tetradecanoylphorbol acetate has been researched along with Hyperplasia in 232 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 89 (38.36) | 18.7374 |
| 1990's | 80 (34.48) | 18.2507 |
| 2000's | 34 (14.66) | 29.6817 |
| 2010's | 28 (12.07) | 24.3611 |
| 2020's | 1 (0.43) | 2.80 |
| Authors | Studies |
|---|---|
| Inoue, Y; Kiyoi, T; Kondo, H; Kurokawa, K; Nakada, Y; Nakajima, F; Sawa, M; Tsukamoto, T; Yokota, K; Yoshino, K | 1 |
| Dang, Y; Guo, C; Li, Y; Liang, Y; Liu, M; Shi, Y; Wang, C; Xiang, W; Xu, P; Ye, X; Zhang, X | 1 |
| Dahlhoff, M; Fröhlich, T; Goebeler, M; Hoesl, C; Hundt, JE; Kneitz, H; Schneider, MR; Wolf, R | 1 |
| Baek, M; DiGiovanni, J; Jang, IS; Kim, DJ; Kim, M; Lee, H; Morales, LD; Slaga, TJ | 1 |
| Ávila-Román, J; de Los Reyes, C; González-Rodríguez, ML; Motilva, V; Rabasco, AM; Rodríguez-Luna, A; Talero, E; Terencio, MDC | 1 |
| Liu, P; Wang, D | 1 |
| Li, Y; Liu, X; Lu, Y; Pei, B; Shen, W; Sun, D; Wang, X; Xiu, L; Xu, J; Yue, X; Zhang, X | 1 |
| Bernabeu, C; Del Castillo, G; Jerkic, M; Letarte, M; López-Novoa, JM; Martín-Villar, E; Pérez-Barriocanal, F; Pérez-Gómez, E; Prieto, M; Quintanilla, M | 1 |
| Hanausek, M; Junco, JJ; Kowalczyk, MC; Kowalczyk, P; Slaga, TJ; Sosnowska, R; Tolstykh, O; Walaszek, Z | 1 |
| Chen, L; Ghosh, S; Hayden, MS; Jimi, E; Pentland, AP; Poligone, B | 1 |
| DiGiovanni, J; Jiang, G; Kiguchi, K; Rho, O | 1 |
| Cline, JM; Endo, Y; Fonseca, LL; Ji, J; Lorenzo, PS; Rajani, C; Ramos, JW; Sharma, A; Stone, JC; Yanagida, JK | 1 |
| Arasa, J; Martos, P; Montesinos, MC; Terencio, MC; Valcuende-Cavero, F | 1 |
| Catapang, A; Dennis, EA; Dumlao, DS; Fischer, SM; Herschman, HR; Ishikawa, TO; Jiao, J; Magyar, CE; Mikulec, C; Norris, PC | 1 |
| Chen, C; Fan, F; Lin, C; Liu, Y; Liu, Z; Lu, Y; Shen, C; Sun, L; Tao, Y; Wang, A; Wang, S; Wei, Z; Wu, H; Zhao, L; Zhu, P; Zhu, Z | 1 |
| Brady, M; Brennan-Crispi, DM; Hossain, C; Mahoney, MG; Riobo, NA; Sahu, J | 1 |
| de Gruijl, F; Rebel, H; Tensen, K; van de Glind, G; van Kempen, M | 1 |
| Cheon, SA; Chung, JF; Joo, MY; Kim, B; Kim, KH; Lee, SJ; Park, SH; Park, TJ; Seo, ES; Sood, AK; Yang, JS; Yoon, CJ | 1 |
| Berx, G; Declercq, W; Denecker, G; Devos, M; Gilbert, B; Haigh, J; Hochepied, T; Lambert, J; Lemeire, K; Leurs, K; Libbrecht, L; Lippens, S; Mc Guire, C; Van Den Broecke, C; Vandenabeele, P; Vuylsteke, M | 1 |
| Bhattacharya, S; Bible, PW; Cataisson, C; Gormley, AC; Kellett, MD; Morasso, MI; Palazzo, E; Sun, HW; Yuspa, SH | 1 |
| Ala, U; Brusa, D; Calautti, E; Magnuson, MA; Neri, F; Oliviero, S; Provero, P; Riganti, C; Saoncella, S; Tassone, B | 1 |
| Afaq, F; Mukhtar, H; Sarfaraz, S; Siddiqui, IA; Syed, DN | 1 |
| Alam, MS; Athar, M; Chaudhary, SC; Siddiqui, MS | 1 |
| Barragan, DI; Charron, J; Dumesic, PA; Harada, K; Khavari, PA; Scholl, FA | 1 |
| Arthur, JS; Burns, CJ; Efimova, T; Gribben, EL; Hindes, A; Kissling, GE; Lin, MH; Longmore, GD; Owen, RJ; Schindler, EM; Yin, Y | 1 |
| Angel, P; Grabe, N; Hartenstein, B; Hess, J; Hildenbrand, M; Lahrmann, B; Rhiemeier, V | 1 |
| Chiba, K; Goto, M; Gusovsky, F; Inoue, Y; Ishii, N; Kuboi, Y; Muramoto, K; Omae, T; Shirota, H; Wang, YJ | 1 |
| Akase, T; Matsuda, T; Nagata, K; Sato, A; Shimada, M; Yamazoe, Y; Yoshinari, K | 1 |
| Jin, JY; Leshin, B; Lutfeali, S; Miliani de Marval, P; Selim, MA; Zhang, JY | 1 |
| Checkley, LA; DiGiovanni, J; Hursting, S; Moore, T; Rho, O | 1 |
| Aranda, A; Contreras-Jurado, C; García-Serrano, L; Gomez-Ferrería, MA; Paramio, JM; Segrelles, C | 1 |
| Hanausek, M; Junco, JJ; Kinjo, T; Kowalczyk, MC; Kowalczyk, P; Slaga, TJ; Tolstykh, O; Truong, H; Walaszek, Z | 1 |
| Brunton, VG; Kinnaird, A; Mason, S; Muir, M; Muller, WJ; Patel, H; Ridgway, RA; Sansom, OJ; Serrels, B | 1 |
| Chen, HD; He, CD; Liu, CH; Lu, T; Ma, GZ; Qiao, J; Wei, B; Wei, HC | 1 |
| Kawashima, Y; Kitajima, S; Mitsuoka, C; Ohara, M; Watanabe, H | 1 |
| Aiba, A; Chida, K; Hara, T; Hirai, T; Katsuki, M; Konishi, C; Kuroki, T; Nakamura, K; Nakao, K | 1 |
| Danø, K; Gårdsvoll, H; Hansen, LV; Jensen, ON; Lund, LR; Nielsen, BS; Ploug, M | 1 |
| Adhami, VM; Afaq, F; Mukhtar, H; Saleem, M | 1 |
| Collet, AM; Itoiz, ME; Molinari, B; Palmieri, M; Schwint, AE | 1 |
| Chimeno Zoth, SA; Collet, AM; Heber, E; Itoiz, ME; Schwint, AE | 1 |
| Afaq, F; Krueger, CG; Mukhtar, H; Reed, JD; Saleem, M | 1 |
| Chida, K; Hara, T; Hirai, T; Katsuki, M; Nakamura, K; Nakao, K; Saito, Y | 1 |
| Aarset, H; Andersen, S; Dai, HY; Ericsson, M; Krokan, HE; Nilsen, H; Peña-Diaz, J; Slupphaug, G | 1 |
| Chan, T; Fuhrman, J; Hansen, LA; Repertinger, S; Shafer, L | 1 |
| Berton, TR; Johnson, DG; Russell, JL; Weaks, RL | 1 |
| Fischer, SM; He, G; Sung, YM | 1 |
| Alters, W; Chaiswing, L; Li, Y; Oberley, TD; Verma, AK; Wheeler, DL | 1 |
| Fischer, SM; He, G; Hwang, DH; Sung, YM | 1 |
| Ha, HY; Kim, TY; Kim, Y; Ryoo, ZY | 1 |
| de Gruijl, FR; Hoogervorst, EM; Mulder, AM; Mullenders, LH; Nijhof, JG; Speksnijder, EN | 1 |
| Elomaa, O; Forsberg, S; Kainu, K; Kere, J; Puolakkainen, P; Rollman, O; Rozell, B; Saarialho-Kere, U; Suomela, S; Tammi, R; Tiala, I; Wakkinen, J | 1 |
| Amigó, M; Braza-Boïls, A; De Rosa, S; Payá, M; Terencio, MC | 1 |
| Chang, S; Demerjian, M; Elias, PM; Feingold, KR; Lee, SH; Man, M; Man, MQ; Shi, Y | 1 |
| Fujita, J; Sugawara, K; Tokuda, H; Yoshida, O | 1 |
| Iversen, OH | 1 |
| Astrup, EG; Iversen, OH | 2 |
| Engelhardt, DL; Laskin, JD; Mufson, RA; Piccinini, L; Weinstein, IB | 1 |
| Hasper, F; Müller, G; Schweizer, J | 1 |
| Schweizer, J | 1 |
| Klein-Szanto, AJ; Major, SK; Slaga, TJ | 1 |
| Bickenbach, JR; Mackenzie, IC | 1 |
| Nelson, KG; Slaga, TJ; Stephenson, KB | 1 |
| Nelson, KG; Slaga, TJ | 1 |
| Braun, SJ; Marko, M; Parsons, DF; Wansor, KJ | 1 |
| Emmerson, A; Parkinson, EK | 1 |
| Bryan, GT; Ertürk, E; Verma, AK | 1 |
| Argyris, TS | 8 |
| Fürstenberger, G; Marks, F; Seemann, D | 1 |
| Harris, RR; Mackenzie, IC | 1 |
| Fürstenberger, G; Marks, F | 1 |
| Boutwell, RK | 2 |
| Mascardo, RN; Sherline, P | 1 |
| Chiba, M; Conti, CJ; Klein-Szanto, AJ; Lee, SU; Thetford, D | 1 |
| Csuka, O; Sugár, J; Szentirmay, Z | 1 |
| Slaga, TJ | 1 |
| Berry, DL; Bertsch, S; Fürstenberger, G; Marks, F; Richter, H | 1 |
| Barrett, JC; Gray, T; Sisskin, EE | 1 |
| Fürstenberger, G; Marks, F; Sorg, B | 1 |
| Argyris, TS; Morris, R | 1 |
| Bowden, GT; Lockyer, JM; Magun, BE; Matrisian, LM | 1 |
| Bhisey, RA; Iyengar, B; Sirsat, SM | 1 |
| Hecker, E; Schmidt, R | 1 |
| Iversen, OH; Iversen, UM | 1 |
| Bourin, MC; Delescluse, C; Pruniéras, M | 1 |
| Fürstenberger, G; Ganss, M; Marks, F; Seemann, D | 1 |
| Iversen, OH; Paulsen, JE; Schjølberg, A | 1 |
| Marsh, WH; Parsa, I; Sutton, AL | 1 |
| Hasegawa, R; Imaida, K; Ito, N; Murasaki, G; Tatematsu, M | 1 |
| Barrett, JC; Sisskin, EE | 1 |
| Jenkinson, HF; McMillan, MD; Shearer, BH | 2 |
| Eckhardt, JN; Greenhalgh, DA; Roop, DR; Wang, XJ | 1 |
| Casatorres, J; Jorcano, JL; Navarro, JM | 1 |
| Chada, K; Conney, AH; D'Armiento, J; Dalal, SS; DiColandrea, T; Huang, MT; Okada, Y | 1 |
| Chida, K; Ikuta, T; Kuroki, T; Murakami, A; Tagawa, T | 1 |
| De Vries, GW; Garst, M; Harcourt, D; Lee, G; McLaughlin, A; Perez, J; Wenzel, MB; Wheeler, LA | 1 |
| Agarwal, R; Katiyar, SK; Korman, NJ; Mukhtar, H; Rupp, CO | 1 |
| Gimenez-Conti, IB; Slaga, TJ; Yoshimi, N | 1 |
| DiCunto, F; Dotto, GP; Escherick, JS; Flanders, KC; Missero, C | 1 |
| Conti, CJ; Robles, AI | 1 |
| Akhurst, RJ; Balmain, A; Bryson, S; Cousins, FM; Cui, W; Duffie, E; Fowlis, DJ | 1 |
| Ali, S; Dorn, GW | 1 |
| Fischer, SM; Maldve, RE | 1 |
| Chang, MC; Lee, MJ; Lin, JK; Wang, CJ | 1 |
| Eppley, RM; Hines, FA; Lambert, LA | 1 |
| Hansen, LA; Tennant, R | 1 |
| Fischer, SM; Lee, WY; Lockniskar, MF | 1 |
| Chang, RL; Conney, AH; Huang, MT; Lou, YR; Lu, YP; Newmark, HL; Reuhl, KR | 1 |
| Csuk-Glänzer, BI; Fürstenberger, G; Keppler, D; Marks, F | 1 |
| Meyer, SA; Monteiro-Riviere, NA; Moser, GJ; Smart, RC | 1 |
| Andringa, S; Baxter, CS; Miller, ML; Vasunia, KB | 1 |
| Bhisey, RA; Borges, AM; Ramchandani, AG | 1 |
| Conney, AH; Ferraro, T; Georgiadis, C; Ho, CT; Huang, MT; Laskin, JD; Lou, YR; Ma, W; Stauber, K; Wang, ZY | 1 |
| Ekström, T; Gimenez-Conti, I; Holmberg, B; Mild, KH; Rannug, A; Slaga, TJ | 2 |
| Frenkel, K; Wei, H; Wei, L | 1 |
| Agarwal, R; Ekker, S; Katiyar, SK; Mukhtar, H; Wood, GS | 1 |
| Beltrán, LM; DiGiovanni, J; Fujiki, H; Imamoto, A; Walker, SE; Wang, XJ | 1 |
| DiGiovanni, J; Imamoto, A; Kiguchi, K; Rupp, T; Xian, W; Zilberstein, A | 1 |
| Hennings, H; Li, L; Lowry, DT | 1 |
| Donehower, LA; Greenhalgh, DA; Roop, DR; Wang, XJ | 1 |
| Kamada, T; Kanazawa, T; Metoki, H; Oike, Y; Okuguchi, T; Onodera, K; Osanai, T | 1 |
| Reiners, JJ; Singh, KP | 1 |
| Budunova, IV; Carbajal, S; Kang, H; Slaga, TJ; Viaje, A | 1 |
| Beltrán, L; DiGiovanni, J; Dubowski, A; Kiguchi, K | 1 |
| Bol, DK; DiGiovanni, J; Gimenez-Conti, I; Kiguchi, K; Rupp, T | 1 |
| Inada, A; Nakanishi, T; Nishino, H; Sharma, OP; Tokuda, H | 1 |
| Heikkilä, P; Kahri, AI; Liu, J; Voutilainen, R | 1 |
| Bishop, WR; Fisher, GJ; McCombie, SW; Reynolds, NJ; Shankar, BB | 1 |
| Katiyar, SK; Mukhtar, H | 1 |
| Hanada, K; Hashimoto, I; Kida, K; Naganuma, A; Sawamura, D | 1 |
| Gilula, NB; Pozzi, A; Risek, B | 1 |
| Chou, FP; Chu, CY; Hsu, JD; Huang, CL; Lo, MH; Tseng, TH; Wang, CJ | 1 |
| Fürstenberger, G; Marks, F; Müller-Decker, K; Neufang, G; Scholz, K | 1 |
| Bolontrade, M; Conti, CJ; Jorcano, JL; Larcher, F; Murillas, R | 1 |
| Binder, RL; Conti, CJ; Gallagher, PM; Johnson, GR; Stockman, SL; Sundberg, JP | 1 |
| Baden, H; Calautti, E; Doetschman, T; Dotto, GP; Foitzik, K; Li, J | 1 |
| Agarwal, R; Katiyar, SK; Lahiri-Chatterjee, M; Mohan, RR | 1 |
| Berstein, LM; Diano, S; Eliza, M; Gutierrez, L; Harada, N; Lysiak, J; Mor, G; Naftolin, F; Santen, RJ; Wang, J; Yue, W | 1 |
| Deng, C; Fernandez-Salas, E; Hennings, H; Mirosh, E; Morgan, DL; Shalizi, A; Stanulis, E; Weinberg, WC; Yuspa, SH | 1 |
| Fischer, SM; La, E; Locniskar, MF; Muga, SJ | 1 |
| Kagoura, M; Matsui, C; Morohashi, M | 1 |
