tetradecanoylphorbol acetate has been researched along with Insulin Sensitivity in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (9.68) | 18.7374 |
| 1990's | 10 (32.26) | 18.2507 |
| 2000's | 11 (35.48) | 29.6817 |
| 2010's | 6 (19.35) | 24.3611 |
| 2020's | 1 (3.23) | 2.80 |
| Authors | Studies |
|---|---|
| Chew, CH; Choo, QC; Muhammad, TST; Tham, YY | 1 |
| Khoramdin, B; Montessuit, C; Praplan, G; Viglino, C | 1 |
| Dey, CS; Mishra, D | 1 |
| D'Aquino, K; Feener, EP; King, GL; Li, Q; Maeda, Y; Mima, A; Mizutani, K; Park, K; Rask-Madsen, C; White, MF; Winnay, J | 1 |
| Bennett, G; DeFuria, J; Greenberg, AS; Obin, MS; Shaul, ME; Strissel, KJ | 1 |
| Chang, TW; Deng, YT; Lee, MS; Lin, JK | 1 |
| Dong, LQ; Holmes, BM; Hu, D; Langlais, PR; Lee, H; Liu, M; Riojas, RA; Villarreal, R; Wei, L; Yang, X; Zhou, L | 1 |
| Aharoni, D; Buchs, A; Elberg, G; Katz, Y; Levi, O; Mor, A; Ramot, Y; Rapoport, MJ; Weiss, M; Weissgarten, J | 1 |
| Dallas-Yang, Q; Jiang, G; Liu, F; Moller, DE; Zhang, BB | 1 |
| Djordjevic, V; Ivic, M; Mitic-Zlatkovic, M; Stefanovic, V; Vlahovic, P | 1 |
| Fiedler, H; Häring, HU; Lehmann, R; Müssig, K; Schleicher, ED; Staiger, H; Weigert, C | 1 |
| Downes, CP; Gray, A; Jørgensen, CH; Nawaratne, R; Sethi, JK; Siddle, K | 1 |
| Kaneko, S; Koike, N; Takamura, T | 1 |
| Chang, YC; Jin, UH; Kang, YJ; Kim, CH | 1 |
| Danielsen, AG; Hosomi, Y; Liu, F; Roth, RA; Shii, K | 1 |
| Ju, HS; Matthews, K; Matthews, R; Pettit, F; Shive, W; Topek, NH; Tu, KY | 1 |
| Frevert, EU; Kahn, BB | 1 |
| Le Marchand-Brustel, Y; Ricort, JM; Tanti, JF; Van Obberghen, E | 1 |
| Bryant, WO; Carey, JO; deVente, JE; Pettit, GJ; Ways, DK | 1 |
| Benito, M; Lorenzo, M; Teruel, T; Valverde, AM | 1 |
| Barthel, A; Dandekar, AA; Nakatani, K; Roth, RA | 1 |
| Ishizawa, M; Ishizuka, T; Itaya, S; Kajita, K; Kanoh, Y; Kimura, M; Miura, A; Yasuda, K | 1 |
| Bossenmaier, B; Häring, HU; Hennige, AM; Kellerer, M; Klein, HH; Krützfeldt, J; Lammers, R; Strack, V | 1 |
| Bonaventura, V; Caimi, G; Canino, B; Lo Presti, R; Montana, M; Scarpitta, AM; Sinagra, D | 1 |
| Kitahara, M; Naitoh, T; Tsuruzoe, N | 1 |
| Broch, M; Castro, A; Engel, P; Fernandez-Real, JM; Lainez, B; Peñarroja, G; Pérez, A; Ricart, W; Richart, C; Rigla, M; Vendrell, J | 1 |
| Caro, JF; Jenquin, M; Long, S | 1 |
| Ermel, B; Häring, HU; Kellerer, M; Mühlhöfer, A; Müller, HK; Obermaier-Kusser, B; Vogt, B | 1 |
| Biemer, E; Ermel, B; Häring, HU; Kirsch, D; Machicao, F; Mushack, J; Obermaier, B; Rattenhuber, E | 1 |
| Capeau, J; Caron, M; Cherqui, G; Lascols, O; Picard, J; Wicek, D | 1 |
| Jeanrenaud, B; Lang, U; Vallotton, MB; van de Werve, G; Zaninetti, D | 1 |
31 other study(ies) available for tetradecanoylphorbol acetate and Insulin Sensitivity
| Article | Year |
|---|---|
Lauric acid alleviates insulin resistance by improving mitochondrial biogenesis in THP-1 macrophages.
