Page last updated: 2024-08-23

tetradecanoylphorbol acetate and Insulin Resistance

tetradecanoylphorbol acetate has been researched along with Insulin Resistance in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19903 (9.68)18.7374
1990's10 (32.26)18.2507
2000's11 (35.48)29.6817
2010's6 (19.35)24.3611
2020's1 (3.23)2.80

Authors

AuthorsStudies
Chew, CH; Choo, QC; Muhammad, TST; Tham, YY1
Khoramdin, B; Montessuit, C; Praplan, G; Viglino, C1
Dey, CS; Mishra, D1
D'Aquino, K; Feener, EP; King, GL; Li, Q; Maeda, Y; Mima, A; Mizutani, K; Park, K; Rask-Madsen, C; White, MF; Winnay, J1
Bennett, G; DeFuria, J; Greenberg, AS; Obin, MS; Shaul, ME; Strissel, KJ1
Chang, TW; Deng, YT; Lee, MS; Lin, JK1
Dong, LQ; Holmes, BM; Hu, D; Langlais, PR; Lee, H; Liu, M; Riojas, RA; Villarreal, R; Wei, L; Yang, X; Zhou, L1
Aharoni, D; Buchs, A; Elberg, G; Katz, Y; Levi, O; Mor, A; Ramot, Y; Rapoport, MJ; Weiss, M; Weissgarten, J1
Dallas-Yang, Q; Jiang, G; Liu, F; Moller, DE; Zhang, BB1
Djordjevic, V; Ivic, M; Mitic-Zlatkovic, M; Stefanovic, V; Vlahovic, P1
Fiedler, H; Häring, HU; Lehmann, R; Müssig, K; Schleicher, ED; Staiger, H; Weigert, C1
Downes, CP; Gray, A; Jørgensen, CH; Nawaratne, R; Sethi, JK; Siddle, K1
Kaneko, S; Koike, N; Takamura, T1
Chang, YC; Jin, UH; Kang, YJ; Kim, CH1
Danielsen, AG; Hosomi, Y; Liu, F; Roth, RA; Shii, K1
Ju, HS; Matthews, K; Matthews, R; Pettit, F; Shive, W; Topek, NH; Tu, KY1
Frevert, EU; Kahn, BB1
Le Marchand-Brustel, Y; Ricort, JM; Tanti, JF; Van Obberghen, E1
Bryant, WO; Carey, JO; deVente, JE; Pettit, GJ; Ways, DK1
Benito, M; Lorenzo, M; Teruel, T; Valverde, AM1
Barthel, A; Dandekar, AA; Nakatani, K; Roth, RA1
Ishizawa, M; Ishizuka, T; Itaya, S; Kajita, K; Kanoh, Y; Kimura, M; Miura, A; Yasuda, K1
Bossenmaier, B; Häring, HU; Hennige, AM; Kellerer, M; Klein, HH; Krützfeldt, J; Lammers, R; Strack, V1
Bonaventura, V; Caimi, G; Canino, B; Lo Presti, R; Montana, M; Scarpitta, AM; Sinagra, D1
Kitahara, M; Naitoh, T; Tsuruzoe, N1
Broch, M; Castro, A; Engel, P; Fernandez-Real, JM; Lainez, B; Peñarroja, G; Pérez, A; Ricart, W; Richart, C; Rigla, M; Vendrell, J1
Caro, JF; Jenquin, M; Long, S1
Ermel, B; Häring, HU; Kellerer, M; Mühlhöfer, A; Müller, HK; Obermaier-Kusser, B; Vogt, B1
Biemer, E; Ermel, B; Häring, HU; Kirsch, D; Machicao, F; Mushack, J; Obermaier, B; Rattenhuber, E1
Capeau, J; Caron, M; Cherqui, G; Lascols, O; Picard, J; Wicek, D1
Jeanrenaud, B; Lang, U; Vallotton, MB; van de Werve, G; Zaninetti, D1

Other Studies

31 other study(ies) available for tetradecanoylphorbol acetate and Insulin Resistance

ArticleYear
Lauric acid alleviates insulin resistance by improving mitochondrial biogenesis in THP-1 macrophages.
    Molecular biology reports, 2020, Volume: 47, Issue:12

