tetradecanoylphorbol acetate has been researched along with Granulomatous Disease, Chronic in 108 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 50 (46.30) | 18.7374 |
| 1990's | 36 (33.33) | 18.2507 |
| 2000's | 15 (13.89) | 29.6817 |
| 2010's | 7 (6.48) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bernuth, HV; Brinkmann, V; Herzig, A; Kenny, EF; Krüger, R; Mondal, S; Muth, A; Thompson, PR; Zychlinsky, A | 1 |
| Adcock, IM; Garssen, J; Mansouri, D; Marjani, M; Mehrian, P; Moniri, A; Mortaz, E; Roos, D; Sarhifynia, S; Tabarsi, P; van Leeuwen, K | 1 |
| Münz, C; Nytko, KJ; Reichenbach, J; Romao, S; Siler, U; Tejera, E | 1 |
| Dimopoulou, M; Goussetis, E; Graphakos, S; Kitra, V; Kokkali, G; Konialis, CP; Pangalos, CG; Pantos, K; Papassavas, A; Peristeri, I; Petrakou, E; Petropoulou, T; Spiropoulos, A; Tzanoudaki, M; Vessalas, G | 1 |
| Asselbergh, B; De Rycke, R; Delforge, M; Noppen, S; Parthoens, E; Remijsen, Q; Vanden Berghe, T; Vandenabeele, P; Willems, J; Wirawan, E | 1 |
| Adachi, S; Arai, T; Nishinaka, Y; Takaori-Kondo, A; Yamashita, K | 1 |
| Chapple, IL; Cooper, PR; Huissoon, A; Ling, MR; Palmer, LJ; Wright, HJ | 1 |
| Geiszt, M; Ligeti, E; Nemet, K; Rada, BK; Roos, D; Van Bruggen, R | 1 |
| Német, K; Selmeczy, Z; Szelényi, J; Vizi, ES | 1 |
| Bordigoni, P; Bost-Bru, C; Brion, JP; Durant-Vital, D; Floret, D; Gatel, P; Guillot, M; Li, XJ; Maquet, E; Martel, C; Michel, G; Morel, F; Stasia, MJ; Voelckel, MA | 1 |
| Huang, YF; Lin, CH; Shieh, CC; Wu, YC | 1 |
| Cherny, VV; DeCoursey, TE; Katz, BZ; Morgan, D; Murphy, R | 1 |
| Ayatollahi, M; Geramizadeh, B | 1 |
| Alfinito, F; Barone, L; Becchimanzi, C; Cacciapuoti, C; Rotoli, B; Ruggiero, G; Sica, M; Terrazzano, G | 1 |
| Ayatollahi, M; Haghshenas, M; Kashef, S; Ramzi, M; Tabei, Z | 1 |
| Abed, U; Brinkmann, V; Fuchs, TA; Goosmann, C; Hurwitz, R; Schulze, I; Wahn, V; Weinrauch, Y; Zychlinsky, A | 1 |
| Parvaneh, N; Teimourian, S | 1 |
| McPhail, LC; Snyderman, R | 1 |
| Chapman, CE; Chovaniec, ME; Cohen, HJ; Simons, ER; Whitin, JC | 1 |
| Gallin, JI; Seligmann, BE | 1 |
| Chovaniec, ME; Cohen, HJ; Kruskall, MS; Newburger, PE; Rappeport, JM; Robinson, SH | 1 |
| Carp, H; Janoff, A | 1 |
| Clark, RA; Szot, S | 2 |
| Fletcher, MP; Gallin, JI; Seligmann, BE | 1 |
| Johnston, RB; McPhail, LC; Musson, RA; Shafran, H | 1 |
| English, D; Lukens, JN | 1 |
| Bonvini, E; Dallegri, F; Gahrton, G; Holm, G; Patrone, F; Sacchetti, C | 1 |
| Green, TR; Wirtz, MK; Wu, DE | 1 |
| Bellavite, P; Della Bianca, V; Dri, P; Serra, MC | 1 |
| Donowitz, GR; Kay, HD; Mandell, GL; Smith, DL; Sullivan, G | 1 |
| Arbeter, AM; Douglas, SD; Ihara, T; Ito, M; Starr, SE | 1 |
| Bellavite, P; Bianco, P; D'Amelio, R; de Sole, P; Le Moli, S; Lippa, S; Rocchi, G; Rossi, F; Seminara, R; Vercelli, B | 1 |
| Harvey, BA; Levinsky, RJ; Rodeck, CH; Soothill, JF | 1 |
| Johansen, KS | 1 |
| Castranova, V; Jones, GS; Peden, D; Phillips, RM; Vandyke, K | 1 |
| Andrews, PC; Babior, BM | 1 |
| Conkling, PR; Klassen, DK; Sagone, AL | 1 |
| McMurtry, I; Repine, JE; Shasby, DM; Shasby, SS; Tate, RM; Vanbenthuysen, KM | 1 |
| Biggar, WD; Birnboim, HC | 1 |
| DeChatelet, LR; Shirley, PS | 1 |
| Chused, TM; Gallin, JI; Seligmann, B | 1 |
| Babior, BM; el Benna, J; Ruedi, JM | 1 |
| Badwey, JA; Curnutte, JT; Ding, J; Erickson, RW | 1 |
| Balducci, L; Del Principe, D; Digilio, G; Iacobini, M; Palumbo, G; Torre, A | 1 |
| Curnutte, JT; Grinstein, S; Nanda, A | 2 |
| Dusi, S; Rossi, F | 1 |
| Kuratsuji, T; Mizunari, H; Namiki, H; Tsunawaki, S | 1 |
| Badwey, JA; Balazovich, KJ; Curnutte, JT; Ding, J; Erickson, RW | 1 |
| Belohradsky, BH; Buth, S; Gahr, M; Jendrossek, V; Liese, J; Peters, AM; Wintergerst, U | 1 |
| Collins, MK; Kinnon, C; Levinsky, RJ; Parkar, MH; Porter, CD | 1 |
| Ank, BJ; Fanger, MW; Roberts, RL; Shen, L; Stiehm, ER | 1 |
| Bellinati-Pires, R; Carneiro-Sampaio, MM; Salgado, MM; Waitzberg, DL | 1 |
| Dahlgren, C; Follin, P; Khalfan, L; Lundqvist, H | 1 |
| Donini, M; Dusi, S; Rossi, F | 1 |
| Atkinson, TP; Berkow, RL; Bonitatibus, GM | 1 |
| Gahr, M; Heyden, S; Jendrossek, V; Neubauer, B; Ritzel, A | 1 |
| Ahlin, A; Elinder, G; Palmblad, J | 1 |
| Farkas, L; Geiszt, M; Kapus, A; Ligeti, E; Német, K | 1 |
| Boyd, NA; Crockard, AD; Haughton, DJ; McCluskey, DR; Thompson, JM; Turner, CP | 1 |
| Greve, J; Otto, C; Sijtsema, NM | 1 |
| Donini, M; Dusi, S; Giacca, M; Nadalini, KA; Roos, D; Rossi, F; Wientjes, FB; Zentilin, L | 1 |
| Ahlin, A; Fadeel, B; Hampton, MB; Henter, JI; Orrenius, S | 1 |
| Ahlin, A; Bernatowska, E; de Boer, M; Eppink, MH; Goldblatt, D; Hilarius, PM; Leusen, JH; Meischl, C; Palmblad, J; Roos, D; Sanders, L; Skopczynska, H; van Berkel, WJ; Verhoeven, AJ; Weening, RS | 1 |
| De Boer, M; Hack, WW; Kuijpers, TW; Neefjes, VM; Roos, D; Weening, RS | 1 |
| Holland, SM; Lavigne, MC; Leto, TL; Malech, HL | 1 |
| Cherny, VV; DeCoursey, TE; Dinauer, MC; Katz, BZ; Morgan, D | 1 |
| Bordigoni, P; Demaurex, N; Lardy, B; Martel, C; Maturana, A; Morel, F; Rousseau, P; Stasia, MJ | 1 |
| Borregaard, N; Esmann, V; Johansen, KS | 1 |
| Rasmussen, B; Repine, JE; White, JG | 1 |
| Clawson, CC; Holmes, B; Repine, JE; White, JG | 1 |
| Chase, MJ; Klebanoff, SJ | 1 |
