tetradecanoylphorbol acetate has been researched along with Glioma in 137 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 25 (18.25) | 18.7374 |
| 1990's | 78 (56.93) | 18.2507 |
| 2000's | 29 (21.17) | 29.6817 |
| 2010's | 5 (3.65) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, X; Wang, D; Zhang, R | 1 |
| Tseng, CL; Wei, JW | 1 |
| Cui, MN; Kim, HY; Lee, JH; Lee, YD; Oh, IH; Yoon, HH | 1 |
| Abdin, JM; Dohi, T; Kitayama, T; Morioka, N; Morita, K; Nakata, Y | 1 |
| Eling, TE; Kamitani, H; Taniura, S; Watanabe, T | 1 |
| McBean, GJ; Murphy, A; Vines, A | 1 |
| Ali-Osman, F; Okamura, T; Singh, S | 1 |
| Baker, SJ; Ellison, DW; Endersby, R; Hay, N; Zhu, X | 1 |
| De Strooper, B; Iwatsubo, T; Kawano, Y; Murakami, D; Nagano, O; Okamoto, I; Saya, H; Tomita, T; Yumoto, E | 1 |
| Dinh, DH; Foster, DC; Gujrati, M; Kisiel, W; Konduri, SD; Olivero, WC; Rao, JS; Yanamandra, N | 1 |
| Bannerman, PG; González, MI; Robinson, MB | 1 |
| Chen, CT; Gillespie, GY; Goldman, CK; Hong, TM; Teng, LJ; Tsai, JC | 1 |
| Chen, TJ; Chen, YC; Chien, LL; Lin, HY; Shen, SC | 1 |
| Ding, JH; He, HR; Hu, G; Yao, HH | 1 |
| Sutherland, ML; Zhou, J | 1 |
| Hao, XS; Li, Q; Sun, BC; Xu, T | 1 |
| Chen, YC; Chien, LL; Lee, HM; Lin, CW; Shen, SC | 1 |
| Fujioka, A; Shigeyoshi, Y; Takashima, N | 1 |
| Kwon, MS; Lee, JY; Seo, YJ; Shim, EJ; Suh, HW | 1 |
| Morita, K | 1 |
| Ahn, BH; Lee, YH; Min, do S; Park, MH | 1 |
| Benos, DJ; Sapirstein, VS | 1 |
| Brostrom, CO; Brostrom, MA; Brotman, LA; Geller, HM; Lee, C; Wolff, DJ | 1 |
| Chang, J; Chen, CC; Lin, WW | 1 |
| Chorváth, B; Duraj, J; Grófová, M; Hunáková, L; Sedlák, J | 1 |
| Malbon, CC; Strassheim, D | 1 |
| Kaba, K; Matsumoto, T; Miyaji, K; Tani, E; Yamaura, I | 1 |
| Chakravarthy, BR; Isaacs, RJ; Morley, P; Whitfield, JF | 1 |
| Barańska, J; Chaban, V; Czarny, M; Sabała, P | 1 |
| Cox, AJ; Lee, RK; Nitsch, RM; Wurtman, RJ | 1 |
| Huang, D; Jungmann, RA | 1 |
| Chang, J; Chen, CC; Cheng, CS; Huang, HC | 1 |
| Huang, YM; Tang, SJ; Wang, FF | 1 |
| Chorváth, B; Grófová, M; Hunáková, L; Sedlák, J | 1 |
| Byers, DM; Cook, HW; Palmer, FB; Ridgway, ND; Rosé, SD | 1 |
| Beckmann, R; Buchner, K; Haller, H; Hucho, F; Lindschau, C | 1 |
| Chen, CC | 2 |
| Efthimiopoulos, S; Felsenstein, KM; Refolo, LM; Robakis, NK; Sambamurti, K | 1 |
| Audette, M; Bouillon, M | 1 |
| Birrell, GB; Griffith, OH; Hedberg, KK; Mobley, PL | 1 |
| Holden, CM; Mallon, BS; Rumsby, MG; Thompson, HJ; Turner, RA | 1 |
| Goto, S; Hasegawa, K; Inaguma, Y; Kato, K | 1 |
| Busciglio, J; Gabuzda, D; Yankner, BA | 1 |
| Fukushima, D; Ishiura, S; Konishi, M; Maruyama, K; Miyamoto, T; Suzuki, K | 1 |
| Brooker, G; Debernardi, MA; Munshi, R | 1 |
| Han, JS; Ren, MF; Shun, XJ; Wang, JF; Yang, HF | 1 |
| Chuang, DM; Lin, WW | 1 |
| Moynagh, PN; O'Neill, LA; Williams, DC | 1 |
| Alling, C; Gustavsson, L; Lundqvist, C; Rodriguez, FD; Simonsson, P | 1 |
| Byers, DM; Cook, HW; Palmer, FB; Spence, MW | 2 |
| Andoh, T; Hara, A; Nozawa, Y; Sakai, N; Yamada, H; Zhang, W | 1 |
| Furuyama, J; Matsumoto, T; Miyazaki, K; Nakano, A; Tani, E | 1 |
| Lin, XH; Nishiyama, A; Stallcup, WB | 1 |
| Asano, T; Hasegawa, K; Inaguma, Y; Ito, H; Kato, K; Kozawa, O | 1 |
| Colangelo, AM; Mocchetti, I; Pani, L | 1 |
| Dowd, LA; Robinson, MB | 1 |
| Dunican, DJ; Griffiths, R; O'Neill, LA; Williams, DC | 1 |
| Byers, DM; Cook, HW; Morash, SC; Sproull, SA | 1 |
| Hoffman, J; Toews, M; Whittle, S | 1 |
| Chen, CC; Wu, ML | 1 |
| Janik, P; Kowalczyk, D; Maternicka, K; Miłoszewska, J; Szaniawska, B | 1 |
| Heiman, AS; Katz, DI; Tonner, LE | 1 |
| Byers, DM; Cook, HW; Ridgway, ND; Van Iderstine, SC | 1 |
| Feinstein, DL; Militante, JD; Syapin, PJ | 1 |
| Acevedo-Duncan, M; Cooper, DR; Greenberg, HM; Zhang, R | 1 |
| Beale, G; Mallon, B; Morreale, A; Rumsby, M; Watson, J | 1 |
| Ikegaki, N; Ono, Y; Saito, N; Sakai, N; Sasaki, K; Shirai, Y | 1 |
| Banasiak, M; Barańska, J; Czarny, M; Stepkowski, D; Wiktorek-Wójcik, M | 1 |
| Bannerman, PG; Correale, DM; Davis, KE; Robinson, MB; Rothstein, JD; Straff, DJ; Weinstein, EA | 1 |
| Aggarwal, BB; Chintala, SK; Giri, DK; Gokaslan, ZL; Kyritsis, AP; Majumder, S; Rao, JS; Sawaya, R | 1 |
| Henklein, P; Kaufmann, R; Nowak, G; Schafberg, H; Zieger, M | 1 |
| Alvaro, JD; Curran, PK; Duman, RS; Fishman, PH; Fitzgerald, L; Hoffman, G; Hsu, R; Iredale, PA; Li, Z; Machida, CA; Vaidya, VA | 1 |
| Duda, T; Sharma, RK; Venkataraman, V | 1 |
| Barańska, J; Czajkowski, R | 1 |
| Barańska, J; Bobeszko, M; Dygas, A; Sidorko, M | 1 |
| Alvarez-Dolado, M; García-Fernández, LF; González-Sancho, JM; Muñoz, A; Navarro-Yubero, C | 1 |
| Palmer, TM; Stiles, GL | 1 |
| Aggarwal, BB; Chintala, SK; Gokslan, Z; Kyritsis, AP; Mohan, PM; Mohanam, S; Rao, JS; Sawaya, R; Steck, P; Uhm, JH; Yung, WK | 1 |
| Ishikawa, K; Okajima, F; Sato, K; Ui, M | 1 |
| Désy, M; Devaux, C; Franco, E; Gaboury, L; Mandeville, R; Mercier, G; Paris-Nadon, L; Rocheleau, N; Sidrac-Ghali, S | 1 |
| Höllt, V; Kraus, J; Wöltje, M | 1 |
| Besson, A; Yong, VW | 1 |
| Barańska, J; Bobeszko, M; Dygas, A; Nalepa, I | 1 |
| Kuroda, Y; Satoh, J | 1 |
| Bhattacharya, A; Boyd, D; Lakka, SS; Mohanam, S; Rao, JS | 1 |
| Hashimoto, M; Hsu, L; Mallory, M; Masliah, E; Rockenstein, E | 1 |
| Goppelt-Struebe, M; Lanz, S; Ramer, R; Schaefer, D; Schneider, N | 1 |
| Fishman, PH; Leavitt, M; Setola, V | 1 |
| Inaguma, Y; Ito, H; Iwamoto, I; Kato, K; Lida, K | 1 |
| Besson, A; Davy, A; Robbins, SM; Yong, VW | 1 |
| Dinh, DH; Foster, DC; Gujrati, M; Kisiel, W; Konduri, SD; Kouraklis, G; Olivero, WC; Osman, FA; Rao, CN; Rao, JS; Srinivas, H; Tasiou, A; Yanamandra, N | 1 |
| Costa, S; Fages, C; Monville, C; Paillaud, E; Plassat, JL; Rochette-Egly, C; Tardy, M | 1 |
| Howells, RD; Yin, J | 1 |
| Casey, G; Gubits, RM; Munell, F; Vitek, MP; Yu, H | 1 |
| Fields, AP; Goldthwait, DA; Misra-Press, A; Samols, D | 1 |
| Arneson-Rotert, LJ; Hoffman, JM; Liewer, SA; Toews, ML | 1 |
| Bressler, JP; Brightman, MW; Tao-Cheng, JH | 1 |
| Apodaca, G; Banda, MJ; Herron, GS; Howard, EW | 1 |
| Bhat, NR; Fanti, P; Klein, J; Rush, JS; Waechter, CJ | 1 |
| Janik, P; Kowalczyk, D; Miloszewska, J; Pietruszewska, E; Szaniawska, B | 1 |
| Gershengorn, MC; Perlman, JH | 1 |
| Carroll, JM; Goodman, HM; Joh, TH; Kim, KS; Kim, KT | 1 |
| Antel, JP; Couldwell, WT; Uhm, JH; Yong, VW | 1 |
| Gao, XH; Habu, S; Nakamura, Y; Nishimura, T; Okumura, K; Takeuchi, Y; Tokuda, Y | 1 |
| Koeffler, HP; Ross, HJ; Sato, N; Ueyama, Y | 1 |
| Chan, J; Greenberg, DA | 1 |
| Bass, ES; Law, PY; Loh, HH; Louie, AK; Zhan, J | 1 |
| Koschel, K; Tas, PW | 1 |
| Benveniste, EN; Bethea, JR; Chung, IY; Gillespie, GY | 1 |
| Koide, Y; Nezu, N; Ryu, K; Yoshida, TO | 1 |
| Hadi, A; Lotan, R; Steck, PA; Yung, WK | 1 |
| Alterman, RL; Kornblith, PL; Maleci, A; Moskal, JR; Sundstrom, D | 1 |
| Chang, CC; Lin, ZX; Trosko, JE | 1 |