Topics: Adenosine Triphosphate; Biological Transport; Cell Differentiation; DNA-Binding Proteins; Dose-Response Relationship, Drug; Gene Expression Regulation; Glucose; Glucose Transporter Type 1; Glucose Transporter Type 3; Humans; Hypoglycemic Agents; Insulin Resistance; Lauric Acids; Macrophages; Mitochondria; Mitochondrial Proteins; Organelle Biogenesis; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; PPAR gamma; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; THP-1 Cells; Transcription Factors | 2020 |
Pleiotropic Effects of Chronic Phorbol Ester Treatment to Improve Glucose Transport in Insulin-Resistant Cardiomyocytes.
Topics: Animals; Focal Adhesion Kinase 1; Glucose; Insulin Resistance; Male; Myocytes, Cardiac; Protein Kinase C; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 2017 |
Protein Kinase C Attenuates Insulin Signalling Cascade in Insulin-Sensitive and Insulin-Resistant Neuro-2a Cells.
Topics: Animals; Cell Line, Tumor; Enzyme Activation; Glucose; Glycogen Synthase Kinase 3 beta; Insulin; Insulin Resistance; Mice; Nerve Tissue Proteins; Neuroblastoma; Neurons; Protein Kinase C; Proto-Oncogene Proteins c-akt; Signal Transduction; Tetradecanoylphorbol Acetate | 2019 |
Serine phosphorylation sites on IRS2 activated by angiotensin II and protein kinase C to induce selective insulin resistance in endothelial cells.
Topics: Angiotensin II; Animals; Cattle; Cell Line; Endothelial Cells; Enzyme Activation; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Male; Mice; Mice, Transgenic; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Kinase C; Protein Kinase C beta; Rats; Rats, Zucker; Serine; Tetradecanoylphorbol Acetate; Threonine; Tyrosine | 2013 |
T-cell recruitment and Th1 polarization in adipose tissue during diet-induced obesity in C57BL/6 mice.
Topics: Adipose Tissue; Animals; CD11c Antigen; CD3 Complex; CD8-Positive T-Lymphocytes; Chemokine CCL5; Dietary Fats; Gene Expression; Inflammation; Insulin Resistance; Interferon-gamma; Interleukin-12 Subunit p40; Lymphocyte Activation; Macrophages; Male; Mice; Mice, Inbred C57BL; Obesity; T-Lymphocytes; Tetradecanoylphorbol Acetate; Th1 Cells | 2010 |
Suppression of free fatty acid-induced insulin resistance by phytopolyphenols in C2C12 mouse skeletal muscle cells.
Topics: Animals; Catechin; Cell Line; Curcumin; Enzyme Activation; Fatty Acids, Nonesterified; Insulin Receptor Substrate Proteins; Insulin Resistance; Mice; Muscle, Skeletal; Palmitic Acid; Phosphorylation; Polyphenols; Protein Kinase C; Serine; Signal Transduction; Tetradecanoylphorbol Acetate | 2012 |
Phosphorylation of adaptor protein containing pleckstrin homology domain, phosphotyrosine binding domain, and leucine zipper motif 1 (APPL1) at Ser430 mediates endoplasmic reticulum (ER) stress-induced insulin resistance in hepatocytes.