| Gallin, JI; Nath, J; Ohno, Y; Wright, DG | 1 |
| Blackwood, LL; Chong, HO; Epling, CL; McHugh, TM; Stites, DP; Wara, DW | 1 |
| Champion, GD; Graham, GG; Rudkowski, R; Ziegler, JB | 1 |
| Gibbs, L; Kaslovsky, RA; Malik, AB | 1 |
| Curnutte, JT; Dinauer, MC; Erickson, RW; Messner, H; Muhlebach, TJ; Orkin, SH; Pierce, EA; Seger, RA | 1 |
| Emmendörffer, A; Lohmann-Matthes, ML; Roesler, J | 1 |
| Ank, BJ; Roberts, RL; Stiehm, ER | 2 |
| Belkowski, LS; Bloom, BR; Goldberg, M | 1 |
| Babior, BM; Curnutte, JT; Mayo, LA; Okamura, N; Peveri, P; Smith, RM | 1 |
| Fluit, AC; Miltenburg, LA; van Kats-Renaud, HJ; van Kessel, KP; van Strijp, JA; Verhoef, J | 1 |
| Leto, TL; Rotrosen, D | 1 |
| Hasui, M; Hirabayashi, Y; Kobayashi, Y; Komiyama, Y; Masuda, M; Murakami, T; Murata, K | 1 |
| Emmendörffer, A; Hecht, M; Lohmann-Matthes, ML; Roesler, J | 1 |
| Gallin, JI; Ohno, Y; Roberts, RL | 1 |
| Hamasaki, T; Kobayashi, M; Sakano, T; Sakura, N; Ueda, K; Usui, T | 1 |
| Landay, AL; Rothberg, L; Zeller, JM | 1 |
| Ezekowitz, RA; Newburger, PE; Orkin, SH | 1 |
| Clark, RA; el-Hag, A | 1 |
| Lichtenstein, A | 1 |
| Garcia, RC; Segal, AW | 1 |
| Harvey, B; Levinsky, R; Nicolaides, K; Rodeck, C | 1 |
| Bender, JG; Chenoweth, DE; Steinkamp, JA; Van Epps, DE | 1 |
| Campbell, DE; Douglas, SD; Hassan, NF | 2 |
| Andrews, PC; Babior, BM; Hayakawa, T; Suzuki, K; Suzuki, S | 1 |
| Barkley, R; Curtis, WE; Linas, SL; Muldrow, ME; Parker, NB; Repine, JE | 1 |
| Brown, EJ; Frank, MM; Gallin, JI; Metcalf, JA; O'Shea, JJ; Seligmann, BE | 1 |
| Roos, D; van Schaik, ML; Verhoeven, AJ; Weening, RS | 1 |
| Kramer, IM; Roos, D; van der Bend, RL; Verhoeven, AJ; Weening, RS | 1 |
| Babior, BM; Curnutte, JT; Okamura, N; Roberts, RL | 1 |
| Amit, N; Hakim, J; Marquetty, C; Pham Huu, T | 1 |
| Duque, RE; Ward, PA | 1 |
| De Mattia, D; Fumarulo, R; Giordano, D; Lovecchio, T; Riccardi, S; Santoro, N; Schettini, F | 1 |
| Hirabayashi, Y; Kobayashi, Y; Taniuchi, S | 1 |
1 trial(s) available for tetradecanoylphorbol acetate and Granulomatous Disease, Chronic
| Article | Year |
|---|---|
Dose-dependent enhancements by interferon-gamma on functional responses of neutrophils from chronic granulomatous disease patients.
Topics: Adolescent; Adult; Aspergillus; Child; Dose-Response Relationship, Drug; Double-Blind Method; Female; Granulomatous Disease, Chronic; Humans; In Vitro Techniques; Interferon-gamma; Kinetics; Luminescent Measurements; Male; Membrane Glycoproteins; N-Formylmethionine Leucyl-Phenylalanine; NADH Dehydrogenase; NADPH Dehydrogenase; NADPH Oxidase 2; NADPH Oxidases; Neutrophils; Phagocytosis; Phosphoproteins; Recombinant Proteins; Superoxides; Tetradecanoylphorbol Acetate; Time Factors | 1997 |
107 other study(ies) available for tetradecanoylphorbol acetate and Granulomatous Disease, Chronic
| Article | Year |
|---|---|
Diverse stimuli engage different neutrophil extracellular trap pathways.
Topics: Calcimycin; Candida albicans; Extracellular Traps; Granulomatous Disease, Chronic; Healthy Volunteers; Humans; Metabolic Networks and Pathways; Neutrophils; Nigericin; Streptococcus; Tetradecanoylphorbol Acetate | 2017 |
An adult autosomal recessive chronic granulomatous disease patient with pulmonary Aspergillus terreus infection.
Topics: Adrenal Cortex Hormones; Adult; Aspergillus; Base Sequence; Bronchoalveolar Lavage Fluid; DNA Mutational Analysis; DNA, Fungal; Granulomatous Disease, Chronic; Humans; Lung; Male; Neutrophils; Reactive Oxygen Species; Respiratory Tract Infections; Rhodamines; Tetradecanoylphorbol Acetate; Tomography, X-Ray Computed | 2018 |
Defective nuclear entry of hydrolases prevents neutrophil extracellular trap formation in patients with chronic granulomatous disease.
Topics: Adenine; Androstadienes; Benzylamines; Candida albicans; Cell Nucleus; Extracellular Traps; Granulomatous Disease, Chronic; Histones; Humans; Hydrolases; Neutrophils; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Quinazolines; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Wortmannin | 2015 |
Successful hematopoietic stem cell transplantation in 2 children with X-linked chronic granulomatous disease from their unaffected HLA-identical siblings selected using preimplantation genetic diagnosis combined with HLA typing.
Topics: Blood Platelets; Bone Marrow Cells; Cell Count; Child, Preschool; Embryo, Mammalian; Female; Fertilization in Vitro; Fetal Blood; Graft Survival; Granulomatous Disease, Chronic; Hematopoietic Stem Cell Transplantation; Histocompatibility Testing; HLA Antigens; Humans; Male; Membrane Glycoproteins; Mutation, Missense; NADPH Oxidase 2; NADPH Oxidases; Neutrophils; Preimplantation Diagnosis; Respiratory Burst; Siblings; Superoxides; Tetradecanoylphorbol Acetate; Transplantation Chimera; Treatment Outcome | 2010 |
Neutrophil extracellular trap cell death requires both autophagy and superoxide generation.
Topics: Apoptosis; Autophagy; Chromatin Assembly and Disassembly; Granulomatous Disease, Chronic; Humans; Membrane Glycoproteins; NADH, NADPH Oxidoreductases; NADPH Oxidase 2; NADPH Oxidases; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate | 2011 |
Singlet oxygen is essential for neutrophil extracellular trap formation.