| Belury, MA; Kavanaugh, CJ; Liu, KL | 1 |
| Chen, YK; Lin, CC; Lin, LM | 1 |
| Liefer, KM; O'Malley, BW; Roop, DR; Tsai, S; Wang, XJ | 1 |
| Chang, RL; Conney, AH; Cui, XX; Gwynne, M; Huang, MT; Jerina, DM; Lou, YR; Lu, YP; Merkler, KA; Murthy, B; Wei, SJ; Xie, JG | 1 |
| Bowden, GT; Broome Powell, M; Gause, PR; Gregus, J; Hyman, P; Lluria-Prevatt, M; Nagle, R | 1 |
| Bergman, J; Möller, L; Rozell, BL; Skarin, T; Toftgård, R | 1 |
| Gau, E; Geisen, C; Haas, K; Karsunky, H; Möröy, T; Schmidt, T; Zevnik, B | 1 |
| Battalora, MS; Bishop, WR; Doll, RJ; Haseman, JK; Mahler, JF; Njoroge, FG; Tennant, RW; Trempus, CS | 1 |
| Fürstenberger, G; Krieg, P; Marks, F; Müller, K | 1 |
| Everett, C; Gavrilova, O; Gonzalez, FJ; Hudson, LD; Lee, SS; Li, W; Peters, JM; Reitman, ML; Ward, JM | 1 |
| Ding, M; Harki, D; Kayama, F; Kommineni, V; Luster, MI; Matheson, J; Simeonova, PP; Toriuma, W; Unimye, N; Vallyathan, V; Wang, S | 1 |
| Beltrán, L; Bol, D; Carbajal, S; Chan, K; DiGiovanni, J; Jorcano, J; Kiguchi, K; Moats, S | 1 |
| Kang, JK; Kim, DH; Kim, HS; Kim, JH; Lee, JE; Lee, SH; Seo, JS | 1 |
| Goerttler, K; Hesse, B; Löhrke, H | 1 |
| Pashko, LL; Schwartz, AG | 1 |
| Blasco, MA; Flores, JM; González-Suárez, E; Jorcano, JL; Martín-Caballero, J; Ramírez, A; Samper, E | 1 |
| Dreckschmidt, NE; Jansen, AP; Oberley, TD; Verma, AK; Verwiebe, EG; Wheeler, DL | 1 |
| Beltrán, L; Carbajal, S; DiGiovanni, J; Gimenez-Conti, I; Jiang, J; Kiguchi, K; Matsumoto, T; Rho, O | 1 |
| Boukamp, HK; Worst, PK | 1 |
| Scribner, JD; Süss, R | 1 |
| Nims, R; Viguera, C; Yuspa, SH | 1 |
| Goerttler, K; Komitowski, D; Löhrke, H | 1 |
| Scribner, JD; Slaga, TJ; Viaje, A | 1 |
| Goerttler, K; Loehrke, H | 1 |
| Boutwell, RK; Bowden, GT; Slaga, TJ | 1 |
| Gimenez-Conti, IB; Slaga, TJ | 1 |
| Beltran, L; Bhatt, TS; DiGiovanni, J; Walker, SE | 1 |
| Blumberg, PM; Krausz, KW; Szallasi, Z | 1 |
| Frenkel, K; Wei, H | 1 |
| Ito, K; Namikawa, S; Takeuchi, K | 1 |
| Beltrán, L; Chenicek, KJ; DiGiovanni, J; Imamoto, A; Naito, M; Skow, L; Walker, SE | 1 |
| Ferraro, T; Finnegan-Olive, T; Ho, CT; Huang, MT; Laskin, JD; Lou, YR; Mitchell, JM; Newmark, H; Wang, ZY; Yang, CS | 1 |
| Cameron, GS; Pence, BC | 1 |
| Akerström, G; Gylfe, E; Hellman, P; Larsson, R; Nygren, P; Rastad, J; Ridefelt, P | 1 |
| Dzau, VJ; Gibbons, GH; Pratt, RE | 1 |
| Meyer, SA; Moser, GJ; Smart, RC | 1 |
| Havens, M; Stanley, PL; Steiner, S; Tramposch, KM | 1 |
| Fürstenberger, G; Hanke, B; Marks, F; Thastrup, O | 1 |
| Fischer, SM; Slaga, TJ; Vo, TK | 1 |
| Blumberg, PM; Szallasi, Z | 1 |
| Belury, MA; Cumberland, AG; Fischer, SM; Locniskar, M; Patrick, KE | 1 |
| Beecroft, WA; Brandes, LJ; Hogg, GR | 1 |
| Belury, MA; Cumberland, AG; Fischer, SM; Leyton, J; Locniskar, M; Patrick, KE | 1 |
| Fine, LG; Herschman, HR; Kujubu, DA; Norman, JT | 1 |
| Hansen, LA; Monteiro-Riviere, NA; Smart, RC | 1 |
| Giacomoni, PU | 1 |
| Jani, H; Knowles, MA | 1 |
| Gallo, MA; Laskin, JD; Molloy, CJ | 1 |
| DiGiovanni, J; Kruszewski, FH; Naito, M; Naito, Y | 1 |
| Gill, TJ; Shinozuka, H; Yokota, K | 1 |
| Gupta, KP; Mehrotra, NK | 1 |
| Blumberg, PM; Hennings, H; Sharkey, NA; Yuspa, SH | 1 |
| Aizu, E; Hosoda, Y; Kato, R; Kiyoto, I; Nakadate, T; Yamamoto, S | 1 |
| Duell, EA; Elder, JT; Esmann, J; Fisher, GJ; Gupta, AK; Nickoloff, BJ; Talwar, HS; Voorhees, JJ | 1 |
| Fürstenberger, G; Marks, F; Schweizer, J | 1 |
| Bouquin, PL; Gendimenico, GJ; Nair, X; Tramposch, KM | 1 |
| Blumberg, PM; Szallasi, A | 1 |
| Baldwin, JK; Butler, AP; Cameron, GS; Fischer, SM; Jasheway, DW; Klann, RC; Patrick, KE | 1 |
| Aitken, A; Brooks, G; Evans, AT; Evans, FJ | 1 |
| Chida, K; Kuroki, T; Munakata, K; Murakami, Y | 1 |
| Czerniecki, B; Gad, SC; Reilly, C; Smith, AC; Witz, G | 1 |
| Graem, N | 1 |
| Anderson, LM; Rice, JM | 1 |
| Cohen, SM; Hasegawa, R; St John, M; Tibbels, TS | 1 |
| Crysup, SE; DiGiovanni, J; Ewing, MW; Phillips, JL; Slaga, TJ | 1 |
| Chouroulinkov, I; Giao, NB; Truhaut, R | 1 |
| Baker, RL; Erbland, JF; McKinney, RV; Schuster, GS; Singh, BB | 1 |
| Connor, MJ | 1 |
| Chenicek, KJ; DiGiovanni, J; Flynn, LM; Hirabayashi, N; Naito, M; Naito, Y | 1 |
| Conney, AH; Huang, MT; Mills, KJ; Monteiro-Riviere, NA; Smart, RC; Wong, CQ | 1 |
| Chida, K; Hirota, K; Kuroki, T; Yamada, S | 1 |
| Baldwin, JK; Cameron, GS; Fischer, SM; Jasheway, DW; Patrick, KE | 1 |
| Besemfelder, E; Fürstenberger, G; Krieg, P; Marks, F; Rincke, G; Rose-John, S | 1 |
| Blumberg, PM; Hennings, H; Herald, CL; Pettit, GR; Shores, R; Yuspa, SH | 1 |
| Bailly, J; Delescluse, C; Hensby, CN; Vaigot, P | 1 |
| Aldaz, CM; Clapp, N; Conti, CJ; Klein-Szanto, AJ; Nesnow, S; Slaga, TJ | 1 |
| Bhisey, RA; Sirsat, SM | 1 |
| Ebbesen, P | 1 |
| Hall, BK; Squier, CA | 1 |
| Aalfs, KK; Cantor, J; Coombs, MM; Decina, PC; DiGiovanni, J; Prichett, WP | 1 |
| Aldaz, CM; Conti, CJ; Gimenez, IB; Klein-Szanto, AJ; Slaga, TJ | 1 |
5 review(s) available for tetradecanoylphorbol acetate and Hyperplasia
| Article | Year |
|---|---|
Modification of epithelial cell differentiation in vivo by tumor-promoting diterpene esters.
Topics: Alkynes; Animals; Cell Differentiation; Cytoplasmic Granules; Epidermis; Hair; Hyperplasia; Keratins; Phorbol Esters; Phorbols; Protein Biosynthesis; Tetradecanoylphorbol Acetate; Time Factors; Tretinoin | 1982 |
The paradigm of two-stage carcinogenesis: a critical attitude.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Drug Interactions; Hyperplasia; Methylcholanthrene; Mice; Mice, Inbred C57BL; Mice, Nude; Models, Biological; Neoplasms; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Urethane | 1984 |
Tumor initiation and promotion.
Topics: Animals; Carcinogens; Cocarcinogenesis; DNA Repair; Dose-Response Relationship, Drug; Growth Inhibitors; Humans; Hyperplasia; Inflammation; Models, Biological; Mutation; Neoplasms; Phorbols; Tetradecanoylphorbol Acetate | 1978 |
The hamster cheek pouch model of carcinogenesis and chemoprevention.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzoyl Peroxide; Cheek; Cocarcinogenesis; Cricetinae; Hyperplasia; Keratins; Mesocricetus; Mouth Mucosa; Mouth Neoplasms; Precancerous Conditions; Tetradecanoylphorbol Acetate | 1992 |
Regeneration and the mechanism of epidermal tumor promotion.
Topics: Acetates; Acetic Acid; Animals; Carcinogens; Cell Differentiation; Connective Tissue Cells; Diterpenes; Epidermal Cells; Humans; Hyperplasia; Inflammation; Models, Biological; Regeneration; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate; Time Factors | 1985 |
227 other study(ies) available for tetradecanoylphorbol acetate and Hyperplasia
| Article | Year |
|---|---|
New strategy for antedrug application: development of metalloproteinase inhibitors as antipsoriatic drugs.
Topics: Amphiregulin; Animals; Cell Line; Disease Models, Animal; Drug Stability; EGF Family of Proteins; Epidermal Growth Factor; Glycoproteins; Growth Substances; Heparin-binding EGF-like Growth Factor; Humans; Hydroxylamines; Hyperplasia; Intercellular Signaling Peptides and Proteins; Isoquinolines; Magnetic Resonance Spectroscopy; Matrix Metalloproteinase Inhibitors; Metalloendopeptidases; Mice; Protease Inhibitors; Psoriasis; Recombinant Proteins; Skin; Tetradecanoylphorbol Acetate; Tetrahydroisoquinolines | 2002 |
P2RY6 Has a Critical Role in Mouse Skin Carcinogenesis by Regulating the YAP and β-Catenin Signaling Pathways.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; beta Catenin; Carcinogenesis; Hyperplasia; Keratinocytes; Mice; Receptors, Purinergic P2; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Wnt Signaling Pathway; YAP-Signaling Proteins | 2022 |
The transmembrane protein LRIG2 increases tumor progression in skin carcinogenesis.
Topics: Aged; Aged, 80 and over; Animals; Carcinogenesis; Cell Differentiation; Cell Line, Tumor; Disease Progression; Epidermis; ErbB Receptors; Homeostasis; Humans; Hyperplasia; Inflammation; Membrane Glycoproteins; Mice, Inbred C57BL; Phenotype; Protein Binding; Skin Neoplasms; Tetradecanoylphorbol Acetate; Thrombospondins | 2019 |
Targeted disruption of TC-PTP in the proliferative compartment augments STAT3 and AKT signaling and skin tumor development.
Topics: Alleles; Animals; Apoptosis; Cell Proliferation; Cell Transformation, Neoplastic; Disease Models, Animal; Epidermis; Gene Knockout Techniques; Gene Targeting; Hyperplasia; Keratinocytes; Mice; Mice, Knockout; Organ Specificity; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 2; Proto-Oncogene Proteins c-akt; Signal Transduction; Skin Neoplasms; STAT3 Transcription Factor; Tetradecanoylphorbol Acetate | 2017 |
Topical Application of Glycolipids from Isochrysis galbana Prevents Epidermal Hyperplasia in Mice.
Topics: Administration, Topical; Animals; Cell Survival; Cytokines; Drug Compounding; Female; Glycolipids; Haptophyta; Humans; Hyperplasia; Keratinocytes; Mice; Ointments; Skin; Skin Absorption; Skin Diseases; Tetradecanoylphorbol Acetate | 2017 |
Ingenol-3-Angelate Suppresses Growth of Melanoma Cells and Skin Tumor Development by Downregulation of NF-κB-Cox2 Signaling.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Apoptosis Regulatory Proteins; Carcinogenesis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclooxygenase 2; Diterpenes; Down-Regulation; Epidermis; Female; Hyperplasia; Inflammation; Melanoma; Mice, Inbred ICR; NF-kappa B; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2018 |
Xiao Tan He Wei Decoction reverses MNNG-induced precancerous lesions of gastric carcinoma in vivo and vitro: Regulation of apoptosis through NF-κB pathway.
Topics: Animals; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Disease Models, Animal; Drugs, Chinese Herbal; Epithelial-Mesenchymal Transition; Humans; Hyperplasia; Methylnitronitrosoguanidine; NF-kappa B; Precancerous Conditions; Rats, Wistar; Stomach Neoplasms; Tetradecanoylphorbol Acetate | 2018 |
Impaired wound repair in adult endoglin heterozygous mice associated with lower NO bioavailability.
