, Issue:2

    Topics: Antigens, Viral; Cells, Cultured; DNA, Viral; Genes, Viral; Herpesvirus 4, Human; Humans; Hybrid Cells; Idoxuridine; Leukemia, Myeloid; RNA, Viral; Tetradecanoylphorbol Acetate; Transcription, Genetic; Virus Replication

1981
Development of cytochrome b and an active oxidase system in association with maturation of a human promyelocytic (HL-60) cell line.
    The Journal of cell biology, 1982, Volume: 95, Issue:3

    Topics: Cell Line; Cell Membrane; Cytochrome b Group; Dimethyl Sulfoxide; Electron Transport Complex IV; Glucose; Granulocytes; Hematopoiesis; Humans; Leukemia, Myeloid; Mitochondria; Oxidoreductases; Oxygen Consumption; Peroxidase; Tetradecanoylphorbol Acetate

1982
Control of endogenous cell regulators by the second-stage tumor promoter phorbol-12-retinoate 13-acetate.
    International journal of cancer, 1983, Apr-15, Volume: 31, Issue:4

    Topics: Animals; Binding, Competitive; Cell Differentiation; Cells, Cultured; Cyclic AMP; Glycoproteins; Growth Inhibitors; Interleukin-6; Leukemia Inhibitory Factor; Leukemia, Myeloid; Lymphokines; Mice; Muramidase; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Prostaglandins E; Tetradecanoylphorbol Acetate

1983
Induction of proliferation and NK activity in human lymphocytes by mature myelomonocytic cells: evidence for an HLA-DR-independent MLR stimulatory ability of terminally differentiated nonlymphoid leukemic cell lines and of normal peripheral blood granuloc
    Journal of immunology (Baltimore, Md. : 1950), 1983, Volume: 131, Issue:2

    Topics: Cell Differentiation; Cell Division; Cell Line; Dimethyl Sulfoxide; Granulocytes; Histiocytoma, Benign Fibrous; Histocompatibility Antigens Class II; HLA-DR Antigens; Humans; Killer Cells, Natural; Leukemia, Myeloid; Lymphoma; Tetradecanoylphorbol Acetate; Tretinoin

1983
Possible mechanism of phorbol diester-induced maturation of human promyelocytic leukemia cells.
    The Journal of clinical investigation, 1984, Volume: 73, Issue:2

    Topics: Caenorhabditis elegans Proteins; Carrier Proteins; Cell Differentiation; Cell Line; Enzyme Activation; Humans; Leukemia, Myeloid; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Kinase C; Protein Kinases; Receptors, Cell Surface; Receptors, Drug; Tetradecanoylphorbol Acetate

1984
Human monocyte-mediated tumor cytotoxicity. I. Demonstration of an oxygen-dependent myeloperoxidase-independent mechanism.
    Journal of immunology (Baltimore, Md. : 1950), 1984, Volume: 132, Issue:4

    Topics: Cell Line; Cytotoxicity, Immunologic; Free Radicals; Humans; Hydrogen Peroxide; Leukemia, Myeloid; Lymphoma, Large B-Cell, Diffuse; Monocytes; Oxygen Consumption; Peroxidase; Tetradecanoylphorbol Acetate

1984
Differentiation of human myeloid leukemia cell lines induced by tumor-promoting phorbol ester (TPA). I. Changes of the morphology, cytochemistry and the surface differentiation antigens analyzed with monoclonal antibodies.
    Neoplasma, 1983, Volume: 30, Issue:3

    Topics: Acid Phosphatase; Antibodies, Monoclonal; Antigens, Neoplasm; Carboxylic Ester Hydrolases; Cell Differentiation; Cell Line; Fluorescent Antibody Technique; Histocompatibility Antigens Class II; Histocytochemistry; HLA Antigens; HLA-A Antigens; HLA-DR Antigens; Humans; Leukemia, Myeloid; Lymphoma, Large B-Cell, Diffuse; Naphthol AS D Esterase; Neoplasms, Experimental; Tetradecanoylphorbol Acetate

1983
Interferon-induced differentiation of U937 cells. Comparison with other agents that promote differentiation of human myeloid or monocytelike cell lines.
    The Journal of clinical investigation, 1983, Volume: 72, Issue:1

    Topics: Antigens; Cell Differentiation; Cell Line; Cytotoxicity, Immunologic; Dimethyl Sulfoxide; Granulocytes; Humans; Interferon Type I; Leukemia, Myeloid; Lymphoma, Large B-Cell, Diffuse; Monocytes; Tetradecanoylphorbol Acetate

1983
Accessory function and interleukin 1 production by human leukemic cell lines.
    Journal of immunology (Baltimore, Md. : 1950), 1984, Volume: 132, Issue:6

    Topics: Cell Line; Cell Transformation, Neoplastic; Histocompatibility Antigens Class II; HLA-DR Antigens; Humans; Interleukin-1; Isoelectric Focusing; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lymphocyte Activation; Lymphocyte Cooperation; Lymphoma, Large B-Cell, Diffuse; Monocytes; Phenotype; Phytohemagglutinins; T-Lymphocytes; Tetradecanoylphorbol Acetate

1984
Inhibition of phorbol-ester-induced adhesion of differentiating human myeloid leukemic cells by pentamidine-isethionate.
    Differentiation; research in biological diversity, 1984, Volume: 27, Issue:2

    Topics: Amidines; Cell Adhesion; Cell Differentiation; Cell Line; Humans; Leukemia, Myeloid; Pentamidine; Peptide Hydrolases; Phorbols; Protease Inhibitors; Tetradecanoylphorbol Acetate

1984
Enhanced arachidonic acid lipoxygenation by K562 cells stimulated with 12-O-tetradecanoylphorbol-13-acetate.
    Cancer research, 1983, Volume: 43, Issue:1

    Topics: Arachidonate Lipoxygenases; Humans; Leukemia, Myeloid; Lipoxygenase; Phorbols; Tetradecanoylphorbol Acetate; Time Factors

1983
Differentiation of human myeloid leukemia cell lines induced by tumor-promoting phorbol ester (TPA). II. Electrophoretic patterns of metabolically- and cell surface radiolabeled proteins and glycoproteins.
    Neoplasma, 1983, Volume: 30, Issue:3

    Topics: Cell Differentiation; Cell Line; Electrophoresis; Glycoproteins; Humans; Isoelectric Focusing; Leukemia, Myeloid; Membrane Proteins; Neoplasm Proteins; Tetradecanoylphorbol Acetate

1983
Erythroid properties of K562 cells. Effect of hemin, butyrate and TPA induction.
    Experimental cell research, 1983, Volume: 146, Issue:2

    Topics: Acetylcholinesterase; Butyrates; Butyric Acid; Cell Line; Erythrocytes; Erythropoiesis; Glycophorins; Hemin; Hemoglobins; Humans; Leukemia, Myeloid; Sialoglycoproteins; Spectrin; Tetradecanoylphorbol Acetate

1983
Differentiation of human leukemia cells and its usefulness for clinical diagnosis.
    Leukemia research, 1983, Volume: 7, Issue:3

    Topics: Cell Differentiation; Clinical Laboratory Techniques; Diagnosis, Differential; Humans; Leukemia; Leukemia, Hairy Cell; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukemia, Plasma Cell; Tetradecanoylphorbol Acetate

1983
Generation of procoagulant activity (PCA) by macrophage-like cells derived from acute and chronic myeloid leukaemia cells in response to phorbol esters.
    Scandinavian journal of haematology, 1983, Volume: 31, Issue:2

    Topics: Adolescent; Adult; Aged; Blood Coagulation; Blood Coagulation Disorders; Blood Coagulation Factors; Cell Differentiation; Cell Separation; Cells, Cultured; Child; Child, Preschool; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Macrophages; Middle Aged; Monocytes; Phorbols; Reference Values; Tetradecanoylphorbol Acetate

1983
Nonspecific esterases of leukemia cell lines: evidence for activation of myeloid-associated zymogens in HL-60 by phorbol esters.
    Blood, 1984, Volume: 63, Issue:1

    Topics: Cell Line; Cell Transformation, Neoplastic; Enzyme Activation; Enzyme Precursors; Esterases; Humans; Isoenzymes; Leukemia, Myeloid; Phorbols; Tetradecanoylphorbol Acetate

1984
Changes in surface antigens of HL-60 cells during differentiation in vitro.
    Blut, 1984, Volume: 49, Issue:5

    Topics: Antibodies, Monoclonal; Antibody Specificity; Antigens, Surface; Calcitriol; Cell Differentiation; Cell Line; In Vitro Techniques; Leukemia, Myeloid; Tetradecanoylphorbol Acetate

1984
Specific alterations in the pattern of histone-3 synthesis during conversion of human leukemic cells to terminally differentiated cells in culture.
    Differentiation; research in biological diversity, 1984, Volume: 28, Issue:2

    Topics: Acetamides; Cell Differentiation; Cell Line; Dimethyl Sulfoxide; Histones; Humans; Interphase; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Macrophages; Tetradecanoylphorbol Acetate

1984
Effect of phorbol ester on differentiation of human myeloid colony forming cells (CFU-C).
    Leukemia research, 1983, Volume: 7, Issue:1

    Topics: Bone Marrow Examination; Cell Differentiation; Cells, Cultured; Colony-Stimulating Factors; Drug Synergism; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid; Phorbols; Rosette Formation; Tetradecanoylphorbol Acetate

1983
Induction of antibody-dependent and nonspecific tumor killing in human monocytic leukemia cells by nonlymphocyte factors and phorbol ester.
    Cellular immunology, 1982, Volume: 71, Issue:2

    Topics: Antibody-Dependent Cell Cytotoxicity; Cell Line; Humans; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lymphoma, Large B-Cell, Diffuse; Phagocytosis; Phorbols; Receptors, Complement; Receptors, Fc; Tetradecanoylphorbol Acetate; Urinary Bladder Neoplasms

1982
Terminal differentiation in human promyelocytic leukaemic cells in the absence of DNA synthesis.
    Nature, 1980, Mar-06, Volume: 284, Issue:5751

    Topics: Cell Differentiation; Cells, Cultured; DNA; Humans; Interphase; Leukemia, Myeloid; Phagocytosis; Phorbols; Preleukemia; Tetradecanoylphorbol Acetate

1980
Differentiation of human leukemias in response to 12-0-tetradecanoylphorbol-13-acetate in vitro.
    Blood, 1980, Volume: 55, Issue:5

    Topics: Cell Adhesion; Cell Aggregation; Cell Transformation, Neoplastic; Esterases; Humans; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Phagocytosis; Phorbols; Tetradecanoylphorbol Acetate

1980
Tumour promoters induce macrophage differentiation in human myeloid cells from patients with acute and chronic myelogenous leukaemia.
    British journal of haematology, 1981, Volume: 47, Issue:2

    Topics: Bone Marrow; Cell Differentiation; Cells, Cultured; Diterpenes; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Macrophages; Phorbols; Spleen; Tetradecanoylphorbol Acetate

1981
Terminal differentiation surface antigens of myelomonocytic cells are expressed in human promyelocytic leukemia cells (HL60) treated with chemical inducers.
    Blood, 1981, Volume: 58, Issue:4

    Topics: Animals; Antibodies, Monoclonal; Antigens, Surface; Blood Cells; Bone Marrow; Bone Marrow Cells; Cell Transformation, Neoplastic; Dimethyl Sulfoxide; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Mice; Rabbits; Tetradecanoylphorbol Acetate; Tretinoin

1981
The tumor promoter 12-O-tetradecanoyl-phorbol-13-acetate inhibits or enhances induction of differentiation of mouse myeloid leukemia cells depending on the type of serum in the medium.
    Gan, 1981, Volume: 72, Issue:2

    Topics: Animals; Cattle; Cell Differentiation; Cells, Cultured; Culture Media; Fetal Blood; Leukemia, Experimental; Leukemia, Myeloid; Mice; Phagocytes; Phorbols; Tetradecanoylphorbol Acetate

1981
Isoenzymes of lactate dehydrogenase in human leukemic cells in culture treated with inducers of differentiation.
    The Journal of cell biology, 1981, Volume: 90, Issue:2

    Topics: Acetamides; Butyrates; Cell Differentiation; Cell Line; Cell Survival; Diamines; Dimethyl Sulfoxide; Erythropoiesis; Granulocytes; Hematopoiesis; Humans; Isoenzymes; L-Lactate Dehydrogenase; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Tetradecanoylphorbol Acetate; Tretinoin

1981
Stimulation by retinoic acid of prostaglandin production and its inhibition by tumor promoters in mouse myeloid leukemia cells.
    Gan, 1981, Volume: 72, Issue:4

    Topics: Animals; Cell Line; Dinoprostone; Enzyme Induction; Indomethacin; Leukemia, Myeloid; Mice; Mice, Inbred Strains; Muramidase; Prostaglandins; Prostaglandins E; Tetradecanoylphorbol Acetate; Tretinoin

1981
Induction of maturation in cultured human monocytic leukemia cells by a phorbol diester.
    Cancer research, 1982, Volume: 42, Issue:4

    Topics: Cells, Cultured; Glucose; Humans; Leukemia, Myeloid; Muramidase; Phagocytosis; Phorbols; Rosette Formation; Tetradecanoylphorbol Acetate

1982
Modification of growth and differentiation of myeloid leukemia cells by tumor promoters.
    Carcinogenesis; a comprehensive survey, 1982, Volume: 7

    Topics: Animals; Blood; Cell Differentiation; Cell Line; Chromatography, Gel; Culture Media; Dinoprostone; Leukemia, Myeloid; Mice; Phagocytosis; Phorbols; Prostaglandins E; Tetradecanoylphorbol Acetate

1982
Generation of procoagulant activity (PCA) by phorbol-esters-induced macrophages derived from a leukemic promyelocytic cell line (HL-60).
    Blood, 1982, Volume: 59, Issue:5

    Topics: Blood Coagulation Factors; Cell Differentiation; Cell Line; Cells, Cultured; Dose-Response Relationship, Drug; Humans; Leukemia, Myeloid; Macrophages; Phorbols; Tetradecanoylphorbol Acetate

1982
Modification by serum of differentiation of cultured human myeloid leukemia cells in response to 12-O-tetradecanoylphorbol-13-acetate.
    Gan, 1982, Volume: 73, Issue:1

    Topics: Animals; Blood Physiological Phenomena; Cells, Cultured; Culture Media; Humans; Leukemia, Experimental; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Macrophages; Phorbols; Tetradecanoylphorbol Acetate

1982
Inhibition of differentiation of mouse myeloid leukemia cells by heat-stable calf serum components of very high molecular weight.
    Leukemia research, 1982, Volume: 6, Issue:5

    Topics: Animals; Blood Proteins; Cattle; Cell Differentiation; Cell Division; Cell Line; Cells, Cultured; Chromatography, Gel; Dexamethasone; Hot Temperature; Leukemia, Experimental; Leukemia, Myeloid; Mice; Molecular Weight; Phagocytosis; Tetradecanoylphorbol Acetate