| Imaizumi, T; Mizushima, A; Osugi, T; Uchida, S; Yoshida, H | 2 |
| Bolanowski, MA; Bouvier, M; Caron, MG; Collins, S; Lefkowitz, RJ | 1 |
| Anderson, WB; Gopalakrishna, R | 1 |
| Labouesse, J; Merle, M; Pianet, I | 1 |
| Garin-Chesa, P; Rettig, WJ | 1 |
| Fu, T; Nozawa, Y; Okano, Y | 1 |
| Fishman, PH; Kassis, S; Patel, J; Zaremba, T | 1 |
| Liscovitch, M | 1 |
| Issinger, OG; Rance, AJ; Thönnes, M | 1 |
| Hauser, G; Leli, U | 1 |
| Fishman, PH; Patel, J; Sullivan, M | 1 |
| Kassis, S; Patel, J | 1 |
| Blumberg, PM; Bressler, JP; Frost, MM; Leach, KL | 1 |
| Higashida, H; Klee, W; Nirenberg, M; Streaty, RA | 1 |
| Ballester, R; Birnbaum, MJ; Makowske, M; Rosen, OM | 1 |
| Kokunai, T; Matsumoto, S; Tamaki, N | 1 |
| Janik, P; Miłoszewska, J; Przybyszewska, M; Szaniawska, B | 1 |
| Parker, PJ; Rodriguez-Pena, A; Rozengurt, E; Stabel, S; Young, S | 1 |
| Blusztajn, JK; Liscovitch, M; Slack, B; Wurtman, RJ | 1 |
| Blusztajn, JK; Freese, A; Liscovitch, M; Wurtman, RJ | 1 |
| Bressler, JP; Kornblith, PL; Weingarten, D | 1 |
137 other study(ies) available for tetradecanoylphorbol acetate and Glioma
| Article | Year |
|---|---|
BAMBI promotes macrophage proliferation and differentiation in gliomas.
Topics: Adult; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Arginase; Brain Neoplasms; Cell Differentiation; Cell Line, Tumor; Cell Movement; Cell Proliferation; Female; Gene Expression Regulation, Neoplastic; Glioma; Humans; Interleukin-10; Interleukin-12; Male; Membrane Proteins; Mice; Middle Aged; Neoplasm Grading; Nitric Oxide Synthase Type II; RAW 264.7 Cells; Signal Transduction; Tetradecanoylphorbol Acetate; THP-1 Cells | 2018 |
Homologous desensitization of histamine-mediated signal transduction system in C6 glioma cells.
Topics: Animals; Arachidonic Acid; Brain Neoplasms; Calcium; Cell Line, Tumor; Glioma; Histamine; Inositol Phosphates; Pyrilamine; Rats; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate | 2013 |
Down-modulation of Bis reduces the invasive ability of glioma cells induced by TPA, through NF-κB mediated activation of MMP-9.
Topics: Adaptor Proteins, Signal Transducing; Apoptosis Regulatory Proteins; Cell Line, Tumor; Cell Movement; Down-Regulation; Enzyme Activation; Gene Knockdown Techniques; Glioma; Humans; I-kappa B Proteins; Matrix Metalloproteinase 9; Neoplasm Invasiveness; NF-KappaB Inhibitor alpha; Phosphorylation; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Transcription Factor RelA | 2014 |
The regulation of glycine transporter GLYT1 is mainly mediated by protein kinase Calpha in C6 glioma cells.
Topics: Animals; Astrocytes; Calcium; Carcinogens; Cell Line, Tumor; Diterpenes; Down-Regulation; Enzyme Inhibitors; Glioma; Glycine; Glycine Plasma Membrane Transport Proteins; Isoenzymes; Phorbol Esters; Protein Kinase C-alpha; Protein Kinase C-delta; Protein Kinase C-epsilon; Rats; RNA Interference; Tetradecanoylphorbol Acetate | 2008 |
Induction of cyclooxygenase-2 expression by interleukin-1beta in human glioma cell line, U87MG.
Topics: Astrocytes; Benzo(a)pyrene; Carcinogens; Cell Line, Tumor; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Enzyme Induction; Gene Expression Regulation, Neoplastic; Glioma; Humans; Interferon-gamma; Interleukin-1beta; Neoplasm Proteins; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2008 |
Stimulation of EAAC1 in C6 glioma cells by store-operated calcium influx.
Topics: Animals; Aspartic Acid; Biological Transport; Calcium; Cell Line, Tumor; Excitatory Amino Acid Transporter 3; Extracellular Space; Glioma; Mice; Protein Kinase C; Protein Kinase Inhibitors; Tetradecanoylphorbol Acetate; Thapsigargin | 2009 |
Serine phosphorylation of glutathione S-transferase P1 (GSTP1) by PKCα enhances GSTP1-dependent cisplatin metabolism and resistance in human glioma cells.
Topics: Antineoplastic Agents; bcl-2-Associated X Protein; Cell Line, Tumor; Cisplatin; Drug Resistance, Neoplasm; Glioma; Glutathione S-Transferase pi; Humans; Indoles; Maleimides; Phosphorylation; Protein Kinase C-alpha; Protein Transport; RNA, Small Interfering; Serine; Tetradecanoylphorbol Acetate | 2010 |
Nonredundant functions for Akt isoforms in astrocyte growth and gliomagenesis in an orthotopic transplantation model.
Topics: Animals; Astrocytes; Brain; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; ErbB Receptors; Glioma; Humans; Isoenzymes; Mice; Neoplasm Invasiveness; Neoplasm Transplantation; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53 | 2011 |
Presenilin-dependent gamma-secretase activity mediates the intramembranous cleavage of CD44.
Topics: Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Carbamates; Cell Membrane; Central Nervous System Neoplasms; Dipeptides; Embryo, Mammalian; Endopeptidases; Fibroblasts; Glioma; Humans; Hyaluronan Receptors; Leupeptins; Membrane Proteins; Mice; Mice, Knockout; Pepstatins; Presenilin-1; Protease Inhibitors; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2003 |
Physiological and chemical inducers of tissue factor pathway inhibitor-2 in human glioma cells.
Topics: Base Sequence; Cell Cycle; DNA Primers; Gene Expression Regulation; Glioma; Glycoproteins; Humans; Interferon-alpha; Interferon-gamma; Luciferases; Polymerase Chain Reaction; Promoter Regions, Genetic; Recombinant Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription Factors; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 2003 |
Phorbol myristate acetate-dependent interaction of protein kinase Calpha and the neuronal glutamate transporter EAAC1.
Topics: Amino Acid Transport System X-AG; Animals; Brain; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Transporter 3; Glioma; Glutamate Plasma Membrane Transport Proteins; Macromolecular Substances; Neurons; Protein Kinase C; Protein Kinase C-alpha; Rats; Symporters; Synaptosomes; Tetradecanoylphorbol Acetate | 2003 |
Protein kinase C mediates induced secretion of vascular endothelial growth factor by human glioma cells.
Topics: Cell Line, Tumor; Down-Regulation; Enzyme Inhibitors; Epidermal Growth Factor; Genistein; Glioma; Humans; Protein Kinase C; Protein-Tyrosine Kinases; Signal Transduction; Tetradecanoylphorbol Acetate; Tyrphostins; Vascular Endothelial Growth Factor A | 2003 |
Lipopolysaccharide enhancement of 12-o-tetradecanoylphorbol 13-acetate-mediated transformation in rat glioma C6, accompanied by induction of inducible nitric oxide synthase.
Topics: Animals; Carcinogens; Cell Line, Tumor; Cell Survival; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Induction; Enzyme Inhibitors; Flavanones; Gene Expression; Glioma; Lipopolysaccharides; Matrix Metalloproteinase 9; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Quercetin; Rats; Tetradecanoylphorbol Acetate | 2004 |
Inhibitory effects of 1-methyl-4-phenylpyridinium on glutamate uptake into cultured C6 glioma cells.