Topics: Age Factors; Animals; Carcinogens; Cell Proliferation; Endoglin; Epidermis; Epithelial Cells; Female; Heterozygote; Hyperplasia; Intracellular Signaling Peptides and Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; Tetradecanoylphorbol Acetate; Wound Healing | 2014 |
The effects of dissociated glucocorticoids RU24858 and RU24782 on TPA-induced skin tumor promotion biomarkers in SENCAR mice.
Topics: Animals; Animals, Outbred Strains; Anticarcinogenic Agents; Biomarkers; Cell Proliferation; Cell Transformation, Neoplastic; Cyclooxygenase 2; Desoximetasone; Epidermis; Female; Gene Expression Regulation; Glucocorticoids; Hyperplasia; Interleukin-6; Mice; Nitric Oxide Synthase Type II; Proto-Oncogene Proteins c-jun; RNA, Messenger; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2014 |
A role for NF-κB activity in skin hyperplasia and the development of keratoacanthomata in mice.
Topics: Amino Acid Substitution; Animals; Cell Proliferation; Hyperplasia; Keratoacanthoma; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Papilloma; Receptors, Tumor Necrosis Factor, Type I; Signal Transduction; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factor RelA | 2013 |
Impact of mTORC1 inhibition on keratinocyte proliferation during skin tumor promotion in wild-type and BK5.AktWT mice.
Topics: Animals; Antibiotics, Antineoplastic; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Chromones; ErbB Receptors; Female; Flavonoids; Hair Follicle; Hyperplasia; Keratinocytes; Male; Mechanistic Target of Rapamycin Complex 1; Mice; Mice, Inbred ICR; Mice, Transgenic; Morpholines; Multiprotein Complexes; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Proto-Oncogene Proteins c-akt; Signal Transduction; Sirolimus; Skin Neoplasms; Tetradecanoylphorbol Acetate; TOR Serine-Threonine Kinases | 2014 |
Targeted deletion of RasGRP1 impairs skin tumorigenesis.
Topics: Animals; Cell Transformation, Neoplastic; Codon; Gene Deletion; Gene Targeting; Genes, ras; Guanine Nucleotide Exchange Factors; Hyperplasia; Mice; Mice, Knockout; Mutation; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcriptional Activation | 2014 |
Topical application of the adenosine A2A receptor agonist CGS-21680 prevents phorbol-induced epidermal hyperplasia and inflammation in mice.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Administration, Topical; Animals; Anti-Inflammatory Agents; Cell Proliferation; Collagen; Cytokines; Dexamethasone; Disease Models, Animal; Epidermis; Female; Hyperplasia; Inflammation; Mice; Peroxidase; Phenethylamines; Skin Diseases; Tetradecanoylphorbol Acetate | 2014 |
Targeted deletion and lipidomic analysis identify epithelial cell COX-2 as a major driver of chemically induced skin cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Differentiation; Cell Proliferation; Cyclooxygenase 2; Eicosanoids; Epidermis; Epithelial Cells; Gene Deletion; Gene Targeting; Hyperplasia; Keratinocytes; Lipid Metabolism; Macrophages; Mice; Myeloid Cells; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2014 |
Cancer-promoting effect of capsaicin on DMBA/TPA-induced skin tumorigenesis by modulating inflammation, Erk and p38 in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Capsaicin; Carcinogenesis; Cyclooxygenase 2; Female; Hyperplasia; Inflammation; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Mice; Mice, Inbred ICR; NF-kappa B; Nitric Oxide Synthase Type II; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Up-Regulation | 2015 |
Crosstalk between Desmoglein 2 and Patched 1 accelerates chemical-induced skin tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma in Situ; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cell Division; Cocarcinogenesis; Dermis; Desmoglein 2; Epidermis; Gene Knock-In Techniques; Genes, Reporter; Genetic Predisposition to Disease; Genotype; Hair Follicle; Hedgehog Proteins; Hyperplasia; Keratinocytes; Mice; Mice, Transgenic; Papilloma; Patched Receptors; Patched-1 Receptor; Receptors, Cell Surface; Signal Transduction; Skin Neoplasms; Stromal Cells; Tetradecanoylphorbol Acetate; Time Factors | 2015 |
Fractionation of a tumor-initiating UV dose introduces DNA damage-retaining cells in hairless mouse skin and renders subsequent TPA-promoted tumors non-regressing.
Topics: Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; DNA Damage; Epidermis; Female; Hyperplasia; Immunoenzyme Techniques; Male; Mice; Mice, Hairless; Mutation; Real-Time Polymerase Chain Reaction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53; Ultraviolet Rays | 2016 |
NO-dependent attenuation of TPA-induced immunoinflammatory skin changes in Balb/c mice by pindolol, heptaminol or ATRA, but not by verapamil.
Topics: Animals; Female; Fibrosis; Heptaminol; Hyperplasia; Killer Cells, Natural; Mice; Mice, Inbred BALB C; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pindolol; Skin; Tetradecanoylphorbol Acetate; Tretinoin; Verapamil | 2016 |
Elevated ΔNp63α Levels Facilitate Epidermal and Biliary Oncogenic Transformation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bile Duct Neoplasms; Cell Transformation, Neoplastic; Cells, Cultured; Cellular Senescence; Hyperplasia; Mice; Mice, Inbred C57BL; Mice, Transgenic; Phosphoproteins; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Trans-Activators | 2017 |
A novel DLX3-PKC integrated signaling network drives keratinocyte differentiation.
Topics: Animals; Antimicrobial Cationic Peptides; Calcium; Cell Adhesion; Cell Differentiation; Cell Proliferation; Cells, Cultured; Chemokines; Cytokines; Epidermis; Homeodomain Proteins; Humans; Hyperplasia; Indoles; Keratinocytes; Leukocytes; Maleimides; Mice; Mice, Transgenic; Protein Kinase C-alpha; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factors | 2017 |
Rictor/mTORC2 deficiency enhances keratinocyte stress tolerance via mitohormesis.
Topics: Acetylcysteine; Animals; Apoptosis; Cell Proliferation; Cells, Cultured; Cellular Senescence; Epirubicin; Glutamic Acid; Hyperplasia; Keratin-14; Keratinocytes; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria; Radiation Tolerance; Rapamycin-Insensitive Companion of mTOR Protein; Reactive Oxygen Species; Skin; Tetradecanoylphorbol Acetate; Transcriptome; X-Rays | 2017 |
Guggulsterone modulates MAPK and NF-kappaB pathways and inhibits skin tumorigenesis in SENCAR mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents, Phytogenic; Cyclooxygenase 2 Inhibitors; Edema; Female; Hyperplasia; I-kappa B Kinase; I-kappa B Proteins; MAP Kinase Signaling System; Mice; Mice, Inbred SENCAR; NF-kappa B; NF-KappaB Inhibitor alpha; Nitric Oxide Synthase Type II; Ornithine Decarboxylase Inhibitors; Phosphorylation; Pregnenediones; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2008 |
Perillyl alcohol attenuates Ras-ERK signaling to inhibit murine skin inflammation and tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Apoptosis; Disease Models, Animal; Drug Screening Assays, Antitumor; Edema; Extracellular Signal-Regulated MAP Kinases; Female; Hyperplasia; Inflammation; Mice; Monoterpenes; Oxidative Stress; ras Proteins; Signal Transduction; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 2009 |
Selective role for Mek1 but not Mek2 in the induction of epidermal neoplasia.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Differentiation; Cell Transformation, Neoplastic; Genotype; Hyperplasia; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Mice; Mice, Knockout; Mice, Transgenic; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Oncogene Protein v-akt; Papilloma; Phosphorylation; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2009 |
p38delta Mitogen-activated protein kinase is essential for skin tumor development in mice.
Topics: Animals; Animals, Newborn; Carcinoma; Cell Proliferation; Disease Progression; Epidermis; Female; Genes, ras; Genotype; Hyperplasia; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinase 13; Mutation; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2009 |
Impaired skin regeneration and remodeling after cutaneous injury and chemically induced hyperplasia in taps-transgenic mice.
Topics: Animals; Aspartic Acid Endopeptidases; Carcinogens; Cell Differentiation; Cell Division; Female; Filaggrin Proteins; Gene Expression; Humans; Hyperplasia; Keratinocytes; Lac Operon; Mice; Mice, Inbred C57BL; Mice, Transgenic; Phenotype; Promoter Regions, Genetic; Regeneration; Skin; Tetradecanoylphorbol Acetate; Ubiquitin C; Wound Healing | 2010 |
E6201, a novel kinase inhibitor of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase-1 and mitogen-activated protein kinase/extracellular signal-regulated kinase kinase kinase-1: in vivo effects on cutaneous inflammatory respon
Topics: Administration, Topical; Animals; Antineoplastic Agents, Phytogenic; Croton Oil; Dinitrofluorobenzene; Diterpenes; Drug Eruptions; Hyperplasia; Indicators and Reagents; Interleukin-17; Interleukin-23; Lactones; Male; MAP Kinase Kinase Kinase 1; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinase 1; Ornithine Decarboxylase; Peroxidase; Protein Kinase Inhibitors; Psoriasis; Skin; T-Lymphocytes; Tetradecanoylphorbol Acetate | 2010 |
Tumor necrosis factor-alpha-nuclear factor-kappa B-signaling enhances St2b2 expression during 12-O-tetradecanoylphorbol-13-acetate-induced epidermal hyperplasia.
Topics: Animals; Antibodies; Cholesterol Esters; Epidermis; Female; Hyperplasia; Inflammation; Mice; Mice, Inbred Strains; NF-kappa B; Nitriles; Protein Precursors; Receptors, Tumor Necrosis Factor; RNA, Small Interfering; Signal Transduction; Skin Neoplasms; Sulfones; Sulfotransferases; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2011 |
CYLD inhibits tumorigenesis and metastasis by blocking JNK/AP1 signaling at multiple levels.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Cysteine Endopeptidases; Deubiquitinating Enzyme CYLD; Disease Progression; Epidermal Cells; Epidermis; Humans; Hyperplasia; Immunoblotting; Immunoprecipitation; JNK Mitogen-Activated Protein Kinases; Lymphatic Metastasis; Mice; Mice, Transgenic; Mutation; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Tumor Cells, Cultured; Tumor Suppressor Proteins; Ubiquitination | 2011 |
Rapamycin is a potent inhibitor of skin tumor promotion by 12-O-tetradecanoylphorbol-13-acetate.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antibiotics, Antineoplastic; Anticarcinogenic Agents; Blotting, Western; Carcinogens; Humans; Hyperplasia; Mice; Neoplasm Staging; Papilloma; Proto-Oncogene Proteins c-akt; Signal Transduction; Sirolimus; Skin Neoplasms; Tetradecanoylphorbol Acetate; TOR Serine-Threonine Kinases; Tumor Cells, Cultured | 2011 |
The thyroid hormone receptors modulate the skin response to retinoids.
Topics: Alitretinoin; Animals; Blotting, Western; Cell Differentiation; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Epidermis; Female; Hyperplasia; Hypothyroidism; Interleukin-6; Keratins; Lymphocytes; Macrophages; Male; Mice; Mice, Knockout; Retinoids; Reverse Transcriptase Polymerase Chain Reaction; Skin; Tetradecanoylphorbol Acetate; Thyroid Hormone Receptors alpha; Thyroid Hormone Receptors beta; Tretinoin; Tumor Necrosis Factor-alpha | 2011 |
The possible separation of 12-O-tetradecanoylphorbol-13-acetate-induced skin inflammation and hyperplasia by compound A.
Topics: Acetates; Animals; Cyclooxygenase 2; Cytokines; Drug Eruptions; Epidermis; Female; Hyperplasia; Mice; Mice, Inbred SENCAR; NF-kappa B; Proto-Oncogene Proteins c-jun; Receptors, Glucocorticoid; RNA, Messenger; Skin; Tetradecanoylphorbol Acetate; Transcriptional Activation; Tyramine | 2013 |
Focal adhesion kinase is required for β-catenin-induced mobilization of epidermal stem cells.
Topics: Animals; beta Catenin; Focal Adhesion Protein-Tyrosine Kinases; Hair Follicle; Hematopoietic Stem Cell Mobilization; Hyperplasia; Mice; Skin Neoplasms; src-Family Kinases; Tetradecanoylphorbol Acetate | 2012 |
Baicalein inhibits DMBA/TPA-induced skin tumorigenesis in mice by modulating proliferation, apoptosis, and inflammation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Apoptosis; Cell Proliferation; Cell Transformation, Neoplastic; Female; Flavanones; Hyperplasia; Inflammation; Mice; Mice, Inbred C57BL; Plant Extracts; Scutellaria baicalensis; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2013 |
Blue light inhibits the growth of skin tumors in the v-Ha-ras transgenic mouse.
Topics: Animals; Epidermis; Female; Genes, ras; Hyperplasia; Keratins; Mice; Mice, Transgenic; Oncogene Protein p21(ras); Papilloma; Phototherapy; Precancerous Conditions; Recombinant Fusion Proteins; Skin Diseases; Skin Neoplasms; Tetradecanoylphorbol Acetate; Weight Gain | 2003 |
Disruption of protein kinase Ceta results in impairment of wound healing and enhancement of tumor formation in mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Female; Hyperplasia; Mice; Protein Kinase C; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Wound Healing | 2003 |
Structural analysis and tissue localization of human C4.4A: a protein homologue of the urokinase receptor.
Topics: Amino Acid Sequence; Animals; Breast Neoplasms; Cell Adhesion Molecules; Dermatologic Surgical Procedures; GPI-Linked Proteins; Humans; Hyperplasia; Immunohistochemistry; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Peptide Fragments; Peptide Mapping; Placenta; Protein Interaction Mapping; Protein Processing, Post-Translational; Receptors, Cell Surface; Receptors, Urokinase Plasminogen Activator; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Skin; Tetradecanoylphorbol Acetate; Wound Healing | 2004 |
Lupeol modulates NF-kappaB and PI3K/Akt pathways and inhibits skin cancer in CD-1 mice.
Topics: Administration, Topical; Animals; Anticarcinogenic Agents; Biomarkers, Tumor; Blotting, Western; Cyclooxygenase 2; Dose-Response Relationship, Drug; Edema; Enzyme Activation; Female; Hyperplasia; I-kappa B Kinase; Isoenzymes; Mice; Mice, Inbred Strains; Molecular Structure; NF-kappa B; Nitric Oxide Synthase; Ornithine Decarboxylase Inhibitors; Pentacyclic Triterpenes; Phorbol Esters; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Prostaglandin-Endoperoxide Synthases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Triterpenes | 2004 |
Experimental study to test the potential tumor promotion effect of a tooth bleaching agent.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carbamide Peroxide; Carcinogens; Cricetinae; Disease Models, Animal; Drug Combinations; Female; Hyperplasia; Male; Mesocricetus; Mice; Mice, Inbred SENCAR; Mouth Mucosa; Mouth Neoplasms; Oxidants; Peroxides; Precancerous Conditions; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tooth Bleaching; Urea | 2001 |
Early detection of alterations associated to oral cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Analysis of Variance; Animals; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cheek; Cricetinae; Hyperplasia; Mesocricetus; Mouth Neoplasms; Neoplasms, Radiation-Induced; Nucleolus Organizer Region; Silver Staining; Statistics, Nonparametric; Tetradecanoylphorbol Acetate | 2000 |
Anthocyanin- and hydrolyzable tannin-rich pomegranate fruit extract modulates MAPK and NF-kappaB pathways and inhibits skin tumorigenesis in CD-1 mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Anthocyanins; Carcinogens; Cyclooxygenase 2; Edema; Epidermis; Female; Fruit; Hydrolyzable Tannins; Hyperplasia; I-kappa B Kinase; Isoenzymes; Lythraceae; Mice; Mitogen-Activated Protein Kinases; NF-kappa B; Ornithine Decarboxylase; Phosphorylation; Plant Extracts; Prostaglandin-Endoperoxide Synthases; Protein Serine-Threonine Kinases; Signal Transduction; Skin Neoplasms; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tetradecanoylphorbol Acetate | 2005 |
Deficiency of protein kinase Calpha in mice results in impairment of epidermal hyperplasia and enhancement of tumor formation in two-stage skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cocarcinogenesis; Cytokines; DNA; Female; Hyperplasia; Keratinocytes; Mice; Protein Kinase C; Protein Kinase C-alpha; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2005 |
Monoclonal B-cell hyperplasia and leukocyte imbalance precede development of B-cell malignancies in uracil-DNA glycosylase deficient mice.