1982
Enhancement of growth of a mouse macrophage cell line by a tumor promoter and granulocyte-macrophage colony-stimulating factor.
    Cancer research, 1980, Volume: 40, Issue:2

    Topics: Animals; Ascitic Fluid; Cell Division; Cell Line; Colony-Stimulating Factors; Cricetinae; Culture Media; Growth Substances; Leukemia, Myeloid; Macrophages; Phorbols; Rats; Tetradecanoylphorbol Acetate

1980
Human myelogenous leukemia: enhanced clonal proliferation in the presence of phorbol diesters.
    Blood, 1981, Volume: 57, Issue:2

    Topics: Bone Marrow Cells; Cell Division; Cell Line; Cells, Cultured; Clone Cells; Colony-Stimulating Factors; Humans; Leukemia, Myeloid; Phorbol Esters; Phorbols; Tetradecanoylphorbol Acetate

1981
Induction by tumor-promoting phorbol diester of colony-stimulating activity in human myeloid leukemia cells transformed to macrophage-mimicking cells.
    Cancer research, 1981, Volume: 41, Issue:11 Pt 1

    Topics: Bone Marrow; Cell Adhesion; Cell Division; Cell Line; Colony-Stimulating Factors; Granulocytes; Humans; Leukemia; Leukemia, Myeloid; Macrophages; Phorbols; Tetradecanoylphorbol Acetate

1981
Regulation of gene expression by tumor promoters. III. Complementation of the developmental program in myeloid leukemic cells by regulating mRNA production and mRNA translation.
    International journal of cancer, 1981, Nov-15, Volume: 28, Issue:5

    Topics: Animals; Carcinogens; Cells, Cultured; Colony-Stimulating Factors; Gene Expression Regulation; Genetic Complementation Test; In Vitro Techniques; Leukemia, Myeloid; Leukemia, Radiation-Induced; Mice; Neoplasm Proteins; Protein Biosynthesis; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate

1981
Regulation of gene expression by tumor promoters. II. Control of cell shape and developmental programs for macrophages and granulocytes in human myeloid leukemic cells.
    International journal of cancer, 1981, Sep-15, Volume: 28, Issue:3

    Topics: Carcinogens; Cell Line; Cell Transformation, Neoplastic; Colony-Stimulating Factors; Cytoplasm; Dimethyl Sulfoxide; Gene Expression Regulation; Granulocytes; Humans; Leukemia, Myeloid; Macrophages; Neoplasm Proteins; Tetradecanoylphorbol Acetate

1981
Neutrophil migration inhibition factor from T lymphocytes (NIF-T): selective removal of biologic activity by human peripheral blood neutrophils, myelocytic leukemia cells, and differentiated HL-60 cells.
    Journal of immunology (Baltimore, Md. : 1950), 1982, Volume: 128, Issue:1

    Topics: Animals; Cell Line; Cell Membrane; Cell Movement; Cell Transformation, Neoplastic; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Formaldehyde; Horses; Humans; Isoelectric Focusing; Leukemia, Myeloid; Lymphokines; Mice; Mice, Inbred Strains; Neutrophils; Rabbits; T-Lymphocytes; Tetradecanoylphorbol Acetate

1982
Regulation of growth and differentiation by phorbol esters and the mechanism of tumor promotion.
    Carcinogenesis; a comprehensive survey, 1982, Volume: 7

    Topics: Animals; Bone Marrow Cells; Cell Differentiation; Cell Line; Clone Cells; Colony-Stimulating Factors; Culture Media; Granulocytes; Humans; Leukemia, Myeloid; Macrophages; Mice; Phorbols; Tetradecanoylphorbol Acetate

1982
The effect of lentinan on production of interleukin-1 by human monocytes.
    Immunopharmacology, 1982, Volume: 5, Issue:1

    Topics: Adjuvants, Immunologic; Animals; Cell Transformation, Neoplastic; Humans; Interleukin-1; Lentinan; Leukemia, Myeloid; Lymphocyte Activation; Mice; Mice, Inbred C3H; Monocytes; Phytohemagglutinins; Polysaccharides; T-Lymphocytes; Tetradecanoylphorbol Acetate

1982
[Decrease of insulin binding to human acute leukemic cells during chemically induced differentiation].
    Bollettino della Societa italiana di biologia sperimentale, 1980, Jul-15, Volume: 56, Issue:13

    Topics: Cell Differentiation; Cell Line; Dimethyl Sulfoxide; Granulocytes; Humans; Insulin; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Macrophages; Receptor, Insulin; Tetradecanoylphorbol Acetate; Tretinoin

1980
Cell competence for industion of differentiation by insulin and other compounds in myeloid leukemic clones continuously cultured in serum-free medium.
    Blood, 1982, Volume: 60, Issue:1

    Topics: Animals; Cell Differentiation; Cell Transformation, Neoplastic; Clone Cells; Colony-Stimulating Factors; Culture Media; Dexamethasone; Hematopoietic Stem Cells; Insulin; Leukemia, Myeloid; Mice; Mice, Inbred Strains; Muramidase; Tetradecanoylphorbol Acetate; Transferrin

1982
Phorbol ester-resistant monoblastoid leukemia cells with a functional mitogen-activated protein kinase cascade but without responsive protein tyrosine phosphatases.
    Oncogene, 1995, Nov-16, Volume: 11, Issue:10

    Topics: Calcium-Calmodulin-Dependent Protein Kinases; Cell Differentiation; Cell Division; Drug Resistance, Neoplasm; Enzyme Activation; Gene Expression; Humans; Isoenzymes; Leukemia, Myeloid; Protein Kinase C; Protein Tyrosine Phosphatases; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Tumor Cells, Cultured

1995
Differential expression of c-myc, max and mxi1 in human myeloid leukemia cells during retrodifferentiation and cell death.
    Leukemia research, 1995, Volume: 19, Issue:10

    Topics: Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Basic Helix-Loop-Helix Transcription Factors; Basic-Leucine Zipper Transcription Factors; Cell Cycle; Cell Death; Cell Differentiation; DNA-Binding Proteins; Gene Expression Regulation, Leukemic; Genes, myc; Humans; Leukemia, Myeloid; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription Factors; Tumor Cells, Cultured; Tumor Suppressor Proteins

1995
Modulation of protectin (CD59 antigen) cell surface expression on human neoplastic cell lines.
    Neoplasma, 1993, Volume: 40, Issue:6

    Topics: Antigens, CD; Breast Neoplasms; Calcitriol; Carcinoma; CD59 Antigens; Cell Membrane; Cytokines; Down-Regulation; Electrophoresis, Polyacrylamide Gel; Female; Flow Cytometry; Fluorescent Antibody Technique; Glioma; Humans; Leukemia, Myeloid; Leukemia, Promyelocytic, Acute; Membrane Glycoproteins; Ovarian Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured; Up-Regulation

1993
Comparison of retinoic acid and phorbol myristate acetate as inducers of monocytic differentiation.
    International journal of cancer, 1994, Apr-01, Volume: 57, Issue:1

    Topics: CD18 Antigens; Cell Differentiation; Evaluation Studies as Topic; Gene Expression; Genes, myc; Humans; Integrins; Leukemia, Myeloid; Models, Biological; Monocytes; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-jun; Proto-Oncogene Proteins c-myb; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tretinoin; Tyrosine

1994
Growth and differentiation of the human megakaryoblastic cell line (ELF-153): a model for early stages of megakaryocytopoiesis.
    Blood, 1994, Aug-15, Volume: 84, Issue:4

    Topics: Acute Disease; Antigens, CD; Azacitidine; Cell Differentiation; Cell Division; Cell Line; Cytochalasin B; Cytokines; Fibroblast Growth Factor 2; Flow Cytometry; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoiesis; Humans; Leukemia, Myeloid; Megakaryocytes; Microscopy, Immunoelectron; Models, Biological; Receptors, Cytokine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1994
Expression of axl, a transforming receptor tyrosine kinase, in normal and malignant hematopoiesis.
    Blood, 1994, Sep-15, Volume: 84, Issue:6

    Topics: Axl Receptor Tyrosine Kinase; Base Sequence; Bone Marrow; Cell Differentiation; Flow Cytometry; Gene Expression; Hematopoiesis; Humans; Interferon-alpha; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Molecular Sequence Data; Monocytes; Myelodysplastic Syndromes; Oncogene Proteins; Polymerase Chain Reaction; Proto-Oncogene Proteins; Receptor Protein-Tyrosine Kinases; RNA-Directed DNA Polymerase; RNA, Messenger; Tetradecanoylphorbol Acetate

1994
Unassembled (soluble) vimentin in human myeloid leukemia cell line HL60.
    European journal of haematology, 1994, Volume: 53, Issue:2

    Topics: Antibodies, Monoclonal; Cell Differentiation; Desmin; Electrophoresis, Polyacrylamide Gel; Humans; Immunoblotting; Keratins; Leukemia, Myeloid; Tetradecanoylphorbol Acetate; Time Factors; Tretinoin; Tumor Cells, Cultured; Vimentin

1994
Mechanisms of beta 1 integrin-dependent adherence of granulocytic HL60 to fibronectin.
    Journal of leukocyte biology, 1995, Volume: 57, Issue:4

    Topics: Actins; Adult; Cell Adhesion; Cell Differentiation; Complement C5a; Cytochalasin B; Cytoskeleton; Epitopes; Fibronectins; Granulocytes; Humans; Integrin beta1; Integrins; Leukemia, Myeloid; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Up-Regulation

1995
Expression and regulation of aromatase cytochrome P450 in THP 1 human myeloid leukaemia cells.
    Molecular and cellular endocrinology, 1995, Apr-28, Volume: 110, Issue:1-2

    Topics: Androstenedione; Aromatase; Base Sequence; Calcitriol; Cell Differentiation; Dexamethasone; Estradiol; Exons; Gene Expression Regulation, Neoplastic; Humans; Leukemia, Myeloid; Molecular Sequence Data; Polymerase Chain Reaction; RNA Splicing; RNA-Directed DNA Polymerase; RNA, Messenger; Testosterone; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1995
Fas receptor (CD95)-mediated apoptosis is induced in leukemic cells entering G1B compartment of the cell cycle.
    Blood, 1995, Nov-15, Volume: 86, Issue:10

    Topics: Acute Disease; Antibodies, Monoclonal; Apoptosis; Cell Division; Child; Child, Preschool; DNA Damage; DNA, Neoplasm; fas Receptor; Fluorouracil; G1 Phase; Humans; Leukemia, Myeloid; Neoplastic Stem Cells; RNA, Neoplasm; Signal Transduction; Tetradecanoylphorbol Acetate; Thymidine; Tumor Cells, Cultured

1995
Inhibition of leukemic cell growth by the protein kinase C activator bryostatin 1 correlates with the dephosphorylation of cyclin-dependent kinase 2.
    Cancer research, 1995, Sep-01, Volume: 55, Issue:17

    Topics: Antineoplastic Agents; Base Sequence; Blotting, Western; Bryostatins; CDC2-CDC28 Kinases; Cell Division; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinases; Cyclins; Humans; Lactones; Leukemia, Myeloid; Macrolides; Molecular Sequence Data; Phosphorylation; Polymerase Chain Reaction; Protein Serine-Threonine Kinases; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured

1995
MCL1, a gene expressed in programmed myeloid cell differentiation, has sequence similarity to BCL2.
    Proceedings of the National Academy of Sciences of the United States of America, 1993, Apr-15, Volume: 90, Issue:8

    Topics: Amino Acid Sequence; Base Sequence; Cell Differentiation; Cloning, Molecular; DNA, Neoplasm; Gene Expression; Humans; Kinetics; Leukemia, Myeloid; Molecular Sequence Data; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; Poly A; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogenes; RNA; RNA, Messenger; Sequence Homology, Amino Acid; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1993
Induction of transforming growth factor beta 1 and its receptor expression during myeloid leukemia cell differentiation.
    Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1994, Volume: 5, Issue:12

    Topics: Amino Acid Sequence; Animals; Antibodies; Base Sequence; Cell Differentiation; Cell Line; Cloning, Molecular; DNA Primers; Fibrosarcoma; Gene Expression; Humans; Kinetics; Leukemia, Myeloid; Leukemia, Promyelocytic, Acute; Lung; Mink; Molecular Sequence Data; Polymerase Chain Reaction; Receptors, Transforming Growth Factor beta; Recombinant Fusion Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Transforming Growth Factor beta; Tretinoin; Tumor Cells, Cultured

1994
Transcriptional regulation of the vacuolar H(+)-ATPase B2 subunit gene in differentiating THP-1 cells.
    The Journal of biological chemistry, 1995, Mar-31, Volume: 270, Issue:13

    Topics: Base Sequence; Binding Sites; Cell Differentiation; Cell Line; Cells, Cultured; Deoxyribonuclease I; DNA Probes; DNA-Binding Proteins; Exons; Gene Expression Regulation, Enzymologic; Humans; Leukemia, Myeloid; Macromolecular Substances; Macrophages; Molecular Sequence Data; Monocytes; Promoter Regions, Genetic; Proton-Translocating ATPases; Restriction Mapping; RNA, Messenger; Sp1 Transcription Factor; Tetradecanoylphorbol Acetate; Transcription Factor AP-2; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured; Vacuoles

1995
Okadaic acid increased annexin I and induced differentiation of human promyelocytic leukemia cells.
    Biochimica et biophysica acta, 1995, Apr-06, Volume: 1266, Issue:1

    Topics: Annexin A1; Cell Adhesion; Cell Differentiation; Cell Division; Cell Line; Ethers, Cyclic; Humans; Leukemia, Myeloid; Okadaic Acid; Phosphorylation; RNA, Messenger; Tetradecanoylphorbol Acetate

1995
Characterization of human TUR leukemia cells: continued cell cycle progression in the presence of phorbol ester is associated with resistance to apoptosis.
    European journal of cell biology, 1994, Volume: 65, Issue:2

    Topics: Apoptosis; Cell Cycle; Cell Differentiation; Cell Division; Drug Resistance; Humans; Leukemia, Myeloid; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1994
Upregulation of p21 RAS levels in HL-60 cells during differentiation induction with DMSO, all-trans-retinoic acid and TPA.
    Leukemia research, 1995, Volume: 19, Issue:4

    Topics: Cell Cycle; Cell Differentiation; Cell Division; Cell Line; Dimethyl Sulfoxide; Genes, ras; Hematopoiesis; Humans; Leukemia, Myeloid; Proto-Oncogene Proteins p21(ras); Tetradecanoylphorbol Acetate; Tretinoin

1995
Repressor activity of CCAAT displacement protein in HL-60 myeloid leukemia cells.
    The Journal of biological chemistry, 1995, May-26, Volume: 270, Issue:21

    Topics: 3T3 Cells; Animals; Binding Sites; Cell Differentiation; Dimethyl Sulfoxide; Dimethylformamide; DNA, Recombinant; Gene Expression Regulation, Neoplastic; Globins; Homeodomain Proteins; Humans; Leukemia, Myeloid; Macrophages; Membrane Glycoproteins; Mice; NADPH Oxidase 2; NADPH Oxidases; Neutrophils; Nuclear Proteins; Promoter Regions, Genetic; Protein Binding; Repressor Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription Factors; Transformation, Genetic; Tretinoin; Tumor Cells, Cultured