Topics: Antipyrine; Cells, Cultured; Dihematoporphyrin Ether; Edaravone; Free Radical Scavengers; Granulomatous Disease, Chronic; Humans; Neutrophils; Singlet Oxygen; Tetradecanoylphorbol Acetate | 2011 |
Hypochlorous acid regulates neutrophil extracellular trap release in humans.
Topics: Antimicrobial Cationic Peptides; Blood Bactericidal Activity; Chromatin; Cytochalasin B; Cytoplasmic Granules; Granulomatous Disease, Chronic; Humans; Hydrogen Peroxide; Hypochlorous Acid; NADPH Oxidases; Neutrophils; Opsonin Proteins; Peroxidase; Phagocytosis; Reactive Oxygen Species; Staphylococcus aureus; Superoxide Dismutase; Taurine; Tetradecanoylphorbol Acetate | 2012 |
Calcium signalling is altered in myeloid cells with a deficiency in NADPH oxidase activity.
Topics: Calcium; Calcium Signaling; Cell Line; Cells, Cultured; Enzyme Inhibitors; Granulomatous Disease, Chronic; Humans; Leukemia, Promyelocytic, Acute; Manganese; Membrane Potentials; Myeloid Cells; NADPH Oxidases; Neutrophils; Nitric Oxide Synthase; Onium Compounds; Superoxides; Tetradecanoylphorbol Acetate | 2003 |
The inducibility of TNF-alpha production is different in the granulocytic and monocytic differentiated forms of wild type and CGD-mutant PLB-985 cells.
Topics: Cell Differentiation; Cell Line, Tumor; Cells, Cultured; Granulocytes; Granulomatous Disease, Chronic; Humans; Lipopolysaccharide Receptors; Lipopolysaccharides; Macrophages; Monocytes; Mutation; N-Formylmethionine Leucyl-Phenylalanine; Receptors, Cell Surface; Receptors, Complement 3b; Receptors, IgG; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Zymosan | 2003 |
Characterization of six novel mutations in the CYBB gene leading to different sub-types of X-linked chronic granulomatous disease.
Topics: Genotype; Granulomatous Disease, Chronic; Humans; Immunoblotting; Male; Membrane Glycoproteins; Mutation; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidase 2; NADPH Oxidases; Phenotype; Tetradecanoylphorbol Acetate | 2005 |
Detection of defective granulocyte function with flow cytometry in newborn infants.
Topics: Flow Cytometry; Granulocytes; Granulomatous Disease, Chronic; Humans; Infant, Newborn; Luminescent Measurements; Reactive Oxygen Species; Respiratory Burst; Tetradecanoylphorbol Acetate | 2005 |
The pH dependence of NADPH oxidase in human eosinophils.
Topics: Adult; Enzyme Activation; Eosinophils; Granulomatous Disease, Chronic; Humans; Hydrogen-Ion Concentration; Membrane Potentials; NADPH Oxidases; Patch-Clamp Techniques; Respiratory Burst; Tetradecanoylphorbol Acetate | 2005 |
Carrier screening and prenatal detection of chronic granulomatous disease in Iran.
Topics: Adult; Diagnosis, Differential; Female; Fetal Blood; Genetic Carrier Screening; Granulomatous Disease, Chronic; Humans; Infant; Infant, Newborn; Iran; Male; Mass Screening; Nitroblue Tetrazolium; Pregnancy; Prenatal Diagnosis; Superoxides; Tetradecanoylphorbol Acetate | 2006 |
Glycosyl-phosphatidyl-inositol-defective granulocytes from paroxysmal nocturnal haemoglobinuria patients show increased bacterial ingestion but reduced respiratory burst induction.
Topics: Adult; Animals; Carcinogens; Cells, Cultured; Enzyme Activation; Escherichia coli; Glycosylphosphatidylinositols; Granulocytes; Granulomatous Disease, Chronic; Hematopoiesis; Hemoglobinuria, Paroxysmal; Humans; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutropenia; Phagocytosis; Protein Kinase C; Respiratory Burst; Tetradecanoylphorbol Acetate | 2007 |
A fast and easy nitroblue tetrazolium method for carrier screening and prenatal detection of chronic granulomatous disease.
Topics: Child, Preschool; Female; Fetal Blood; Granulomatous Disease, Chronic; Heterozygote; Humans; Indicators and Reagents; Infant; Infant, Newborn; Male; Microscopy; Neutrophils; Nitroblue Tetrazolium; Phagocytosis; Pregnancy; Prenatal Diagnosis; Tetradecanoylphorbol Acetate | 2006 |
Novel cell death program leads to neutrophil extracellular traps.
Topics: Antibodies; Apoptosis; Catalase; Cell Death; Cell Survival; Chromatin; Cytoplasmic Granules; Enzyme Inhibitors; fas Receptor; Granulomatous Disease, Chronic; Humans; Hydrogen Peroxide; Immunity, Innate; Leukocyte Elastase; Microscopy, Electron; NADPH Oxidases; Neutrophil Activation; Neutrophils; Nuclear Envelope; Onium Compounds; Phagocytosis; Reactive Oxygen Species; Staphylococcus aureus; Tetradecanoylphorbol Acetate; Vacuoles | 2007 |
Effectiveness of nitroblue tetrazolium (NBT) test.
Topics: Child, Preschool; Female; Fetal Blood; Granulomatous Disease, Chronic; Heterozygote; Humans; Indicators and Reagents; Infant; Infant, Newborn; Male; Microscopy; Neutrophils; Nitroblue Tetrazolium; Phagocytosis; Pregnancy; Prenatal Diagnosis; Tetradecanoylphorbol Acetate | 2008 |
Mechanisms of regulating the respiratory burst in leukocytes.
Topics: Animals; Arachidonic Acids; Calcimycin; Calcium; Cytoplasmic Granules; Electric Conductivity; Granulomatous Disease, Chronic; Humans; Leukocytes; Membrane Potentials; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Nucleotides, Cyclic; Oxygen Consumption; Peroxidase; Protein Kinases; Tetradecanoylphorbol Acetate | 1984 |
Correlation between membrane potential changes and superoxide production in human granulocytes stimulated by phorbol myristate acetate. Evidence for defective activation in chronic granulomatous disease.
Topics: Catalase; Granulocytes; Granulomatous Disease, Chronic; Humans; Membrane Potentials; Oxygen; Phorbols; Potassium; Spectrometry, Fluorescence; Superoxide Dismutase; Superoxides; Tetradecanoylphorbol Acetate; Valinomycin | 1980 |
Use of lipophilic probes of membrane potential to assess human neutrophil activation. Abnormality in chronic granulomatous disease.
Topics: Adolescent; Adult; Calcimycin; Carbocyanines; Chediak-Higashi Syndrome; Chemotactic Factors; Chemotaxis, Leukocyte; Child; Child, Preschool; Female; Granulomatous Disease, Chronic; Humans; In Vitro Techniques; Male; Membrane Potentials; Neutrophils; Onium Compounds; Superoxides; Tetradecanoylphorbol Acetate; Tetraphenylborate; Trityl Compounds; Valinomycin | 1980 |
Chronic granulomatous disease. Expression of the metabolic defect by in vitro culture of bone marrow progenitors.
Topics: Adolescent; Adult; Blood Bactericidal Activity; Bone Marrow Cells; Cells, Cultured; Female; Granulomatous Disease, Chronic; Hematopoietic Stem Cells; Humans; Male; Nitroblue Tetrazolium; Opsonin Proteins; Oxidation-Reduction; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1980 |
Potential mediator of inflammation. Phagocyte-derived oxidants suppress the elastase-inhibitory capacity of alpha 1-proteinase inhibitor in vitro.