Topics: Adaptor Proteins, Signal Transducing; Animals; Cell Line; Endoplasmic Reticulum Stress; Enzyme Activators; Hepatocytes; Humans; Insulin; Insulin Resistance; Isoenzymes; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Phosphorylation; Protein Kinase C-alpha; Protein Processing, Post-Translational; Serine; Signal Transduction; Tetradecanoylphorbol Acetate | 2012 |
High insulin requirements and poor metabolic control do not modify the expression, regulation and PKC mediated activation of the p21ras pathway in PBMC from type II diabetic patients.
Topics: Aged; Cell Division; Cells, Cultured; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Enzyme Activation; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Middle Aged; Mitogen-Activated Protein Kinases; Neutrophils; Protein Kinase C; Proto-Oncogene Proteins p21(ras); Tetradecanoylphorbol Acetate | 2001 |
Salicylic acid reverses phorbol 12-myristate-13-acetate (PMA)- and tumor necrosis factor alpha (TNFalpha)-induced insulin receptor substrate 1 (IRS1) serine 307 phosphorylation and insulin resistance in human embryonic kidney 293 (HEK293) cells.
Topics: Animals; Anthracenes; Cell Line; Enzyme Activation; Humans; I-kappa B Kinase; Insulin Receptor Substrate Proteins; Insulin Resistance; Isoenzymes; JNK Mitogen-Activated Protein Kinases; Kidney; Mitogen-Activated Protein Kinases; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Recombinant Proteins; Salicylic Acid; Serine; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2003 |
Lymphocyte PC-1 activity in patients on maintenance haemodialysis treated with human erythropoietin and 1-alpha-D3.
Topics: Adjuvants, Immunologic; Administration, Oral; Adult; Aged; Blood Glucose; Carcinogens; Concanavalin A; Diabetes Complications; Diabetes Mellitus, Type 2; Erythropoietin; Female; Humans; Hydroxycholecalciferols; Insulin Resistance; Kidney Failure, Chronic; Lymphocyte Activation; Lymphocytes; Male; Middle Aged; Phosphoric Diester Hydrolases; Pyrophosphatases; Recombinant Proteins; Renal Dialysis; Tetradecanoylphorbol Acetate | 2005 |
Insulin-induced stimulation of JNK and the PI 3-kinase/mTOR pathway leads to phosphorylation of serine 318 of IRS-1 in C2C12 myotubes.
Topics: Animals; Cell Line; Enzyme Activation; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; Mice; Mitogen-Activated Protein Kinase Kinases; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Protein Kinases; Serine; Tetradecanoylphorbol Acetate; TOR Serine-Threonine Kinases | 2005 |
Regulation of insulin receptor substrate 1 pleckstrin homology domain by protein kinase C: role of serine 24 phosphorylation.
Topics: 3T3-L1 Cells; Animals; Blood Proteins; Catalytic Domain; Ceramides; Humans; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Mice; Models, Molecular; NIH 3T3 Cells; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase Inhibitors; Protein Structure, Tertiary; Rats; Sequence Alignment; Sequence Homology, Amino Acid; Serine; Tetradecanoylphorbol Acetate; Transfection | 2006 |
Induction of reactive oxygen species from isolated rat glomeruli by protein kinase C activation and TNF-alpha stimulation, and effects of a phosphodiesterase inhibitor.
Topics: Animals; Carcinogens; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Enzyme Activation; Enzyme Inhibitors; Hyperglycemia; Insulin Resistance; Kidney Glomerulus; Male; Organ Culture Techniques; Oxidative Stress; Phosphoric Diester Hydrolases; Protein Kinase C; Rats; Rats, Wistar; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2007 |
Secretion of atherogenic risk factor apolipoprotein B-100 is increased by a potential mechanism of JNK/PKC-mediated insulin resistance in liver cells.
Topics: Adaptor Proteins, Signal Transducing; Apolipoprotein B-100; Carrier Proteins; Cells, Cultured; Enzyme Inhibitors; Hepatocytes; Humans; Insulin Receptor Substrate Proteins; Insulin Resistance; JNK Mitogen-Activated Protein Kinases; Lipoproteins, VLDL; Metabolic Syndrome; Phosphorylation; Protein Kinase C; Protein Serine-Threonine Kinases; Risk Factors; Serine; Tetradecanoylphorbol Acetate; Vanadates | 2008 |
Activation of protein kinase C alpha inhibits signaling by members of the insulin receptor family.