1995
Immunomodulatory effect of sodium dodecyl sulfate on human neutrophils and the human promyelocytic HL-60 cell line.
    European journal of pharmacology, 1994, Aug-03, Volume: 270, Issue:4

    Topics: Adjuvants, Immunologic; Cell Division; Glucuronidase; Humans; Leukemia, Myeloid; Lysosomes; Neutrophils; Peroxidase; Respiratory Burst; Sodium Dodecyl Sulfate; Superoxides; Tetradecanoylphorbol Acetate; Thymidine; Tumor Cells, Cultured

1994
Regulation of CD9 expression during 12-O-tetradecanoyl-phorbol-13-acetate- induced differentiation of human myeloid leukemia (HL-60) cells.
    Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1994, Volume: 5, Issue:11

    Topics: Antigens, CD; Base Sequence; Biomarkers, Tumor; Cell Differentiation; Cycloheximide; Dactinomycin; DNA, Neoplasm; Humans; Leukemia, Myeloid; Membrane Glycoproteins; Methylation; Molecular Sequence Data; RNA, Messenger; Tetradecanoylphorbol Acetate; Tetraspanin 29; Transcription, Genetic; Transcriptional Activation; Tumor Cells, Cultured

1994
Changes in expression of the cell adhesion molecule PECAM-1 (CD31) during differentiation of human leukemic cell lines.
    Tissue antigens, 1994, Volume: 44, Issue:5

    Topics: Antigens, Differentiation, Myelomonocytic; Blotting, Northern; Cell Adhesion Molecules; Cell Differentiation; Cell Line; Electrophoresis, Polyacrylamide Gel; Humans; Leukemia, Myeloid; Leukocytes, Mononuclear; Microscopy, Fluorescence; Platelet Endothelial Cell Adhesion Molecule-1; RNA, Messenger; Tetradecanoylphorbol Acetate; Up-Regulation

1994
Differential regulation of interleukin-12 (IL-12), tumor necrosis factor alpha, and IL-1 beta production in human myeloid leukemia cell lines and peripheral blood mononuclear cells.
    Blood, 1994, Apr-01, Volume: 83, Issue:7

    Topics: Animals; CHO Cells; Cricetinae; Dexamethasone; Dimethyl Sulfoxide; Humans; Interferon-gamma; Interleukin-1; Interleukin-10; Interleukin-12; Interleukins; Leukemia, Myeloid; Leukocytes, Mononuclear; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

1994
Role of cell surface O-linked oligosaccharides in adhesion of HL60 cells to fibronectin: regulation of integrin-dependent cell adhesion by O-linked oligosaccharide elongation.
    Experimental cell research, 1994, Volume: 214, Issue:2

    Topics: Acetylgalactosamine; Antigens, CD; Benzyl Compounds; Cell Adhesion; Cell Membrane; Fibronectins; Glycoproteins; Humans; Integrins; Leukemia, Myeloid; Leukocytes; Leukosialin; Oligosaccharides; Sialoglycoproteins; Swainsonine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1994
Myeloid activation antigen CD66/67: immunochemical and immunocytometric characterization with the Vth workshop monoclonal antibodies.
    Neoplasma, 1994, Volume: 41, Issue:3

    Topics: Antibodies, Monoclonal; Antigens, CD; Antigens, Differentiation; Antigens, Neoplasm; Cell Adhesion Molecules; Down-Regulation; Flow Cytometry; Fluorometry; Hematopoietic System; Humans; Immunohistochemistry; Leukemia, Myeloid; Membrane Glycoproteins; Molecular Weight; Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1994
Regulation of the human cellular glutathione peroxidase gene during in vitro myeloid and monocytic differentiation.
    Blood, 1994, Dec-01, Volume: 84, Issue:11

    Topics: Cell Differentiation; Dimethylformamide; Enzyme Induction; Gene Expression Regulation, Neoplastic; Glutathione Peroxidase; Granulocytes; Humans; Leukemia, Myeloid; Leukemia, Promyelocytic, Acute; Membrane Glycoproteins; Monocytes; NADPH Oxidase 2; NADPH Oxidases; Neoplasm Proteins; Phagocytes; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1994
Different regulation of plasminogen activator inhibitor 2 gene expression by phorbol ester and cAMP in human myeloid leukemia cell line PL-21.
    Thrombosis and haemostasis, 1994, Volume: 72, Issue:1

    Topics: Bucladesine; Cycloheximide; Gene Expression Regulation, Neoplastic; Humans; Leukemia, Myeloid; Plasminogen Activator Inhibitor 2; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured

1994
1-beta-D-arabinofuranosylcytosine activates serine/threonine protein kinases and c-jun gene expression in phorbol ester-resistant myeloid leukemia cells.
    Molecular pharmacology, 1994, Volume: 46, Issue:1

    Topics: Cytarabine; Drug Resistance; Enzyme Activation; Gene Expression Regulation; Genes, jun; Humans; Leukemia, Myeloid; Protein Serine-Threonine Kinases; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1994
Crocidolite asbestos increased 8-hydroxydeoxyguanosine levels in cellular DNA of a human promyelocytic leukemia cell line, HL60.
    Carcinogenesis, 1994, Volume: 15, Issue:4

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Asbestos, Crocidolite; Catalase; Cell Differentiation; Cytochalasin B; Deoxyguanosine; DNA Damage; DNA, Neoplasm; Humans; In Vitro Techniques; Leukemia, Myeloid; Reactive Oxygen Species; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1994
High-dose mitoxantrone induces programmed cell death or apoptosis in human myeloid leukemia cells.
    Blood, 1993, Nov-15, Volume: 82, Issue:10

    Topics: Apoptosis; Cytarabine; DNA; Dose-Response Relationship, Drug; Genes, jun; Genes, myc; Humans; Leukemia, Myeloid; Mitoxantrone; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1993
Expression and modulation of annexin VIII in human leukemia-lymphoma cell lines.
    Leukemia research, 1993, Volume: 17, Issue:11

    Topics: Annexins; Blotting, Northern; Bryostatins; Cell Differentiation; Cholecalciferol; Dactinomycin; Gene Expression Regulation, Neoplastic; Half-Life; Humans; Lactones; Leukemia; Leukemia, Myeloid; Leukemia, Promyelocytic, Acute; Lymphoma; Macrolides; RNA, Messenger; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured

1993
Down-regulation of c-myc gene is not obligatory for growth inhibition and differentiation of human myeloid leukemia cells.
    Leukemia, 1993, Volume: 7, Issue:11

    Topics: Cell Differentiation; Cell Division; Cytarabine; Down-Regulation; Erythrocytes; Gene Expression Regulation, Leukemic; Genes, myc; Humans; Hydroxyurea; Interferon-alpha; Leukemia, Myeloid; Macrophages; Megakaryocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1993
Expression of protein kinase C isoforms in HL60 and phorbol ester resistant HL525 cells.
    Cytobios, 1993, Volume: 76, Issue:304

    Topics: Blotting, Western; Down-Regulation; Drug Resistance; Humans; Isomerism; Leukemia, Experimental; Leukemia, Myeloid; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1993
Interactions of promonocytic U937 cells with proteins of the extracellular matrix.
    Immunology, 1993, Volume: 80, Issue:2

    Topics: Cell Adhesion; Cell Differentiation; Collagen; Drug Combinations; Extracellular Matrix Proteins; Fibronectins; Humans; Integrins; Laminin; Leukemia, Myeloid; Monocytes; Peptides; Proteoglycans; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1993
Activation of Raf-1 and mitogen-activated protein kinases during monocytic differentiation of human myeloid leukemia cells.
    The Journal of biological chemistry, 1994, Jan-14, Volume: 269, Issue:2

    Topics: Amino Acid Sequence; Calcium-Calmodulin-Dependent Protein Kinases; Cell Differentiation; Enzyme Activation; Ethers, Cyclic; Gene Expression; Genes, jun; Humans; In Vitro Techniques; Leukemia, Myeloid; Molecular Sequence Data; Monocytes; Okadaic Acid; Protein Kinase C; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; RNA, Messenger; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured

1994
A role for oxygen radicals in rat monocytic leukemia cell differentiation under stimulation with platelet-activating factor.
    Biochimica et biophysica acta, 1994, Feb-17, Volume: 1220, Issue:3

    Topics: Animals; Catalase; Cell Differentiation; Cell Line; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Kinetics; Leukemia, Experimental; Leukemia, Myeloid; Mannitol; Platelet Activating Factor; Rats; Rats, Inbred Strains; Superoxide Dismutase; Superoxides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1994
Increment of the cyclin D1 mRNA level in TPA-treated three human myeloid leukemia cell lines: HEL, CMK and HL-60 cells.
    Biochemical and biophysical research communications, 1993, Sep-15, Volume: 195, Issue:2

    Topics: Base Sequence; Blotting, Northern; Cell Cycle; Cell Division; Cloning, Molecular; Cyclin D1; Cyclins; Dimethyl Sulfoxide; Esophageal Neoplasms; Humans; Kinetics; Leukemia, Myeloid; Molecular Sequence Data; Molecular Weight; Oligonucleotide Probes; Oncogene Proteins; Open Reading Frames; Polymerase Chain Reaction; RNA, Messenger; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured

1993
Microinjected catalytic subunit of cAMP-dependent protein kinase induces apoptosis in myeloid leukemia (IPC-81) cells.
    Experimental cell research, 1993, Volume: 206, Issue:1

    Topics: Animals; Apoptosis; Leukemia, Experimental; Leukemia, Myeloid; Marine Toxins; Microcystins; Microinjections; Peptides, Cyclic; Phenotype; Phosphoprotein Phosphatases; Protein Kinases; Protein Phosphatase 1; Rats; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1993
Novel fluoride-stimulated dichlorofluorescin dye oxidation pathway in human leukemia cell lines.
    Biochemical and biophysical research communications, 1993, Jul-30, Volume: 194, Issue:2

    Topics: Cell Cycle; Cell Differentiation; Dimethylformamide; Flow Cytometry; Fluoresceins; Humans; Hydrogen Peroxide; Kinetics; Leukemia, Myeloid; Leukemia, Promyelocytic, Acute; Oxidation-Reduction; Sodium Fluoride; Superoxides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1993
Chronic human immunodeficiency virus type 1 infection stimulates distinct NF-kappa B/rel DNA binding activities in myelomonoblastic cells.
    Journal of virology, 1993, Volume: 67, Issue:9

    Topics: Base Sequence; Binding Sites; Cell Differentiation; DNA-Binding Proteins; Enhancer Elements, Genetic; Gene Expression Regulation, Viral; Genes, fms; HIV-1; Humans; Interferon-beta; Leukemia, Myeloid; Molecular Sequence Data; Monocytes; NF-kappa B; Oligodeoxyribonucleotides; Parainfluenza Virus 1, Human; Promoter Regions, Genetic; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-rel; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

1993
Differential modulation of the expression of the intermediate filament proteins vimentin and nuclear lamins A and C by differentiation inducers in human myeloid leukemia (U-937, HL-60) cells.
    Experimental cell research, 1993, Volume: 208, Issue:1

    Topics: Bucladesine; Butyrates; Butyric Acid; Cell Differentiation; Cytarabine; Gene Expression; Humans; In Vitro Techniques; Lamins; Leukemia, Myeloid; Nuclear Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured; Vimentin

1993
Phorbol myristate acetate-differentiated THP-1 cells display increased levels of MHC class I and class II mRNA and interferon-gamma-inducible tumoricidal activity.
    Oncology research, 1993, Volume: 5, Issue:1

    Topics: Antigens, Neoplasm; Cell Adhesion; Cell Differentiation; Histocompatibility Antigens Class I; Histocompatibility Antigens Class II; Humans; Interferon-gamma; Interleukin-1; Leukemia, Myeloid; Macrophages; Phagocytosis; Recombinant Proteins; RNA, Messenger; Superoxides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1993
Resistance to phorbol ester-induced differentiation of a U-937 myeloid leukemia cell variant with a signaling defect upstream to Raf-1 kinase.
    Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1993, Volume: 4, Issue:8

    Topics: Cell Differentiation; Drug Resistance; Humans; Leukemia, Myeloid; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1993
Retinoic acid potentiates phorbol ester-mediated induction of urokinase and plasminogen activator inhibitor type 2 in human myeloid leukemic cell lines.
    Endocrinology, 1993, Volume: 133, Issue:4

    Topics: Drug Synergism; Enzyme Induction; Humans; Leukemia, Myeloid; Plasminogen Activator Inhibitor 2; Plasminogen Activators; Receptors, Cell Surface; Receptors, Urokinase Plasminogen Activator; RNA, Messenger; Templates, Genetic; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured; Urokinase-Type Plasminogen Activator

1993
Protooncogene junB as a target for activin actions.
    Endocrinology, 1993, Volume: 133, Issue:5

    Topics: Activins; Animals; Drug Synergism; Gene Expression Regulation, Neoplastic; Genes, Immediate-Early; Genes, jun; Humans; Inhibins; Kinetics; Leukemia, Myeloid; PC12 Cells; Protein Kinase C; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1993
Differentiation-linked expression of prothymosin alpha gene in human myeloid leukemic cells.
    Experimental cell research, 1993, Volume: 204, Issue:1

    Topics: Cell Differentiation; Down-Regulation; Humans; Hydroxyurea; Leukemia, Myeloid; Protein Precursors; RNA, Messenger; Tetradecanoylphorbol Acetate; Thymosin; Tretinoin; Tumor Cells, Cultured; Up-Regulation

1993
Co-purification of mitogen-activated protein kinases with phorbol ester-induced c-Jun kinase activity in U937 leukaemic cells.
    Oncogene, 1993, Volume: 8, Issue:2

    Topics: Base Sequence; Humans; Leukemia, Myeloid; Mitogen-Activated Protein Kinase 1; Molecular Sequence Data; Phosphorylation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-jun; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1993
Differentiation-stage specific self-peptides bound by major histocompatibility complex class I molecules.
    The Journal of experimental medicine, 1993, Mar-01, Volume: 177, Issue:3

    Topics: Amino Acid Sequence; Cell Differentiation; Cell Transformation, Neoplastic; Chromatography, High Pressure Liquid; Flow Cytometry; Fluorescent Antibody Technique; Histocompatibility Antigens Class I; Humans; Leukemia, Myeloid; Major Histocompatibility Complex; Molecular Sequence Data; Peptides; Phenotype; Precipitin Tests; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1993
Differentiation-associated expression of prostaglandin G/H synthase in monocytic cells.
    FEBS letters, 1993, Mar-29, Volume: 320, Issue:1

    Topics: Animals; Cell Differentiation; Dexamethasone; Gene Expression Regulation, Enzymologic; Humans; Leukemia, Myeloid; Mice; Monocytes; Prostaglandin-Endoperoxide Synthases; RNA, Messenger; Sheep; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1993
Phorbol ester-induced monocytic differentiation is associated with G2 delay and down-regulation of cdc25 expression.
    Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1993, Volume: 4, Issue:3