    Topics: Adenosine Triphosphate; Biological Transport; Cell Differentiation; DNA-Binding Proteins; Dose-Response Relationship, Drug; Gene Expression Regulation; Glucose; Glucose Transporter Type 1; Glucose Transporter Type 3; Humans; Hypoglycemic Agents; Insulin Resistance; Lauric Acids; Macrophages; Mitochondria; Mitochondrial Proteins; Organelle Biogenesis; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; PPAR gamma; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; THP-1 Cells; Transcription Factors

2020
Pleiotropic Effects of Chronic Phorbol Ester Treatment to Improve Glucose Transport in Insulin-Resistant Cardiomyocytes.
    Journal of cellular biochemistry, 2017, Volume: 118, Issue:12

    Topics: Animals; Focal Adhesion Kinase 1; Glucose; Insulin Resistance; Male; Myocytes, Cardiac; Protein Kinase C; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate

2017
Protein Kinase C Attenuates Insulin Signalling Cascade in Insulin-Sensitive and Insulin-Resistant Neuro-2a Cells.
    Journal of molecular neuroscience : MN, 2019, Volume: 69, Issue:3

    Topics: Animals; Cell Line, Tumor; Enzyme Activation; Glucose; Glycogen Synthase Kinase 3 beta; Insulin; Insulin Resistance; Mice; Nerve Tissue Proteins; Neuroblastoma; Neurons; Protein Kinase C; Proto-Oncogene Proteins c-akt; Signal Transduction; Tetradecanoylphorbol Acetate

2019
Serine phosphorylation sites on IRS2 activated by angiotensin II and protein kinase C to induce selective insulin resistance in endothelial cells.
    Molecular and cellular biology, 2013, Volume: 33, Issue:16

    Topics: Angiotensin II; Animals; Cattle; Cell Line; Endothelial Cells; Enzyme Activation; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Male; Mice; Mice, Transgenic; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Kinase C; Protein Kinase C beta; Rats; Rats, Zucker; Serine; Tetradecanoylphorbol Acetate; Threonine; Tyrosine

2013
T-cell recruitment and Th1 polarization in adipose tissue during diet-induced obesity in C57BL/6 mice.
    Obesity (Silver Spring, Md.), 2010, Volume: 18, Issue:10

    Topics: Adipose Tissue; Animals; CD11c Antigen; CD3 Complex; CD8-Positive T-Lymphocytes; Chemokine CCL5; Dietary Fats; Gene Expression; Inflammation; Insulin Resistance; Interferon-gamma; Interleukin-12 Subunit p40; Lymphocyte Activation; Macrophages; Male; Mice; Mice, Inbred C57BL; Obesity; T-Lymphocytes; Tetradecanoylphorbol Acetate; Th1 Cells

2010
Suppression of free fatty acid-induced insulin resistance by phytopolyphenols in C2C12 mouse skeletal muscle cells.
    Journal of agricultural and food chemistry, 2012, Feb-01, Volume: 60, Issue:4

    Topics: Animals; Catechin; Cell Line; Curcumin; Enzyme Activation; Fatty Acids, Nonesterified; Insulin Receptor Substrate Proteins; Insulin Resistance; Mice; Muscle, Skeletal; Palmitic Acid; Phosphorylation; Polyphenols; Protein Kinase C; Serine; Signal Transduction; Tetradecanoylphorbol Acetate

2012
Phosphorylation of adaptor protein containing pleckstrin homology domain, phosphotyrosine binding domain, and leucine zipper motif 1 (APPL1) at Ser430 mediates endoplasmic reticulum (ER) stress-induced insulin resistance in hepatocytes.
    The Journal of biological chemistry, 2012, Jul-27, Volume: 287, Issue:31

    Topics: Adaptor Proteins, Signal Transducing; Animals; Cell Line; Endoplasmic Reticulum Stress; Enzyme Activators; Hepatocytes; Humans; Insulin; Insulin Resistance; Isoenzymes; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Phosphorylation; Protein Kinase C-alpha; Protein Processing, Post-Translational; Serine; Signal Transduction; Tetradecanoylphorbol Acetate

2012
High insulin requirements and poor metabolic control do not modify the expression, regulation and PKC mediated activation of the p21ras pathway in PBMC from type II diabetic patients.
    International journal of experimental diabetes research, 2001, Volume: 2, Issue:1

    Topics: Aged; Cell Division; Cells, Cultured; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Enzyme Activation; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Middle Aged; Mitogen-Activated Protein Kinases; Neutrophils; Protein Kinase C; Proto-Oncogene Proteins p21(ras); Tetradecanoylphorbol Acetate

