tetradecanoylphorbol acetate has been researched along with Innate Inflammatory Response in 541 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 51 (9.43) | 18.7374 |
1990's | 125 (23.11) | 18.2507 |
2000's | 154 (28.47) | 29.6817 |
2010's | 190 (35.12) | 24.3611 |
2020's | 21 (3.88) | 2.80 |
Authors | Studies |
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Bocheńska, K; Gabig-Cimińska, M; Moskot, M | 1 |
Fernandez, JR; Fitzgerald, C; Perez, E; Rouzard, K; Savile, C; Tamura, M | 1 |
Feng, X; Guo, P; Hu, L; Huang, J; Li, M; Li, Y; Sun, M; Wang, X; Wu, J; Yu, H; Zeng, J; Zhang, J; Zhang, S | 1 |
Huang, MY; Stamer, UM; Stüber, F; Zhang, L | 1 |
Kawabata, H; Kawase, T; Masuki, H; Nakamura, M; Okubo, M; Sato, A; Tsujino, T; Uematsu, T; Watanabe, T | 1 |
Dong, H; Gao, P; Hao, Y; Li, W; Shi, B; Xu, M | 1 |
Kemény, Á; Kovács, L; Mackei, M; Mátis, G; Neogrády, Z; Petrilla, J; Sebők, C; Tráj, P; Vörösházi, J; Walmsley, S | 1 |
Akira, S; Morisaka, H; Sano, S; Takaishi, M | 1 |
Aziez, M; Bribi, N; Ferhat, R; Merakeb, MS; Yanat, B | 1 |
Chen, WW; Ding, ZF; Gong, WJ; Han, F; Hu, LH; Lu, GT; Shen, QH; Shi, XL; Wang, D; Xiao, WM; Xu, XM; Zhang, JX; Zhu, QT | 1 |
Amorim, MA; André, E; Cabrini, DA; Calixto, JB; de Lima Silva, AHB; de Mello Bandenburg, M; de Oliveira, JRJM; de Souza Oliveira, VH; Havran, WL; Lejeune, VBP; Otuki, MF; Rocha, FG; Soley, BS; Witherden, DA; Zanoveli, JM | 1 |
Collado-Diaz, V; Friess, MC; Hagedorn, O; Haghayegh Jahromi, N; Halin, C; Jadhav, M; Leroux, JC; Polomska, A; Proulx, ST; Vallone, A; Vranova, M; Willrodt, AH | 1 |
Brunini, C; Fresu, LG; Massara, E; Talmon, M | 1 |
Dahlhoff, M; Fröhlich, T; Goebeler, M; Hoesl, C; Hundt, JE; Kneitz, H; Schneider, MR; Wolf, R | 1 |
Bocci, F; Jolly, MK; Kang, TY; Levchenko, A; Levine, H; Onuchic, JN | 1 |
Choi, SY; Eum, WS; Kim, DS; Kim, DW; Kim, JS; Kim, MY; Shin, MJ; Yeo, HJ; You, JH | 1 |
Cha, HJ; Choi, SY; Choi, YJ; Eum, WS; Han, KH; Kim, DW; Lee, SH; Park, J; Shin, MJ | 1 |
Balkrishna, A; Chauhan, A; Gupta, A; Nain, P; Ranjan, R; Sharma, N; Varshney, A | 1 |
Ahmed, F; Bano, S; Chaudhary, SC; Khan, F; Samim, M | 1 |
Antonelli, A; Baccani, I; Cannatelli, A; Castronovo, G; Clemente, AM; Cozzolino, F; Giani, T; Mattiuz, G; Nicolò, S; Rossolini, GM; Tanturli, M; Torcia, MG | 1 |
Abbas, M; Altamimy, R; Amoura, L; El Habhab, A; El Itawi, H; Kassem, M; Kessler, L; Khemais-Benkhiat, S; Kreutter, G; Qureshi, AW; Schini-Kerth, VB; Toti, F; Zobairi, F | 1 |
Borges, L; Gorjão, R; Gray, SR; Hatanaka, E; Martins, TR; Momesso, CM; Pithon-Curi, TC; Santos, VC | 1 |
Franzyk, H; Hancock, REW; Masoudi, H; Skovbakke, SL; Wu, BC | 1 |
Al-Olayan, EM; Chang, SN; Cho, KH; Dey, DK; Hwang, BS; Kang, SC; Kong, WH; Oh, ST; Park, JG | 1 |
Evan Prince, S; Hiraganahalli Bhaskarmurthy, D | 1 |
Aragón, M; Castellanos, L; Costa, GM; Ospina, LF; Ramos, FA; Sepúlveda, P; Urrego, N | 1 |
Clancy, DM; Henry, CM; Martin, SJ; Sullivan, GP | 1 |
Anguish, LJ; Coonrod, SA; Horibata, S; McElwee, JL; McLean, D; Mohanan, S; Mukai, C; Sams, K; Yan, A | 1 |
Aguilar-Pimentel, JA; Beck, PJ; Fuchs, H; Gailus-Durner, V; Garman, KA; Hrabe de Angelis, M; Lee, YG; Ollert, M; Riegel, AT; Schmidt, MO; Schmidt-Weber, C; Tan, M; Tassi, E; Wellstein, A; Zuo, C | 1 |
Hancock, REW; Lee, AH; Wu, BC | 1 |
Chen, X; Kelly, CP; Koon, HW; Lee, EC; Mussatto, CC; Ortiz, C; Pothoulakis, C; Tran, DH; Wang, J | 1 |
Cao, YJ; Du, WX; Huang, YB; Liu, CF; Liu, HH; Shi, LY; Sun, JJ; Wang, F; Yin, XW; Zhang, YL | 1 |
Kang, OH; Kim, SA; Kong, R; Kwon, DY; Seo, YS; Shin, DW; Zhou, T | 1 |
Etscheid, M; Grasso, S; Kanse, SM; Lang, IM; Neumann, A; von Köckritz-Blickwede, M | 1 |
Kojima, Y; Nakamura, T; Yasoshima, M; Yoshida, N | 1 |
Liu, P; Wang, D | 1 |
Bak, Y; Hong, JT; Kim, SJ; Lee, HP; Pham, TH; Song, YS; Yoon, DY | 1 |
Hawkins, CL; Pan, GJ; Rayner, BS; van Reyk, DM; Zhang, Y | 1 |
Jeong, HJ; Kim, HM; Nam, SY | 1 |
Hyvärinen, A; Illi, S; Karvonen, AM; Kirjavainen, PV; Mustonen, K; Pekkanen, J; Pfefferle, PI; Remes, S; Renz, H; Roponen, M; Schaub, B; Tischer, C; von Mutius, E | 1 |
Jeong, WY; Kim, CW; Kim, JH | 1 |
Lai, XF; Lin, ZJ; Liu, XG; Mai, CL; Sun, SL; Tan, Z; Xu, YN; Zeng, WJ; Zhang, J; Zhou, LJ | 1 |
De Bizemont, A; Hubert, J; Humeau, A; Kaouas, A; Lambert, C; Nuzillard, JM; Renault, JH; Reynaud, R; Scandolera, A; Winkel, C | 1 |
Chew, EH; Chui, WK; Gan, FF; Hadadi, E; Karuppasamy, M; Ng, HL; Ong, SM; Seah, W; Wong, SC; Yeap, WH; Zhang, R | 1 |
Bollag, KA; Bollag, WB; Choudhary, V; Edwards, JG; Emmons, AC; Johnson, MH; Seremwe, M; Wang, A; Xie, D | 1 |
Hu, Q; Jiang, L; Li, Y; Xiao, L | 1 |
Guo, RH; Kim, YH; Kim, YR; Li, HX; Ma, JY; Su, XD; Yang, SY | 1 |
Ando, H; Fujimura, A; Kumazaki, M; Ushijima, K; Yoshioka, D | 1 |
Bigas, J; Boix, J; Carceller, E; Pérez, P; Sevilla, LM | 1 |
Cramer, LP; Cutler, DF; Grimes, W; Lopes da Silva, M; McCormack, JJ; Nightingale, TD; Robinson, C; Vaughan, A; White, IJ | 1 |
Cho, H; Kim, B; Kim, HE; Kim, O; Shi, S; Sun, Q | 1 |
Cho, SB; Cho, YJ; Choi, SY; Choi, YJ; Eum, WS; Han, KH; Hwang, JS; Jo, HS; Kim, DS; Kim, DW; Kim, HA; Kim, JA; Lee, CH; Lee, KW; Park, J; Park, JH; Shin, MJ; Yeo, EJ; Yeo, HJ; Yong, JI | 1 |
Bølling, AK; Carlsten, C; Huff, RD; Maestre-Batlle, D; Pena, OM; Randhawa, A | 1 |
Bhat, SA; Hanif, K; Shukla, R; Sood, A | 1 |
He, LP; Zhao, XS | 1 |
Chen, JN; Hu, Z; Ip, SP; Lai, XP; Lin, ZX; Su, ZR; Xian, YF | 1 |
Bak, DH; Choi, MJ; Hong, J; Kim, BJ; Kim, S; Kwon, TR; Lee, BC; Lee, E; Lee, K; Mun, SK; Na, J | 1 |
Li, Z; Liu, P; Lu, Y; Song, Y; Xie, B; Ye, X | 1 |
Maharjan, R; Sf, A | 1 |
Al Habeeb, A; Bai, X; Cho, HR; Liu, M; Lu, C; Post, A; Wang, Y; Xiang, YY | 1 |
Chen, HX; Dong, CZ; Du, ZY; Gu, YH; Li, PH; Zhang, WJ; Zhao, MC | 1 |
Du, Z; Gao, Z; Han, Y; Pan, C; Rakariyatham, K; Song, M; Tang, Z; Wu, X; Xiao, H; Yuan, B; Zhang, G | 1 |
Andersen, MN; Etzerodt, A; Grønbaek, H; Moestrup, SK; Møller, HJ; Nielsen, MC; Rittig, N; Rødgaard-Hansen, S | 1 |
He, J; Huang, N; Li, M; Lv, Q; Xie, W; Xu, N; Zhang, Y | 1 |
Cho, HJ; Han, NY; Jung, HS; Lee, MJ; Sohn, Y | 1 |
Bayer, SB; Hampton, MB; Maghzal, G; Stocker, R; Winterbourn, CC | 1 |
Deng, J; Liu, X; Qin, Z; Qu, L; Wang, C; Wang, H; Zhang, G | 1 |
Barkauskiene, D; Bieksiene, K; Jeroch, J; Lavinskiene, S; Sakalauskas, R; Vaitkus, M | 1 |
Lavinskiene, S; Miliauskas, S; Sakalauskas, R; Vaguliene, N; Zemaitis, M | 1 |
Chen, HC; Lin, JA; Yen, GC | 1 |
Dong, YC; Hu, MH; Jia, XZ; Li, Y; Lin, QY; Ren, H; Wang, CY; Xu, HW; Yuan, HP; Zhang, FY; Zhang, WH; Zhao, RB; Zheng, QF; Zhou, JH | 1 |
Brown, GC; Hornik, TC; Neniskyte, U | 1 |
Aragón, M; Castellanos, L; Ospina, LF; Ramos, FA; Reina, E | 1 |
Barmak, MJ; Mehraban, F; Mostafazadeh, M; Naderian, M; Sadeghi, H; Talebianpoor, MS | 1 |
Jung, YG; Kim, BH; Kim, S; Kim, TY; Lee, JM | 1 |
Eilertsen, J; Laskar, A; Li, W; Yuan, XM | 1 |
Chalaris, A; Etzerodt, A; Galea, I; Moestrup, SK; Møller, HJ; Rasmussen, MR; Schwarz, J; Svendsen, P | 1 |
Barman, DN; Boyanapalli, SS; Chen, L; Hu, L; Huang, MT; Kong, AN; Lee, JH; Lee, KR; Magesh, S; Su, ZY | 1 |
Ali, F; Khan, AQ; Khan, R; Lateef, MA; Maqbool, T; Sultana, S | 1 |
Ali, F; Hamiza, OO; Hasan, SK; Khan, AQ; Khan, R; Lateef, A; Rehman, MU; Sultana, S; Tahir, M | 1 |
Olsen, JO; Østerud, B | 1 |
Baban, B; Chandler, P; DuHadaway, JB; Keough, MP; Mandik-Nayak, L; Mellor, AL; Merlo, LM; Metz, R; Muller, AJ; Pigott, E; Prendergast, GC; Rust, S; Smith, C | 1 |
Hogg, N; McNeill, E | 1 |
Assa, A; Glogauer, M; Lorentz, RJ; Sherman, PM; Vong, L | 1 |
Guan, X; Guo, J; Han, Q; Li, B; Wang, L; Zhang, H; Zhang, M; Zhou, J | 1 |
Chen, Z; Gao, D; Hu, Y; Ma, L; Tian, X; Wang, G; Yao, J; Zhai, X | 1 |
Jeong, HJ; Kim, HM; Kim, MH; Seo, JH | 1 |
Arasa, J; Martos, P; Montesinos, MC; Terencio, MC; Valcuende-Cavero, F | 1 |
Eric, S; Francis, F; François, LJ; Henri, VP; Laurent, P; Makon-Sébastien, N; Serge, C; Yves, B | 1 |
Chou, Y; Chu, CQ; Jiang, Y; Jiang, Z; Zhao, L | 1 |
Alvarez, L; Arellano-García, J; Castillo-España, P; Garduño-Ramírez, ML; Marquina, S; Perea-Arango, I; Salinas, R; Zamilpa, A | 1 |
Jeong, KT; Kim, SG; Lee, E; Lee, J; Lee, YJ; Park, HH; Park, NY; Park, YN | 1 |
Cónsole, G; Giner, RM; Neyret, E; Prieto, JM; Ríos, JL; Schinella, G; Tournier, H | 1 |
Hart, RP; Huang, MT; Huang, Y; Kong, AN; Lee, JH; Lu, Y; Pung, D; Ramirez, C; Shu, L; Su, ZY; Verzi, M; Yang, AY; Zhang, C | 1 |
Beloqui, O; Benito-Martin, A; Blanco-Colio, LM; Burillo, E; Egido, J; Fernandez-Garcia, CE; Lindholt, JS; Llamas-Granda, P; Madrigal-Matute, J; Martin-Ventura, JL; Ortiz, A; Zalba, G | 1 |
Cheng, YT; Ho, CY; Jhang, JJ; Yen, GC | 1 |
Chen, CL; Hong, MY; Hsieh, CY; Lin, CF; Lin, YS; Tsai, TT; Yeh, TM | 1 |
Alexandre-Pires, G; Brito, P; Carneiro, C; Ferreira-Dias, G; Galvão, A; Leitão, A; Nunes, T; Pereira, C; Rebordão, MR; Vilela, C | 1 |
Cho, SB; Cho, SW; Choi, SY; Choi, YJ; Eum, WS; Han, KH; Jo, HS; Kim, DS; Kim, DW; Kim, HA; Kim, HR; Kim, ST; Lee, CH; Park, J; Park, JH; Park, SY; Yeo, EJ; Yu, YH | 1 |
Kataoka, S; Kitaba, S; Magata, Y; Nakajima, K; Sano, S; Takaishi, M; Yamamoto, M | 1 |
Birchmeier, W; Iwata, T; Okano, T; Takai, Y; Yamato, M; Yoshida, T | 1 |
Kundu, JK; Li, J; Liu, L; Surh, YJ | 1 |
Cho, HJ; Choi, MS; Jung, JI; Jung, YJ; Kang, YH; Park, JH; Sung, MK; Yu, R | 1 |
Bae, ON; Bae, S; Kim, ES; Koo, JE; Lee, JY; Lim, KM | 1 |
Del-Ángel, M; Delgado, G; Nieto, A; Ramírez-Apan, T | 1 |
Cao, J; Chen, A; Huang, K; Song, Z; Xu, H; Yin, Y; Zhang, X | 1 |
Choi, H; Hui, Z; Im, Y; Jeon, S; Kim, C; Kim, J; Kim, O; Kim, S; Kim, Y; Lim, W | 1 |
Hu, J; Jin, H; Sun, J; Zhao, Y | 1 |
Elisia, I; Kitts, DD | 1 |
Kawamura, M; Kuramochi, K; Kuriyama, I; Mizushina, Y; Naganune, H; Onodera, T; Sakamoto, Y; Tabata, A; Tsubaki, K | 1 |
Anders, J; Blumenberg, M; Cataisson, C; Efimova, T; Kiss, A; Koppel, AC; Yuspa, SH | 1 |
Chen, C; Fan, F; Lin, C; Liu, Y; Liu, Z; Lu, Y; Shen, C; Sun, L; Tao, Y; Wang, A; Wang, S; Wei, Z; Wu, H; Zhao, L; Zhu, P; Zhu, Z | 1 |
Cao, Y; Chen, C; Fan, F; Lin, C; Liu, Z; Lu, Y; Shan, Y; Shen, C; Sun, L; Tao, Y; Wang, A; Wang, S; Wei, Z; Wu, H; Zheng, S; Zhu, P | 1 |
Capó, X; Martorell, M; Pons, A; Sureda, A; Tur, JA | 1 |
Baron, L; Bismuth, G; Bisson, JF; Blanchard, N; Bruhns, P; Chany, AC; Demangel, C; Guenin-Macé, L; Hidalgo-Lucas, S; Jönsson, F; Le Chevalier, F; Saint-Auret, S; Tresse, C | 1 |
Carbajal, S; Cho, J; DiGiovanni, J; Junco, J; Rho, O; Siegel, D; Slaga, TJ | 1 |
Libert, C; Sklyarova, T; van Hengel, J; van Roy, F; Van Wonterghem, E; Vandenbroucke, RE | 1 |
Özören, N; Sahillioğlu, AC | 1 |
Guevara-Lora, I; Kozik, A; Niewiarowska-Sendo, A; Patrzalek, K | 1 |
Du, Z; Li, Y; Liu, W; Zhang, K; Zheng, X | 1 |
Chu, X; Gong, Z; Li, X; Wang, L; Yang, F; Zhang, H; Zhang, Q | 1 |
Bazzoli, F; Belluzzi, A; Chieco, P; D'Angelo, L; Fazio, C; Fogliano, V; Milazzo, M; Munarini, A; Napolitano, M; Piazzi, G; Prossomariti, A; Ricciardiello, L; Vitaglione, P | 1 |
Grice, ID; Hashimi, SM; Qi, J; Wei, MQ; Zulfiker, AH | 1 |
Gollavilli, PN; Gopoju, R; Karnewar, S; Kotamraju, S; Kumar, JM; Narra, SR; Vasamsetti, SB | 1 |
Fu, Y; He, X; Kou, J; Liu, W; Wang, J; Wei, Z; Yang, Z | 1 |
Akram, M; Bae, ON; Chang, SY; Kim, E; Kim, ES; Kim, JH; Kim, JK; Kim, KA; Majid, A; Noh, D; Shin, YJ | 1 |
Gu, Y; Huang, LY; Li, G; Wang, C | 1 |
Aarup, A; Christensen, JP; Hansen, PR; Hartvigsen, K; Madsen, M; Nielsen, LB; Pedersen, AE; Pedersen, TX | 1 |
Balmain, A; Del Rosario, R; Ginzinger, D; Halliwill, KD; Kang, HC; Quigley, DA | 1 |
Aoki, M; Furue, Y; Fusamae, Y; Imura, C; Okuda, T; Oshima, I; Shichijo, M; Suzuki, M; Tsujii, K; Ueyama, A; Yamamoto, M; Yasui, K | 1 |
Byun, HJ; Kang, GJ; Kim, EJ; Kim, HJ; Lee, CH; Lee, HJ; Park, MK | 1 |
Akbartabar Touri, M; Delaviz, H; Ghavamzadeh, M; Jafari Barmak, M; Parishani, M; Sadeghi, H; Zarezade, V | 1 |
Chung, WY; Hwang, YS; Lee, CK; Park, JH; Park, KK | 1 |
Bateman, A; Belaaouaj, A; Fässler, R; Fröhlich, L; Jenne, DE; Kessenbrock, K; Lämmermann, T; Ollert, M; Pfister, H; Ring, J; Sixt, M | 1 |
Chin-Dusting, J; Hoang, A; McCormick, SP; Mukhamedova, N; Murphy, AJ; Remaley, AT; Stirzaker, RA; Sviridov, D; Woollard, KJ | 1 |
Castro, R; Lamas, J; Leiro, J; Morais, P; Orallo, F; Sanmartín, ML | 1 |
O'Sullivan, AW; Redmond, HP; Wang, JH | 1 |
Chen, R; Huang, C; Jiao, B; Liu, X; Shang, Y | 1 |
Hvid, H; Kemp, K; Kvist, PH; Svensson, L; Teige, I | 1 |
Curi, R; Hatanaka, E; Lambertucci, RH; Newsholme, P; Vinolo, MA | 1 |
Katiyar, SK; Meeran, SM; Punathil, T; Vaid, M | 1 |
Alam, MS; Athar, M; Chaudhary, SC; Siddiqui, MS | 4 |
Choi, JS; Fujii, H; Hong, YK; Khan, MN; Kim, E; Lee, MC; Nam, TJ | 1 |
Burt, C; Fraser, AR; Graham, GJ; Jamieson, T; Liew, FY; McInnes, IB; McKimmie, CS; Moore, M; Nibbs, RJ; Pitman, NI; Xu, D | 1 |
Kumar, PP; Kuttan, G | 1 |
Li, Z; Qin, Z; Wang, C; Xiao, M; Zhang, J; Zhao, X | 1 |
de la Rebière, G; Deby, C; Deby-Dupont, G; Franck, T; Kohnen, S; Niesten, A; Serteyn, D | 1 |
Baek, DY; Kim, DH; Kim, JK; Kim, YH; Lim, H; Shin, HK | 1 |
Fukuda, Y; Goto, M; Hayashi, Y; Inoue, H; Kadoshima-Yamaoka, K; Kanki, S; Murafuji, H; Murakawa, M; Nagahira, K; Nakatsuka, T; Ogata, A; Tanaka, Y; Yoshioka, R | 1 |
Delporte, C; Dieguez, R; Garrido, G; Hernández, I; Márquez, L; Martínez, I; Molina-Torres, J; Prieto, S | 1 |
Cho, JY; Choi, JS; Hong, YK; Khan, MN; Lee, HH; Park, NG; Yoon, SJ | 1 |
Chang, IJ; Jeon, H; Kang, SM; Kim, SH; Kim, SY; Leem, KH; Lim, JP; Park, WH; Shin, HY; Shin, TY | 1 |
Goto, K; Kawata, K; Kitanaka, S; Yasukawa, K | 1 |
Bortolatto, CF; Jesse, CR; Nogueira, CW; Savegnago, L; Wilhelm, EA | 1 |
Dellinger, A; Kepley, CL; Lenk, R; MacFarland, D; Zhou, Z | 1 |
Asadullah, K; Becker, A; Buchmann, B; Döcke, WD; Friedrich, A; Gaestel, M; Grütz, G; Mengel, A; Naundorf, S; Röse, L; Schottelius, AJ; Zollner, TM; Zügel, U | 1 |
Fujimoto, Y; Iida, T; Yasukawa, K | 1 |
Elmets, CA; Katiyar, N; Katiyar, SK; Meeran, SM; Sharma, SD; Tisdale, GB; Xu, H; Yusuf, N | 1 |
Cho, HJ; Kim, JS; Lee, YM; Park, JH; Seon, MR | 1 |
Gaestel, M; Iversen, L; Johansen, C; Kollias, G; Kragballe, K; Vestergaard, C | 1 |
Benito, JM; Marco, FM; Marín-Alberca, G; Navarro-Blasco, FJ; Pérez-García, V; Peris-Pertusa, A; Sempere-Ortells, JM; Zubcoff, JJ | 1 |
Kim, DH; Kim, JK; Lim, H; Shin, EK; Shin, HK | 1 |
Ahmed, A; Ashcroft, M; Bloom, SL; Palmer, CD; Rahman, FZ; Segal, AW; Sewell, GW; Smith, AM | 1 |
Ghio, AJ; Madden, MC; Mundandhara, S; Sawyer, K | 1 |
Choe, J; Eom, S; Ha, KS; Hahn, JH; Jeoung, D; Kim, K; Kim, Y; Kim, YM; Lee, H; Lee, YS; Ro, JY | 1 |
Pasetka, C; Rubinchik, E | 1 |
Bennett, G; DeFuria, J; Greenberg, AS; Obin, MS; Shaul, ME; Strissel, KJ | 1 |
Chrysanthopoulou, A; Kambas, K; Kourtzelis, I; Mitroulis, I; Rafail, S; Ritis, K; Speletas, M | 1 |
Akhtar, N; Haqqi, TM; Khan, A; Khan, KA; Rasheed, Z | 1 |
Anesini, C; Casali, Y; Davicino, R; Mattar, A; Micalizzi, B | 1 |
Matsubara, H; Sano, Y; Yasukawa, K | 1 |
Cabrera, WH; Dragani, TA; Galvan, A; Ibañez, OM; Mancuso, M; Milani, S; Pazzaglia, S; Ribeiro, OG; Saran, A; Vorraro, F; Zolin, A | 1 |
Arnhold, J; Glander, HJ; Lessig, J; Neu, B; Reibetanz, U | 1 |
Andújar, I; Bacelli, T; Giner, RM; Recio, MC; Ríos, JL | 1 |
Jass, J; Khalaf, H; Olsson, PE | 1 |
Kim, EJ; Kim, J; Park, H; Park, JH | 1 |
Boulden, J; Chang, MY; DuHadaway, JB; Gilmour, SK; Mandik-Nayak, L; Muller, AJ; Prendergast, GC; Ramalingam, A; Soler, AP; Sutanto-Ward, E | 1 |
Kim, JA; Kim, SK; Kong, CS; Pyun, SY | 1 |
Daly, L; Maher, BM; Soo, AW; Watson, WR; Wood, AE | 1 |
Belotto, MF; Curi, R; Hatanaka, E; Magdalon, J; Pithon-Curi, TC; Rodrigues, HG; Vinolo, MA | 1 |
Angel, P; Bauer, T; Bierhaus, A; Brors, B; Busch, H; Eils, R; Gebhardt, C; Hess, J; König, R; Mark, R; Nawroth, P; Németh, J; Riehl, A | 1 |
Decicco-Skinner, KL; Lepage, PK; Simmons, JK; Trovato, EL; Wiest, JS | 1 |
Coste, I; Druillennec, S; Eychene, A; Hainaut, P; Hmitou, I; Kfoury, A; Le Corf, K; Lebecque, S; Renno, T | 1 |
Hestvik, AL; Holmøy, T; Høglund, RA; Maghazachi, AA | 1 |
Fenical, W; Flachsmann, F; Jacobs, RS; Moya, CE; Schellhaas, K | 1 |
Cafferata, EE; Galliano, SR; Mengoni, ES; Moreno, S; Pivetta, OH; Rigano, LA; Rodriguez-Puebla, ML; Vichera, G; Vojnov, AA | 1 |
Chen, L; Qin, Z; Wang, C; Xiao, M; Zhang, J | 1 |
Cheng, YW; Hsu, YY; Huang, CC; Shyur, LF; Yang, SD | 1 |
Cho, HJ; Kim, J; Kim, JS; Kim, SG; Lee, YM; Park, JH; Ponnuraj, SP | 1 |
Fabio, KM; Flowers, RA; Guillon, CD; Harman, MP; Heck, DE; Heindel, ND; Huang, MT; Laskin, JD; Saxena, J; Vetrano, AM; Young, SC | 1 |
Chung, WS; Kim, HL; Kim, SJ; Kim, SS; Shin, HJ; Um, JY | 1 |
Abarzua, F; Du, G; Huh, NH; Kataoka, K; Makino, T; Sakaguchi, M; Shimizu, T; Sonegawa, H; Than, SS | 1 |
Ikeuchi, H; Kinjo, T; Klinman, DM | 1 |
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Dong, M; Hirota, M; Iriye, R; Miyazaki, S; Nagaoka, M | 1 |
Cannady, SB; Combs, CK; Johnson, DE; Karlo, JC; Landreth, GE | 1 |
Ekekezie, II; Mabry, SM; Morgan, RE; Norberg, M; Rezaiekhaligh, MH; Thibeault, DW; Truog, WE; Zwick, DL | 1 |
Estess, P; Siegelman, MH; Stanescu, D | 1 |
Akihisa, T; Takido, M; Yasukawa, K; Yoshida, ZY | 1 |
Chan, C; Goldkorn, T | 1 |
Bridts, CH; De Clerck, LS; Mertens, AV; Moens, MM; Stevens, WJ | 1 |
Di Padova, F; Fearns, C; Gram, H; Han, J; Kline, L; Ulevitch, RJ; Zurini, M | 1 |
Daveau, M; Gueux, E; Lebreton, J; Linard, C; Malpuech-Brugère, C; Mazur, A; Nowacki, W; Rayssiguier, Y; Rock, E | 1 |
Everett, C; Gavrilova, O; Gonzalez, FJ; Hudson, LD; Lee, SS; Li, W; Peters, JM; Reitman, ML; Ward, JM | 1 |
Cerdá, M; De la Fuente, JR; Giner, RM; Máñez, S; Recio, MC; Ríos, JL; Uriburu, L | 1 |
Avis, IM; Cavanaugh, PF; Chen, Z; Hong, SH; Loukinova, E; Mulshine, JL; Ondrey, FG; Van Waes, C | 1 |
Finlay, T; Gerrets, R; Kadner, S; Krikun, G; Lockwood, CJ; Mesia, A; Schatz, F | 1 |
Lee, C; Liu, X; Miura, K; Zweier, JL | 1 |
Arosio, P; Dongiovanni, P; Fargion, S; Fiorelli, G; Fracanzani, AL; Levi, S; Mattioli, M; Scaccabarozzi, A; Valenti, L; Weiss, G | 1 |
Ishihara, N; Mori, H; Nakamura, Y; Nishidai, S; Ohigashi, H; Torikai, K; Yamamoto, M | 1 |
Garlington, S; Khavari, PA; Kirschberg, T; Kreider, E; Lin, Q; McGrane, PL; Rothbard, JB; Wender, PA | 1 |
Bosmann, M; Chang, JH; Hellmuth, M; Huwiler, A; Mühl, H; Ninic, R; Nold, M; Paulukat, J; Pfeilschifter, J | 1 |
Himmelfarb, J; McMonagle, E | 1 |
Herskovits, AT; Kristal, B; Nasser, L; Sela, S; Shapiro, G; Shasha, SM; Shurtz-Swirski, R | 1 |
Józwiak, J; Malejczyk, J; Skopiński, P | 1 |
Erjefält, JS; Malm-Erjefält, M; Persson, CG | 1 |
Kim, MP; Langenbach, R; Smart, RC; Tiano, HF; Wang, HQ | 1 |
Burger, D; Dayer, JM; Edwards, CK; Hyka, N; Kohno, T; Modoux, C; Roux-Lombard, P | 1 |
Nakamura, Y; Ohigashi, H; Torikai, K | 1 |
Grzela, T; Jozwiak, J; Malejczyk, J; Skopinski, P | 1 |
Jackson, SK; Jones, KP; Morris, RH; Price, AJ; Thomas, AW; Tonks, A | 1 |
Pashko, LL; Schwartz, AG | 1 |
Engelhardt, B; Hallmann, R; Pausch, F; Sixt, M; Sorokin, LM; Wendler, O | 1 |
Del Bigio, MR; Fotheringham, J; Geiger, JD; Mayne, M; Peeling, J; Power, C; Yan, HJ | 1 |
Balog, JM; Huff, GR; Huff, WE; Rath, NC; Xie, H | 1 |
Bird, CH; Bird, PI; Buzza, MS; Hirst, CE; Hosking, P; McKendrick, J | 1 |
Koningsberger, JC; Oldenburg, B; van Asbeck, BS; van Berge Henegouwen, GP; van Kats-Renaud, H | 1 |
Graf, M; Hirschelmann, R; Imming, P; Krause, E; Pawlitzki, G; Tries, S | 1 |
Bravo, A; Budunova, I; Del Río, M; Giménez-Conti, I; Jorcano, JL; Page, A; Pérez, P; Slaga, TJ | 1 |
Brelet, J; Courant, J; Duflos, M; Grimaud, N; LeBaut, G; Nourrisson, MR; Petit, JY | 1 |
Aumercier, M; Béchard, D; Dessaint, JP; Gentina, T; Hammad, H; Lassalle, P; Pestel, J; Scherpereel, A; Tonnel, AB; Tsicopoulos, A | 1 |
Azuma, Y; Ohura, K; Shinohara, M; Wang, PL | 1 |
Feng, Q; Kumagai, T; Nakamura, Y; Niki, E; Noguchi, N; Ohigashi, H; Osawa, T; Torikai, K; Uchida, K | 1 |
de las Heras, B; Fernández, MA; García, MD; Sáenz, MT; Villar, A | 1 |
Desvergne, B; Flühmann, B; Heim, M; Michalik, L; Noy, N; Pacot, C; Tan, NS; Wahli, W; Yasmin, R | 1 |
Czaja, MJ; Dannenberg, AJ; de Lédinghen, V; Liu, H; Lo, CR; Subbaramaiah, K; Zhang, F | 1 |
Kim, HW; Murakami, A; Nakamura, Y; Ohigashi, H | 1 |
Filler, RB; Geng, L; Girardi, M; Glusac, E; Hayday, AC; Lewis, J; Tigelaar, RE | 1 |
Cerdá-Nicolás, M; Giner, RM; Giner-Larza, EM; Máñez, S; Prieto, JM; Recio, MC; Ríos, JL | 1 |
Chen, J; Chen, NG; Forman, BM; Li, H; Stemerman, MB; Verna, L; Wang, N | 1 |
Brune, K; Hecker, E; Kalin, H; Schmidt, R | 1 |
Scribner, JD; Süss, R | 1 |
Evans, FJ; Schmidt, RJ | 1 |
Scribner, JD; Slaga, TJ; Viaje, A | 1 |
Kishikawa, K; Maruyama, T; Miyamoto, T; Seo, R; Tateishi, N; Toda, M | 1 |
Corrigall, V; Linardopoulos, S; Panayi, GS | 1 |
Galli, SJ; Geissler, EN; Tsai, M; Wershil, BK; Zsebo, KM | 1 |
Carroll, FI; Franson, RC; Lewin, AH; Nettleton, DO; Stanley, PL; Steiner, SA; Tramposch, KM | 1 |
Hibbs, MS | 1 |
Aburada, M; Ikeya, Y; Iwasaki, M; Mitsuhashi, H; Nakagawa, S; Takeuchi, M; Takido, M; Yasukawa, K | 1 |
Ameri, A; Bajaj, SP; Basu, S; Kuppuswamy, MN | 1 |
Cramer, R; Dri, P; Patriarca, P; Romano, M; Spessotto, P | 1 |
Nowak, D; Piasecka, G | 1 |
Amstutz, HC; Campbell, PA; Cracchiolo, A; Feng, D; Finerman, GA; Kilgus, DJ; Kossovsky, N; Liao, K; Millett, D; Thomas, BJ | 1 |
Brinckerhoff, CE; Coon, CI; Mitchell, TI | 1 |
Erickson, KL; Hubbard, NE; Somers, SD | 1 |
Hirota, M; Irie, R; Jisaka, M; Koshimizu, K; Murakami, A; Ohigashi, H | 1 |
Skisak, C | 1 |
Beecroft, WA; Brandes, LJ; Hogg, GR | 1 |
Ikekawa, T; Nakagawa, S; Shimada, F; Takeuchi, M; Takido, M; Yasukawa, K | 1 |
Bultmann, H; Glade, U; Häfker, T; Vicker, MG | 1 |
Djuric, SW; Fretland, DJ; Gaginella, TS; Levin, S; Shone, RL; Tsai, BS; Walsh, RE; Widomski, DL; Zemaitis, JM | 1 |
Coxson, HO; Doerschuk, CM; Harlan, JM; Winn, RK | 1 |
Nourshargh, S; Williams, TJ | 1 |
Hanawa, K; Kobayashi, S; Kurosawa, M; Nakano, M | 1 |
Brasier, AR; Habener, JF; Ron, D; Tate, JE; Wright, KA | 1 |
Fischer, SM; Patamalai, B; Patrick, KE; Slaga, TJ | 1 |
Blackham, A; Griffiths, RJ; Hallam, C; Mann, J; Mitchell, PD; Norris, AA; Simpson, WT | 1 |
Marathe, SA; Nair, X; Quigley, JW; Stanley, PL; Steiner, SA; Tramposch, KM; Zusi, FC | 1 |
Albertine, KH; Berd, D; Cerasoli, F; Gee, MH; Ishihara, Y; Peters, SP | 1 |
Cato, AC; Gebel, S; Herrlich, P; Jonat, C; Park, KK; Ponta, H; Rahmsdorf, HJ | 1 |
Camarero, VC; Colepicolo, P; Junqueira, VB; Karnovsky, ML; Mariano, M | 1 |
Brozna, JP; Carson, SD; Horan, M | 1 |
Bjerrum, OW; Borregaard, N; Nissen, MH | 1 |
Hartmann, HJ; Miesel, R; Weser, U | 1 |
Mahe, Y; Matsushima, K; Mukaida, N | 1 |
Aarsaether, N; Aarsland, A; Berge, RK; Fosse, R | 1 |
Blumberg, PM; Szallasi, A | 2 |
Eierman, DF; Haskill, S; Johnson, CE; Ladner, M; Martin, G; Morris, J; Sporn, SA | 1 |
Chofflon, M; González, V; Hafler, DA; Weiner, HL | 1 |
Calhoun, W; Carlson, RP; Chang, JY; Datko, L; Kreft, AF; Musser, JH; O'Neill-Davis, L | 1 |
Boutwell, RK | 1 |
Bassett, DJ; Esterline, RL; Trush, MA | 1 |
Aizu, E; Hosoda, Y; Kato, R; Kiyoto, I; Nakadate, T; Yamamoto, S | 1 |
Hayashi, I; Hayashi, M; Oh-ishi, S; Utsunomiya, I; Yamaki, K | 1 |
Nakagawa, S; Takeuchi, M; Takido, M; Yasukawa, K | 1 |
Eierman, DF; Haskill, JS; Johnson, CE | 1 |
Buckley, S; Grimes, D; Holloway, DA; Osborne, MC; Rimele, TJ; Sturm, RJ; Weichman, BM | 1 |
Albertine, KH; Gee, MH; Gottlieb, JE; Peters, SP | 1 |
Krakauer, T | 1 |
Kensler, TW; Seed, JL; Trush, MA | 1 |
Bohl, BP; Clancy, RM; Cochrane, CG; Halsey, WA; Revak, SD; Rice, CL; Schraufstätter, IU | 1 |
Lichtenstein, A | 1 |
DiMartino, MJ; Hanna, N; Johnson, WJ | 1 |
Kitagawa, S; Ohsaka, A; Saito, M; Takaku, F; Yuo, A | 1 |
Fujiki, H; Hayashi, Y; Hirasawa, N; Ohuchi, K; Sugimura, T; Takahashi, C; Tsurufuji, S; Watanabe, M | 1 |
Blazek, E; Carlson, RP; Chang, J | 1 |
Adams, DO; Lewis, JG | 2 |
Nitta, K; Takeuchi, M; Takido, M; Yasukawa, K | 1 |
Chouroulinkov, I; Giao, NB; Truhaut, R | 1 |
Elder, JT; Fisher, GJ; Gupta, AK; Voorhees, JJ | 1 |
Aronson, M; Berliner, S; Bruhis, S; Fishelson, Z; Kaufman, H; Pinhas, J | 1 |
Egner, PA; Kensler, TW; Moore, KG; Taffe, BG; Trush, MA; Twerdok, LE | 1 |
Hayashi, I; Hayashi, M; Nagashima, Y; Nakano, T; Oh-Ishi, S; Utsunomiya, I; Yamaki, K; Yamasu, A | 1 |
LaHann, TR | 1 |
DeHart, PD; Simon, RH; Todd, RF | 1 |
Clark, DA; Dessypris, EN; Koury, MJ | 1 |
Argyris, TS | 1 |
Kiyomiya, K; Oh-ishi, S | 1 |
11 review(s) available for tetradecanoylphorbol acetate and Innate Inflammatory Response
Article | Year |
---|---|
Models of acute inflammation in the ear.