Topics: Animals; B-Lymphocytes; Concanavalin A; Cytokines; DNA; Flow Cytometry; Gene Expression Profiling; Genotype; Hyperplasia; Lectins; Leukocytes; Lipopolysaccharides; Lymphoma, B-Cell; Mice; Spleen; T-Lymphocytes; Tetradecanoylphorbol Acetate; Uracil-DNA Glycosidase | 2005 |
Mechanisms of SEPA 0009-induced tumorigenesis in v-rasHa transgenic Tg.AC mice.
Topics: Animals; Carcinogenicity Tests; Carcinogens; Cell Death; Cell Proliferation; Dermatitis, Irritant; Dioxolanes; Dose-Response Relationship, Drug; Epidermis; Female; Gene Expression; Genes, ras; Hyperplasia; Keratin-6; Keratinocytes; Keratins; Mice; Mice, Transgenic; Papilloma; Precancerous Conditions; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 2005 |
E2F1 suppresses skin carcinogenesis via the ARF-p53 pathway.
Topics: Animals; Carcinogens; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p21; E2F1 Transcription Factor; Genes, Tumor Suppressor; Hyperplasia; Mice; Mice, Transgenic; Promoter Regions, Genetic; Signal Transduction; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p14ARF; Tumor Suppressor Protein p53; Ultraviolet Rays | 2006 |
Lack of expression of the EP2 but not EP3 receptor for prostaglandin E2 results in suppression of skin tumor development.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogens; Cell Growth Processes; Cell Transformation, Neoplastic; Cyclic AMP; Dinoprostone; Drug Eruptions; Female; Hyperplasia; Keratinocytes; Mice; Mice, Knockout; Neovascularization, Pathologic; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP3 Subtype; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2005 |
Early epidermal destruction with subsequent epidermal hyperplasia is a unique feature of the papilloma-independent squamous cell carcinoma phenotype in PKCepsilon overexpressing transgenic mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cell Death; Cell Differentiation; Cell Proliferation; Chemotaxis, Leukocyte; Cocarcinogenesis; Disease Models, Animal; Epidermis; Female; Hair Follicle; Hyperplasia; Keratin-10; Keratinocytes; Keratins; Mice; Mice, Transgenic; Neutrophils; Phenotype; Precancerous Conditions; Protein Kinase C-epsilon; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 2005 |
Overexpression of the prostaglandin E2 receptor EP2 results in enhanced skin tumor development.
Topics: Animals; Animals, Newborn; Bromodeoxyuridine; Carcinoma, Squamous Cell; Cattle; Cell Culture Techniques; Cell Proliferation; Female; Humans; Hyperplasia; Inflammation; Keratinocytes; Keratins; Mice; Mice, Transgenic; Neovascularization, Pathologic; Polymerase Chain Reaction; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Skin Neoplasms; Tetradecanoylphorbol Acetate; Up-Regulation | 2006 |
Inhibition of the TPA-induced cutaneous inflammation and hyperplasia by EC-SOD.
Topics: Animals; Dermatitis, Contact; Hyperplasia; Interleukin-1; Mice; Mice, Transgenic; Oxidative Stress; Superoxide Dismutase; Tetradecanoylphorbol Acetate | 2006 |
Growth stimulation of UV-induced DNA damage retaining epidermal basal cells gives rise to clusters of p53 overexpressing cells.
Topics: Animals; Cell Proliferation; DNA Damage; Epidermis; Hyperplasia; Mice; Mice, Hairless; Pyrimidine Dimers; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53; Ultraviolet Rays | 2007 |
The PSORS1 locus gene CCHCR1 affects keratinocyte proliferation in transgenic mice.
Topics: Animals; Cell Movement; Cell Proliferation; Hyperplasia; Intracellular Signaling Peptides and Proteins; Keratinocytes; Mice; Mice, Transgenic; Psoriasis; Tetradecanoylphorbol Acetate; Wound Healing | 2008 |
Avarol inhibits TNF-alpha generation and NF-kappaB activation in human cells and in animal models.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Cell Line; Disease Models, Animal; Dose-Response Relationship, Drug; Epidermis; Female; Humans; Hyperplasia; Inflammation; Inflammation Mediators; Keratinocytes; Mice; Monocytes; NF-kappa B p50 Subunit; Peroxidase; Psoriasis; Sesquiterpenes; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2008 |
Chinese herbal medicine (Tuhuai extract) exhibits topical anti-proliferative and anti-inflammatory activity in murine disease models.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Cell Proliferation; Dermatitis, Allergic Contact; Dermatitis, Contact; Disease Models, Animal; Drugs, Chinese Herbal; Fabaceae; Female; Glycyrrhiza; Humans; Hyperplasia; Male; Mice; Mice, Hairless; Oxazolone; Phytotherapy; Psoriasis; Skin; Smilax; Tetradecanoylphorbol Acetate | 2008 |
Effect of an anticancer agent, vinblastine, on mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Cell Transformation, Viral; Female; Herpesvirus 4, Human; Hyperplasia; Mice; Skin; Tetradecanoylphorbol Acetate; Vinblastine; Virus Activation | 1984 |
Hairless mouse skin in two-stage chemical carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Division; Drug Resistance; Female; Hyperplasia; Male; Mice; Mice, Hairless; Neoplasm Regression, Spontaneous; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1982 |
Cell population kinetics in hairless mouse epidermis following a single topical application of 12-O-tetradecanoylphorbol-13-acetate II.
Topics: Animals; Cell Division; DNA; Epidermal Cells; Epidermis; Female; Hyperplasia; Interphase; Kinetics; Male; Mice; Mice, Nude; Mitosis; Phorbols; Tetradecanoylphorbol Acetate | 1983 |
Effects of the tumor promoter 12-O-tetradecanoyl-phorbol-13-acetate on newly synthesized proteins in mouse epidermis.
Topics: Animals; Diterpenes; Electrophoresis, Polyacrylamide Gel; Epidermis; Fluocinolone Acetonide; Hyperplasia; Keratins; Mice; Molecular Weight; Phorbol Esters; Phorbols; Protein Biosynthesis; Proteins; Terpenes; Tetradecanoylphorbol Acetate | 1981 |
Histological, proliferative, and biochemical alterations in dorsal epidermis of the Syrian golden hamster induced by 12-O-tetradecanoylphorbol-13-acetate and the calcium ionophore A 23187.
Topics: Adaptation, Physiological; Administration, Topical; Animals; Anti-Bacterial Agents; Calcimycin; Cell Division; Cricetinae; Drug Resistance; Hyperplasia; Keratins; Male; Mesocricetus; Phorbols; Skin; Tetradecanoylphorbol Acetate; Time Factors | 1982 |
Quantitative evaluation of dark keratinocytes induced by several promoting and hyperplasiogenic agents: their use as an early morphological indicator of tumor-promoting action.
Topics: Alkynes; Anthralin; Calcimycin; Carcinogens; Diterpenes; Epidermal Cells; Epidermis; Hyperplasia; Keratins; Phorbol Esters; Terpenes; Tetradecanoylphorbol Acetate | 1982 |
Patterns of epidermal cell proliferation.
Topics: Animals; Autoradiography; Cell Division; Cells, Cultured; Cytoplasmic Granules; Epidermal Cells; Epidermis; Epithelial Cells; Hyperplasia; Keratins; Melanocytes; Mice; Mice, Inbred C3H; Tetradecanoylphorbol Acetate | 1982 |
Protein modifications induced in mouse epidermis by potent and weak tumor-promoting hyperplasiogenic agents.
Topics: Amino Acids; Animals; Female; Hyperplasia; Keratins; Mice; Mice, Inbred Strains; Peptide Fragments; Phorbols; Proteins; Skin; Tetradecanoylphorbol Acetate | 1982 |
Effects of inhibitors of tumor promotion on 12-O-tetradecanoylphorbol-13-acetate-induced keratin modification in mouse epidermis.
Topics: Animals; Carcinogens; Cycloheximide; Electrophoresis, Polyacrylamide Gel; Epidermis; Female; Fluocinolone Acetonide; Hyperplasia; Keratins; Mice; Molecular Weight; Phorbols; Skin; Tetradecanoylphorbol Acetate; Tosylphenylalanyl Chloromethyl Ketone; Tretinoin | 1982 |
"Dark cells" in normal, hyperplastic, and promoter-treated mouse epidermis studied by conventional and high-voltage electron microscopy.
Topics: Aging; Animals; Epidermal Cells; Epidermis; Female; Hyperplasia; Mice; Microscopy, Electron; Neoplasms, Experimental; Phorbols; Pregnancy; Staining and Labeling; Tetradecanoylphorbol Acetate | 1983 |
Non-promoting hyperplasiogenic agents do not mimic the effects of phorbol, 12-myristate, 13-acetate on terminal differentiation of normal and transformed human keratinocytes.
Topics: Alkynes; Calcimycin; Carcinoma, Squamous Cell; Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Clone Cells; Humans; Hyperplasia; Keratins; Phorbols; Skin; Tetradecanoylphorbol Acetate | 1984 |
Specific binding, stimulation of rodent urinary bladder epithelial ornithine decarboxylase, and induction of transitional cell hyperplasia by the skin tumor promoter 12-O-tetradecanoylphorbol-13-acetate.
Topics: Animals; Caenorhabditis elegans Proteins; Carcinoma, Transitional Cell; Carrier Proteins; Female; Hyperplasia; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; Phorbol Esters; Phorbols; Protein Kinase C; Rats; Rats, Inbred F344; Receptors, Cell Surface; Receptors, Drug; Tetradecanoylphorbol Acetate; Urinary Bladder; Urinary Bladder Neoplasms | 1983 |
Nature of the epidermal hyperplasia produced by mezerein, a weak tumor promoter, in initiated skin of mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Diterpenes; Female; Hyperplasia; Mice; Neoplasms, Experimental; Phorbol Esters; Phorbols; Skin; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate | 1983 |
Effects of the skin mitogens tumor-promotor 12-O-tetradecanoylphorbol 13-acetate and divalent-cation-ionophore A23187 on ion fluxes and membrane potential in a murine epidermal cell line (HEL30) and in 3T3 fibroblasts.
Topics: Animals; Arachidonic Acids; Biological Transport; Calcimycin; Cations, Divalent; Cell Division; Cell Line; Epidermis; Fibroblasts; Hyperplasia; Membrane Potentials; Mice; Mitogens; Phorbols; Tetradecanoylphorbol Acetate | 1983 |
Effects of the anti-inflammatory agents indomethacin, metiamide and acetylsalicylic acid on the induction of hyperplasia in hamster cheek-pouch epithelium and ear epidermis.
Topics: Animals; Aspirin; Cricetinae; Ear, External; Epidermis; Hyperplasia; Indomethacin; Mesocricetus; Metiamide; Mouth Mucosa; Podophyllin; Tetradecanoylphorbol Acetate; Thiourea; Turpentine | 1984 |
Stages of tumour promotion in skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Aging; Animals; Animals, Newborn; Carcinogens; Cell Division; Cell Transformation, Neoplastic; Hyperplasia; Mice; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Wounds and Injuries | 1984 |
On the role of tumour promotion in chemical carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Dexamethasone; DNA Replication; Hyperplasia; Indomethacin; Mice; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin | 1984 |
Tumor promoters stimulate hyperplasia of microtubule organizing center and inhibit DNA synthesis in cultured cells.
Topics: DNA; Growth Inhibitors; HeLa Cells; Humans; Hyperplasia; Kinetics; Lyngbya Toxins; Melanoma; Microtubules; Mitotic Index; Organoids; Phorbols; Tetradecanoylphorbol Acetate | 1984 |
Keratinocyte damage produced by 12-O-tetradecanoylphorbol-13-acetate in rodent epidermis.
Topics: Animals; Epidermis; Female; Glucosephosphate Dehydrogenase; Histocytochemistry; Hyperplasia; Mice; Mice, Inbred Strains; NADPH Dehydrogenase; Phorbols; Tetradecanoylphorbol Acetate; Trypan Blue | 1984 |
The effect of promoters on 1,2-dimethylhydrazine-induced colon carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Colon; Colonic Neoplasms; Dimethylhydrazines; DNA; Female; Hyperplasia; Intestinal Mucosa; Male; Metaphase; Methylhydrazines; Mice; Mice, Inbred C57BL; Phorbols; Tetradecanoylphorbol Acetate; Time Factors; Vincristine | 1984 |
Can tumour promotion be effectively inhibited?
Topics: Animals; Antioxidants; Benzoyl Peroxide; Carcinogens; Humans; Hyperplasia; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1984 |
The nature of the epidermal growth produced by the first application of 12-0-tetradecanoyl-phorbol-13-acetate on the skin of mice initiated with dimethylbenzanthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Epidermis; Female; Hyperplasia; Mice; Mitosis; Organ Size; Phorbols; Proteins; Tetradecanoylphorbol Acetate | 1981 |
On the relationship between epidermal hyperproliferation and skin tumor promotion.
Topics: Calcimycin; Cell Division; Cocarcinogenesis; Dinoprost; Dinoprostone; Epidermal Cells; Hyperplasia; Indomethacin; Prostaglandins E; Prostaglandins F; Skin; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1982 |
Epidermal tumor promotion by regeneration.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Differentiation; Cell Division; Epidermis; Female; Hyperplasia; Mice; Neoplasms, Experimental; Regeneration; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1982 |
Correlation between sensitivity to tumor promotion and sustained epidermal hyperplasia of mice and rats treated with 12-O-tetra-decanoylphorbol-13-acetate.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Division; Dose-Response Relationship, Drug; Hyperplasia; Methylnitronitrosoguanidine; Mice; Mice, Inbred Strains; Phorbols; Rats; Rats, Inbred F344; Skin; Skin Neoplasms; Species Specificity; Tetradecanoylphorbol Acetate | 1982 |
Tumor promotion by phorbol esters in skin: evidence for a memory effect.