Topics: 1-Methyl-4-phenylpyridinium; Amino Acid Transport System X-AG; Animals; Apoptosis; Cell Line, Tumor; Cell Survival; Glioma; Glutamic Acid; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate | 2004 |
Glutamate transporter cluster formation in astrocytic processes regulates glutamate uptake activity.
Topics: Actin Cytoskeleton; Actins; Animals; Astrocytes; Brain Neoplasms; Cell Compartmentation; Cell Line, Tumor; Cell Surface Extensions; Excitatory Amino Acid Transporter 2; Glioma; Glutamic Acid; Green Fluorescent Proteins; Mice; Protein Transport; Recombinant Fusion Proteins; Sucrose; Tetradecanoylphorbol Acetate | 2004 |
Role of cytokines in promoting immune escape of FasL-expressing human colon cancer cells.
Topics: Cell Communication; Cell Line, Tumor; Coculture Techniques; Colonic Neoplasms; Cytokines; Cytotoxicity, Immunologic; Fas Ligand Protein; fas Receptor; Glioma; Humans; Immunohistochemistry; Ionomycin; Ionophores; Jurkat Cells; Membrane Glycoproteins; Phytohemagglutinins; T-Lymphocytes; T-Lymphocytes, Regulatory; Tetradecanoylphorbol Acetate | 2005 |
Lipopolysaccharide plus 12-o-tetradecanoylphorbol 13-acetate induction of migration and invasion of glioma cells in vitro and in vivo: Differential inhibitory effects of flavonoids.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Carcinogens; Cell Movement; Cell Transformation, Neoplastic; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Flavanones; Flavonoids; Glioma; Humans; Kaempferols; Lipopolysaccharides; MAP Kinase Signaling System; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Nitric Oxide; Nitric Oxide Synthase; Rats; Tetradecanoylphorbol Acetate | 2006 |
Circadian rhythm generation in a glioma cell line.
Topics: Animals; Cell Cycle Proteins; Cell Line, Tumor; Chlorocebus aethiops; Circadian Rhythm; Colforsin; COS Cells; Dexamethasone; Glioma; Horses; Humans; Ionomycin; Luminescence; Mice; Nuclear Proteins; Period Circadian Proteins; Promoter Regions, Genetic; Rats; Tetradecanoylphorbol Acetate; Transcription Factors; Up-Regulation | 2006 |
The effects of phorbol 12-myristate 13-acetate, cholera toxin, prostaglandin E2 and norepinephrine on inducible nitric oxide synthase activation induced by lipopolysaccharide in C6 cells.
Topics: Animals; Cell Line, Tumor; Cholera Toxin; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Activation; Glioma; Humans; Lipopolysaccharides; Nitric Oxide Synthase Type II; Norepinephrine; Rats; Signal Transduction; Tetradecanoylphorbol Acetate | 2006 |
High salt culture conditions inhibit serum- and NGF- but not PMA-induced Egr-1 gene transcription in rat C6 glioma cells.
Topics: Animals; Cell Culture Techniques; Cell Line, Tumor; Culture Media; Culture Media, Serum-Free; Early Growth Response Protein 1; Glioma; Nerve Growth Factor; Rats; Serum; Sodium Chloride; Tetradecanoylphorbol Acetate; Transcription, Genetic | 2007 |
Phorbol myristate acetate-induced Egr-1 expression is suppressed by phospholipase D isozymes in human glioma cells.
Topics: Cell Line, Tumor; Early Growth Response Protein 1; Genes, Reporter; Glioma; Humans; Isoenzymes; Phosphatidylinositol 3-Kinases; Phospholipase D; Response Elements; Tetradecanoylphorbol Acetate; Transcriptional Activation | 2007 |
Activation of amiloride-sensitive sodium transport in C6 glioma cells.
Topics: Amiloride; Animals; Biological Transport, Active; Bradykinin; Bucladesine; Cell Line; Colchicine; Diglycerides; Epidermal Growth Factor; Glioma; Protons; Pyrazines; Rats; Sodium; Tetradecanoylphorbol Acetate | 1984 |
Alterations of glial tumor cell Ca2+ metabolism and Ca2+-dependent cAMP accumulation by phorbol myristate acetate.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Animals; Biological Transport, Active; Calcium; Cell Line; Cholera Toxin; Cyclic AMP; Glioma; Kinetics; Neoplasms, Experimental; Norepinephrine; Phorbols; Rats; Tetradecanoylphorbol Acetate; Trifluoperazine | 1982 |
Differential expression of protein kinase C isoforms in glial and neuronal cells. Translocation and down-regulation of PKC isoforms in C6 glioma and NG 108-15 hybrid cells: effects of extracellular Ca(2+)-depletion.
Topics: Animals; Biological Transport; Calcium; Down-Regulation; Glioma; Hybrid Cells; Isoenzymes; Neuroglia; Neurons; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Modulation of protectin (CD59 antigen) cell surface expression on human neoplastic cell lines.
Topics: Antigens, CD; Breast Neoplasms; Calcitriol; Carcinoma; CD59 Antigens; Cell Membrane; Cytokines; Down-Regulation; Electrophoresis, Polyacrylamide Gel; Female; Flow Cytometry; Fluorescent Antibody Technique; Glioma; Humans; Leukemia, Myeloid; Leukemia, Promyelocytic, Acute; Membrane Glycoproteins; Ovarian Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured; Up-Regulation | 1993 |
Phosphorylation of Gi alpha 2 attenuates inhibitory adenylyl cyclase in neuroblastoma/glioma hybrid (NG-108-15) cells.
Topics: Adenylyl Cyclases; Enkephalin, Leucine-2-Alanine; Enzyme Activation; Ethers, Cyclic; Glioma; GTP-Binding Proteins; Hybrid Cells; Naphthalenes; Neuroblastoma; Okadaic Acid; Phorbols; Phosphorylation; Polycyclic Compounds; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Effects of protein kinase C modulators on multidrug resistance in human glioma cells.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Down-Regulation; Drug Resistance, Multiple; Glioma; Humans; Immunoblotting; Isoenzymes; Naphthalenes; Phosphorylation; Polycyclic Compounds; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vincristine | 1995 |
Ca2+ x calmodulin prevents myristoylated alanine-rich kinase C substrate protein phosphorylation by protein kinase Cs in C6 rat glioma cells.
Topics: Amino Acid Sequence; Animals; Calcium; Calmodulin; Cattle; Glioma; Intracellular Signaling Peptides and Proteins; Ionomycin; Keratinocytes; Membrane Proteins; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Myristoylated Alanine-Rich C Kinase Substrate; Phosphorylation; Protein Kinase C; Proteins; Rats; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Changes in Ca2+ concentration in phorbol ester and thapsigargin treated glioma C6 cells. The role of protein kinase C in regulation of Ca2+ entry.
Topics: Animals; Biological Transport; Calcium; Calcium-Transporting ATPases; Cytoskeleton; Endoplasmic Reticulum; Glioma; Mice; Neoplasm Proteins; Nerve Tissue Proteins; Protein Kinase C; Signal Transduction; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Tumor Cells, Cultured | 1995 |
Amyloid precursor protein processing is stimulated by metabotropic glutamate receptors.
Topics: Alanine; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Cell Line; Chelating Agents; Cycloleucine; Embryo, Mammalian; Fetus; Glioma; Glutamic Acid; Hippocampus; Humans; Indoles; Kidney; Kinetics; Maleimides; N-Methylaspartate; Neuroblastoma; Neurons; Neurotoxins; PC12 Cells; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Protein Kinase C; Protein Processing, Post-Translational; Pyrimidines; Quinacrine; Quisqualic Acid; Rats; Receptors, Metabotropic Glutamate; Recombinant Proteins; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1995 |
Transcriptional regulation of the lactate dehydrogenase A subunit gene by the phorbol ester 12-O-tetradecanoylphorbol-13-acetate.
Topics: Animals; Base Sequence; Diglycerides; DNA; Genes, Regulator; Glioma; Indoles; L-Lactate Dehydrogenase; Maleimides; Molecular Sequence Data; Promoter Regions, Genetic; Protein Kinase C; Rats; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription, Genetic; Tumor Cells, Cultured | 1995 |
Differential correlation between translocation and down-regulation of conventional and new protein kinase C isozymes in C6 glioma cells.
Topics: Brain Neoplasms; Dose-Response Relationship, Drug; Glioma; Isoenzymes; Protein Kinase C; Tetradecanoylphorbol Acetate; Time Factors; Translocation, Genetic; Tumor Cells, Cultured | 1995 |
Analysis of c-fos expression in the butyrate-induced F-98 glioma cell differentiation.
Topics: Animals; Base Sequence; Butyrates; Butyric Acid; Cell Differentiation; Cell Division; Gene Expression; Genes, fos; Genes, jun; Glial Fibrillary Acidic Protein; Glioma; Plasmids; Promoter Regions, Genetic; Rats; Recombinant Fusion Proteins; Regulatory Sequences, Nucleic Acid; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transcriptional Activation; Transfection; Tumor Cells, Cultured | 1995 |
Modulation of cell surface EGF receptor and HLA expression on glioma cell lines induced with cytokines and differentiation promoters.