Topics: Alkynes; Animals; Anthralin; Arachidonic Acid; Cantharidin; Capsaicin; Carrageenan; Croton Oil; Dermatitis; Disease Models, Animal; Diterpenes; Edema; Foot; Inflammation; Irritants; Male; Mice; Models, Animal; Mustard Plant; Otitis Externa; Plant Extracts; Plant Oils; Rats; Reproducibility of Results; Terpenes; Tetradecanoylphorbol Acetate; Zymosan | 2003 |
T-cell recruitment and specificity in allergic inflammation.
Topics: Allergens; Asthma; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Cells, Cultured; Chemotaxis, Leukocyte; Clone Cells; Flow Cytometry; Gene Expression Regulation; Gene Rearrangement, T-Lymphocyte; Humans; Hypersensitivity; Hypersensitivity, Immediate; Inflammation; Interferon-gamma; Interleukins; Ionomycin; Lymphocyte Activation; Phytohemagglutinins; Receptors, Antigen, T-Cell, alpha-beta; Staining and Labeling; T-Lymphocyte Subsets; Tetradecanoylphorbol Acetate | 2000 |
Role of cytokines in inflammatory process in Parkinson's disease.
Topics: Animals; Cytokines; Hippocampus; Humans; Inflammation; Microglia; Neostriatum; Parkinson Disease; Putamen; Substantia Nigra; Tetradecanoylphorbol Acetate | 2006 |
Role of toxic oxygen products from phagocytic cells in tissue injury.
Topics: Animals; Antigen-Antibody Complex; Arthus Reaction; Complement C5; Complement C5a; Free Radicals; Hydrogen Peroxide; Inflammation; Neutrophils; Oxygen; Phagocytosis; Rats; Superoxide Dismutase; Superoxides; Tetradecanoylphorbol Acetate | 1983 |
Poly-L-arginine and an N-formylated chemotactic peptide act synergistically with lectins and calcium ionophore to induce intense chemiluminescence and superoxide production in human blood leukocytes. Modulation by metabolic inhibitors, sugars, and polyele
Topics: Antimetabolites; Calcimycin; Carbohydrates; Cytochalasin B; Drug Synergism; Electrolytes; Histones; Humans; Inflammation; Lectins; Leukocytes; Ligands; Luminescent Measurements; Luminol; Lysophosphatidylcholines; N-Formylmethionine Leucyl-Phenylalanine; Peptides; Polymyxin B; Superoxides; Tetradecanoylphorbol Acetate | 1984 |
Manifestations of oxidant stress in uremia.
Topics: Biomarkers; Blood Proteins; C-Reactive Protein; Cardiovascular Diseases; Dose-Response Relationship, Drug; Elapid Venoms; Humans; Hypochlorous Acid; Inflammation; Kidney Failure, Chronic; Macrophage Activation; N-Formylmethionine Leucyl-Phenylalanine; Oxidation-Reduction; Oxidative Stress; Peroxidase; Phagocytes; Phagocytosis; Renal Dialysis; Sulfhydryl Compounds; Tetradecanoylphorbol Acetate; Uremia | 2001 |
Tumor initiation and promotion.
Topics: Animals; Carcinogens; Cocarcinogenesis; DNA Repair; Dose-Response Relationship, Drug; Growth Inhibitors; Humans; Hyperplasia; Inflammation; Models, Biological; Mutation; Neoplasms; Phorbols; Tetradecanoylphorbol Acetate | 1978 |
A structure-function approach to investigate the role of inflammatory cells and mediators in the production of acute lung injury.
Topics: Acute Disease; Animals; Humans; Inflammation; Leukotriene B4; Neutrophils; Respiratory Distress Syndrome; Sheep; SRS-A; Tetradecanoylphorbol Acetate; Vasoconstriction | 1988 |
Human interleukin 1.
Topics: Animals; B-Lymphocytes; Cell Line; Cloning, Molecular; Connective Tissue; Fever; Growth Substances; Humans; Inflammation; Interleukin-1; Interleukin-4; Leukemia, Myeloid; Lymphocyte Activation; Lymphokines; Macrophages; Mice; Monocytes; Monokines; Proteins; Receptors, Immunologic; Receptors, Interleukin-1; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1986 |
The respiratory burst of granulocytes: modulation by inflammatory mediators and its mechanism.
Topics: Animals; Calcium; Colony-Stimulating Factors; Granulocytes; Humans; In Vitro Techniques; Inflammation; Ionomycin; Membrane Potentials; N-Formylmethionine Leucyl-Phenylalanine; Oxygen; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1988 |
Regeneration and the mechanism of epidermal tumor promotion.
Topics: Acetates; Acetic Acid; Animals; Carcinogens; Cell Differentiation; Connective Tissue Cells; Diterpenes; Epidermal Cells; Humans; Hyperplasia; Inflammation; Models, Biological; Regeneration; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate; Time Factors | 1985 |
3 trial(s) available for tetradecanoylphorbol acetate and Innate Inflammatory Response
Article | Year |
---|---|
Effects of docosahexaenoic supplementation and in vitro vitamin C on the oxidative and inflammatory neutrophil response to activation.
Topics: Ascorbic Acid; Catalase; Dietary Supplements; Docosahexaenoic Acids; Erythrocytes; Gene Expression Regulation; Humans; Inflammation; Interleukin-6; Male; Neutrophil Activation; Neutrophils; Nitrates; Nitrites; Oxidative Stress; Peroxidase; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Young Adult | 2015 |
Preoperative neutrophil response as a predictive marker of clinical outcome following open heart surgery and the impact of leukocyte filtration.
Topics: Aged; CD11b Antigen; Coronary Artery Bypass; Female; Flow Cytometry; Heart Valve Prosthesis Implantation; Humans; Inflammation; L-Selectin; Leukapheresis; Leukocyte Count; Lipopolysaccharides; Male; Membrane Glycoproteins; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Preoperative Period; Tetradecanoylphorbol Acetate; Treatment Outcome | 2010 |
R406, an orally available spleen tyrosine kinase inhibitor blocks fc receptor signaling and reduces immune complex-mediated inflammation.
Topics: Animals; Antigen-Antibody Complex; Arthritis, Experimental; Arthus Reaction; B-Lymphocytes; Basophils; Blotting, Western; Cells, Cultured; Crystallography; Double-Blind Method; Enzyme Inhibitors; Fluorescence Polarization Immunoassay; Humans; Immunoglobulin G; Inflammation; Lipopolysaccharides; Macrophages; Mast Cells; Mice; Mice, Inbred BALB C; Oxazines; Platelet Aggregation; Protein-Tyrosine Kinases; Pyridines; Receptors, Fc; Signal Transduction; Spleen; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 2006 |
527 other study(ies) available for tetradecanoylphorbol acetate and Innate Inflammatory Response
Article | Year |
---|---|
Use of Cytokine Mix-, Imiquimod-, and Serum-Induced Monoculture and Lipopolysaccharide- and Interferon Gamma-Treated Co-Culture to Establish In Vitro Psoriasis-like Inflammation Models.
Topics: Adult; Cells, Cultured; Coculture Techniques; Cytokines; Gene Expression Profiling; Gene Expression Regulation; Genetic Markers; HaCaT Cells; Humans; Imiquimod; Inflammation; Interferon-gamma; Keratinocytes; Lipopolysaccharides; Models, Biological; Psoriasis; RNA, Messenger; Serum; Tetradecanoylphorbol Acetate | 2021 |
In Vitro and Clinical Evaluation of Cannabigerol (CBG) Produced via Yeast Biosynthesis: A Cannabinoid with a Broad Range of Anti-Inflammatory and Skin Health-Boosting Properties.
Topics: Anti-Inflammatory Agents; Antioxidants; Cannabidiol; Cannabinoids; Cells, Cultured; Dermatitis, Contact; Dermatologic Agents; Female; Gene Expression Regulation; Healthy Volunteers; Humans; Inflammation; Male; Models, Biological; Propionibacteriaceae; Saccharomyces cerevisiae; Skin; Skin Aging; Skin Irritancy Tests; Sodium Dodecyl Sulfate; Tetradecanoylphorbol Acetate; Tissue Array Analysis; Ultraviolet Rays | 2022 |
Aberrant HO-1/NQO1-Reactive Oxygen Species-ERK Signaling Pathway Contributes to Aggravation of TPA-Induced Irritant Contact Dermatitis in Nrf2-Deficient Mice.
Topics: Animals; Dermatitis, Contact; Fibroblasts; Heme Oxygenase-1; Inflammation; Irritants; Mice; Mice, Knockout; NF-E2-Related Factor 2; Reactive Oxygen Species; Signal Transduction; Tetradecanoylphorbol Acetate | 2022 |
Interactions between the Nociceptin and Toll-like Receptor Systems.
Topics: Humans; Inflammation; Lipopolysaccharides; Nociceptin; Opioid Peptides; RNA, Messenger; Tetradecanoylphorbol Acetate; Toll-Like Receptor 2; Toll-Like Receptor 4; Toll-Like Receptor 7; Toll-Like Receptor 9; Toll-Like Receptors | 2022 |
Responses of promyelocytic leukemia HL60 cells as an inflammatory cell lineage model to silica microparticles used to coat blood collection tubes.
Topics: Animals; Cell Lineage; Dimethyl Sulfoxide; HL-60 Cells; Humans; Inflammation; Leukemia, Promyelocytic, Acute; Mice; Plastics; Silicon Dioxide; Superoxide Dismutase; Tetradecanoylphorbol Acetate | 2022 |
TIPE2 May Target the Nrf2/HO-1 Pathway to Inhibit M1 Macrophage-Related Neutrophilic Inflammation in Asthma.
Topics: Asthma; Heme Oxygenase-1; Humans; Inflammation; Intracellular Signaling Peptides and Proteins; Lipopolysaccharides; Macrophages; NF-E2-Related Factor 2; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2022 |
Immunomodulatory effects of chicken cathelicidin-2 on a primary hepatic cell co-culture model.
Topics: Adenosine Monophosphate; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antimicrobial Cationic Peptides; Cathelicidins; Chickens; Coculture Techniques; Hepatocytes; Hydrogen Peroxide; Immunity; Inflammation; Interferon-gamma; Interleukin-10; Lactate Dehydrogenases; Liver; Macrophage Colony-Stimulating Factor; Malondialdehyde; Pathogen-Associated Molecular Pattern Molecules; Reactive Oxygen Species; Tetradecanoylphorbol Acetate | 2022 |
Keratinocyte Regnase-1, a Downregulator of Skin Inflammation, Contributes to Protection against Tumor Promotion by Limiting Cyclooxygenase-2 Expression.
Topics: Acetates; Animals; Carcinogenesis; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cyclooxygenase 2; Dermatitis; Humans; Inflammation; Keratinocytes; Lithostathine; Mice; RNA, Messenger; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2023 |
Alkaloids Extract from
Topics: Acetates; Alkaloids; Animals; Anti-Inflammatory Agents; Antioxidants; Edema; Flax; Inflammation; Mice; Oxidative Stress; Plant Extracts; Tetradecanoylphorbol Acetate | 2023 |
Irisin inhibits neutrophil extracellular traps formation and protects against acute pancreatitis in mice.
Topics: Acute Disease; Animals; Extracellular Traps; Fibronectins; Inflammation; Mice; Neutrophils; Pancreatitis; Tetradecanoylphorbol Acetate | 2023 |
Anti-proliferative and anti-inflammatory effects of the application of baclofen cream, a GABA
Topics: Animals; Anti-Inflammatory Agents; Baclofen; Dermatitis; Dexamethasone; Edema; GABA-B Receptor Agonists; Inflammation; Mice; Skin Diseases; Tetradecanoylphorbol Acetate | 2023 |
Opposing roles of endothelial and leukocyte-expressed IL-7Rα in the regulation of psoriasis-like skin inflammation.
Topics: Animals; Antibodies, Neutralizing; CD4-Positive T-Lymphocytes; Disease Models, Animal; Endothelial Cells; Female; Gene Expression Regulation; Humans; Imiquimod; Inflammation; Interleukin-7; Lymph Nodes; Lymphatic Vessels; Male; Mice; Mice, Inbred C57BL; Organ Specificity; Oxazolone; Psoriasis; Receptors, Interleukin-7; Signal Transduction; Skin; Tetradecanoylphorbol Acetate | 2019 |
Comparison of anti-inflammatory mechanisms between doxofylline and theophylline in human monocytes.
Topics: Anti-Inflammatory Agents; Humans; Inflammation; Lipopolysaccharides; Monocytes; Protein Kinase C; Tetradecanoylphorbol Acetate; Theophylline | 2019 |
The transmembrane protein LRIG2 increases tumor progression in skin carcinogenesis.
Topics: Aged; Aged, 80 and over; Animals; Carcinogenesis; Cell Differentiation; Cell Line, Tumor; Disease Progression; Epidermis; ErbB Receptors; Homeostasis; Humans; Hyperplasia; Inflammation; Membrane Glycoproteins; Mice, Inbred C57BL; Phenotype; Protein Binding; Skin Neoplasms; Tetradecanoylphorbol Acetate; Thrombospondins | 2019 |
Pericytes enable effective angiogenesis in the presence of proinflammatory signals.
Topics: Cell Communication; Cell Culture Techniques; Coculture Techniques; Dose-Response Relationship, Drug; Endothelial Cells; Fibroblast Growth Factor 2; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Lysophospholipids; Models, Biological; Neovascularization, Pathologic; Neovascularization, Physiologic; Pericytes; Receptors, Notch; Signal Transduction; Sphingosine; Tetradecanoylphorbol Acetate; Tissue Engineering; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A | 2019 |
Transduced Tat-CIAPIN1 reduces the inflammatory response on LPS- and TPA-induced damages.
Topics: Animals; Apoptosis; Cyclooxygenase 2; Disease Models, Animal; Edema; Inflammation; Interleukin-6; Intracellular Signaling Peptides and Proteins; Lipopolysaccharides; Male; Mice; Mice, Inbred ICR; Mitogen-Activated Protein Kinases; NF-kappa B; Nitric Oxide Synthase Type II; RAW 264.7 Cells; Reactive Oxygen Species; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2019 |
PEP-1-GLRX1 protein exhibits anti-inflammatory effects by inhibiting the activation of MAPK and NF-κB pathways in Raw 264.7 cells.
Topics: Animals; Anti-Inflammatory Agents; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cysteamine; Edema; Glutaredoxins; Inflammation; Lipopolysaccharides; Male; Mice; Mice, Inbred ICR; Mitogen-Activated Protein Kinases; NF-kappa B; Nitric Oxide Synthase Type II; Peptides; Phosphorylation; RAW 264.7 Cells; Signal Transduction; Tetradecanoylphorbol Acetate | 2020 |
Super Critical Fluid Extracted Fatty Acids from
Topics: Animals; Disease Models, Animal; Humans; Inflammation; Interleukin-6; Mice; Psoriasis; RAW 264.7 Cells; Seeds; Signal Transduction; Skin; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Withania | 2020 |
Enhancement of the cancer inhibitory effect of the bioactive food component resveratrol by nanoparticle based delivery.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Apoptosis; Biological Availability; Carcinogenesis; Inflammation; Mice; Nanoparticles; Oxidative Stress; Phytochemicals; Resveratrol; Skin; Tetradecanoylphorbol Acetate | 2020 |
Topics: Active Transport, Cell Nucleus; Caspase 1; Cell Nucleus; Cytoplasm; Escherichia coli; Escherichia coli Proteins; Gene Expression Regulation; Host-Pathogen Interactions; Humans; Inflammation; Interleukin-12; Interleukin-1beta; MAP Kinase Kinase 4; Microbial Viability; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phagocytosis; Signal Transduction; Tetradecanoylphorbol Acetate; THP-1 Cells; Tumor Necrosis Factor-alpha | 2020 |
Significance of neutrophil microparticles in ischaemia-reperfusion: Pro-inflammatory effectors of endothelial senescence and vascular dysfunction.
Topics: Angiotensins; Animals; Apoptosis; Blood Coagulation; Cell Lineage; Cell-Derived Microparticles; Cellular Senescence; Cyclooxygenase 2; Endothelial Cells; Endothelium, Vascular; Inflammation; Lipopolysaccharides; Male; MAP Kinase Signaling System; Monocytes; Neutrophils; NF-kappa B; Oxidative Stress; Phosphatidylinositol 3-Kinases; Phosphorylation; Rats, Wistar; Reperfusion Injury; Spleen; Swine; Tetradecanoylphorbol Acetate; Thromboplastin; Vascular Cell Adhesion Molecule-1 | 2020 |
Lymphocyte activation after a high-intensity street dance class.
Topics: Creatine Kinase, MB Form; Dancing; Heart Rate; Humans; Inflammation; L-Selectin; Lymphocyte Activation; Lymphocyte Count; Male; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Young Adult | 2020 |
Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Cytokines; Female; Inflammation; Mice; Peptidomimetics; Tetradecanoylphorbol Acetate | 2020 |
Phorbol 12-Myristate 13-Acetate Induced Toxicity Study and the Role of Tangeretin in Abrogating HIF-1α-NF-κB Crosstalk In Vitro and In Vivo.
Topics: Animals; Antioxidants; Biomarkers; Cell Line, Transformed; Congenital Abnormalities; Embryonic Development; Epidermis; Flavones; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammation; Keratinocytes; Lipid Peroxidation; NF-kappa B; Onions; Oxidative Stress; Reactive Oxygen Species; Signal Transduction; Tetradecanoylphorbol Acetate; Zebrafish | 2020 |
Effect of Baricitinib on TPA-induced psoriasis like skin inflammation.
Topics: Administration, Topical; Animals; Azetidines; Carcinogens; Inflammation; Mice; Mice, Inbred BALB C; Psoriasis; Purines; Pyrazoles; Skin; Sulfonamides; Tetradecanoylphorbol Acetate | 2021 |
Flavonoids and saponins from Passiflora edulis f. edulis leaves (purple passion fruit) and its potential anti-inflammatory activity.
Topics: Animals; Anti-Inflammatory Agents; Chromatography, High Pressure Liquid; Female; Flavonoids; Inflammation; Mice, Inbred ICR; Nitric Oxide Synthase; Passiflora; Phytotherapy; Plant Extracts; Plant Leaves; Saponins; Skin; Skin Diseases; Tandem Mass Spectrometry; Tetradecanoylphorbol Acetate | 2021 |
Neutrophil extracellular traps can serve as platforms for processing and activation of IL-1 family cytokines.
Topics: Cathepsin G; Cytoplasmic Granules; Deoxyribonuclease I; Extracellular Traps; Humans; Inflammation; Interleukin-1; Interleukin-1alpha; Leukocyte Elastase; Myeloblastin; Neutrophil Activation; Recombinant Proteins; Tetradecanoylphorbol Acetate | 2017 |
PAD2 overexpression in transgenic mice augments malignancy and tumor-associated inflammation in chemically initiated skin tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogenesis; Carcinogens; Disease Progression; Gene Expression Regulation, Neoplastic; Humans; Inflammation; Male; Mice; Mice, Transgenic; Papilloma; Protein-Arginine Deiminase Type 2; Protein-Arginine Deiminases; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Up-Regulation | 2017 |
The Role of Fibroblast Growth Factor-Binding Protein 1 in Skin Carcinogenesis and Inflammation.
Topics: Animals; Bone Marrow; Bone Marrow Transplantation; Carcinogenesis; Carcinogens; Carrier Proteins; Female; Humans; Inflammation; Intercellular Signaling Peptides and Proteins; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neoplasms, Experimental; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Up-Regulation; Water Loss, Insensible; Wound Healing | 2018 |
Mechanisms of the Innate Defense Regulator Peptide-1002 Anti-Inflammatory Activity in a Sterile Inflammation Mouse Model.
Topics: Animals; Anti-Inflammatory Agents; Antimicrobial Cationic Peptides; Disease Models, Animal; Ear; Female; Humans; Immunity, Innate; Inflammation; Interferon-gamma; Lipopolysaccharides; Mice; Mice, Inbred Strains; RAW 264.7 Cells; Teichoic Acids; Tetradecanoylphorbol Acetate; Toll-Like Receptor 2; Toll-Like Receptor 4 | 2017 |
Fidaxomicin and OP-1118 Inhibit Clostridium difficile Toxin A- and B-Mediated Inflammatory Responses via Inhibition of NF-κB Activity.
Topics: Aminoglycosides; Animals; Apoptosis; Bacterial Proteins; Bacterial Toxins; Cell Line; Clostridioides difficile; Enterotoxins; Epithelial Cells; Fidaxomicin; Humans; Inflammation; Interleukin-1beta; Intestinal Mucosa; Mice; NF-kappa B; Phosphorylation; RAW 264.7 Cells; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2018 |
Rapamycin inhibits ox-LDL-induced inflammation in human endothelial cells in vitro by inhibiting the mTORC2/PKC/c-Fos pathway.
Topics: Cell Adhesion; Cells, Cultured; Dose-Response Relationship, Drug; E-Selectin; Gene Knockdown Techniques; Genes, fos; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Intercellular Adhesion Molecule-1; Lipoproteins, LDL; Mechanistic Target of Rapamycin Complex 2; Protein Kinase C; Rapamycin-Insensitive Companion of mTOR Protein; Regulatory-Associated Protein of mTOR; RNA, Small Interfering; Signal Transduction; Sirolimus; Staurosporine; Tetradecanoylphorbol Acetate | 2018 |
MAPKs and NF‑κB pathway inhibitory effect of bisdemethoxycurcumin on phorbol‑12‑myristate‑13‑acetate and A23187‑induced inflammation in human mast cells.
Topics: Calcimycin; Cell Line; Curcumin; Diarylheptanoids; Gene Expression Regulation; Humans; Inflammation; Mast Cells; Mitogen-Activated Protein Kinase Kinases; NF-kappa B; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factor RelA | 2018 |
Interaction of factor VII activating protease (FSAP) with neutrophil extracellular traps (NETs).
Topics: Coronary Thrombosis; Deoxyribonucleases; Extracellular Traps; Factor VII; Histones; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Neutrophils; Nucleosomes; Serine Endopeptidases; Tetradecanoylphorbol Acetate; Thrombosis | 2018 |
Effect of tannic acid on skin barrier function.
Topics: Animals; Dermatitis, Contact; Disease Models, Animal; Epidermis; Fluorescent Dyes; Inflammation; Isoquinolines; Male; Mice; Mice, Inbred ICR; Permeability; Skin; Skin Diseases; Sweat; Tannins; Tetradecanoylphorbol Acetate | 2018 |
Ingenol-3-Angelate Suppresses Growth of Melanoma Cells and Skin Tumor Development by Downregulation of NF-κB-Cox2 Signaling.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Apoptosis Regulatory Proteins; Carcinogenesis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclooxygenase 2; Diterpenes; Down-Regulation; Epidermis; Female; Hyperplasia; Inflammation; Melanoma; Mice, Inbred ICR; NF-kappa B; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2018 |
(E)-2-Methoxy-4-(3-(4-methoxyphenyl) prop-1-en-1-yl) phenol attenuates PMA-induced inflammatory responses in human monocytic cells through PKCδ/JNK/AP-1 pathways.
Topics: Anti-Inflammatory Agents; Cell Line; Cyclooxygenase 2; Down-Regulation; Humans; Inflammation; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Monocytes; Phosphorylcholine; Phthalic Acids; Polymethacrylic Acids; Protein Kinase C-delta; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factor AP-1 | 2018 |
A pivotal role for NF-κB in the macrophage inflammatory response to the myeloperoxidase oxidant hypothiocyanous acid.
Topics: Atherosclerosis; Cell Differentiation; Cell Line; Cell Survival; Chemokines; Cytokines; Humans; Inflammation; Inflammation Mediators; Macrophages; NF-kappa B; Peroxidase; Smoking; Sulfhydryl Compounds; Tetradecanoylphorbol Acetate; Thiocyanates; Up-Regulation | 2018 |
Cysteine ameliorates allergic inflammatory reactions by suppressing thymic stromal lymphopoietin production in activated human mast cells.
Topics: Calcium Ionophores; Caspase 1; Cell Line; Cysteine; Cytokines; Humans; Hypersensitivity; Inflammation; JNK Mitogen-Activated Protein Kinases; Mast Cells; NF-kappa B; Phosphorylation; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Thymic Stromal Lymphopoietin | 2018 |
Early age exposure to moisture damage and systemic inflammation at the age of 6 years.
Topics: Air Pollutants; Air Pollution, Indoor; C-Reactive Protein; Child; Cytokines; Environmental Exposure; Female; Fungi; Humans; Infant; Inflammation; Interleukin-1beta; Interleukin-6; Ionomycin; Leukocyte Count; Leukocytes; Lipopolysaccharides; Male; Peptidoglycan; Prospective Studies; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2018 |
Co-culture of human bone marrow mesenchymal stem cells and macrophages attenuates lipopolysaccharide-induced inflammation in human corneal epithelial cells.
Topics: Animals; Bone Marrow Cells; Cell Differentiation; Cells, Cultured; Chromatography, Gel; Coculture Techniques; Culture Media, Conditioned; Epithelium, Corneal; Humans; Inflammation; Interleukin 1 Receptor Antagonist Protein; Interleukin-1beta; Lipopolysaccharides; Macrophages; Mesenchymal Stem Cells; Mice; Mice, Inbred BALB C; Tandem Mass Spectrometry; Tetradecanoylphorbol Acetate; Wound Healing | 2018 |
Topical delivery of l-theanine ameliorates TPA-induced acute skin inflammation via downregulating endothelial PECAM-1 and neutrophil infiltration and activation.
Topics: Administration, Topical; Animals; Cell Proliferation; Cyclooxygenase 2; Down-Regulation; Ear; Edema; Female; Glutamates; Inflammation; Interleukin-1beta; Mice; Neutrophil Infiltration; Neutrophils; Permeability; Platelet Endothelial Cell Adhesion Molecule-1; Skin; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2018 |
GABA and GABA-Alanine from the Red Microalgae Rhodosorus marinus Exhibit a Significant Neuro-Soothing Activity through Inhibition of Neuro-Inflammation Mediators and Positive Regulation of TRPV1-Related Skin Sensitization.
Topics: Alanine; Cells, Cultured; gamma-Aminobutyric Acid; Humans; Inflammation; Inflammation Mediators; Interleukin-1alpha; Keratinocytes; Microalgae; Nerve Growth Factor; Neurons; Receptor, Nerve Growth Factor; Skin; Tetradecanoylphorbol Acetate; TRPV Cation Channels | 2018 |
Novel dual-targeting anti-proliferative dihydrotriazine-chalcone derivatives display suppression of cancer cell invasion and inflammation by inhibiting the NF-κB signaling pathway.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Chalcone; Cyclooxygenase 2; Down-Regulation; Enzyme-Linked Immunosorbent Assay; Humans; Inflammation; Inflammation Mediators; Lipopolysaccharides; Matrix Metalloproteinase 9; Mice; Monocytes; Neoplasm Invasiveness; NF-kappa B; Nitric Oxide Synthase Type II; RAW 264.7 Cells; Signal Transduction; Tetradecanoylphorbol Acetate; Triazines | 2018 |
Soy Phosphatidylglycerol Reduces Inflammation in a Contact Irritant Ear Edema Mouse Model In Vivo.
Topics: Animals; Disease Models, Animal; Edema; Glycine max; Inflammation; Irritants; Keratinocytes; Male; Mice; Phosphatidylglycerols; Tetradecanoylphorbol Acetate | 2018 |
MiR-302e attenuates allergic inflammation
Topics: Calcimycin; Cell Line; Gene Expression Regulation; Humans; Inflammation; Mast Cells; MicroRNAs; NF-kappa B; Ovalbumin; Rhinitis, Allergic; Tetradecanoylphorbol Acetate; Transcription Factor RelA | 2018 |
Anti-allergic inflammatory components from Sanguisorba officinalis L.
Topics: Animals; Anti-Allergic Agents; beta-N-Acetylhexosaminidases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Inflammation; Interleukin-4; Lipopolysaccharides; Macrophages; Mice; Molecular Structure; Nitric Oxide; Rats; RAW 264.7 Cells; Sanguisorba; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2018 |
Chronotherapy of maxacalcitol on skin inflammation induced by topical 12-O-tetradecanoylphorbol-13-acetate in mice.
Topics: Animals; Calcitriol; Chronotherapy; Circadian Rhythm; Inflammation; Male; Mice; Mice, Inbred C57BL; Psoriasis; Receptors, Calcitriol; Skin; Tetradecanoylphorbol Acetate | 2018 |
Epidermal glucocorticoid and mineralocorticoid receptors act cooperatively to regulate epidermal development and counteract skin inflammation.
Topics: Animals; Cell Differentiation; Cell Proliferation; Epidermis; Gene Expression Regulation; Glucocorticoids; Imiquimod; Inflammation; Keratinocytes; Mice, Knockout; NF-kappa B; Phenotype; Phosphorylation; Psoriasis; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Signal Transduction; Tetradecanoylphorbol Acetate | 2018 |
Tuning the endothelial response: differential release of exocytic cargos from Weibel-Palade bodies.
Topics: 1-Methyl-3-isobutylxanthine; Actomyosin; Cytochalasins; Endothelial Cells; Epinephrine; Exocytosis; Hemostasis; Heterocyclic Compounds, 4 or More Rings; Histamine; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Leukocyte Rolling; P-Selectin; Protein Conformation; RNA Interference; RNA, Small Interfering; Tetradecanoylphorbol Acetate; von Willebrand Factor; Weibel-Palade Bodies | 2018 |
Red light-emitting diode irradiation regulates oxidative stress and inflammation through SPHK1/NF-κB activation in human keratinocytes.
Topics: Adaptor Proteins, Signal Transducing; Cell Line; Cell Survival; Cytokines; Down-Regulation; Heme Oxygenase-1; Humans; Immunohistochemistry; Inflammation; Keratinocytes; Light; Microscopy, Fluorescence; NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress; Reactive Oxygen Species; RNA Interference; RNA, Small Interfering; Tetradecanoylphorbol Acetate; Up-Regulation | 2018 |
PEP-1-PEA15 suppresses inflammatory responses by regulation of MAPK in macrophages and animal models.
Topics: Animals; Apoptosis Regulatory Proteins; Cysteamine; Cytokines; Disease Models, Animal; DNA Fragmentation; Edema; Extracellular Signal-Regulated MAP Kinases; Humans; Inflammation; Inflammation Mediators; Intracellular Signaling Peptides and Proteins; Lipopolysaccharides; Macrophages; Male; Mice; Mice, Inbred ICR; Peptides; Phosphoproteins; RAW 264.7 Cells; Reactive Oxygen Species; Signal Transduction; Tetradecanoylphorbol Acetate | 2018 |
Dibutyl phthalate modulates phenotype of granulocytes in human blood in response to inflammatory stimuli.
Topics: Adult; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; CD24 Antigen; Cytokines; Dibutyl Phthalate; Granulocytes; Humans; Immunity, Humoral; Immunity, Innate; In Vitro Techniques; Inflammation; Lectins, C-Type; Lipopolysaccharides; Membrane Proteins; Middle Aged; Neutrophils; Plasticizers; Receptors, IgG; Tetradecanoylphorbol Acetate; Young Adult | 2018 |
AT2R Activation Prevents Microglia Pro-inflammatory Activation in a NOX-Dependent Manner: Inhibition of PKC Activation and p47
Topics: Angiotensin II; Animals; Cell Line; Glycogen Synthase Kinase 3 beta; Inflammation; Lipopolysaccharides; Mice; Microglia; Mitochondria; NADPH Oxidases; Neurons; NF-E2-Related Factor 2; Oxidative Stress; Phosphorylation; Protein Kinase C; Protein Phosphatase 2; Proteolysis; Reactive Oxygen Species; Receptor, Angiotensin, Type 2; Tetradecanoylphorbol Acetate | 2019 |
Abnormally expressed miR-23b in Chinese Mongolian at high cardiovascular risk may contribute to monocyte/macrophage inflammatory reaction in atherosclerosis.
Topics: Atherosclerosis; Cardiovascular Diseases; Cell Differentiation; Cell Line; China; Female; Gene Expression Regulation, Neoplastic; Healthy Volunteers; Humans; Inflammation; Leukocytes, Mononuclear; Lipoproteins, LDL; Macrophages; Male; MicroRNAs; Middle Aged; NF-kappa B; Risk Factors; Signal Transduction; Tetradecanoylphorbol Acetate | 2018 |
Comparison of the anti-inflammatory effects of Sinapis alba and Brassica juncea in mouse models of inflammation.
Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acid; China; Edema; Inflammation; Interleukin-1beta; Interleukin-6; Male; Mice; Mice, Inbred BALB C; Mustard Plant; Peroxidase; Plant Extracts; Seeds; Sinapis; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2018 |
Therapeutic potential of topically administered γ-AlOOH on 2,4-dinitrochlorobenzene-induced atopic dermatitis-like lesions in Balb/c mice.
Topics: Administration, Topical; Aluminum Hydroxide; Aluminum Oxide; Animals; Anti-Inflammatory Agents; Cell Line, Tumor; Cell Survival; Dermatitis, Atopic; Dinitrochlorobenzene; Epidermis; Humans; Inflammation; Interleukin-33; Interleukins; Keratinocytes; Mast Cells; Mice; Mice, Inbred BALB C; Oxidative Stress; Serine Endopeptidases; Skin; Skin Diseases; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2019 |
hsa-miR-20a-5p attenuates allergic inflammation in HMC-1 cells by targeting HDAC4.