Topics: Animals; Carcinogens; Cell Line; Epidermis; Female; Hyperplasia; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Phorbol Esters; Phorbols; Precancerous Conditions; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1983 |
Epidermal cell cycle and transit times during hyperplastic growth induced by abrasion or treatment with 12-O-tetradecanoylphorbol-13-acetate.
Topics: Animals; Cell Cycle; Epidermal Cells; Epidermis; Female; Hyperplasia; Mice; Phorbols; Tetradecanoylphorbol Acetate; Thymidine | 1983 |
Tumor promoter-induced inhibition of epidermal growth factor binding to cultured mouse primary epidermal cells.
Topics: Animals; Calcium; Cells, Cultured; Epidermal Growth Factor; Hyperplasia; Mice; Peptides; Phorbol Esters; Phorbols; Skin; Temperature; Tetradecanoylphorbol Acetate | 1981 |
Effect of the active tumor promoter, 12-O-tetradecanoylphorbol-13-acetate on hair follicular growth and development of hair anlage tumors in the mouse skin: a comparison with human adnexal lesions.
Topics: Animals; Cocarcinogenesis; Epidermis; Female; Hair; Humans; Hyperplasia; Methylcholanthrene; Mice; Phorbols; Precancerous Conditions; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1982 |
Simple phorbol esters as inhibitors of tumor promotion by TPA in mouse skin.
Topics: Animals; Cocarcinogenesis; DNA; Dose-Response Relationship, Drug; Epidermis; Female; Hyperplasia; Mice; Neoplasms, Experimental; Phorbol Esters; Phorbols; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1982 |
Tumor promotion by regenerative epidermal hyperplasia in mouse skin.
Topics: Animals; Cell Transformation, Neoplastic; Hyperplasia; Mice; Regeneration; Skin; Skin Neoplasms; Skin Physiological Phenomena; Tetradecanoylphorbol Acetate | 1982 |
Must initiators come first? Tumorigenic and carcinogenic effects on skin of 3-methylcholanthrene and TPA in various sequences.
Topics: Animals; Carcinoma; Cell Division; DNA; Drug Synergism; Hyperplasia; Methylcholanthrene; Mice; Mice, Hairless; Papilloma; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1982 |
Hyperplasia and tumor promotion.
Topics: Animals; Croton Oil; Guinea Pigs; Humans; Hyperplasia; Mice; Ornithine Decarboxylase; Polyamines; Precancerous Conditions; Prostaglandins E; Psoriasis; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1982 |
Biological effects of phorbol ester tumor promoters in mouse skin.
Topics: Animals; Cell Division; Hyperplasia; Kinetics; Mice; Neoplasms, Experimental; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1982 |
Ribosomal RNA synthesis throughout epidermal hyperplastic growth induced by abrasion or treatment with 12-0-tetradecanoyl-phorbol-13-acetate.
Topics: Animals; Female; Hyperplasia; Mice; RNA, Ribosomal; Skin; Tetradecanoylphorbol Acetate | 1981 |
The time needed for normalization of hairless mouse epidermis after treatment with twice weekly topical skin applications of 10 nmol 12-O-tetradecanoylphorbol-13-acetate in acetone, or acetone alone, for 18 weeks. A morphologic and cell kinetic study.
Topics: Acetone; Animals; Cell Cycle; Female; Hyperplasia; Kinetics; Male; Mice; Mice, Inbred Strains; Phorbols; Skin; Skin Neoplasms; Skin Physiological Phenomena; Tetradecanoylphorbol Acetate; Time Factors | 1981 |
Epidermal growth following a single application of 12-O-tetradecanoyl-phorbol-13-acetate in mice.
Topics: Administration, Topical; Animals; DNA; Epidermal Cells; Epidermis; Female; Hyperplasia; Mice; Mitosis; Organ Size; Phorbols; Proteins; Regeneration; Tetradecanoylphorbol Acetate | 1980 |
An in vitro model of pancreas carcinogenesis: two-stage MNU--TPA effect.
Topics: Animals; Cell Transformation, Neoplastic; Hyperplasia; Methylnitrosourea; Mice; Mice, Nude; Models, Biological; Necrosis; Neoplasm Transplantation; Nitrosourea Compounds; Organ Culture Techniques; Pancreas; Pancreatic Neoplasms; Phorbols; Rats; Tetradecanoylphorbol Acetate; Transplantation, Heterologous | 1980 |
Effects of various promoters on the induction of hyperplastic nodules in rat liver.
Topics: 2-Acetylaminofluorene; Animals; Carbon Tetrachloride; Carcinogens; Diethylnitrosamine; Hyperplasia; Liver; Liver Neoplasms; Male; Organ Specificity; Rats; Saccharin; Tetradecanoylphorbol Acetate | 1980 |
Hyperplasia of Syrian hamster epidermis induced by single but not multiple treatments with 12-O-tetradecanoylphorbol-13-acetate.
Topics: Animals; Cricetinae; Dose-Response Relationship, Drug; Epidermal Cells; Epidermis; Hyperplasia; Male; Phorbols; Tetradecanoylphorbol Acetate | 1981 |
Changes in cytokeratins following treatment of hamster cheek pouch epithelia with hyperplastic or neoplastic agents.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alkynes; Animals; Cricetinae; Diterpenes; Epithelium; Gene Expression Regulation, Neoplastic; Hyperplasia; Immunoblotting; Immunohistochemistry; Keratins; Male; Molecular Weight; Mouth Mucosa; Mouth Neoplasms; Precancerous Conditions; Retinyl Esters; Tetradecanoylphorbol Acetate; Turpentine; Vitamin A | 1994 |
12-O-tetradecanoylphorbol-13-acetate promotion of transgenic mice expressing epidermal-targeted v-fos induces rasHA-activated papillomas and carcinomas without p53 mutation: association of v-fos expression with promotion and tumor autonomy.
Topics: Animals; Base Sequence; Biomarkers; Carcinoma; Cell Differentiation; Cell Transformation, Neoplastic; DNA, Neoplasm; Epidermis; Gene Expression Regulation, Neoplastic; Genes, fos; Genes, p53; Genes, ras; Hyperplasia; Keratins; Keratosis; Mice; Mice, Transgenic; Molecular Sequence Data; Mutation; Oncogene Proteins v-fos; Papilloma; ras Proteins; RNA, Neoplasm; Tetradecanoylphorbol Acetate | 1995 |
Elements controlling the expression and induction of the skin hyperproliferation-associated keratin K6.
Topics: Animals; Base Sequence; Cattle; Cell Division; Cells, Cultured; DNA; Enhancer Elements, Genetic; Gene Expression Regulation; Humans; Hyperplasia; Keratins; Molecular Sequence Data; Nuclear Proteins; Protein Binding; Sequence Homology, Nucleic Acid; Skin; Tetradecanoylphorbol Acetate; Tretinoin | 1995 |
Collagenase expression in transgenic mouse skin causes hyperkeratosis and acanthosis and increases susceptibility to tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acanthosis Nigricans; Animals; Carcinogenicity Tests; Collagenases; Disease Susceptibility; Epidermis; Haptoglobins; Humans; Hyperplasia; Keratosis; Mice; Mice, Transgenic; Papilloma; Promoter Regions, Genetic; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1995 |
Cholesterol sulfate, a second messenger for the eta isoform of protein kinase C, inhibits promotional phase in mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogens; Carcinoma, Squamous Cell; Cell Differentiation; Cell Division; Cholesterol Esters; Enzyme Activation; Enzyme Induction; Female; Hyperplasia; Isoenzymes; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; Protein Kinase C; Second Messenger Systems; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1995 |
The antiinflammatory activity of topically applied novel calcium-channel antagonists.
Topics: Administration, Cutaneous; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Calcium; Calcium Channel Blockers; Chemotaxis, Leukocyte; Clobetasol; Ear, External; Epidermis; Female; Humans; Hyperplasia; Inflammation; Mice; Neutrophils; Nifedipine; Peroxidase; Phosphatidylinositol Diacylglycerol-Lyase; Phosphodiesterase Inhibitors; Phospholipases A; Phosphoric Diester Hydrolases; Pituitary Neoplasms; Potassium Chloride; Pyrazoles; Terpenes; Tetradecanoylphorbol Acetate; Thyrotropin-Releasing Hormone; Tumor Cells, Cultured | 1995 |
Inhibition of 12-O-tetradecanoylphorbol-13-acetate and other skin tumor-promoter-caused induction of epidermal interleukin-1 alpha mRNA and protein expression in SENCAR mice by green tea polyphenols.
Topics: Animals; Anticarcinogenic Agents; Edema; Epidermis; Female; Hyperplasia; Interleukin-1; Mice; Mice, Inbred Strains; Phenols; Plant Extracts; RNA, Messenger; Skin Diseases; Skin Neoplasms; Tea; Tetradecanoylphorbol Acetate | 1995 |
Morphological changes of the nucleolar organizer regions induced by 7,12-dimethylbenz[a]anthracene in the hamster cheek pouch.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzoyl Peroxide; Cheek; Cricetinae; Hyperplasia; Male; Mesocricetus; Mouth Mucosa; Mouth Neoplasms; Nucleolus Organizer Region; Precancerous Conditions; Staining and Labeling; Tetradecanoylphorbol Acetate | 1993 |
Transforming growth factor beta 1 induction is associated with transforming growth factors beta 2 and beta 3 down-modulation in 12-O-tetradecanoylphorbol-13-acetate-induced skin hyperplasia.
Topics: Animals; Down-Regulation; Female; Hyperplasia; Mice; RNA; Skin; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta | 1993 |
Early overexpression of cyclin D1 protein in mouse skin carcinogenesis.
Topics: Animals; Carcinoma, Squamous Cell; Cyclin D1; Cyclins; Female; Formaldehyde; Gene Expression; Hyperplasia; Immunohistochemistry; Mice; Oncogene Proteins; Papilloma; Paraffin Embedding; Precancerous Conditions; Precipitin Tests; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tissue Fixation | 1995 |
Concerted action of TGF-beta 1 and its type II receptor in control of epidermal homeostasis in transgenic mice.
Topics: Activin Receptors, Type I; Animals; Base Sequence; Epidermal Cells; Epidermis; Female; Gene Targeting; Homeostasis; Hyperplasia; Keratinocytes; Male; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Transgenic; Mitotic Index; Molecular Sequence Data; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type I; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta | 1995 |
Patterns of tyrosine phosphorylation differ in vascular hypertrophy and hyperplasia.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Cells, Cultured; Hyperplasia; Hypertrophy; Muscle, Smooth, Vascular; Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Platelet-Derived Growth Factor; Prostaglandin Endoperoxides, Synthetic; Protein-Tyrosine Kinases; Rats; Tetradecanoylphorbol Acetate; Thromboxane A2; Type C Phospholipases; Tyrosine | 1994 |
Tumor-promoting activity of 2,4-dinitrofluorobenzene.
Topics: Animals; Carcinogens; Dermatitis, Contact; Dinitrofluorobenzene; Dose-Response Relationship, Drug; Enzyme Induction; Female; Gene Expression Regulation, Neoplastic; Genes, fos; Genes, jun; Hyperplasia; Mice; Mice, Inbred SENCAR; Ornithine Decarboxylase; Papilloma; Protein Kinase C; RNA, Small Nuclear; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1995 |
Inhibition of tumor promotion in benzo[a]pyrene-initiated CD-1 mouse skin by crocetin.
Topics: Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Carotenoids; Edema; Enzyme Induction; Female; Hydrogen Peroxide; Hyperplasia; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; Peroxidase; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Vitamin A | 1995 |
Lack of initiation and promotion potential of deoxynivalenol for skin tumorigenesis in Sencar mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Body Weight; Carcinoma, Squamous Cell; Data Interpretation, Statistical; Female; Hyperplasia; Mice; Organ Size; Papilloma; Random Allocation; Skin; Skin Neoplasms; Spleen; Tetradecanoylphorbol Acetate; Trichothecenes | 1995 |
Focal transgene expression associated with papilloma development in v-Ha-ras-transgenic TG.AC mice.
Topics: Animals; Cell Division; Epidermis; Gene Expression Regulation, Neoplastic; Genes, ras; Hyperplasia; Mice; Mice, Transgenic; Nuclear Proteins; Papilloma; Proliferating Cell Nuclear Antigen; Protein Kinase C; Proto-Oncogene Proteins p21(ras); Skin Neoplasms; Tetradecanoylphorbol Acetate | 1994 |
Interleukin-1 alpha mediates phorbol ester-induced inflammation and epidermal hyperplasia.
Topics: Analysis of Variance; Animals; Capillary Permeability; Cell Movement; Epidermis; Female; Hyperplasia; Immunohistochemistry; Inflammation; Interleukin-1; Mice; Mice, Inbred SENCAR; Recombinant Proteins; Tetradecanoylphorbol Acetate | 1994 |
Effect of curcumin on 12-O-tetradecanoylphorbol-13-acetate- and ultraviolet B light-induced expression of c-Jun and c-Fos in JB6 cells and in mouse epidermis.
Topics: Animals; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Cocarcinogenesis; Curcumin; Drug Interactions; Female; Gene Expression Regulation; Hyperplasia; Mice; Mice, Hairless; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 1994 |
Phorbol ester-induced leukotriene biosynthesis and tumor promotion in mouse epidermis.
Topics: Animals; Ear, External; Edema; Epidermis; Female; Hyperplasia; Indoles; Inflammation; Leukotriene B4; Mice; Skin Neoplasms; SRS-A; Tetradecanoylphorbol Acetate | 1994 |
Minimal role of enhanced cell proliferation in skin tumor promotion by mirex: a nonphorbol ester-type promoter.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Carcinogens; Cell Division; Cocarcinogenesis; Drug Synergism; Female; Hyperplasia; Mice; Mirex; Rats; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1993 |
Induction of interleukin-6 in the epidermis of mice in response to tumor-promoting agents.
Topics: Animals; Epidermis; Female; Hyperplasia; Interleukin-6; Mice; RNA, Messenger; Tetradecanoylphorbol Acetate | 1994 |
Inversion of carcinogen-promoter sequence: effects on mouse skin tumorigenesis and cellular growth kinetics.
Topics: Animals; Cell Division; Cell Transformation, Neoplastic; Disease Models, Animal; Female; Humans; Hyperplasia; Methylcholanthrene; Mice; Mice, Inbred Strains; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1993 |
Inhibition of skin tumorigenesis by rosemary and its constituents carnosol and ursolic acid.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Abietanes; Animals; Anticarcinogenic Agents; Antioxidants; Arachidonic Acid; Benzo(a)pyrene; Dermatitis, Contact; DNA; Drug Interactions; Enzyme Induction; Epidermis; Female; Hyperplasia; Magnoliopsida; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; Phenanthrenes; Plant Extracts; Skin; Skin Neoplasms; Spices; Tetradecanoylphorbol Acetate; Triterpenes; Tritium; Ursolic Acid | 1994 |
Intermittent 50 Hz magnetic field and skin tumor promotion in SENCAR mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cocarcinogenesis; Female; Hyperplasia; Magnetics; Mice; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1994 |
Sensitivity to tumor promotion of SENCAR and C57BL/6J mice correlates with oxidative events and DNA damage.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Carcinogens; Deoxyguanosine; DNA Damage; Hydrogen Peroxide; Hyperplasia; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Neutrophils; Peroxidase; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Thymidine | 1993 |
Protection against 12-O-tetradecanoylphorbol-13-acetate-caused inflammation in SENCAR mouse ear skin by polyphenolic fraction isolated from green tea.