Topics: Amino Acid Sequence; Animals; Cattle; Cell Division; CHO Cells; Cricetinae; Drosophila; Enzyme Activation; GTPase-Activating Proteins; Humans; Insulin Receptor Substrate Proteins; Insulin Resistance; Insulin-Like Growth Factor I; Isoenzymes; Kinetics; Molecular Sequence Data; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Phosphotyrosine; Protein Kinase C; Proteins; Receptor, IGF Type 1; Receptor, Insulin; Recombinant Proteins; Sequence Homology, Amino Acid; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection; Tyrosine | 1995 |
Glycerol-3-phosphate dehydrogenase activity in human lymphocytes: effects of insulin, obesity and weight loss.
Topics: Diet, Reducing; Diglycerides; Female; Gene Expression; Glycerolphosphate Dehydrogenase; Humans; Insulin; Insulin Resistance; Kinetics; Male; Middle Aged; Obesity; Reference Values; RNA Probes; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Weight Loss | 1995 |
Protein kinase C isoforms epsilon, eta, delta and zeta in murine adipocytes: expression, subcellular localization and tissue-specific regulation in insulin-resistant states.
Topics: 3T3 Cells; Adipocytes; Adipose Tissue; Animals; Cell Differentiation; Cell Fractionation; Cell Membrane; Cells, Cultured; Cytosol; Diet; Gene Expression Regulation, Enzymologic; Insulin Resistance; Isoenzymes; Mice; Mice, Inbred Strains; Obesity; Protein Kinase C; Protein Kinase C-delta; Protein Kinase C-epsilon; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 1996 |
Alterations in insulin signalling pathway induced by prolonged insulin treatment of 3T3-L1 adipocytes.
Topics: 3T3 Cells; Adipocytes; Androstadienes; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Inhibitors; Glucose; Glucose Transporter Type 4; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Kinetics; Mice; Monosaccharide Transport Proteins; Muscle Proteins; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Phosphotyrosine; Signal Transduction; Tetradecanoylphorbol Acetate; Wortmannin | 1995 |
Transcriptional regulation of insulin receptor substrate 1 by protein kinase C.
Topics: Animals; Antineoplastic Agents; Bryostatins; Down-Regulation; Enzyme Activation; Female; Humans; Insulin Receptor Substrate Proteins; Insulin Resistance; Isoenzymes; Lactones; Macrolides; Mice; Phosphoproteins; Protein Kinase C; Protein Kinase C-delta; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 1996 |
Alterations in the insulin signaling pathway induced by immortalization and H-ras transformation of brown adipocytes.
Topics: Adipocytes; Adipose Tissue, Brown; Alkaline Phosphatase; Animals; Blotting, Western; Cell Line, Transformed; Dose-Response Relationship, Drug; Fetus; Guanosine Triphosphate; Insulin; Insulin Resistance; Phosphorylation; Precipitin Tests; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Proto-Oncogene Proteins p21(ras); Rats; Rats, Wistar; Receptor, Insulin; Serine; Signal Transduction; Tetradecanoylphorbol Acetate; Threonine; Transfection | 1997 |
Protein kinase C modulates the insulin-stimulated increase in Akt1 and Akt3 activity in 3T3-L1 adipocytes.
Topics: 3T3 Cells; Adipocytes; Animals; Enzyme Activation; Gene Expression Regulation; Insulin; Insulin Antagonists; Insulin Resistance; Mice; Protein Kinase C; Protein Serine-Threonine Kinases; RNA, Messenger; Tetradecanoylphorbol Acetate | 1998 |
Effect of tumor necrosis factor-alpha on insulin signal transduction in rat adipocytes: relation to PKCbeta and zeta translocation.