Topics: Base Sequence; Calcimycin; Cell Line; Cytokines; Down-Regulation; Epigenesis, Genetic; Histone Deacetylases; Humans; Hypersensitivity; Inflammation; Inflammation Mediators; MicroRNAs; Ovalbumin; Repressor Proteins; Tetradecanoylphorbol Acetate | 2019 |
Immunomodulation of Zerumbone via Decreasing the Production of Reactive Oxygen Species from Immune Cells.
Topics: Animals; Dose-Response Relationship, Drug; Enzyme Precursors; Humans; Immune System; Immunomodulation; Inflammation; Inhibitory Concentration 50; Luminescence; Macrophages; Mice; Neutrophils; Plant Preparations; Reactive Oxygen Species; Respiratory Burst; Sesquiterpenes; Tetradecanoylphorbol Acetate | 2018 |
XB130 deficiency enhances carcinogen-induced skin tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adaptor Proteins, Signal Transducing; Animals; Carcinogenesis; Carcinogens; Cell Proliferation; Female; Genes, Tumor Suppressor; Inflammation; Male; Mice; Mice, Knockout; Microfilament Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2019 |
Synthesis and identification of quinoline derivatives as topoisomerase I inhibitors with potent antipsoriasis activity in an animal model.
Topics: Animals; Anti-Inflammatory Agents; Cytokines; Ear; Imiquimod; Inflammation; Male; Mice, Inbred BALB C; Psoriasis; Quinolines; Skin; Tetradecanoylphorbol Acetate; Topoisomerase I Inhibitors | 2019 |
Inhibitory effects of 7,7'-bromo-curcumin on 12-O-tetradecanoylphorbol-13-acetate-induced skin inflammation.
Topics: Animals; Curcumin; Cytokines; Edema; Inflammation; Male; Mice; NF-kappa B; Signal Transduction; Skin; STAT3 Transcription Factor; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 2019 |
The macrophage-related biomarkers sCD163 and sCD206 are released by different shedding mechanisms.
Topics: Antigens, CD; Antigens, Differentiation, Myelomonocytic; Biomarkers; Humans; Inflammation; Lectins, C-Type; Lipopolysaccharides; Macrophages; Mannose Receptor; Mannose-Binding Lectins; Receptors, Cell Surface; Tetradecanoylphorbol Acetate; Zymosan | 2019 |
MiR-181a regulates inflammation responses in monocytes and macrophages.
Topics: 3' Untranslated Regions; Animals; Base Sequence; Binding Sites; Cell Line, Tumor; Gene Expression Regulation; Humans; Inflammation; Interleukin-1alpha; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Macrophages; Mice; MicroRNAs; Monocytes; Reactive Oxygen Species; RNA, Messenger; RNA, Small Interfering; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2013 |
[6]-Shogaol inhibits the production of proinflammatory cytokines via regulation of NF-κB and phosphorylation of JNK in HMC-1 cells.
Topics: Animals; Calcimycin; Calcium Ionophores; Carcinogens; Catechols; Cell Line; Cytokines; Histamine Release; Humans; Inflammation; Male; MAP Kinase Kinase 4; Mast Cells; Mutagens; NF-kappa B; Phosphorylation; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 2013 |
Neutrophil-mediated oxidation of erythrocyte peroxiredoxin 2 as a potential marker of oxidative stress in inflammation.
Topics: Animals; Biomarkers; Blotting, Western; Cells, Cultured; Endotoxemia; Erythrocytes; Humans; Hydrogen Peroxide; Hydrogen-Ion Concentration; Inflammation; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidases; Neutrophils; Oxidants; Oxidation-Reduction; Oxidative Stress; Peroxiredoxins; Respiratory Burst; Temperature; Tetradecanoylphorbol Acetate | 2013 |
Resolution of PMA-induced skin inflammation involves interaction of IFN-γ and ALOX15.
Topics: Animals; Arachidonate 12-Lipoxygenase; Arachidonate 15-Lipoxygenase; Female; Fluorescent Antibody Technique; Inflammation; Interferon-gamma; Lipoxins; Male; Mice; Real-Time Polymerase Chain Reaction; Skin; Tetradecanoylphorbol Acetate | 2013 |
Reactive oxygen species in peripheral blood and sputum neutrophils during bacterial and nonbacterial acute exacerbation of chronic obstructive pulmonary disease.
Topics: Aged; Anemia, Refractory, with Excess of Blasts; Female; Humans; Inflammation; Interleukin-8; Male; Middle Aged; Neutrophils; Oxidative Stress; Pulmonary Disease, Chronic Obstructive; Reactive Oxygen Species; Respiratory Burst; Respiratory Function Tests; Smoking; Sputum; Staphylococcus aureus; Tetradecanoylphorbol Acetate | 2013 |
Local and systemic neutrophilic inflammation in patients with lung cancer and chronic obstructive pulmonary disease.
Topics: Aged; Bronchoalveolar Lavage Fluid; Case-Control Studies; Cell Count; Female; Humans; Inflammation; Leukocyte Elastase; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Neutrophils; Peroxidase; Pulmonary Disease, Chronic Obstructive; Reactive Oxygen Species; Tetradecanoylphorbol Acetate | 2013 |
The preventive role of breadfruit against inflammation-associated epithelial carcinogenesis in mice.
Topics: Animals; Anticarcinogenic Agents; Artocarpus; Cyclooxygenase 2; Disease Models, Animal; Epithelial Cells; Female; Inflammation; Mice; Mice, Inbred ICR; Neoplasms, Experimental; Plant Extracts; Tetradecanoylphorbol Acetate | 2014 |
Neuroprotection effect of interleukin (IL)-17 secreted by reactive astrocytes is emerged from a high-level IL-17-containing environment during acute neuroinflammation.
Topics: Animals; Antibodies, Blocking; Apoptosis; Astrocytes; Autoimmunity; Inflammation; Interferon-gamma; Interleukin-17; Janus Kinases; Leukocytes, Mononuclear; Neurons; Rats; Rats, Inbred Lew; Rats, Wistar; RNA, Messenger; STAT Transcription Factors; Tetradecanoylphorbol Acetate; Uveitis | 2014 |
Inflammation induces multinucleation of Microglia via PKC inhibition of cytokinesis, generating highly phagocytic multinucleated giant cells.
Topics: alpha-Synuclein; Amyloid beta-Peptides; Animals; Carbazoles; Cell Fusion; Cell Line; Cell Nucleus; Cytokinesis; Female; Giant Cells; Inflammation; Interferon-gamma; Interleukin-4; Lipopolysaccharides; Male; Mice; Microglia; PC12 Cells; Phagocytosis; Primary Cell Culture; Protein Kinase C; Protein Kinase Inhibitors; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2014 |
Anti-inflammatory R-prostaglandins from Caribbean Colombian soft coral Plexaura homomalla.
Topics: Animals; Anthozoa; Anti-Inflammatory Agents; Biological Products; Caribbean Region; Cell Degranulation; Colombia; Edema; Enzyme Inhibitors; Humans; Inflammation; Mice; Mice, Inbred ICR; Neutrophil Infiltration; Neutrophils; Pancreatic Elastase; Peroxidase; Prostaglandins; Tetradecanoylphorbol Acetate | 2013 |
In vivo anti-inflammatory properties of aerial parts of Nasturtium officinale.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Carrageenan; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Inflammation; Lethal Dose 50; Male; Mice; Nasturtium; Plant Components, Aerial; Plant Extracts; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate; Time Factors; Toxicity Tests, Acute | 2014 |
Phytosphingosine derivatives ameliorate skin inflammation by inhibiting NF-κB and JAK/STAT signaling in keratinocytes and mice.
Topics: Adult; Animals; Anti-Inflammatory Agents; Apoptosis; Cell Survival; Dermatitis; Humans; Inflammation; Interleukin-23; Janus Kinase 1; Keratinocytes; Leukocytes, Mononuclear; Male; MAP Kinase Signaling System; Mice; NF-kappa B; Psoriasis; Signal Transduction; Skin; Sphingosine; T-Lymphocytes; Tetradecanoylphorbol Acetate | 2014 |
SPION primes THP1 derived M2 macrophages towards M1-like macrophages.
Topics: B7-2 Antigen; Cathepsin L; Cell Differentiation; Cell Polarity; Cells, Cultured; Dextrans; Ferric Compounds; Ferritins; Humans; Immunoglobulin G; Inflammation; Macrophages; Magnetite Nanoparticles; Phagocytosis; Plaque, Atherosclerotic; Sterols; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Up-Regulation | 2013 |
Structural basis for inflammation-driven shedding of CD163 ectodomain and tumor necrosis factor-α in macrophages.
Topics: ADAM Proteins; ADAM17 Protein; Amino Acid Sequence; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Binding Sites; Cells, Cultured; Endotoxemia; Enzyme Precursors; HEK293 Cells; Humans; Immunoblotting; Inflammation; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Molecular Sequence Data; Mutation; Proteolysis; Receptors, Cell Surface; RNA Interference; Sequence Homology, Amino Acid; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2014 |
In vitro and in vivo anti-inflammatory effects of a novel 4,6-bis ((E)-4-hydroxy-3-methoxystyryl)-1-phenethylpyrimidine-2(1H)-thione.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2; Dose-Response Relationship, Drug; Female; Hep G2 Cells; Humans; Inflammation; Lipopolysaccharides; Mice; Molecular Structure; Nitric Oxide Synthase Type II; Pyrimidines; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Thiones; Tumor Cells, Cultured | 2014 |
Assessment of Augmented Immune Surveillance and Tumor Cell Death by Cytoplasmic Stabilization of p53 as a Chemopreventive Strategy of 3 Promising Medicinal Herbs in Murine 2-Stage Skin Carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antioxidants; Apoptosis; Calendula; Carcinogenesis; Cell Cycle Checkpoints; Cell Movement; Cell Proliferation; Chemoprevention; Eclipta; Female; Free Radicals; Immunologic Surveillance; Inflammation; Langerhans Cells; Mice; NF-kappa B; Phytotherapy; Plant Extracts; Proliferating Cell Nuclear Antigen; Signal Transduction; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Trigonella; Tumor Suppressor Protein p53 | 2014 |
Silibinin inhibits tumor promotional triggers and tumorigenesis against chemically induced two-stage skin carcinogenesis in Swiss albino mice: possible role of oxidative stress and inflammation.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Carcinogenesis; Catalase; Cell Transformation, Neoplastic; Chemoprevention; Cyclooxygenase 2; Down-Regulation; Female; Glucosephosphate Dehydrogenase; Inflammation; Interleukin-1beta; Interleukin-6; Lipid Peroxidation; Mice; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidative Stress; Silybin; Silymarin; Skin; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Up-Regulation; Vascular Endothelial Growth Factor A | 2014 |
Pro- and anti-inflammatory effects of histamine on tissue factor and TNFα expression in monocytes of human blood.
Topics: Dose-Response Relationship, Drug; Drug Synergism; Histamine; Humans; Inflammation; Lipopolysaccharides; Monocytes; Tetradecanoylphorbol Acetate; Thromboplastin; Tumor Necrosis Factor-alpha | 2014 |
IDO2 is critical for IDO1-mediated T-cell regulation and exerts a non-redundant function in inflammation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cytokines; Dendritic Cells; Female; Gene Expression Regulation; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Kynurenine; Lymphocyte Culture Test, Mixed; Male; Mice; Mice, Knockout; Papilloma; Signal Transduction; Skin Neoplasms; T-Lymphocytes, Regulatory; Tetradecanoylphorbol Acetate; Th1-Th2 Balance | 2014 |
S100A9 has a protective role in inflammation-induced skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Calgranulin A; Calgranulin B; Carcinogenesis; Cell Transformation, Neoplastic; Dimerization; Female; Gene Deletion; Gene Expression Regulation, Neoplastic; Inflammation; Keratinocytes; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neutrophils; Skin Neoplasms; T-Lymphocytes; Tetradecanoylphorbol Acetate | 2014 |
Probiotic Lactobacillus rhamnosus inhibits the formation of neutrophil extracellular traps.
Topics: Animals; Cell Line; Cytotoxicity, Immunologic; Extracellular Matrix; HL-60 Cells; Humans; Immunity, Innate; Inflammation; Inflammatory Bowel Diseases; Intestines; Lacticaseibacillus rhamnosus; Mice; Mice, Inbred C57BL; Neutrophils; Phagocytosis; Probiotics; Reactive Oxygen Species; Staphylococcus aureus; Tetradecanoylphorbol Acetate | 2014 |
Caffeic acid reduces cutaneous tumor necrosis factor alpha (TNF-α), IL-6 and IL-1β levels and ameliorates skin edema in acute and chronic model of cutaneous inflammation in mice.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Caffeic Acids; Dermatitis, Contact; Dose-Response Relationship, Drug; Edema; Humans; Inflammation; Inflammation Mediators; Interleukin-1beta; Interleukin-6; Keratinocytes; Mice; Mice, Inbred BALB C; Neutrophils; NF-kappa B; Peroxidase; Plant Extracts; RNA, Messenger; Skin; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2014 |
Selective inhibition of protein kinase C β2 attenuates the adaptor P66 Shc-mediated intestinal ischemia-reperfusion injury.
Topics: Animals; Apoptosis; Caco-2 Cells; Cell Hypoxia; Cell Membrane; Enzyme Activation; Humans; Inflammation; Intestines; Male; Mice, Inbred ICR; Oxidative Stress; Phosphorylation; Protein Kinase C beta; Protein Kinase Inhibitors; Protein Transport; Reperfusion Injury; Shc Signaling Adaptor Proteins; Src Homology 2 Domain-Containing, Transforming Protein 1; Tetradecanoylphorbol Acetate | 2014 |
Zinc oxide nanoparticles, a novel candidate for the treatment of allergic inflammatory diseases.
Topics: Animals; Anti-Inflammatory Agents; Calcimycin; Caspase 1; Cell Line; Cytokines; Enzyme Activation; Gene Expression Regulation; Humans; Hypersensitivity; I-kappa B Kinase; Inflammation; Male; Mast Cells; Mice; Mitogen-Activated Protein Kinases; Nanoparticles; NF-kappa B; Passive Cutaneous Anaphylaxis; Phosphorylation; Proteolysis; Receptor-Interacting Protein Serine-Threonine Kinase 2; RNA, Messenger; Tetradecanoylphorbol Acetate; Zinc Oxide | 2014 |
Topical application of the adenosine A2A receptor agonist CGS-21680 prevents phorbol-induced epidermal hyperplasia and inflammation in mice.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Administration, Topical; Animals; Anti-Inflammatory Agents; Cell Proliferation; Collagen; Cytokines; Dexamethasone; Disease Models, Animal; Epidermis; Female; Hyperplasia; Inflammation; Mice; Peroxidase; Phenethylamines; Skin Diseases; Tetradecanoylphorbol Acetate | 2014 |
Lycopene modulates THP1 and Caco2 cells inflammatory state through transcriptional and nontranscriptional processes.
Topics: Antioxidants; beta-Galactosidase; Caco-2 Cells; Carotenoids; Cell Line; Cyclic AMP; Gene Expression Profiling; Gene Expression Regulation; Humans; Inflammation; Lipopolysaccharides; Lycopene; Matrix Metalloproteinase 9; Monocytes; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Necrosis Factor-alpha | 2014 |
Analysis of IL-17 production by flow cytometry and ELISPOT assays.
Topics: Animals; Antibodies; Brefeldin A; Enzyme-Linked Immunospot Assay; Female; Flow Cytometry; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Humans; Inflammation; Interleukin-17; Interleukin-6; Ionomycin; Mice; Mice, Inbred C57BL; Phycoerythrin; Quinolinium Compounds; Tetradecanoylphorbol Acetate; Th17 Cells; Transforming Growth Factor beta | 2014 |
Production of the anti-inflammatory compound 6-O-palmitoyl-3-O-β-D-glucopyranosylcampesterol by Callus cultures of Lopezia racemosa Cav. (Onagraceae).
Topics: Animals; Anti-Inflammatory Agents; Cells, Cultured; Cholesterol; Ear; Edema; Germination; Inflammation; Male; Mice; Onagraceae; Phytochemicals; Phytosterols; Plant Extracts; Seeds; Tetradecanoylphorbol Acetate | 2014 |
Suppressive effects of britanin, a sesquiterpene compound isolated from Inulae flos, on mast cell-mediated inflammatory responses.
Topics: Administration, Ophthalmic; Animals; Calcimycin; Calcium Ionophores; Cells, Cultured; Cytokines; Dose-Response Relationship, Drug; Humans; Hypersensitivity, Immediate; Inflammation; Inflammation Mediators; Inula; Lactones; Male; Mast Cells; Mice, Inbred ICR; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Passive Cutaneous Anaphylaxis; Phosphorylation; Phytotherapy; Sesquiterpenes; Tetradecanoylphorbol Acetate | 2014 |
An aqueous extract of Ilex paraguariensis reduces carrageenan-induced edema and inhibits the expression of cyclooxygenase-2 and inducible nitric oxide synthase in animal models of inflammation.
Topics: Animals; Carrageenan; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Edema; Female; Ilex paraguariensis; Inflammation; Mice, Inbred Strains; Nitric Oxide Synthase Type II; Phenols; Phytotherapy; Plant Extracts; Skin; Tetradecanoylphorbol Acetate | 2014 |
Genome-wide analysis of DNA methylation in UVB- and DMBA/TPA-induced mouse skin cancer models.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; CpG Islands; Disease Models, Animal; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Genome; Inflammation; Mice; Sequence Analysis, DNA; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 2014 |
Galectin-3, a biomarker linking oxidative stress and inflammation with the clinical outcomes of patients with atherothrombosis.
Topics: Aged; Biomarkers; Carotid Artery Diseases; Carotid Intima-Media Thickness; Case-Control Studies; Cell Line; Female; Follow-Up Studies; Galectin 3; Humans; In Vitro Techniques; Inflammation; Macrophages; Male; Middle Aged; Monocytes; NADPH Oxidases; Oxidative Stress; Peripheral Arterial Disease; Prognosis; Tetradecanoylphorbol Acetate | 2014 |
Monosodium urate crystals trigger Nrf2- and heme oxygenase-1-dependent inflammation in THP-1 cells.
Topics: Carrier Proteins; Cell Line, Tumor; Gout; Heme Oxygenase-1; Humans; Inflammation; Interleukin-1beta; Lysosomes; NF-E2-Related Factor 2; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidation-Reduction; Protoporphyrins; Reactive Oxygen Species; Signal Transduction; Tetradecanoylphorbol Acetate; Uric Acid | 2015 |
Macrophage migration inhibitory factor triggers chemotaxis of CD74+CXCR2+ NKT cells in chemically induced IFN-γ-mediated skin inflammation.
Topics: Acute Disease; Animals; Antigens, Differentiation, B-Lymphocyte; Carcinogens; Cell Line; Chronic Disease; Disease Models, Animal; Drug Eruptions; Epidermis; Histocompatibility Antigens Class II; Humans; Inflammation; Interferon-gamma; Intramolecular Oxidoreductases; Keratinocytes; Macrophage Migration-Inhibitory Factors; Mice; Natural Killer T-Cells; Neovascularization, Pathologic; Receptors, Interleukin-8B; Tetradecanoylphorbol Acetate | 2014 |
Neutrophil extracellular traps formation by bacteria causing endometritis in the mare.
Topics: Animals; Cells, Cultured; Cytochalasins; Endometritis; Escherichia coli; Extracellular Traps; Female; Horses; Inflammation; Neutrophils; Peroxidase; Phagocytosis; Staphylococcus; Streptococcus equi; Tetradecanoylphorbol Acetate | 2014 |
Tat-biliverdin reductase A inhibits inflammatory response by regulation of MAPK and NF-κB pathways in Raw 264.7 cells and edema mouse model.
Topics: Animals; Cell Line; Cell Survival; Disease Models, Animal; Edema; Humans; Inflammation; Lipopolysaccharides; Macrophages; Male; Mice, Inbred ICR; Mitogen-Activated Protein Kinases; NF-kappa B; Oxidative Stress; Oxidoreductases Acting on CH-CH Group Donors; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Recombinant Fusion Proteins; Signal Transduction; tat Gene Products, Human Immunodeficiency Virus; Tetradecanoylphorbol Acetate; Transduction, Genetic | 2015 |
Psoriatic inflammation facilitates the onset of arthritis in a mouse model.
Topics: Animals; Arthritis, Psoriatic; Cytokines; Disease Models, Animal; Inflammation; Joint Diseases; Mice; Mice, Inbred C57BL; Psoriasis; Skin Diseases; STAT3 Transcription Factor; Tetradecanoylphorbol Acetate; Th17 Cells | 2015 |
Afadin requirement for cytokine expressions in keratinocytes during chemically induced inflammation in mice.
Topics: Animals; Chemokine CXCL2; Epidermis; Inflammation; Interleukin-1beta; Keratinocytes; Mice; Mice, Knockout; Microfilament Proteins; Neutrophils; Primary Cell Culture; rap1 GTP-Binding Proteins; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2014 |
Piceatannol inhibits phorbol ester-induced expression of COX-2 and iNOS in HR-1 hairless mouse skin by blocking the activation of NF-κB and AP-1.
Topics: Animals; Catalysis; Catalytic Domain; Cyclooxygenase 2; Female; I-kappa B Kinase; Immunohistochemistry; Inflammation; Mice; NF-kappa B; Nitric Oxide Synthase Type II; Phosphorylation; Protein Binding; Proto-Oncogene Proteins c-fos; Skin; Stilbenes; Tetradecanoylphorbol Acetate; Transcription Factor AP-1 | 2014 |
Berteroin present in cruciferous vegetables exerts potent anti-inflammatory properties in murine macrophages and mouse skin.
Topics: Animals; Anti-Inflammatory Agents; Cyclooxygenase 2; Cytokines; Female; I-kappa B Proteins; Inflammation; Isothiocyanates; Lipopolysaccharides; Macrophages; Mice; NF-KappaB Inhibitor alpha; Nitric Oxide; Nitric Oxide Synthase Type II; Skin; Tetradecanoylphorbol Acetate; Vegetables | 2014 |
Suppression of skin inflammation in keratinocytes and acute/chronic disease models by caffeic acid phenethyl ester.
Topics: Acute Disease; Animals; Caffeic Acids; Cell Line; Chronic Disease; Cyclooxygenase 2; Dermatitis, Atopic; Disease Models, Animal; Humans; Immunoglobulin E; Inflammation; Keratinocytes; Mice; Mice, Inbred Strains; NF-kappa B; Oxazolone; Phenylethyl Alcohol; Propolis; Skin; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Water Loss, Insensible | 2015 |
Anti-inflammatory effect of natural and semi-synthetic phthalides.
Topics: Animals; Anti-Inflammatory Agents; Benzofurans; Biological Products; Carrageenan; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Edema; Inflammation; Male; Mice; Nitric Oxide Synthase; Nitrites; Peroxidase; RAW 264.7 Cells; Skin; Tetradecanoylphorbol Acetate | 2015 |
Progranulin is preferentially expressed in patients with psoriasis vulgaris and protects mice from psoriasis-like skin inflammation.
Topics: Adult; Animals; Carcinogens; Cell Differentiation; Disease Models, Animal; Female; Gene Expression Regulation; Granulins; Humans; Inflammation; Intercellular Signaling Peptides and Proteins; Male; Mice; Mice, Knockout; Middle Aged; Progranulins; Psoriasis; Skin; T-Lymphocytes, Regulatory; Tetradecanoylphorbol Acetate | 2015 |
Anti-inflammatory effects of zinc in PMA-treated human gingival fibroblast cells.
Topics: Cells, Cultured; Cytokines; Fibroblasts; Gingiva; Humans; Inflammation; Tetradecanoylphorbol Acetate; Zinc | 2015 |
Curcumin relieves TPA-induced Th1 inflammation in K14-VEGF transgenic mice.
Topics: Animals; Anti-Inflammatory Agents; Curcumin; Cytokines; Disease Models, Animal; Gels; Inflammation; Mice, Transgenic; Nuclear Receptor Subfamily 1, Group F, Member 3; Psoriasis; Receptors, Antigen, T-Cell, gamma-delta; Receptors, CCR6; RNA, Messenger; Skin; Tetradecanoylphorbol Acetate; Th1 Cells | 2015 |
Tocopherol isoforms (α-, γ-, and δ-) show distinct capacities to control Nrf-2 and NfκB signaling pathways that modulate inflammatory response in Caco-2 intestinal cells.
Topics: alpha-Tocopherol; Antioxidants; Caco-2 Cells; gamma-Tocopherol; Gene Expression Regulation; Humans; Inflammation; Interleukin-8; NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress; Protein Isoforms; Reactive Oxygen Species; Signal Transduction; Tetradecanoylphorbol Acetate; Tocopherols | 2015 |
5-O-Acyl plumbagins inhibit DNA polymerase activity and suppress the inflammatory response.
Topics: Animals; Anti-Inflammatory Agents; Cell Line; DNA Polymerase beta; Escherichia coli Proteins; Fatty Acids; Gene Knockdown Techniques; Humans; Inflammation; Lipopolysaccharides; Macrophages; Mice; Naphthoquinones; Plant Proteins; Rats; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2015 |
Keratinocyte p38δ loss inhibits Ras-induced tumor formation, while systemic p38δ loss enhances skin inflammation in the early phase of chemical carcinogenesis in mouse skin.
Topics: Animals; Benz(a)Anthracenes; Cell Transformation, Neoplastic; Inflammation; Mice; Mice, Nude; Mitogen-Activated Protein Kinase 13; ras Proteins; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2016 |
Cancer-promoting effect of capsaicin on DMBA/TPA-induced skin tumorigenesis by modulating inflammation, Erk and p38 in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Capsaicin; Carcinogenesis; Cyclooxygenase 2; Female; Hyperplasia; Inflammation; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Mice; Mice, Inbred ICR; NF-kappa B; Nitric Oxide Synthase Type II; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Up-Regulation | 2015 |
Chemopreventive efficacy of menthol on carcinogen-induced cutaneous carcinoma through inhibition of inflammation and oxidative stress in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Anticarcinogenic Agents; Carcinogens; Carcinoma; Chemoprevention; Cyclooxygenase 2; Dermatitis; Female; Glutathione; Inflammation; Menthol; Mice, Inbred ICR; Neoplasms, Experimental; Oxidative Stress; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2015 |
Shaping mycolactone for therapeutic use against inflammatory disorders.
Topics: Animals; Chronic Disease; HeLa Cells; Humans; Immunomodulation; Inflammation; Jurkat Cells; Macrolides; Mice; Mycobacterium ulcerans; Pain; Protective Agents; Tetradecanoylphorbol Acetate | 2015 |
Effect of Combined Treatment with Ursolic Acid and Resveratrol on Skin Tumor Promotion by 12-O-Tetradecanoylphorbol-13-Acetate.
Topics: Animals; Anticarcinogenic Agents; Carcinogenesis; Cell Nucleus; Cell Proliferation; Cytosol; Female; Inflammation; Male; Mice; Mice, Inbred ICR; Protein Binding; Resveratrol; Signal Transduction; Skin; Skin Neoplasms; Stilbenes; Tetradecanoylphorbol Acetate; Triterpenes; Ursolic Acid | 2015 |
Hematopoietic plakophilin-3 regulates acute tissue-specific and systemic inflammation in mice.
Topics: Animals; Colitis; Dermatitis, Contact; Dextran Sulfate; Gene Expression Regulation; Inflammation; Lipopolysaccharides; Mice; Mice, Knockout; Neutrophils; Plakophilins; Tetradecanoylphorbol Acetate | 2015 |
Artificial Loading of ASC Specks with Cytosolic Antigens.
Topics: Antigen Presentation; Antigens; Calcium-Binding Proteins; CARD Signaling Adaptor Proteins; Carrier Proteins; Caspase 1; Cell Differentiation; Cytoskeleton; Cytosol; DNA-Binding Proteins; Green Fluorescent Proteins; HEK293 Cells; Humans; Inflammasomes; Inflammation; Macrophages; NLR Family, Pyrin Domain-Containing 3 Protein; Ovalbumin; Proteasome Endopeptidase Complex; Tetradecanoylphorbol Acetate; Ubiquitin | 2015 |
The effect of differentiation agents on inflammatory and oxidative responses of the human neuroblastoma cell line SK-N-SH.
Topics: Antineoplastic Agents; Caspase 3; Caspase 7; Cell Differentiation; Cell Line, Tumor; Cytokines; Free Radicals; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Inflammation; Neuroblastoma; Neurons; Nitric Oxide; Nitrites; Oxidative Stress; Oxygen; Phenotype; Tetradecanoylphorbol Acetate; Tretinoin | 2015 |
Potent inhibitory effect of silibinin from milk thistle on skin inflammation stimuli by 12-O-tetradecanoylphorbol-13-acetate.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Cyclooxygenase 2; Dermatitis; Dose-Response Relationship, Drug; Female; Inflammation; Interleukin-1beta; Interleukin-6; Mice; Mice, Inbred BALB C; NF-kappa B; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; Silybin; Silybum marianum; Silymarin; Skin; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2015 |
Trichostatin A inhibits inflammation in phorbol myristate acetate‑induced macrophages by regulating the acetylation of histone and/or non‑histone proteins.
Topics: Acetylation; Apoptosis; Cell Line, Tumor; Cell Survival; Cytokines; Dose-Response Relationship, Drug; Gene Expression Regulation; Histone Deacetylases; Histones; Humans; Hydroxamic Acids; Inflammation; Macrophages; Tetradecanoylphorbol Acetate; Transcription Factor RelA | 2016 |
Inflammation increases NOTCH1 activity via MMP9 and is counteracted by Eicosapentaenoic Acid-free fatty acid in colon cancer cells.
Topics: Cell Differentiation; Cell Line; Cell Movement; Culture Media, Conditioned; Cytokines; Eicosapentaenoic Acid; Epithelial-Mesenchymal Transition; Gene Expression Regulation; HCT116 Cells; HT29 Cells; Humans; Inflammation; Lipopolysaccharides; Matrix Metalloproteinase 9; Monocytes; Receptor, Notch1; Signal Transduction; Tetradecanoylphorbol Acetate | 2016 |
Aqueous and Ethanol Extracts of Australian Cane Toad Skins Suppress Pro-Inflammatory Cytokine Secretion in U937 Cells via NF-κB Signaling Pathway.
Topics: Animals; Anti-Inflammatory Agents; Anura; Apoptosis; Biological Products; Blotting, Western; Bufanolides; Cardiotonic Agents; Cell Proliferation; Cytokines; Ethanol; Fluorescent Antibody Technique; Humans; Inflammation; Interleukin-6; Lipopolysaccharides; Monocytes; NF-kappa B; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Skin; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2016 |
Resveratrol attenuates monocyte-to-macrophage differentiation and associated inflammation via modulation of intracellular GSH homeostasis: Relevance in atherosclerosis.
Topics: Acetylcysteine; AMP-Activated Protein Kinases; Animals; Antioxidants; Apolipoproteins E; Atherosclerosis; Buthionine Sulfoximine; Cell Differentiation; Glutathione; Homeostasis; Humans; Inflammation; Macrophages; Matrix Metalloproteinase 9; Mice; Mice, Knockout; Monocytes; Resveratrol; Stilbenes; Tetradecanoylphorbol Acetate | 2016 |
Alpinetin attenuates inflammatory responses by suppressing TLR4 and NLRP3 signaling pathways in DSS-induced acute colitis.
Topics: Animals; Cell Survival; Colitis; Dextran Sulfate; Female; Flavanones; Humans; Inflammasomes; Inflammation; Injections, Intraperitoneal; Interleukin-1beta; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred BALB C; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Peroxidase; Signal Transduction; Tetradecanoylphorbol Acetate; THP-1 Cells; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2016 |
Selective inhibition of JAK2/STAT1 signaling and iNOS expression mediates the anti-inflammatory effects of coniferyl aldehyde.
Topics: Acrolein; Animals; Anti-Inflammatory Agents; Carrageenan; Cell Line; Down-Regulation; Ear; Edema; Humans; Inflammation; Janus Kinase 2; Lipopolysaccharides; Macrophages; Male; Mice; Mice, Inbred ICR; Nitric Oxide; Nitric Oxide Synthase Type II; Rats, Sprague-Dawley; RAW 264.7 Cells; Signal Transduction; STAT1 Transcription Factor; Tetradecanoylphorbol Acetate | 2016 |
EXPRESS: F-actin links Epac-PKC signaling to purinergic P2X3 receptors sensitization in dorsal root ganglia following inflammation.
Topics: Actins; Adenosine Triphosphate; Animals; Cell Membrane; Cyclic AMP; Cytochalasin D; Dinoprostone; Freund's Adjuvant; Ganglia, Spinal; Guanine Nucleotide Exchange Factors; Hyperalgesia; Inflammation; Male; Neurons; Protein Kinase C; Rats, Sprague-Dawley; Receptors, Purinergic P2X3; Signal Transduction; Tetradecanoylphorbol Acetate; Thionucleotides | 2016 |
Effect of 12-O-tetradecanoylphorbol-13-acetate-induced psoriasis-like skin lesions on systemic inflammation and atherosclerosis in hypercholesterolaemic apolipoprotein E deficient mice.
Topics: Animals; Apolipoproteins E; Atherosclerosis; Carcinogens; Cytokines; Disease Models, Animal; Hypercholesterolemia; Inflammation; Mice; Mice, Transgenic; Psoriasis; RNA, Messenger; Serum Amyloid A Protein; Spleen; Tetradecanoylphorbol Acetate | 2016 |
Panx3 links body mass index and tumorigenesis in a genetically heterogeneous mouse model of carcinogen-induced cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Mass Index; Carcinogenesis; Carcinogens; Connexins; Crosses, Genetic; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Genetic Predisposition to Disease; Humans; Inflammation; Lipid Metabolism; Male; Mice; Mice, Inbred Strains; Quantitative Trait Loci; Sex Factors; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2016 |
Potential role of IL-17-producing CD4/CD8 double negative αβ T cells in psoriatic skin inflammation in a TPA-induced STAT3C transgenic mouse model.
Topics: Animals; CD4 Antigens; CD8 Antigens; Disease Models, Animal; Flow Cytometry; Humans; Immunohistochemistry; Inflammation; Interleukin-17; Interleukin-23 Subunit p19; Mice; Mice, Transgenic; Nuclear Receptor Subfamily 1, Group F, Member 3; Psoriasis; Receptors, CCR6; Skin; STAT3 Transcription Factor; T-Lymphocyte Subsets; Tetradecanoylphorbol Acetate | 2017 |
Novel involvement of miR-522-3p in high-mobility group box 1-induced prostaglandin reductase 1 expression and reduction of phagocytosis.
Topics: Alcohol Oxidoreductases; Base Sequence; Cell Differentiation; Cell Line; Cell Line, Tumor; Epithelial Cells; Gene Expression Regulation; HMGB1 Protein; Humans; Inflammation; Lipopolysaccharides; Macrophages; MicroRNAs; Monocytes; Oligoribonucleotides; Phagocytosis; RNA, Small Interfering; Signal Transduction; Tetradecanoylphorbol Acetate | 2017 |
Pramipexole reduces inflammation in the experimental animal models of inflammation.
Topics: Animals; Anti-Inflammatory Agents; Benzothiazoles; Carrageenan; Disease Models, Animal; Inflammation; Male; Mice; Parkinson Disease, Secondary; Pramipexole; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate | 2017 |
Hemin inhibits cyclooxygenase-2 expression through nuclear factor-kappa B activation and ornithine decarboxylase expression in 12-O-tetradecanoylphorbol-13-acetate-treated mouse skin.
Topics: Animals; Anti-Inflammatory Agents; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dermatitis; Enzyme Activation; Female; Hemin; Inflammation; Mice; Mice, Inbred ICR; Mitogen-Activated Protein Kinases; NF-kappa B; Ornithine Decarboxylase; Skin; Tetradecanoylphorbol Acetate | 2008 |
Proteinase 3 and neutrophil elastase enhance inflammation in mice by inactivating antiinflammatory progranulin.
Topics: Animals; Antigen-Antibody Complex; Arthus Reaction; Cell Movement; Chemotaxis, Leukocyte; Granulins; Inflammation; Intercellular Signaling Peptides and Proteins; Leukocyte Elastase; Mice; Mice, Inbred Strains; Mice, Knockout; Models, Biological; Myeloblastin; Neutrophil Activation; Neutrophils; Ovalbumin; Progranulins; Respiratory Burst; Tetradecanoylphorbol Acetate | 2008 |
High-density lipoprotein reduces the human monocyte inflammatory response.
Topics: Actins; Apolipoprotein A-I; Atherosclerosis; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; CD11b Antigen; Cell Adhesion; Cell Shape; Cells, Cultured; Cholesterol; Cyclodextrins; Endothelial Cells; Humans; Inflammation; Lipoproteins, HDL; Membrane Microdomains; Monocytes; Platelet Adhesiveness; Scavenger Receptors, Class B; Stress, Mechanical; Tangier Disease; Tetradecanoylphorbol Acetate; Time Factors | 2008 |
Resveratrol modulates innate and inflammatory responses in fish leucocytes.