Topics: Animals; Anticarcinogenic Agents; Dermatitis, Contact; Ear; Edema; Female; Flavonoids; Hyperplasia; Mice; Neutrophils; Phenols; Polymers; Polyphenols; Skin; Tea; Tetradecanoylphorbol Acetate | 1993 |
A study on skin tumour formation in mice with 50 Hz magnetic field exposure.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cocarcinogenesis; Electromagnetic Fields; Female; Hyperplasia; Mice; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1993 |
Comparison of 12-O-tetradecanoylphorbol-13-acetate and teleocidin for induction of epidermal hyperplasia, activation of epidermal PKC isozymes and skin tumor promotion in SENCAR and C57BL/6 mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cocarcinogenesis; Enzyme Activation; Female; Hyperplasia; Isoenzymes; Lyngbya Toxins; Mice; Mice, Inbred C57BL; Protein Kinase C; Skin; Tetradecanoylphorbol Acetate | 1993 |
Activation of the epidermal growth factor receptor by skin tumor promoters and in skin tumors from SENCAR mice.
Topics: Administration, Topical; Animals; Blotting, Western; Carcinogens; Catechols; Enzyme Inhibitors; Epidermal Cells; ErbB Receptors; Female; Hyperplasia; Isoenzymes; Keratinocytes; Mice; Mice, Inbred SENCAR; Nitriles; Phospholipase C gamma; Phosphorylation; Phosphotyrosine; Pyridines; Skin Neoplasms; Tetradecanoylphorbol Acetate; Type C Phospholipases; Tyrphostins | 1995 |
Thapsigargin, a weak skin tumor promoter, alters the growth and differentiation of mouse keratinocytes in culture.
Topics: Animals; Calcium; Carcinogens; Cell Differentiation; Cell Division; Cells, Cultured; Drug Synergism; Female; Hyperplasia; Keratinocytes; Mice; Phenotype; Skin; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1996 |
Paradoxical tumor inhibitory effect of p53 loss in transgenic mice expressing epidermal-targeted v-rasHa, v-fos, or human transforming growth factor alpha.
Topics: Animals; Animals, Newborn; Cell Differentiation; Cell Division; Cell Transformation, Neoplastic; Cocarcinogenesis; Crosses, Genetic; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Epidermis; Genes, fos; Genes, p53; Genes, ras; Hyperplasia; Keratinocytes; Mice; Mice, Knockout; Mice, Transgenic; Oncogene Protein p21(ras); Oncogene Proteins v-fos; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha; Transgenes | 1996 |
Sodium ionophore converts growth manner of vascular smooth muscle cells from spontaneously hypertensive rats.
Topics: Animals; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Dose-Response Relationship, Drug; Gramicidin; Hyperplasia; Hypertension; Hypertrophy; Ionophores; Male; Muscle Development; Muscle, Smooth, Vascular; Phosphorylation; Protein Kinase C; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium; Tetradecanoylphorbol Acetate; Time Factors | 1996 |
Susceptibility of 129/SvEv mice in two-stage carcinogenesis protocols to 12-O-tetradecanoylphorbol-13-acetate promotion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Cutaneous; Animals; Biomarkers; Carcinogens; Carcinoma, Squamous Cell; Cocarcinogenesis; Dermatitis, Contact; Disease Susceptibility; Dose-Response Relationship, Drug; Drug Synergism; Epidermis; Hyperplasia; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Mutant Strains; Neutrophils; Papilloma; Peroxidase; Skin Neoplasms; Species Specificity; Tetradecanoylphorbol Acetate | 1997 |
Altered glucocorticoid receptor expression and function during mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Female; Fluocinolone Acetonide; Hyperplasia; Keratinocytes; Mice; Mice, Inbred Strains; Papilloma; Receptors, Glucocorticoid; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factors | 1997 |
Analysis of the ability of 12-O-tetradecanoylphorbol-13-acetate to induce epidermal hyperplasia, transforming growth factor-alpha, and skin tumor promotion in wa-1 mice.
Topics: Amphiregulin; Animals; Antineoplastic Agents; Carcinogens; EGF Family of Proteins; Epidermal Growth Factor; Female; Glycoproteins; Growth Substances; Heparin; Heparin-binding EGF-like Growth Factor; Hyperplasia; Intercellular Signaling Peptides and Proteins; Male; Mice; Mice, Inbred C57BL; Mice, Inbred SENCAR; Mice, Mutant Strains; Neutrophils; RNA, Messenger; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha | 1997 |
Overexpression of insulin-like growth factor-1 induces hyperplasia, dermal abnormalities, and spontaneous tumor formation in transgenic mice.
Topics: Animals; Carcinogens; Epidermis; Fluorescent Antibody Technique, Indirect; Humans; Hyperplasia; Insulin-Like Growth Factor I; Keratins; Mice; Mice, Transgenic; Neoplasms, Experimental; Skin Abnormalities; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1997 |
Anti-tumor promoting activities of lantadenes on mouse skin tumors and mouse hepatic tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogens; Diethylnitrosamine; Female; Hyperplasia; Liver Neoplasms; Mice; Mice, Inbred ICR; Oleanolic Acid; Papilloma; Phenobarbital; Plants, Medicinal; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1997 |
Ribonucleic acid expression of the CLA-1 gene, a human homolog to mouse high density lipoprotein receptor SR-BI, in human adrenal tumors and cultured adrenal cells.
Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocorticotropic Hormone; Animals; Blotting, Northern; Bucladesine; CD36 Antigens; Cells, Cultured; Cushing Syndrome; Gene Expression; Humans; Hyperplasia; Membrane Proteins; Mice; Molecular Sequence Data; Receptors, Immunologic; Receptors, Lipoprotein; Receptors, Scavenger; RNA, Messenger; Scavenger Receptors, Class B; Staurosporine; Tetradecanoylphorbol Acetate | 1997 |
SCH 47112, a novel staurosporine derivative, inhibits 12-O-tetradecanoylphorbol-13-acetate-induced inflammation and epidermal hyperplasia in hairless mouse skin.
Topics: Animals; Anti-Inflammatory Agents; Cells, Cultured; Enzyme Inhibitors; Epidermis; Humans; Hyperplasia; Keratinocytes; Male; Mice; Mice, Hairless; Molecular Structure; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate | 1997 |
Inhibition of phorbol ester tumor promoter 12-O-tetradecanoylphorbol-13-acetate-caused inflammatory responses in SENCAR mouse skin by black tea polyphenols.
Topics: Animals; Carcinogens; Cell Movement; Edema; Enzyme Induction; Epidermis; Female; Flavonoids; Hyperplasia; Interleukin-1; Leukocytes; Mice; Ornithine Decarboxylase; Phenols; Polymers; Polyphenols; Prostaglandin-Endoperoxide Synthases; RNA, Messenger; Skin; Skin Diseases; Tea; Tetradecanoylphorbol Acetate | 1997 |
Epidermal proliferation of the skin in metallothionein-null mice.
Topics: Animals; Cholera Toxin; Copper; Epidermis; Hyperplasia; Male; Metallothionein; Mice; Mice, Inbred C57BL; Mice, Knockout; Skin; Tetradecanoylphorbol Acetate; Ultraviolet Rays; Zinc | 1998 |
Modulation of gap junction expression during transient hyperplasia of rat epidermis.
Topics: Animals; Antineoplastic Agents; Carcinogens; Cell Differentiation; Connexin 26; Connexin 43; Connexins; Epidermis; Gap Junctions; Gene Expression; Hyperplasia; Keratinocytes; Keratins; Rats; Rats, Wistar; RNA, Messenger; Tetradecanoylphorbol Acetate; Tretinoin | 1998 |
Inhibitory effect of Hibiscus protocatechuic acid on tumor promotion in mouse skin.
Topics: Animals; Anticarcinogenic Agents; Carcinogens; Edema; Female; Hydrogen Peroxide; Hydroxybenzoates; Hyperplasia; Malvaceae; Mice; Ornithine Decarboxylase; Peroxidase; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1998 |
Localization of prostaglandin-H synthase-1 and -2 in mouse skin: implications for cutaneous function.
Topics: Animals; Calcium; Cells, Cultured; Cyclooxygenase 1; Epidermis; Female; Hyperplasia; Isoenzymes; Keratinocytes; Membrane Proteins; Mice; Prostaglandin-Endoperoxide Synthases; Skin; Tetradecanoylphorbol Acetate | 1998 |
VEGF/VPF overexpression in skin of transgenic mice induces angiogenesis, vascular hyperpermeability and accelerated tumor development.
Topics: Animals; Capillary Permeability; Endothelial Growth Factors; Genes, ras; Hyperplasia; Keratins; Lymphokines; Mice; Mice, Transgenic; Neovascularization, Pathologic; Neovascularization, Physiologic; Papilloma; Precancerous Conditions; Receptor Protein-Tyrosine Kinases; Receptors, Growth Factor; Receptors, Vascular Endothelial Growth Factor; Regulatory Sequences, Nucleic Acid; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1998 |
Squamous cell hyperplastic foci: precursors of cutaneous papillomas induced in SENCAR mice by a two-stage carcinogenesis regimen.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Epidermis; Female; Hyperplasia; Mice; Mice, Inbred SENCAR; Neoplasm Regression, Spontaneous; Neoplasm Staging; Papilloma; Precancerous Conditions; Sebaceous Glands; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1998 |
TGF-beta3, but not TGF-beta1, protects keratinocytes against 12-O-tetradecanoylphorbol-13-acetate-induced cell death in vitro and in vivo.
Topics: Actins; Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cell Death; Cells, Cultured; Hyperplasia; JNK Mitogen-Activated Protein Kinases; Keratinocytes; Mice; Mice, Knockout; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Rabbits; Skin; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta | 1999 |
A flavonoid antioxidant, silymarin, affords exceptionally high protection against tumor promotion in the SENCAR mouse skin tumorigenesis model.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Carcinogens; Cell Division; DNA; Edema; Female; Hyperplasia; Lipid Peroxidation; Mice; Mice, Inbred SENCAR; Silymarin; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1999 |
Macrophages, estrogen and the microenvironment of breast cancer.
Topics: Antineoplastic Agents; Aromatase; Breast; Breast Neoplasms; Carcinoma in Situ; Cell Division; Cell Line; Enzyme Inhibitors; Estradiol; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Hyperplasia; Immunohistochemistry; Letrozole; Macrophages; Monocytes; Nitriles; Placenta; Pregnancy; Testosterone; Tetradecanoylphorbol Acetate; Transcription, Genetic; Triazoles | 1998 |
Genetic deletion of p21WAF1 enhances papilloma formation but not malignant conversion in experimental mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Differentiation; Biomarkers; Carcinogens; Carcinoma, Squamous Cell; Cell Division; Cocarcinogenesis; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Disease Progression; Epidermis; Gene Deletion; Genes, p53; Genotype; Hyperplasia; Mice; Mice, Knockout; Mitotic Index; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53 | 1999 |
Altered expression of interleukin-1 receptor antagonist in different stages of mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anthralin; Blotting, Northern; Blotting, Western; Carcinogens; Carcinoma, Squamous Cell; Cell Polarity; Cytoplasm; Disease Progression; Epidermis; Gene Expression Regulation, Neoplastic; Hyperplasia; Inflammation; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Keratinocytes; Mice; Mice, Inbred SENCAR; Neoplasm Proteins; Papilloma; Precancerous Conditions; RNA, Messenger; RNA, Neoplasm; Sialoglycoproteins; Skin Diseases; Skin Neoplasms; Tetradecanoylphorbol Acetate; Thapsigargin; Tumor Cells, Cultured | 1999 |
Phytol is a novel tumor promoter on ICR mouse skin.
Topics: Animals; Carcinogens; Female; Hyperplasia; Mice; Mice, Inbred ICR; Ornithine Decarboxylase; Phytol; Radioligand Assay; Tetradecanoylphorbol Acetate; Toxicity Tests | 1999 |
Effect of dietary conjugated linoleic acid on phorbol ester-induced PGE2 production and hyperplasia in mouse epidermis.
Topics: Analysis of Variance; Animals; Anticarcinogenic Agents; Capillary Permeability; Dietary Fats; Dinoprostone; DNA Primers; Dose-Response Relationship, Drug; Epidermis; Female; Genes, myc; Hyperplasia; Linoleic Acid; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; Random Allocation; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1999 |
Placental glutathione S-transferase isoenzyme expression during promotion of two-stage hamster cheek-pouch carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cheek; Cricetinae; Glutathione Transferase; Hyperplasia; Immunohistochemistry; Isoenzymes; Male; Mouth Mucosa; Neoplastic Processes; Oropharyngeal Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1999 |
Development of gene-switch transgenic mice that inducibly express transforming growth factor beta1 in the epidermis.
Topics: Animals; Bromodeoxyuridine; DNA-Binding Proteins; Epidermis; Estrenes; Fungal Proteins; Gene Expression Regulation, Developmental; Hyperplasia; Membrane Proteins; Mice; Mice, Transgenic; Neovascularization, Physiologic; Promoter Regions, Genetic; Receptors, Progesterone; RNA, Messenger; Saccharomyces cerevisiae Proteins; Tetradecanoylphorbol Acetate; Transcription Factors; Transcriptional Activation; Transforming Growth Factor beta; Wound Healing | 1999 |
Dose-dependent mutation profile in the c-Ha-ras proto-oncogene of skin tumors in mice initiated with benzo[a]pyrene.
Topics: Administration, Cutaneous; Amino Acid Substitution; Animals; Benzo(a)pyrene; Carcinogens; Carcinoma in Situ; Cocarcinogenesis; Codon; DNA; DNA Mutational Analysis; DNA, Neoplasm; Dose-Response Relationship, Drug; Epidermis; Exons; Female; Genes, ras; Hyperplasia; Keratoacanthoma; Mice; Papilloma; Point Mutation; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Proto-Oncogene Proteins p21(ras); Skin Neoplasms; Tetradecanoylphorbol Acetate | 1999 |
Induction of melanoma in TPras transgenic mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Albinism; Animals; Carcinoma; Gene Expression Regulation; Genes, ras; Genetic Predisposition to Disease; Hair Color; Hyperplasia; Melanocytes; Melanoma; Mice; Mice, SCID; Mice, Transgenic; Monophenol Monooxygenase; Neoplasm Metastasis; Neoplasms, Radiation-Induced; Papilloma; Promoter Regions, Genetic; Skin Neoplasms; Skin Pigmentation; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 1999 |
Protection against 12-O-tetradecanoylphorbol-13-acetate induced skin-hyperplasia and tumor promotion, in a two-stage carcinogenesis mouse model, by the 2,3-dimethyl-6(2-dimethylaminoethyl)-6H-indolo-[2,3-b]quinoxaline analogue of ellipticine.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Benzoyl Peroxide; Carcinogens; Dermatitis, Contact; Female; Hyperplasia; Indoles; Mice; Mice, Inbred SENCAR; Precancerous Conditions; Quinoxalines; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1999 |
Oncogenic potential of cyclin E in T-cell lymphomagenesis in transgenic mice: evidence for cooperation between cyclin E and Ras but not Myc.