Topics: Antigens, Surface; Cell Differentiation; Cytokines; ErbB Receptors; Glioma; HLA Antigens; Humans; Interferon-gamma; Interleukin-1; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1994 |
Differential expression of MARCKS and other calmodulin-binding protein kinase C substrates in cultured neuroblastoma and glioma cells.
Topics: Amino Acid Sequence; Animals; Calmodulin; GAP-43 Protein; Gene Expression; Glioma; Hot Temperature; Humans; Intracellular Signaling Peptides and Proteins; Membrane Glycoproteins; Membrane Proteins; Mice; Molecular Sequence Data; Myristic Acid; Myristic Acids; Myristoylated Alanine-Rich C Kinase Substrate; Nerve Tissue Proteins; Neuroblastoma; Phosphorylation; Protein Kinase C; Proteins; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Differential nuclear localization of protein kinase C isoforms in neuroblastoma x glioma hybrid cells.
Topics: Animals; Cell Differentiation; Cell Nucleolus; Cell Nucleus; Cytoplasm; Fluorescent Antibody Technique; Glioma; Hybrid Cells; Isoenzymes; Neuroblastoma; Nuclear Envelope; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Effects of Ca2+ on the activation of conventional and new PKC isozymes and on TPA and endothelin-1 induced translocations of these isozymes in intact cells.
Topics: Biological Transport; Calcium; Endothelins; Enzyme Activation; Glioma; Ionomycin; Isoenzymes; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Study of the phorbol ester effect on Alzheimer amyloid precursor processing: sequence requirements and involvement of a cholera toxin sensitive protein.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Brain Neoplasms; Cholera Toxin; Cytoplasm; Glioma; GTP-Binding Proteins; Mutagenesis; Nerve Tissue Proteins; Plasmids; Precipitin Tests; Rats; Recombinant Proteins; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Transduction of retinoic acid and gamma-interferon signal for intercellular adhesion molecule-1 expression on human tumor cell lines: evidence for the late-acting involvement of protein kinase C inactivation.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Cell Adhesion Molecules; Enzyme Activation; Glioma; Humans; Intercellular Adhesion Molecule-1; Interferon-gamma; Isoquinolines; Neuroblastoma; Piperazines; Protein Kinase C; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1993 |
Transition metal chelator TPEN counteracts phorbol ester-induced actin cytoskeletal disruption in C6 rat glioma cells without inhibiting activation or translocation of protein kinase C.
Topics: Actins; Animals; Biological Transport; Chelating Agents; Cytoskeleton; Enzyme Activation; Ethylenediamines; Glioma; Metals; Phosphorylation; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Protein kinase C activation of phospholipase D in C6 glioma cells.
Topics: Alkaloids; Animals; Cell Line; Enzyme Activation; Glioma; Indoles; Phorbol Esters; Phospholipase D; Protein Kinase C; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Dissociation as a result of phosphorylation of an aggregated form of the small stress protein, hsp27.
Topics: Arsenates; Cadmium; Cadmium Chloride; Cell Line; Centrifugation, Density Gradient; Chlorides; Cholera Toxin; Electrophoresis, Polyacrylamide Gel; Glioma; Heat-Shock Proteins; Hot Temperature; Humans; Interleukin-1; Phosphates; Phosphorus Radioisotopes; Phosphorylation; Protein Kinases; Protein Tyrosine Phosphatases; Recombinant Proteins; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Inhibition of beta-amyloid production by activation of protein kinase C.
Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Astrocytes; Carcinogens; Cell Line; Cells, Cultured; Cerebral Cortex; Diglycerides; Enzyme Activation; Female; Fetus; Glioma; Humans; Phorbol Esters; Protease Inhibitors; Protein Kinase C; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1993 |
Activation of the secretory pathway leads to a decrease in the intracellular amyloidogenic fragments generated from the amyloid protein precursor.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Amyloid beta-Protein Precursor; Animals; Cell Line; Glioma; Humans; Isoquinolines; Kinetics; Molecular Weight; Peptide Fragments; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Recombinant Proteins; Staurosporine; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1993 |
Ca2+ inhibition of beta-adrenergic receptor- and forskolin-stimulated cAMP accumulation in C6-2B rat glioma cells is independent of protein kinase C.
Topics: Animals; Calcium; Colforsin; Cyclic AMP; Enzyme Activation; Glioma; Hydrolysis; Isoproterenol; Phosphatidylinositols; Protein Kinase C; Rats; Receptors, Adrenergic, beta; Signal Transduction; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Tumor Cells, Cultured | 1993 |
Suppression by [D-Pen2, D-Pen5]enkephalin on cyclic AMP dependent protein kinase-induced, but not protein kinase C-induced increment of intracellular free calcium in NG108-15 cells.
Topics: Analgesics; Animals; Bucladesine; Calcium; Calcium Channels; Colforsin; Depression, Chemical; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Glioma; Hybrid Cells; Intracellular Fluid; Mice; Neuroblastoma; Potassium Chloride; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Rats; Receptors, Opioid, delta; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Agonist-induced desensitization of ATP receptor-mediated phosphoinositide turnover in C6 glioma cells: comparison with the negative-feedback regulation by protein kinase C.
Topics: Adenosine Triphosphate; Animals; Brain Neoplasms; Diacylglycerol Kinase; Feedback; Glioma; Phosphatidylinositols; Phosphotransferases; Protein Kinase C; Receptors, Purinergic; Sodium Fluoride; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Interleukin-1 and phorbol myristate acetate modulate the peripheral-type benzodiazepine receptor in lymphocytes and glial cells.
Topics: Animals; Binding Sites; Cell Line; Down-Regulation; Glioma; Interleukin-1; Lymphocytes; Mice; Neuroglia; Rats; Receptors, GABA-A; Tetradecanoylphorbol Acetate; Thymoma | 1993 |
Protein kinase C alpha, delta, epsilon and zeta in C6 glioma cells. TPA induces translocation and down-regulation of conventional and new PKC isoforms but not atypical PKC zeta.
Topics: Adenosine Triphosphate; Biological Transport; Cell Membrane; Down-Regulation; Endothelins; Enzyme Activation; Glioma; Isoenzymes; Phosphatidylinositols; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Phosphatidylethanol affects inositol 1,4,5-trisphosphate levels in NG108-15 neuroblastoma x glioma hybrid cells.
Topics: Animals; Bradykinin; Dose-Response Relationship, Drug; Ethanol; Glioma; Glycerophospholipids; Hybrid Cells; Inositol 1,4,5-Trisphosphate; Kinetics; Neuroblastoma; Phosphatidic Acids; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors | 1993 |
Dissociation of phosphorylation and translocation of a myristoylated protein kinase C substrate (MARCKS protein) in C6 glioma and N1E-115 neuroblastoma cells.
Topics: Animals; Biological Transport; Calcium; Calmodulin; Cell Membrane; Cytosol; Drug Stability; Glioma; Hot Temperature; Hydrogen-Ion Concentration; Intracellular Signaling Peptides and Proteins; Kinetics; Membrane Proteins; Mice; Myristic Acid; Myristic Acids; Myristoylated Alanine-Rich C Kinase Substrate; Neuroblastoma; Phosphorylation; Protein Kinase C; Proteins; Rats; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Radiosensitization and inhibition of deoxyribonucleic acid repair in rat glioma cells by long-term treatment with 12-O-tetradecanoylphorbol 13-acetate.
Topics: Animals; Brain Neoplasms; Cell Line; Cell Survival; DNA Damage; DNA Repair; DNA, Neoplasm; Glioma; Protein Kinase C; Radiation-Sensitizing Agents; Rats; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1993 |
Expressions of matrilysin and stromelysin in human glioma cells.
Topics: Blotting, Northern; Enzyme Induction; Glioma; Humans; Matrix Metalloproteinase 3; Matrix Metalloproteinase 7; Metalloendopeptidases; Molecular Weight; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transforming Growth Factor beta; Tumor Cells, Cultured | 1993 |
Generation of truncated forms of the NG2 proteoglycan by cell surface proteolysis.
Topics: Animals; Antibodies, Monoclonal; Antigens; Blotting, Northern; Brain Neoplasms; Cell Line; Cell Membrane; Glioma; Humans; Immunoblotting; Kinetics; Methionine; Molecular Weight; Protein Processing, Post-Translational; Proteoglycans; Rats; Recombinant Proteins; RNA, Messenger; Sequence Deletion; Sulfur Radioisotopes; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Trypsin; Tumor Cells, Cultured | 1995 |
Modulation of the stress-induced synthesis of stress proteins by a phorbol ester and okadaic acid.
Topics: Alkaloids; Animals; Arachidonic Acid; Arsenites; Blotting, Northern; Blotting, Western; Enzyme Activation; Ethers, Cyclic; Glioma; Heat-Shock Proteins; Okadaic Acid; Protein Kinase C; Rats; RNA, Messenger; Serine Proteinase Inhibitors; Staurosporine; Stimulation, Chemical; Stress, Physiological; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Correlation between increased AP-1NGF binding activity and induction of nerve growth factor transcription by multiple signal transduction pathways in C6-2B glioma cells.
Topics: Animals; Base Sequence; Cell Line; Cell Nucleus; Enzyme Inhibitors; Fibroblast Growth Factor 2; Glioma; Isoproterenol; Molecular Sequence Data; Nerve Growth Factors; Oligodeoxyribonucleotides; Rats; RNA Processing, Post-Transcriptional; RNA, Messenger; Signal Transduction; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Transcription Factor AP-1; Transcription, Genetic; Tumor Cells, Cultured | 1996 |
Rapid stimulation of EAAC1-mediated Na+-dependent L-glutamate transport activity in C6 glioma cells by phorbol ester.