Topics: Animals; Cell Movement; Cells, Cultured; Dinoprostone; Flatfishes; Gene Expression Regulation; Immunity, Innate; Inflammation; Kidney; Leukocytes; Peroxidase; Respiratory Burst; Resveratrol; Stilbenes; Tetradecanoylphorbol Acetate | 2008 |
The role of P38 MAPK and PKC in BLP induced TNF-alpha release, apoptosis, and NFkappaB activation in THP-1 monocyte cells.
Topics: Apoptosis; Bacterial Proteins; Cell Line; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Imidazoles; Indoles; Inflammation; Lipopolysaccharides; Lipoproteins; Maleimides; Monocytes; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Protein Kinase C; Pyridines; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2009 |
Lithospermic acid as a novel xanthine oxidase inhibitor has anti-inflammatory and hypouricemic effects in rats.
Topics: Allopurinol; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Gouty; Benzofurans; Depsides; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Hyperuricemia; Inflammation; Male; Molecular Conformation; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxonic Acid; Rats; Rats, Wistar; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Uric Acid; Xanthine Oxidase | 2008 |
Regulatory T cells control VEGF-dependent skin inflammation.
Topics: Animals; CD4 Antigens; CD4-Positive T-Lymphocytes; Cell Separation; Flow Cytometry; Inflammation; Interleukin-2 Receptor alpha Subunit; Mice; Mice, Transgenic; Neovascularization, Pathologic; Skin; T-Lymphocytes, Regulatory; Tetradecanoylphorbol Acetate; Vascular Endothelial Growth Factor A | 2009 |
Effects of short chain fatty acids on effector mechanisms of neutrophils.
Topics: Animals; Bacteria; Candida albicans; Carcinogens; Fatty Acids, Volatile; Inflammation; Male; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Phagocytosis; Rats; Rats, Wistar; Reactive Oxygen Species; Tetradecanoylphorbol Acetate | 2009 |
Dietary grape seed proanthocyanidins inhibit 12-O-tetradecanoyl phorbol-13-acetate-caused skin tumor promotion in 7,12-dimethylbenz[a]anthracene-initiated mouse skin, which is associated with the inhibition of inflammatory responses.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cyclin D1; Cyclooxygenase 2; Dinoprostone; Female; Grape Seed Extract; Inflammation; Mice; Papilloma; Plant Extracts; Proanthocyanidins; Proliferating Cell Nuclear Antigen; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2009 |
Perillyl alcohol attenuates Ras-ERK signaling to inhibit murine skin inflammation and tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Apoptosis; Disease Models, Animal; Drug Screening Assays, Antitumor; Edema; Extracellular Signal-Regulated MAP Kinases; Female; Hyperplasia; Inflammation; Mice; Monoterpenes; Oxidative Stress; ras Proteins; Signal Transduction; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 2009 |
Anti-inflammatory activities of methanol extracts from various seaweed species.
Topics: Animals; Anti-Inflammatory Agents; Blood Flow Velocity; Dose-Response Relationship, Drug; Ear; Edema; Erythema; Inflammation; Inhibitory Concentration 50; Korea; Methanol; Mice; Mice, Inbred BALB C; Plant Extracts; Seaweed; Tetradecanoylphorbol Acetate | 2008 |
A TLR2 ligand suppresses inflammation by modulation of chemokine receptors and redirection of leukocyte migration.
Topics: Animals; Cell Movement; Cells, Cultured; Chemokines; Female; Flow Cytometry; Inflammation; Interferon-gamma; Leukocytes; Ligands; Lipoproteins; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-kappa B; Receptors, Chemokine; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Skin; Tetradecanoylphorbol Acetate; Toll-Like Receptor 2 | 2009 |
Vernonia cinerea L. scavenges free radicals and regulates nitric oxide and proinflammatory cytokines profile in carrageenan induced paw edema model.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Blood; C-Reactive Protein; Carrageenan; Cytokines; Edema; Enzymes; Free Radical Scavengers; Free Radicals; Gene Expression; Hydroxyl Radical; Inflammation; Lipid Peroxidation; Lipopolysaccharides; Liver; Macrophages, Peritoneal; Male; Mice; Mice, Inbred BALB C; Nitric Oxide; Plant Extracts; Superoxides; Tetradecanoylphorbol Acetate; Vernonia | 2009 |
IFNgamma promotes papilloma development by up-regulating Th17-associated inflammation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Inflammation; Interferon gamma Receptor; Interferon-gamma; Interleukin-17; Mice; Papilloma; Phosphorylation; Receptors, Interferon; Skin Neoplasms; STAT1 Transcription Factor; Tetradecanoylphorbol Acetate | 2009 |
Activation of equine neutrophils by phorbol myristate acetate or N-formyl-methionyl-leucyl-phenylalanine induces a different response in reactive oxygen species production and release of active myeloperoxidase.
Topics: Animals; Biphenyl Compounds; Cell Degranulation; Cytochalasin B; Ethylenes; Horse Diseases; Horses; In Vitro Techniques; Inflammation; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Onium Compounds; Peroxidase; Reactive Oxygen Species; Superoxide Dismutase; Tetradecanoylphorbol Acetate | 2009 |
The anti-inflammatory effects of methylsulfonylmethane on lipopolysaccharide-induced inflammatory responses in murine macrophages.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Cell Line; Cell Survival; Cytokines; Dimethyl Sulfoxide; Dinoprostone; Female; I-kappa B Proteins; Inflammation; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred ICR; Nitric Oxide; Nitrites; Sulfones; Tetradecanoylphorbol Acetate; Transcription Factor RelA | 2009 |
ASB16165, a phosphodiesterase 7A inhibitor, reduces cutaneous TNF-alpha level and ameliorates skin edema in phorbol ester 12-O-tetradecanoylphorbol-13-acetate-induced skin inflammation model in mice.
Topics: Animals; Cyclic Nucleotide Phosphodiesterases, Type 7; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Enzyme Inhibitors; Epidermis; Female; Gene Expression Regulation; Humans; Inflammation; Keratinocytes; Mice; Mice, Inbred BALB C; Pyrazoles; Skin; Tetradecanoylphorbol Acetate; Thiophenes; Tumor Necrosis Factor-alpha | 2009 |
Anti-inflammatory effects of ethanolic extract and alkamides-derived from Heliopsis longipes roots.
Topics: Alkanes; Amides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Asteraceae; Ear, External; Edema; Ethanol; Indicators and Reagents; Inflammation; Mice; Plant Extracts; Plant Roots; Polyunsaturated Alkamides; Solvents; Tetradecanoylphorbol Acetate | 2009 |
Chemopreventive effect of farnesol on DMBA/TPA-induced skin tumorigenesis: involvement of inflammation, Ras-ERK pathway and apoptosis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Apoptosis; Chemoprevention; Cyclooxygenase 2; Disease Models, Animal; Drug Screening Assays, Antitumor; Extracellular Signal-Regulated MAP Kinases; Farnesol; Inflammation; Mice; Ornithine Decarboxylase; Oxidative Stress; ras Proteins; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2009 |
Anti-edema effects of brown seaweed (Undaria pinnatifida) extract on phorbol 12-myristate 13-acetate-induced mouse ear inflammation.
Topics: Animals; Edema; Inflammation; Mice; Mice, Inbred BALB C; Plant Extracts; Seaweed; Tetradecanoylphorbol Acetate | 2009 |
Anti-inflammatory activity of Motherwort (Leonurus sibiricus L.).
Topics: Anti-Inflammatory Agents; Calcimycin; Humans; Inflammation; Interleukin-6; Interleukin-8; Leonurus; Mast Cells; Medicine, Traditional; NF-kappa B; Phytotherapy; Plant Extracts; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2009 |
Anti-tumor promoters phenolics and triterpenoid from Hippophae rhamnoides.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anti-Inflammatory Agents; Antineoplastic Agents, Phytogenic; Catechin; Female; Hippophae; Inflammation; Mice; Mice, Inbred ICR; Phytotherapy; Plant Extracts; Plant Stems; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2009 |
Antinociceptive and anti-allodynic effects of 3-alkynyl selenophene on different models of nociception in mice.
Topics: Analgesics; Animals; Bradykinin; Capsaicin; Formaldehyde; Freund's Adjuvant; Glutamic Acid; Hot Temperature; Hyperalgesia; Immersion; Inflammation; Male; Mice; Motor Activity; Organoselenium Compounds; Pain Measurement; Reaction Time; Tetradecanoylphorbol Acetate | 2009 |
Fullerene nanomaterials inhibit phorbol myristate acetate-induced inflammation.
Topics: Animals; Dermatitis, Contact; Ear Auricle; Edema; Fullerenes; Inflammation; Injections, Subcutaneous; Male; Mice; Mice, Inbred Strains; Molecular Structure; Nanostructures; Tetradecanoylphorbol Acetate | 2009 |
The role of mitogen-activated protein kinase-activated protein kinase 2 in the p38/TNF-alpha pathway of systemic and cutaneous inflammation.
Topics: Animals; Dermatitis, Contact; Dinitrofluorobenzene; Female; Granulocytes; Homozygote; Inflammation; Intracellular Signaling Peptides and Proteins; Mice; Mice, Inbred C57BL; p38 Mitogen-Activated Protein Kinases; Protein Serine-Threonine Kinases; Receptors, Antigen, T-Cell; Skin; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2010 |
Relative inhibitory activity of bile acids against 12-O-tetradecanoylphorbol-13-acetate-induced inflammation, and chenodeoxycholic acid inhibition of tumour promotion in mouse skin two-stage carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anti-Inflammatory Agents; Anticarcinogenic Agents; Bile Acids and Salts; Carcinogens; Chenodeoxycholic Acid; Disease Models, Animal; Edema; Female; Indomethacin; Inflammation; Inhibitory Concentration 50; Mice; Mice, Inbred ICR; Neoplasms, Experimental; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 2009 |
IL-12 deficiency suppresses 12-O-tetradecanoylphorbol-13-acetate-induced skin tumor development in 7,12-dimethylbenz(a)anthracene-initiated mouse skin through inhibition of inflammation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cyclin D1; Cyclooxygenase 2; Cytokines; Female; Inflammation; Interleukin-12 Subunit p40; Interleukin-6; Mice; Mice, Knockout; Proliferating Cell Nuclear Antigen; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2009 |
Benzyl isothiocyanate exhibits anti-inflammatory effects in murine macrophages and in mouse skin.
Topics: Animals; Anti-Inflammatory Agents; Cell Line; Cyclooxygenase 2; Down-Regulation; Ear; Edema; Humans; Inflammation; Isothiocyanates; Lipopolysaccharides; Macrophages; Male; Mice; Mice, Inbred ICR; NF-kappa B; Nitric Oxide Synthase Type II; Signal Transduction; Skin; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2009 |
MK2 regulates the early stages of skin tumor promotion.
Topics: Animals; Apoptosis; Disease Progression; DNA Damage; Gene Expression Regulation, Neoplastic; Inflammation; Intracellular Signaling Peptides and Proteins; Keratinocytes; Mice; Mice, Transgenic; Phosphorylation; Protein Serine-Threonine Kinases; RNA, Small Interfering; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Tumor Suppressor Protein p53 | 2009 |
Quantification and phenotype of regulatory T cells in rheumatoid arthritis according to disease activity score-28.
Topics: Aged; Antigens, CD; Arthritis, Rheumatoid; CD4 Lymphocyte Count; CTLA-4 Antigen; Female; Forkhead Transcription Factors; Humans; Immunophenotyping; Inflammation; Interferon-gamma; Interleukin-10; Interleukin-2 Receptor alpha Subunit; Ionomycin; Male; Middle Aged; Recurrence; T-Lymphocyte Subsets; T-Lymphocytes, Regulatory; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta | 2009 |
The anti-inflammatory effects of a methanolic extract from Radix Isatidis in murine macrophages and mice.
Topics: Animals; Anti-Inflammatory Agents; Brassicaceae; Cell Line; Cell Survival; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Ear; Edema; Female; I-kappa B Kinase; Inflammation; Inflammation Mediators; Interleukin-6; Lipopolysaccharides; Macrophages; Methanol; Mice; Mice, Inbred ICR; NF-kappa B; Nitric Oxide; Peroxidase; Plant Extracts; Plant Roots; Solvents; Tetradecanoylphorbol Acetate; Time Factors; Tumor Necrosis Factor-alpha | 2010 |
Diminished macrophage apoptosis and reactive oxygen species generation after phorbol ester stimulation in Crohn's disease.
Topics: Apoptosis; Cell Survival; Crohn Disease; Diglycerides; Endoplasmic Reticulum; Gastrointestinal Tract; Humans; Inflammation; Interleukin-6; Macrophages; Membrane Potentials; Phorbol Esters; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53 | 2009 |
The effects of ambient particulate matter on human alveolar macrophage oxidative and inflammatory responses.
Topics: Adolescent; Adult; Air Pollution; Cytokines; Humans; Inflammation; Interleukin-6; Interleukin-8; Lipopolysaccharides; Macrophages, Alveolar; Oxygen; Particulate Matter; Superoxides; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Vehicle Emissions; Young Adult | 2010 |
Transglutaminase II interacts with rac1, regulates production of reactive oxygen species, expression of snail, secretion of Th2 cytokines and mediates in vitro and in vivo allergic inflammation.
Topics: Anaphylaxis; Animals; Antigens; Cadherins; Carcinogens; Cell Line, Tumor; Cytokines; Dermatitis, Atopic; Dinoprostone; GTP-Binding Proteins; Histone Deacetylases; Inflammation; Intramolecular Oxidoreductases; Matrix Metalloproteinase 2; Mice; Mice, Inbred BALB C; Neuropeptides; NF-kappa B; Prostaglandin-E Synthases; Protein Glutamine gamma Glutamyltransferase 2; rac GTP-Binding Proteins; rac1 GTP-Binding Protein; Rats; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Th2 Cells; Transcription, Genetic; Transglutaminases | 2010 |
Assay systems for measurement of anti-inflammatory activity.
Topics: Animals; Anti-Inflammatory Agents; Antimicrobial Cationic Peptides; Dermatitis, Allergic Contact; Dermatitis, Irritant; Disease Models, Animal; Female; Humans; Inflammation; Mice; Oxazolone; Tetradecanoylphorbol Acetate | 2010 |
T-cell recruitment and Th1 polarization in adipose tissue during diet-induced obesity in C57BL/6 mice.
Topics: Adipose Tissue; Animals; CD11c Antigen; CD3 Complex; CD8-Positive T-Lymphocytes; Chemokine CCL5; Dietary Fats; Gene Expression; Inflammation; Insulin Resistance; Interferon-gamma; Interleukin-12 Subunit p40; Lymphocyte Activation; Macrophages; Male; Mice; Mice, Inbred C57BL; Obesity; T-Lymphocytes; Tetradecanoylphorbol Acetate; Th1 Cells | 2010 |
Regulation of the autophagic machinery in human neutrophils.
Topics: Adenine; Autophagy; Cadaverine; Chromones; Coloring Agents; Escherichia coli; Guanosine; Humans; Hydrogen-Ion Concentration; Inflammation; Microscopy, Confocal; Morpholines; Neutrophils; Phagosomes; Poly I-C; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Sirolimus; Small Ubiquitin-Related Modifier Proteins; Tetradecanoylphorbol Acetate; Toll-Like Receptors; Transcription, Genetic; Vacuoles | 2010 |
Butrin, isobutrin, and butein from medicinal plant Butea monosperma selectively inhibit nuclear factor-kappaB in activated human mast cells: suppression of tumor necrosis factor-alpha, interleukin (IL)-6, and IL-8.
Topics: Butea; Calcimycin; Chalcones; Chromatography, Thin Layer; Enzyme-Linked Immunosorbent Assay; Flavonoids; Gas Chromatography-Mass Spectrometry; Gene Expression; Humans; I-kappa B Kinase; Inflammation; Interleukin-6; Interleukin-8; Mast Cells; NF-kappa B; Plant Extracts; Plants, Medicinal; Polymerase Chain Reaction; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2010 |
Different activities of Schinus areira L.: anti-inflammatory or pro-inflammatory effect.
Topics: Anacardiaceae; Animals; Anti-Inflammatory Agents; Blood; Carrageenan; Cell Survival; Ear; Edema; Female; Foot; Inflammation; Inflammation Mediators; Interleukin-10; Interleukin-6; Macrophages, Peritoneal; Male; Mice; Mice, Inbred Strains; Plant Components, Aerial; Plant Extracts; Respiratory Burst; Superoxides; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Zymosan | 2010 |
Inhibitory effect of the flowers of artichoke (Cynara cardunculus) on TPA-induced inflammation and tumor promotion in two-stage carcinogenesis in mouse skin.
Topics: Acetates; Alcohols; Animals; Anti-Inflammatory Agents; Cynara scolymus; Female; Flowers; Inflammation; Mice; Mice, Inbred ICR; Skin Neoplasms; Tetradecanoylphorbol Acetate; Triterpenes | 2010 |
Genetic heterogeneity of inflammatory response and skin tumorigenesis in phenotypically selected mouse lines.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Genetic Drift; Genetic Heterogeneity; Genetic Predisposition to Disease; Genome-Wide Association Study; Inflammation; Mice; Neutrophil Infiltration; Papilloma; Phenotype; Polymorphism, Single Nucleotide; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2010 |
Phagocytotic competence of differentiated U937 cells for colloidal drug delivery systems in immune cells.
Topics: Anti-Inflammatory Agents; Cell Line, Tumor; Colloids; Drug Delivery Systems; Flow Cytometry; Gene Expression; Humans; Inflammation; Lipopolysaccharide Receptors; Microscopy, Confocal; Monocytes; Nanoparticles; Phagocytosis; Phosphatidylserines; Signal Transduction; Silicon Dioxide; Tetradecanoylphorbol Acetate; U937 Cells | 2011 |
Shikonin reduces oedema induced by phorbol ester by interfering with IkappaBalpha degradation thus inhibiting translocation of NF-kappaB to the nucleus.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Cell Nucleus; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Female; I-kappa B Proteins; Inflammation; Inhibitory Concentration 50; Macrophages; Mice; Naphthoquinones; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; Protein Transport; Tetradecanoylphorbol Acetate | 2010 |
Differential cytokine regulation by NF-kappaB and AP-1 in Jurkat T-cells.
Topics: Adaptor Proteins, Signal Transducing; B-Cell CLL-Lymphoma 10 Protein; Cytokines; Down-Regulation; Escherichia coli; Humans; Inflammation; Interleukin-6; Interleukin-8; JNK Mitogen-Activated Protein Kinases; Jurkat Cells; NF-kappa B; Protein Kinase C; Protein Processing, Post-Translational; T-Lymphocytes; Tetradecanoylphorbol Acetate; Time Factors; Transcription Factor AP-1; Up-Regulation | 2010 |
3,3'-diindolylmethane suppresses 12-O-tetradecanoylphorbol-13-acetate-induced inflammation and tumor promotion in mouse skin via the downregulation of inflammatory mediators.
Topics: Animals; Anti-Inflammatory Agents; Anticarcinogenic Agents; Chemokine CXCL5; Cyclooxygenase 2; Ear; Edema; Extracellular Signal-Regulated MAP Kinases; Female; Gene Expression Regulation; I-kappa B Kinase; Indoles; Inflammation; Inflammation Mediators; Interleukin-6; Mice; Mice, Inbred ICR; NF-kappa B; Nitric Oxide Synthase Type II; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2010 |
Non-hematopoietic expression of IDO is integrally required for inflammatory tumor promotion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adaptor Proteins, Signal Transducing; Animals; Bone Marrow; Bone Marrow Transplantation; Carcinogens; Drug Synergism; Humans; Immune Tolerance; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Interferon-gamma; Interleukin-1beta; Keratinocytes; Lipopolysaccharides; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Nerve Tissue Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Escape; Tumor Suppressor Proteins; U937 Cells; Whole-Body Irradiation | 2010 |
Phosphorylated glucosamine inhibits the inflammatory response in LPS-stimulated PMA-differentiated THP-1 cells.
Topics: Anti-Inflammatory Agents; Cell Differentiation; Cell Line; Cell Survival; Cytokines; Enzyme Activation; Gene Expression Regulation; Glucosamine; Inflammation; Lipopolysaccharides; Macrophages; MAP Kinase Signaling System; Phosphorylation; RNA, Messenger; Tetradecanoylphorbol Acetate | 2010 |
Moderate exercise improves leucocyte function and decreases inflammation in diabetes.
Topics: Animals; Apoptosis; C-Reactive Protein; Chemokines, CXC; Creatine Kinase; Cytokines; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Inflammation; Interleukins; L-Lactate Dehydrogenase; Leukocytes; Macrophages, Peritoneal; Male; Necrosis; Neutrophils; Peritoneal Cavity; Physical Conditioning, Animal; Rats; Rats, Wistar; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2010 |
Identification of the Rage-dependent gene regulatory network in a mouse model of skin inflammation.
Topics: Animals; Cluster Analysis; Computational Biology; Disease Models, Animal; E2F Transcription Factors; Gene Expression Profiling; Gene Expression Regulation; Gene Regulatory Networks; Inflammation; Mice; Models, Biological; Promoter Regions, Genetic; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Retinoblastoma Protein; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Skin; Tetradecanoylphorbol Acetate; Time Factors | 2010 |
Loss of tumor progression locus 2 (tpl2) enhances tumorigenesis and inflammation in two-stage skin carcinogenesis.
Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Cytokines; Female; Immunoblotting; Immunohistochemistry; Inflammation; Male; MAP Kinase Kinase Kinases; Mice; Mice, Inbred C57BL; Mice, Transgenic; Proto-Oncogene Proteins; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2011 |
Dual function of MyD88 in RAS signaling and inflammation, leading to mouse and human cell transformation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Cycle; Cell Transformation, Neoplastic; Extracellular Signal-Regulated MAP Kinases; Humans; Inflammation; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Myeloid Differentiation Factor 88; Phosphorylation; ras Proteins; Signal Transduction; Tetradecanoylphorbol Acetate | 2010 |
Expression and functional activity of chemokine receptors in glatiramer acetate-specific T cells isolated from multiple sclerosis patient receiving the drug glatiramer acetate.
Topics: Adult; Blood; CD4-Positive T-Lymphocytes; Cell Movement; Cells, Cultured; Cerebrospinal Fluid; Chemokines; Chemotaxis, Leukocyte; Flow Cytometry; Gene Expression; Glatiramer Acetate; Humans; Inflammation; Ionomycin; Lymphocyte Activation; Male; Multiple Sclerosis, Relapsing-Remitting; Peptides; Receptors, CCR4; Receptors, CCR5; Receptors, CCR6; Receptors, CXCR3; Signal Transduction; Tetradecanoylphorbol Acetate | 2011 |
Synthetic pseudopterosin analogues: A novel class of antiinflammatory drug candidates.
Topics: Animals; Anti-Inflammatory Agents; Catechols; Diterpenes; Galactosides; Glycosides; Inflammation; Mice; Phenalenes; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 2010 |
Suppression of COX-2, IL-1β and TNF-α expression and leukocyte infiltration in inflamed skin by bioactive compounds from Rosmarinus officinalis L.
Topics: Abietanes; Animals; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship, Drug; Fibronectins; Gene Expression; Inflammation; Intercellular Adhesion Molecule-1; Interleukin-1beta; Macrophages; Male; Mice; Mice, Inbred BALB C; Neutrophil Infiltration; Nitric Oxide; Phytotherapy; Plant Extracts; Reverse Transcriptase Polymerase Chain Reaction; Rosmarinus; Skin; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2011 |
FSP1+ fibroblasts promote skin carcinogenesis by maintaining MCP-1-mediated macrophage infiltration and chronic inflammation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Proliferation; Cell Transformation, Neoplastic; Chemokine CCL2; Chronic Disease; Fibroblasts; Humans; Inflammation; Macrophages; Mice; Mice, Inbred BALB C; Mice, Transgenic; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2011 |
A sesquiterpenol extract potently suppresses inflammation in macrophages and mice skin and prevents chronic liver damage in mice through JNK-dependent HO-1 expression.
Topics: Animals; Carbon Tetrachloride; Cryptomeria; Cyclooxygenase 2 Inhibitors; Dermatitis; Dinoprostone; Heme Oxygenase-1; Humans; Inflammation; Interleukin-6; Lipopolysaccharides; Liver Diseases; Macrophages; Mice; Nitric Oxide Synthase Type II; RNA, Messenger; Sesquiterpenes; Silymarin; Skin; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2011 |
Phenethyl isothiocyanate inhibits 12-O-tetradecanoylphorbol-13-acetate-induced inflammatory responses in mouse skin.
Topics: Animals; Cell Line; Cyclooxygenase 2; Dinoprostone; Extracellular Signal-Regulated MAP Kinases; Inflammation; Interleukin-6; Isothiocyanates; Lipopolysaccharides; Male; Mice; Mice, Inbred ICR; NF-kappa B p50 Subunit; Nitric Oxide; Nitric Oxide Synthase Type II; Phosphorylation; Proto-Oncogene Proteins c-akt; Skin; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2011 |
Investigation of anticholinergic and non-steroidal anti-inflammatory prodrugs which reduce chemically induced skin inflammation.
Topics: Acetylcholinesterase; Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemical Warfare Agents; Cholinergic Antagonists; Cholinesterase Inhibitors; Disease Models, Animal; Ear; Female; Humans; Inflammation; Irritants; Mice; Mustard Gas; Prodrugs; Skin; Tetradecanoylphorbol Acetate | 2012 |
Inhibitory effects of chelidonic acid on IL-6 production by blocking NF-κB and caspase-1 in HMC-1 cells.
Topics: Calcimycin; Calcium Ionophores; Carcinogens; Caspase 1; Caspase Inhibitors; Cell Line; Chelidonium; Enzyme Activation; Gene Expression Regulation, Enzymologic; Humans; Inflammation; Interleukin-6; Mast Cells; NF-kappa B; Pyrans; Rhizome; Tetradecanoylphorbol Acetate | 2011 |
Expression of REIC/Dkk-3 in normal and hyperproliferative epidermis.
Topics: Adaptor Proteins, Signal Transducing; Animals; Cell Line, Tumor; Chemokines; Down-Regulation; Embryo, Mammalian; Epidermis; Hair Follicle; Humans; Inflammation; Intercellular Signaling Peptides and Proteins; Keratosis; Male; Mice; Mice, Inbred BALB C; Skin Diseases, Papulosquamous; Skin Neoplasms; Tetradecanoylphorbol Acetate; Wound Healing | 2011 |
Effect of suppressive oligodeoxynucleotides on the development of inflammation-induced papillomas.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Chemokine CCL2; Chemokine CXCL2; Cyclooxygenase 2; Female; Inflammation; Mice; Oligodeoxyribonucleotides; Ornithine Decarboxylase; Papilloma; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2011 |
Anti-inflammatory activity of an alkaloid from Solanum trilobatum on acute and chronic inflammation models.
Topics: Analysis of Variance; Animals; Anti-Inflammatory Agents; Arachidonic Acid; Arthritis, Experimental; Carrageenan; Dose-Response Relationship, Drug; Edema; India; Inflammation; Leukocytes; Neutrophils; Rats; Rats, Wistar; Solanaceous Alkaloids; Solanum; Tetradecanoylphorbol Acetate | 2011 |
Gomisin N has anti-allergic effect and inhibits inflammatory cytokine expression in mouse bone marrow-derived mast cells.
Topics: Animals; Anti-Allergic Agents; Bone Marrow Cells; Calcimycin; Calcium Ionophores; Carcinogens; Cells, Cultured; Cyclooctanes; Gene Expression Regulation; Hypersensitivity; Inflammation; Inflammation Mediators; Interleukin-6; Lignans; Male; Mast Cells; Mice; Mice, Inbred BALB C; Polycyclic Compounds; Tetradecanoylphorbol Acetate | 2011 |
Tumor necrosis factor-alpha-nuclear factor-kappa B-signaling enhances St2b2 expression during 12-O-tetradecanoylphorbol-13-acetate-induced epidermal hyperplasia.
Topics: Animals; Antibodies; Cholesterol Esters; Epidermis; Female; Hyperplasia; Inflammation; Mice; Mice, Inbred Strains; NF-kappa B; Nitriles; Protein Precursors; Receptors, Tumor Necrosis Factor; RNA, Small Interfering; Signal Transduction; Skin Neoplasms; Sulfones; Sulfotransferases; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2011 |
Electrophilic fatty acids regulate matrix metalloproteinase activity and expression.
Topics: Animals; Carcinogens; Cell Line; Enzyme Activation; Enzyme Precursors; Gene Expression Regulation, Enzymologic; Humans; Hypoglycemic Agents; Inflammation; Matrix Metalloproteinase 9; Metalloendopeptidases; Mice; Mice, Knockout; Oleic Acids; PPAR gamma; Protein Structure, Tertiary; Rosiglitazone; Tetradecanoylphorbol Acetate; Thiazolidinediones; Transcription, Genetic | 2011 |
Thymic stromal lymphopoietin is expressed and produced by caspase-1/NF-κB pathway in mast cells.
Topics: Calcimycin; Caspase 1; Cell Line; Cytokines; Gene Expression Regulation; Humans; Inflammation; Ionophores; Mast Cells; NF-kappa B; RNA, Messenger; Tetradecanoylphorbol Acetate; Thymic Stromal Lymphopoietin; Time Factors | 2011 |
The anti-inflammatory effect of the SOCC blocker SK&F 96365 on mouse lymphocytes after stimulation by Con A or PMA/ionomycin.
Topics: Animals; Anti-Inflammatory Agents; Antigens, CD; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Cycle; Cell Proliferation; Cells, Cultured; Concanavalin A; Cytokines; Dose-Response Relationship, Drug; Female; Fluoresceins; Fluorescent Dyes; Imidazoles; Inflammation; Ionomycin; Lymphocyte Activation; Lymphocyte Count; Membrane Potential, Mitochondrial; Mice; Mice, Inbred BALB C; Mitochondria; Signal Transduction; Succinimides; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thapsigargin | 2011 |
Neutrophil activation is attenuated by high-density lipoprotein and apolipoprotein A-I in in vitro and in vivo models of inflammation.
Topics: Animals; Apolipoprotein A-I; CD11b Antigen; Cell Adhesion; Cell Movement; Cholesterol; Humans; Inflammation; Lipoproteins, HDL; Male; Membrane Microdomains; Mice; Mice, Inbred C57BL; Neutrophil Activation; Peripheral Vascular Diseases; Scavenger Receptors, Class B; Tetradecanoylphorbol Acetate | 2011 |
Embelin reduces cutaneous TNF-α level and ameliorates skin edema in acute and chronic model of skin inflammation in mice.
Topics: Acute Disease; Adult; Animals; Benzoquinones; Chronic Disease; Cytokines; Disease Models, Animal; Ear Diseases; Edema; Female; Humans; Inflammation; Keratinocytes; Lipopolysaccharides; Mice; Mice, Inbred BALB C; Skin Diseases; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2011 |
Anti-inflammatory, antioxidant and antifungal activity of Chuquiraga spinosa.
Topics: Animals; Anti-Inflammatory Agents; Antifungal Agents; Antioxidants; Asteraceae; Candida albicans; Carrageenan; Cladosporium; Disease Models, Animal; Drug Evaluation, Preclinical; Flavonoids; Inflammation; Male; Medicine, Traditional; Methanol; Mice; Peru; Phenols; Phytotherapy; Plant Components, Aerial; Plant Extracts; Polyphenols; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate; Water | 2011 |
Endocannabinoids inhibit release of nerve growth factor by inflammation-activated mast cells.
Topics: Cannabinoid Receptor Modulators; Cell Line, Tumor; Cells, Cultured; Dose-Response Relationship, Drug; Endocannabinoids; Humans; Inflammation; Mast Cells; Nerve Growth Factor; Receptors, Cannabinoid; Receptors, G-Protein-Coupled; Tetradecanoylphorbol Acetate | 2011 |
Inflammation-induced loss of Pdcd4 is mediated by phosphorylation-dependent degradation.
Topics: Animals; Apoptosis Regulatory Proteins; Blotting, Western; Breast Neoplasms; Carcinogens; Cell Differentiation; Culture Media, Conditioned; Female; Genes, Tumor Suppressor; Humans; Inflammation; Interleukin-6; Interleukin-8; Macrophages; Mice; Mice, Inbred C57BL; Monocytes; Phosphatidylinositol 3-Kinases; Phosphorylation; Proteasome Endopeptidase Complex; Reverse Transcriptase Polymerase Chain Reaction; RNA-Binding Proteins; RNA, Messenger; RNA, Small Interfering; Signal Transduction; Tetradecanoylphorbol Acetate; TOR Serine-Threonine Kinases; Tumor Microenvironment; Tumor Necrosis Factor-alpha; U937 Cells | 2011 |
Fritillaria ussuriensis extract inhibits the production of inflammatory cytokine and MAPKs in mast cells.
Topics: Administration, Oral; Animals; Anti-Allergic Agents; Calcimycin; Fritillaria; Histamine Release; Hypersensitivity; Inflammation; Interleukin-6; Interleukin-8; Male; Mast Cells; Mitogen-Activated Protein Kinase Kinases; p-Methoxy-N-methylphenethylamine; Passive Cutaneous Anaphylaxis; Phosphorylation; Phytotherapy; Plant Extracts; Plant Roots; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2011 |
Inhibitory effects of vitamin K₃ derivatives on DNA polymerase and inflammatory activity.
Topics: Animals; Anti-Inflammatory Agents; Colitis; Dextran Sulfate; DNA-Directed DNA Polymerase; Enzyme Inhibitors; Female; Humans; Inflammation; Isoenzymes; Lipopolysaccharides; Macrophages, Peritoneal; Male; Mice; Mice, Inbred C57BL; Naphthoquinones; Nucleic Acid Synthesis Inhibitors; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Vitamin K 3 | 2011 |
B1 and B2 kinin receptor participation in hyperproliferative and inflammatory skin processes in mice.
Topics: Administration, Topical; Animals; Cell Proliferation; Dioxoles; Female; Inflammation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Proliferating Cell Nuclear Antigen; Quinolines; Receptor, Bradykinin B1; Receptor, Bradykinin B2; Skin Diseases; Sulfonamides; Tetradecanoylphorbol Acetate | 2011 |
A (99m)Tc-labeled dual-domain cytokine ligand for imaging of inflammation.
Topics: Animals; Humans; Inflammation; Intercellular Signaling Peptides and Proteins; Interleukin 1 Receptor Antagonist Protein; Interleukin-18; Interleukin-1beta; Leukocytes; Ligands; Male; Mice; Molecular Imaging; Organotechnetium Compounds; Rats; Skin Diseases; Tetradecanoylphorbol Acetate; Tomography, Emission-Computed, Single-Photon | 2011 |
Anti-nociceptive and anti-inflammatory activities of (-)-α-bisabolol in rodents.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Inflammation; Male; Mice; Monocyclic Sesquiterpenes; Neutrophils; Pain; Rats; Sesquiterpenes; Tetradecanoylphorbol Acetate | 2011 |
Inhibitory effect of novel 5-O-acyl juglones on mammalian DNA polymerase activity, cancer cell growth and inflammatory response.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Cell Line, Tumor; DNA Polymerase beta; Enzyme Inhibitors; Humans; Inflammation; Lipopolysaccharides; Mice; Naphthoquinones; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2011 |
Anti-inflammatory effect of transduced PEP-1-cyclophilin A in Raw264.7 cells and 12-O-tetradecanoylphorbol-13-acetate-induced mice.
Topics: Animals; Anti-Inflammatory Agents; Blotting, Western; Cell Line; Cyclooxygenase 2; Cyclophilin A; Cytokines; Dinoprostone; Electrophoretic Mobility Shift Assay; Enzyme-Linked Immunosorbent Assay; Inflammation; Macrophages; Male; Mice; Mice, Inbred ICR; Mitogen-Activated Protein Kinases; NF-kappa B; Peptide Hydrolases; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate | 2011 |
Caffeic acid attenuates 12-O-tetradecanoyl-phorbol-13-acetate (TPA)-induced NF-κB and COX-2 expression in mouse skin: abrogation of oxidative stress, inflammatory responses and proinflammatory cytokine production.
Topics: Animals; Biomarkers; Caffeic Acids; Cyclooxygenase 2; Cytokines; Female; Gene Expression Regulation; Glutathione; Inflammation; Mice; NF-kappa B; Skin; Tetradecanoylphorbol Acetate; Xanthine Oxidase | 2012 |
Chlorophyll revisited: anti-inflammatory activities of chlorophyll a and inhibition of expression of TNF-α gene by the same.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Chlorophyll; Chlorophyll A; Chromolaena; Cyclooxygenase 2; Edema; Eupatorium; Formaldehyde; HEK293 Cells; Humans; Inflammation; Lipopolysaccharides; Mice; Moraceae; NF-kappa B; Nitric Oxide Synthase Type II; Pheophytins; Plant Extracts; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2012 |
Angiopoietin-like protein 2 is an important facilitator of inflammatory carcinogenesis and metastasis.