Topics: Animals; Cell Transformation, Neoplastic; Cyclin E; Embryo, Mammalian; Fibroblasts; Genes, myc; Genes, ras; Hyperplasia; Ionomycin; Locus Control Region; Lymphoid Tissue; Lymphoma, T-Cell; Methylnitrosourea; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Transgenic; Point Mutation; Protamine Kinase; Rats; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymus Gland | 1999 |
A farnesyl transferase inhibitor suppresses TPA-mediated skin tumor development without altering hyperplasia in the ras transgenic Tg.AC mouse.
Topics: Alkyl and Aryl Transferases; Animals; Benzazepines; Crosses, Genetic; Enzyme Inhibitors; Farnesyltranstransferase; Female; Genes, ras; Globins; Homozygote; Hyperplasia; Keratinocytes; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Transgenic; Papilloma; Promoter Regions, Genetic; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 2000 |
Expression of PGF(2alpha) receptor mRNA in normal, hyperplastic and neoplastic skin.
Topics: Adolescent; Animals; Base Sequence; Carcinogens; Dinoprost; DNA Primers; Female; Humans; Hyperplasia; Mice; Polymerase Chain Reaction; Receptors, Prostaglandin; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2000 |
Growth, adipose, brain, and skin alterations resulting from targeted disruption of the mouse peroxisome proliferator-activated receptor beta(delta).
Topics: Adipose Tissue; Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Constitution; Body Temperature; Brain; CD36 Antigens; Embryonic and Fetal Development; Fasting; Female; Hyperplasia; Inflammation; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Myelin Sheath; Receptors, Cytoplasmic and Nuclear; Skin; Sulindac; Tetradecanoylphorbol Acetate; Transcription Factors | 2000 |
Arsenic mediates cell proliferation and gene expression in the bladder epithelium: association with activating protein-1 transactivation.
Topics: Animals; Arsenates; Arsenites; CCAAT-Enhancer-Binding Proteins; Cell Division; Crosses, Genetic; DNA Damage; DNA-Binding Proteins; Early Growth Response Protein 1; Female; GADD45 Proteins; Gene Expression Regulation; Genes, fos; Genes, jun; Humans; Hyperplasia; Immediate-Early Proteins; Intracellular Signaling Peptides and Proteins; Luciferases; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Transgenic; Proteins; Sodium Compounds; Tetradecanoylphorbol Acetate; Tissue Distribution; Transcription Factor AP-1; Transcription Factor CHOP; Transcription Factors; Transcriptional Activation; Urinary Bladder; Urothelium | 2000 |
Constitutive expression of erbB2 in epidermis of transgenic mice results in epidermal hyperproliferation and spontaneous skin tumor development.
Topics: Animals; Carcinogens; Carcinoma, Squamous Cell; Cattle; Cell Differentiation; Cell Division; Cell Transformation, Neoplastic; Cocarcinogenesis; Dimerization; Disease Progression; Epidermis; ErbB Receptors; Female; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Genes, erbB-2; Genes, ras; Genes, Synthetic; Hyperplasia; Keratins; Male; Mice; Mice, Inbred ICR; Mice, Transgenic; Neoplasm Proteins; Papilloma; Phosphorylation; Promoter Regions, Genetic; Protein Processing, Post-Translational; Rats; Receptor, ErbB-2; Receptor, ErbB-3; Recombinant Fusion Proteins; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transgenes | 2000 |
Development of spontaneous hyperplastic skin lesions and chemically induced skin papillomas in transgenic mice expressing human papillomavirus type 16 E6/E7 genes.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cocarcinogenesis; Female; Gene Expression; Humans; Hyperplasia; Mice; Mice, Inbred ICR; Mice, Transgenic; Monophenol Monooxygenase; Oncogene Proteins, Viral; Papilloma; Papillomaviridae; Papillomavirus E7 Proteins; Pregnancy; Repressor Proteins; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2000 |
Two-stage carcinogenesis in NMRI mice: intravaginal application of 7,12-dimethylbenz[a]anthracene as initiator followed by the phorbol ester 12-O-tetradecanoylphorbol-13-acetate as promoter.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenoma; Administration, Intravaginal; Animals; Carcinogens; Carcinoma; Cocarcinogenesis; Drug Synergism; Female; Hyperplasia; Leukemia, Experimental; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Models, Animal; Neoplasms, Experimental; Organ Specificity; Ovarian Neoplasms; Papilloma; Precancerous Conditions; Sarcoma, Experimental; Specific Pathogen-Free Organisms; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Vagina; Vaginal Neoplasms | 1980 |
Suppression of 12-O-tetradecanoylphorbol-13-acetate-induced epidermal hyperplasia and inflammation by the dehydroepiandrosterone analog 16alpha-fluoro-5-androsten-17-one and its reversal by NADPH liposomes.
Topics: Androstenes; Animals; Antineoplastic Agents; Binding, Competitive; Capillary Permeability; Carcinogens; Cations; Corticosterone; Dehydroepiandrosterone; DNA; Epidermis; Female; Free Radicals; Hyperplasia; Inflammation; Liposomes; Mice; NADP; Tetradecanoylphorbol Acetate | 2001 |
Increased epidermal tumors and increased skin wound healing in transgenic mice overexpressing the catalytic subunit of telomerase, mTERT, in basal keratinocytes.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Catalytic Domain; Cattle; DNA-Binding Proteins; Female; Gastric Mucosa; Genes, p53; Genetic Therapy; Hyperplasia; Keratinocytes; Keratins; Mice; Mice, Knockout; Mice, Transgenic; Mouth Mucosa; Neoplasms, Experimental; Papilloma; Protein Subunits; RNA; Skin; Skin Neoplasms; Stomach; Telomerase; Telomere; Tetradecanoylphorbol Acetate; Vagina; Wound Healing | 2001 |
Relation of the induction of epidermal ornithine decarboxylase and hyperplasia to the different skin tumor-promotion susceptibilities of protein kinase C alpha, -delta and -epsilon transgenic mice.
Topics: Animals; Carcinogens; Disease Models, Animal; Enzyme Induction; Humans; Hyperplasia; Immunohistochemistry; Isoenzymes; Keratinocytes; Mice; Mice, Transgenic; Microscopy, Electron; Ornithine Decarboxylase; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-delta; Protein Kinase C-epsilon; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2001 |
Overexpression of a constitutively active form of c-src in skin epidermis increases sensitivity to tumor promotion by 12-O-tetradecanoylphorbol-13-acetate.
Topics: Animals; Carcinogens; Epidermis; Hyperplasia; Keratins; Kinetics; Mice; Mice, Transgenic; Mutation; Promoter Regions, Genetic; Proto-Oncogene Proteins pp60(c-src); Skin Neoplasms; Tetradecanoylphorbol Acetate | 2002 |
[Skin transplantation in the study of chemical carcinogenesis. III. Reduced papilloma-formation after initiation during epidermal hyperplasia induced by skin grafting or by a single application of the cocarcinogen TPA].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Hyperplasia; Mice; Mice, Inbred C3H; Papilloma; Skin; Skin Transplantation; Tetradecanoylphorbol Acetate; Time Factors; Transplantation, Autologous | 1975 |
Maintenance of human skin on nude mice for studies of chemical carcinogenesis.
Topics: Animals; Carcinogens; Female; Humans; Hyperplasia; Male; Mice; Mice, Nude; Models, Biological; Neoplasms, Experimental; Skin; Skin Neoplasms; Skin Transplantation; Species Specificity; Tetradecanoylphorbol Acetate; Transplantation, Heterologous; Urethane | 1979 |
Epidermal intercellular relationships during carcinogenesis and cocarcinogenesis as revealed by scanning electron microscopy.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Autoradiography; Cell Transformation, Neoplastic; Cocarcinogenesis; Epithelium; Extracellular Space; Female; Hyperplasia; Intercellular Junctions; Mice; Microscopy, Electron, Scanning; Skin; Tetradecanoylphorbol Acetate | 1977 |
Epidermal cell proliferation and promoting ability of phorbol esters.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Division; Dose-Response Relationship, Drug; Drug Synergism; Edema; Female; Hyperplasia; Inflammation; Mice; Neoplasms, Experimental; Papilloma; Phorbol Esters; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1976 |
Improved tumour yields by means of a TPA-DMBA-TPA variation of the Berenrlum-Mottram experiment on the back skin of NMRI mice. The effect of stationary hyperplasia without inflammation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Carcinoma; Female; Hyperplasia; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Papilloma; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1976 |
Acetic acid, a potent stimulator of mouse epidermal macromolecular synthesis and hyperplasia but with weak tumor-promoting ability.
Topics: Acetates; Animals; Croton Oil; Cytidine; DNA; Dose-Response Relationship, Drug; Female; Hyperplasia; Leucine; Mice; Neoplasms, Experimental; Papilloma; Proteins; RNA; Skin; Skin Neoplasms; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Thymidine | 1975 |
Induction of epidermal ornithine decarboxylase activity in mouse skin exposed to biogenic silica fibers.
Topics: Animals; Enzyme Induction; Female; Hyperplasia; Mice; Ornithine Decarboxylase; Silicon Dioxide; Skin; Tetradecanoylphorbol Acetate | 1992 |
Non-promoting 12-deoxyphorbol 13-esters as potent inhibitors of phorbol 12-myristate 13-acetate-induced acute and chronic biological responses in CD-1 mouse skin.
Topics: Animals; Dermatitis, Contact; Drug Antagonism; Enzyme Induction; Hyperplasia; Keratins; Mice; Ornithine Decarboxylase; Peroxidase; Phorbol Esters; Skin; Tetradecanoylphorbol Acetate | 1992 |
Suppression of tumor promoter-induced oxidative events and DNA damage in vivo by sarcophytol A: a possible mechanism of antipromotion.
Topics: Animals; Antineoplastic Agents; Cell Movement; Diterpenes; DNA; DNA Damage; Female; Hydrogen Peroxide; Hyperplasia; Mice; Neutrophils; Oxidation-Reduction; Skin; Tetradecanoylphorbol Acetate | 1992 |
[Effect of the dry distillation tar of delipidated soybean (Glyteer) on a psoriasic model in the mouse (4)].
Topics: Animals; Dermatologic Agents; Disease Models, Animal; Edema; Glycine max; Hyperplasia; Male; Mice; Proteins; Psoriasis; Skin; Tars; Tetradecanoylphorbol Acetate | 1992 |
Further genetic analyses of skin tumor promoter susceptibility using inbred and recombinant inbred mice.
Topics: Animals; Chromosome Mapping; Crosses, Genetic; Dermatitis; Dose-Response Relationship, Drug; Epidermis; Hyperplasia; Mice; Mice, Inbred Strains; Skin Neoplasms; Species Specificity; Tetradecanoylphorbol Acetate | 1992 |
Inhibitory effect of topical application of a green tea polyphenol fraction on tumor initiation and promotion in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Benzo(a)pyrene; Edema; Enzyme Induction; Female; Flow Cytometry; Hydrogen Peroxide; Hyperplasia; Mice; Ornithine Decarboxylase; Phenols; Skin; Skin Neoplasms; Tea; Tetradecanoylphorbol Acetate | 1992 |
Effects of multiple applications of tumor promoters and ultraviolet radiation on epidermal proliferation and antioxidant status.
Topics: Alkynes; Animals; Antioxidants; Carcinogens; Catalase; Cell Division; Female; Hyperplasia; Mice; Mice, Hairless; Ornithine Decarboxylase; Skin; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Ultraviolet Rays; Xanthine Oxidase | 1992 |
Regulation of parathyroid hormone release in normal and pathological parathyroid cells exposed to modulators of protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenoma; Animals; Calcium; Cattle; Humans; Hypercalcemia; Hyperparathyroidism; Hyperplasia; Isoquinolines; Parathyroid Diseases; Parathyroid Glands; Parathyroid Hormone; Parathyroid Neoplasms; Piperazines; Protein Kinase C; Tetradecanoylphorbol Acetate; Uremia | 1992 |
Vascular smooth muscle cell hypertrophy vs. hyperplasia. Autocrine transforming growth factor-beta 1 expression determines growth response to angiotensin II.
Topics: Angiotensin II; Animals; Cell Division; Cells, Cultured; DNA Replication; Gene Expression; Hyperplasia; Hypertrophy; In Vitro Techniques; Muscle, Smooth, Vascular; Rats; Rats, Inbred Strains; RNA, Messenger; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta | 1992 |
Comparison of the effects of four hyperplastic agents on hamster cheek pouch mucosa.
Topics: Alkynes; Animals; Cell Nucleus; Connective Tissue; Cricetinae; Cytoplasmic Granules; Diterpenes; Epithelium; Hyalin; Hyperplasia; Keratins; Male; Mouth Mucosa; Retinyl Esters; Tetradecanoylphorbol Acetate; Time Factors; Turpentine; Vitamin A | 1991 |
The chlorinated pesticide mirex is a novel nonphorbol ester-type tumor promoter in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Female; Hyperplasia; Mice; Mice, Inbred Strains; Mirex; Protein Kinase C; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1992 |
Mouse skin inflammation induced by multiple topical applications of 12-O-tetradecanoylphorbol-13-acetate.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Dermatitis, Contact; Disease Models, Animal; Ear, External; Edema; Female; Hyperplasia; Mice; Mice, Inbred Strains; Neutrophils; Skin; Tetradecanoylphorbol Acetate; Time Factors | 1991 |
Stimulatory effect of thapsigargin, a non-TPA-type tumor promoter, on arachidonic acid metabolism in the murine keratinocyte line HEL30 and on epidermal cell proliferation in vivo as compared to the effects of phorbol ester TPA.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cell Division; Cell Line; Female; Hyperplasia; Keratinocytes; Mice; Skin; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1991 |
Effects of N-acyl dehydroalanines on phorbol ester-elicited tumor development and other events in mouse skin.
Topics: Alanine; Animals; Cells, Cultured; Dinoprostone; Female; Free Radical Scavengers; Hyperplasia; Luminescent Measurements; Mice; Ornithine Decarboxylase; Oxygen; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1991 |
Prostratin, a nonpromoting phorbol ester, inhibits induction by phorbol 12-myristate 13-acetate of ornithine decarboxylase, edema, and hyperplasia in CD-1 mouse skin.
Topics: Animals; Body Water; Dose-Response Relationship, Drug; Drug Antagonism; Edema; Female; Hyperplasia; Mice; Ornithine Decarboxylase; Phorbol Esters; Skin; Tetradecanoylphorbol Acetate; Time Factors | 1991 |
The effect of the level of dietary corn oil on mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzoyl Peroxide; Capillary Permeability; Cocarcinogenesis; Corn Oil; Dietary Fats; Dinoprostone; Fatty Acids; Female; Hyperplasia; Mice; Ornithine Decarboxylase; Phospholipids; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1991 |
Stimulation of in vivo tumor growth and phorbol ester-induced inflammation by N,N-diethyl-2-[4-(phenylmethyl)phenoxy] ethanamine HCl, a potent ligand for intracellular histamine receptors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Division; Drug Synergism; Epithelium; Female; Histamine Antagonists; Hyperplasia; Inflammation; Leukemia L5178; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred DBA; Mitotic Index; Phenyl Ethers; Rats; Rats, Inbred Strains; Receptors, Histamine; Skin; Tetradecanoylphorbol Acetate | 1991 |
Modulation of phorbol ester-elicited events in mouse epidermis by dietary n-3 and n-6 fatty acids.