Topics: alpha 1-Antitrypsin; Glucose Oxidase; Granulomatous Disease, Chronic; Humans; Immunoelectrophoresis; Macrophages; Monocytes; Neutrophils; Oxidation-Reduction; Pancreatic Elastase; Peroxidase; Tetradecanoylphorbol Acetate | 1980 |
The myeloperoxidase-hydrogen peroxide-halide system as effector of neutrophil-mediated tumor cell cytotoxicity.
Topics: Animals; Antioxidants; Bromides; Chlorides; Cytotoxicity, Immunologic; Granulomatous Disease, Chronic; Humans; Hydrogen Peroxide; Iodides; Lymphoma; Mice; Neutrophils; Peroxidase; Peroxidases; Proteins; Tetradecanoylphorbol Acetate | 1981 |
Correlation of human neutrophil secretion, chemoattractant receptor mobilization, and enhanced functional capacity.
Topics: 1-Butanol; Butanols; Calcimycin; Calcium; Chemotaxis, Leukocyte; Cycloheximide; Cytoplasmic Granules; Granulomatous Disease, Chronic; Humans; Hydrogen Peroxide; Lactoferrin; Methionine; Muramidase; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Pinocytosis; Puromycin; Receptors, Immunologic; Superoxides; Tetradecanoylphorbol Acetate | 1982 |
Chemotactic factor inactivation by stimulated human neutrophils mediated by myeloperoxidase-catalyzed methionine oxidation.
Topics: Aminopeptidases; Candidiasis; Catalysis; Chemotactic Factors; Complement C5; Complement C5a; Granulomatous Disease, Chronic; Humans; Methionine; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Peroxidase; Peroxidases; Sulfides; Tetradecanoylphorbol Acetate; Zymosan | 1982 |
Differences in the ability of human peripheral blood monocytes and in vitro monocyte-derived macrophages to produce superoxide anion: studies with cells from normals and patients with chronic granulomatous disease.
Topics: Adult; Calcimycin; Cells, Cultured; Female; Granulomatous Disease, Chronic; Humans; Infant; Macrophages; Male; Monocytes; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Oligopeptides; Opsonin Proteins; Oxygen; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1982 |
Regulation of neutrophil inflammatory mediator release: chemotactic peptide activation of stimulus-dependent cytotoxicity.
Topics: Chemotactic Factors; Chromium Radioisotopes; Cytotoxicity, Immunologic; Granulomatous Disease, Chronic; Humans; Hydrogen Peroxide; Inflammation; Interleukin-8; Male; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Peroxidase; Tetradecanoylphorbol Acetate | 1983 |
Ox erythrocyte cytotoxicity by phorbol myristate acetate-activated human neutrophils.
Topics: Animals; Cattle; Child; Child, Preschool; Cytotoxicity, Immunologic; Erythrocytes; Female; Granulomatous Disease, Chronic; Humans; Hydrogen Peroxide; Male; Neutrophils; Oxygen; Peroxidase; Phorbols; Tetradecanoylphorbol Acetate | 1983 |
Delineation of the catalytic components of the NADPH-dependent O2- generating oxidoreductase of human neutrophils.
Topics: Cytochrome Reductases; Granulomatous Disease, Chronic; Humans; Kinetics; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Quinone Reductases; Reference Values; Superoxides; Tetradecanoylphorbol Acetate | 1983 |
The measurement of superoxide anion production by granulocytes In whole blood. A clinical test for the evaluation of phagocyte function and serum opsonic capacity.
Topics: Female; Granulocytes; Granulomatous Disease, Chronic; Humans; Male; Opsonin Proteins; Phagocytosis; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1983 |
Evidence for a nonoxidative mechanism of human natural killer (NK) cell cytotoxicity by using mononuclear effector cells from healthy donors and from patients with chronic granulomatous disease.
Topics: Cell Differentiation; Cytochrome c Group; Cytotoxicity, Immunologic; Granulomatous Disease, Chronic; Humans; Killer Cells, Natural; Luminescent Measurements; Monocytes; Neutrophils; Nitroblue Tetrazolium; Tetradecanoylphorbol Acetate; Zymosan | 1983 |
Human polymorphonuclear leukocyte-mediated cytotoxicity against varicella-zoster virus-infected fibroblasts.
Topics: Adult; Antibodies, Viral; Antibody-Dependent Cell Cytotoxicity; Catalase; Child; Female; Fibroblasts; Granulomatous Disease, Chronic; Herpes Zoster; Herpesvirus 3, Human; Humans; Infant, Newborn; Male; Neutrophils; Tetradecanoylphorbol Acetate | 1984 |
Chronic granulomatous disease in two sisters.
Topics: Adolescent; Blood Bactericidal Activity; Child; Consanguinity; Female; Granulomatous Disease, Chronic; Humans; Lymph Nodes; Neutrophils; Nitroblue Tetrazolium; Spleen; Staphylococcus aureus; Superoxides; Tetradecanoylphorbol Acetate | 1984 |
Phorbol myristate acetate stimulated NBT test: a simple method suitable for antenatal diagnosis of chronic granulomatous disease.
Topics: Adolescent; Adult; Child; Child, Preschool; Endotoxins; Escherichia coli; Female; Genetic Carrier Screening; Granulomatous Disease, Chronic; Humans; Infant; Male; Nitroblue Tetrazolium; Phorbols; Pregnancy; Prenatal Diagnosis; Tetradecanoylphorbol Acetate; Tetrazolium Salts | 1983 |
Nitroblue tetrazolium slide test. Use of the phorbol-myristate-acetate-stimulated NBT-reduction slide test for routine and prenatal detection of chronic granulomatous disease and diagnosis of heterozygous carriers.
Topics: Female; Fetal Diseases; Genetic Carrier Screening; Glucose; Granulocytes; Granulomatous Disease, Chronic; Humans; Luminescent Measurements; Male; Nitroblue Tetrazolium; Oxidation-Reduction; Phagocytosis; Pregnancy; Prenatal Diagnosis; Staphylococcus aureus; Tetradecanoylphorbol Acetate; Tetrazolium Salts | 1983 |
Abnormal responses of granulocytes in chronic granulomatous disease.
Topics: Calcimycin; Chemotactic Factors; Concanavalin A; Granulocytes; Granulomatous Disease, Chronic; Humans; In Vitro Techniques; Membrane Potentials; Tetradecanoylphorbol Acetate | 1981 |
Endogenous protein phosphorylation by resting and activated human neutrophils.
Topics: Digitonin; Granulomatous Disease, Chronic; Humans; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Phosphoproteins; Phosphorylation; Tetradecanoylphorbol Acetate; Zymosan | 1983 |
Activation of monocyte and granulocyte antibody-dependent cytotoxicity by phorbol myristate acetate.
Topics: Antibody-Dependent Cell Cytotoxicity; Catalase; Cell Division; Cell Line; Dose-Response Relationship, Drug; Granulomatous Disease, Chronic; Hexosephosphates; Humans; Lymphocytes; Monocytes; Neutrophils; Oxygen; Phorbols; Tetradecanoylphorbol Acetate | 1982 |
Granulocytes mediate acute edematous lung injury in rabbits and in isolated rabbit lungs perfused with phorbol myristate acetate: role of oxygen radicals.
Topics: Agranulocytosis; Animals; Free Radicals; Granulocytes; Granulomatous Disease, Chronic; Lung; Lung Injury; Mechlorethamine; Oxygen; Perfusion; Phorbols; Pulmonary Edema; Rabbits; Serum Albumin, Bovine; Sodium Chloride; Tetradecanoylphorbol Acetate | 1982 |
Failure of phorbol myristate acetate to damage DNA in leukocytes from patients with chronic granulomatous disease.