Topics: Angiopoietin-Like Protein 2; Angiopoietin-like Proteins; Angiopoietins; Animals; Carcinogens; Carcinoma, Squamous Cell; Epithelial-Mesenchymal Transition; Female; Gene Expression; Immunoblotting; Immunohistochemistry; Inflammation; Inflammation Mediators; Kaplan-Meier Estimate; Lymph Nodes; Lymphangiogenesis; Male; Mice; Mice, Knockout; Mice, Transgenic; Neoplasm Metastasis; Neovascularization, Pathologic; Reverse Transcriptase Polymerase Chain Reaction; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2011 |
Topical application of marine briarane-type diterpenes effectively inhibits 12-O-tetradecanoylphorbol-13-acetate-induced inflammation and dermatitis in murine skin.
Topics: Administration, Cutaneous; Animals; Cyclooxygenase 2; Dermatitis, Contact; Diterpenes; Edema; Inflammation; Interleukin-6; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase Type II; Skin; Tetradecanoylphorbol Acetate | 2011 |
Effect of silk fibroin peptide derived from silkworm Bombyx mori on the anti-inflammatory effect of Tat-SOD in a mice edema model.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bombyx; Disease Models, Animal; Edema; Fibroins; Gene Products, tat; Humans; Inflammation; Male; Mice; Mice, Inbred ICR; Peptides; Skin; Superoxide Dismutase; Tetradecanoylphorbol Acetate | 2011 |
Loss of the platelet activating factor receptor in mice augments PMA-induced inflammation and cutaneous chemical carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Inflammation; Mice; Mice, Inbred C57BL; Mice, Knockout; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled; Signal Transduction; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2012 |
ER stress activates the NLRP3 inflammasome via an UPR-independent pathway.
Topics: Animals; Carrier Proteins; Cell Differentiation; Cell Line; Endoplasmic Reticulum Stress; Gene Expression; Humans; Inflammasomes; Inflammation; Interleukin-1beta; Lentivirus; Mice; Mice, Knockout; NLR Family, Pyrin Domain-Containing 3 Protein; Potassium; Reactive Oxygen Species; RNA, Small Interfering; Signal Transduction; Tetradecanoylphorbol Acetate; Tunicamycin; Unfolded Protein Response | 2012 |
D-Limonene modulates inflammation, oxidative stress and Ras-ERK pathway to inhibit murine skin tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Carcinogens; Catalase; Cyclohexenes; Cyclooxygenase 2; Female; Glutathione; Inflammation; Limonene; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Oxidative Stress; raf Kinases; ras Proteins; Signal Transduction; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate | 2012 |
Antiinflammatory, analgesic and antioxidant activities of Cyathula prostrata (Linn.) Blume (Amaranthaceae).
Topics: Acetic Acid; Amaranthaceae; Analgesics; Animals; Anti-Inflammatory Agents; Antioxidants; Arachidonic Acid; Behavior, Animal; Biphenyl Compounds; Carrageenan; Cyclooxygenase 2; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Hot Temperature; Humans; Inflammation; Inflammation Mediators; Lipid Peroxidation; Lipopolysaccharides; Macrophages; Male; Methanol; Mice; Motor Activity; Nitric Oxide; Oxidative Stress; Pain; Pain Threshold; Phytotherapy; Picrates; Plant Preparations; Plants, Medicinal; Rats; Rats, Wistar; Reactive Oxygen Species; Solvents; Tetradecanoylphorbol Acetate; U937 Cells; Xylenes | 2012 |
Anti-inflammatory activity of hautriwaic acid isolated from Dodonaea viscosa leaves.
Topics: Animals; Anti-Inflammatory Agents; Disease Models, Animal; Diterpenes; Female; Inflammation; Mice; Plant Extracts; Plant Leaves; Sapindaceae; Tetradecanoylphorbol Acetate | 2012 |
Mediterranean diet polyphenols reduce inflammatory angiogenesis through MMP-9 and COX-2 inhibition in human vascular endothelial cells: a potentially protective mechanism in atherosclerotic vascular disease and cancer.
Topics: Antioxidants; Atherosclerosis; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Diet, Mediterranean; Gene Expression Regulation, Enzymologic; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Neoplasms; Neovascularization, Pathologic; NF-kappa B; Olive Oil; Plant Oils; Polyphenols; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Wine | 2012 |
Potentiation of the P2X3 ATP receptor by PAR-2 in rat dorsal root ganglia neurons, through protein kinase-dependent mechanisms, contributes to inflammatory pain.
Topics: Adenosine Triphosphate; Animals; Carbazoles; Colforsin; Cyclic AMP-Dependent Protein Kinases; Ganglia, Spinal; Indoles; Inflammation; Male; Maleimides; MAP Kinase Signaling System; Membrane Potentials; Neurons; Pain; Phosphorylation; Protein Kinase C; Protein Transport; Purinergic P2X Receptor Agonists; Purinergic P2X Receptor Antagonists; Pyrroles; Rats, Sprague-Dawley; Receptor, PAR-2; Receptors, Purinergic P2X3; Tetradecanoylphorbol Acetate | 2012 |
β-Glucans are involved in immune-modulation of THP-1 macrophages.
Topics: Avena; beta-Glucans; Cell Differentiation; Cell Line, Tumor; Chromatography, Gel; Gene Expression Regulation; Glycoside Hydrolases; Hordeum; Humans; Hydrogen Peroxide; Immunologic Factors; Inflammation; Lipopolysaccharides; Macrophages; Nitric Oxide; Phagocytosis; Plant Extracts; Shiitake Mushrooms; Tetradecanoylphorbol Acetate | 2012 |
MT1-MMP expression level status dictates the in vitro action of lupeol on inflammatory biomarkers MMP-9 and COX-2 in medulloblastoma cells.
Topics: Anti-Inflammatory Agents; Cell Line, Tumor; Child; Cyclooxygenase 2; Drug Synergism; Gene Expression Regulation, Neoplastic; Humans; Inflammation; Matrix Metalloproteinase 14; Matrix Metalloproteinase 9; Medulloblastoma; Pentacyclic Triterpenes; RNA, Messenger; Tetradecanoylphorbol Acetate | 2013 |
Characterization of 99mTc-labeled cytokine ligands for inflammation imaging via TNF and IL-1 pathways.
Topics: Animals; CHO Cells; Cricetinae; Cricetulus; Drug Stability; Edema; Gene Expression Regulation; Inflammation; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Interleukin-1beta; Isotope Labeling; Ligands; Male; Mice; Molecular Imaging; Organotechnetium Compounds; Protein Transport; Rats; Receptors, Tumor Necrosis Factor, Type II; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2012 |
The orphan receptor GPR55 drives skin carcinogenesis and is upregulated in human squamous cell carcinomas.
Topics: Animals; Carcinoma, Squamous Cell; Cell Proliferation; Gene Expression Regulation, Neoplastic; Humans; Inflammation; Laryngeal Neoplasms; Mice; Mice, Knockout; Mouth Neoplasms; Protein Disulfide-Isomerases; Receptors, Cannabinoid; Receptors, G-Protein-Coupled; Reference Values; Skin Neoplasms; Tetradecanoylphorbol Acetate; Up-Regulation | 2013 |
Geraniol inhibits murine skin tumorigenesis by modulating COX-2 expression, Ras-ERK1/2 signaling pathway and apoptosis.
Topics: Acyclic Monoterpenes; Animals; Anticarcinogenic Agents; Apoptosis; bcl-2-Associated X Protein; Carcinogenesis; Cyclooxygenase 2; Edema; Female; Inflammation; MAP Kinase Signaling System; Mice; Oxidative Stress; ras Proteins; Skin; Terpenes; Tetradecanoylphorbol Acetate | 2013 |
7b, a novel amonafide analog, inhibited proliferation and phorbol 12-myristate 13-acetate/phytohemagglutinin-induced inflammatory responses of Jurkat T cells via p73-dependent pathway and decrease of nuclear factor-κB DNA-binding, respectively.
Topics: Anti-Inflammatory Agents; Antineoplastic Agents; Apoptosis; Cell Cycle Checkpoints; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Cytokines; DNA Damage; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; Humans; Inflammation; Inflammation Mediators; Jurkat Cells; Mitochondria; Naphthalimides; NF-kappa B; Nuclear Proteins; Oxidation-Reduction; Phytohemagglutinins; Proto-Oncogene Proteins c-myc; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Tumor Protein p73; Tumor Suppressor Protein p53; Tumor Suppressor Proteins | 2013 |
Collagen XVII (BP180) modulates keratinocyte expression of the proinflammatory chemokine, IL-8.
Topics: Autoantigens; Cell Line; Collagen Type XVII; Epidermolysis Bullosa; Gene Expression Regulation; Humans; Inflammation; Integrin alpha6beta4; Interleukin-18; Keratinocytes; Lipopolysaccharides; NF-kappa B; Non-Fibrillar Collagens; RNA, Small Interfering; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Ultraviolet Rays | 2012 |
Pterostilbene, a natural analogue of resveratrol, potently inhibits 7,12-dimethylbenz[a]anthracene (DMBA)/12-O-tetradecanoylphorbol-13-acetate (TPA)-induced mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents, Phytogenic; Cell Proliferation; Cyclooxygenase 2; Down-Regulation; Female; Inflammation; Mice; Mice, Inbred ICR; NF-kappa B; Nitric Oxide Synthase Type II; Protein Kinase Inhibitors; Resveratrol; Skin; Skin Neoplasms; Stilbenes; Tetradecanoylphorbol Acetate | 2012 |
Anti-inflammatory and anti-ulcer activities of carvacrol, a monoterpene present in the essential oil of oregano.
Topics: Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Arachidonic Acid; Cymenes; Edema; Female; Indomethacin; Inflammation; Male; Mice; Monoterpenes; Oils, Volatile; Origanum; Rats; Rats, Wistar; Ruthenium Red; Stomach Ulcer; Substance P; Tetradecanoylphorbol Acetate | 2012 |
Anti-inflammatory and anti-allergic effect of Agaricus blazei extract in bone marrow-derived mast cells.
Topics: Agaricus; Animals; Anti-Allergic Agents; Anti-Inflammatory Agents; beta-N-Acetylhexosaminidases; Biological Products; Bone Marrow Cells; Calcimycin; Cell Degranulation; Down-Regulation; Female; Inflammation; Interleukin-6; Leukotriene C4; Mast Cells; Mice; Mice, Inbred BALB C; Phosphorylation; Phytotherapy; Prostaglandin D2; Proto-Oncogene Proteins c-akt; Tetradecanoylphorbol Acetate | 2012 |
RAC1 in keratinocytes regulates crosstalk to immune cells by Arp2/3-dependent control of STAT1.
Topics: Abietanes; Actin Cytoskeleton; Actin-Related Protein 2-3 Complex; Actins; Animals; Cell Differentiation; Enzyme Activation; Epidermis; Gene Expression Regulation; Inflammation; Interferon-gamma; Keratinocytes; Leukocytes; Mice; Mice, Inbred C57BL; Mice, Knockout; Neuropeptides; Polymerization; rac GTP-Binding Proteins; rac1 GTP-Binding Protein; Signal Transduction; Skin; STAT1 Transcription Factor; Tetradecanoylphorbol Acetate | 2012 |
Soy isoflavones (daidzein & genistein) inhibit 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced cutaneous inflammation via modulation of COX-2 and NF-κB in Swiss albino mice.
Topics: Animals; Cell Proliferation; Cyclooxygenase 2; Dermatitis; Female; Genistein; Glycine max; Inflammation; Isoflavones; Ki-67 Antigen; Mice; NF-kappa B; Oxidative Stress; Plant Extracts; Skin; Tetradecanoylphorbol Acetate | 2012 |
Tissue-specific opposing functions of the inflammasome adaptor ASC in the regulation of epithelial skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adaptor Proteins, Signal Transducing; Animals; Apoptosis Regulatory Proteins; CARD Signaling Adaptor Proteins; Caspase 1; Cell Proliferation; Cell Transformation, Neoplastic; Cytokines; Cytoskeletal Proteins; Down-Regulation; Epithelium; Humans; Inflammasomes; Inflammation; Keratinocytes; Mice; Mice, Knockout; Myeloid Cells; Neoplasms, Squamous Cell; Organ Specificity; Receptors, Interleukin-1; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Microenvironment; Tumor Suppressor Protein p53 | 2012 |
The role of PKC/ERK1/2 signaling in the anti-inflammatory effect of tetracyclic triterpene euphol on TPA-induced skin inflammation in mice.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2; Edema; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Inflammation; Lanosterol; Leukocytes; Male; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Protein Kinase C; Skin Diseases; Tetradecanoylphorbol Acetate; Up-Regulation | 2013 |
Baicalein inhibits DMBA/TPA-induced skin tumorigenesis in mice by modulating proliferation, apoptosis, and inflammation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Apoptosis; Cell Proliferation; Cell Transformation, Neoplastic; Female; Flavanones; Hyperplasia; Inflammation; Mice; Mice, Inbred C57BL; Plant Extracts; Scutellaria baicalensis; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2013 |
Overexpression of TNF-α-converting enzyme in fibroblasts augments dermal fibrosis after inflammation.
Topics: ADAM Proteins; ADAM17 Protein; Animals; Collagen Type I; ErbB Receptors; Female; Fibroblasts; Fibrosis; Furin; Histocytochemistry; Immune System Phenomena; Inflammation; Mice; Mice, Transgenic; Skin; Tetradecanoylphorbol Acetate | 2013 |
Geraniol attenuates 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced oxidative stress and inflammation in mouse skin: possible role of p38 MAP Kinase and NF-κB.
Topics: Acyclic Monoterpenes; Administration, Topical; Animals; Antioxidants; Cyclooxygenase 2; Cytokines; Edema; Female; Glutathione; Inflammation; Lipid Peroxidation; Mice; NF-kappa B; Oxidative Stress; Oxidoreductases; p38 Mitogen-Activated Protein Kinases; Reactive Oxygen Species; Skin; Terpenes; Tetradecanoylphorbol Acetate | 2013 |
Analgesic and antiinflammatory properties of Sideritis lotsyi var. Mascaensis.
Topics: Acetic Acid; Analgesics; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Bacteria; Carrageenan; Dose-Response Relationship, Drug; Ear, External; Female; Hindlimb; Inflammation; Male; Mice; Phytotherapy; Plant Extracts; Sideritis; Tetradecanoylphorbol Acetate; Toxicity Tests, Acute | 2002 |
Specific up-regulation of CRH or AVP secretion by acetylcholine or lipopolysaccharide in inflammatory susceptible Lewis rat fetal hypothalamic cells.
Topics: Acetylcholine; Animals; Arginine Vasopressin; Cells, Cultured; Colforsin; Corticotropin-Releasing Hormone; Dose-Response Relationship, Drug; Hypothalamus; Inflammation; Interleukin-1; Interleukin-6; Lipopolysaccharides; Rats; Rats, Inbred F344; Rats, Inbred Lew; Serotonin; Species Specificity; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Up-Regulation | 2002 |
A new dual inhibitor of arachidonate metabolism isolated from Helichrysum italicum.
Topics: Acetophenones; Analgesics; Animals; Arachidonic Acid; Carrageenan; Dose-Response Relationship, Drug; Ear; Edema; Female; Free Radicals; Glucosides; Helichrysum; Hindlimb; Inflammation; Leukotriene B4; Lipid Peroxidation; Mice; Neutrophils; Peroxidase; Phospholipases A; Plant Extracts; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate | 2003 |
[Relationship between complement activation and reactive oxygen species generation in inflammatory response].
Topics: Animals; Cell Separation; Complement Activation; Cricetinae; Inflammation; Inulin; Neutrophils; Reactive Oxygen Species; Tetradecanoylphorbol Acetate | 1999 |
Modulation of PECAM-1 expression and alternative splicing during differentiation and activation of hematopoietic cells.
Topics: Alternative Splicing; Amino Acid Sequence; Base Sequence; Cell Differentiation; Gene Expression Regulation; Hematopoiesis; Hematopoietic Stem Cells; Humans; Inflammation; Jurkat Cells; Molecular Sequence Data; Platelet Endothelial Cell Adhesion Molecule-1; Protein Isoforms; RNA; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2003 |
Inflammatory agonist stimulation and signal pathway of oxidative burst in neonatal chicken heterophils.
Topics: Animals; Animals, Newborn; Chickens; Enzyme Inhibitors; Flavonoids; Fluoresceins; Imidazoles; Inflammation; Lipopolysaccharides; Male; Mitogen-Activated Protein Kinases; Neutrophils; Protein Kinase C; Pyridines; Respiratory Burst; Salmonella enteritidis; Signal Transduction; Staphylococcus aureus; Teichoic Acids; Tetradecanoylphorbol Acetate | 2003 |
Transforming growth factor-beta 1 increases glucocorticoid binding and signaling in macrophages through a Smad- and activated protein-1-mediated process.
Topics: Carcinogens; Cell Differentiation; DNA-Binding Proteins; Gene Expression; Glucocorticoids; Humans; Inflammation; Interleukin-8; Macrophages; Protein Binding; Receptors, Glucocorticoid; Signal Transduction; Smad2 Protein; Smad3 Protein; Tetradecanoylphorbol Acetate; Trans-Activators; Transcription Factor AP-1; Transcription, Genetic; Transforming Growth Factor beta; Transforming Growth Factor beta1; U937 Cells; Up-Regulation | 2003 |
Targeting apoptotic signalling pathway and pro-inflammatory cytokine expression as therapeutic intervention in TPE induced lung damage.
Topics: Cell Line; Cytokines; Dose-Response Relationship, Drug; Drug Delivery Systems; Gene Expression Regulation; Glycoproteins; Humans; Hydrocortisone; Inflammation; Lung; Pulmonary Eosinophilia; Signal Transduction; Tetradecanoylphorbol Acetate | 2003 |
Effects of wogonin, a plant flavone from Scutellaria radix, on skin inflammation: in vivo regulation of inflammation-associated gene expression.
Topics: Animals; Arachidonic Acid; Dermatitis; Drugs, Chinese Herbal; Flavanones; Flavonoids; Gene Expression; Inflammation; Male; Mice; Mice, Inbred ICR; Plant Extracts; Scutellaria baicalensis; Tetradecanoylphorbol Acetate | 2003 |
Myrsinoic acid E, an anti-inflammatory compound from Myrsine seguinii.
Topics: Alkenes; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzoates; Inflammation; Mice; Parabens; Primulaceae; Terpenes; Tetradecanoylphorbol Acetate | 2003 |
Some anti-chronic inflammatory compounds are DNA polymerase lambda-specific inhibitors.
Topics: Animals; Anti-Inflammatory Agents; Caffeic Acids; Cell Division; Curcumin; DNA Polymerase beta; Enzyme Inhibitors; Humans; Inflammation; Mice; Phenols; Tetradecanoylphorbol Acetate | 2003 |
Evidence for ozone formation in human atherosclerotic arteries.
Topics: Arteriosclerosis; Carotid Arteries; Cholestanes; Cholesterol; Dimethyl Sulfoxide; Endarterectomy, Carotid; Foam Cells; Humans; Hydrazones; Indigo Carmine; Inflammation; Leukocytes; Lipoproteins, LDL; Norsteroids; Oxidation-Reduction; Ozone; Singlet Oxygen; Sterols; Tetradecanoylphorbol Acetate | 2003 |
Induction of distinct sets of secretory phospholipase A(2) in rodents during inflammation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Base Sequence; Chromans; Edema; Enzyme Induction; Enzyme Inhibitors; Exons; Gene Expression Regulation, Enzymologic; Group II Phospholipases A2; Humans; Indomethacin; Inflammation; Lipopolysaccharides; Mice; Molecular Sequence Data; Mutagenesis, Insertional; Phenols; Phospholipases A; Rats; Recombinant Proteins; Tetradecanoylphorbol Acetate; Transfection | 2003 |
Effects of different dietary oils on inflammatory mediator generation and fatty acid composition in rat neutrophils.
Topics: Animals; Arachidonic Acid; Calcimycin; Dietary Fats, Unsaturated; Dinoprostone; Eicosanoids; Fatty Acids; Fatty Acids, Essential; Fish Oils; gamma-Linolenic Acid; Glucuronidase; Glycogen; Hydrogen Peroxide; Inflammation; Linoleic Acid; Linoleic Acids; Lysosomes; Male; Muramidase; Neutrophils; Oenothera biennis; Oleic Acid; Olive Oil; Peritoneum; Peroxidase; Plant Oils; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxides; Tetradecanoylphorbol Acetate; Thromboxane B2 | 2004 |
Benzyl isothiocyanate inhibits excessive superoxide generation in inflammatory leukocytes: implication for prevention against inflammation-related carcinogenesis.
Topics: Anticarcinogenic Agents; Cell Differentiation; Glutathione; HL-60 Cells; Humans; Inflammation; Isothiocyanates; Kinetics; Leukocytes; NADPH Oxidases; Neoplasms; Protein Kinase C; Protein Transport; Superoxides; Tetradecanoylphorbol Acetate | 2004 |
Pro/antioxidant status in murine skin following topical exposure to cumene hydroperoxide throughout the ontogeny of skin cancer.
Topics: Animals; Antioxidants; Benzene Derivatives; Cell Line, Tumor; Cyclooxygenase 2; Dinoprostone; Enzyme Inhibitors; Female; Glutathione; Humans; Inflammation; Isoenzymes; Keratinocytes; Lipid Peroxidation; Membrane Proteins; Mice; Mice, Inbred SENCAR; Oxidative Stress; Prostaglandin-Endoperoxide Synthases; Skin Neoplasms; Sulfhydryl Compounds; Tetradecanoylphorbol Acetate | 2004 |
Differential effect of phosphodiesterase IV inhibitor RP73401 on various inflammatory and immune responses relevent to rheumatoid arthritis.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Arachidonic Acid; Arthritis, Experimental; Arthritis, Rheumatoid; Benzamides; Cell Physiological Phenomena; Cyclic Nucleotide Phosphodiesterases, Type 4; Disease Models, Animal; Drug Evaluation, Preclinical; Ear Diseases; Edema; Humans; Immunity, Active; Inflammation; Lipopolysaccharides; Lymphocytes; Male; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Nitric Oxide; Pyridines; Rats; Rats, Sprague-Dawley; Spleen; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; U937 Cells | 2004 |
Anti-inflammatory agents from Sandoricum koetjape Merr.
Topics: Animals; Anti-Inflammatory Agents; Female; Inflammation; Meliaceae; Mice; Mice, Inbred BALB C; Phytotherapy; Plant Extracts; Plant Stems; Tetradecanoylphorbol Acetate | 2004 |
Crosstalk between PARP-1 and NF-kappaB modulates the promotion of skin neoplasia.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Binding Sites; Carcinogens; Cell Division; Disease Progression; Enzyme Activation; Epidermis; Epithelium; Inflammation; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Fluorescence; Mitosis; NF-kappa B; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Poly(ADP-ribose) Polymerases; Promoter Regions, Genetic; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 2004 |
Requirement of Hsp90 activity for IkappaB kinase (IKK) biosynthesis and for constitutive and inducible IKK and NF-kappaB activation.
Topics: Animals; Benzoquinones; Cell Line; Cell Line, Tumor; COS Cells; Dose-Response Relationship, Drug; Enzyme Inhibitors; HeLa Cells; HSP90 Heat-Shock Proteins; Humans; I-kappa B Kinase; Inflammation; Interleukin-1; Lactams, Macrocyclic; Lactones; Lymphoma; Macrolides; Molecular Chaperones; NF-kappa B; Phosphorylation; Precipitin Tests; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Quinones; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors; Transfection; Tumor Necrosis Factor-alpha; Ubiquitin | 2004 |
Effects of the Geiji-Bokryung-Hwan on carrageenan-induced inflammation in mice and cyclooxygenase-2 in hepatoma cells of HepG2 and Hep3B.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carcinoma, Hepatocellular; Carrageenan; Cell Line, Tumor; Cyclooxygenase 2; Dinoprostone; Edema; Female; Hindlimb; Humans; Hydroquinones; Indomethacin; Inflammation; Isoenzymes; Liver Neoplasms; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Phenylbutazone; Plant Extracts; Prostaglandin-Endoperoxide Synthases; Protein-Tyrosine Kinases; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tyrphostins | 2004 |
Anti-inflammatory effects of tacalcitol (1,24(R)(OH)2D3, TV-02) in the skin of TPA-treated hairless mice.
Topics: Administration, Cutaneous; Animals; Anti-Inflammatory Agents; Base Sequence; Dermatitis; Dihydroxycholecalciferols; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Immunohistochemistry; Inflammation; Inflammation Mediators; Mast Cells; Mice; Mice, Hairless; Molecular Sequence Data; Neutrophil Infiltration; Peroxidase; Random Allocation; Reverse Transcriptase Polymerase Chain Reaction; Tetradecanoylphorbol Acetate | 2004 |
Human T lymphocytes and mast cells differentially express and regulate extra- and intracellular CXCR1 and CXCR2.
Topics: Actins; Calcium; Cell Line; Cell Membrane; Cell Movement; Down-Regulation; Flow Cytometry; Gene Expression Regulation; Glycosylation; Humans; Immunoblotting; Inflammation; Interleukin-8; Ionophores; Kinetics; Receptors, Interleukin-8A; Receptors, Interleukin-8B; T-Lymphocytes; Tetradecanoylphorbol Acetate; Time Factors | 2004 |
The differential effects of IL-1 and TNF-alpha on proinflammatory cytokine and matrix metalloproteinase expression in human chondrosarcoma cells.
Topics: Cell Line, Tumor; Chondrosarcoma; Cluster Analysis; Cytokines; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Inflammation; Inflammation Mediators; Interleukin-1; Matrix Metalloproteinases; Oligonucleotide Array Sequence Analysis; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Tetradecanoylphorbol Acetate; Time Factors; Tumor Necrosis Factor-alpha | 2004 |
Guggulsterone inhibits NF-kappaB and IkappaBalpha kinase activation, suppresses expression of anti-apoptotic gene products, and enhances apoptosis.
Topics: Active Transport, Cell Nucleus; Apoptosis; Blotting, Western; Cell Line; Cell Line, Tumor; Cyclooxygenase 2; Dose-Response Relationship, Drug; Enzyme Activation; Gene Expression Regulation; Genes, Reporter; Humans; I-kappa B Proteins; Inflammation; Interleukin-1; Isoenzymes; Jurkat Cells; Luciferases; Membrane Proteins; Models, Chemical; Neoplasm Metastasis; NF-kappa B; NF-KappaB Inhibitor alpha; Okadaic Acid; Phosphorylation; Poly(ADP-ribose) Polymerases; Pregnenediones; Promoter Regions, Genetic; Prostaglandin-Endoperoxide Synthases; Protein Structure, Tertiary; Temperature; Tetradecanoylphorbol Acetate; Transcription, Genetic | 2004 |
Chemiluminescence: comparison of whole blood with isolated polymorphonuclear leukocytes after major trauma.
Topics: Case-Control Studies; Cell Separation; Disease Progression; Humans; Inflammation; Injury Severity Score; Luminescent Measurements; Macrophage-1 Antigen; Multiple Organ Failure; Multiple Trauma; NADP; Neutrophil Activation; Neutrophils; Patient Selection; Predictive Value of Tests; Reactive Oxygen Species; Respiratory Burst; Respiratory Distress Syndrome; Risk Factors; Statistics, Nonparametric; Tetradecanoylphorbol Acetate; Time Factors; Zymosan | 2004 |
Methionine-enkephalin stimulates hydrogen peroxide and nitric oxide production in rat peritoneal macrophages: interaction of mu, delta and kappa opioid receptors.
Topics: Animals; Dose-Response Relationship, Drug; Enkephalin, Methionine; Hydrogen Peroxide; Inflammation; Lipopolysaccharides; Macrophages, Peritoneal; Male; Narcotic Antagonists; Neuroimmunomodulation; Nitric Oxide; Rats; Rats, Wistar; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Tetradecanoylphorbol Acetate; Up-Regulation | 2004 |
The junctional adhesion molecule-C promotes neutrophil transendothelial migration in vitro and in vivo.
Topics: Animals; Blotting, Western; Cell Adhesion; Cell Adhesion Molecules; Cell Movement; Cells, Cultured; Endothelial Cells; Endothelium, Vascular; Flow Cytometry; Humans; Immunoblotting; Immunoglobulins; In Vitro Techniques; Inflammation; Junctional Adhesion Molecules; Membrane Proteins; Mice; Microscopy, Fluorescence; Neutrophils; Peritonitis; Phosphoproteins; Protein Binding; Tetradecanoylphorbol Acetate; Zonula Occludens-1 Protein | 2004 |
Histamine reduces gap junctional communication of human tonsil high endothelial cells in culture.
Topics: Cells, Cultured; Chlorpheniramine; Coloring Agents; Connexin 43; Cyclic AMP; Cyclooxygenase Inhibitors; Cytoskeleton; Dose-Response Relationship, Drug; Endothelial Cells; Enzyme Inhibitors; Gap Junctions; Histamine; Humans; Immunoblotting; Indoles; Indomethacin; Inflammation; Ionophores; Maleimides; Microscopy, Fluorescence; Palatine Tonsil; Phalloidine; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate; Time Factors | 2004 |
Smad3 knockout mice exhibit a resistance to skin chemical carcinogenesis.
Topics: Animals; Apoptosis; Disease Susceptibility; DNA-Binding Proteins; Epidermis; Female; Inflammation; Keratinocytes; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Skin Neoplasms; Smad3 Protein; Tetradecanoylphorbol Acetate; Trans-Activators; Transcription Factor AP-1; Transforming Growth Factor alpha | 2004 |
Effects of COX-2 inhibitors on ROS produced by Chlamydia pneumoniae-primed human promonocytic cells (THP-1).
Topics: Arteriosclerosis; Cell Differentiation; Cell Line; Chlamydophila pneumoniae; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Free Radicals; Humans; Inflammation; Macrophages; Monocytes; Reactive Oxygen Species; Tetradecanoylphorbol Acetate | 2004 |
Moraxella catarrhalis--infected alveolar epithelium induced monocyte recruitment and oxidative burst.
Topics: Carcinogens; Cell Adhesion; Cell Adhesion Molecules; Cell Line; Cell Movement; Cytokines; Epithelium; Humans; Indoles; Inflammation; Lipopolysaccharides; Lung Diseases; Macrophage Activation; Maleimides; Monocytes; Moraxella catarrhalis; Moraxellaceae Infections; Protein Kinase C; Pulmonary Alveoli; Respiratory Burst; Superoxides; Tetradecanoylphorbol Acetate | 2005 |
Analgesic and topical anti-inflammatory activity of Hypericum canariense L. and Hypericum glandulosum Ait.
Topics: Acetic Acid; Administration, Oral; Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Ear; Female; Flowers; Hypericum; Inflammation; Male; Mice; Pain; Phytotherapy; Plant Extracts; Tail; Tetradecanoylphorbol Acetate | 2005 |
Benzyl isothiocyanate inhibits oxidative stress in mouse skin: Involvement of attenuation of leukocyte infiltration.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Chemotaxis, Leukocyte; Hydrogen Peroxide; Inflammation; Isothiocyanates; Mice; Oxidative Stress; Skin; Skin Physiological Phenomena; Tetradecanoylphorbol Acetate | 2004 |
Evidence for the involvement of the cannabinoid CB2 receptor and its endogenous ligand 2-arachidonoylglycerol in 12-O-tetradecanoylphorbol-13-acetate-induced acute inflammation in mouse ear.
Topics: Administration, Topical; Animals; Arachidonic Acids; Camphanes; Cannabinoid Receptor Modulators; Dose-Response Relationship, Drug; Ear; Endocannabinoids; Glycerides; Inflammation; Ligands; Male; Mice; Mice, Inbred ICR; Pyrazoles; Receptor, Cannabinoid, CB2; Tetradecanoylphorbol Acetate | 2005 |
Protein kinase C-dependent regulation of NAG-1/placental bone morphogenic protein/MIC-1 expression in LNCaP prostate carcinoma cells.
Topics: Apoptosis; Blotting, Northern; Blotting, Western; Carcinogens; Cell Line, Tumor; Cell Nucleus; Cell Survival; Chromatin Immunoprecipitation; Cytokines; Dose-Response Relationship, Drug; Gene Expression Regulation; Growth Differentiation Factor 15; Humans; Inflammation; JNK Mitogen-Activated Protein Kinases; Luciferases; Male; MAP Kinase Kinase 4; MAP Kinase Kinase Kinase 1; Mitogen-Activated Protein Kinase Kinases; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Promoter Regions, Genetic; Prostatic Neoplasms; Protein Isoforms; Protein Kinase C; RNA, Messenger; RNA, Small Interfering; Tetradecanoylphorbol Acetate; Time Factors; Transcription, Genetic; Transfection | 2005 |
Structural analysis of epolactaene derivatives as DNA polymerase inhibitors and anti-inflammatory compounds.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Epoxy Compounds; Inflammation; Mice; Models, Molecular; Molecular Conformation; Nucleic Acid Synthesis Inhibitors; Polyenes; Tetradecanoylphorbol Acetate; Topoisomerase II Inhibitors | 2005 |
Comparison of respiratory burst activity of inflammatory neutrophils in ayu (Plecoglossus altivelis) and carp (Cyprinus carpio).
Topics: Animals; Carps; Fish Diseases; Flow Cytometry; Inflammation; Kidney; Luminescent Measurements; Neutrophils; Respiratory Burst; Salmoniformes; Tetradecanoylphorbol Acetate; Zymosan | 2005 |
Primed peripheral polymorphonuclear leukocyte: a culprit underlying chronic low-grade inflammation and systemic oxidative stress in chronic kidney disease.
Topics: Adult; Albumins; Apoptosis; C-Reactive Protein; Case-Control Studies; Cell Survival; Female; Glomerular Filtration Rate; Humans; Inflammation; Interleukin-6; Kidney Failure, Chronic; Leukocytes, Mononuclear; Male; Middle Aged; Neutrophils; Oxidative Stress; Peritoneal Dialysis, Continuous Ambulatory; Peroxidase; Renal Insufficiency; Superoxides; Temperature; Tetradecanoylphorbol Acetate; Time Factors | 2005 |
Role of glucoxidation and lipid oxidation in the development of atherosclerosis.
Topics: Arteriosclerosis; Cell Line; Glucose; Humans; Inflammation; Lipid Peroxidation; Lysine; Monocytes; Oxidation-Reduction; Oxidative Stress; Protein Kinase C; Ribonucleases; Tetradecanoylphorbol Acetate; Wound Healing | 2005 |
Production of modified C-reactive protein in U937-derived macrophages.
Topics: Acute-Phase Reaction; Antibodies, Monoclonal; Arteriosclerosis; C-Reactive Protein; Cell Differentiation; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Fluorescent Antibody Technique; Humans; Inflammation; Kinetics; Lipopolysaccharides; Macrophages; Microscopy, Fluorescence; Protein Isoforms; Reverse Transcriptase Polymerase Chain Reaction; Tetradecanoylphorbol Acetate; Time Factors; U937 Cells | 2005 |
Inhibitory effects of black tea theaflavin derivatives on 12-O-tetradecanoylphorbol-13-acetate-induced inflammation and arachidonic acid metabolism in mouse ears.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Biflavonoids; Catechin; Dinoprostone; Drug Synergism; Ear; Edema; Female; Gallic Acid; Inflammation; Interleukin-1; Interleukin-6; Leukotriene B4; Lipoxygenase; Mice; Prostaglandin-Endoperoxide Synthases; Sulindac; Tea; Tetradecanoylphorbol Acetate | 2006 |
Anti-inflammatory activity of 5-O-demethylnobiletin, a polymethoxyflavone isolated from Sideritis tragoriganum.
Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Cells, Cultured; Ear; Female; Flavones; Humans; Inflammation; Mice; Neutrophils; Phospholipases A; Rats; Rats, Wistar; Sideritis; Tetradecanoylphorbol Acetate | 2006 |
Co-localization of COX-2, CYP4F8, and mPGES-1 in epidermis with prominent expression of CYP4F8 mRNA in psoriatic lesions.
Topics: Aryl Hydrocarbon Hydroxylases; Carcinogens; Cell Line; Cyclooxygenase 2; Cytokines; Epidermis; Gene Expression Regulation, Enzymologic; Humans; Inflammation; Intramolecular Oxidoreductases; Keratinocytes; Membrane Proteins; Prostaglandin-E Synthases; Psoriasis; RNA, Messenger; Tetradecanoylphorbol Acetate | 2006 |
Evaluation of the analgesic and topical anti-inflammatory effects of Hypericum reflexum L. fil.
Topics: Administration, Oral; Analgesics; Animals; Anti-Inflammatory Agents; Hypericum; Inflammation; Mice; Plant Extracts; Tetradecanoylphorbol Acetate | 2006 |
Overexpression of the prostaglandin E2 receptor EP2 results in enhanced skin tumor development.