Topics: Adenylyl Cyclases; Amiloride; Amino Acid Transport System X-AG; Animals; Aspartic Acid; ATP-Binding Cassette Transporters; Calcimycin; Carrier Proteins; Colforsin; Enzyme Inhibitors; Ethers, Cyclic; Excitatory Amino Acid Transporter 3; Glioma; Glutamate Plasma Membrane Transport Proteins; Glutamates; Glycine; Kinetics; Okadaic Acid; Phosphoric Monoester Hydrolases; Protein Kinase C; Rats; Sodium; Sodium-Potassium-Exchanging ATPase; Symporters; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1996 |
Endothelin-1 increases arachidonic acid release in C6 glioma cells through a potassium-modulated influx of calcium.
Topics: Animals; Arachidonic Acid; Calcimycin; Calcium; Endothelins; Enzyme Activation; Glioma; Ion Channel Gating; Ionophores; Phospholipases A; Phospholipases A2; Potassium; Rats; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Valinomycin | 1996 |
Phorbol ester stimulation of phosphatidylcholine synthesis in four cultured neural cell lines: correlations with expression of protein kinase C isoforms.
Topics: Animals; Blotting, Northern; Blotting, Western; Choline; Gene Expression; Glioma; Humans; Isoenzymes; Mice; Neuroblastoma; Oleic Acid; Oleic Acids; Phosphatidylcholines; Protein Kinase C; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Modulation of cyclic AMP accumulation in glial cells by exogenous phospholipase C.
Topics: Adenylate Cyclase Toxin; Astrocytoma; Colforsin; Cyclic AMP; Down-Regulation; Glioma; Humans; Isoproterenol; Lysophospholipids; Neuroglia; Pertussis Toxin; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Type C Phospholipases; Virulence Factors, Bordetella | 1996 |
Protein kinase C isoform delta is involved in the stimulation of the Na(+)-H+ exchanger in C6 glioma cells.
Topics: Dose-Response Relationship, Drug; Down-Regulation; Enzyme Activation; Glioma; Humans; Isoenzymes; Kinetics; Protein Kinase C; Sodium-Hydrogen Exchangers; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Translocation, Genetic; Tumor Cells, Cultured | 1995 |
The pleiotropic effect of TPA on in vitro invasion/migration of glioma and melanoma cell lines.
Topics: Animals; Carcinogens; Cell Movement; Down-Regulation; Glioma; Humans; Isoenzymes; Melanoma; Neoplasm Invasiveness; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1996 |
The acute effect of lead acetate on glucocorticoid receptor binding in C6 glioma cells.
Topics: Animals; Cell Division; Cell Survival; Dexamethasone; Enzyme Activation; Enzyme Induction; Glioma; Glycerolphosphate Dehydrogenase; Kinetics; Organometallic Compounds; Protein Kinase C; Rats; Receptors, Glucocorticoid; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1997 |
Phospholipase D hydrolysis of plasmalogen and diacyl ethanolamine phosphoglycerides by protein kinase C dependent and independent mechanisms.
Topics: Animals; Enzyme Activation; Enzyme Inhibitors; Glioma; Hydrolysis; Kinetics; Phosphatidylethanolamines; Phospholipase D; Plasmalogens; Protein Kinase C; Rats; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1997 |
Suppression by ethanol of inducible nitric oxide synthase expression in C6 glioma cells.
Topics: Animals; Enzyme Inhibitors; Ethanol; Glioma; Lipopolysaccharides; Nitric Oxide Synthase; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1997 |
Effects of interferon and PKC modulators on human glioma protein kinase C, cell proliferation, and cell cycle.
Topics: Antineoplastic Agents; Cell Cycle; Cell Division; Drug Screening Assays, Antitumor; Enzyme Activation; Enzyme Inhibitors; Glioma; Humans; Interferon alpha-2; Interferon-alpha; Naphthalenes; Protein Kinase C; Recombinant Proteins; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1997 |
Ro31-8220 inhibits protein kinase C to block the phorbol ester-stimulated release of choline- and ethanolamine-metabolites from C6 glioma cells: p70 S6 kinase and MAPKAP kinase-1beta do not function downstream of PKC in activating PLD.
Topics: Androstadienes; Animals; Choline; Enzyme Inhibitors; Ethanolamine; Flavonoids; Glioma; Indoles; Phosphoinositide-3 Kinase Inhibitors; Phospholipase D; Polyenes; Protein Kinase C; Protein Serine-Threonine Kinases; Rats; Ribosomal Protein S6 Kinases; Ribosomal Protein S6 Kinases, 90-kDa; Sirolimus; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Wortmannin | 1997 |
Direct visualization of the translocation of the gamma-subspecies of protein kinase C in living cells using fusion proteins with green fluorescent protein.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Calcimycin; Calcium; CHO Cells; COS Cells; Cricetinae; Cytochalasin D; Glioma; Green Fluorescent Proteins; Hybrid Cells; Isoenzymes; Kinetics; Luminescent Proteins; Mice; Microscopy, Confocal; Molecular Sequence Data; Neuroblastoma; Protein Kinase C; Receptors, N-Methyl-D-Aspartate; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Transfection | 1997 |
Serine base exchange enzyme activity is modulated by sphingosine and other amphiphilic compounds: possible role of positive charge in increasing the synthesis of phosphatidylserine.
Topics: Animals; Cholesterol Esters; Glioma; Kinetics; Microsomes; Microsomes, Liver; Nitrogenous Group Transferases; Phosphatidylserines; Phosphorylcholine; Protein Kinase C; Rats; Sphingosine; Tetradecanoylphorbol Acetate; Thapsigargin; Tumor Cells, Cultured | 1997 |
Multiple signaling pathways regulate cell surface expression and activity of the excitatory amino acid carrier 1 subtype of Glu transporter in C6 glioma.
Topics: Amino Acid Transport System X-AG; Androstadienes; Animals; Biological Transport; Carcinogens; Carrier Proteins; Cell Membrane; Enzyme Inhibitors; Glioma; Glutamate Plasma Membrane Transport Proteins; Glutamates; Glycine; Microscopy, Confocal; Phosphatidylinositol 3-Kinases; Protein Kinase C; Signal Transduction; Symporters; Tetradecanoylphorbol Acetate; Tritium; Tumor Cells, Cultured; Wortmannin | 1998 |
Induction of matrix metalloproteinase-9 requires a polymerized actin cytoskeleton in human malignant glioma cells.
Topics: Actins; Biopolymers; Brain Neoplasms; Cell Adhesion Molecules; Collagenases; Cytochalasin D; Cytoskeleton; Enzyme Activation; Enzyme Induction; Enzyme Inhibitors; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Glioma; Humans; Matrix Metalloproteinase 9; Neoplasm Invasiveness; NF-kappa B; Protein Kinase C; Protein-Tyrosine Kinases; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1998 |
Protein kinase C is involved in cholecystokinin octapeptide-induced proliferative action in rat glioma C6 cells.
Topics: Animals; Blotting, Western; Carcinogens; Enzyme Activation; Glioma; Isoenzymes; Protein Kinase C; Protein Kinase C beta; Rats; Signal Transduction; Sincalide; Tetradecanoylphorbol Acetate; Thymidine; Tritium; Tumor Cells, Cultured | 1998 |
Protein kinase C-mediated down-regulation of beta1-adrenergic receptor gene expression in rat C6 glioma cells.
Topics: Animals; Carcinogens; Cyclic AMP; Down-Regulation; Glioma; Promoter Regions, Genetic; Protein Kinase C; Rats; Receptors, Adrenergic, beta-1; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1998 |
alpha2D/A-adrenergic receptor gene induction in the retina by phorbol ester: involvement of an AP-2 element.
Topics: Animals; Cattle; Gene Expression Regulation; Glioma; Promoter Regions, Genetic; Receptors, Adrenergic, alpha-2; Response Elements; Retina; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transcriptional Activation; Tumor Cells, Cultured | 1999 |
Sphingosine and phorbol ester modulate protein kinase C activity and modify ATP-evoked calcium mobilization in glioma C6 cells.
Topics: Adenosine Triphosphate; Animals; Calcium; Calcium Signaling; Endoplasmic Reticulum; Enzyme Activation; Glioma; Indoles; Maleimides; Protein Kinase C; Rats; Sphingosine; Tetradecanoylphorbol Acetate; Thapsigargin; Time Factors; Tumor Cells, Cultured; Type C Phospholipases | 1999 |
Exogenous sphingosine 1-phosphate and sphingosylphosphorylcholine do not stimulate phospholipase D in C6 glioma cells.
Topics: Brain Neoplasms; Enzyme Activation; Glioma; Lysophospholipids; Phospholipase D; Phosphorylcholine; Sphingosine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1999 |
Retinoic acid and 1,25-dihydroxyvitamin D3 inhibit tenascin-C expression in rat glioma C6 cells.
Topics: Animals; Calcitriol; Carcinogens; Drug Synergism; Glioma; Prostaglandin D2; Rats; Receptors, Calcitriol; Tenascin; Tetradecanoylphorbol Acetate; Tretinoin; Up-Regulation | 1999 |
Stimulation of A(2A) adenosine receptor phosphorylation by protein kinase C activation: evidence for regulation by multiple protein kinase C isoforms.