    Topics: Base Sequence; Cell Differentiation; Down-Regulation; G2 Phase; Gene Expression; Humans; Leukemia, Myeloid; Molecular Sequence Data; Monocytes; S Phase; Tetradecanoylphorbol Acetate; Time Factors

1993
Characterization of acute myeloid leukemia (AML) coexpressing lymphoid markers: different biologic features between T-cell antigen positive and B-cell antigen positive AML.
    Leukemia, 1993, Volume: 7, Issue:5

    Topics: Acute Disease; Adolescent; Adult; Antigens, CD; Antigens, Differentiation, B-Lymphocyte; Antigens, Differentiation, T-Lymphocyte; Cell Differentiation; Child; Child, Preschool; Chromosome Banding; DNA, Neoplasm; Female; Gene Rearrangement; Genes, Immunoglobulin; Humans; Immunophenotyping; In Vitro Techniques; Infant; Leukemia, Myeloid; Male; Middle Aged; Prognosis; Receptors, Antigen, T-Cell, alpha-beta; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1993
Tissue factor and plasminogen activator inhibitor expression in the differentiation of myeloid leukemic cells.
    Leukemia, 1993, Volume: 7, Issue:6

    Topics: Cell Differentiation; Gene Expression; Hematopoiesis; Humans; In Vitro Techniques; Leukemia, Myeloid; Plasminogen Activator Inhibitor 1; Plasminogen Activator Inhibitor 2; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Thromboplastin; Tumor Cells, Cultured

1993
Altered cytoplasmic/nuclear distribution of the c-myc protein in differentiating ML-1 human myeloid leukemia cells.
    Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1993, Volume: 4, Issue:5

    Topics: Cell Differentiation; Cell Nucleus; Cytoplasm; Humans; Leukemia, Myeloid; Nuclear Proteins; Proto-Oncogene Proteins c-myc; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1993
Expression and regulation of aromatase and 17 beta-hydroxysteroid dehydrogenase type 4 in human THP 1 leukemia cells.
    The Journal of steroid biochemistry and molecular biology, 1995, Volume: 55, Issue:5-6

    Topics: Actins; Aromatase; Cell Differentiation; Dexamethasone; Estradiol Dehydrogenases; Gene Expression Regulation, Enzymologic; Humans; Leukemia, Myeloid; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1995
Long-wave ultraviolet radiation causes increase of membrane-bound fraction of protein kinase C in rat myeloid leukemia cells.
    Photodermatology, photoimmunology & photomedicine, 1995, Volume: 11, Issue:3

    Topics: Animals; Apoptosis; Cell Count; Cell Cycle; Cell Division; Cell Survival; Coloring Agents; Flow Cytometry; Leukemia, Experimental; Leukemia, Myeloid; Membrane Proteins; Propidium; Protein Kinase C; Radiation Dosage; Rats; Tetradecanoylphorbol Acetate; Time Factors; Tritium; Trypan Blue; Tumor Cells, Cultured; Ultraviolet Rays

1995
DNA triplex formation selectively inhibits granulocyte-macrophage colony-stimulating factor gene expression in human T cells.
    The Journal of biological chemistry, 1996, Jun-14, Volume: 271, Issue:24

    Topics: Base Sequence; Binding Sites; Cell Line; Deoxyribonuclease I; DNA; Gene Products, tax; Granulocyte-Macrophage Colony-Stimulating Factor; Human T-lymphotropic virus 1; Humans; Leukemia, Myeloid; Luciferases; Molecular Sequence Data; NF-kappa B; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Promoter Regions, Genetic; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured

1996
Dual effect of 1 alpha,25-dihydroxyvitamin D3 on hsp28 and PKC beta gene expression in phorbol ester-resistant human myeloid HL-525 leukemic cells.
    Biochemical pharmacology, 1996, Jul-26, Volume: 52, Issue:2

    Topics: Calcitriol; Gene Expression Regulation; Heat-Shock Proteins; HSP30 Heat-Shock Proteins; Humans; Leukemia, Myeloid; Membrane Proteins; Protein Kinase C; Protein Kinase C beta; Receptors, Calcitriol; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1996
A cardiotonic steroid bufalin-induced differentiation of THP-1 cells. Involvement of Na+, K(+)-ATPase inhibition in the early changes in proto-oncogene expression.
    Biochemical pharmacology, 1996, Jul-26, Volume: 52, Issue:2

    Topics: Bufanolides; Cardiotonic Agents; Cell Differentiation; Gene Expression Regulation; Humans; Leukemia, Myeloid; Proto-Oncogene Mas; Proto-Oncogene Proteins; Sodium-Potassium-Exchanging ATPase; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1996
Stimulation of granulocyte-macrophage colony-stimulating factor (GM-CSF) production and its role as an autocrine inducer of CD14 upregulation in human myeloid leukemia cells.
    Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, 1996, Volume: 16, Issue:6

    Topics: Calcimycin; Cell Differentiation; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-1; Ionophores; Leukemia, Myeloid; Lipopolysaccharide Receptors; Recombinant Proteins; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Up-Regulation

1996
Co-ordinated downregulation of bcl-2 and bax expression during granulocytic and macrophage-like differentiation of the HL60 promyelocytic leukaemia cell line.
    FEBS letters, 1996, Oct-07, Volume: 394, Issue:3

    Topics: Apoptosis; bcl-2-Associated X Protein; Cell Differentiation; Down-Regulation; Gene Expression Regulation, Developmental; Granulocytes; HL-60 Cells; Humans; Leukemia, Myeloid; Macrophages; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; RNA Splicing; RNA, Messenger; Tetradecanoylphorbol Acetate; Tretinoin

1996
A variant CD30 protein lacking extracellular and transmembrane domains is induced in HL-60 by tetradecanoylphorbol acetate and is expressed in alveolar macrophages.
    Blood, 1996, Oct-01, Volume: 88, Issue:7

    Topics: Animals; Base Sequence; Bronchoalveolar Lavage Fluid; Cloning, Molecular; COS Cells; DNA, Complementary; Gene Expression Regulation, Leukemic; HL-60 Cells; Humans; Immune Sera; Ki-1 Antigen; Leukemia, Myeloid; Macrophages, Alveolar; Molecular Sequence Data; Multigene Family; Neoplasm Proteins; NF-kappa B; Phosphorylation; Promoter Regions, Genetic; Protein Processing, Post-Translational; Protein Structure, Tertiary; Rabbits; Recombinant Fusion Proteins; RNA Splicing; RNA, Messenger; RNA, Neoplasm; Signal Transduction; Sjogren's Syndrome; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Tumor Cells, Cultured

1996
Transcriptional control of the heme oxygenase gene in mouse M1 cells during their TPA-induced differentiation into macrophages.
    Journal of cellular biochemistry, 1996, Sep-01, Volume: 62, Issue:3

    Topics: Acetylcysteine; Animals; Binding Sites; Carcinogens; Cell Differentiation; Electrophoresis; Enzyme Inhibitors; Free Radical Scavengers; Gene Expression Regulation, Neoplastic; Genes, fos; Genes, jun; Heme Oxygenase (Decyclizing); Hydrogen Peroxide; Indoles; Leukemia, Myeloid; Macrophages; Maleimides; Mice; NF-kappa B; Nuclear Proteins; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription, Genetic; Tumor Cells, Cultured

1996
The effects of the broadband UVA radiation on myeloid leukemia cells: the possible role of protein kinase C in mediation of UVA-induced effects.
    Photochemistry and photobiology, 1996, Volume: 64, Issue:6

    Topics: Animals; Apoptosis; Cell Division; Isoenzymes; Leukemia, Myeloid; Major Histocompatibility Complex; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Ultraviolet Rays

1996
Bone marrow fibroblast exposure to the inflammatory cytokines tumor necrosis factor-alpha and interferon-gamma increases adhesion of acute myeloid leukemia cells and alters the adhesive mechanism.
    Experimental hematology, 1997, Volume: 25, Issue:2

    Topics: Acute Disease; Antibodies, Monoclonal; Antigens, CD; Apoptosis; Bone Marrow; Bone Marrow Cells; Cell Adhesion; Cell Adhesion Molecules; Cells, Cultured; Cytokines; Drug Synergism; Fibroblasts; Humans; Integrin alpha4; Integrin beta Chains; Integrins; Intercellular Adhesion Molecule-1; Interferon-alpha; Interferon-gamma; Leukemia, Myeloid; Neoplasm Proteins; Neoplastic Stem Cells; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Vascular Cell Adhesion Molecule-1

1997
Differentiating agents modulate topoisomerase I activity in U-937 promonocytic cells.
    European journal of pharmacology, 1997, Apr-11, Volume: 324, Issue:1

    Topics: Acetamides; Antineoplastic Agents; Blotting, Northern; Blotting, Western; Carcinogens; Cell Transformation, Neoplastic; DNA Topoisomerases, Type I; Electrophoresis, Polyacrylamide Gel; Humans; Leukemia, Myeloid; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tretinoin; Tumor Cells, Cultured

1997
Ectopic expression of 2-5A synthetase in myeloid cells induces growth arrest and facilitates the appearance of a myeloid differentiation marker.
    Cancer research, 1997, Jul-01, Volume: 57, Issue:13

    Topics: 2',5'-Oligoadenylate Synthetase; Cell Differentiation; Cell Division; Chlorides; Dimethyl Sulfoxide; Granulocytes; HL-60 Cells; Humans; Interferon-beta; Leukemia, Myeloid; Macrophages; Proto-Oncogene Proteins c-myc; Retinoblastoma Protein; Tetradecanoylphorbol Acetate; Time Factors; Transfection; Tumor Cells, Cultured; Zinc Compounds

1997
Induction of apoptosis and potentiation of TNF- and Fas-mediated apoptosis in U937 cells by the xanthogenate compound D609.
    Experimental cell research, 1997, Aug-25, Volume: 235, Issue:1

    Topics: Antibodies, Monoclonal; Antigens, CD; Antineoplastic Agents; Apoptosis; Arachidonic Acid; Bridged-Ring Compounds; Chromatin; Culture Media, Serum-Free; DNA Fragmentation; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; fas Receptor; Humans; Kinetics; Leukemia, Myeloid; Norbornanes; Nucleosomes; Recombinant Proteins; Sphingomyelin Phosphodiesterase; Sphingosine; Tetradecanoylphorbol Acetate; Thiocarbamates; Thiones; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

1997
Differential effects of phorbol ester on signaling and gene expression in human leukemia cells.
    Leukemia research, 1997, Volume: 21, Issue:7

    Topics: Cell Differentiation; Cell Division; Cytosol; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Genes, fms; Genes, jun; Genes, myc; Humans; Kinetics; Leukemia, Myeloid; Monocytes; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured

1997
Aggressive tumor growth of human TUR leukemia cells is associated with high levels of c-myc expression and down-regulation of p20-max.
    International journal of cancer, 1997, Sep-17, Volume: 72, Issue:6

    Topics: Animals; Clone Cells; Female; Gene Expression Regulation, Neoplastic; Genes, myc; Humans; Karyotyping; Leukemia, Myeloid; Lymphoma, Large B-Cell, Diffuse; Mice; Mice, SCID; Naphthol AS D Esterase; Proto-Oncogene Proteins c-myc; Superoxides; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transplantation, Heterologous; Tumor Cells, Cultured

1997
Redundant functions of B-Myb and c-Myb in differentiating myeloid cells.
    Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1997, Volume: 8, Issue:12

    Topics: Antigens, Differentiation; Blotting, Western; Cell Cycle; Cell Cycle Proteins; Cell Differentiation; Cell Division; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA-Binding Proteins; Gene Expression Regulation; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukemia, Myeloid; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myb; Tetradecanoylphorbol Acetate; Trans-Activators; Transcription Factors; Transfection; Tumor Cells, Cultured

1997
Transcriptional regulation of urokinase-type plasminogen activator receptor by cyclic AMP in PL-21 human myeloid leukemia cells: comparison with the regulation by phorbol myristate acetate.
    Thrombosis and haemostasis, 1998, Volume: 79, Issue:3

    Topics: Carcinogens; Cyclic AMP; Humans; Leukemia, Myeloid; Receptors, Cell Surface; Receptors, Urokinase Plasminogen Activator; Signal Transduction; Tetradecanoylphorbol Acetate; Transcriptional Activation; Tumor Cells, Cultured

1998
Evidence of a functional role for the cyclin-dependent kinase inhibitor p21(WAF1/CIP1/MDA6) in the reciprocal regulation of PKC activator-induced apoptosis and differentation in human myelomonocytic leukemia cells.
    Experimental cell research, 1998, Oct-10, Volume: 244, Issue:1

    Topics: Apoptosis; Bryostatins; Cell Differentiation; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Enzyme Activation; G1 Phase; Humans; Lactones; Leukemia, Myeloid; Macrolides; Protein Kinase C; Tetradecanoylphorbol Acetate; U937 Cells

1998
Correlation of Pit-1 gene expression and Pit-1 content with proliferation and differentiation in human myeloid leukemic cells.
    Experimental cell research, 1998, Nov-25, Volume: 245, Issue:1

    Topics: Cell Differentiation; Cell Division; DNA-Binding Proteins; Gene Expression; HL-60 Cells; Homeodomain Proteins; Humans; Interferon-gamma; Leukemia, Myeloid; Mitogens; Tetradecanoylphorbol Acetate; Transcription Factor Pit-1; Transcription Factors; Tumor Cells, Cultured

1998
Tyrosine phosphorylation of proteins in primary human myeloid leukemia cells stimulated by cytokines: analysis of the frequency of phosphorylation, and partial identification and semi-quantification of signaling molecules.
    International journal of hematology, 1998, Volume: 68, Issue:4

    Topics: Acute Disease; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Cytokines; DNA-Binding Proteins; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic Stem Cells; Humans; Interleukin-3; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid; Milk Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Biosynthesis; Protein-Tyrosine Kinases; Proteins; Signal Transduction; STAT5 Transcription Factor; Tetradecanoylphorbol Acetate; Thrombopoietin; Trans-Activators; Tumor Necrosis Factor-alpha

1998
Differential expression and phosphorylation of CTCF, a c-myc transcriptional regulator, during differentiation of human myeloid cells.
    FEBS letters, 1999, Feb-05, Volume: 444, Issue:1

    Topics: Blotting, Northern; Blotting, Western; Burkitt Lymphoma; CCCTC-Binding Factor; Cell Differentiation; Cytarabine; Dimethyl Sulfoxide; DNA-Binding Proteins; Down-Regulation; Erythrocytes; Gene Expression Regulation; Humans; Isoelectric Focusing; Leukemia, Myeloid; Leukocytes; Megakaryocytes; Phosphorylation; Proto-Oncogene Proteins c-myc; Repressor Proteins; RNA Processing, Post-Transcriptional; Staurosporine; Tetradecanoylphorbol Acetate; Transcription Factors; Tretinoin; Tumor Cells, Cultured

1999
Arsenic trioxide induces apoptosis of myeloid leukemia cells by activation of caspases.
    Medical oncology (Northwood, London, England), 1999, Volume: 16, Issue:1