Topics: DNA; Granulomatous Disease, Chronic; Humans; Leukocytes; Phorbols; Tetradecanoylphorbol Acetate | 1982 |
Evaluation of chronic granulomatous disease by a chemiluminescence assay of microliter quantities of whole blood.
Topics: Child; Granulomatous Disease, Chronic; Humans; Luminescent Measurements; Luminol; Microchemistry; Neutrophils; Oxygen Consumption; Tetradecanoylphorbol Acetate; Zymosan | 1981 |
Human neutrophil heterogeneity identified using flow microfluorometry to monitor membrane potential.
Topics: Calcium; Cell Membrane; Flow Cytometry; Granulomatous Disease, Chronic; Humans; Magnesium; Membrane Potentials; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Tetradecanoylphorbol Acetate | 1981 |
Cytosolic guanine nucleotide-binding protein Rac2 operates in vivo as a component of the neutrophil respiratory burst oxidase. Transfer of Rac2 and the cytosolic oxidase components p47phox and p67phox to the submembranous actin cytoskeleton during oxidase
Topics: Actins; Adult; Cell Membrane; Cytoskeleton; Granulomatous Disease, Chronic; GTP-Binding Proteins; Humans; In Vitro Techniques; NADH, NADPH Oxidoreductases; NADPH Dehydrogenase; NADPH Oxidases; Neutrophils; Phosphoproteins; rac GTP-Binding Proteins; Superoxides; Tetradecanoylphorbol Acetate | 1994 |
Reciprocal interactions between protein kinase C and components of the NADPH oxidase complex may regulate superoxide production by neutrophils stimulated with a phorbol ester.
Topics: Amino Acid Sequence; Biological Transport; Detergents; Granulomatous Disease, Chronic; Humans; In Vitro Techniques; Molecular Sequence Data; NADH, NADPH Oxidoreductases; NADPH Dehydrogenase; NADPH Oxidases; Neutrophils; Octoxynol; Oxygen; Phosphoprotein Phosphatases; Phosphoproteins; Protein Kinase C; Protein Kinase Inhibitors; Superoxides; Tetradecanoylphorbol Acetate | 1994 |
Study of chronic granulomatous disease by a nitroblue tetrazolium densitometric kinetic test: a new research method.
Topics: Adult; Child, Preschool; Cytochrome c Group; Densitometry; Female; Formazans; Genetic Linkage; Granulomatous Disease, Chronic; Humans; Kinetics; Male; Neutrophils; Nitroblue Tetrazolium; Oxidation-Reduction; Reagent Kits, Diagnostic; Reference Values; Spectrophotometry; Superoxides; Tetradecanoylphorbol Acetate; X Chromosome | 1993 |
Activation of H+ conductance in neutrophils requires assembly of components of the respiratory burst oxidase but not its redox function.
Topics: Female; Granulomatous Disease, Chronic; Humans; Ion Transport; Male; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Oxidation-Reduction; Point Mutation; Protons; Respiratory Burst; Tetradecanoylphorbol Acetate | 1994 |
Activation of NADPH oxidase of human neutrophils involves the phosphorylation and the translocation of cytosolic p67phox.
Topics: Cytosol; Enzyme Activation; Granulomatous Disease, Chronic; Humans; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Phosphoproteins; Phosphorylation; Reference Values; Tetradecanoylphorbol Acetate | 1993 |
NADPH-binding component of the respiratory burst oxidase system: studies using neutrophil membranes from patients with chronic granulomatous disease lacking the beta-subunit of cytochrome b558.
Topics: Affinity Labels; Binding Sites; Biological Transport; Cell Membrane; Cytochrome b Group; Genetic Linkage; Granulomatous Disease, Chronic; Humans; In Vitro Techniques; NADH, NADPH Oxidoreductases; NADP; NADPH Oxidases; Neutrophils; Tetradecanoylphorbol Acetate; X Chromosome | 1994 |
Protein kinases potentially capable of catalyzing the phosphorylation of p47-phox in normal neutrophils and neutrophils of patients with chronic granulomatous disease.
Topics: Amino Acid Sequence; Blotting, Western; Granulomatous Disease, Chronic; Humans; Isoenzymes; Molecular Sequence Data; NADPH Dehydrogenase; NADPH Oxidases; Neutrophils; Oligopeptides; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein Kinases; Tetradecanoylphorbol Acetate | 1993 |
Improvement of superoxide production in monocytes from patients with chronic granulomatous disease by recombinant cytokines.
Topics: Cells, Cultured; Cytokines; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Granulomatous Disease, Chronic; Humans; Interferon-gamma; Interleukin-1; Interleukin-3; Male; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Recombinant Proteins; Superoxides; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1993 |
X-linked chronic granulomatous disease: correction of NADPH oxidase defect by retrovirus-mediated expression of gp91-phox.
Topics: B-Lymphocytes; Base Sequence; Cell Line; Cytochrome b Group; DNA Primers; Erythrocytes; Gene Transfer Techniques; Granulomatous Disease, Chronic; HeLa Cells; Herpesvirus 4, Human; Humans; Kinetics; Luminescent Measurements; Macromolecular Substances; Membrane Glycoproteins; Molecular Sequence Data; NADH, NADPH Oxidoreductases; NADPH Oxidase 2; NADPH Oxidases; Neutrophils; Polymerase Chain Reaction; Retroviridae; Simian virus 40; Superoxides; TATA Box; Tetradecanoylphorbol Acetate; Transduction, Genetic; X Chromosome | 1993 |
Abnormal activation of H+ conductance in NADPH oxidase-defective neutrophils.
Topics: Biological Transport, Active; Enzyme Activation; Female; Free Radicals; Granulomatous Disease, Chronic; Heterozygote; Humans; Hydrogen-Ion Concentration; Male; NADH, NADPH Oxidoreductases; NADP; NADPH Oxidases; Neutrophils; Oxygen; Proton Pumps; Sodium; Tetradecanoylphorbol Acetate | 1993 |
Role of oxygen intermediates in cytotoxicity: studies in chronic granulomatous disease.
Topics: Animals; Antibody-Dependent Cell Cytotoxicity; Chickens; Cytotoxicity, Immunologic; Free Radicals; Granulomatous Disease, Chronic; Humans; Mice; Monocytes; Neutrophils; Oxygen; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Functional alterations of human neutrophils by medium-chain triglyceride emulsions: evaluation of phagocytosis, bacterial killing, and oxidative activity.
Topics: Adolescent; Adult; Child; Dose-Response Relationship, Drug; Emulsions; Fatty Acids; Granulomatous Disease, Chronic; Humans; Hydrogen Peroxide; In Vitro Techniques; Kinetics; Lipopolysaccharides; Male; Neutrophils; Phagocytosis; Reference Values; Staphylococcus aureus; Tetradecanoylphorbol Acetate; Triglycerides | 1993 |
Phorbol myristate acetate-induced NADPH oxidase activity in human neutrophils: only half the story has been told.
Topics: Adult; Cell Differentiation; Cell Membrane; Enzyme Induction; Fetal Blood; Fluoresceins; Granulomatous Disease, Chronic; HL-60 Cells; Humans; Hydrogen Peroxide; Luminescent Measurements; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Oxygen Consumption; Peroxidase; Respiratory Burst; Subcellular Fractions; Tetradecanoylphorbol Acetate | 1996 |
Mechanisms of NADPH oxidase activation in human neutrophils: p67phox is required for the translocation of rac 1 but not of rac 2 from cytosol to the membranes.