2001
Salicylic acid reverses phorbol 12-myristate-13-acetate (PMA)- and tumor necrosis factor alpha (TNFalpha)-induced insulin receptor substrate 1 (IRS1) serine 307 phosphorylation and insulin resistance in human embryonic kidney 293 (HEK293) cells.
    The Journal of biological chemistry, 2003, Jan-03, Volume: 278, Issue:1

    Topics: Animals; Anthracenes; Cell Line; Enzyme Activation; Humans; I-kappa B Kinase; Insulin Receptor Substrate Proteins; Insulin Resistance; Isoenzymes; JNK Mitogen-Activated Protein Kinases; Kidney; Mitogen-Activated Protein Kinases; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Recombinant Proteins; Salicylic Acid; Serine; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

2003
Lymphocyte PC-1 activity in patients on maintenance haemodialysis treated with human erythropoietin and 1-alpha-D3.
    Annals of clinical biochemistry, 2005, Volume: 42, Issue:Pt 1

    Topics: Adjuvants, Immunologic; Administration, Oral; Adult; Aged; Blood Glucose; Carcinogens; Concanavalin A; Diabetes Complications; Diabetes Mellitus, Type 2; Erythropoietin; Female; Humans; Hydroxycholecalciferols; Insulin Resistance; Kidney Failure, Chronic; Lymphocyte Activation; Lymphocytes; Male; Middle Aged; Phosphoric Diester Hydrolases; Pyrophosphatases; Recombinant Proteins; Renal Dialysis; Tetradecanoylphorbol Acetate

2005
Insulin-induced stimulation of JNK and the PI 3-kinase/mTOR pathway leads to phosphorylation of serine 318 of IRS-1 in C2C12 myotubes.
    Biochemical and biophysical research communications, 2005, Sep-30, Volume: 335, Issue:3

    Topics: Animals; Cell Line; Enzyme Activation; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; Mice; Mitogen-Activated Protein Kinase Kinases; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Protein Kinases; Serine; Tetradecanoylphorbol Acetate; TOR Serine-Threonine Kinases

2005
Regulation of insulin receptor substrate 1 pleckstrin homology domain by protein kinase C: role of serine 24 phosphorylation.
    Molecular endocrinology (Baltimore, Md.), 2006, Volume: 20, Issue:8

    Topics: 3T3-L1 Cells; Animals; Blood Proteins; Catalytic Domain; Ceramides; Humans; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Mice; Models, Molecular; NIH 3T3 Cells; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase Inhibitors; Protein Structure, Tertiary; Rats; Sequence Alignment; Sequence Homology, Amino Acid; Serine; Tetradecanoylphorbol Acetate; Transfection

2006
Induction of reactive oxygen species from isolated rat glomeruli by protein kinase C activation and TNF-alpha stimulation, and effects of a phosphodiesterase inhibitor.
    Life sciences, 2007, Apr-10, Volume: 80, Issue:18

    Topics: Animals; Carcinogens; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Enzyme Activation; Enzyme Inhibitors; Hyperglycemia; Insulin Resistance; Kidney Glomerulus; Male; Organ Culture Techniques; Oxidative Stress; Phosphoric Diester Hydrolases; Protein Kinase C; Rats; Rats, Wistar; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

2007
Secretion of atherogenic risk factor apolipoprotein B-100 is increased by a potential mechanism of JNK/PKC-mediated insulin resistance in liver cells.
    Journal of cellular biochemistry, 2008, Feb-15, Volume: 103, Issue:3

    Topics: Adaptor Proteins, Signal Transducing; Apolipoprotein B-100; Carrier Proteins; Cells, Cultured; Enzyme Inhibitors; Hepatocytes; Humans; Insulin Receptor Substrate Proteins; Insulin Resistance; JNK Mitogen-Activated Protein Kinases; Lipoproteins, VLDL; Metabolic Syndrome; Phosphorylation; Protein Kinase C; Protein Serine-Threonine Kinases; Risk Factors; Serine; Tetradecanoylphorbol Acetate; Vanadates

2008
Activation of protein kinase C alpha inhibits signaling by members of the insulin receptor family.
    The Journal of biological chemistry, 1995, Sep-15, Volume: 270, Issue:37