    Topics: Amino Acid Chloromethyl Ketones; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Caspase Inhibitors; Caspases; Enzyme Activation; Etoposide; Humans; Leukemia, Myeloid; Oxides; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1999
Expression of the 67-kDa laminin receptor in acute myeloid leukemia cells mediates adhesion to laminin and is frequently associated with monocytic differentiation.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1999, Volume: 5, Issue:6

    Topics: Acute Disease; Adolescent; Adult; Aged; Antigens, CD; Blotting, Western; Cell Adhesion; Cell Differentiation; Cells, Cultured; Female; HL-60 Cells; Humans; Immunophenotyping; Laminin; Leukemia, Myeloid; Male; Middle Aged; Monocytes; Prognosis; Receptors, Laminin; Survival Rate; Tetradecanoylphorbol Acetate; Tretinoin

1999
Mitogen-activated protein kinase pathway is dispensable for microtubule-active drug-induced Raf-1/Bcl-2 phosphorylation and apoptosis in leukemia cells.
    Leukemia, 1999, Volume: 13, Issue:7

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Calcium-Calmodulin-Dependent Protein Kinases; Genes, ras; Humans; Leukemia, Myeloid; MAP Kinase Kinase Kinase 1; Microtubules; Paclitaxel; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-raf; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1999
Modulation of CXCR4 expression and SDF-1alpha functional activity during differentiation of human monocytes and macrophages.
    Journal of leukocyte biology, 1999, Volume: 66, Issue:1

    Topics: Cell Differentiation; Cell Line; Chemokine CXCL12; Chemokines, CXC; Gene Expression Regulation; Granulocyte-Macrophage Colony-Stimulating Factor; HL-60 Cells; Humans; K562 Cells; Leukemia, Myeloid; Lipoproteins, LDL; Macrophages; Mitogens; Monocytes; Receptors, CXCR4; Tetradecanoylphorbol Acetate; Time Factors; Transcription, Genetic; U937 Cells; Up-Regulation

1999
Ap4A induces apoptosis in human cultured cells.
    FEBS letters, 1999, Jul-30, Volume: 456, Issue:1

    Topics: 3T3 Cells; Animals; Apoptosis; Cell Differentiation; Cell Membrane Permeability; Cells, Cultured; Ceramides; Dinucleoside Phosphates; DNA; Humans; Leukemia, Myeloid; Mice; Phorbol Esters; Protein Kinase C; Sphingosine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1999
Ascorbic acid inhibits apoptosis induced by X irradiation in HL60 myeloid leukemia cells.
    Radiation research, 1999, Volume: 152, Issue:5

    Topics: Apoptosis; Ascorbic Acid; fas Receptor; HL-60 Cells; Humans; Leukemia, Myeloid; Peroxides; Proto-Oncogene Proteins c-bcl-2; Tetradecanoylphorbol Acetate; Up-Regulation; X-Rays

1999
GM-CSF rescues TF-1 cells from growth factor withdrawal-induced, but not differentiation-induced apoptosis: the role of BCL-2 and MCL-1.
    Cytokine, 1999, Volume: 11, Issue:11

    Topics: Apoptosis; Cell Differentiation; Cell Survival; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Substances; Humans; Leukemia, Myeloid; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; Proto-Oncogene Proteins c-bcl-2; Tetradecanoylphorbol Acetate; Time Factors; Transfection; Tumor Cells, Cultured

1999
Myeloid leukemia cell growth and differentiation are independent of mitogen-activated protein kinase ERK1/2 activation.
    The Journal of biological chemistry, 2000, Mar-10, Volume: 275, Issue:10

    Topics: Cell Differentiation; Cell Division; Enzyme Activation; Flavonoids; Humans; Leukemia, Myeloid; Lysophospholipids; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Platelet-Derived Growth Factor; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

2000
Prolonged activation of the mitogen-activated protein kinase pathway is required for macrophage-like differentiation of a human myeloid leukemic cell line.
    Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 2000, Volume: 11, Issue:4

    Topics: Blotting, Western; Cell Differentiation; Cell Nucleus; DNA-Binding Proteins; DNA, Antisense; DNA, Complementary; Dose-Response Relationship, Drug; Enzyme Activation; ets-Domain Protein Elk-1; Gene Expression Regulation, Enzymologic; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Immunohistochemistry; Leukemia, Myeloid; Macrophages; MAP Kinase Kinase 1; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Tetradecanoylphorbol Acetate; Time Factors; Transcription Factors; Transfection; Tumor Cells, Cultured

2000
Induction of TrkA expression by differentiation inducers in human myeloid leukemia KG-1 cells.
    Leukemia & lymphoma, 2000, Volume: 36, Issue:5-6

    Topics: Butyrates; Calcitriol; Cell Differentiation; Cytarabine; Drug Synergism; Gene Expression Regulation, Neoplastic; Humans; Leukemia, Myeloid; Receptor, trkA; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

2000
Requirement for caspase activation in monocytic differentiation of myeloid leukemia cells.
    Oncogene, 2000, Aug-10, Volume: 19, Issue:34

    Topics: Amino Acid Chloromethyl Ketones; Caspase 1; Caspase 3; Caspase Inhibitors; Caspases; Cell Differentiation; Cysteine Proteinase Inhibitors; Cytochrome c Group; Enzyme Activation; Humans; Isoenzymes; Leukemia, Myeloid; Mitochondria; Protein Kinase C; Protein Kinase C beta; Serpins; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Viral Proteins

2000
Identification of novel genes differentially expressed in PMA-induced HL-60 cells using cDNA microarrays.
    Molecules and cells, 2000, Dec-31, Volume: 10, Issue:6

    Topics: Base Sequence; Carcinogens; Cell Differentiation; Gene Expression Profiling; Hematopoietic Stem Cells; HL-60 Cells; Humans; Leukemia, Myeloid; Molecular Sequence Data; Nucleic Acid Hybridization; Oligonucleotide Array Sequence Analysis; Proteome; Tetradecanoylphorbol Acetate

2000
Novel vitamin D(3) analog, 21-(3-methyl-3-hydroxy-butyl)-19-nor D(3), that modulates cell growth, differentiation, apoptosis, cell cycle, and induction of PTEN in leukemic cells.
    Blood, 2001, Apr-15, Volume: 97, Issue:8

    Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Calcitriol; Carcinoma; Cell Cycle; Cell Cycle Proteins; Cell Differentiation; Cell Division; Cyclin-Dependent Kinase Inhibitor p27; Dose-Response Relationship, Drug; Female; Gene Expression Regulation, Leukemic; Gene Expression Regulation, Neoplastic; HL-60 Cells; Humans; Leukemia, Myeloid; Male; Microtubule-Associated Proteins; Neoplasm Proteins; Phosphoric Monoester Hydrolases; Prostatic Neoplasms; PTEN Phosphohydrolase; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured; Tumor Suppressor Proteins

2001
Mitochondrial targeting of JNK/SAPK in the phorbol ester response of myeloid leukemia cells.
    Cell death and differentiation, 2001, Volume: 8, Issue:8

    Topics: Apoptosis; bcl-X Protein; Carcinogens; Cell Compartmentation; Cell Differentiation; Cytochrome c Group; Fluorescent Antibody Technique; Gene Expression Regulation, Leukemic; Humans; Immunoblotting; Isoenzymes; Leukemia, Myeloid; Mitochondria; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinases; Monocytes; Myeloid Progenitor Cells; Protein Kinase C; Protein Kinase C beta; Proto-Oncogene Proteins c-bcl-2; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

2001
Evidence for the involvement of the NADPH oxidase enzyme complex in the optimal accumulation of Platelet-activating factor in the human cell line PLB-985.
    Prostaglandins & other lipid mediators, 2001, Volume: 66, Issue:4

    Topics: Calcimycin; Calcium; Cell Line; Gas Chromatography-Mass Spectrometry; Glycerylphosphorylcholine; Humans; Ionophores; Leukemia, Myeloid; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Phosphatidylcholines; Platelet Activating Factor; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; Superoxides; Tetradecanoylphorbol Acetate

2001
Expansion of cytotoxic effectors with lytic activity against autologous blasts from acute myeloid leukaemia patients in complete haematological remission.
    British journal of haematology, 2002, Volume: 116, Issue:2

    Topics: Acute Disease; Adult; Aged; Cell Division; Coculture Techniques; Cytokines; Cytotoxicity Tests, Immunologic; Female; Humans; Immunotherapy; Interferon-gamma; Ionomycin; Ionophores; Killer Cells, Natural; Leukemia, Myeloid; Male; Middle Aged; Signal Transduction; T-Lymphocytes, Cytotoxic; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

2002
Importance of MEK-1/-2 signaling in monocytic and granulocytic differentiation of myeloid cell lines.
    Leukemia, 2002, Volume: 16, Issue:4

    Topics: Antigens, CD; Antineoplastic Agents; Apoptosis; Butadienes; Cell Differentiation; Cell Survival; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Enzyme Inhibitors; Granulocytes; Humans; Leukemia, Myeloid; MAP Kinase Kinase 1; MAP Kinase Kinase 2; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Monocytes; Nitriles; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Signal Transduction; Tetradecanoylphorbol Acetate; Tretinoin

2002
Synergistic induction of apoptosis in human myeloid leukemia cells by phorbol 12-myristate 13-acetate and flavopiridol proceeds via activation of both the intrinsic and tumor necrosis factor-mediated extrinsic cell death pathways.
    Molecular pharmacology, 2002, Volume: 61, Issue:6

    Topics: Antineoplastic Agents; Apoptosis; Arabidopsis Proteins; Carcinogens; Caspase 8; Caspase 9; Caspases; Drug Synergism; Enzyme Precursors; Fatty Acid Desaturases; Flavonoids; Humans; Leukemia, Myeloid; Mitochondria; Piperidines; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; U937 Cells

2002
The histone deacetylase inhibitor sodium butyrate interacts synergistically with phorbol myristate acetate (PMA) to induce mitochondrial damage and apoptosis in human myeloid leukemia cells through a tumor necrosis factor-alpha-mediated process.
    Experimental cell research, 2002, Jul-01, Volume: 277, Issue:1

    Topics: Apoptosis; Butyric Acid; Drug Synergism; Enzyme Activation; Histone Deacetylase Inhibitors; HL-60 Cells; Humans; Leukemia, Myeloid; Mitochondria; Receptors, Tumor Necrosis Factor; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; U937 Cells

2002
Inhibition of functional and morphological differentiation of cultured mouse myeloid leukemia cells by tumor promoters.
    Gan, 1979, Volume: 70, Issue:1

    Topics: Animals; Cell Differentiation; Cells, Cultured; Leukemia, Experimental; Leukemia, Myeloid; Mice; Phagocytosis; Phorbols; Tetradecanoylphorbol Acetate

1979
Human promyelocytic leukemia cells in culture differentiate into macrophage-like cells when treated with a phorbol diester.
    Proceedings of the National Academy of Sciences of the United States of America, 1979, Volume: 76, Issue:6

    Topics: Cell Adhesion; Cell Differentiation; Cell Line; DNA; Humans; Leukemia, Myeloid; Macrophages; Phagocytosis; Phorbols; Protein Biosynthesis; Tetradecanoylphorbol Acetate

1979
Enhancing effect of phorbol esters on induction of differentiation of mouse myeloid leukemia cells by human urinary protein and lipopolysaccharide.
    Cancer research, 1979, Volume: 39, Issue:11

    Topics: Animals; Cell Differentiation; Cells, Cultured; Diterpenes; Drug Synergism; Humans; Leukemia, Experimental; Leukemia, Myeloid; Lipopolysaccharides; Mice; Phagocytosis; Phorbol Esters; Phorbols; Proteins; Tetradecanoylphorbol Acetate

1979
Regulation of acid phosphatase activity in human promyelocytic leukemic cells induced to differentiate in culture.
    The Journal of cell biology, 1979, Volume: 83, Issue:2 Pt 1

    Topics: Acid Phosphatase; Cell Differentiation; Cell Line; Dimethyl Sulfoxide; Endoplasmic Reticulum; Granulocytes; Humans; Isoenzymes; Leukemia, Myeloid; Macrophages; Tetradecanoylphorbol Acetate

1979
Regulation of normal differentiation in mouse and human myeloid leukemic cells by phorbol esters and the mechanism of tumor promotion.
    Proceedings of the National Academy of Sciences of the United States of America, 1979, Volume: 76, Issue:10

    Topics: Animals; Cell Differentiation; Cell Division; Cell Line; Humans; Kinetics; Leukemia, Experimental; Leukemia, Myeloid; Mice; Phagocytosis; Phorbols; Rosette Formation; Tetradecanoylphorbol Acetate

1979
[Differentiation of human normal and leukemic bone marrow and blood cells in tissue culture upon exposure to a tumor promotor].
    Doklady Akademii nauk SSSR, 1979, Volume: 249, Issue:3

    Topics: Bone Marrow; Cell Differentiation; Cells, Cultured; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid; Leukocytes; Lymphocytes; Phorbols; Tetradecanoylphorbol Acetate

1979
Macrophage-like cell transformation and CFU(c) fluctuations in normal and leukemic human marrow cultures treated by phorbol diester.
    Biomedicine / [publiee pour l'A.A.I.C.I.G.], 1979, Volume: 31, Issue:9-10

    Topics: Bone Marrow; Cell Adhesion; Cells, Cultured; Colony-Forming Units Assay; Dose-Response Relationship, Drug; Humans; Leukemia, Myeloid; Macrophages; Phorbols; Tetradecanoylphorbol Acetate

1979
Differentiation and dedifferentiation of the human monocytic leukemia cell line, U937.
    Cell structure and function, 1992, Volume: 17, Issue:5

    Topics: Autoradiography; Cell Differentiation; DNA, Neoplasm; Humans; Leukemia, Myeloid; Macrophages; Phagocytosis; Radioligand Assay; Receptors, Fc; Staining and Labeling; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1992
High production of catalase in hydrogen peroxide-resistant human leukemia HL-60 cell lines.
    Leukemia research, 1992, Volume: 16, Issue:2

    Topics: Catalase; Cell Differentiation; Drug Resistance; Glutathione Peroxidase; Humans; Hydrogen Peroxide; In Vitro Techniques; Leukemia, Myeloid; Peroxidase; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1992
Identification of NF-jun, a novel inducible transcription factor that regulates c-jun gene transcription.
    The EMBO journal, 1992, Volume: 11, Issue:4

    Topics: Base Sequence; Binding Sites; Cell Line; Cycloheximide; Genes, jun; Hodgkin Disease; Humans; Leukemia, Myeloid; Molecular Sequence Data; Molecular Weight; NF-kappa B; Nuclear Proteins; Oligodeoxyribonucleotides; Promoter Regions, Genetic; Proto-Oncogene Proteins c-jun; Tetradecanoylphorbol Acetate; Transcription Factors; Transcription, Genetic; Tumor Necrosis Factor-alpha

1992
Proliferation-linked regulation of type II IMP dehydrogenase gene in human normal lymphocytes and HL-60 leukemic cells.
    Cancer research, 1992, Jan-15, Volume: 52, Issue:2