Topics: Blotting, Western; Cell Membrane; Concanavalin A; Cytoplasm; Granulomatous Disease, Chronic; GTP-Binding Proteins; Humans; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Phosphoproteins; rac GTP-Binding Proteins; Tetradecanoylphorbol Acetate | 1995 |
Chronic granulomatous disease in two children with recurrent infections: family studies using dihydrorhodamine-based flow cytometry.
Topics: Flow Cytometry; Fluorescent Dyes; Genetic Carrier Screening; Genetic Linkage; Granulomatous Disease, Chronic; Humans; Infant; Male; Neutrophils; Tetradecanoylphorbol Acetate; X Chromosome | 1997 |
An in-frame triplet deletion within the gp91-phox gene in an adult X-linked chronic granulomatous disease patient with residual NADPH-oxidase activity.
Topics: Adult; Amino Acid Sequence; Antibodies; Bacterial Infections; Cytochrome b Group; Exons; Fatal Outcome; Female; Genetic Carrier Screening; Granulocytes; Granulomatous Disease, Chronic; Heme; Humans; Male; Membrane Glycoproteins; Models, Structural; Molecular Sequence Data; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidase 2; NADPH Oxidases; Neutrophils; Pedigree; Peptide Fragments; Polymorphism, Genetic; Protein Conformation; Sequence Deletion; Superoxides; Tetradecanoylphorbol Acetate; X Chromosome; Zymosan | 1997 |
Regulation of capacitative Ca2+ influx in human neutrophil granulocytes. Alterations in chronic granulomatous disease.
Topics: Calcium; Granulomatous Disease, Chronic; Humans; Ion Transport; Manganese; Membrane Potentials; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate | 1997 |
Diagnosis and carrier detection of chronic granulomatous disease in five families by flow cytometry.
Topics: Adolescent; Adult; Amino Acid Sequence; Child; Female; Flow Cytometry; Granulomatous Disease, Chronic; Heterozygote; Humans; Male; Membrane Transport Proteins; Molecular Sequence Data; NADPH Dehydrogenase; NADPH Oxidases; Neutrophil Activation; Neutrophils; Nitroblue Tetrazolium; Pedigree; Phosphoproteins; Respiratory Burst; Tetradecanoylphorbol Acetate | 1997 |
Confocal Raman microspectroscopy of the activation of single neutrophilic granulocytes.
Topics: Granulomatous Disease, Chronic; Humans; In Vitro Techniques; Macrophage Activation; Microscopy, Confocal; NADPH Oxidases; Neutrophils; Peroxidase; Spectrum Analysis, Raman; Tetradecanoylphorbol Acetate | 1998 |
Nicotinamide-adenine dinucleotide phosphate oxidase assembly and activation in EBV-transformed B lymphoblastoid cell lines of normal and chronic granulomatous disease patients.
Topics: B-Lymphocytes; Biological Transport; Cell Line, Transformed; Cell Membrane; Cytochrome b Group; Enzyme Activation; Granulomatous Disease, Chronic; Herpesvirus 4, Human; Humans; Macromolecular Substances; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mutation; NADPH Dehydrogenase; NADPH Oxidase 2; NADPH Oxidases; Neutrophils; Phosphoproteins; Protein Conformation; Respiratory Burst; Structure-Activity Relationship; Superoxides; Tetradecanoylphorbol Acetate; X Chromosome | 1998 |
Involvement of caspases in neutrophil apoptosis: regulation by reactive oxygen species.
Topics: Apoptosis; Caspases; Cell Size; DNA Fragmentation; Enzyme Activation; fas Receptor; Granulomatous Disease, Chronic; Humans; NADPH Oxidases; Neutrophils; Phosphatidylserines; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Time Factors | 1998 |
Four novel mutations in the gene encoding gp91-phox of human NADPH oxidase: consequences for oxidase assembly.
Topics: Amino Acid Sequence; Amino Acid Substitution; Cell-Free System; Child, Preschool; Cytosol; Granulomatous Disease, Chronic; Humans; In Vitro Techniques; Infant; Leukocytes, Mononuclear; Membrane Glycoproteins; Models, Molecular; Molecular Sequence Data; NADPH Oxidase 2; NADPH Oxidases; Neutrophils; Point Mutation; Protein Structure, Secondary; Reference Values; Respiratory Burst; Sequence Alignment; Sequence Homology, Amino Acid; Superoxides; Tetradecanoylphorbol Acetate | 2000 |
Point mutations in the promoter region of the CYBB gene leading to mild chronic granulomatous disease.
Topics: Adolescent; Adult; Antigens, CD; Child, Preschool; Cytochrome b Group; Eosinophils; Female; Granulocytes; Granulomatous Disease, Chronic; Humans; Male; Membrane Glycoproteins; NADPH Oxidase 2; NADPH Oxidases; Oxidation-Reduction; Oxygen Consumption; Pedigree; Point Mutation; Promoter Regions, Genetic; Rhodamines; Tetradecanoylphorbol Acetate; Tetraspanin 29; Zymosan | 2000 |
Genetic demonstration of p47phox-dependent superoxide anion production in murine vascular smooth muscle cells.
Topics: Actins; Angiotensin II; Animals; Aorta; Becaplermin; Cells, Cultured; Female; Fluorescent Antibody Technique, Indirect; Genes, Reporter; Granulomatous Disease, Chronic; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Phase-Contrast; Muscle, Smooth, Vascular; NADPH Oxidases; Phosphoproteins; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Recombinant Proteins; Retroviridae; Superoxides; Tetradecanoylphorbol Acetate; Transduction, Genetic | 2001 |
The gp91phox component of NADPH oxidase is not the voltage-gated proton channel in phagocytes, but it helps.
Topics: Carcinogens; Cell Line; Electrophysiology; Granulomatous Disease, Chronic; Humans; Hydrogen; Ions; Kinetics; Membrane Glycoproteins; Mutation; NADPH Oxidase 2; NADPH Oxidases; Phagocytes; Protons; Respiratory Burst; Tetradecanoylphorbol Acetate; Transgenes | 2001 |
Molecular and functional characterization of a new X-linked chronic granulomatous disease variant (X91+) case with a double missense mutation in the cytosolic gp91phox C-terminal tail.
Topics: Cell Membrane; Cytochrome b Group; Cytosol; Flavin-Adenine Dinucleotide; Granulomatous Disease, Chronic; Humans; Infant; Male; Membrane Glycoproteins; Mutation, Missense; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidase 2; NADPH Oxidases; Neutrophils; Polymorphism, Single-Stranded Conformational; RNA, Messenger; Tetradecanoylphorbol Acetate | 2002 |
Quantitation of superoxide production in human polymorphonuclear leukocytes from normals and 3 types of chronic granulomatous disease.
Topics: Cytochromes; Female; Granulomatous Disease, Chronic; Humans; Kinetics; Male; Neutrophils; Oxygen; Superoxides; Tetradecanoylphorbol Acetate | 1979 |
An improved nitroblue tetrazolium test using phorbol myristate acetate-coated coverslips.
Topics: Chemical Phenomena; Chemistry; Granulomatous Disease, Chronic; Heterozygote; Humans; Neutrophils; Nitroblue Tetrazolium; Phorbols; Tetradecanoylphorbol Acetate; Tetrazolium Salts | 1979 |
Spectrum of function of neutrophils from carriers of sex-linked chronic granulomatous disease.
Topics: Blood Bactericidal Activity; Blood Glucose; Female; Granulomatous Disease, Chronic; Humans; Male; Neutrophils; Nitroblue Tetrazolium; Oxygen Consumption; Phagocyte Bactericidal Dysfunction; Sex Chromosomes; Tetradecanoylphorbol Acetate | 1975 |
Viricidal effect of stimulated human mononuclear phagocytes on human immunodeficiency virus type 1.
