tetradecanoylphorbol acetate has been researched along with Experimental Neoplasms in 325 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 238 (73.23) | 18.7374 |
| 1990's | 41 (12.62) | 18.2507 |
| 2000's | 24 (7.38) | 29.6817 |
| 2010's | 19 (5.85) | 24.3611 |
| 2020's | 3 (0.92) | 2.80 |
| Authors | Studies |
|---|---|
| Bauer, J; Becker, M; Hahn, H; König, S; Müllen, A; Pyczek, J; Rabe, H; Schön, MP; Uhmann, A | 1 |
| Kreft, M; Krotenberg Garcia, A; Ramovs, V; Sonnenberg, A | 1 |
| Al Matouq, J; Bloom, C; Hansen, LA; Holmes, M; Holmes, TR; Lovas, S; Madson, JG; Nicola, L; Palermo, NY; Rudd, JC; Sioda, N | 1 |
| Aguilar-Pimentel, JA; Beck, PJ; Fuchs, H; Gailus-Durner, V; Garman, KA; Hrabe de Angelis, M; Lee, YG; Ollert, M; Riegel, AT; Schmidt, MO; Schmidt-Weber, C; Tan, M; Tassi, E; Wellstein, A; Zuo, C | 1 |
| Cleary, MP; Hao, J; Landers, VD; Li, B; Li, Q; Liu, L; Mandal, A; Morris, RJ; Rao, E; Sun, Y; Suttles, J; Zeng, J; Zhang, Y | 1 |
| Chakraborty, B; Das, B; Ghosh, SK; Nath, A; Pal, R; Sengupta, M; Singh, LM | 1 |
| Balmain, A; Del Rosario, R; Harris, S; Kandyba, E; Reeves, MQ | 1 |
| Arora, N; Bansal, MP; Koul, A | 1 |
| Chen, HC; Lin, JA; Yen, GC | 1 |
| Angel, JM; Beltran, L; Blando, J; Checkley, LA; Cho, J; DiGiovanni, J; Hursting, SD; Rho, O | 1 |
| Abel, EL; Beltran, L; Bozeman, R; Cheng, T; DiGiovanni, J; Macias, E | 1 |
| Hall, RP; He, Y; Huang, Q; Kato, TA; Li, CY; Li, F; Liu, X | 1 |
| Cao, Y; Chen, C; Fan, F; Lin, C; Liu, Z; Lu, Y; Shan, Y; Shen, C; Sun, L; Tao, Y; Wang, A; Wang, S; Wei, Z; Wu, H; Zheng, S; Zhu, P | 1 |
| Bratton, SB; Cho, J; Dao, CK; DiGiovanni, J; Fischer, SM; Kohno, S; Lago, CU; Lee, S; Mills, EM; Nikawa, T; Nowinski, SM; Rho, O; Riley, CL; Rundhaug, JE; Solmonson, A; Wright, CW | 1 |
| Dai, X; Dang, Y; Gu, J; Liu, M; Liu, X; Ren, X; Wang, L; Xu, P; Ye, X | 1 |
| Anto, RJ; Bava, SV; Cheriyan, VT; Laladhas, KP; Puliappadamba, VT; Unnithan, RG; Vijayammal, PL | 1 |
| Fujiki, H; Suganuma, M | 1 |
| Boily, G; He, XH; Jardine, K; McBurney, MW; Pearce, B | 1 |
| Fujimoto, Y; Iida, T; Yasukawa, K | 1 |
| Cheng, AC; Kuo, DH; Lai, YS; Lo, CY; Pan, MH; Wu, H | 1 |
| Adhikary, G; Crish, JF; Eckert, RL; Jans, R; Rorke, EA | 1 |
| Cui, XY; Dong, CY; Duan, YJ; Gao, WF; Lin, YM; Ma, XT; Yang, BX; Zhang, F | 1 |
| Anson, RM; de Cabo, R; Diéguez, C; Jones, B; López, M; Minor, RK; Pearson, KJ; Younts, CM | 1 |
| Eilers, M; Elsässer, HP; Hönnemann, J; Sanz-Moreno, A; Wolf, E | 1 |
| Ibrahim, S; Levin, B; Meruelo, D; Pellicer, A; Suzme, R; Tseng, JC | 1 |
| Awasthi, P; Colburn, NH; Farrell, L; Lambert, P; Young, MR | 1 |
| Bernabéu, C; Letarte, M; López-Novoa, JM; Pérez-Gómez, E; Quintanilla, M; Ramirez, JR; Romero, D; Velasco, B | 1 |
| Chen, R; Wan, Z; Zhao, X; Zhu, H | 1 |
| Blumberg, PM; Lorenzo, PS; Rambaratsingh, RA; Stone, JC | 1 |
| Bowman, L; Castranova, V; Ding, M; Huang, C; Leonard, S; Lu, Y; Shi, X; Vallyathan, V; Wang, L | 1 |
| Chen, Z; Hicks, J; Honeycutt, KA; Koster, MI; Miers, M; Nuchtern, J; Roop, DR; Shohet, JM | 1 |
| Adachi, S; Iwamoto, R; Mekada, E; Mizushima, H; Ohishi, M; Wang, X | 1 |
| Chen, WT; Li, J; Pan, HY; Zhang, P; Zhang, ZY; Zhou, XJ | 1 |