Topics: Animals; Animals, Newborn; Bromodeoxyuridine; Carcinoma, Squamous Cell; Cattle; Cell Culture Techniques; Cell Proliferation; Female; Humans; Hyperplasia; Inflammation; Keratinocytes; Keratins; Mice; Mice, Transgenic; Neovascularization, Pathologic; Polymerase Chain Reaction; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Skin Neoplasms; Tetradecanoylphorbol Acetate; Up-Regulation | 2006 |
Airway inflammation in asymptomatic children with episodic wheeze.
Topics: Asthma; Brefeldin A; Bronchi; Bronchoalveolar Lavage Fluid; CD3 Complex; CD4-Positive T-Lymphocytes; Cell Count; Child; Child, Preschool; Eosinophils; Female; HLA-DR Antigens; Humans; Immunoglobulin E; Inflammation; Interferon-gamma; Interleukin-2 Receptor alpha Subunit; Interleukins; Ionomycin; Lymphocytes; Male; Neutrophils; Respiratory Sounds; T-Lymphocyte Subsets; Tetradecanoylphorbol Acetate | 2006 |
Suppression by WIN55212-2, a cannabinoid receptor agonist, of inflammatory reactions in mouse ear: Interference with the actions of an endogenous ligand, 2-arachidonoylglycerol.
Topics: Administration, Cutaneous; Animals; Arachidonic Acids; Benzoxazines; Calcium; Cannabinoid Receptor Agonists; Cannabinoids; Cell Movement; Cyclohexanols; Dose-Response Relationship, Drug; Ear, External; Endocannabinoids; Glycerides; HL-60 Cells; Humans; Inflammation; Intracellular Fluid; Leukocytes; Ligands; Male; Mice; Mice, Inbred ICR; Morpholines; Naphthalenes; Peroxidase; Tetradecanoylphorbol Acetate | 2006 |
In vivo efficacy study of the anti-inflammatory properties of Surolan.
Topics: Analysis of Variance; Animals; Anti-Inflammatory Agents; Disease Models, Animal; Ear; Female; Inflammation; Mice; Mice, Inbred Strains; Otitis Externa; Prednisolone; Random Allocation; Tetradecanoylphorbol Acetate; Treatment Outcome | 2006 |
Z39Ig is expressed on macrophages and may mediate inflammatory reactions in arthritis and atherosclerosis.
Topics: Antibodies, Monoclonal; Antigen-Antibody Reactions; Arthritis; Atherosclerosis; Cell Line; Humans; Immunohistochemistry; Inflammation; Interleukin-8; Macrophages; Matrix Metalloproteinase 9; NF-kappa B; Receptors, Complement; Tetradecanoylphorbol Acetate | 2006 |
Down syndrome candidate region 1 increases the stability of the IkappaBalpha protein: implications for its anti-inflammatory effects.
Topics: Anti-Inflammatory Agents; Cell Line, Tumor; Cyclooxygenase 2; DNA-Binding Proteins; Down Syndrome; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; I-kappa B Proteins; Inflammation; Intracellular Signaling Peptides and Proteins; Kinetics; Muscle Proteins; NF-KappaB Inhibitor alpha; Tetradecanoylphorbol Acetate; Time Factors; Transcriptional Activation; Transfection | 2006 |
Neutrophil activator of matrix metalloproteinase-2 (NAM).
Topics: Adult; Amides; Calcimycin; Cathepsin G; Cathepsins; Cells, Cultured; Culture Media, Conditioned; Endothelium, Vascular; Enzyme Activation; Enzyme Precursors; Humans; Inflammation; Ionomycin; Matrix Metalloproteinase 14; Matrix Metalloproteinase 2; Neoplasm Invasiveness; Neoplasm Metastasis; Neutrophils; Oligopeptides; Pancreatic Elastase; Phenylalanine; Protease Inhibitors; Proteins; RNA, Messenger; Serine Endopeptidases; Substrate Specificity; Tetradecanoylphorbol Acetate; Thiophenes; Tissue Inhibitor of Metalloproteinase-2; Umbilical Veins | 2006 |
Kit is essential for PMA-inflammation-induced mast-cell accumulation in the skin.
Topics: Animals; Cell Count; Immunity; Inflammation; Lymphocytes; Mast Cells; Mice; Mice, Inbred Strains; Proto-Oncogene Proteins c-kit; Signal Transduction; Skin; Tetradecanoylphorbol Acetate | 2007 |
CD40 ligand mediates inflammation independently of CD40 by interaction with Mac-1.
Topics: Animals; Aorta, Thoracic; Aortic Diseases; Atherosclerosis; CD40 Ligand; Chemotaxis, Leukocyte; CHO Cells; Cholesterol, Dietary; Cricetinae; Cricetulus; Crosses, Genetic; Diet, Atherogenic; Foam Cells; Genetic Predisposition to Disease; Humans; Inflammation; Lipids; Macrophage-1 Antigen; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Biological; Monocytes; Peritonitis; Peroxidase; Receptors, LDL; Rheology; Tetradecanoylphorbol Acetate | 2007 |
Involvement of mast cells in the regulation of matrix metalloproteinase-9 and tissue inhibitor of metalloproteases-1 in 12-O-tetradecanoylphorbolacetate-induced inflammation in mice.
Topics: Animals; Blotting, Western; Cell Degranulation; Ear, External; Inflammation; Mast Cells; Matrix Metalloproteinase 9; Mice; Tetradecanoylphorbol Acetate; Tissue Inhibitor of Metalloproteinase-1 | 2007 |
Influence of the fungal NF-kappaB inhibitor panepoxydone on inflammatory gene expression in MonoMac6 cells.
Topics: Apoptosis; Autoimmune Diseases; Blotting, Western; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Tumor; Cell Survival; Electrophoretic Mobility Shift Assay; Fluorescein-5-isothiocyanate; Gene Expression; Genes, Reporter; Humans; Inflammation; Lipopolysaccharides; NF-kappa B; Nitriles; Oligonucleotide Array Sequence Analysis; Propidium; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfones; Tetradecanoylphorbol Acetate | 2007 |
Dihydrolipoic acid inhibits skin tumor promotion through anti-inflammation and anti-oxidation.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Cyclooxygenase 2; Dinoprostone; Disease Models, Animal; Drug Interactions; Female; Inflammation; Lipopolysaccharides; Mice; Nitric Oxide Synthase Type II; Nitrites; Oxidation-Reduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Thioctic Acid | 2007 |
PMA activates Stat3 in the Jak/Stat pathway and induces SOCS5 in rat brain astrocytes.
Topics: Animals; Astrocytes; Brain; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; Inflammation; Interferon-gamma; Janus Kinases; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Phosphotyrosine; Protein Binding; Proto-Oncogene Proteins pp60(c-src); Rats; Rats, Sprague-Dawley; Response Elements; STAT3 Transcription Factor; Suppressor of Cytokine Signaling Proteins; Tetradecanoylphorbol Acetate | 2007 |
The atypical chemokine receptor D6 suppresses the development of chemically induced skin tumors.
Topics: Animals; Chemokine Receptor D6; Disease Susceptibility; Disease-Free Survival; Epithelial Cells; Female; Gene Expression Regulation, Neoplastic; Humans; Inflammation; Keratinocytes; Mice; Mice, Transgenic; Neoplasm Invasiveness; Papilloma; Receptors, CCR10; Receptors, Chemokine; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 2007 |
Potential role for epidermal Langerhans cells in nicotinic acid-induced vasodilatation in the mouse.
Topics: Animals; Epidermis; Hydrocortisone; Indomethacin; Inflammation; Langerhans Cells; Laser-Doppler Flowmetry; Male; Mice; Mice, Inbred C57BL; Niacin; Tetradecanoylphorbol Acetate; Vasodilator Agents | 2007 |
Effects of Prunella vulgaris on mast cell-mediated allergic reaction and inflammatory cytokine production.
Topics: Animals; Cytokines; Histamine; Hypersensitivity; Inflammation; Ionophores; Male; Mast Cells; Mice; Mice, Inbred ICR; NF-kappa B; Plant Extracts; Prunella; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2007 |
Effects of naturally occurring dihydroflavonols from Inula viscosa on inflammation and enzymes involved in the arachidonic acid metabolism.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Cell Survival; Dinoprostone; Edema; Female; Flavonols; Histamine Release; Humans; In Vitro Techniques; Inflammation; Inula; Leukocyte Elastase; Leukotriene B4; Mice; Neutrophils; Peroxidase; Phospholipases A; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate | 2007 |
Berberine suppresses inflammatory agents-induced interleukin-1beta and tumor necrosis factor-alpha productions via the inhibition of IkappaB degradation in human lung cells.
Topics: Alkaloids; Anti-Inflammatory Agents; Benzophenanthridines; Berberine; Cell Survival; Ceramides; Dose-Response Relationship, Drug; Epithelial Cells; Fibroblasts; Humans; Hydrogen Peroxide; I-kappa B Proteins; Inflammation; Interleukin-1beta; Isoquinolines; Lipopolysaccharides; Lung; NF-KappaB Inhibitor alpha; Okadaic Acid; Phosphorylation; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; U937 Cells | 2007 |
Not in the mind of neurasthenic lazybones but in the cell nucleus: patients with chronic fatigue syndrome have increased production of nuclear factor kappa beta.
Topics: Adult; Case-Control Studies; Cell Nucleus; Fatigue Syndrome, Chronic; Female; Humans; Inflammation; Lymphocytes; Male; Middle Aged; Neurasthenia; NF-kappa B; Oxidative Stress; Severity of Illness Index; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2007 |
Negative regulation of inducible nitric-oxide synthase expression mediated through transforming growth factor-beta-dependent modulation of transcription factor TCF11.
Topics: Animals; Carcinogens; Cells, Cultured; Dimerization; Disease Models, Animal; Endotoxemia; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Hepatocyte Nuclear Factor 1-beta; Humans; Inflammation; MafG Transcription Factor; Male; Mutation; Naphthalenes; Nitric Oxide Synthase Type II; Protein Kinase C; Rats; Rats, Sprague-Dawley; Repressor Proteins; Response Elements; RNA, Small Interfering; Signal Transduction; Smad6 Protein; Smad7 Protein; Staurosporine; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta1 | 2007 |
A catalytically independent physiological function for human acute phase protein group IIA phospholipase A2: cellular uptake facilitates cell debris removal.
Topics: Acute-Phase Proteins; Amino Acid Substitution; Anions; Arthritis, Rheumatoid; Cell Line; Cell Nucleus; Gene Expression Regulation, Enzymologic; Group II Phospholipases A2; Heparan Sulfate Proteoglycans; Humans; Hydrolysis; Inflammation; Mutation, Missense; Phospholipids; Pinocytosis; Protein Binding; Protein Transport; Synovial Fluid; Tetradecanoylphorbol Acetate; Transport Vesicles; Wounds and Injuries | 2008 |
Topical transduction of superoxide dismutase mediated by HIV-1 Tat protein transduction domain ameliorates 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced inflammation in mice.
Topics: Administration, Cutaneous; Animals; Anti-Inflammatory Agents; Cell Line; Cyclooxygenase 2; Cytokines; Dinoprostone; HIV-1; Humans; Inflammation; Male; Mice; Mice, Inbred ICR; Mitogen-Activated Protein Kinases; Nitric Oxide Synthase Type II; Protein Structure, Tertiary; Reactive Oxygen Species; Recombinant Fusion Proteins; Skin Diseases; Superoxide Dismutase; tat Gene Products, Human Immunodeficiency Virus; Tetradecanoylphorbol Acetate | 2008 |
Avarol inhibits TNF-alpha generation and NF-kappaB activation in human cells and in animal models.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Cell Line; Disease Models, Animal; Dose-Response Relationship, Drug; Epidermis; Female; Humans; Hyperplasia; Inflammation; Inflammation Mediators; Keratinocytes; Mice; Monocytes; NF-kappa B p50 Subunit; Peroxidase; Psoriasis; Sesquiterpenes; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2008 |
HIF-1alpha regulates epithelial inflammation by cell autonomous NFkappaB activation and paracrine stromal remodeling.
Topics: Active Transport, Cell Nucleus; Animals; Carcinogens; Cell Nucleus; Cytokines; Drug Hypersensitivity; Epithelium; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammation; Keratinocytes; Mice; Mice, Transgenic; Paracrine Communication; Phosphorylation; Signal Transduction; Stromal Cells; Tetradecanoylphorbol Acetate; Transcription Factor RelA; Transcription, Genetic; Up-Regulation | 2008 |
RAGE signaling sustains inflammation and promotes tumor development.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Gene Expression Regulation, Neoplastic; Inflammation; Macrophage Inflammatory Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptor for Advanced Glycation End Products; Receptors, Immunologic; S100 Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2008 |
The involvement of nitric oxide, nitric oxide synthase, neutrophil elastase, myeloperoxidase and proinflammatory cytokines in the acute lung injury caused by phorbol myristate acetate.
Topics: Animals; Cytokines; In Vitro Techniques; Inflammation; Leukocyte Elastase; Lung; Male; Neutrophil Activation; Nitric Oxide; Nitric Oxide Synthase Type II; Peroxidase; Rats; Rats, Sprague-Dawley; Respiratory Distress Syndrome; RNA, Messenger; Tetradecanoylphorbol Acetate | 2008 |
Kruppel-like factor 4 is essential for inflammatory monocyte differentiation in vivo.
Topics: Animals; Carcinogens; Cell Differentiation; Granulocytes; Hematopoietic Stem Cells; HL-60 Cells; Humans; Inflammation; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Monocytes; Myelopoiesis; Tetradecanoylphorbol Acetate | 2008 |
Inhibitory effects of falconensins on 12-O-tetradecanoylphorbol-13-acetate-induced inflammatory ear edema in mice.
Topics: Animals; Anti-Inflammatory Agents; Benzopyrans; Disease Models, Animal; Ear; Edema; Emericella; Female; Indomethacin; Inflammation; Mice; Mice, Inbred ICR; Pigments, Biological; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 2008 |
Inhibitory effect of the rhizomes of Alpinia officinarum on TPA-induced inflammation and tumor promotion in two-stage carcinogenesis in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alpinia; Animals; Anti-Inflammatory Agents; Anticarcinogenic Agents; Carcinogens; Diarylheptanoids; Female; Inflammation; Inhibitory Concentration 50; Mice; Mice, Inbred ICR; Neoplasms, Experimental; Plant Extracts; Rhizome; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2008 |
Anti-inflammatory effects of dimemorfan on inflammatory cells and LPS-induced endotoxin shock in mice.
Topics: Animals; Anti-Inflammatory Agents; Blotting, Western; Calcium; Cytokines; Fluorescent Antibody Technique; Humans; I-kappa B Proteins; Inflammation; Lipopolysaccharides; Macrophage-1 Antigen; Mice; Morphinans; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Nitric Oxide; Nitric Oxide Synthase Type II; Reactive Oxygen Species; Shock, Septic; Tetradecanoylphorbol Acetate; Transcription Factor RelA; Up-Regulation | 2008 |
Prostaglandin E-mediated mitogenic stimulation of mouse epidermis in vivo by divalent cation ionophore A 23187 and by tumor promoter 12-O-tetradecanoylphorbol-13-acetate.
Topics: Animals; Anti-Bacterial Agents; Calcimycin; Catecholamines; Cyclic AMP; Enzyme Induction; Epidermal Cells; Epidermis; Inflammation; Mast Cells; Mice; Mitosis; Phorbols; Prostaglandins E; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1981 |
Retinoid inhibition of superoxide anion radical production by human polymorphonuclear leukocytes stimulated with tumor promoters.
Topics: Alkaloids; Antipain; Cocarcinogenesis; Diterpenes; Humans; Indoles; Inflammation; Lyngbya Toxins; Neutrophils; Oxygen; Phorbol Esters; Phorbols; Superoxides; Terpenes; Tetradecanoylphorbol Acetate; Tretinoin; Vitamin A | 1980 |
The role of polymorphonuclear peroxidase-dependent oxidants in inflammation.
Topics: Animals; Arachidonic Acids; Cattle; Ethanol; Humans; Inflammation; Neutrophils; Peroxidase; Peroxidases; Phagocytosis; Prostaglandins; Sulfides; Tetradecanoylphorbol Acetate | 1980 |
Stimulated human phagocytes produce cytogenetic changes in cultured mammalian cells.
Topics: Animals; Cells, Cultured; Cricetinae; Cricetulus; Crossing Over, Genetic; Female; Humans; Inflammation; Neoplasms; Ovary; Oxygen; Phagocytes; Sister Chromatid Exchange; Superoxides; Tetradecanoylphorbol Acetate | 1983 |
Regulation of neutrophil inflammatory mediator release: chemotactic peptide activation of stimulus-dependent cytotoxicity.
Topics: Chemotactic Factors; Chromium Radioisotopes; Cytotoxicity, Immunologic; Granulomatous Disease, Chronic; Humans; Hydrogen Peroxide; Inflammation; Interleukin-8; Male; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Peroxidase; Tetradecanoylphorbol Acetate | 1983 |
The oxidative burst and related phenomena in mouse macrophages elicited by different sterile inflammatory stimuli.
Topics: Animals; Cytotoxicity, Immunologic; Female; Guinea Pigs; Hydrogen Peroxide; Inflammation; Iodine Radioisotopes; Lectins; Macrophage Activation; Macrophages; Mice; Mice, Inbred BALB C; Oxygen; Superoxides; Tetradecanoylphorbol Acetate; Wheat Germ Agglutinins; Zymosan | 1983 |
Proteases and oxidants in experimental pulmonary inflammatory injury.
Topics: Animals; Catalase; Disease Models, Animal; Glucose; Glucose Oxidase; Glutathione; Hydrogen Peroxide; Inflammation; Lung; Lung Injury; Neutrophils; Oligopeptides; Oxidation-Reduction; Peptide Hydrolases; Rabbits; Tetradecanoylphorbol Acetate | 1984 |
Cyclooxygenase inhibition during phorbol-induced granulocyte stimulation in awake sheep.
Topics: Animals; Consciousness; Cyclooxygenase Inhibitors; Granulocytes; Hypertension, Pulmonary; Hypoxia; Inflammation; Lung Diseases; Lymph; Meclofenamic Acid; Phorbols; Sheep; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1984 |
Stimulation of ornithine decarboxylase activity and DNA synthesis by phorbol esters or bile acids in rat colon.
Topics: Animals; Bile Acids and Salts; Colon; Deoxycholic Acid; DNA; Enzyme Activation; Epithelium; Inflammation; Intestinal Mucosa; Male; Ornithine Decarboxylase; Phorbol Esters; Phorbols; Rats; Rats, Inbred Strains; Rectum; Stimulation, Chemical; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1984 |
Different biological targets for resiniferatoxin and phorbol 12-myristate 13-acetate.
Topics: Animals; Biological Transport; Cells, Cultured; Chick Embryo; Deoxyglucose; Diterpenes; Dose-Response Relationship, Drug; Fibronectins; Inflammation; Mice; Phorbols; Plasminogen Activators; Tetradecanoylphorbol Acetate | 1980 |
Hypotheses on the molecular mechanism of action of tumor promoters.
Topics: Animals; Carcinogens; Humans; Inflammation; Models, Biological; Molecular Conformation; Phospholipases A; Phospholipases A2; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1981 |
Structure-activity relationships in chick embryo fibroblasts for phorbol-related diterpene esters showing anomalous activities in vivo.
Topics: Animals; Cells, Cultured; Chick Embryo; Deoxy Sugars; Deoxyglucose; Fibroblasts; Fibronectins; Inflammation; Mice; Neoplasms, Experimental; Phorbol Esters; Phorbols; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1980 |
Flow cytofluorometric detection of inflammatory processes by measuring respiratory burst reaction of peripheral blood neutrophils.
Topics: Flow Cytometry; Humans; Inflammation; Neutrophils; Respiratory Burst; Tetradecanoylphorbol Acetate | 1995 |
The antiinflammatory activity of topically applied novel calcium-channel antagonists.
Topics: Administration, Cutaneous; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Calcium; Calcium Channel Blockers; Chemotaxis, Leukocyte; Clobetasol; Ear, External; Epidermis; Female; Humans; Hyperplasia; Inflammation; Mice; Neutrophils; Nifedipine; Peroxidase; Phosphatidylinositol Diacylglycerol-Lyase; Phosphodiesterase Inhibitors; Phospholipases A; Phosphoric Diester Hydrolases; Pituitary Neoplasms; Potassium Chloride; Pyrazoles; Terpenes; Tetradecanoylphorbol Acetate; Thyrotropin-Releasing Hormone; Tumor Cells, Cultured | 1995 |
Inhibition of inflammatory responses by epitaondiol and other marine natural products.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Blood Platelets; Calcimycin; Cytochrome c Group; Ear, External; Edema; Humans; Inflammation; Leukotriene B4; Mice; Neutrophils; Oxidation-Reduction; Phospholipases A; Phospholipases A2; Sesquiterpenes; Steroids; Stimulation, Chemical; Superoxides; Terpenes; Tetradecanoylphorbol Acetate; Thromboxane B2 | 1995 |
Identification and characterization of rhesus macaque interleukin-8.
Topics: Amino Acid Sequence; Animals; Antibodies, Monoclonal; Base Sequence; Chemotaxis, Leukocyte; Chromatography, Ion Exchange; Cloning, Molecular; Edema; Female; Genes; Humans; Inflammation; Interleukin-8; Macaca mulatta; Mammals; Molecular Sequence Data; Neutrophils; Open Reading Frames; Sequence Homology, Amino Acid; Species Specificity; Tetradecanoylphorbol Acetate | 1995 |
Leukotriene-deficient mice generated by targeted disruption of the 5-lipoxygenase gene.
Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Bone Marrow Cells; Carrageenan; Dinoprostone; Female; Inflammation; Leukotriene C4; Leukotrienes; Macrophages; Male; Mast Cells; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Mutant Strains; Phagocytosis; Phenotype; Platelet Activating Factor; Spleen; Tetradecanoylphorbol Acetate | 1995 |
Arachidonic acid liberation from rat tracheal epithelial cells by alveolar macrophages.
Topics: Animals; Animals, Newborn; Arachidonic Acid; Bronchoalveolar Lavage Fluid; Calcimycin; Cells, Cultured; Culture Media, Conditioned; Epithelium; Inflammation; Macrophages, Alveolar; Rats; Tetradecanoylphorbol Acetate; Trachea | 1995 |
In vitro glycolysis of whole blood can detect primed neutrophils in septic ICU patients.
Topics: Adult; Aged; Critical Care; Erythrocyte Count; Female; Glycolysis; Humans; In Vitro Techniques; Inflammation; Leukocyte Count; Male; Middle Aged; Models, Statistical; Neutrophils; Probability; Reference Values; Sepsis; Shock, Septic; Tetradecanoylphorbol Acetate | 1995 |
Radicicol, a protein tyrosine kinase inhibitor, suppresses the expression of mitogen-inducible cyclooxygenase in macrophages stimulated with lipopolysaccharide and in experimental glomerulonephritis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibodies; Antifungal Agents; Basement Membrane; Blotting, Western; Gene Expression; Glomerulonephritis; Glyceraldehyde-3-Phosphate Dehydrogenases; Inflammation; Isoenzymes; Kidney Glomerulus; Kinetics; Lactones; Lipopolysaccharides; Macrolides; Macrophages, Alveolar; Mitogens; Molecular Structure; Prostaglandin-Endoperoxide Synthases; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors | 1995 |
Effects of ZCR-2060 on allergic airway inflammation and cell activation in guinea-pigs.
Topics: Animals; Benzoates; Bronchoalveolar Lavage Fluid; Chemotaxis, Leukocyte; Eosinophils; Guinea Pigs; Inflammation; Leukotriene B4; Macrophages, Alveolar; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Piperidines; Platelet Activating Factor; Respiratory Hypersensitivity; Superoxides; Tetradecanoylphorbol Acetate | 1994 |
Response of fibroblast cultures from ataxia-telangiectasia patients to reactive oxygen species generated during inflammatory reactions.
Topics: Ataxia Telangiectasia; Cell Line; Cells, Cultured; DNA Damage; DNA Repair; DNA, Single-Stranded; Fibroblasts; Humans; Inflammation; Micronucleus Tests; Oxidative Stress; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; X-Rays; Xanthine; Xanthine Oxidase; Xanthines | 1994 |
Interleukin-1 alpha mediates phorbol ester-induced inflammation and epidermal hyperplasia.
Topics: Analysis of Variance; Animals; Capillary Permeability; Cell Movement; Epidermis; Female; Hyperplasia; Immunohistochemistry; Inflammation; Interleukin-1; Mice; Mice, Inbred SENCAR; Recombinant Proteins; Tetradecanoylphorbol Acetate | 1994 |
Whole blood chemiluminescence as a systemic inflammatory parameter in asthma.
Topics: Adult; Aged; Aged, 80 and over; Airway Obstruction; Asthma; Blood Cell Count; Bronchodilator Agents; Humans; Inflammation; Luminescent Measurements; Middle Aged; Reference Values; Spirometry; Tetradecanoylphorbol Acetate | 1994 |
Phorbol ester-induced leukotriene biosynthesis and tumor promotion in mouse epidermis.
Topics: Animals; Ear, External; Edema; Epidermis; Female; Hyperplasia; Indoles; Inflammation; Leukotriene B4; Mice; Skin Neoplasms; SRS-A; Tetradecanoylphorbol Acetate | 1994 |
Effect of lysophosphatidic acid on motility, polarisation and metabolic burst of human neutrophils.
Topics: Cell Movement; Cell Polarity; Cell Size; Dose-Response Relationship, Drug; Drug Interactions; GTP-Binding Proteins; Humans; Inflammation; Lysophospholipids; Neutrophils; Pertussis Toxin; Respiratory Burst; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1994 |
Avarol and avarone, two new anti-inflammatory agents of marine origin.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Carrageenan; Cyclohexenes; Edema; Indomethacin; Inflammation; Leukocytes; Male; Mice; Peritoneum; Phospholipases A; Phospholipases A2; Rats; Sesquiterpenes; Superoxides; Tetradecanoylphorbol Acetate | 1994 |
Inhibitory effect of karounidiol on 12-O-tetradecanoylphorbol-13-acetate-induced tumor promotion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Cocarcinogenesis; Female; Inflammation; Mice; Mice, Inbred ICR; Oleanolic Acid; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Triterpenes | 1994 |
Priming effect of hydroxyapatite on the chemiluminescence response in human polymorphonuclear leukocytes.
Topics: Calcimycin; Dose-Response Relationship, Drug; Durapatite; Humans; Inflammation; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Sodium Fluoride; Tetradecanoylphorbol Acetate; Time Factors; Zymosan | 1994 |
Effects of (D-Ala2)methionine enkephalinamide in PMA-induced mouse ear edema.
Topics: Animals; Dose-Response Relationship, Drug; Ear; Edema; Enkephalin, Methionine; Female; Inflammation; Mice; Reactive Oxygen Species; Respiratory Burst; Tetradecanoylphorbol Acetate | 1994 |
Activated T-cell adhesion to thrombospondin is mediated by the alpha 4 beta 1 (VLA-4) and alpha 5 beta 1 (VLA-5) integrins.
Topics: CD4-Positive T-Lymphocytes; Cell Adhesion; Chromatography, Affinity; Humans; Immunologic Memory; In Vitro Techniques; Inflammation; Leukocyte Common Antigens; Lymphocyte Activation; Platelet Membrane Glycoproteins; Receptors, Fibronectin; Receptors, Leukocyte-Adhesion; Receptors, Very Late Antigen; Tetradecanoylphorbol Acetate; Thrombospondins | 1993 |
Effects of CGRP in different models of mouse ear inflammation.
Topics: Analysis of Variance; Animals; Arachidonic Acid; Calcitonin Gene-Related Peptide; Cantharidin; Capsaicin; Croton Oil; Disease Models, Animal; Dose-Response Relationship, Drug; Ear; Inflammation; Male; Mice; Tetradecanoylphorbol Acetate | 1994 |
Effects of flavonoids on Naja naja and human recombinant synovial phospholipases A2 and inflammatory responses in mice.
Topics: Animals; Chromones; Edema; Flavanones; Flavones; Flavonoids; Galactosides; Humans; Inflammation; Kaempferols; Male; Mice; Phospholipases A; Phospholipases A2; Quercetin; Recombinant Proteins; Snakes; Tetradecanoylphorbol Acetate | 1994 |
Suppression of inflammatory responses to 12-O-tetradecanoyl-phorbol-13-acetate and carrageenin by YM-26734, a selective inhibitor of extracellular group II phospholipase A2.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Carrageenan; Chromans; Cyclooxygenase Inhibitors; Ear, External; Edema; Extracellular Space; Female; In Vitro Techniques; Inflammation; Lipoxygenase Inhibitors; Male; Mice; Mice, Inbred ICR; Phenols; Phospholipases A; Phospholipases A2; Pleurisy; Rabbits; Rats; Rats, Wistar; Sheep; Tetradecanoylphorbol Acetate | 1993 |
Anti-inflammatory properties of the protein kinase C inhibitor, 3-[1-[3-(dimethylamino)propyl]-1H-indol-3-yl]-4-(1H-indol-3-yl)-1H- pyrrole-2,5-dione monohydrochloride (GF109203X) in the PMA-mouse ear edema model.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Ear; Edema; Eicosanoids; Female; Indoles; Inflammation; Maleimides; Mice; Neutrophils; Peroxidase; Protein Kinase C; Radioimmunoassay; Tetradecanoylphorbol Acetate | 1993 |
Topical tretinoin prevents corticosteroid-induced atrophy without lessening the anti-inflammatory effect.
Topics: Administration, Cutaneous; Animals; Atrophy; Croton Oil; Drug Eruptions; Ear, External; Edema; Female; Fibronectins; Glucocorticoids; Glycosaminoglycans; Inflammation; Mice; Mice, Hairless; Skin; Tetradecanoylphorbol Acetate; Tretinoin | 1993 |
Cell type specific expression of members of the IL-8/NAP-1 gene family.
Topics: Cell Differentiation; Chemokine CXCL10; Chemokines, CXC; Cytokines; Fibroblasts; Gene Expression Regulation; Humans; Inflammation; Interleukin-8; Monocytes; Phytohemagglutinins; Platelet Factor 4; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1993 |
Interleukin-1 alpha gene expression and localization of interleukin-1 alpha protein during tumor promotion.
Topics: Acetone; Animals; Antibodies; Autoradiography; Blotting, Northern; Cell Division; Gene Expression; Immunohistochemistry; Inflammation; Interleukin-1; Keratinocytes; Mice; Mice, Inbred Strains; Polymerase Chain Reaction; Recombinant Proteins; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Thymidine; Tritium | 1993 |
Enhancement of wound healing by the alkaloid taspine defining mechanism of action.
Topics: Alkaloids; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Division; Cell Line; Chemotaxis; Chemotaxis, Leukocyte; DNA Replication; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Inflammation; Lung; Macrophages; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phagocytosis; Rats; Rats, Sprague-Dawley; Superoxides; Tetradecanoylphorbol Acetate; Thymidine; Wound Healing; Wounds and Injuries | 1993 |
Human neutrophil adhesion to bovine aortic endothelium. Evidence for endothelial lipoxygenase activity.
Topics: Animals; Arachidonic Acid; Cattle; Cell Adhesion; Cells, Cultured; Endothelium, Vascular; Humans; Inflammation; Leukotriene B4; Lipoxygenase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Tetradecanoylphorbol Acetate; Thrombin | 1993 |
Effects of human neutrophil elastase (HNE) on neutrophil function in vitro and in inflamed microvessels.
Topics: Animals; Cell Adhesion; Cephalosporins; Chemotaxis, Leukocyte; Endothelium, Vascular; Humans; Inflammation; Leukocyte Elastase; Male; Microcirculation; Neutrophils; Pancreatic Elastase; Platelet Activating Factor; Pyrrolidines; Rats; Rats, Wistar; Splanchnic Circulation; Superoxides; Tetradecanoylphorbol Acetate; Umbilical Veins; Venules | 1993 |
Relationship of oxidative events and DNA oxidation in SENCAR mice to in vivo promoting activity of phorbol ester-type tumor promoters.
Topics: Animals; Carcinogens; Catechin; Diterpenes; DNA; DNA Damage; Female; Hydrogen Peroxide; Inflammation; Mice; Mice, Inbred Strains; Neutrophils; Oxidation-Reduction; Phorbol Esters; Skin; Tamoxifen; Terpenes; Tetradecanoylphorbol Acetate | 1993 |
Fucoidin, a potent inhibitor of leukocyte rolling, prevents neutrophil influx into phorbol-ester-induced inflammatory sites in rabbit lungs.
Topics: Animals; In Vitro Techniques; Inflammation; Leukocytes; Lung; Male; Neutrophils; Peritoneum; Peritonitis; Polysaccharides; Rabbits; Sulfuric Acid Esters; Tetradecanoylphorbol Acetate; Thioglycolates | 1996 |
Inhibitory effect of some oxygenated stigmastane-type sterols on 12-O-tetradecanoylphorbol-13-acetate-induced inflammation in mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Ear, External; Edema; Female; Inflammation; Mice; Mice, Inbred ICR; Phytosterols; Tetradecanoylphorbol Acetate | 1995 |
4-Alkoxybenzamidines as new potent phospholipase A2 inhibitors.
Topics: Acute Disease; Animals; Benzamidines; Carrageenan; Cattle; Chronic Disease; Disease Models, Animal; Edema; Enzyme Inhibitors; Inflammation; Kinetics; Male; Mice; Phospholipases A; Phospholipases A2; Rabbits; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1996 |
Cloning of human Bcl-2 homologue: inflammatory cytokines induce human A1 in cultured endothelial cells.
Topics: Amino Acid Sequence; Apoptosis; Base Sequence; Cloning, Molecular; Cytokines; DNA-Binding Proteins; DNA, Complementary; Endothelial Growth Factors; Endothelium, Vascular; Fibroblast Growth Factor 2; Gene Expression Regulation; Genes; Homeodomain Proteins; Humans; Inflammation; Lymphokines; Minor Histocompatibility Antigens; Molecular Sequence Data; Multigene Family; Polymerase Chain Reaction; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Replication Protein C; Repressor Proteins; Saccharomyces cerevisiae Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Species Specificity; Tetradecanoylphorbol Acetate; Umbilical Veins; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1996 |
Conditions to study nitric oxide generation by polymorphonuclear cells from an inflammatory exudate in rats.
Topics: Animals; Arginine; Carrageenan; Enzyme Inhibitors; Exudates and Transudates; Inflammation; Kinetics; Neutrophils; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Ornithine; Rats; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1996 |
Infusion of ovine C5a into sheep mimics the inflammatory response of hemodialysis.
Topics: Amino Acid Sequence; Animals; Blood Pressure; Complement C5a; Disease Models, Animal; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Humans; Inflammation; Kinetics; Leukocyte Count; Molecular Sequence Data; Neutropenia; Neutrophils; Renal Dialysis; Respiratory Burst; Sequence Homology; Sheep; Tetradecanoylphorbol Acetate | 1996 |
Identification and characterization of a high-affinity leukotriene B4 receptor on guinea pig T lymphocytes and its regulation by lipoxin A4.
Topics: Animals; Carbazoles; Female; Guinea Pigs; Hydroxyeicosatetraenoic Acids; Indole Alkaloids; Inflammation; Leukotriene B4; Lipoxins; Protein Kinase C; Receptors, Leukotriene B4; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1996 |
The proteinase-activated receptor 2 is induced by inflammatory mediators in human endothelial cells. Comparison with the thrombin receptor.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Blotting, Northern; Cell Adhesion Molecules; Cell Line; Cells, Cultured; Chlorocebus aethiops; Colforsin; DNA Probes; Down-Regulation; Endothelium, Vascular; Humans; Inflammation; Interleukin-1; Kinetics; Lipopolysaccharides; Receptor, PAR-2; Receptors, Cell Surface; Receptors, Thrombin; Recombinant Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Tumor Necrosis Factor-alpha; Umbilical Veins | 1996 |
Changes of fatty acid composition and oxidative metabolism of human neutrophils migrating into an inflammatory exudate.
Topics: Chemotaxis, Leukocyte; Exudates and Transudates; Fatty Acids; Humans; Inflammation; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidation-Reduction; Respiratory Burst; Skin Window Technique; Tetradecanoylphorbol Acetate | 1996 |
Inflammatory and hyperproliferative skin disease in mice that express elevated levels of the IL-1 receptor (type I) on epidermal keratinocytes. Evidence that IL-1-inducible secondary cytokines produced by keratinocytes in vivo can cause skin disease.
Topics: Animals; Cells, Cultured; Chemokine CXCL1; Chemokines, CXC; Chemotactic Factors; Crosses, Genetic; Cytokines; Ear; Flow Cytometry; Gene Expression; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Substances; Inflammation; Intercellular Signaling Peptides and Proteins; Interleukin-1; Keratinocytes; Mice; Mice, Transgenic; Organ Specificity; Receptors, Interleukin-1; Reference Values; Skin; Skin Diseases; Tetradecanoylphorbol Acetate | 1996 |
Inhibition of phagocyte-endothelium interactions by oxidized fatty acids: a natural anti-inflammatory mechanism?