Topics: Azides; Catalase; Cell Line; Cells, Cultured; Granulomatous Disease, Chronic; HIV-1; Humans; Monocytes; Peroxidase; Phagocytosis; Reference Values; Superoxide Dismutase; Tetradecanoylphorbol Acetate | 1992 |
A novel post-translational incorporation of tyrosine into multiple proteins in activated human neutrophils. Correlation with phagocytosis and activation of the NADPH oxidase-mediated respiratory burst.
Topics: Blood Proteins; Cells, Cultured; Edetic Acid; Free Radical Scavengers; Granulomatous Disease, Chronic; Humans; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Peroxidase; Phagocytosis; Phagosomes; Protein Processing, Post-Translational; Respiratory Burst; Tetradecanoylphorbol Acetate; Tyrosine | 1992 |
Neutrophil function screening in patients with chronic granulomatous disease by a flow cytometric method.
Topics: Adult; Coloring Agents; Flow Cytometry; Fluoresceins; Genes, Recessive; Granulomatous Disease, Chronic; Heterozygote; Hexoses; Humans; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Nitroblue Tetrazolium; Oxidation-Reduction; Pentose Phosphate Pathway; Respiratory Burst; Tetradecanoylphorbol Acetate; X Chromosome | 1992 |
Auranofin inhibits the activation pathways of polymorphonuclear leukocytes at multiple sites.
Topics: Auranofin; Cell Survival; Concanavalin A; Deoxyglucose; Granulomatous Disease, Chronic; Humans; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Oxygen; Pentose Phosphate Pathway; Signal Transduction; Stimulation, Chemical; Superoxides; Tetradecanoylphorbol Acetate | 1991 |
Neutrophils from chronic granulomatous disease fail to increase endothelial permeability.
Topics: Adult; Capillary Permeability; Cell Adhesion; Endothelium, Vascular; Granulomatous Disease, Chronic; Humans; Male; Neutrophils; Oxygen; Pancreatic Elastase; Peroxidase; Reference Values; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1991 |
Point mutation in the cytoplasmic domain of the neutrophil p22-phox cytochrome b subunit is associated with a nonfunctional NADPH oxidase and chronic granulomatous disease.
Topics: Adult; Alleles; Amino Acid Sequence; Base Sequence; Cell Membrane; Cloning, Molecular; Cytochrome b Group; Cytosol; DNA; Female; Granulomatous Disease, Chronic; Humans; Kinetics; Macromolecular Substances; Molecular Sequence Data; Mutation; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Tetradecanoylphorbol Acetate | 1991 |
Kinetics of transfused neutrophils in peripheral blood and BAL fluid of a patient with variant X-linked chronic granulomatous disease.
Topics: Blood Transfusion; Bronchoalveolar Lavage Fluid; Child, Preschool; Female; Granulomatous Disease, Chronic; Humans; In Vitro Techniques; Kinetics; Male; Neutrophils; Reference Values; Respiratory Burst; Tetradecanoylphorbol Acetate; Time Factors; X Chromosome | 1991 |
Human eosinophils are more toxic than neutrophils in antibody-independent killing.
Topics: Antibody-Dependent Cell Cytotoxicity; Child; Child, Preschool; Eosinophils; Granulocyte-Macrophage Colony-Stimulating Factor; Granulocytes; Granulomatous Disease, Chronic; Humans; Infant; Killer Cells, Natural; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
Regulation of macrophage function by interferon-gamma. Somatic cell genetic approaches in murine macrophage cell lines to mechanisms of growth inhibition, the oxidative burst, and expression of the chronic granulomatous disease gene.
Topics: Animals; Cell Line; Gene Expression; Granulomatous Disease, Chronic; Interferon-gamma; Macrophages; Mice; Mutation; Oxidation-Reduction; Superoxides; Tetradecanoylphorbol Acetate; X Chromosome | 1990 |
The p67-phox cytosolic peptide of the respiratory burst oxidase from human neutrophils. Functional aspects.
Topics: Blood Proteins; Cytosol; Enzyme Activation; Granulomatous Disease, Chronic; Humans; Kinetics; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Phosphorylation; Reference Values; Superoxides; Tetradecanoylphorbol Acetate | 1990 |
Uncoupling of oxidative and non-oxidative mechanisms in human granulocyte-mediated cytotoxicity: use of cytoplasts and cells from chronic granulomatous disease patient.
Topics: Antibody-Dependent Cell Cytotoxicity; Cell Degranulation; Cytotoxicity, Immunologic; Erythrocytes; Granulomatous Disease, Chronic; Humans; Neutrophils; Oxygen; Superoxides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Phosphorylation of neutrophil 47-kDa cytosolic oxidase factor. Translocation to membrane is associated with distinct phosphorylation events.
Topics: Autoradiography; Biological Transport; Cell Membrane; Cytochrome b Group; Cytosol; Electrophoresis, Gel, Two-Dimensional; Granulomatous Disease, Chronic; Humans; Immunoblotting; Immunosorbent Techniques; Kinetics; Molecular Weight; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Phagocytosis; Phosphoproteins; Phosphorylation; Tetradecanoylphorbol Acetate | 1990 |
Difference in changes of membrane fluidity of polymorphonuclear leukocytes stimulated with phorbol myristate acetate and formyl-methionyl-leucyl-phenylalanine: role of excited oxygen species.
Topics: Adult; Cell Membrane; Granulomatous Disease, Chronic; Humans; Membrane Fluidity; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1990 |
A fast and easy method to determine the production of reactive oxygen intermediates by human and murine phagocytes using dihydrorhodamine 123.
Topics: Animals; Granulomatous Disease, Chronic; Humans; Mice; Oxygen; Phagocytes; Rhodamines; Tetradecanoylphorbol Acetate; Xanthenes; Zymosan | 1990 |
Staining of eosinophils with nitroblue tetrazolium in patients with chronic granulomatous disease.
Topics: Adolescent; Adult; Child; Child, Preschool; Cytochrome b Group; Eosinophils; Female; Flavin-Adenine Dinucleotide; Granulomatous Disease, Chronic; Humans; In Vitro Techniques; Male; Nitroblue Tetrazolium; Staining and Labeling; Tetradecanoylphorbol Acetate; Tetrazolium Salts | 1986 |
Leukotriene B4 metabolism in neutrophils of patients with chronic granulomatous disease: phorbol myristate acetate decreases endogenous leukotriene B4 via NADPH oxidase-dependent mechanism.
Topics: Arachidonate 5-Lipoxygenase; Arachidonic Acid; Arachidonic Acids; Calcimycin; Calcium; Granulomatous Disease, Chronic; Humans; Hydroxyeicosatetraenoic Acids; Kinetics; Leukotriene B4; Male; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; SRS-A; Superoxides; Tetradecanoylphorbol Acetate | 1989 |
Enhancement of normal neutrophil chemiluminescence by chronic granulomatous disease neutrophils.
Topics: Acridines; Adolescent; Child; Female; Granulomatous Disease, Chronic; Humans; Luminescent Measurements; Luminol; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Reference Values; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Wheat Germ Agglutinins | 1989 |
Evaluation of human monocyte oxidative metabolism utilizing a flow cytometric assay.
Topics: Flow Cytometry; Fluoresceins; Granulomatous Disease, Chronic; Humans; Immunoglobulin G; Leukocytes, Mononuclear; Monocytes; Oxygen Consumption; Tetradecanoylphorbol Acetate | 1989 |
Recombinant interferon gamma augments phagocyte superoxide production and X-chronic granulomatous disease gene expression in X-linked variant chronic granulomatous disease.