Topics: Adipocytes; Animals; Cell Membrane; Cytosol; Glucose; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Isoenzymes; Male; Phosphoproteins; Protein Kinase C; Protein Kinase C beta; Protein-Tyrosine Kinases; Rats; Rats, Wistar; Receptor, Insulin; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1999 |
Serine residues 994 and 1023/25 are important for insulin receptor kinase inhibition by protein kinase C isoforms beta2 and theta.
Topics: Adenosine Triphosphate; Alanine; Cell Line; Humans; Insulin Resistance; Isoenzymes; Phosphorylation; Point Mutation; Protein Kinase C; Receptor, Insulin; Serine; Signal Transduction; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Transfection | 2000 |
Polymorphonuclear leukocyte membrane fluidity before and after activation in subjects with insulin resistance.
Topics: Adolescent; Adult; Child; Diabetes Mellitus, Type 2; Female; Glucose Clamp Technique; Glucose Intolerance; Humans; Hyperinsulinism; In Vitro Techniques; Insulin Resistance; Male; Membrane Fluidity; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Obesity; Reference Values; Tetradecanoylphorbol Acetate | 2000 |
Tumor necrosis factor-alpha is induced through phorbol ester--and glycated human albumin-dependent pathway in THP-1 cells.
Topics: Carcinogens; Catalase; Cell Differentiation; Cell Line; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Glycated Serum Albumin; Glycation End Products, Advanced; Humans; Insulin Resistance; Mitogen-Activated Protein Kinases; Monocytes; Protein Kinase C; Serum Albumin; Signal Transduction; Staurosporine; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2001 |
Shedding of TNF-alpha receptors, blood pressure, and insulin sensitivity in type 2 diabetes mellitus.
Topics: Adult; Aged; Antigens, CD; Blood Pressure; Body Mass Index; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Flow Cytometry; Humans; Insulin; Insulin Resistance; Male; Middle Aged; Monocytes; Nitroglycerin; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type I; Receptors, Tumor Necrosis Factor, Type II; Solubility; Tetradecanoylphorbol Acetate; Vasodilation | 2002 |
Effects of phorbol esters on insulin receptor function and insulin action in hepatocytes: evidence for heterogeneity.
Topics: Animals; Cells, Cultured; Diabetes Mellitus, Type 2; Insulin; Insulin Resistance; Liver; Male; Models, Biological; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Receptor, Insulin; Signal Transduction; Tetradecanoylphorbol Acetate | 1992 |
Prevention by protein kinase C inhibitors of glucose-induced insulin-receptor tyrosine kinase resistance in rat fat cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adipose Tissue; Alkaloids; Animals; Blotting, Western; Cells, Cultured; Glucose; Hypoglycemia; Insulin; Insulin Resistance; Isoquinolines; Male; Phosphorylation; Piperazines; Polymyxin B; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Rats, Inbred Strains; Receptor, Insulin; Staurosporine; Tetradecanoylphorbol Acetate | 1991 |
Catecholamines and tumour promoting phorbolesters inhibit insulin receptor kinase and induce insulin resistance in isolated human adipocytes.
Topics: 3-O-Methylglucose; Adenosine Triphosphate; Adipose Tissue; Biological Transport; Humans; Insulin; Insulin Resistance; Isoproterenol; Methylglucosides; Phosphorylation; Protein-Tyrosine Kinases; Receptor, Insulin; Tetradecanoylphorbol Acetate | 1987 |
Decreased insulin responsiveness in fat cells rendered protein kinase C-deficient by a treatment with a phorbol ester.
Topics: Adipose Tissue; Animals; Biological Transport; Deoxyglucose; Insulin; Insulin Resistance; Lipids; Male; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate | 1987 |
Identification of a major defect in insulin-resistant tissues of genetically obese (fa/fa) rats. Impaired protein kinase C.
Topics: 3-O-Methylglucose; Animals; Dose-Response Relationship, Drug; Female; Insulin Resistance; Methylglucosides; Myocardium; Obesity; Protein Kinase C; Rats; Rats, Mutant Strains; Rats, Zucker; Tetradecanoylphorbol Acetate | 1987 |