Topics: Acetophenones; Animals; Benzopyrans; Carbazoles; CHO Cells; Consensus Sequence; Cricetinae; Cyclic AMP; Dogs; Endothelin-1; Enzyme Activation; Enzyme Inhibitors; Glioma; Indoles; Isoenzymes; Maleimides; Mutagenesis, Site-Directed; Phosphorylation; Protein Kinase C; Rats; Receptor, Adenosine A2A; Receptors, Purinergic P1; Signal Transduction; Tetradecanoylphorbol Acetate; Triazines; Triazoles; Tumor Cells, Cultured | 1999 |
Altered actin cytoskeleton and inhibition of matrix metalloproteinase expression by vanadate and phenylarsine oxide, inhibitors of phosphotyrosine phosphatases: modulation of migration and invasion of human malignant glioma cells.
Topics: Actins; Arsenicals; Cell Adhesion Molecules; Cell Movement; Cytoskeleton; Enzyme Inhibitors; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Gene Expression Regulation, Neoplastic; Glioma; Humans; Matrix Metalloproteinases; Neoplasm Invasiveness; Phosphoproteins; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vanadates | 1999 |
Sphingosine 1-phosphate induces expression of early growth response-1 and fibroblast growth factor-2 through mechanism involving extracellular signal-regulated kinase in astroglial cells.
Topics: Animals; Animals, Newborn; Astrocytes; Cells, Cultured; DNA-Binding Proteins; Early Growth Response Protein 1; Endothelins; Fibroblast Growth Factor 2; Flavonoids; Gene Expression Regulation; Glioma; GTP-Binding Proteins; Immediate-Early Proteins; Lysophospholipids; Mitogen-Activated Protein Kinases; Naphthalenes; Pertussis Toxin; Platelet-Derived Growth Factor; Protein Kinase C; Rats; RNA, Messenger; Sphingosine; Tetradecanoylphorbol Acetate; Transcription Factors; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1999 |
Evaluation of the potential promoting effect of 60 Hz magnetic fields on N-ethyl-N-nitrosourea induced neurogenic tumors in female F344 rats.
Topics: Animals; Body Weight; Brain Neoplasms; Central Nervous System Neoplasms; Electromagnetic Fields; Ethylnitrosourea; Female; Glioma; Neurilemmoma; Peripheral Nervous System Neoplasms; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred F344; Spinal Cord Neoplasms; Tetradecanoylphorbol Acetate | 2000 |
Regulation of mouse delta-opioid receptor gene transcription: involvement of the transcription factors AP-1 and AP-2.
Topics: 1-Methyl-3-isobutylxanthine; Aged; Animals; Carcinogens; Colforsin; Cyclic AMP-Dependent Protein Kinases; DNA-Binding Proteins; Gene Expression Regulation, Enzymologic; Genetic Complementation Test; Glioma; Humans; Mice; Phosphodiesterase Inhibitors; Promoter Regions, Genetic; Protein Kinase C; Receptor Cross-Talk; Receptors, Opioid, delta; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription Factor AP-2; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured | 2000 |
Involvement of p21(Waf1/Cip1) in protein kinase C alpha-induced cell cycle progression.
Topics: Cell Cycle; Cell Division; Central Nervous System Neoplasms; Cyclin A; Cyclin B; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinases; Cyclins; Enzyme Activation; Glioma; Humans; Isoenzymes; Oligonucleotides, Antisense; Phorbol Esters; Protein Kinase C; Protein Kinase C-delta; Protein Kinase C-epsilon; Protein Kinase C-theta; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Up-Regulation | 2000 |
Different regulation of phospholipase D activity in glioma C6 cells by sphingosine, propranolol, imipramine and phorbol ester.
Topics: Animals; Brain Neoplasms; Cell Compartmentation; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Glioma; Imipramine; Indoles; Isoenzymes; Maleimides; Neoplasm Proteins; Phospholipase D; Propranolol; Protein Kinase C; Rats; Sphingosine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2000 |
Beta-catenin expression in human neural cell lines following exposure to cytokines and growth factors.
Topics: Astrocytoma; beta Catenin; Brain Neoplasms; Bucladesine; Cadherins; Cell Differentiation; Cytokines; Cytoskeletal Proteins; Gene Expression Regulation, Neoplastic; Glioma; Growth Substances; HeLa Cells; HL-60 Cells; Humans; Neuroblastoma; Neurons; Retinal Neoplasms; Retinoblastoma; Tetradecanoylphorbol Acetate; Trans-Activators; Transcription, Genetic; Tumor Cells, Cultured | 2000 |
Regulation of the urokinase-type plasminogen activator receptor gene in different grades of human glioma cell lines.
Topics: beta-Galactosidase; Chloramphenicol O-Acetyltransferase; Dichlororibofuranosylbenzimidazole; Electrophoresis, Agar Gel; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Genes, jun; Glioma; Humans; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Mutation; Promoter Regions, Genetic; Proto-Oncogene Proteins c-raf; Receptors, Cell Surface; Receptors, Urokinase Plasminogen Activator; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Tumor Cells, Cultured; Up-Regulation | 2001 |
Altered expression of glutamate transporters under hypoxic conditions in vitro.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Carrier Proteins; Cell Death; Cell Hypoxia; Excitatory Amino Acid Transporter 2; Excitatory Amino Acid Transporter 3; Gene Expression Regulation; Glioma; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Hypothalamic Neoplasms; Indoles; Maleimides; Mice; Mitochondria; Nerve Tissue Proteins; Neuroglia; Neurons; Protein Kinase C; Rats; Receptors, Neurotransmitter; Recombinant Fusion Proteins; RNA, Messenger; Symporters; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 2001 |
Up-regulation of cyclooxygenase-1 in neuroblastoma cell lines by retinoic acid and corticosteroids.
Topics: Adrenal Cortex Hormones; Aldosterone; Animals; Benzimidazoles; Bucladesine; Calcimycin; Cell Differentiation; Cycloheximide; Cyclooxygenase 1; Cyclooxygenase 2; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dexamethasone; Dinoprostone; Drug Synergism; Enzyme Induction; Estradiol; Gene Expression Regulation, Neoplastic; Genes, Reporter; Glioma; Hybrid Cells; Hydrocortisone; Ionophores; Isoenzymes; Luciferases; Membrane Proteins; Mice; Mifepristone; Neoplasm Proteins; Nerve Tissue Proteins; Neuroblastoma; Promoter Regions, Genetic; Prostaglandin-Endoperoxide Synthases; Protein Synthesis Inhibitors; Receptors, Glucocorticoid; Recombinant Fusion Proteins; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Transfection; Tretinoin; Tumor Cells, Cultured | 2001 |
Protein kinase C-mediated down-regulation of beta(2)-adrenergic receptor and gene expression in rat C6 glioma cells.
Topics: Animals; Blotting, Western; Cyclic AMP; Down-Regulation; Enzyme Activation; Gene Expression; Glioma; Kinetics; Protein Kinase C; Rats; Receptors, Adrenergic, beta-2; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 2001 |
Protein kinase inhibitors can suppress stress-induced dissociation of Hsp27.
Topics: Anisomycin; Arsenites; Butadienes; Cadmium Chloride; Carcinogens; Dithiothreitol; Enzyme Inhibitors; Flavonoids; Glioma; Heat-Shock Proteins; Humans; Hydrogen Peroxide; Imidazoles; MAP Kinase Kinase Kinases; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Nitriles; Osmotic Pressure; Oxidants; p38 Mitogen-Activated Protein Kinases; Protein Kinase C; Protein Synthesis Inhibitors; Pyridines; Sodium Compounds; Sorbitol; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2001 |
Differential activation of ERKs to focal adhesions by PKC epsilon is required for PMA-induced adhesion and migration of human glioma cells.
Topics: Androstadienes; Brain Neoplasms; Butadienes; Cell Adhesion; Cell Movement; Enzyme Activation; Enzyme Inhibitors; Focal Adhesions; Glioma; Humans; Isoenzymes; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Neoplasm Proteins; Nitriles; Phosphorylation; Protein Kinase C; Protein Kinase C-epsilon; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Pyrimidines; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Wortmannin | 2001 |
Minimal and inducible regulation of tissue factor pathway inhibitor-2 in human gliomas.
Topics: Base Sequence; Binding Sites; Brain Neoplasms; Electrophoretic Mobility Shift Assay; Enhancer Elements, Genetic; Gene Expression Regulation, Neoplastic; Genes, Reporter; Glioma; Glycoproteins; Humans; Luciferases; Molecular Sequence Data; Neoplasm Invasiveness; Neoplasm Proteins; Promoter Regions, Genetic; Recombinant Fusion Proteins; Sequence Deletion; Tetradecanoylphorbol Acetate; Transcription Factors; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 2002 |
Retinoic acid increases proliferation rate of GL-15 glioma cells, involving activation of STAT-3 transcription factor.
Topics: Antineoplastic Agents; Apoptosis; Brain Neoplasms; Carcinogens; Cell Division; Cell Nucleus; DNA-Binding Proteins; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Glioma; Humans; Protein Transport; Receptors, Retinoic Acid; RNA, Messenger; STAT3 Transcription Factor; Staurosporine; Tetradecanoylphorbol Acetate; Trans-Activators; Tretinoin; Tumor Cells, Cultured | 2002 |
Glucocorticoid-mediated down regulation of c-fos mRNA in C6 glioma cells: lack of correlation with proenkephalin mRNA.