    Topics: Amino Acid Sequence; Animals; Cattle; Cell Division; CHO Cells; Cricetinae; Drosophila; Enzyme Activation; GTPase-Activating Proteins; Humans; Insulin Receptor Substrate Proteins; Insulin Resistance; Insulin-Like Growth Factor I; Isoenzymes; Kinetics; Molecular Sequence Data; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Phosphotyrosine; Protein Kinase C; Proteins; Receptor, IGF Type 1; Receptor, Insulin; Recombinant Proteins; Sequence Homology, Amino Acid; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection; Tyrosine

1995
Glycerol-3-phosphate dehydrogenase activity in human lymphocytes: effects of insulin, obesity and weight loss.
    Biochemical and biophysical research communications, 1995, Feb-06, Volume: 207, Issue:1

    Topics: Diet, Reducing; Diglycerides; Female; Gene Expression; Glycerolphosphate Dehydrogenase; Humans; Insulin; Insulin Resistance; Kinetics; Male; Middle Aged; Obesity; Reference Values; RNA Probes; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Weight Loss

1995
Protein kinase C isoforms epsilon, eta, delta and zeta in murine adipocytes: expression, subcellular localization and tissue-specific regulation in insulin-resistant states.
    The Biochemical journal, 1996, Jun-15, Volume: 316 ( Pt 3)

    Topics: 3T3 Cells; Adipocytes; Adipose Tissue; Animals; Cell Differentiation; Cell Fractionation; Cell Membrane; Cells, Cultured; Cytosol; Diet; Gene Expression Regulation, Enzymologic; Insulin Resistance; Isoenzymes; Mice; Mice, Inbred Strains; Obesity; Protein Kinase C; Protein Kinase C-delta; Protein Kinase C-epsilon; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate

1996
Alterations in insulin signalling pathway induced by prolonged insulin treatment of 3T3-L1 adipocytes.
    Diabetologia, 1995, Volume: 38, Issue:10

    Topics: 3T3 Cells; Adipocytes; Androstadienes; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Inhibitors; Glucose; Glucose Transporter Type 4; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Kinetics; Mice; Monosaccharide Transport Proteins; Muscle Proteins; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Phosphotyrosine; Signal Transduction; Tetradecanoylphorbol Acetate; Wortmannin

1995
Transcriptional regulation of insulin receptor substrate 1 by protein kinase C.
    The Journal of biological chemistry, 1996, Dec-13, Volume: 271, Issue:50

    Topics: Animals; Antineoplastic Agents; Bryostatins; Down-Regulation; Enzyme Activation; Female; Humans; Insulin Receptor Substrate Proteins; Insulin Resistance; Isoenzymes; Lactones; Macrolides; Mice; Phosphoproteins; Protein Kinase C; Protein Kinase C-delta; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured

1996
Alterations in the insulin signaling pathway induced by immortalization and H-ras transformation of brown adipocytes.
    Endocrinology, 1997, Volume: 138, Issue:8

    Topics: Adipocytes; Adipose Tissue, Brown; Alkaline Phosphatase; Animals; Blotting, Western; Cell Line, Transformed; Dose-Response Relationship, Drug; Fetus; Guanosine Triphosphate; Insulin; Insulin Resistance; Phosphorylation; Precipitin Tests; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Proto-Oncogene Proteins p21(ras); Rats; Rats, Wistar; Receptor, Insulin; Serine; Signal Transduction; Tetradecanoylphorbol Acetate; Threonine; Transfection

1997
Protein kinase C modulates the insulin-stimulated increase in Akt1 and Akt3 activity in 3T3-L1 adipocytes.
    Biochemical and biophysical research communications, 1998, Feb-13, Volume: 243, Issue:2

    Topics: 3T3 Cells; Adipocytes; Animals; Enzyme Activation; Gene Expression Regulation; Insulin; Insulin Antagonists; Insulin Resistance; Mice; Protein Kinase C; Protein Serine-Threonine Kinases; RNA, Messenger; Tetradecanoylphorbol Acetate

1998
Effect of tumor necrosis factor-alpha on insulin signal transduction in rat adipocytes: relation to PKCbeta and zeta translocation.
    Biochimica et biophysica acta, 1999, Apr-01, Volume: 1449, Issue:3

    Topics: Adipocytes; Animals; Cell Membrane; Cytosol; Glucose; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Isoenzymes; Male; Phosphoproteins; Protein Kinase C; Protein Kinase C beta; Protein-Tyrosine Kinases; Rats; Rats, Wistar; Receptor, Insulin; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