Topics: Cytochrome b Group; Gene Expression Regulation; Granulocytes; Granulomatous Disease, Chronic; Humans; Interferon-gamma; Kinetics; Macrophages; NADH, NADPH Oxidoreductases; NADPH Oxidases; Nitroblue Tetrazolium; Oxygen Consumption; Phagocytes; Photosystem II Protein Complex; Recombinant Proteins; Superoxides; Tetradecanoylphorbol Acetate | 1987 |
Immunosuppression by activated human neutrophils. Dependence on the myeloperoxidase system.
Topics: Cell Survival; Chlorides; Cytotoxicity, Immunologic; DNA Replication; Glucose Oxidase; Granulomatous Disease, Chronic; Humans; Hydrogen Peroxide; Immune Tolerance; Leukocytes, Mononuclear; Neutrophils; Oxygen; Peroxidase; Tetradecanoylphorbol Acetate | 1987 |
Neutrophil-mediated nonoxidative tumor lysis stimulated by high concentrations of phorbol myristate acetate.
Topics: Anaerobiosis; Animals; Catalase; Cattle; Cell Membrane Permeability; Cell Survival; Dose-Response Relationship, Drug; Exocytosis; Granulomatous Disease, Chronic; Hydrogen Peroxide; Immunotherapy; In Vitro Techniques; Neoplasms, Experimental; Neutrophils; Peroxidase; Superoxide Dismutase; Tetradecanoylphorbol Acetate | 1988 |
Phosphorylation of the subunits of cytochrome b-245 upon triggering of the respiratory burst of human neutrophils and macrophages.
Topics: Adolescent; Adult; Cells, Cultured; Cytochrome b Group; Electrophoresis, Polyacrylamide Gel; Female; Granulomatous Disease, Chronic; Humans; Macrophages; Male; Neutrophils; Oxygen Consumption; Phagocytosis; Phosphorylation; Superoxides; Tetradecanoylphorbol Acetate | 1988 |
Antenatal diagnosis of chronic granulomatous disease.
Topics: Female; Fetal Diseases; Granulomatous Disease, Chronic; Humans; Male; Pregnancy; Prenatal Diagnosis; Tetradecanoylphorbol Acetate; Tetrazolium Salts | 1986 |
Modulation of neutrophil-reduced pyridine nucleotide content following stimulation with phorbol myristate acetate and chemotactic factors.
Topics: Complement C5; Complement C5a; Cytochalasin B; Dose-Response Relationship, Drug; Granulomatous Disease, Chronic; Humans; N-Formylmethionine Leucyl-Phenylalanine; NADP; Neutrophils; Oxidation-Reduction; Superoxides; Tetradecanoylphorbol Acetate | 1985 |
O-phenylenediamine oxidation by phorbol myristate acetate-stimulated human polymorphonuclear leukocytes: characterization of two distinct oxidative mechanisms.
Topics: Azides; Catalase; Cytochrome c Group; Granulomatous Disease, Chronic; Humans; Neutrophils; Oxidation-Reduction; Phenylenediamines; Potassium Cyanide; Sodium Azide; Superoxide Dismutase; Tetradecanoylphorbol Acetate | 1987 |
A possible role for protein phosphorylation in the activation of the respiratory burst in human neutrophils. Evidence from studies with cells from patients with chronic granulomatous disease.
Topics: Arachidonic Acid; Arachidonic Acids; Cell Fractionation; Cell Membrane; Cytoplasmic Granules; Cytosol; Enzyme Activation; Granulomatous Disease, Chronic; Humans; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Phosphoproteins; Phosphorylation; Tetradecanoylphorbol Acetate | 1986 |
N,N'-dimethylthiourea dioxide formation from N,N'-dimethylthiourea reflects hydrogen peroxide concentrations in simple biological systems.
Topics: Animals; Chromatography, Gas; Chromatography, High Pressure Liquid; Edema; Granulomatous Disease, Chronic; Humans; Hydrogen Peroxide; Kinetics; Lung; Neutrophils; Tetradecanoylphorbol Acetate; Thiourea | 1988 |
Evidence for distinct intracellular pools of receptors for C3b and C3bi in human neutrophils.
Topics: Acetone; Antibodies, Monoclonal; Binding Sites, Antibody; Cell Compartmentation; Complement C3b Inactivator Proteins; Cytoplasmic Granules; Fluorescent Antibody Technique; Granulomatous Disease, Chronic; Humans; Molecular Weight; Neutrophils; Organoids; Precipitin Tests; Receptors, Complement; Receptors, Complement 3b; Subcellular Fractions; Tetradecanoylphorbol Acetate | 1985 |
Phorbol myristate acetate induced oxidation of 2',7'-dichlorofluorescin by neutrophils from patients with chronic granulomatous disease.
Topics: Cell Line; Flow Cytometry; Fluoresceins; Granulomatous Disease, Chronic; Heterozygote; Humans; Hydrogen Peroxide; In Vitro Techniques; Monocytes; Neutrophils; Oxidation-Reduction; Tetradecanoylphorbol Acetate | 1988 |
Detection of carriers of the autosomal form of chronic granulomatous disease.
Topics: Genetic Carrier Screening; Granulomatous Disease, Chronic; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidation-Reduction; Oxygen Consumption; Tetradecanoylphorbol Acetate; Zymosan | 1988 |
Purified protein kinase C phosphorylates a 47-kDa protein in control neutrophil cytoplasts but not in neutrophil cytoplasts from patients with the autosomal form of chronic granulomatous disease.
Topics: Chromosome Aberrations; Chromosome Disorders; Electrophoresis, Polyacrylamide Gel; Granulomatous Disease, Chronic; Humans; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Oxygen Consumption; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate; Zymosan | 1988 |
Relationship of protein phosphorylation to the activation of the respiratory burst in human neutrophils. Defects in the phosphorylation of a group of closely related 48-kDa proteins in two forms of chronic granulomatous disease.
Topics: Blood Proteins; Granulomatous Disease, Chronic; Humans; In Vitro Techniques; Kinetics; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Phosphorus Radioisotopes; Phosphorylation; Tetradecanoylphorbol Acetate | 1988 |
Effect of degranulation on superoxide dismutase activity in human neutrophils.
Topics: Cytochalasin B; Cytoplasmic Granules; Granulomatous Disease, Chronic; Humans; Neutrophils; Superoxide Dismutase; Tetradecanoylphorbol Acetate | 1986 |
Quantitative assessment of neutrophil function by flow cytometry.
Topics: Flow Cytometry; Fluoresceins; Granulomatous Disease, Chronic; Humans; Membrane Potentials; Neutrophils; Oxygen; Tetradecanoylphorbol Acetate | 1987 |
Cytochrome b and FAD content in polymorphonuclear leucocytes in a family with X-linked chronic granulomatous disease.
Topics: Adult; Child; Cytochrome b Group; Female; Flavin-Adenine Dinucleotide; Genetic Linkage; Granulomatous Disease, Chronic; Humans; Infant; Male; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Nitroblue Tetrazolium; Oxidation-Reduction; Tetradecanoylphorbol Acetate; X Chromosome | 1986 |
A quantitative assay of oxidative metabolism by neutrophils in whole blood using flow cytometry.
Topics: Adult; Female; Flow Cytometry; Fluoresceins; Fluorescent Dyes; Granulomatous Disease, Chronic; Humans; Hydrogen Peroxide; Lymphocyte Activation; Male; Neutrophils; Oxygen; Tetradecanoylphorbol Acetate | 1985 |