    Topics: Blotting, Northern; Cell Division; Dimethyl Sulfoxide; Gene Expression; Guanosine; Humans; IMP Dehydrogenase; Leukemia, Myeloid; Lymphocyte Activation; Lymphocytes; Ribavirin; RNA, Messenger; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured

1992
Histamine increases cytosolic Ca2+ in dibutyryl-cAMP-differentiated HL-60 cells via H1 receptors and is an incomplete secretagogue.
    Molecular pharmacology, 1992, Volume: 42, Issue:2

    Topics: Betahistine; Bucladesine; Calcium; Cations; Cell Differentiation; Cytosol; Glucuronidase; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Humans; Ion Channels; Leukemia, Experimental; Leukemia, Myeloid; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Phosphorylation; Receptors, Histamine H1; Secretory Rate; Stimulation, Chemical; Superoxides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine; Virulence Factors, Bordetella

1992
Modulation of protein kinase C-epsilon by phorbol esters in the monoblastoid U937 cell.
    Cancer research, 1992, Oct-15, Volume: 52, Issue:20

    Topics: Cell Differentiation; Enzyme Activation; Enzyme Induction; Humans; Leukemia, Myeloid; Leukemia, Promyelocytic, Acute; Monocytes; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1992
HL-60 cells isolated for resistance to vincristine are defective in 12-O-tetradecanoylphorbol-13-acetate induced differentiation and the formation of a functional AP-1 complex.
    Oncology research, 1992, Volume: 4, Issue:7

    Topics: Cell Adhesion; Cell Differentiation; Drug Resistance; Gene Expression; Genes, fos; Genes, myc; Humans; Leukemia, Myeloid; Proto-Oncogene Proteins c-jun; Proto-Oncogenes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vimentin; Vincristine

1992
Differential expression of the histone H1 zero gene in U937 and HL-60 leukemia cell lines.
    Journal of cellular biochemistry, 1992, Volume: 50, Issue:3

    Topics: Butyrates; Cell Cycle; Cell Differentiation; Dimethyl Sulfoxide; Gene Expression; Genes; HeLa Cells; Histones; Humans; Leukemia, Myeloid; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1992
Phospholipase C-induced monocytic differentiation in a human monocytic leukemia cell line THP-1.
    Leukemia & lymphoma, 1992, Volume: 7, Issue:4

    Topics: Cell Differentiation; Gene Expression; Humans; Leukemia, Myeloid; Monocytes; Proto-Oncogene Mas; Proto-Oncogenes; Receptor, Macrophage Colony-Stimulating Factor; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Type C Phospholipases

1992
Transforming growth factor-beta inhibits phosphorylation of the retinoblastoma susceptibility gene product in human monocytic leukemia cell line JOSK-I.
    The Journal of biological chemistry, 1992, Aug-25, Volume: 267, Issue:24

    Topics: Aphidicolin; Blotting, Northern; Cell Cycle; Cell Division; Cell Line; DNA Replication; Genes, Retinoblastoma; HLA-DR Antigens; Humans; Kinetics; Leukemia, Myeloid; Phosphorylation; Receptors, Transferrin; Retinoblastoma Protein; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Thymidine Kinase; Transforming Growth Factor beta

1992
Differentiation and retrodifferentiation of human myeloid leukemia cells is associated with reversible induction of cell cycle-regulatory genes.
    Cancer research, 1992, Mar-15, Volume: 52, Issue:6

    Topics: Cell Cycle; Cell Differentiation; Cyclins; Down-Regulation; G1 Phase; G2 Phase; Gene Expression Regulation, Leukemic; Genes, Regulator; Humans; Leukemia, Myeloid; RNA, Messenger; Tetradecanoylphorbol Acetate

1992
Detection and characterization of membrane protein changes in multidrug resistant HL-60 cells.
    Oncology research, 1992, Volume: 4, Issue:1

    Topics: Blotting, Western; Cell Differentiation; Dimethyl Sulfoxide; Doxorubicin; Drug Resistance; Humans; In Vitro Techniques; Leukemia, Myeloid; Membrane Glycoproteins; Molecular Weight; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tunicamycin

1992
Temporal relationships between induced changes in c-myc mRNA abundance, proliferation, and differentiation in HL60 cells.
    Differentiation; research in biological diversity, 1992, Volume: 49, Issue:2

    Topics: Cell Differentiation; Cell Division; Cell Transformation, Neoplastic; Dimethyl Sulfoxide; Down-Regulation; Granulocytes; Humans; Leukemia, Experimental; Leukemia, Myeloid; Proto-Oncogene Proteins c-myc; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1992
Stimulatory effect of interleukin-1 beta on the interferon-gamma-dependent HLA-DR production.
    Immunology, 1992, Volume: 76, Issue:1

    Topics: Culture Media; Cytokines; HLA-B7 Antigen; HLA-DR Antigens; Humans; Immunoblotting; Interferon-gamma; Interleukin-1; Leukemia, Myeloid; Recombinant Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1992
Retinoic acid enhances IL-1 beta expression in myeloid leukemia cells and in human monocytes.
    Journal of immunology (Baltimore, Md. : 1950), 1991, Jul-01, Volume: 147, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Blotting, Northern; Bucladesine; Gene Expression; Humans; Interleukin-1; Isoquinolines; Leukemia, Myeloid; Lipopolysaccharides; Monocytes; Piperazines; Protein Kinase Inhibitors; RNA, Messenger; Sulfonamides; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tretinoin; Tumor Cells, Cultured

1991
Na+/H+ antiporter gene expression during monocytic differentiation of HL60 cells.
    The Journal of biological chemistry, 1991, Jul-25, Volume: 266, Issue:21

    Topics: Carrier Proteins; Cell Differentiation; Cycloheximide; Diglycerides; Gene Expression; Humans; In Vitro Techniques; Leukemia, Myeloid; Monocytes; RNA, Messenger; Sodium-Hydrogen Exchangers; Sphingosine; Tetradecanoylphorbol Acetate; Time Factors; Transcription, Genetic; Tumor Cells, Cultured

1991
Rescue from programmed cell death in leukemic and normal myeloid cells.
    Blood, 1991, Aug-15, Volume: 78, Issue:4

    Topics: Amiloride; Animals; Bone Marrow Cells; Carrier Proteins; Cell Differentiation; Cell Survival; DNA; Granulocyte-Macrophage Colony-Stimulating Factor; Granulocytes; Interleukin-3; Leukemia, Myeloid; Mice; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1991
Membrane potential in human myeloid leukemia cell line ML-1: responsiveness of granulocytic and monocytic differentiated cells.
    General physiology and biophysics, 1991, Volume: 10, Issue:1

    Topics: Benzothiazoles; Carbocyanines; Cell Differentiation; Fluorescence; Granulocytes; Humans; Kinetics; Leukemia, Myeloid; Membrane Potentials; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Ouabain; Sodium-Potassium-Exchanging ATPase; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Valinomycin

1991
Preferential localisation of elastase in cytosol of human myeloid leukemia HL-60 cells.
    Biological chemistry Hoppe-Seyler, 1991, Volume: 372, Issue:10

    Topics: Cell Differentiation; Cell Fractionation; Centrifugation, Density Gradient; Chromatography, Gel; Cytosol; Humans; Leukemia, Myeloid; Leukocytes; Pancreatic Elastase; Peroxidase; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured

1991
Protein kinase C-mediated regulation of the expression of CD14 and CD11/CD18 in U937 cells.
    International journal of cancer, 1990, Feb-15, Volume: 45, Issue:2

    Topics: Antigens, CD; Antigens, Differentiation; Antigens, Differentiation, Myelomonocytic; Calcimycin; Calcium; Calmodulin; CD11 Antigens; CD18 Antigens; Cell Differentiation; Humans; Leukemia, Myeloid; Lipopolysaccharide Receptors; Protein Kinase C; Receptors, Leukocyte-Adhesion; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1990
Phorbol ester-treated human acute myeloid leukemia cells secrete G-CSF, GM-CSF and erythroid differentiation factor into serum-free media in primary culture.
    Biochimica et biophysica acta, 1990, Dec-10, Volume: 1055, Issue:3

    Topics: Activins; Acute Disease; Bone Marrow; Culture Media; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Substances; Humans; Inhibins; Leukemia, Myeloid; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1990
Tumor necrosis factor downregulates granulocyte-colony-stimulating factor receptor expression on human acute myeloid leukemia cells and granulocytes.
    The Journal of clinical investigation, 1991, Volume: 87, Issue:3

    Topics: Acute Disease; Alkaloids; Down-Regulation; Granulocyte Colony-Stimulating Factor; Granulocytes; Humans; In Vitro Techniques; Leukemia, Myeloid; Protease Inhibitors; Receptors, Granulocyte Colony-Stimulating Factor; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors; Tumor Necrosis Factor-alpha

1991
A comparison of the HL-60 cell line and human granulocytes to effect the bioactivation of arylamines and related xenobiotics. The binding of 2-aminofluorene to nucleic acids as the result of the respiratory burst.
    Chemico-biological interactions, 1991, Volume: 78, Issue:1

    Topics: Amines; Carcinogens; Cell Differentiation; Chromatography, High Pressure Liquid; Dimethyl Sulfoxide; DNA; Fluorenes; Granulocytes; Humans; Leukemia, Experimental; Leukemia, Myeloid; Neutrophils; Oxygen; Oxygen Consumption; Protein Binding; RNA; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Xenobiotics

1991
Membrane glycoprotein changes associated with anthracycline resistance in HL-60 cells.
    Cancer chemotherapy and pharmacology, 1991, Volume: 28, Issue:2

    Topics: Antibiotics, Antineoplastic; Autoradiography; Cell Line; Culture Techniques; Drug Resistance; Electrophoresis, Polyacrylamide Gel; Epitopes; Glycosylation; Humans; Leukemia, Myeloid; Membrane Glycoproteins; Phenotype; Tetradecanoylphorbol Acetate; Tretinoin; Tunicamycin

1991
Regulation of expression of the leukocyte integrin CD11a (LFA-1) molecule during differentiation of HL-60 cells along the monocyte/macrophage pathway.
    Journal of immunology (Baltimore, Md. : 1950), 1992, Feb-01, Volume: 148, Issue:3

    Topics: Blotting, Northern; Cell Differentiation; Cell Membrane; Gene Expression; Humans; In Vitro Techniques; Leukemia, Myeloid; Lymphocyte Function-Associated Antigen-1; Macrophages; Monocytes; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured

1992
Inhibition of protein kinase C is associated with a decrease in c-myc expression in human myeloid leukemia cells.
    FEBS letters, 1991, Dec-02, Volume: 294, Issue:1-2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Blotting, Northern; Cell Line; Enzyme Activation; Gene Expression; Gene Expression Regulation, Neoplastic; Genes, myc; Humans; Isoquinolines; Kinetics; Leukemia, Myeloid; Piperazines; Protein Kinase C; Pyrimidine Nucleosides; RNA, Messenger; RNA, Neoplasm; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate

1991
Phorbol myristate acetate inhibits phosphoinositol lipid-specific phospholipase C activity via protein kinase C activation in conditions inducing differentiation in HL-60 cells.
    Cell biochemistry and function, 1991, Volume: 9, Issue:4

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Cell Differentiation; Cell Membrane; Clone Cells; Enzyme Activation; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Inositol Phosphates; Isoquinolines; Leukemia, Myeloid; Lipid Metabolism; Piperazines; Protein Kinase C; Staurosporine; Streptolysins; Subcellular Fractions; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Type C Phospholipases

1991
An autocrine role for urokinase in phorbol ester-mediated differentiation of myeloid cell lines.
    The Journal of clinical investigation, 1991, Volume: 87, Issue:3

    Topics: Cell Adhesion; Cell Differentiation; Cysteine Endopeptidases; Hematopoiesis; Humans; Immunologic Techniques; In Vitro Techniques; Leukemia, Myeloid; Macrophages; Peptide Fragments; Pulmonary Alveoli; Receptors, Cell Surface; Receptors, Urokinase Plasminogen Activator; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Urokinase-Type Plasminogen Activator

1991
Increase in the expression of a family of small guanosine triphosphate-binding proteins, rab proteins, during induced phagocyte differentiation.
    The Journal of clinical investigation, 1991, Volume: 87, Issue:3

    Topics: Animals; Blotting, Northern; Blotting, Western; Cell Compartmentation; Cell Differentiation; Cell Membrane; Cytoplasmic Granules; Cytosol; Dimethyl Sulfoxide; Gene Expression; GTP-Binding Proteins; Guinea Pigs; Humans; In Vitro Techniques; Leukemia, Myeloid; Neutrophils; Phagocytes; Pulmonary Alveoli; RNA, Messenger; Superoxides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1991
Down regulation of myeloperoxidase gene associated with specific nuclease hypersensitive sites during TPA induced differentiation of HL-60.
    Leukemia, 1991, Volume: 5, Issue:3

    Topics: Blotting, Southern; Cell Differentiation; Deoxyribonuclease I; Down-Regulation; Humans; Introns; Leukemia, Experimental; Leukemia, Myeloid; Peroxidase; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1991
Expression of the early growth response 1 and 2 zinc finger genes during induction of monocytic differentiation.
    The Journal of clinical investigation, 1991, Volume: 88, Issue:2

    Topics: Cell Differentiation; Dexamethasone; Dimethyl Sulfoxide; Gene Expression; Humans; Leukemia, Myeloid; Macrophage Colony-Stimulating Factor; Monocytes; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Zinc Fingers

1991
Levels of p53 protein increase with maturation in human hematopoietic cells.
    Cancer research, 1991, Aug-15, Volume: 51, Issue:16

    Topics: Acute Disease; Adult; Amino Acid Sequence; Bone Marrow; Bone Marrow Cells; Cell Division; Cell Line; Cells, Cultured; Flow Cytometry; Gene Expression; Hematopoietic Stem Cells; Humans; Immunoblotting; Kinetics; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid; Molecular Sequence Data; Oligopeptides; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53

1991
The effects of lithium on the growth and phorbol ester (TPA) induced differentiation of two HL-60 sublines.
    Leukemia research, 1991, Volume: 15, Issue:8

    Topics: Cell Differentiation; Cell Division; DNA, Neoplasm; Humans; Leukemia, Experimental; Leukemia, Myeloid; Lithium; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1991
Characterization of phospholipase A2 in monocytic cell lines. Functional and biochemical aspects of membrane association.
    The Biochemical journal, 1991, Jun-15, Volume: 276 ( Pt 3)

    Topics: Arachidonic Acid; Arachidonic Acids; Calcium; Cell Line; Cell Membrane; Cell Transformation, Neoplastic; Cytosol; Edetic Acid; Enzyme Activation; Humans; Leukemia, Myeloid; Magnesium; Membrane Proteins; Phospholipases A; Phospholipases A2; Substrate Specificity; Tetradecanoylphorbol Acetate

1991
Regulation of cellular trans-activating activities in two different promonocytic leukemia cell lines.
    Cancer letters, 1991, Volume: 60, Issue:1