1999
Serine residues 994 and 1023/25 are important for insulin receptor kinase inhibition by protein kinase C isoforms beta2 and theta.
    Diabetologia, 2000, Volume: 43, Issue:4

    Topics: Adenosine Triphosphate; Alanine; Cell Line; Humans; Insulin Resistance; Isoenzymes; Phosphorylation; Point Mutation; Protein Kinase C; Receptor, Insulin; Serine; Signal Transduction; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Transfection

2000
Polymorphonuclear leukocyte membrane fluidity before and after activation in subjects with insulin resistance.
    Acta diabetologica, 2000, Volume: 37, Issue:1

    Topics: Adolescent; Adult; Child; Diabetes Mellitus, Type 2; Female; Glucose Clamp Technique; Glucose Intolerance; Humans; Hyperinsulinism; In Vitro Techniques; Insulin Resistance; Male; Membrane Fluidity; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Obesity; Reference Values; Tetradecanoylphorbol Acetate

2000
Tumor necrosis factor-alpha is induced through phorbol ester--and glycated human albumin-dependent pathway in THP-1 cells.
    Cellular signalling, 2001, Volume: 13, Issue:5

    Topics: Carcinogens; Catalase; Cell Differentiation; Cell Line; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Glycated Serum Albumin; Glycation End Products, Advanced; Humans; Insulin Resistance; Mitogen-Activated Protein Kinases; Monocytes; Protein Kinase C; Serum Albumin; Signal Transduction; Staurosporine; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

2001
Shedding of TNF-alpha receptors, blood pressure, and insulin sensitivity in type 2 diabetes mellitus.
    American journal of physiology. Endocrinology and metabolism, 2002, Volume: 282, Issue:4

    Topics: Adult; Aged; Antigens, CD; Blood Pressure; Body Mass Index; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Flow Cytometry; Humans; Insulin; Insulin Resistance; Male; Middle Aged; Monocytes; Nitroglycerin; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type I; Receptors, Tumor Necrosis Factor, Type II; Solubility; Tetradecanoylphorbol Acetate; Vasodilation

2002
Effects of phorbol esters on insulin receptor function and insulin action in hepatocytes: evidence for heterogeneity.
    Molecular and cellular biochemistry, 1992, Feb-12, Volume: 109, Issue:2

    Topics: Animals; Cells, Cultured; Diabetes Mellitus, Type 2; Insulin; Insulin Resistance; Liver; Male; Models, Biological; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Receptor, Insulin; Signal Transduction; Tetradecanoylphorbol Acetate

1992
Prevention by protein kinase C inhibitors of glucose-induced insulin-receptor tyrosine kinase resistance in rat fat cells.
    Diabetes, 1991, Volume: 40, Issue:11

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adipose Tissue; Alkaloids; Animals; Blotting, Western; Cells, Cultured; Glucose; Hypoglycemia; Insulin; Insulin Resistance; Isoquinolines; Male; Phosphorylation; Piperazines; Polymyxin B; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Rats, Inbred Strains; Receptor, Insulin; Staurosporine; Tetradecanoylphorbol Acetate

1991
Catecholamines and tumour promoting phorbolesters inhibit insulin receptor kinase and induce insulin resistance in isolated human adipocytes.
    Diabetologia, 1987, Volume: 30, Issue:2

    Topics: 3-O-Methylglucose; Adenosine Triphosphate; Adipose Tissue; Biological Transport; Humans; Insulin; Insulin Resistance; Isoproterenol; Methylglucosides; Phosphorylation; Protein-Tyrosine Kinases; Receptor, Insulin; Tetradecanoylphorbol Acetate

1987
Decreased insulin responsiveness in fat cells rendered protein kinase C-deficient by a treatment with a phorbol ester.
    Endocrinology, 1987, Volume: 120, Issue:5

    Topics: Adipose Tissue; Animals; Biological Transport; Deoxyglucose; Insulin; Insulin Resistance; Lipids; Male; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate

1987
Identification of a major defect in insulin-resistant tissues of genetically obese (fa/fa) rats. Impaired protein kinase C.
    Diabetes, 1987, Volume: 36, Issue:3

    Topics: 3-O-Methylglucose; Animals; Dose-Response Relationship, Drug; Female; Insulin Resistance; Methylglucosides; Myocardium; Obesity; Protein Kinase C; Rats; Rats, Mutant Strains; Rats, Zucker; Tetradecanoylphorbol Acetate

1987