Topics: Animals; Base Sequence; Cell Adhesion; Cell Adhesion Molecules; Cell Survival; Eicosapentaenoic Acid; Endothelium, Vascular; Fatty Acids; Fatty Acids, Omega-3; Humans; Inflammation; Lipopolysaccharides; Molecular Probes; Molecular Sequence Data; NF-kappa B; Oxidation-Reduction; Phagocytes; Swine; Tetradecanoylphorbol Acetate | 1996 |
Inhibitory effects of sterols isolated from Chlorella vulgaris on 12-0-tetradecanoylphorbol-13-acetate-induced inflammation and tumor promotion in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogens; Cell Extracts; Chlorella; Chromatography; Ergosterol; Female; Inflammation; Mice; Mice, Inbred Strains; Molecular Structure; Skin; Skin Diseases; Sterols; Tetradecanoylphorbol Acetate | 1996 |
Leukocyte hydrogen peroxide production in a surgical wound in mice. The effects of an amide local anaesthetic.
Topics: Anesthetics, Local; Animals; Diffusion Chambers, Culture; Hydrogen Peroxide; Inflammation; Leukocytes; Lidocaine; Male; Mice; Tetradecanoylphorbol Acetate; Wound Healing; Wounds and Injuries | 1996 |
Suppression of inflammatory arthritis by simultaneous inhibition of nitric oxide synthase and NADPH oxidase.
Topics: Animals; Anti-Inflammatory Agents; Arthritis; Chromates; Enzyme Inhibitors; Glutathione Reductase; Inflammation; Luminescent Measurements; Male; Mice; Mice, Inbred Strains; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Onium Compounds; Peroxides; Reactive Oxygen Species; Superoxides; Tetradecanoylphorbol Acetate | 1996 |
Inhibitory effect of Di- and trihydroxy triterpenes from the flowers of compositae on 12-O-tetradecanoylphorbol-13-acetate-induced inflammation in mice.
Topics: Animals; Inflammation; Mice; Plants; Tetradecanoylphorbol Acetate; Triterpenes | 1996 |
An IkappaB homolog encoded by African swine fever virus provides a novel mechanism for downregulation of proinflammatory cytokine responses in host macrophages.
Topics: African Swine Fever Virus; Amino Acid Sequence; Animals; Cells, Cultured; DNA; DNA-Binding Proteins; Down-Regulation; Humans; I-kappa B Proteins; Inflammation; Interferon-alpha; Interleukin-8; Macrophages; Molecular Sequence Data; NF-kappa B; NF-KappaB Inhibitor alpha; Signal Transduction; Swine; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha; Viral Proteins | 1996 |
Triterpene alcohols from the flowers of compositae and their anti-inflammatory effects.
Topics: Alcohols; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Female; Inflammation; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred ICR; Plants; Tetradecanoylphorbol Acetate | 1996 |
Induction of prostaglandin H synthase-2 and tumor necrosis factor-alpha in human amnionic WISH cells by various stimuli occurs through distinct intracellular mechanisms.
Topics: Amnion; Base Sequence; Blotting, Northern; Cell Line; Cyclooxygenase 2; Dinoprostone; DNA Primers; Enzyme Induction; Female; Humans; Inflammation; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Isoenzymes; Kinetics; Membrane Proteins; Models, Biological; Molecular Sequence Data; Okadaic Acid; Polymerase Chain Reaction; Pregnancy; Prostaglandin-Endoperoxide Synthases; Recombinant Proteins; RNA, Messenger; Sialoglycoproteins; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Necrosis Factor-alpha | 1997 |
Effect of the basidiomycete Poria cocos on experimental dermatitis and other inflammatory conditions.
Topics: Administration, Oral; Administration, Topical; Animals; Anti-Inflammatory Agents; Arachidonic Acid; Basidiomycota; Carrageenan; Dermatitis; Female; Inflammation; Mice; Plant Extracts; Tetradecanoylphorbol Acetate; Triterpenes | 1997 |
Resting and stimulated human polymorphonuclear leucocytes from type-2 diabetic patients: change in purine nucleotide pattern.
Topics: Adenine Nucleotides; Adult; Case-Control Studies; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Guanine Nucleotides; Humans; In Vitro Techniques; Inflammation; Male; Middle Aged; Neutrophils; Purine Nucleotides; Respiratory Burst; Tetradecanoylphorbol Acetate | 1997 |
Activation of the NF-kappaB pathway by inflammatory stimuli in human neutrophils.
Topics: Base Sequence; Binding Sites; Cell Nucleus; Cells, Cultured; Cytokines; Dimerization; DNA-Binding Proteins; HIV; Humans; I-kappa B Proteins; Inflammation; Interferons; Interleukins; Leukotriene B4; Lipopolysaccharides; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; NF-kappa B; NF-KappaB Inhibitor alpha; Promoter Regions, Genetic; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-rel; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription Factor RelA; Transcription, Genetic; Tumor Necrosis Factor-alpha | 1997 |
Keratinocyte expression of the type 2 interleukin 1 receptor mediates local and specific inhibition of interleukin 1-mediated inflammation.
Topics: Animals; Animals, Genetically Modified; Cell Adhesion; Cells, Cultured; Dermatitis, Contact; Epidermal Cells; Epidermis; Granulocyte-Macrophage Colony-Stimulating Factor; Immunohistochemistry; Inflammation; Interleukin-1; Keratinocytes; Mice; Receptors, Interleukin-1; Receptors, Interleukin-1 Type II; Recombinant Proteins; Tetradecanoylphorbol Acetate | 1997 |
Cyclosporin A-sensitive calcium signaling represses NFkappaB activation in human bronchial epithelial cells and enhances NFkappaB activation in Jurkat T-cells.
Topics: Base Sequence; Bronchi; Calcium; Cell Line, Transformed; Cyclosporine; Epithelium; Genes, Reporter; Humans; Inflammation; Ionomycin; Jurkat Cells; Luciferases; NF-kappa B; Oligonucleotide Probes; Signal Transduction; Tacrolimus; Tetradecanoylphorbol Acetate; Transcriptional Activation; Transfection | 1997 |
Induction of the adhesion molecule CD44 by the pro-inflammatory cytokine interleukin-1 in endothelial cells.
Topics: Antigens, CD; Cell Line, Transformed; Cell Membrane; Endothelium, Vascular; Humans; Hyaluronan Receptors; Inflammation; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Kinetics; Sialoglycoproteins; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1997 |
Expression of TNF-alpha by human plasma cells in chronic inflammation.
Topics: Animals; Blotting, Western; Cells, Cultured; Chronic Disease; Culture Media, Conditioned; Enzyme-Linked Immunosorbent Assay; Humans; Inflammation; L Cells; Lymph Nodes; Lymphocyte Activation; Mice; Plasma Cells; Solubility; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1997 |
Expression of ST2, an interleukin-1 receptor homologue, is induced by proinflammatory stimuli.
Topics: 3T3 Cells; Animals; Base Sequence; Cell Division; Cell Line; Cells, Cultured; Cycloheximide; Cytokines; DNA Primers; Ear; Endothelium, Vascular; Fibroblasts; HL-60 Cells; Humans; Inflammation; Interleukin-1; Interleukin-1 Receptor-Like 1 Protein; Jurkat Cells; Membrane Proteins; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Organ Specificity; Polymerase Chain Reaction; Protein Biosynthesis; Receptors, Cell Surface; Receptors, Interleukin; Receptors, Interleukin-1; RNA, Messenger; Skin; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Ultraviolet Rays; Umbilical Veins | 1997 |
Inflammatory potency of activin A. Effect on prostanoid and nitric oxide formation.
Topics: Activins; Animals; Bone Marrow Cells; Cell Differentiation; Cinnamates; Cyclooxygenase 2; Dexamethasone; Enzyme Induction; Enzyme Inhibitors; Genistein; Inflammation; Inhibins; Interleukin-2; Isoenzymes; Lipopolysaccharides; Macrophages; Nitric Oxide; Nitric Oxide Synthase; Polymerase Chain Reaction; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Staurosporine; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Necrosis Factor-alpha; Tyrphostins | 1997 |
Induction and expression of human cartilage glycoprotein 39 in rheumatoid inflammatory and peripheral blood monocyte-derived macrophages.
Topics: Adipokines; Arthritis, Rheumatoid; Cartilage, Articular; Cell Differentiation; Cell Line; Cells, Cultured; Chitinase-3-Like Protein 1; Cholecalciferol; Cycloheximide; Glycoproteins; HL-60 Cells; Humans; Inflammation; Jurkat Cells; Kinetics; Lectins; Macrophages; Monocytes; Polymerase Chain Reaction; Recombinant Proteins; Reference Values; RNA, Messenger; Synovial Membrane; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1997 |
2-Chloro-4-(trifluoromethyl)pyrimidine-5-N-(3',5'- bis(trifluoromethyl)phenyl)-carboxamide: a potent inhibitor of NF-kappa B- and AP-1-mediated gene expression identified using solution-phase combinatorial chemistry.
Topics: Actins; Animals; Cytokines; Gene Expression Regulation; Humans; Immunosuppression Therapy; Inflammation; Interleukin-2; Interleukin-8; Jurkat Cells; Luciferases; Molecular Structure; NF-kappa B; Pyrimidines; Recombinant Fusion Proteins; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transfection | 1998 |
Nitric oxide inhibits superoxide production by inflammatory polymorphonuclear leukocytes.
Topics: Animals; Exudates and Transudates; Free Radicals; Inflammation; Male; Neutrophils; Nitric Oxide; Ornithine; Rats; Rats, Sprague-Dawley; Superoxides; Tetradecanoylphorbol Acetate | 1998 |
Degradation of glycosaminoglycans by reactive oxygen species derived from stimulated polymorphonuclear leukocytes.
Topics: Glycosaminoglycans; Humans; Hydroxides; Inflammation; Neutrophil Activation; Neutrophils; Reactive Oxygen Species; Superoxides; Tetradecanoylphorbol Acetate | 1997 |
Regulation of arachidonic acid release and metabolism by tumor promoters.
Topics: Animals; Animals, Newborn; Arachidonic Acid; Bradykinin; Calcimycin; Carcinogens; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Inflammation; Isoenzymes; Kinetics; Membrane Proteins; Mice; Mice, Inbred Strains; Phospholipases A; Prostaglandin-Endoperoxide Synthases; Protein Biosynthesis; Proteins; Skin; Tetradecanoylphorbol Acetate | 1997 |
Neutrophil behavior following exposure to in vivo or in vitro zinc in normal and acutely-inflamed rats: studies on lysozyme secretion, superoxide anion release and platelet adhesion.
Topics: Animals; Anti-Inflammatory Agents; Copper; Female; In Vitro Techniques; Inflammation; Liver; Muramidase; Neutrophils; Platelet Adhesiveness; Rats; Rats, Sprague-Dawley; Superoxides; Tetradecanoylphorbol Acetate; Zinc | 1998 |
Myoblasts produce IL-6 in response to inflammatory stimuli.
Topics: Adenylyl Cyclases; Calcimycin; Cells, Cultured; Humans; Inflammation; Interleukin-1; Interleukin-6; Muscles; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1998 |
Effect of dexamethasone on interleukin-1beta-(IL-1beta)-induced nuclear factor-kappaB (NF-kappaB) and kappaB-dependent transcription in epithelial cells.
Topics: Cell Line; Cyclooxygenase 2; Dexamethasone; DNA-Binding Proteins; Gene Expression Regulation; Glucocorticoids; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Inflammation; Interleukin-1; Isoenzymes; Lung; Membrane Proteins; NF-kappa B; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nuclear Proteins; Prostaglandin-Endoperoxide Synthases; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection | 1998 |
Distinct inflammatory responses of adherent vascular lung neutrophils to pulmonary irritants.
Topics: Animals; Anions; Cell Adhesion; Endotoxins; Female; Inflammation; Irritants; Leukocyte Count; Lung; Macrophages; Neutrophils; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Ozone; Rats; Rats, Sprague-Dawley; Superoxides; Tetradecanoylphorbol Acetate | 1998 |
Transforming growth factor-beta2 regulates C3 secretion in monocytes through a protein kinase C-dependent pathway.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Complement C3; Drug Interactions; Humans; Inflammation; Isoenzymes; Isoquinolines; Monocytes; Naphthalenes; Protein Kinase C; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta | 1998 |
Participation of peripheral polymorphonuclear leukocytes in the oxidative stress and inflammation in patients with essential hypertension.
Topics: Adult; Aged; Arteriosclerosis; Blood Pressure; Female; Glutathione; Humans; Hypertension; Inflammation; Male; Middle Aged; Neutrophils; Oxidative Stress; Superoxide Dismutase; Superoxides; Tetradecanoylphorbol Acetate | 1998 |
Inhibitory effects of [6]-gingerol, a major pungent principle of ginger, on phorbol ester-induced inflammation, epidermal ornithine decarboxylase activity and skin tumor promotion in ICR mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Capillary Permeability; Catechols; Curcumin; Epidermis; Fatty Alcohols; Female; Inflammation; Mice; Mice, Inbred ICR; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Plants, Medicinal; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1998 |
3 beta-p-hydroxybenzoyldehydrotumulosic acid from Poria cocos, and its anti-inflammatory effect.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Female; Inflammation; Japan; Medicine, Chinese Traditional; Mice; Mice, Inbred ICR; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plants, Medicinal; Tetradecanoylphorbol Acetate; Triterpenes | 1998 |
Further studies on anti-inflammatory activity of phycocyanin in some animal models of inflammation.
Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acid; Disease Models, Animal; Ear Diseases; Edema; Foot Diseases; Gossypium; Granuloma; Indomethacin; Inflammation; Lethal Dose 50; Male; Mice; Phycocyanin; Plant Proteins; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 1998 |
Endothelial cell "memory" of inflammatory stimulation: human venular endothelial cells store interleukin 8 in Weibel-Palade bodies.
Topics: Calcimycin; Cells, Cultured; Endothelium, Vascular; Golgi Apparatus; Histamine; Humans; Inflammation; Interleukin-1; Interleukin-8; Ionophores; Microscopy, Fluorescence; Microscopy, Immunoelectron; Organelles; Tetradecanoylphorbol Acetate; Umbilical Veins | 1998 |
Interference of myrtol standardized with inflammatory and allergic mediators.
Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Basophils; Cattle; Cyclohexanols; Dinoprostone; Drug Combinations; Drug Interactions; Eosinophils; Eucalyptol; Female; Guinea Pigs; Humans; Hyperemia; In Vitro Techniques; Inflammation; Leukemia, Basophilic, Acute; Leukotriene C4; Leukotriene D4; Leukotriene E4; Male; Mammary Glands, Animal; Menthol; Mice; Monoterpenes; Mucous Membrane; Muscle Contraction; Muscle, Smooth; Rats; Terpenes; Tetradecanoylphorbol Acetate; Trachea; Tumor Cells, Cultured | 1998 |
Functional responses of neonatal chicken and turkey heterophils following stimulation by inflammatory agonists.
Topics: Animals; Calcium; Cell Adhesion; Chickens; Immunity, Innate; Inflammation; Ionomycin; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Phagocytosis; Poultry Diseases; Respiratory Burst; Tetradecanoylphorbol Acetate; Turkeys | 1998 |
Production of proinflammatory cytokines by phorbol myristate acetate-treated THP-1 cells and monocyte-derived macrophages after phagocytosis of apoptotic CTLL-2 cells.
Topics: Animals; Apoptosis; Cell Differentiation; Cell Line; Cytokines; Humans; Inflammation; Interleukin-8; Macrophages; Mice; Monocytes; Oligopeptides; Phagocytosis; Phosphoserine; T-Lymphocytes, Cytotoxic; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1998 |
Corticosteroid-resistant bronchial asthma is associated with increased c-fos expression in monocytes and T lymphocytes.
Topics: Adrenal Cortex Hormones; Asthma; DNA-Binding Proteins; Drug Resistance; Female; Gene Expression; Genes, fos; Humans; Inflammation; Male; Middle Aged; Proto-Oncogene Proteins c-fos; Receptors, Glucocorticoid; Regulatory Sequences, Nucleic Acid; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription Factor AP-1 | 1998 |
Priming of human neutrophils by peroxynitrite: potential role in enhancement of the local inflammatory response.
Topics: Antioxidants; Blood Proteins; Calcium; Cells, Cultured; Humans; Inflammation; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitrates; Oxidants; Pyrimidines; Pyrrolidines; Stimulation, Chemical; Superoxides; Tetradecanoylphorbol Acetate; Tyrosine | 1999 |
Oxidation regulates the inflammatory properties of the murine S100 protein S100A8.
Topics: Animals; Antigens, Differentiation; Bronchoalveolar Lavage Fluid; Calcium-Binding Proteins; Calgranulin A; Chemotactic Factors; Cysteine; Dimerization; Disulfides; HL-60 Cells; Humans; Hypochlorous Acid; Inflammation; Leukocytes; Mass Spectrometry; Mice; Mutation; Oxidants; Peroxidase; Recombinant Proteins; Tetradecanoylphorbol Acetate | 1999 |
Topical antiinflammatory activity of phytosterols isolated from Eryngium foetidum on chronic and acute inflammation models.
Topics: Acute Disease; Administration, Topical; Animals; Anti-Inflammatory Agents; Caribbean Region; Chronic Disease; Edema; Female; Inflammation; Mice; Peroxidase; Phytosterols; Plants, Medicinal; Tetradecanoylphorbol Acetate | 1999 |
Regulation of human airway mucins by acrolein and inflammatory mediators.
Topics: Acrolein; Carcinoma, Mucoepidermoid; Dinoprostone; Gene Expression Regulation; Humans; Hydroxyeicosatetraenoic Acids; Inflammation; Kinetics; Lung Neoplasms; Mucin 5AC; Mucin-5B; Mucins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1999 |
Altered expression of interleukin-1 receptor antagonist in different stages of mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anthralin; Blotting, Northern; Blotting, Western; Carcinogens; Carcinoma, Squamous Cell; Cell Polarity; Cytoplasm; Disease Progression; Epidermis; Gene Expression Regulation, Neoplastic; Hyperplasia; Inflammation; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Keratinocytes; Mice; Mice, Inbred SENCAR; Neoplasm Proteins; Papilloma; Precancerous Conditions; RNA, Messenger; RNA, Neoplasm; Sialoglycoproteins; Skin Diseases; Skin Neoplasms; Tetradecanoylphorbol Acetate; Thapsigargin; Tumor Cells, Cultured | 1999 |
Inhibitory effects of caffeic acid phenethyl ester on the activity and expression of cyclooxygenase-2 in human oral epithelial cells and in a rat model of inflammation.
Topics: Air; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Arachidonic Acids; Caffeic Acids; Calcimycin; Carcinoma, Squamous Cell; Carrageenan; Cell Membrane; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Enzyme Activation; Enzyme Induction; Epithelial Cells; Genetic Vectors; Humans; Indomethacin; Inflammation; Ionophores; Isoenzymes; Male; Membrane Lipids; Membrane Proteins; Mouth Mucosa; Nucleopolyhedroviruses; Phenylethyl Alcohol; Phospholipids; Promoter Regions, Genetic; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred Lew; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1999 |
Differential regulation of tumor necrosing factor-alpha (TNF-alpha) and interleukin-10 (IL-10) secretion by protein kinase and phosphatase inhibitors in human alveolar macrophages.
Topics: Cells, Cultured; Enzyme Inhibitors; Gene Expression Regulation; Humans; Inflammation; Interleukin-10; Lipopolysaccharides; Macrophages, Alveolar; Marine Toxins; Oxazoles; Phosphoprotein Phosphatases; Protein Kinase C; Protein Kinase Inhibitors; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1999 |
Role of prostaglandin H synthase isoforms in murine ear edema induced by phorbol ester application on skin.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Cyclooxygenase 1; Cyclooxygenase 2; Dexamethasone; Ear Diseases; Edema; Eicosanoids; Inflammation; Isoenzymes; Male; Membrane Proteins; Mice; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Skin; Tetradecanoylphorbol Acetate; Time Factors | 1999 |
Release of neutrophil elastase and its role in tissue injury in acute inflammation: effect of the elastase inhibitor, FR134043.
Topics: Acute Disease; Animals; Benzoates; Capillary Permeability; Heterocyclic Compounds; Humans; Inflammation; Leukocyte Elastase; Lipopolysaccharides; Male; Mice; Neutrophils; Pyrrolidines; Rats; Rats, Sprague-Dawley; Serine Proteinase Inhibitors; Tetradecanoylphorbol Acetate | 1999 |
Constitutive protein expression of monocyte chemotactic protein-1 (MCP-1) by myelomonocytic cell lines and regulation of the secretion by anti- and proinflammatory stimuli.
Topics: Anti-Inflammatory Agents; Cell Differentiation; Chemokine CCL2; Enzyme-Linked Immunosorbent Assay; Humans; Inflammation; Leukemia, Myelomonocytic, Acute; Lipopolysaccharides; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1999 |
Overexpression of protein kinase C-alpha in the epidermis of transgenic mice results in striking alterations in phorbol ester-induced inflammation and COX-2, MIP-2 and TNF-alpha expression but not tumor promotion.
Topics: Abscess; Animals; Cattle; Chemokine CXCL2; Chemotactic Factors; Cyclooxygenase 2; Edema; Enzyme Activation; Epidermis; Gene Expression Regulation; Hair; Inflammation; Isoenzymes; Keratinocytes; Keratins; Mice; Mice, Transgenic; Monokines; Neutrophils; Promoter Regions, Genetic; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Protein Kinase C-alpha; RNA, Messenger; Skin; Skin Diseases; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Necrosis Factor-alpha | 1999 |
3-Geranyl-4-hydroxy-5-(3'-methyl-2'-butenyl)benzoic acid as an anti-inflammatory compound from Myrsine seguinii.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzoates; Edema; Inflammation; Magnetic Resonance Spectroscopy; Magnoliopsida; Mice; Plants, Medicinal; Terpenes; Tetradecanoylphorbol Acetate | 1999 |
Inflammatory mechanisms in Alzheimer's disease: inhibition of beta-amyloid-stimulated proinflammatory responses and neurotoxicity by PPARgamma agonists.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Astrocytes; Brain; Cell Differentiation; Chromans; Cyclooxygenase 2; Dinoprost; Genes, Reporter; Humans; Inflammation; Interleukin-6; Isoenzymes; Membrane Proteins; Mice; Mice, Inbred C57BL; Microbodies; Microglia; Monocytes; Peptide Fragments; Prostaglandin-Endoperoxide Synthases; Receptors, Cytoplasmic and Nuclear; Recombinant Proteins; Tetradecanoylphorbol Acetate; Thiazoles; Thiazolidinediones; Transcription Factors; Transfection; Troglitazone; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2000 |
Independent and combined effects of prolonged inhaled nitric oxide and oxygen on lung inflammation in newborn piglets.
Topics: Administration, Inhalation; Animals; Animals, Newborn; Antibodies, Monoclonal; Apoptosis; Catalase; CD18 Antigens; DNA; Female; Flow Cytometry; Hyperoxia; Immunohistochemistry; In Situ Nick-End Labeling; Inflammation; Lung; Male; Neutrophils; Nitric Oxide; Oxygen; Peroxidase; Random Allocation; Superoxide Dismutase; Swine; Tetradecanoylphorbol Acetate | 2000 |
The CD44-initiated pathway of T-cell extravasation uses VLA-4 but not LFA-1 for firm adhesion.
Topics: Animals; Cell Adhesion; Cell Movement; Endothelium, Vascular; Humans; Hyaluronan Receptors; Hyaluronic Acid; Inflammation; Integrin alpha4beta1; Integrins; Ionomycin; Lymphocyte Activation; Lymphocyte Function-Associated Antigen-1; Mice; Receptors, Lymphocyte Homing; Stress, Mechanical; T-Lymphocytes; Tetradecanoylphorbol Acetate; Vascular Cell Adhesion Molecule-1 | 2000 |
Inhibitory effect of euphol, a triterpene alcohol from the roots of Euphorbia kansui, on tumour promotion by 12-O-tetradecanoylphorbol-13-acetate in two-stage carcinogenesis in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Alcohols; Animals; Antihypertensive Agents; Carcinogens; Ear; Female; Inflammation; Lanosterol; Mice; Mice, Inbred ICR; Neoplasms, Experimental; Skin Neoplasms; Tetradecanoylphorbol Acetate; Triterpenes | 2000 |
Ceramide path in human lung cell death.
Topics: Apoptosis; Ceramides; Diglycerides; DNA Fragmentation; Enzyme Activation; Epithelial Cells; Humans; Hydrogen Peroxide; Hydrolysis; Inflammation; Lung; Membrane Lipids; Oxidative Stress; Protein Kinase C; Second Messenger Systems; Sphingomyelin Phosphodiesterase; Sphingomyelins; Sphingosine; Tetradecanoylphorbol Acetate | 2000 |
Study of eosinophil-endothelial adhesion, production of oxygen radicals and release of eosinophil cationic protein by peripheral blood eosinophils of patients with rheumatoid arthritis.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Autoimmune Diseases; Blood Proteins; Cell Adhesion; Cells, Cultured; Endothelium, Vascular; Eosinophil Granule Proteins; Eosinophils; Female; Humans; Inflammation; Interleukin-1; Macrophage-1 Antigen; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Reactive Oxygen Species; Ribonucleases; Tetradecanoylphorbol Acetate; Umbilical Cord | 1993 |
Coordinate activation of endogenous p38alpha, beta, gamma, and delta by inflammatory stimuli.
Topics: Antibodies, Monoclonal; Astrocytoma; Cell Line; Enzyme Activation; Escherichia coli; Humans; Inflammation; Interferon-gamma; Kinetics; Lipopolysaccharides; Mitogen-Activated Protein Kinase 12; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Recombinant Proteins; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured; U937 Cells | 2000 |
Inflammatory response following acute magnesium deficiency in the rat.
Topics: Acute-Phase Proteins; Animals; Animals, Newborn; Diet; Fibrinogen; Inflammation; Interleukin-6; Leukocytes; Liver; Macrophage Activation; Magnesium Deficiency; Male; Rats; Rats, Wistar; RNA, Messenger; Serum Albumin; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2000 |
Growth, adipose, brain, and skin alterations resulting from targeted disruption of the mouse peroxisome proliferator-activated receptor beta(delta).
Topics: Adipose Tissue; Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Constitution; Body Temperature; Brain; CD36 Antigens; Embryonic and Fetal Development; Fasting; Female; Hyperplasia; Inflammation; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Myelin Sheath; Receptors, Cytoplasmic and Nuclear; Skin; Sulindac; Tetradecanoylphorbol Acetate; Transcription Factors | 2000 |
In vivo activity of pseudoguaianolide sesquiterpene lactones in acute and chronic inflammation.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Female; Inflammation; Mice; Plants; Sesquiterpenes; Tetradecanoylphorbol Acetate | 2000 |
Cyclooxygenase regulates human oropharyngeal carcinomas via the proinflammatory cytokine IL-6: a general role for inflammation?
Topics: Animals; Antibodies; Arachidonic Acid; Cell Division; Clinical Trials, Phase II as Topic; Culture Media, Conditioned; Cyclooxygenase Inhibitors; Dinoprostone; DNA-Binding Proteins; Granulocyte-Macrophage Colony-Stimulating Factor; HL-60 Cells; Humans; Inflammation; Interleukin-1; Interleukin-6; Interleukin-8; Isoenzymes; Ketorolac; Mice; Mice, Inbred BALB C; Models, Biological; Oropharyngeal Neoplasms; Paracrine Communication; Prostaglandin-Endoperoxide Synthases; Receptors, Interleukin-6; RNA, Messenger; Signal Transduction; STAT3 Transcription Factor; Tetradecanoylphorbol Acetate; Trans-Activators; Tumor Cells, Cultured | 2000 |
Expression of angiopoietin-2 by human endometrial endothelial cells: regulation by hypoxia and inflammation.
Topics: Angiopoietin-1; Angiopoietin-2; Cell Hypoxia; Cells, Cultured; Endometrium; Endothelium, Vascular; Estradiol; Female; Gene Expression Regulation; Humans; Immunohistochemistry; Inflammation; Medroxyprogesterone; Membrane Glycoproteins; Neovascularization, Physiologic; Proteins; Receptor Protein-Tyrosine Kinases; Receptors, TIE; RNA, Messenger; Tetradecanoylphorbol Acetate | 2000 |
Biphasic regulation of leukocyte superoxide generation by nitric oxide and peroxynitrite.
Topics: Blotting, Western; DNA-Binding Proteins; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Enzyme Activation; Enzyme Inhibitors; Ferric Compounds; Flavonoids; Humans; Inflammation; Metalloporphyrins; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; NADPH Oxidases; Nerve Tissue Proteins; Neutrophils; Nitrates; Nitric Oxide; Oxygen; Phosphorylation; Receptors, Steroid; Receptors, Thyroid Hormone; Spin Trapping; Superoxides; Tetradecanoylphorbol Acetate; Time Factors | 2000 |
Relationship between TNF-alpha and iron metabolism in differentiating human monocytic THP-1 cells.
Topics: Binding Sites; Blotting, Northern; Cell Differentiation; Cell Line; Chelating Agents; Deferoxamine; Ferritins; Humans; Inflammation; Interferon-gamma; Iron; Leukemia, Monocytic, Acute; Macrophages; Receptors, Transferrin; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2000 |
Kurosu, a traditional vinegar produced from unpolished rice, suppresses lipid peroxidation in vitro and in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetic Acid; Animals; Antioxidants; Bepridil; Biphenyl Compounds; Edema; Female; Free Radical Scavengers; Free Radicals; Hydrogen Peroxide; Inflammation; Lipid Peroxidation; Mice; Mice, Inbred ICR; Oryza; Picrates; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Thiobarbituric Acid Reactive Substances; Time Factors; Vitamin E | 2000 |
Conjugation of arginine oligomers to cyclosporin A facilitates topical delivery and inhibition of inflammation.
Topics: Administration, Topical; Animals; Arginine; Biological Transport; Biotinylation; Cyclosporine; Cyclosporins; Humans; Inflammation; Interleukin-2; Ionomycin; Jurkat Cells; Mice; Mice, Inbred BALB C; Molecular Structure; Prodrugs; Skin; Skin Absorption; Tetradecanoylphorbol Acetate | 2000 |
Nitric oxide augments release of chemokines from monocytic U937 cells: modulation by anti-inflammatory pathways.
Topics: Chemokine CCL4; Chemokines; Cyclic AMP; Dexamethasone; Enzyme Inhibitors; Genistein; Humans; Imidazoles; Inflammation; Interleukin-8; Macrophage Inflammatory Proteins; Mitogen-Activated Protein Kinases; Monocytes; Nitric Oxide; Nitric Oxide Donors; p38 Mitogen-Activated Protein Kinases; Protein-Tyrosine Kinases; Pyridines; Signal Transduction; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta; Triazenes; U937 Cells | 2000 |
Effects of phycocyanin extract on prostaglandin E2 levels in mouse ear inflammation test.
Topics: Animals; Arachidonic Acid; Dinoprostone; Ear, External; Edema; Indicators and Reagents; Inflammation; Male; Mice; Phospholipases A; Phospholipases A2; Phycocyanin; Tetradecanoylphorbol Acetate | 2000 |
Involvement of peripheral polymorphonuclear leukocytes in oxidative stress and inflammation in type 2 diabetic patients.
Topics: Adult; Aged; Cell Survival; Diabetes Mellitus, Type 2; Female; Glutathione; Humans; Inflammation; Male; Middle Aged; Neutrophils; Oxidative Stress; Superoxides; Tetradecanoylphorbol Acetate | 2001 |
Production of interleukin-1 beta, interleukin-6 and tumor necrosis factor-alpha by a rat corneal epithelial cell line.
Topics: Animal Testing Alternatives; Animals; Carcinogens; Cell Line; Cornea; Cosmetics; Epithelial Cells; Inflammation; Inflammation Mediators; Interleukin-1; Interleukin-6; Lipopolysaccharides; Rats; Sensitivity and Specificity; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Wound Healing | 2000 |
Degranulation status of airway tissue eosinophils in mouse models of allergic airway inflammation.
Topics: Animals; Cell Degranulation; Cytoplasmic Granules; Disease Models, Animal; Eosinophils; Exocytosis; Humans; Hypersensitivity; In Vitro Techniques; Inflammation; Lung; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; N-Formylmethionine Leucyl-Phenylalanine; Nasal Septum; Ovalbumin; Peroxidases; Respiratory Mucosa; Tetradecanoylphorbol Acetate | 2001 |
Protein kinase C-alpha coordinately regulates cytosolic phospholipase A(2) activity and the expression of cyclooxygenase-2 through different mechanisms in mouse keratinocytes.
Topics: Animals; Arachidonic Acid; CCAAT-Enhancer-Binding Protein-beta; Cells, Cultured; Cyclooxygenase 2; Cytosol; Dinoprostone; Enzyme Inhibitors; Inflammation; Isoenzymes; Keratinocytes; Keratins; Mice; Mice, Transgenic; Mitogen-Activated Protein Kinase Kinases; Phospholipases A; Phospholipids; Phosphorylation; Promoter Regions, Genetic; Prostaglandin-Endoperoxide Synthases; Protein Isoforms; Protein Kinase C; Protein Kinase C-alpha; Signal Transduction; Skin; Tetradecanoylphorbol Acetate | 2001 |
Apolipoprotein A-I inhibits the production of interleukin-1beta and tumor necrosis factor-alpha by blocking contact-mediated activation of monocytes by T lymphocytes.
Topics: Acute-Phase Reaction; Adult; Animals; Apolipoprotein A-I; Cattle; Cell Communication; Depression, Chemical; Drug Design; Fetal Blood; Gene Expression Regulation; Humans; Infant, Newborn; Inflammation; Interleukin-1; Lipopolysaccharides; Lipoproteins, HDL; Mice; Monocytes; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2001 |
A catechol antioxidant protocatechuic acid potentiates inflammatory leukocyte-derived oxidative stress in mouse skin via a tyrosinase bioactivation pathway.
Topics: Animals; Antioxidants; Cell Survival; Dermatitis, Contact; Drug Synergism; Female; HL-60 Cells; Humans; Hydroxybenzoates; Inflammation; Leukocytes; Mice; Mice, Inbred ICR; Models, Biological; Monophenol Monooxygenase; Oxidative Stress; Skin; Tetradecanoylphorbol Acetate | 2001 |
Potential application of cytokine level measurement in corneal epithelium.
Topics: Animals; Carcinogens; Cell Line; Cytokines; Detergents; Enzyme-Linked Immunosorbent Assay; Epithelium, Corneal; Inflammation; Interleukin-1; Interleukin-6; Lipopolysaccharides; Octoxynol; Rats; Tetradecanoylphorbol Acetate; Time Factors; Tumor Necrosis Factor-alpha | 2001 |
Dipalmitoylphosphatidylcholine modulates inflammatory functions of monocytic cells independently of mitogen activated protein kinases.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Cell Line; Humans; Inflammation; Luminescent Measurements; MAP Kinase Signaling System; Membrane Lipids; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Monocytes; p38 Mitogen-Activated Protein Kinases; Phospholipids; Phosphorylation; Protein Processing, Post-Translational; Pulmonary Surfactants; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Zymosan | 2001 |
Suppression of 12-O-tetradecanoylphorbol-13-acetate-induced epidermal hyperplasia and inflammation by the dehydroepiandrosterone analog 16alpha-fluoro-5-androsten-17-one and its reversal by NADPH liposomes.
Topics: Androstenes; Animals; Antineoplastic Agents; Binding, Competitive; Capillary Permeability; Carcinogens; Cations; Corticosterone; Dehydroepiandrosterone; DNA; Epidermis; Female; Free Radicals; Hyperplasia; Inflammation; Liposomes; Mice; NADP; Tetradecanoylphorbol Acetate | 2001 |
Endothelial cell laminin isoforms, laminins 8 and 10, play decisive roles in T cell recruitment across the blood-brain barrier in experimental autoimmune encephalomyelitis.
Topics: Animals; Antibody Specificity; Basement Membrane; Blood-Brain Barrier; Brain; Cell Adhesion; Cells, Cultured; Chemotaxis, Leukocyte; Cytokines; Encephalomyelitis, Autoimmune, Experimental; Endothelium; Extracellular Matrix; Female; Inflammation; Laminin; Meninges; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Protein Isoforms; Receptors, Laminin; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate | 2001 |
Adenosine A2A receptor activation reduces proinflammatory events and decreases cell death following intracerebral hemorrhage.
Topics: Adenosine; Adenylyl Cyclases; Animals; Apoptosis; Cerebral Hemorrhage; Chemotaxis, Leukocyte; Humans; In Situ Nick-End Labeling; Inflammation; Injections, Intraventricular; Male; Neutrophils; Phenethylamines; Phytohemagglutinins; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Receptor, Adenosine A3; Receptors, Purinergic P1; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; U937 Cells | 2001 |
Inflammation-induced changes in serum modulate chicken macrophage function.