Topics: Animals; Base Sequence; Brain; Cell Line; Dexamethasone; Enkephalins; Gene Expression Regulation, Neoplastic; Genes, fos; Glioma; Isoproterenol; Kinetics; Molecular Sequence Data; Protein Precursors; Proto-Oncogene Proteins c-fos; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate | 1992 |
Altered genetic response to beta-adrenergic receptor activation in late passage C6 glioma cells.
Topics: Actins; Amyloid beta-Protein Precursor; Animals; Blotting, Northern; Bucladesine; Cell Division; Enkephalins; Gene Expression; Genes, fos; Genes, jun; Glial Fibrillary Acidic Protein; Glioma; Isoproterenol; Kinetics; Nerve Growth Factors; Protein Precursors; Rats; Receptors, Adrenergic, beta; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
Protein kinase C isoforms in human glioblastoma cells.
Topics: Cyclic AMP; Glioma; Half-Life; Humans; Isoenzymes; Neuroglia; Protein Kinase C; Reference Values; RNA, Messenger; Subcellular Fractions; Tetradecanoylphorbol Acetate; Tissue Distribution; Transforming Growth Factor beta; Tumor Cells, Cultured | 1992 |
Serum-induced sensitization of cyclic AMP accumulation in C62B rat glioma cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Blood Physiological Phenomena; Cyclic AMP; Glioma; Isoproterenol; Magnesium; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
Astroglial membrane structure is affected by agents that raise cyclic AMP and by phosphatidylcholine phospholipase C.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Astrocytes; Cattle; Cell Membrane; Cells, Cultured; Colforsin; Cyclic AMP; Freeze Fracturing; Glioma; Guinea Pigs; Immunohistochemistry; Isoproterenol; Lectins; Phosphatidylcholines; Phospholipase D; Protein Kinase C; Protein Kinases; Rats; Retina; Second Messenger Systems; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Type C Phospholipases | 1992 |
Secreted inhibitors of metalloproteinases (IMPs) that are distinct from TIMP.
Topics: Amino Acid Sequence; Animals; Astrocytes; Brain Neoplasms; Cells, Cultured; Culture Media, Conditioned; Electrophoresis, Polyacrylamide Gel; Endothelium, Vascular; Enzyme Induction; Fibroblasts; Glioma; Glycoproteins; Humans; Metalloendopeptidases; Molecular Sequence Data; Molecular Weight; Neoplasm Proteins; Rabbits; Sequence Alignment; Sequence Homology, Amino Acid; Tetradecanoylphorbol Acetate; Tissue Inhibitor of Metalloproteinase-2; Tissue Inhibitor of Metalloproteinases; Tumor Cells, Cultured | 1992 |
Direct assay of membrane-associated protein kinase C activity in B lymphocytes in the presence of Brij 58.
Topics: Adenosine Triphosphate; Animals; B-Lymphocytes; Cell Fractionation; Cell Membrane; Cells, Cultured; Cetomacrogol; Cytosol; Detergents; Female; Glioma; Kinetics; Mice; Mice, Inbred DBA; Osteoblasts; Phosphorus Radioisotopes; Protein Kinase C; Radioisotope Dilution Technique; Rats; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
The role of protein kinase C in migration of rat glioma cells from spheroid cultures.
Topics: Animals; Brain Neoplasms; Cell Division; Cell Line; Cell Movement; Glioma; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
Thyrotropin-releasing hormone stimulation of phosphoinositide hydrolysis desensitizes. Evidence against mediation by protein kinase C or calcium.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium; Cells, Cultured; Chlorides; Dose-Response Relationship, Drug; Drug Tolerance; Glioma; Hydrolysis; Isoquinolines; Lithium; Lithium Chloride; Phosphatidylinositols; Piperazines; Pituitary Gland; Protein Kinase C; Tetradecanoylphorbol Acetate; Thyrotropin-Releasing Hormone | 1991 |
Effects of second messenger system activation on functional expression of tyrosine hydroxylase fusion gene constructs in neuronal and nonneuronal cells.
Topics: Animals; Base Sequence; Blotting, Northern; Cells, Cultured; Chlorocebus aethiops; Colforsin; Cyclic AMP; Dexamethasone; Enzyme Induction; Fibroblasts; Glioma; HeLa Cells; Humans; Mice; Molecular Sequence Data; Neuroblastoma; Neurons; Organ Specificity; Promoter Regions, Genetic; Rats; Recombinant Fusion Proteins; Regulatory Sequences, Nucleic Acid; RNA, Messenger; Second Messenger Systems; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Tumor Cells, Cultured; Tyrosine 3-Monooxygenase | 1991 |
Enhanced protein kinase C activity correlates with the growth rate of malignant gliomas in vitro.
Topics: Alkaloids; Animals; Brain Neoplasms; Cell Division; DNA, Neoplasm; Glioma; Humans; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
Bispecific antibody-directed antitumor activity of human CD4+ helper/killer T cells induced by anti-CD3 monoclonal antibody plus interleukin 2.
Topics: Antibodies, Monoclonal; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Calcimycin; CD3 Complex; CD4 Antigens; Cell Line; Cells, Cultured; Cytotoxicity, Immunologic; DNA Replication; Glioma; Humans; Interleukin-2; Killer Cells, Natural; Kinetics; Lymphocyte Activation; Receptors, Antigen, T-Cell; Recombinant Proteins; T-Lymphocyte Subsets; T-Lymphocytes, Helper-Inducer; Tetradecanoylphorbol Acetate; Thymidine | 1991 |
Cytokine messenger RNA stability is enhanced in tumor cells.
Topics: Adenocarcinoma; Base Sequence; Carcinoma, Hepatocellular; Cell Line; Cytokines; Gene Expression Regulation, Neoplastic; Glioma; Globins; Granulocyte-Macrophage Colony-Stimulating Factor; Kinetics; Liver Neoplasms; Lung Neoplasms; Molecular Sequence Data; Pancreatic Neoplasms; RNA, Messenger; Tetradecanoylphorbol Acetate; Transfection | 1991 |
Endothelin and calcium signaling in NG108-15 neuroblastoma x glioma cells.
Topics: Animals; Calcium; Cell Differentiation; Endothelins; Ethanol; Glioma; Mice; Neuroblastoma; Potassium Chloride; Protein Kinase C; Temperature; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
Attenuation of opioid receptor activity by phorbol esters in neuroblastoma x glioma NG108-15 hybrid cells.
Topics: Adenosine Diphosphate Ribose; Cyclic AMP; Glioma; GTP Phosphohydrolases; GTP-Binding Proteins; Hybrid Cells; Neuroblastoma; Receptors, Adrenergic, alpha; Receptors, Muscarinic; Receptors, Opioid; Tetradecanoylphorbol Acetate | 1990 |
Thrombin reverts the beta-adrenergic agonist-induced morphological response in rat glioma C6 cells.
Topics: Animals; Antithrombin III; Astrocytes; Blood; Calcium; Culture Media; Epithelial Cells; Glioma; Hirudins; Ionomycin; Isoproterenol; Microscopy, Electron, Scanning; Neomycin; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Signal Transduction; Tetradecanoylphorbol Acetate; Thrombin; Tumor Cells, Cultured | 1990 |
Tumor necrosis factor production and receptor expression by a human malignant glioma cell line, D54-MG.
Topics: Cell Division; Glioma; Humans; Interferon-gamma; Lipopolysaccharides; Receptors, Cell Surface; Receptors, Tumor Necrosis Factor; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1990 |
Regulation of HLA class II molecule expressions by IFN-gamma. The signal transduction mechanism in glioblastoma cell lines.
Topics: Biological Transport; Blotting, Northern; Calcimycin; Calcium; Cell Compartmentation; Enzyme Activation; Gene Expression Regulation, Neoplastic; Glioma; HLA-D Antigens; HLA-DP Antigens; HLA-DR Antigens; Humans; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Promoter Regions, Genetic; Protein Kinase C; RNA, Messenger; RNA, Neoplasm; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 1990 |
Inhibition of epidermal growth factor receptor activity by retinoic acid in glioma cells.
Topics: Cell Division; Dose-Response Relationship, Drug; Drug Synergism; ErbB Receptors; Glioma; Glycoconjugates; Humans; Protein Kinase C; Protein-Tyrosine Kinases; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1990 |
Effect of phorbol esters on the susceptibility of a glioma cell line to lymphokine-activated killer cell activity.
Topics: Cell Division; Glioma; Humans; Killer Cells, Lymphokine-Activated; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Kinase C; Tetradecanoylphorbol Acetate; Thymidine; Tumor Cells, Cultured | 1990 |
Gap junctional intercellular communication (GJIC) in rat glioma cells--characterizations to detect inhibitors of metabolic cooperation.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Autoradiography; Brain Neoplasms; Cell Communication; Dieldrin; Glioma; Hypoxanthine Phosphoribosyltransferase; Intercellular Junctions; Rats; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
1-Oleoyl-2-acetyl-glycerol and phorbol diester stimulate Ca2+ influx through Ca2+ channels in neuroblastoma x glioma hybrid NG108-15 cells.
Topics: Calcium; Diglycerides; Glioma; Glycerides; Humans; Hybrid Cells; Ion Channels; Kinetics; Nervous System Neoplasms; Neuroblastoma; Tetradecanoylphorbol Acetate | 1986 |
cAMP stimulates transcription of the beta 2-adrenergic receptor gene in response to short-term agonist exposure.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Base Sequence; Cell Line; Cell Membrane; Colforsin; Cricetinae; Cyclic AMP; Epinephrine; Genes; Glioma; Kinetics; Rats; Receptors, Adrenergic, beta; RNA, Messenger; Tetradecanoylphorbol Acetate; Theophylline; Transcription, Genetic | 1989 |
Ca2+- and phospholipid-independent activation of protein kinase C by selective oxidative modification of the regulatory domain.