Topics: Animals; Capillary Permeability; Coconut Oil; Cocos; Corn Oil; Dietary Fats; Dietary Fats, Unsaturated; Epidermis; Female; Fish Oils; Hyperplasia; Mice; Phospholipids; Plant Oils; Prostaglandins E; Protein Kinase C; Tetradecanoylphorbol Acetate | 1991 |
Primary response gene expression in renal hypertrophy and hyperplasia: evidence for different growth initiation processes.
Topics: Animals; Blotting, Northern; Cell Differentiation; Cell Division; Folic Acid; Gene Expression Regulation; Genes; Hyperplasia; Hypertrophy; Kidney; Male; Mice; Mice, Inbred C57BL; Nephrectomy; Organ Size; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcriptional Activation | 1991 |
Differential down-regulation of epidermal protein kinase C by 12-O-tetradecanoylphorbol-13-acetate and diacylglycerol: association with epidermal hyperplasia and tumor promotion.
Topics: Acetone; Animals; Diglycerides; Down-Regulation; Female; Glycerides; Hyperplasia; Mice; Papilloma; Protein Kinase C; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1990 |
Onc-gene expression in hyperplasia induced by tape stripping or by topical application of TPA.
Topics: Administration, Topical; Animals; Ear; Epidermis; Guinea Pigs; Hyperplasia; Nucleic Acid Hybridization; Oncogenes; Phorbols; RNA; Tetradecanoylphorbol Acetate | 1986 |
Multistage transformation of cultured rat urothelium: the effects of N-methyl-N-nitrosourea, sodium saccharin, sodium cyclamate and 12-O-tetradecanoylphorbol-13-acetate.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Cocarcinogenesis; Cyclamates; Epithelium; Female; Hyperplasia; Methylnitrosourea; Phenotype; Rats; Rats, Inbred F344; Saccharin; Tetradecanoylphorbol Acetate; Urinary Bladder | 1986 |
Alterations in the expression of specific epidermal keratin markers in the hairless mouse by the topical application of the tumor promoters 2,3,7,8-tetrachlorodibenzo-p-dioxin and the phorbol ester 12-O-tetradecanoylphorbol-13-acetate.
Topics: Administration, Topical; Animals; Dioxins; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Epidermis; Hyperplasia; Keratins; Mice; Mice, Hairless; Molecular Weight; Polychlorinated Dibenzodioxins; Tetradecanoylphorbol Acetate | 1987 |
Histologic alterations produced by chrysarobin (1,8-dihydroxy-3-methyl-9-anthrone) in SENCAR mouse skin: relationship to skin tumor promoting activity.
Topics: Administration, Cutaneous; Animals; Anthracenes; Carcinogens; Female; Hyperplasia; Keratins; Mice; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1989 |
Effects of oral versus topical administration of cyclosporine on phorbol ester promotion of murine epidermal carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Administration, Topical; Animals; Carcinoma, Squamous Cell; Cyclosporins; Hyperplasia; Male; Mice; Neutrophils; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1989 |
Model systems for defining initiation, promotion, and progression of skin neoplasms.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogenicity Tests; Cell Division; Cocarcinogenesis; Cricetinae; Disease Models, Animal; Hyperplasia; Inflammation; Mesocricetus; Mice; Mutagenicity Tests; Neoplasms, Radiation-Induced; Salmonella typhimurium; Skin; Skin Neoplasms; Solvents; Species Specificity; Tetradecanoylphorbol Acetate; Turpentine; Ultraviolet Rays | 1989 |
Tumor initiation in mouse skin by cutting oils.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Female; Hyperplasia; Industrial Oils; Mice; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1989 |
Comparison of octahydromezerein and mezerein as protein kinase C activators and as mouse skin tumor promoters.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Diterpenes; Enzyme Activation; Female; Hyperplasia; Mice; Mice, Inbred Strains; Papilloma; Protein Kinase C; Skin; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate | 1989 |
Differential inhibition by staurosporine, a potent protein kinase C inhibitor, of 12-O-tetradecanoylphorbol-13-acetate-caused skin tumor promotion, epidermal ornithine decarboxylase induction, hyperplasia and inflammation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alkaloids; Animals; Edema; Enzyme Induction; Female; Hyperplasia; Inflammation; Kinetics; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; Protein Kinase C; Reference Values; Skin; Skin Neoplasms; Staurosporine; Superoxides; Tetradecanoylphorbol Acetate | 1989 |
Topical cyclosporine A inhibits the phorbol ester induced hyperplastic inflammatory response but not protein kinase C activation in mouse epidermis.
Topics: Administration, Topical; Animals; Arachidonic Acid; Arachidonic Acids; Cyclosporine; Cyclosporins; Dermatitis; Dinoprostone; Enzyme Activation; Epidermis; Hyperplasia; Interleukins; Mice; Mice, Hairless; Ornithine Decarboxylase; Protein Kinase C; RNA, Messenger; Tetradecanoylphorbol Acetate; Transglutaminases | 1989 |
Development of phorbol ester responsiveness in neonatal mouse epidermis: correlation between hyperplastic response and sensitivity to first-stage tumor promotion.
Topics: Animals; DNA; Female; Hyperplasia; Keratins; Mice; Mice, Inbred Strains; Mitosis; Ornithine Decarboxylase; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1985 |
Effects of retinoids on phorbol ester-stimulated epidermal DNA synthesis and hyperplasia in hairless mice.
Topics: Animals; DNA; Dose-Response Relationship, Drug; Epidermis; Female; Fluocinonide; Hyperplasia; Mice; Mice, Hairless; Retinoids; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1989 |
Neurogenic component of phorbol ester-induced mouse skin inflammation.
Topics: Administration, Topical; Animals; Diterpenes; Dose-Response Relationship, Drug; Erythema; Female; Hyperplasia; Inflammation; Mice; Mice, Inbred Strains; Phorbol Esters; Skin; Terpenes; Tetradecanoylphorbol Acetate | 1989 |
Correlation of phorbol ester promotion in the resistant C57BL/6J mouse with sustained hyperplasia but not ornithine decarboxylase or protein kinase C.
Topics: Animals; Carcinoma; Enzyme Induction; Hyperplasia; Mice; Mice, Inbred C57BL; Ornithine Decarboxylase; Papilloma; Protein Kinase C; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1989 |
Tumour-promoting and hyperplastic effects of phorbol and daphnane esters in CD-1 mouse skin and a synergistic effect of calcium ionophore with the non-promoting activator of protein kinase C, sapintoxin A.
Topics: Animals; Carcinogens; Chemical Phenomena; Chemistry; Diterpenes; Female; Hyperplasia; Phorbol Esters; Rats; Skin; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate | 1989 |
Cholera toxin, a potent inducer of epidermal hyperplasia but with no tumor promoting activity in mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cholera Toxin; Cocarcinogenesis; Cyclic AMP; Diterpenes; Enzyme Induction; Epidermis; Hyperplasia; Mice; Ornithine Decarboxylase; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate | 1986 |
Phorbol diacetate inhibits superoxide anion radical production and tumor promotion by mezerein.
Topics: Animals; Carcinogens; Diterpenes; Female; Free Radicals; Hyperplasia; Macrophages; Mice; Phorbol Esters; Skin; Skin Neoplasms; Superoxides; Terpenes; Tetradecanoylphorbol Acetate | 1986 |
Epidermal changes following application of 7,12-dimethylbenz(a)anthracene and 12-O-tetradecanoylphorbol-13-acetate to human skin transplanted to nude mice studied with histological species markers.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aged; Animals; Epidermis; Female; Humans; Hyperplasia; Male; Mice; Mice, Nude; Middle Aged; Skin Neoplasms; Skin Transplantation; Species Specificity; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 1986 |
Sebaceous adenomas with associated epidermal hyperplasia and papilloma formation as a major type of tumor induced in mouse skin by high doses of carcinogens.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoma; Animals; Carcinoma; Epidermis; Hyperplasia; Mice; Mice, Nude; Papilloma; Sebaceous Gland Neoplasms; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1986 |
Evaluation of epidermal cell kinetics following freezing or wounding of mouse skin and their potential as initiators of carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Cycle; Epidermal Cells; Female; Freezing; Hyperplasia; Mice; Mice, Inbred Strains; Skin; Skin Neoplasms; Skin Ulcer; Tetradecanoylphorbol Acetate; Time Factors; Wounds, Penetrating | 1987 |
Enhancement of mezerein-promoted papilloma formation by treatment with 12-O-tetradecanoylphorbol-13-acetate or mezerein prior to initiation.
Topics: Animals; Calcimycin; Diterpenes; Drug Synergism; Female; Hyperplasia; Mice; Papilloma; Skin; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate | 1988 |
[Epigenetic mechanism of tumor promotion. Interrelationship between inflammation and ornithine decarboxylase activity induced in vitro by the carcinogenic 12-O-tetradecanoyl-phorbol-13-acetate].
Topics: Animals; Dexamethasone; Epidermis; Female; Hyperplasia; Indomethacin; Inflammation; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; Skin Diseases; Tetradecanoylphorbol Acetate | 1988 |
In vivo effects of Sn-1,2-dioctanoylglycerol, TPA and A23187 on hamster cheek pouch epithelium.
Topics: Animals; Calcimycin; Cell Division; Cheek; Connective Tissue; Connective Tissue Cells; Cricetinae; Diglycerides; Epithelial Cells; Epithelium; Fluocinolone Acetonide; Glycerides; Hyperplasia; Male; Mesocricetus; Mitosis; Mouth Mucosa; Tetradecanoylphorbol Acetate | 1988 |
Oxidation of retinol to retinoic acid as a requirement for biological activity in mouse epidermis.
Topics: Acyclic Monoterpenes; Animals; Epidermis; Hyperplasia; Mice; Mice, Hairless; Monoterpenes; Ornithine Decarboxylase Inhibitors; Oxidation-Reduction; Terpenes; Tetradecanoylphorbol Acetate; Tretinoin; Vitamin A | 1988 |
sn-1,2-didecanoylglycerol effectively induces epidermal ornithine decarboxylase but only weak hyperplasia in mouse skin.
Topics: Administration, Cutaneous; Animals; Diglycerides; Dose-Response Relationship, Drug; Enzyme Induction; Female; Glycerides; Hyperplasia; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Ornithine Decarboxylase; Skin; Species Specificity; Tetradecanoylphorbol Acetate | 1988 |
Comparison of the effect of sn-1,2-didecanoylglycerol and 12-O-tetradecanoylphorbol-13-acetate on cutaneous morphology, inflammation and tumor promotion in CD-1 mice.
Topics: Animals; Carcinogens; Diglycerides; Edema; Enzyme Induction; Female; Glycerides; Hyperplasia; Mice; Ornithine Decarboxylase; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1988 |
Inhibition of phorbol ester-caused induction of ornithine decarboxylase and tumor promotion in mouse skin by staurosporine, a potent inhibitor of protein kinase C.
Topics: Alkaloids; Animals; Cocarcinogenesis; Enzyme Induction; Hyperplasia; Mice; Ornithine Decarboxylase; Protein Kinase C; Skin Neoplasms; Staurosporine; Tetradecanoylphorbol Acetate | 1988 |
Phorbol ester induction of 8-lipoxygenase in inbred SENCAR (SSIN) but not C57BL/6J mice correlated with hyperplasia, edema, and oxidant generation but not ornithine decarboxylase induction.
Topics: Animals; Arachidonate Lipoxygenases; Chromatography, High Pressure Liquid; Edema; Enzyme Induction; Hydroxyeicosatetraenoic Acids; Hyperplasia; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Ornithine Decarboxylase; Phorbol Esters; Prostaglandins; Skin Diseases; Tetradecanoylphorbol Acetate | 1988 |
Differential effects of phorbol esters on c-fos and c-myc and ornithine decarboxylase gene expression in mouse skin in vivo.
Topics: Animals; Female; Hyperplasia; Mice; Ornithine Decarboxylase; Phorbol Esters; Proto-Oncogenes; RNA, Messenger; Skin; Tetradecanoylphorbol Acetate | 1988 |
Bryostatin 1, an activator of protein kinase C, inhibits tumor promotion by phorbol esters in SENCAR mouse skin.
Topics: Animals; Antineoplastic Agents; Bryostatins; Enzyme Activation; Female; Hyperplasia; Lactones; Macrolides; Mice; Protein Kinase C; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1987 |
Effects of antiinflammatory agents on edema and DNA synthesis induced by 12-O-tetradecanoylphorbol-13-acetate in the guinea pig.
Topics: Animals; Anti-Inflammatory Agents; Dermatitis, Contact; DNA; Edema; Guinea Pigs; Hyperplasia; Male; Tetradecanoylphorbol Acetate | 1987 |
Effects of chronic topical application of 12-O-tetradecanoylphorbol-13-acetate on the skin and internal organs of SENCAR mice.
Topics: Administration, Topical; Amyloidosis; Animals; Female; Hyperplasia; Immune System; Male; Mice; Mice, Inbred Strains; Nephritis, Interstitial; Skin; Tetradecanoylphorbol Acetate | 1986 |
Ultrastructural analysis of epidermal hyperplasia induced by multiple 12-0-tetradecanoyl-phorbol-13-acetate (TPA) treatment of mouse skin.
Topics: Animals; Cell Differentiation; Epidermis; Female; Hyperplasia; Mice; Tetradecanoylphorbol Acetate | 1986 |
Papilloma development on young and senescent mouse skin treated with 12-O-tetradecanoylphorbol 13-acetate.
Topics: Aging; Animals; Hyperplasia; Mice; Mice, Inbred BALB C; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1985 |
The permeability of hyperplastic oral epithelium.
Topics: Animals; Cheek; Cricetinae; Epithelium; Horseradish Peroxidase; Hyperplasia; Male; Mesocricetus; Mouth Mucosa; Permeability; Peroxidases; Tetradecanoylphorbol Acetate; Tritium; Turpentine; Water | 1985 |
Mechanism of mouse skin tumor promotion by chrysarobin.
Topics: Animals; Anthracenes; Anthralin; Carcinogens; Dose-Response Relationship, Drug; Edema; Female; Hyperplasia; Mice; Ornithine Decarboxylase; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1985 |
Cutaneous changes during prolonged application of 12-O-tetradecanoylphorbol-13-acetate on mouse skin and residual effects after cessation of treatment.
Topics: Animals; Epidermis; Female; Hyperplasia; Mast Cells; Mice; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1985 |
Promotion of epidermal carcinogenesis by repeated damage to mouse skin.
Topics: Age Factors; Animals; Carcinogens; Female; Hyperplasia; Mice; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1985 |