Topics: Animals; Cell Line; Chickens; Immunity, Cellular; In Vitro Techniques; Inflammation; Lipopolysaccharides; Macrophages; Male; Reactive Oxygen Species; Respiratory Burst; Tetradecanoylphorbol Acetate | 2001 |
The granzyme B inhibitor, PI-9, is present in endothelial and mesothelial cells, suggesting that it protects bystander cells during immune responses.
Topics: Ascitic Fluid; Cell Line; Cell Line, Transformed; Cells, Cultured; Endothelium; Epithelial Cells; Epithelium; Granzymes; Humans; Immunohistochemistry; Inflammation; RNA, Messenger; Serine Endopeptidases; Serine Proteinase Inhibitors; Serpins; Tetradecanoylphorbol Acetate; Up-Regulation | 2001 |
Chemiluminescence in inflammatory bowel disease patients: a parameter of inflammatory activity.
Topics: Adult; Blood Chemical Analysis; Case-Control Studies; Colitis, Ulcerative; Crohn Disease; Female; Humans; Inflammation; Luminescent Measurements; Luminol; Male; Middle Aged; Reactive Oxygen Species; Tetradecanoylphorbol Acetate | 2001 |
Anti-inflammatory planar chiral [2.2]paracyclophaneacetic acid enantiomers.
Topics: Acetates; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Edema; Female; Humans; Inflammation; Mice; Molecular Conformation; Oxazolone; Polycyclic Compounds; Rats; Rats, Wistar; Stereoisomerism; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 2001 |
Altered skin development and impaired proliferative and inflammatory responses in transgenic mice overexpressing the glucocorticoid receptor.
Topics: Animals; Cell Division; Ectoderm; Gene Expression; Inflammation; Keratin-15; Keratin-5; Keratins; Mice; Mice, Transgenic; Promoter Regions, Genetic; Receptors, Glucocorticoid; Skin; Tetradecanoylphorbol Acetate | 2001 |
N-pyridinyl-indole-3-(alkyl)carboxamides and derivatives as potential systemic and topical inflammation inhibitors.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Drug Design; Drug Evaluation, Preclinical; Ear, External; Edema; Indoles; Inflammation; Magnetic Resonance Spectroscopy; Male; Mice; Pyridines; Rats; Spectrophotometry, Infrared; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 2001 |
Human endothelial-cell specific molecule-1 binds directly to the integrin CD11a/CD18 (LFA-1) and blocks binding to intercellular adhesion molecule-1.
Topics: Biosensing Techniques; CD18 Antigens; Cell Adhesion; Cell Movement; Cell-Free System; Computer Systems; Endothelium, Vascular; Humans; Inflammation; Intercellular Adhesion Molecule-1; Jurkat Cells; Lymphocyte Activation; Lymphocyte Function-Associated Antigen-1; Neoplasm Proteins; Protein Binding; Protein Structure, Tertiary; Proteins; Proteoglycans; Temperature; Tetradecanoylphorbol Acetate | 2001 |
15-Deoxy-delta(12,14)-prostaglandin J2 is a negative regulator of macrophage functions.
Topics: Animals; Cell Adhesion; Chemotaxis; Escherichia coli; Hydrogen Peroxide; Inflammation; Ligands; Lipopolysaccharides; Macrophage-1 Antigen; Macrophages, Peritoneal; Male; Oxidative Stress; Peritonitis; Phagocytosis; Prostaglandin D2; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Superoxides; Tetradecanoylphorbol Acetate; Transcription Factors; Zymosan | 2001 |
Ebselen, a glutathione peroxidase mimetic seleno-organic compound, as a multifunctional antioxidant. Implication for inflammation-associated carcinogenesis.
Topics: Animals; Antioxidants; Azoles; Blotting, Western; Carcinogens; Cell Line; Cells, Cultured; Cyclooxygenase 2; Dose-Response Relationship, Drug; Edema; Epidermis; Glutathione Peroxidase; Glutathione Transferase; Hepatocytes; HL-60 Cells; Humans; Hydrogen Peroxide; Inflammation; Isoenzymes; Isoindoles; Leukocytes; Lipopolysaccharides; Liver; Membrane Proteins; Mice; Mice, Inbred ICR; Models, Chemical; NADH, NADPH Oxidoreductases; Organoselenium Compounds; Oxidative Stress; Prostaglandin-Endoperoxide Synthases; Rats; Superoxides; Tetradecanoylphorbol Acetate; Thiobarbituric Acid Reactive Substances; Time Factors | 2002 |
New insights into the mechanism of action of the anti-inflammatory triterpene lupeol.
Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acid; Cytokines; Dinoprostone; Dose-Response Relationship, Drug; Edema; Inflammation; Interleukin-1; Leukotriene C4; Macrophages, Peritoneal; Male; Mice; Models, Animal; Nitrites; Pentacyclic Triterpenes; Phytotherapy; Pimenta; Plant Extracts; Tetradecanoylphorbol Acetate; Triterpenes; Tumor Necrosis Factor-alpha | 2001 |
Critical roles of PPAR beta/delta in keratinocyte response to inflammation.
Topics: Animals; Apoptosis; Cell Differentiation; Ceramides; Dendritic Cells; Drug Resistance; Fibroblasts; Gene Deletion; In Situ Nick-End Labeling; Inflammation; Interferon-gamma; Keratinocytes; Mice; Mice, Mutant Strains; Promoter Regions, Genetic; Receptors, Cytoplasmic and Nuclear; Ribonucleases; Skin; Tetradecanoylphorbol Acetate; Transcription Factors; Tumor Necrosis Factor-alpha; Up-Regulation; Wound Healing | 2001 |
Induction of cyclooxygenase-2 by tumor promoters in transformed and cytochrome P450 2E1-expressing hepatocytes.
Topics: Animals; Blotting, Western; Carcinogens; CCAAT-Enhancer-Binding Proteins; Cell Line, Transformed; Cell Transformation, Neoplastic; Chenodeoxycholic Acid; Cyclooxygenase 2; Cytochrome P-450 CYP2E1; Electrophoretic Mobility Shift Assay; Enzyme Induction; Hepatocytes; Inflammation; Isoenzymes; Mitogen-Activated Protein Kinases; NF-kappa B; Phosphatidylinositol 3-Kinases; Prostaglandin-Endoperoxide Synthases; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate | 2002 |
Screening of edible Japanese plants for suppressive effects on phorbol ester-induced superoxide generation in differentiated HL-60 cells and AS52 cells.
Topics: Allopurinol; Animals; Antioxidants; Carcinogens; Cell Differentiation; Cell Line; Cricetinae; Dose-Response Relationship, Drug; Enzyme Inhibitors; HL-60 Cells; Humans; Inflammation; NADPH Oxidases; Oxidative Stress; Oxygen; Phorbol Esters; Plant Extracts; Superoxides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Xanthine Oxidase | 2002 |
Resident skin-specific gammadelta T cells provide local, nonredundant regulation of cutaneous inflammation.
Topics: Animals; Dendritic Cells; Dermatitis; Genes, Recessive; Genes, T-Cell Receptor delta; Inflammation; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Knockout; Receptors, Antigen, T-Cell, gamma-delta; Skin; T-Lymphocytes; Tetradecanoylphorbol Acetate | 2002 |
Anti-inflammatory triterpenes from Pistacia terebinthus galls.
Topics: Animals; Anti-Inflammatory Agents; Calcimycin; Cyproheptadine; Dexamethasone; Dose-Response Relationship, Drug; Hindlimb; Inflammation; Ionophores; Leukotriene B4; Magnetic Resonance Spectroscopy; Mice; Neutrophils; Phospholipases A; Phospholipases A2; Pistacia; Plant Extracts; Tetradecanoylphorbol Acetate; Triterpenes | 2002 |
Potentiation by human serum of anti-inflammatory cytokine production by human macrophages in response to apoptotic cells.
Topics: Antibodies, Monoclonal; Apoptosis; Cell Line; Down-Regulation; Humans; Immunoglobulin Fab Fragments; Immunoglobulin G; Inflammation; Interleukin-10; Interleukin-2; Interleukin-8; Macrophages; Phagocytosis; Receptors, IgG; Recombinant Proteins; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta | 2002 |
Constitutive activation of peroxisome proliferator-activated receptor-gamma suppresses pro-inflammatory adhesion molecules in human vascular endothelial cells.
Topics: Cells, Cultured; DNA; E-Selectin; Endothelium, Vascular; Humans; Inflammation; Intercellular Adhesion Molecule-1; NF-kappa B; Promoter Regions, Genetic; Receptors, Cytoplasmic and Nuclear; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription Factors; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1 | 2002 |
Inflammatory, tumor initiating and promoting activities of polycyclic aromatic hydrocarbons and diterpene esters in mouse skin as compared with their prostaglandin releasing potency in vitro.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Diterpenes; Dose-Response Relationship, Drug; In Vitro Techniques; Inflammation; Macrophages; Mice; Polycyclic Compounds; Precancerous Conditions; Prostaglandins E; Skin; Tetradecanoylphorbol Acetate; Time Factors | 1978 |
Quantitative correlation between in vitro and in vivo activities of phorbol esters.
Topics: Animals; Cell Survival; Cells, Cultured; Deoxy Sugars; Deoxyglucose; Dose-Response Relationship, Drug; Fibroblasts; Glycoproteins; Inflammation; Mice; Myristic Acids; Phorbol Esters; Phorbols; Tetradecanoylphorbol Acetate | 1979 |
An assay procedure for the comparative irritancy testing of esters in the tigliane and daphnane series.
Topics: Animals; Chemical Phenomena; Chemistry; Diterpenes; Esters; Female; Inflammation; Irritants; Mice; Phorbols; Plants, Toxic; Skin; Tetradecanoylphorbol Acetate; Toxins, Biological | 1979 |
Epidermal cell proliferation and promoting ability of phorbol esters.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Division; Dose-Response Relationship, Drug; Drug Synergism; Edema; Female; Hyperplasia; Inflammation; Mice; Neoplasms, Experimental; Papilloma; Phorbol Esters; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1976 |
ONO-4057, a novel, orally active leukotriene B4 antagonist: effects on LTB4-induced neutrophil functions.
Topics: Animals; Calcium; Cell Aggregation; Chemotaxis, Leukocyte; Complement C5a; Cytoplasmic Granules; Guinea Pigs; Humans; Inflammation; Leukotriene B4; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutropenia; Neutrophils; Phenylpropionates; Receptors, Immunologic; Receptors, Leukotriene B4; Tetradecanoylphorbol Acetate | 1992 |
Activation of HLA-DR and interleukin-6 gene transcription in resting T cells via the CD2 molecule: relevance to chronic immune-mediated inflammation.
Topics: Antigens, Differentiation, T-Lymphocyte; CD2 Antigens; Cells, Cultured; Flow Cytometry; Gene Expression Regulation; HLA-DR Antigens; Humans; Immunity, Cellular; Inflammation; Interleukin-6; Leucine; Lymphocyte Activation; Phytohemagglutinins; Receptors, Immunologic; Receptors, Interleukin-2; RNA, Messenger; Rosette Formation; T-Lymphocytes; Tetradecanoylphorbol Acetate; Time Factors; Transcription, Genetic; Up-Regulation | 1992 |
The rat c-kit ligand, stem cell factor, induces c-kit receptor-dependent mouse mast cell activation in vivo. Evidence that signaling through the c-kit receptor can induce expression of cellular function.
Topics: Animals; Bone Marrow Transplantation; CHO Cells; Cricetinae; Escherichia coli; Fibrin; Hematopoietic Cell Growth Factors; Inflammation; Mast Cells; Mice; Mice, Inbred Strains; Mice, Mutant Strains; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-kit; Rats; Receptors, Cell Surface; Recombinant Proteins; Signal Transduction; Stem Cell Factor; Tetradecanoylphorbol Acetate | 1992 |
Novel inhibitor of phospholipase A2 with topical anti-inflammatory activity.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Platelets; Dose-Response Relationship, Drug; Edema; Humans; Inflammation; Kinetics; Mice; Molecular Structure; Phospholipases A; Phospholipases A2; Tetradecanoylphorbol Acetate; Tretinoin | 1992 |
Expression of 92 kDa phagocyte gelatinase by inflammatory and connective tissue cells.
Topics: Cell Differentiation; Collagenases; Connective Tissue; Enzyme Induction; Fibroblasts; Humans; Inflammation; Leukemia, Monocytic, Acute; Leukemia, Promyelocytic, Acute; Macrophages, Alveolar; Matrix Metalloproteinase 9; Molecular Weight; Monocytes; Neoplasm Proteins; Neutrophils; Phagocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
Gomisin A inhibits tumor promotion by 12-O-tetradecanoylphorbol-13-acetate in two-stage carcinogenesis in mouse skin.
Topics: Animals; Anticarcinogenic Agents; Cyclooctanes; Dioxoles; Drugs, Chinese Herbal; Female; Inflammation; Lignans; Mice; Mice, Inbred ICR; Polycyclic Compounds; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1992 |
Expression of tissue factor pathway inhibitor by cultured endothelial cells in response to inflammatory mediators.
Topics: Animals; Base Sequence; Blood; Blotting, Northern; Cattle; Cell Line; Cells, Cultured; Endothelium, Vascular; Endotoxins; Factor VII; Gene Expression; Humans; Inflammation; Interleukin-1; Lipoproteins; Liver; Lung; Molecular Sequence Data; Rabbits; RNA, Messenger; Tetradecanoylphorbol Acetate; Thromboplastin; Tumor Necrosis Factor-alpha; Umbilical Veins | 1992 |
Eosinophil activation on biologic surfaces. Production of O2- in response to physiologic soluble stimuli is differentially modulated by extracellular matrix components and endothelial cells.
Topics: Endothelium, Vascular; Eosinophils; Extracellular Matrix; Humans; In Vitro Techniques; Inflammation; Lipopolysaccharides; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Substance P; Superoxides; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1991 |
The main serum protease inhibitors; alpha-1-proteinase inhibitor and alpha-2-macroglobulin inhibit H2O2 release from human polymorphonuclear leukocytes stimulated with phorbol myristate acetate.
Topics: alpha 1-Antitrypsin; alpha-Macroglobulins; Dianisidine; Emphysema; Humans; Hydrogen Peroxide; In Vitro Techniques; Inflammation; Neutrophils; Tetradecanoylphorbol Acetate | 1991 |
Periprosthetic chronic inflammation characterized through the measurement of superoxide anion production by synovial-derived macrophages.
Topics: Adult; Aged; Bone Resorption; Hip Prosthesis; Humans; Inflammation; Macrophages; Middle Aged; Prosthesis Failure; Reoperation; Superoxides; Synovial Fluid; Tetradecanoylphorbol Acetate | 1991 |
Serum amyloid A (SAA3) produced by rabbit synovial fibroblasts treated with phorbol esters or interleukin 1 induces synthesis of collagenase and is neutralized with specific antiserum.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cells, Cultured; Cloning, Molecular; DNA; DNA-Binding Proteins; Enzyme Induction; Fibroblasts; Immunologic Techniques; Inflammation; Interleukin-1; Microbial Collagenase; Molecular Sequence Data; Proto-Oncogene Proteins c-jun; Rabbits; Serum Amyloid A Protein; Synovial Membrane; Tetradecanoylphorbol Acetate; Time Factors; Transcription Factors | 1991 |
Effect of dietary fish oil on development and selected functions of murine inflammatory macrophages.
Topics: Administration, Oral; Animals; Cell Adhesion; Cell Movement; Cells, Cultured; Dietary Fats, Unsaturated; Dose-Response Relationship, Drug; Female; Fish Oils; Histocompatibility Antigens Class II; Inflammation; Interferon-gamma; Lipopolysaccharides; Macrophages; Mice; Peroxides; Phagocytosis; Safflower Oil; Tetradecanoylphorbol Acetate; Zymosan | 1991 |
Inhibitory effects of new types of biflavonoid-related polyphenols; lophirone A and lophiraic acid, on some tumor promoter-induced biological responses in vitro and in vivo.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzopyrans; Cocarcinogenesis; Enzyme Activation; Female; Flavonoids; Inflammation; Male; Mice; Mice, Inbred ICR; Papilloma; Phenols; Polymers; Protein Kinase C; Rats; Rats, Inbred WKY; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1991 |
The role of chronic acanthosis and subacute inflammation in tumor promotion in CD-1 mice by petroleum middle distillates.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acanthosis Nigricans; Administration, Topical; Animals; Body Weight; Carcinogens; Chronic Disease; Cocarcinogenesis; Dexamethasone; Dose-Response Relationship, Drug; Inflammation; Kerosene; Male; Mice; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1991 |
Stimulation of in vivo tumor growth and phorbol ester-induced inflammation by N,N-diethyl-2-[4-(phenylmethyl)phenoxy] ethanamine HCl, a potent ligand for intracellular histamine receptors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Division; Drug Synergism; Epithelium; Female; Histamine Antagonists; Hyperplasia; Inflammation; Leukemia L5178; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred DBA; Mitotic Index; Phenyl Ethers; Rats; Rats, Inbred Strains; Receptors, Histamine; Skin; Tetradecanoylphorbol Acetate | 1991 |
Relative inhibitory activity of berberine-type alkaloids against 12-O-tetradecanoylphorbol-13-acetate-induced inflammation in mice.
Topics: Alkaloids; Animals; Anti-Inflammatory Agents, Non-Steroidal; Berberine; Female; Inflammation; Mice; Mice, Inbred ICR; Tetradecanoylphorbol Acetate | 1991 |
Ionizing radiation at low doses induces inflammatory reactions in human blood.
Topics: Arachidonic Acid; Blood; Blood Cells; Calcimycin; Dose-Response Relationship, Radiation; Escherichia coli; Gamma Rays; Humans; Inflammation; Luminescent Measurements; Luminol; N-Formylmethionine Leucyl-Phenylalanine; Phospholipases A; Phospholipases A2; Radiation Dosage; Respiratory Burst; Saponins; Tetradecanoylphorbol Acetate | 1991 |
Inflammation of guinea pig dermis. Effects of leukotriene B4 receptor antagonist, SC-41930.
Topics: Administration, Cutaneous; Animals; Benzopyrans; Calcimycin; Disease Models, Animal; Guinea Pigs; Inflammation; Male; Psoriasis; Receptors, Immunologic; Receptors, Leukotriene B4; Skin; Tetradecanoylphorbol Acetate | 1990 |
CD18-dependent and -independent mechanisms of neutrophil emigration in the pulmonary and systemic microcirculation of rabbits.
Topics: Animals; Antibodies, Monoclonal; Antigen-Antibody Reactions; Bronchi; Bronchoalveolar Lavage Fluid; CD18 Antigens; Cell Movement; Endotoxins; Escherichia coli; Immunologic Techniques; Inflammation; Lung; Microcirculation; Neutrophils; Pulmonary Alveoli; Rabbits; Receptors, Leukocyte-Adhesion; Streptococcus pneumoniae; Tetradecanoylphorbol Acetate | 1990 |
Evidence that a receptor-operated event on the neutrophil mediates neutrophil accumulation in vivo. Pretreatment of 111In-neutrophils with pertussis toxin in vitro inhibits their accumulation in vivo.
Topics: Animals; CD18 Antigens; Cell Adhesion; Cell Aggregation; Cell Degranulation; Complement C5a; Inflammation; Interleukin-1; Interleukin-8; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Rabbits; Receptors, Leukocyte-Adhesion; Recombinant Proteins; Skin; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella; Zymosan | 1990 |
Inhibitory effects of azelastine on superoxide anion generation from activated inflammatory cells measured by a simple chemiluminescence method.
Topics: Animals; Cytochalasin B; Eosinophils; Histamine H1 Antagonists; Humans; In Vitro Techniques; Inflammation; Luminescent Measurements; Male; Mast Cells; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; p-Methoxy-N-methylphenethylamine; Phthalazines; Rats; Rats, Inbred Strains; Superoxides; Tetradecanoylphorbol Acetate | 1990 |
An inducible 50-kilodalton NF kappa B-like protein and a constitutive protein both bind the acute-phase response element of the angiotensinogen gene.
Topics: Acute-Phase Reaction; Angiotensinogen; Animals; Base Sequence; Cycloheximide; DNA Mutational Analysis; DNA-Binding Proteins; Gene Expression Regulation, Enzymologic; Genes; In Vitro Techniques; Inflammation; Lipopolysaccharides; Molecular Sequence Data; Molecular Weight; Nuclear Proteins; Rats; Regulatory Sequences, Nucleic Acid; Tetradecanoylphorbol Acetate; Transcription Factors; Transcription, Genetic | 1990 |
Effects of antihistamines on phorbol ester tumor promotion and vascular permeability changes.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Capillary Permeability; Cimetidine; Diphenhydramine; Female; Indomethacin; Inflammation; Masoprocol; Mice; Mice, Inbred Strains; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1990 |
FPL 62064, a topically active 5-lipoxygenase/cyclooxygenase inhibitor.
Topics: Administration, Cutaneous; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antigen-Antibody Complex; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Carrageenan; Cyclooxygenase Inhibitors; Eicosanoids; Female; Guinea Pigs; Humans; In Vitro Techniques; Inflammation; Lipoxygenase Inhibitors; Mice; Neutrophils; Prostaglandin D2; Pyrazoles; Rabbits; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 1990 |
Biochemical and pharmacological properties of a new topical anti-inflammatory compound, 9-phenylnonanohydroxamic acid (BMY 30094).
Topics: Administration, Cutaneous; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 12-Lipoxygenase; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Arachidonic Acids; Carrageenan; Chromatography, High Pressure Liquid; Eicosanoids; Exudates and Transudates; Female; Hydroxamic Acids; Inflammation; Male; Mice; Molecular Structure; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1990 |
"Autoregulation" of human neutrophil activation in vitro: regulation of phorbol myristate acetate-induced neutrophil activation by cell density.
Topics: Arachidonic Acid; Arachidonic Acids; Cell Count; Cell Membrane; Flow Cytometry; Homeostasis; Humans; Hydrogen Peroxide; Inflammation; Microscopy, Electron; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate | 1990 |
Antitumor promotion and antiinflammation: down-modulation of AP-1 (Fos/Jun) activity by glucocorticoid hormone.
Topics: Animals; Base Sequence; Cell Line; Dexamethasone; DNA-Binding Proteins; Enhancer Elements, Genetic; Gene Expression Regulation, Enzymologic; HeLa Cells; Humans; Inflammation; Kinetics; Microbial Collagenase; Molecular Sequence Data; Oligonucleotide Probes; Promoter Regions, Genetic; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-jun; Proto-Oncogenes; Tetradecanoylphorbol Acetate; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transfection | 1990 |
Epithelial macrophages secrete a deactivating factor for superoxide release.
Topics: Animals; Biological Factors; Cells, Cultured; Female; Granuloma; Hypersensitivity, Delayed; Inflammation; Kinetics; Macrophages; Male; Mice; Oxidation-Reduction; Superoxides; Tetradecanoylphorbol Acetate; Time Factors | 1990 |
Dipyridamole inhibits O2- release and expression of tissue factor activity by peripheral blood monocytes stimulated with lipopolysaccharide.
Topics: Biological Transport; Cells, Cultured; Depression, Chemical; Dipyridamole; Endotoxins; Fibrinolytic Agents; Glucose; Humans; Inflammation; Leukocytes, Mononuclear; Lipopolysaccharides; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate; Thromboplastin | 1990 |
Neutrophil beta-2 microglobulin: an inflammatory mediator.
Topics: Adolescent; beta 2-Microglobulin; Cell Membrane; Cell Separation; Cytoplasmic Granules; Exocytosis; Humans; Immunoelectrophoresis, Two-Dimensional; Inflammation; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peptide Hydrolases; Subcellular Fractions; Tetradecanoylphorbol Acetate | 1990 |
Antiinflammatory reactivity of copper(I)-thionein.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Proteins; Chemical and Drug Induced Liver Injury; Ficusin; Free Radicals; Inflammation; Injections, Intraperitoneal; L-Iditol 2-Dehydrogenase; Male; Metallothionein; Mice; NADP; Neutrophils; Oxygen; Phagocytosis; Singlet Oxygen; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 1990 |
Cooperative interaction of nuclear factor-kappa B- and cis-regulatory enhancer binding protein-like factor binding elements in activating the interleukin-8 gene by pro-inflammatory cytokines.
Topics: Base Sequence; CCAAT-Enhancer-Binding Proteins; Cell Line; Cell Nucleus; Cytokines; DNA-Binding Proteins; Enhancer Elements, Genetic; Exons; Gene Expression Regulation; Humans; Inflammation; Interleukin-1; Interleukin-8; Molecular Sequence Data; Mutagenesis, Site-Directed; NF-kappa B; Nuclear Proteins; Oligonucleotide Probes; Recombinant Proteins; Tetradecanoylphorbol Acetate; Transfection; Tumor Necrosis Factor-alpha | 1990 |
Effects of the tumor promoter 12-O-tetradecanoylphorbol 13-acetate on peroxisomal activities and enzyme activities involved in lipid metabolism in rat liver.
Topics: Animals; Body Weight; Carcinogens; Electrophoresis, Polyacrylamide Gel; Inflammation; Lipid Metabolism; Liver; Male; Microbodies; Microsomes, Liver; Mitochondria, Liver; Organ Size; Proteins; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1990 |
Effect of resiniferatoxin pretreatment on the inflammatory response to phorbol-12-myristate-13-acetate in mouse strains with different susceptibilities to phorbol ester tumor promotion.
Topics: Animals; Carcinogens; Diterpenes; Edema; Female; Inflammation; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred Strains; Tetradecanoylphorbol Acetate; Time Factors | 1990 |
Monocyte adherence results in selective induction of novel genes sharing homology with mediators of inflammation and tissue repair.
Topics: Amino Acid Sequence; Antigen-Antibody Complex; Base Sequence; Blotting, Northern; Blotting, Southern; Cell Adhesion; Cloning, Molecular; Collagen; DNA; Endothelium, Vascular; Extracellular Matrix; Fibronectins; Gene Expression; Gene Library; Humans; Inflammation; Lipopolysaccharides; Molecular Sequence Data; Monocytes; Plastics; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors | 1990 |
Inflammatory cerebrospinal fluid T cells have activation requirements characteristic of CD4+CD45RA- T cells.
Topics: Antigens, Differentiation; Antigens, Differentiation, T-Lymphocyte; CD2 Antigens; CD4 Antigens; Cerebrospinal Fluid; Humans; Inflammation; Integrin beta1; Interleukin-2; Leukocyte Common Antigens; Lymphocyte Activation; Receptors, Immunologic; Receptors, Interleukin-2; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1989 |
Effect of a 5-lipoxygenase (5-LO)/cyclooxygenase (CO) inhibitor, WY-47, 288, on cutaneous models of inflammation.
Topics: Animals; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Cyclooxygenase Inhibitors; Disease Models, Animal; Ear; Erythema; Female; Guinea Pigs; Inflammation; Lipoxygenase Inhibitors; Mice; Naphthalenes; Quinolines; Radiation Injuries; Salicylates; Skin; Skin Diseases; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 1989 |
Model systems for defining initiation, promotion, and progression of skin neoplasms.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogenicity Tests; Cell Division; Cocarcinogenesis; Cricetinae; Disease Models, Animal; Hyperplasia; Inflammation; Mesocricetus; Mice; Mutagenicity Tests; Neoplasms, Radiation-Induced; Salmonella typhimurium; Skin; Skin Neoplasms; Solvents; Species Specificity; Tetradecanoylphorbol Acetate; Turpentine; Ultraviolet Rays | 1989 |
Characterization of the oxidant generation by inflammatory cells lavaged from rat lungs following acute exposure to ozone.
Topics: Animals; Atmosphere Exposure Chambers; Inflammation; Luminescent Measurements; Lung; Male; Oxygen; Ozone; Peroxidase; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1989 |
Differential inhibition by staurosporine, a potent protein kinase C inhibitor, of 12-O-tetradecanoylphorbol-13-acetate-caused skin tumor promotion, epidermal ornithine decarboxylase induction, hyperplasia and inflammation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alkaloids; Animals; Edema; Enzyme Induction; Female; Hyperplasia; Inflammation; Kinetics; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; Protein Kinase C; Reference Values; Skin; Skin Neoplasms; Staurosporine; Superoxides; Tetradecanoylphorbol Acetate | 1989 |
Pharmacological demonstration of inflammatory mediators using experimental inflammatory models: rat pleurisy induced by carrageenin and phorbol myristate acetate.
Topics: Animals; Capillary Permeability; Carrageenan; Disease Models, Animal; Epoprostenol; Guinea Pigs; Inflammation; Kinins; Platelet Activating Factor; Pleurisy; Prostaglandins; Rabbits; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Time Factors | 1989 |
Effect of chemical constituents from plants on 12-O-tetradecanoylphorbol-13-acetate-induced inflammation in mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Female; Inflammation; Mice; Mice, Inbred ICR; Plants; Tetradecanoylphorbol Acetate | 1989 |
Human monocyte inflammatory mediator gene expression is selectively regulated by adherence substrates.
Topics: Antigens, Surface; Cell Adhesion; Cell Adhesion Molecules; Cells, Cultured; Colony-Stimulating Factors; Culture Media; Extracellular Matrix; Gene Expression Regulation; Humans; Inflammation; Monocytes; Muramidase; Protein Synthesis Inhibitors; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1989 |
Neurogenic component of phorbol ester-induced mouse skin inflammation.
Topics: Administration, Topical; Animals; Diterpenes; Dose-Response Relationship, Drug; Erythema; Female; Hyperplasia; Inflammation; Mice; Mice, Inbred Strains; Phorbol Esters; Skin; Terpenes; Tetradecanoylphorbol Acetate | 1989 |
Potential regulatory role of inflammatory cells on local vascular smooth muscle tone.
Topics: Animals; Aorta, Thoracic; Exudates and Transudates; Guinea Pigs; In Vitro Techniques; Inflammation; Macrophages; Male; Muscle Relaxation; Muscle Tonus; Muscle, Smooth, Vascular; Neutrophils; Rats; Tetradecanoylphorbol Acetate | 1989 |
Oxidant-dependent metabolic activation of polycyclic aromatic hydrocarbons by phorbol ester-stimulated human polymorphonuclear leukocytes: possible link between inflammation and cancer.
Topics: Azides; Benzopyrenes; Biotransformation; Dihydroxydihydrobenzopyrenes; DNA; Humans; Inflammation; Luminescent Measurements; Mutation; Neutrophils; Oxidation-Reduction; Peroxidase; Salicylates; Superoxides; Tetradecanoylphorbol Acetate | 1985 |
Experimental pulmonary inflammatory injury in the monkey.
Topics: alpha 1-Antitrypsin; Animals; Blood Proteins; Humans; Inflammation; Lung Diseases; Macaca mulatta; Oligopeptides; Peptide Hydrolases; Peptidyl-Dipeptidase A; Protease Inhibitors; Pulmonary Alveoli; SRS-A; Tetradecanoylphorbol Acetate; Therapeutic Irrigation | 1985 |
Spontaneous tumor cytolysis mediated by inflammatory neutrophils: dependence upon divalent cations and reduced oxygen intermediates.
Topics: Animals; Calcium; Cytotoxicity, Immunologic; Edetic Acid; Egtazic Acid; Female; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Inflammation; Magnesium; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Neutrophils; Nitroblue Tetrazolium; Oxygen; Peroxidase; Superoxides; Tetradecanoylphorbol Acetate | 1986 |
Macrophage activation in rat models of inflammation and arthritis: determination of markers of stages of activation.
Topics: Animals; Arthritis; Arthritis, Experimental; Cytotoxicity, Immunologic; Dinoprostone; Inflammation; Interferon-gamma; Interleukin-1; Lipopolysaccharides; Macrophage Activation; Macrophages; Male; Phagocytosis; Prostaglandins E; Rats; Rats, Inbred Lew; Superoxides; Tetradecanoylphorbol Acetate | 1986 |
Analysis of tumor-promoter-induced inflammation in rats: participation of histamine and prostaglandin E2.
Topics: Animals; Capillary Permeability; Dinoprostone; Edema; Histamine; Indomethacin; Inflammation; Lyngbya Toxins; Methysergide; Neutrophils; Prostaglandins E; Pyrilamine; Rats; Tetradecanoylphorbol Acetate | 1987 |
Inhibition of phospholipase A2 (PLA2) activity by nifedipine and nisoldipine is independent of their calcium-channel-blocking activity.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcium Channel Blockers; Carbon Radioisotopes; Dose-Response Relationship, Drug; Humans; Inflammation; Macrophages; Male; Mice; Nifedipine; Nisoldipine; Peritoneal Cavity; Phospholipases; Phospholipases A; Phospholipases A2; SRS-A; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 1987 |
Inflammation, oxidative DNA damage, and carcinogenesis.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; DNA Damage; Hydrogen Peroxide; Inflammation; Macrophage Activation; Macrophages; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Oxidation-Reduction; Tetradecanoylphorbol Acetate | 1987 |
Effect of flavonoids on tumor promoter's activity.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Carcinogens; Cocarcinogenesis; Flavonoids; Inflammation; Mice; Mice, Inbred ICR; Tetradecanoylphorbol Acetate | 1988 |
[Epigenetic mechanism of tumor promotion. Interrelationship between inflammation and ornithine decarboxylase activity induced in vitro by the carcinogenic 12-O-tetradecanoyl-phorbol-13-acetate].
Topics: Animals; Dexamethasone; Epidermis; Female; Hyperplasia; Indomethacin; Inflammation; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; Skin Diseases; Tetradecanoylphorbol Acetate | 1988 |
Cyclosporine inhibits ornithine decarboxylase gene expression and acute inflammation in response to phorbol ester treatment of hairless mouse skin.
Topics: Animals; Cyclosporins; Depression, Chemical; Enzyme Induction; Inflammation; Mice; Mice, Hairless; Ornithine Decarboxylase; Skin; Tetradecanoylphorbol Acetate | 1988 |
The phenomenon of leukergy: induction and detection of leukocyte aggregation in whole human blood.
Topics: Adult; Aged; Antigen-Antibody Complex; Cell Aggregation; Complement C3; Complement C3a; Complement C5; Complement C5a, des-Arginine; Female; Humans; Inflammation; Lactoferrin; Leukocytes; Male; Middle Aged; Tetradecanoylphorbol Acetate; Zymosan | 1987 |
Early inflammatory changes in the skin of SENCAR and C57BL/6 mice following exposure to 12-O-tetradecanoylphorbol-13-acetate.
Topics: Animals; Capillary Permeability; Dose-Response Relationship, Drug; Edema; Female; Inflammation; Leukocytes; Mice; Mice, Inbred C57BL; Protein Kinase C; Skin; Skin Neoplasms; Species Specificity; Tetradecanoylphorbol Acetate | 1987 |
Role of inflammatory cells in the metabolic activation of polycyclic aromatic hydrocarbons in mouse skin.
Topics: Animals; Biotransformation; Dihydroxydihydrobenzopyrenes; DNA; Female; Inflammation; Mice; Neutrophils; Polycyclic Compounds; Skin; Tetradecanoylphorbol Acetate | 1987 |
Evidence for a role of the plasma kallikrein-kinin system in acute inflammation: reduced exudation during carrageenin- and kaolin-pleurisies in kininogen-deficient rats.
Topics: Acute Disease; Aging; Animals; Body Weight; Carrageenan; Inflammation; Kallikreins; Kaolin; Kininogens; Kinins; Organ Size; Pleurisy; Rats; Rats, Inbred Strains; Species Specificity; Tetradecanoylphorbol Acetate | 1986 |
Effect of capsaicin on croton oil and TPA induced tumorigenesis and inflammation.
Topics: Animals; Capsaicin; Croton Oil; Female; Inflammation; Mice; Neoplasms, Experimental; Tetradecanoylphorbol Acetate | 1986 |
Neutrophil-induced injury of rat pulmonary alveolar epithelial cells.
Topics: Animals; Cattle; Cell Adhesion; Cell Separation; Cell Survival; Endothelium; Epithelial Cells; Epithelium; Humans; Inflammation; Neutrophils; Pulmonary Alveoli; Rats; Tetradecanoylphorbol Acetate | 1986 |
Induction of megakaryocytic colony-stimulating activity in mouse skin by inflammatory agents and tumor promoters.
Topics: Animals; Betamethasone; Diterpenes; Dose-Response Relationship, Drug; Growth Substances; Inflammation; Megakaryocytes; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Skin; Skin Physiological Phenomena; Terpenes; Tetradecanoylphorbol Acetate; Thrombocytosis | 1987 |
Involvement of arachidonic acid metabolites in acute inflammation: detection of 6-keto-PGF1 alpha, thromboxane B2 and PGD2 in rat pleurisy induced by phorbol myristate acetate.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Chromatography, High Pressure Liquid; Inflammation; Male; Platelet Aggregation; Pleurisy; Prostaglandin D2; Prostaglandins D; Radioimmunoassay; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Thromboxane B2 | 1985 |