Topics: Animals; Brain; Calcium; Cattle; Cell Line; Egtazic Acid; Enzyme Activation; Glioma; Hydrogen Peroxide; Kinetics; Phorbol 12,13-Dibutyrate; Phosphatidylserines; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate | 1989 |
ADP and, indirectly, ATP are potent inhibitors of cAMP production in intact isoproterenol-stimulated C6 glioma cells.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adenylate Cyclase Toxin; Animals; Cyclic AMP; Glioma; GTP-Binding Proteins; Hydrolysis; Isoproterenol; Pertussis Toxin; Rats; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1989 |
Cell type-specific control of human neuronectin secretion by polypeptide mediators and phorbol ester.
Topics: Antibodies, Monoclonal; Extracellular Matrix; Extracellular Matrix Proteins; Fibroblast Growth Factors; Fibroblasts; Glioma; Growth Substances; Humans; Immunologic Techniques; In Vitro Techniques; Nerve Growth Factors; Nerve Tissue Proteins; Neuroblastoma; Neuroectodermal Tumors, Primitive, Peripheral; Sarcoma, Ewing; Secretory Rate; Tetradecanoylphorbol Acetate; Transforming Growth Factors; Tumor Necrosis Factor-alpha | 1989 |
Bradykinin-induced generation of inositol 1,4,5-trisphosphate in fibroblasts and neuroblastoma cells: effect of pertussis toxin, extracellular calcium, and down-regulation of protein kinase C.
Topics: Adenosine Diphosphate Ribose; Bradykinin; Calcium; Enzyme Activation; Fibroblasts; Glioma; GTP-Binding Proteins; Hybrid Cells; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Neuroblastoma; Pertussis Toxin; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoinositide Phospholipase C; Phosphoric Diester Hydrolases; Protein Kinase C; Sugar Phosphates; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1988 |
Phorbol esters and beta-adrenergic agonists mediate desensitization of adenylate cyclase in rat glioma C6 cells by distinct mechanisms.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Caenorhabditis elegans Proteins; Carrier Proteins; Cells, Cultured; Concanavalin A; Enzyme Activation; Glioma; Isoproterenol; Phorbols; Phosphorylation; Protein Kinase C; Protein Kinases; Rats; Receptors, Adrenergic, beta; Receptors, Drug; Receptors, Immunologic; Tetradecanoylphorbol Acetate | 1985 |
Phorbol ester inhibits bradykinin-stimulated inositol trisphosphate formation and calcium mobilization in neuroblastoma x glioma hybrid NG108-15 cells.
Topics: Bradykinin; Calcium; Cell Line; Diglycerides; Glioma; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Neuroblastoma; Protein Kinase C; Receptors, Bradykinin; Receptors, Neurotransmitter; Sugar Phosphates; Tetradecanoylphorbol Acetate; Thionucleotides; Type C Phospholipases | 1987 |
Phosphatidylethanol biosynthesis in ethanol-exposed NG108-15 neuroblastoma X glioma hybrid cells. Evidence for activation of a phospholipase D phosphatidyl transferase activity by protein kinase C.
Topics: Animals; Cell Line; Enzyme Activation; Ethanol; Glioma; Glycerophospholipids; Hybrid Cells; Kinetics; Neuroblastoma; Phosphatidic Acids; Phospholipase D; Phospholipases; Protein Kinase C; Tetradecanoylphorbol Acetate | 1989 |
Alterations of phospholipid metabolism by phorbol esters and fatty acids occur by different intracellular mechanisms in cultured glioma, neuroblastoma, and hybrid cells.
Topics: Animals; Cell Line; Choline; Ethanolamine; Ethanolamines; Fatty Acids; Glioma; Hybrid Cells; Kinetics; Neuroblastoma; Phosphatidylcholines; Phospholipids; Subcellular Fractions; Tetradecanoylphorbol Acetate | 1989 |
Ribosomal protein S6 phosphorylation and morphological changes in response to the tumour promoter 12-O-tetradecanoylphorbol 13-acetate in primary human tumour cells, established and transformed cell lines.
Topics: Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Fibroblasts; Glioma; Humans; Meningeal Neoplasms; Meningioma; Neoplasms; Phosphorylation; Ribosomal Proteins; Simian virus 40; Tetradecanoylphorbol Acetate | 1985 |
Modifications of phospholipid metabolism induced by chlorpromazine, desmethylimipramine and propranolol in C6 glioma cells.
Topics: Animals; Cell Line; Chlorpromazine; Desipramine; Diglycerides; Dose-Response Relationship, Drug; Glioma; Phosphatidylinositol Phosphates; Phosphatidylinositols; Phospholipids; Propranolol; Tetradecanoylphorbol Acetate | 1987 |
Down-regulation of protein kinase C in rat glioma C6 cells: effects on the beta-adrenergic receptor-coupled adenylate cyclase.
Topics: Adenylyl Cyclases; Animals; Caenorhabditis elegans Proteins; Carcinogens; Carrier Proteins; Cell Line; Glioma; Kinetics; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Rats; Receptors, Adrenergic, beta; Receptors, Drug; Receptors, Immunologic; Tetradecanoylphorbol Acetate | 1987 |
Concanavalin A prevents phorbol-mediated redistribution of protein kinase C and beta-adrenergic receptors in rat glioma C6 cells.
Topics: Animals; Cell Line; Cell Membrane; Concanavalin A; Cytosol; Glioma; Kinetics; Protein Kinase C; Rats; Receptors, Adrenergic, beta; Tetradecanoylphorbol Acetate | 1987 |
Second stage tumor promoters: differences in biological potency and phorbol ester receptor affinity in C6 cells.
Topics: Animals; Caenorhabditis elegans Proteins; Carcinogens; Carrier Proteins; Cell Line; Cyclic AMP; Diterpenes; Glioma; Glycerolphosphate Dehydrogenase; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Rats; Receptors, Drug; Receptors, Immunologic; Terpenes; Tetradecanoylphorbol Acetate | 1987 |
Bradykinin-activated transmembrane signals are coupled via No or Ni to production of inositol 1,4,5-trisphosphate, a second messenger in NG108-15 neuroblastoma-glioma hybrid cells.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Bradykinin; Calcium; Cell Line; Diglycerides; Glioma; GTP-Binding Proteins; Humans; Hybrid Cells; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Membrane Potentials; Neuroblastoma; Pertussis Toxin; Sugar Phosphates; Tetradecanoylphorbol Acetate; Tetraethylammonium; Tetraethylammonium Compounds; Virulence Factors, Bordetella | 1986 |
A cDNA encoding protein kinase C identifies two species of mRNA in brain and GH3 cells.
Topics: Animals; Antigen-Antibody Complex; beta-Galactosidase; Brain; Cell Line; DNA; Glioma; Immune Sera; Isoenzymes; Molecular Weight; Nucleic Acid Hybridization; Protein Kinase C; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate | 1986 |
Promoting effect of 12-O-tetradecanoylphorbol-13-acetate on neurogenic microtumors initiated by transplacental exposure to N-ethyl-N-nitrosourea.
Topics: Animals; Astrocytoma; Brain Neoplasms; Cocarcinogenesis; Ependymoma; Ethylnitrosourea; Female; Glioma; Male; Maternal-Fetal Exchange; Oligodendroglioma; Placenta; Pregnancy; Rats; Tetradecanoylphorbol Acetate | 1987 |
Growth of tumor colonies mediated by phorbol ester and 13-cis retinoic acid in mixed cultures.
Topics: Animals; Cell Communication; Cell Differentiation; Cell Division; Cell Line; Fibroblasts; Glioma; Neuroblastoma; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1987 |
Quantitation of protein kinase C by immunoblot--expression in different cell lines and response to phorbol esters.
Topics: Animals; Antigen-Antibody Complex; Cattle; Cell Line; Glioma; Humans; Immunologic Techniques; Mice; Neuroblastoma; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Rabbits; Rats; Tetradecanoylphorbol Acetate | 1987 |
Differential regulation of phosphatidylcholine biosynthesis by 12-O-tetradecanoylphorbol-13-acetate and diacylglycerol in NG108-15 neuroblastoma x glioma hybrid cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Choline; Chromatography, High Pressure Liquid; Diglycerides; Glioma; Glycerides; Hybrid Cells; Isoquinolines; Neuroblastoma; Phosphatidylcholines; Piperazines; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1987 |
Phosphatidylcholine biosynthesis in the neuroblastoma-glioma hybrid cell line NG108-15: stimulation by phorbol esters.
Topics: Animals; Cell Line; Choline; Ethanolamine; Ethanolamines; Glioma; Inositol; Neuroblastoma; Phorbol Esters; Phosphatidylcholines; Rats; Tetradecanoylphorbol Acetate | 1986 |
Glucocorticoid-mediated increases in glycerol phosphate dehydrogenase activity is inhibited by the phorbol ester tumor promoters.
Topics: Animals; Caenorhabditis elegans Proteins; Carrier Proteins; Cell Line; Dexamethasone; Enzyme Induction; Glioma; Glycerolphosphate Dehydrogenase; Oligodendroglia; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Kinase C; Rats; Receptors, Drug; Receptors, Immunologic; Tetradecanoylphorbol Acetate; Theophylline | 1985 |