    Topics: Antigens, Differentiation; Base Sequence; DNA Mutational Analysis; DNA, Neoplasm; Gene Expression Regulation, Leukemic; HIV Long Terminal Repeat; Humans; Leukemia, Myeloid; Molecular Sequence Data; Plasmids; Tetradecanoylphorbol Acetate; Transcriptional Activation; Transfection; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

1991
Inhibition of phorbol ester-induced monocytic differentiation by dexamethasone is associated with down-regulation of c-fos and c-jun (AP-1).
    Journal of cellular physiology, 1991, Volume: 149, Issue:1

    Topics: Actins; Cell Differentiation; Dexamethasone; Down-Regulation; Gene Expression Regulation; Genes, fos; Genes, jun; Humans; Leukemia, Myeloid; Monocytes; Promoter Regions, Genetic; Protein Kinase C; Proto-Oncogene Proteins c-jun; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured

1991
Relationship of acivicin-induced monocytoid differentiation of human myeloid leukemia cells to acivicin-induced modulation of growth factor, cytokine, and protooncogene mRNA expression.
    Cancer research, 1991, Feb-15, Volume: 51, Issue:4

    Topics: Antibiotics, Antineoplastic; Cell Differentiation; Cell Transformation, Neoplastic; Cytokines; Gene Expression Regulation, Neoplastic; Genes, myc; Granulocyte-Macrophage Colony-Stimulating Factor; Heat-Shock Proteins; Humans; Interleukin-1; Interleukin-3; Interleukin-6; Isoxazoles; Leukemia, Myeloid; Monocytes; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myb; Proto-Oncogenes; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Necrosis Factor-alpha

1991
Expression of the jun-B gene during induction of monocytic differentiation.
    Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1991, Volume: 2, Issue:1

    Topics: Bryostatins; Calcitriol; Cell Differentiation; DNA-Binding Proteins; Gene Expression; Humans; Lactones; Leukemia, Myeloid; Macrolides; Monocytes; Proto-Oncogene Proteins c-jun; Proto-Oncogenes; Tetradecanoylphorbol Acetate; Transcription, Genetic

1991
Differential effects of c-myb and c-fes antisense oligodeoxynucleotides on granulocytic differentiation of human myeloid leukemia HL60 cells.
    Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1990, Volume: 1, Issue:11

    Topics: Cell Cycle; Cell Differentiation; Granulocytes; Leukemia, Myeloid; Oligonucleotides, Antisense; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fes; Proto-Oncogene Proteins c-myb; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured; Vitamin D

1990
Inhibition of TPA-induced monocytic differentiation in THP-1 human monocytic leukemic cells by staurosporine, a potent protein kinase C inhibitor.
    Leukemia research, 1990, Volume: 14, Issue:5

    Topics: Alkaloids; Cell Differentiation; Cell Division; Gene Expression; Humans; Leukemia, Myeloid; Macrophages; Monocytes; Protein Kinase C; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogenes; Receptor, Macrophage Colony-Stimulating Factor; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured

1990
Differentiating agents facilitate infection of myeloid leukemia cell lines by monocytotropic HIV-1 strains.
    Blood, 1990, Nov-15, Volume: 76, Issue:10

    Topics: Bucladesine; Calcitriol; CD4 Antigens; Cell Differentiation; Cell Line; Dimethyl Sulfoxide; DNA, Viral; Gene Expression; HIV Infections; HIV-1; Humans; Leukemia, Myeloid; Tetradecanoylphorbol Acetate; Thymidine; Tretinoin; Tritium; Virus Replication

1990
Control of interleukin-1 beta expression by protein kinase C and cyclic adenosine monophosphate in myeloid leukemia cells.
    Blood, 1990, Dec-01, Volume: 76, Issue:11

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Bucladesine; Colforsin; Cyclic AMP; Dinoprostone; Enzyme Activation; Gene Expression; Humans; Interleukin-1; Isoquinolines; Leukemia, Myeloid; Leukemia, Promyelocytic, Acute; Piperazines; Protein Kinase C; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1990
Increased expression and DNA-binding activity of transcription factor Sp1 in doxorubicin-resistant HL-60 leukemia cells.
    Molecular and cellular biology, 1990, Volume: 10, Issue:10

    Topics: Base Sequence; Binding Sites; Blotting, Western; DNA-Binding Proteins; Doxorubicin; Drug Resistance; Humans; Leukemia, Myeloid; Molecular Sequence Data; Oligonucleotide Probes; Sp1 Transcription Factor; Tetradecanoylphorbol Acetate; Transcription Factors; Tumor Cells, Cultured

1990
Cross-resistance to tumour promoters in human cancer cell lines resistant to adriamycin or cisplatin.
    British journal of cancer, 1990, Volume: 62, Issue:3

    Topics: Cell Division; Cell Line; Chemical Phenomena; Chemistry; Cisplatin; Cross Reactions; Doxorubicin; Drug Resistance; Ethers, Cyclic; Humans; Leukemia, Myeloid; Lung Neoplasms; Lyngbya Toxins; Okadaic Acid; Tetradecanoylphorbol Acetate

1990
A far upstream element stimulates c-myc expression in undifferentiated leukemia cells.
    The Journal of biological chemistry, 1990, Oct-25, Volume: 265, Issue:30

    Topics: Base Sequence; Cell Differentiation; Dimethyl Sulfoxide; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; Humans; In Vitro Techniques; Leukemia, Myeloid; Molecular Sequence Data; Oligonucleotides; Proto-Oncogene Proteins c-myc; Proto-Oncogenes; Regulatory Sequences, Nucleic Acid; Restriction Mapping; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1990
Phorbol ester-induced macrophage-like differentiation of human promyelocytic leukemia (HL-60) cells occurs independently of transferrin availability.
    Cancer research, 1990, Nov-15, Volume: 50, Issue:22

    Topics: Cell Differentiation; Cell Division; Down-Regulation; Ferric Compounds; Humans; In Vitro Techniques; Leukemia, Myeloid; Macrophages; Receptors, Transferrin; Tetradecanoylphorbol Acetate; Transferrin; Tumor Cells, Cultured

1990
Myeloid leukemia differentiation by phorbol ester and retinoic acid: a practical approach.
    Journal of clinical laboratory analysis, 1990, Volume: 4, Issue:5

    Topics: Cell Transformation, Neoplastic; Diagnosis, Differential; Humans; Leukemia, Erythroblastic, Acute; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid; Leukemia, Promyelocytic, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tetradecanoylphorbol Acetate; Tretinoin

1990
cis-diamminedichloroplatinum(II) cross-linking of the human myeloid cell nuclear differentiation antigen to DNA in HL-60 cells following 1,25-dihydroxy vitamin D3-induced monocyte differentiation.
    Cancer research, 1990, Feb-15, Volume: 50, Issue:4

    Topics: Antigens, Differentiation, Myelomonocytic; Calcitriol; Cell Differentiation; Cell Line; Cisplatin; DNA, Neoplasm; Humans; Immunoblotting; Leukemia, Myeloid; Monocytes; Tetradecanoylphorbol Acetate

1990
The THP-1 cell line is a urokinase-secreting mononuclear phagocyte with a novel defect in the production of plasminogen activator inhibitor-2.
    Journal of immunology (Baltimore, Md. : 1950), 1990, Mar-01, Volume: 144, Issue:5

    Topics: Blotting, Northern; Cross Reactions; Gene Expression; Humans; Leukemia, Myeloid; Lipopolysaccharides; Monocytes; Plasminogen Inactivators; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Urokinase-Type Plasminogen Activator

1990
Expression of selected genes in differentiated HL-60 cells and primary cells from human leukemias.
    Cancer biochemistry biophysics, 1990, Volume: 11, Issue:1

    Topics: Base Sequence; Cell Differentiation; Cloning, Molecular; Dimethyl Sulfoxide; DNA, Neoplasm; Gene Expression; Genomic Library; Granulocytes; Humans; Leukemia, Experimental; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid; Molecular Sequence Data; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1990
Expression of the macrophage specific colony-stimulating factor (CSF-1) during human monocytic differentiation.
    Biochemical and biophysical research communications, 1986, Dec-30, Volume: 141, Issue:3

    Topics: Cell Differentiation; Cell Line; Colony-Stimulating Factors; Gene Expression Regulation; Humans; Leukemia, Myeloid; Macrophages; Monocytes; Oncogenes; Proto-Oncogene Mas; RNA; Tetradecanoylphorbol Acetate; Transcription, Genetic

1986
Elevation of a potassium current in differentiating human leukemic (HL-60) cells.
    Journal of cellular physiology, 1987, Volume: 132, Issue:2

    Topics: Calcium; Cell Differentiation; Cell Line; Cesium; Chlorides; Electric Conductivity; Humans; Ion Channels; Leukemia, Myeloid; Macrophages; Potassium; Tetradecanoylphorbol Acetate; Tretinoin

1987
Epstein-Barr virus episome-based promoter function in human myeloid cells.
    Nucleic acids research, 1989, Mar-11, Volume: 17, Issue:5

    Topics: Cell Differentiation; Cell Line; Cell-Free System; Chloramphenicol O-Acetyltransferase; Endoplasmic Reticulum Chaperone BiP; Genes, Viral; Herpesvirus 4, Human; Humans; Leukemia, Myeloid; Promoter Regions, Genetic; Replicon; Tetradecanoylphorbol Acetate; Transfection

1989
Autocrine regulation of 1,25-dihydroxycholecalciferol metabolism in myelomonocytic cells.
    Immunology, 1989, Volume: 68, Issue:2

    Topics: Calcitriol; Cell Division; Humans; Leukemia, Myeloid; Mixed Function Oxygenases; Monocytes; Receptors, Calcitriol; Receptors, Steroid; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1989
Synergistic effects of phorbol ester and INF-gamma on the induction of indoleamine 2,3-dioxygenase in THP-1 monocytic leukemia cells.
    Journal of immunology (Baltimore, Md. : 1950), 1989, Nov-01, Volume: 143, Issue:9

    Topics: Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Induction; Humans; In Vitro Techniques; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Leukemia, Myeloid; Monocytes; Protein Kinase C; Tetradecanoylphorbol Acetate; Time Factors; Tryptophan Oxygenase; Tumor Cells, Cultured

1989
Induction of macrophage-like differentiation of HL60 human myeloid leukemia cells by phorbol myristate acetate triggers an early decline in inositol lipid breakdown.
    Experimental hematology, 1989, Volume: 17, Issue:4

    Topics: Cell Differentiation; Cell Division; Cell Line; Diglycerides; DNA; Glycerophosphates; Humans; Inositol; Inositol Phosphates; Leukemia, Myeloid; Macrophages; Tetradecanoylphorbol Acetate; Thymidine

1989
Intranuclear distribution of the human myeloid cell nuclear differentiation antigen in HL-60 cells.
    Journal of cellular physiology, 1989, Volume: 141, Issue:1

    Topics: Cell Differentiation; Chromatin; Deoxyribonuclease I; DNA Damage; DNA-Binding Proteins; Humans; Kinetics; Leukemia, Myeloid; Nuclear Proteins; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1989
Role of biologic response modifiers in the growth and differentiation of myeloid leukemic cells.
    Current topics in microbiology and immunology, 1989, Volume: 149

    Topics: Animals; Calcitriol; Cell Differentiation; Cell Division; Colony-Stimulating Factors; Growth Substances; Humans; Leukemia, Myeloid; Mice; Tetradecanoylphorbol Acetate; Transforming Growth Factors

1989
Regulation of interleukin-1 beta and tumor necrosis factor secretion by the human monocytic leukemia cell line, THP-1.
    Agents and actions, 1989, Volume: 27, Issue:3-4

    Topics: Enzyme-Linked Immunosorbent Assay; Humans; Interleukin-1; Leukemia, Myeloid; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

1989
Involvement of two intracellular messenger systems, protein kinase C and cyclic AMP, in the regulation of c-fos gene expression in human promyelocytic leukemia (HL-60) cells.
    Journal of biochemistry, 1987, Volume: 102, Issue:6

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Cyclic AMP; Diglycerides; Dinoprostone; Gene Expression Regulation; Humans; Kinetics; Leukemia, Myeloid; Phorbol 12,13-Dibutyrate; Phorbol Esters; Prostaglandins E; Protein Kinase C; Proto-Oncogenes; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1987
Induction of adenosine deaminase and 5' nucleotidase activity in cultured human blood monocytes and monocytic leukemia (THP-1) cells by differentiating agents.
    Journal of leukocyte biology, 1988, Volume: 44, Issue:3

    Topics: 5'-Nucleotidase; Adenosine Deaminase; Cell Differentiation; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Induction; Humans; Interferon-gamma; Leukemia, Myeloid; Lipopolysaccharides; Monocytes; Nucleoside Deaminases; Nucleotidases; Recombinant Proteins; Tetradecanoylphorbol Acetate; Vitamin A

1988
Expression of tissue transglutaminase in cultured monocytic leukemia (THP-1) cells during differentiation.
    Cancer research, 1986, Volume: 46, Issue:3

    Topics: Bucladesine; Cell Differentiation; Dimethyl Sulfoxide; Humans; Immunosorbent Techniques; Interferon-gamma; Leukemia, Myeloid; Macrophages; Phagocytosis; Recombinant Proteins; Tetradecanoylphorbol Acetate; Transglutaminases; Tretinoin; Vitamin A

1986
Modulation of transglutaminase activity in mononuclear phagocytes and macrophage-like tumor cell lines by differentiation agents.
    Experimental cell research, 1987, Volume: 168, Issue:1

    Topics: Animals; Bone Marrow Cells; Calcitriol; Cell Differentiation; Cell Line; Dexamethasone; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid; Macrophages; Male; Mice; Mice, Inbred BALB C; Phagocytes; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Transglutaminases; Tretinoin

1987
Transcriptional regulation of the leukocyte adherence protein beta subunit during human myeloid cell differentiation.
    The Journal of biological chemistry, 1988, Sep-25, Volume: 263, Issue:27

    Topics: CD18 Antigens; Cell Adhesion; Cell Differentiation; Cloning, Molecular; Dimethylformamide; DNA; Gene Expression Regulation; Granulocytes; Humans; Leukemia, Myeloid; Macromolecular Substances; Membrane Glycoproteins; Nucleic Acid Hybridization; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tretinoin; Tumor Cells, Cultured

1988
Changes in isoenzyme profiles during induction of differentiation in human myelomonocytic leukemia cell lines.
    Cancer research, 1986, Volume: 46, Issue:12 Pt 1

    Topics: Acid Phosphatase; beta-N-Acetylhexosaminidases; Carboxylic Ester Hydrolases; Cell Adhesion; Cell Differentiation; Cell Division; Cell Line; Humans; Isoenzymes; L-Lactate Dehydrogenase; Leukemia, Myeloid; Tetradecanoylphorbol Acetate

1986
Expression of leukocyte adherence-related glycoproteins during differentiation of HL-60 promyelocytic leukemia cells.
    Journal of immunology (Baltimore, Md. : 1950), 1987, Jan-15, Volume: 138, Issue:2

    Topics: Antigens, Surface; Cell Adhesion; Cell Differentiation; Cell Line; Glycoproteins; Granulocytes; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Macrophages; Monocytes; Neutrophils; Receptors, Complement; Receptors, Complement 3b; Tetradecanoylphorbol Acetate

1987
Loss and reappearance of transferrin receptors in human leukemic cell lines.
    Experimental cell biology, 1986, Volume: 54, Issue:2

    Topics: Butyrates; Butyric Acid; Cell Differentiation; Cell Line; Dimethyl Sulfoxide; DNA Replication; Heme; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Receptors, Cell Surface; Receptors, Transferrin; Tetradecanoylphorbol Acetate; Transferrin; Tretinoin

1986
Phorbol ester-induced regulation of transferrin receptors in human leukemia K562 cells.
    Cell structure and function, 1986, Volume: 11, Issue:2

    Topics: Cell Line; Cell Membrane; Humans; Kinetics; Leukemia, Myeloid; Phorbols; Receptors, Cell Surface; Receptors, Transferrin; Tetradecanoylphorbol Acetate; Transferrin

1986
Control of HL-60 monocytic differentiation. Different pathways and uncoupled expression of differentiation markers.
    Experimental cell research, 1987, Volume: 168, Issue:1

    Topics: Antigens, Surface; Butyrates; Butyric Acid; Cell Differentiation; Cell Division; Cell Line; Esterases; Humans; Interphase; Kinetics; Leukemia, Myeloid; Monocytes; Superoxides; Tetradecanoylphorbol Acetate

1987
Cyclic AMP-like effects of polyamines on phosphatidylcholine synthesis and protein phosphorylation in human promyelocytic leukemia HL60 cells. Comparison with the effects of phorbol ester.
    FEBS letters, 1987, Mar-23, Volume: 213, Issue:2

    Topics: Bucladesine; Cell Line; Cyclic AMP; Drug Synergism; Humans; Leukemia, Myeloid; Phosphatidylcholines; Phosphoproteins; Phosphorylation; Polyamines; Protein Kinase C; Protein Kinases; Putrescine; Spermine; Tetradecanoylphorbol Acetate

1987
Ca2+ and phorbol ester synergistically induce HL-60 differentiation.
    FEBS letters, 1986, Sep-29, Volume: 206, Issue:1

    Topics: Antigens, Surface; Calcimycin; Calcium; Cell Differentiation; Cell Line; Drug Synergism; Granulocytes; Humans; Leukemia, Myeloid; Macrophages; Monocytes; Tetradecanoylphorbol Acetate

1986
sn-1,2-Diacylglycerols and phorbol diesters stimulate thromboxane synthesis by de novo synthesis of prostaglandin H synthase in human promyelocytic leukemia cells.
    The Journal of clinical investigation, 1987, Volume: 79, Issue:3

    Topics: Arachidonic Acid; Arachidonic Acids; Calcimycin; Cell Differentiation; Cell Line; Diglycerides; Glycerides; Humans; Kinetics; Leukemia, Myeloid; Macrophages; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Tetradecanoylphorbol Acetate; Thromboxane B2; Trifluoperazine

1987
A factor inducing differentiation of the human monocytic cell line U-937 produced by 12-O-tetradecanoylphorbol 13-acetate-treated U-937.
    Japanese journal of cancer research : Gann, 1987, Volume: 78, Issue:3

    Topics: Cell Differentiation; Cell Line; Humans; Leukemia, Myeloid; Macrophages; Tetradecanoylphorbol Acetate

1987
Differentiation by a tumor promoter of lymphoblastoid cell lines with and without Ph1 chromosome from a chronic myelogenous leukemia patient.
    Japanese journal of cancer research : Gann, 1987, Volume: 78, Issue:5

    Topics: Animals; Carcinogens; Cell Differentiation; Cell Line; Humans; In Vitro Techniques; Leukemia, Myeloid; Mice; Philadelphia Chromosome; Tetradecanoylphorbol Acetate

1987
Induction of differentiation of mouse myeloid leukemia M1 cells by serum of patients with chronic myeloid leukemia.
    Japanese journal of cancer research : Gann, 1988, Volume: 79, Issue:12

    Topics: Animals; Cell Differentiation; Culture Media; Growth Inhibitors; Humans; Interleukin-6; Leukemia Inhibitory Factor; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid; Leukemia, Myelomonocytic, Chronic; Lymphokines; Macrophages; Mice; Phytohemagglutinins; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1988
Ganglioside GM3 as a modulator of differentiation of mouse myeloid leukemia cells (M1-T22).
    Cell structure and function, 1988, Volume: 13, Issue:2

    Topics: Animals; Cell Differentiation; Dexamethasone; G(M3) Ganglioside; Gangliosides; Globosides; Glycolipids; Humans; Lactosylceramides; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Mice; Phagocytosis; Tetradecanoylphorbol Acetate; Trihexosylceramides; Tumor Cells, Cultured

1988
Changes in phosphoproteins during commitment of HL60 cells to monocyte differentiation: evidence for multiple protein kinase involvement.
    Experimental hematology, 1988, Volume: 16, Issue:7

    Topics: Cell Differentiation; Humans; Leukemia, Myeloid; Male; Middle Aged; Monocytes; Neoplasm Proteins; Phosphoproteins; Phosphorylation; Protein Kinases; Protein Processing, Post-Translational; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1988
Human pro-IL-1 beta gene expression in monocytic cells is regulated by two distinct pathways.
    Journal of immunology (Baltimore, Md. : 1950), 1988, Apr-01, Volume: 140, Issue:7

    Topics: Cell Line; Gene Expression Regulation; Half-Life; Humans; Interleukin-1; Kinetics; Leukemia, Myeloid; Lipopolysaccharides; Monocytes; Protein Precursors; Protein Processing, Post-Translational; RNA Processing, Post-Transcriptional; Tetradecanoylphorbol Acetate

1988
Immunochemical evidence that three protein kinase C isozymes increase in abundance during HL-60 differentiation induced by dimethyl sulfoxide and retinoic acid.
    The Journal of biological chemistry, 1988, Mar-05, Volume: 263, Issue:7

    Topics: Amino Acid Sequence; Animals; Brain; Cattle; Cell Differentiation; Cytosol; Dimethyl Sulfoxide; Electrophoresis, Polyacrylamide Gel; Humans; Isoenzymes; Leukemia, Myeloid; Molecular Sequence Data; Protein Kinase C; Rabbits; Rats; Sequence Homology, Nucleic Acid; Tetradecanoylphorbol Acetate; Tissue Distribution; Tretinoin; Tumor Cells, Cultured

1988
Partial purification and characterization of phorbol ester-regulated translational inhibitor(s) in human HL-60 leukemic cells.
    The Journal of biological chemistry, 1986, Apr-15, Volume: 261, Issue:11

    Topics: Animals; Cell Extracts; Cell Line; Chromatography; Electrophoresis, Polyacrylamide Gel; Eukaryotic Initiation Factor-2; Fructosephosphates; Globins; Humans; Kinetics; Leukemia, Myeloid; Peptide Initiation Factors; Phorbols; Phosphorylation; Protein Biosynthesis; Proteins; Rabbits; Reticulocytes; RNA, Messenger; Tetradecanoylphorbol Acetate

1986
In vitro differentiation and establishment of cell lines derived from human myelomonocytic leukemia cells.
    Immunology letters, 1986, Volume: 12, Issue:4

    Topics: Cell Differentiation; Cell Line; Culture Media; Humans; Leukemia, Myeloid; Macrophages; Tetradecanoylphorbol Acetate

1986
Phorbol ester induces c-sis gene transcription in stem cell line K-562.
    Molecular and cellular biology, 1986, Volume: 6, Issue:5

    Topics: Cell Differentiation; Cell Line; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid; Oncogenes; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic

1986
Leukemic cell maturation: variability of the myeloid leukemic cell phenotype.
    Blood cells, 1986, Volume: 12, Issue:1

    Topics: Butyrates; Butyric Acid; Cell Differentiation; Cell Division; Cell Line; Cytarabine; Dimethyl Sulfoxide; Drug Resistance; Histocytochemistry; Humans; Leukemia, Myeloid; Phenotype; Tetradecanoylphorbol Acetate; Vitamin A

1986
Differentiation-associated carbohydrate chain on human hematopoietic cells recognized by Clerodendron trichotomum lectin.
    Leukemia research, 1987, Volume: 11, Issue:7

    Topics: Carbohydrate Metabolism; Cell Differentiation; Cell Line; Erythrocytes; Hematopoietic Stem Cells; Humans; Lectins; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Neoplastic Stem Cells; Plant Lectins; Receptors, Mitogen; Tetradecanoylphorbol Acetate

1987
The bcr-c-abl tyrosine kinase activity is extinguished by TPA in K562 leukemia cells.
    FEBS letters, 1987, Oct-05, Volume: 222, Issue:2

    Topics: Cell Differentiation; Cell Line; Humans; Immunoelectrophoresis; Kinetics; Leukemia, Myeloid; Oncogenes; Protein-Tyrosine Kinases; Tetradecanoylphorbol Acetate

1987
Phorbol ester-induced loss of cell surface sialic acid enhances target cell sensitivity to cytolysis by natural killer (NK) cells.
    Transactions of the Association of American Physicians, 1987, Volume: 100

    Topics: Cell Line; Cell Membrane; Cytotoxicity, Immunologic; Freeze Fracturing; Humans; Killer Cells, Natural; Leukemia, Myeloid; Melanoma; Microscopy, Electron; Sialic Acids; Tetradecanoylphorbol Acetate

1987
Occurrence of particular isoenzymes in fresh and cultured leukemia-lymphoma cells. I. Tartrate-resistant acid phosphatase isoenzyme.
    Cancer, 1986, May-01, Volume: 57, Issue:9

    Topics: Acid Phosphatase; B-Lymphocytes; Cell Differentiation; Cell Line; Humans; Isoelectric Focusing; Isoenzymes; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Lymphoma; Monocytes; Tartrates; Tetradecanoylphorbol Acetate

1986
Establishment and characterization of four human monocytoid leukemia cell lines (JOSK-I, -S, -M and -K) with capabilities of monocyte-macrophage lineage differentiation and constitutive production of interleukin 1.
    Cancer research, 1986, Volume: 46, Issue:6

    Topics: Aged; Cell Differentiation; Cell Line; Dimethyl Sulfoxide; Female; Humans; Interleukin-1; Karyotyping; Leukemia, Myeloid; Macrophages; Male; Middle Aged; Monocytes; Phagocytosis; Philadelphia Chromosome; Tetradecanoylphorbol Acetate; Tretinoin

1986
1,25-Dihydroxycholecalciferol-induced differentiation of myelomonocytic leukemic cells unresponsive to colony stimulating factors and phorbol esters.
    Journal of cellular physiology, 1986, Volume: 129, Issue:3

    Topics: Animals; Calcitriol; Cell Differentiation; Cell Division; Cell Line; Colony-Stimulating Factors; Granulocytes; Histocytochemistry; Kinetics; Leukemia, Myeloid; Macrophages; Mice; Mice, Inbred BALB C; Tetradecanoylphorbol Acetate

1986
Occurrence of particular isoenzymes in fresh and cultured leukemia-lymphoma cells. III. Esterase isoenzyme in monocytes.
    Cancer, 1987, Jan-01, Volume: 59, Issue:1

    Topics: B-Lymphocytes; Carboxylic Ester Hydrolases; Cell Differentiation; Cell Line; Enzyme Activation; Humans; Isoenzymes; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lymphoma; Monocytes; Naphthol AS D Esterase; Tetradecanoylphorbol Acetate

1987
Uracil-DNA glycosylase in benign and malignant maturing human hematopoietic cells.
    Mutation research, 1986, Volume: 175, Issue:2

    Topics: Cell Survival; DNA Glycosylases; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid; Lymphoma, Large B-Cell, Diffuse; N-Glycosyl Hydrolases; Reticulocytes; Tetradecanoylphorbol Acetate; Uracil-DNA Glycosidase

1986
Increased glucocorticoid receptor concentration in macrophage differentiation of myeloid leukemia cells with 12-O-tetradecanoylphorbol-13-acetate.
    Cancer research, 1985, Volume: 45, Issue:6

    Topics: Cell Count; Cell Differentiation; Cell Line; Cytosol; DNA, Neoplasm; Humans; Leukemia, Myeloid; Macrophages; Phenotype; Phorbols; Receptors, Glucocorticoid; Receptors, Steroid; Tetradecanoylphorbol Acetate

1985
Changes in cell surface glycoproteins and antigens during differentiation of the human myeloid leukemia cell lines ML-1, ML-2, and HL-60.
    Cancer research, 1985, Volume: 45, Issue:6

    Topics: Antigens, Surface; Cell Differentiation; Cell Line; Electrophoresis, Polyacrylamide Gel; Glycoproteins; Humans; Leukemia, Myeloid; Membrane Proteins; Tetradecanoylphorbol Acetate; Tretinoin

1985
Effects of 1-beta-D-arabinofuranosylcytosine and phorbol ester on differentiation of human K562 erythroleukemia cells.
    Molecular pharmacology, 1985, Volume: 27, Issue:6

    Topics: Cell Differentiation; Cell Line; Cytarabine; DNA Replication; Globins; Glycophorins; Heme; Humans; Kinetics; Leukemia, Erythroblastic, Acute; Leukemia, Myeloid; Nucleic Acid Hybridization; Phorbols; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic

1985
Changes in isoenzyme patterns expressed by the erythroleukemia cell lines K-562 and HEL after induction of differentiation.
    Haematology and blood transfusion, 1985, Volume: 29

    Topics: Cell Differentiation; Cell Line; Glycoproteins; Growth Inhibitors; Humans; Interleukin-6; Isoenzymes; Leukemia Inhibitory Factor; Leukemia, Erythroblastic, Acute; Leukemia, Myeloid; Lymphokines; Tetradecanoylphorbol Acetate

1985
Accessory function of human leukemic cell lines: properties of B and B-K562 hybrid cell lines.
    European journal of immunology, 1985, Volume: 15, Issue:3

    Topics: Animals; Antibodies, Monoclonal; B-Lymphocytes; Cell Differentiation; Cell Line; Histocompatibility Antigens Class II; HLA-DR Antigens; Humans; Hybrid Cells; Leukemia, Experimental; Leukemia, Myeloid; Monocytes; Phenotype; Receptors, Antigen, B-Cell; T-Lymphocytes; Tetradecanoylphorbol Acetate

1985
Failure of 1-oleoyl-2-acetylglycerol to mimic the cell-differentiating action of 12-O-tetradecanoylphorbol 13-acetate in HL-60 cells.
    The Journal of biological chemistry, 1985, Nov-15, Volume: 260, Issue:26

    Topics: Acid Phosphatase; Animals; Brain; Calcimycin; Cell Adhesion; Cell Differentiation; Cell Line; Diglycerides; Enzyme Activation; Glycerides; Humans; Leukemia, Myeloid; Mice; Molecular Weight; Phorbols; Phosphoproteins; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate; Type C Phospholipases

1985