| Fukuda, Y; Matsunaga, S; Sakai, K; Tanaka, R; Tokuda, H | 1 |
| Eguchi, N; Fukasawa, K; Kikuchi, K; Machida, K; Sawa, N; Suzuki, S; Taguchi, F; Urano, K; Usui, T | 1 |
| Sharma, M; Sharma, PD; Singh, TV; Vyas, S | 1 |
| Kitanaka, S; Miura, M; Motohashi, S; Sun, Y; Tomizawa, N; Yasukawa, K | 1 |
| Hatano, M; Ishiguro, H; Ogura, H; Takimoto, T; Umeda, R | 1 |
| Colburn, NH; Koehler, BA; Nelson, KJ | 1 |
| Reyes-Mayes, D; Volm, M; Wayss, K | 1 |
| Hennings, H; Kulesz-Martin, M; Lichti, U; Yuspa, SH | 1 |
| Colletta, G; Di Fiore, PP; Ferrentino, M; Pietropaolo, C; Turco, MC; Vecchio, G | 1 |
| Fisher, PB; Mufson, RA; Weinstein, IB | 2 |
| Boutwell, RK; Perchellet, JP | 1 |
| Nelson, KG; Slaga, TJ | 1 |
| Klein-Szanto, AJ; Nelson, KG; Shah, Y; Slaga, TJ | 1 |
| Bleackley, RC; Havele, C; Horak, H; McElhaney, J; Paetkau, VH; Shaw, AR; Turner, AR | 1 |
| Braun, SJ; Marko, M; Parsons, DF; Wansor, KJ | 1 |
| Dokhelar, MC; Garson, D; Tabilio, A; Testa, U; Tursz, T; Vainchenker, W; Wakasugi, H | 1 |
| Fischer, SM; Mills, GD; Slaga, TJ | 2 |
| Ashendel, CL; Boutwell, RK; Verma, AK | 1 |
| Ludwig, KW; Niles, RM | 1 |
| Lotan, D; Lotan, R | 1 |
| Salomon, DS | 1 |
| Benfield, JR; Cohen, AH; Fu, PC; Hammond, WG; Jensen, T; Pak, HY; Paladugu, RR; Shors, EC; Teplitz, RL | 1 |
| Belman, S; Garte, SJ | 1 |
| Brostrom, CO; Brostrom, MA; Brotman, LA; Geller, HM; Lee, C; Wolff, DJ | 1 |
| Costa, J; Hamilton, V; Klein, G; Rabson, AS; Yee, C | 1 |
| Boutwell, RK; Conrad, EA; Verma, AK | 1 |
| Abutbul, H; Rotter, V; Wolf, D | 1 |
| Albert, RE; Burns, FJ | 1 |
| Davidson, K; Mamrack, M; Nelson, K; Reiners, J; Slaga, T | 1 |
| Rivedal, E; Sanner, T | 1 |
| Graff, DE; Miller, RE; O'Connell, JF; Pitt, JF; Weiss, HS | 1 |
| Daniel, LW; Kucera, LS; Waite, M | 1 |
| Abe, E; Chida, K; Kuroki, T; Sasaki, K; Suda, T | 1 |
| Chudomel, V; Malasková, V; Soucek, J; Stöckbauer, P | 1 |
| Klein-Szanto, A; Nettesheim, P; Terzaghi, M | 1 |
| Argyris, TS | 2 |
| Bernfeld, P; Homburger, F | 1 |
| Ashendel, CL; Boutwell, RK; Garcia, CT; Verma, AK | 1 |
| Albert, RE; Burns, FJ; Morris, EP | 1 |
| Pai, SB; Steele, VE; Topping, DC | 1 |
| Kirch, ME; Miller, RA; Palladino, MA; Pearlstein, KT; Pelus, LM; Staiano-Coico, L; Stutman, O | 1 |
| Habs, M; Schmähl, D; Wagner, G | 1 |
| Dutton, RW; Swain, SL; Wetzel, GD | 1 |
| Goerttler, K; Hesse, B; Loehrke, H; Schweizer, J | 4 |
| Stenbäck, F | 3 |
| Curtis, GL; Heidrick, ML; Ryan, WL; Stenback, F | 1 |
| Fischer, SM; Klein-Szanto, AJ; Major, S; Nelson, K; Slaga, TJ; Weeks, CE | 1 |
| Fischer, SM; Gleason, GL; Nelson, K; Slaga, TJ | 1 |
| Nettesheim, P; Topping, DC | 1 |
| Boger, E; Moolten, FL; Rizzone, A; Schreiber, B; Weiss, AJ | 1 |
| Peto, R; Shubik, P; Stenbäck, F | 3 |
| Morgan, DL; Yuspa, SH | 1 |
| Klein-Szanto, AJ; Slaga, TJ; Triplett, LL; Trosko, KE; Yotti, LP | 1 |
| Goerttler, K; Hesse, B; Loehrke, H; Milz, A; Schweizer, J | 1 |
| Donahoe, R; Ferguson, E; Geusz, S; Hennings, H; Spangler, EF; Wenk, M; Yuspa, SH | 1 |
| Arrick, BA; Cohn, ZA; Griffith, OW; Nathan, CF | 1 |
| Ashendel, CL; Astrup, E; Boutwell, RK; Verma, AK | 1 |
| Verma, AK | 1 |
| Komitowski, D | 1 |
| Boutwell, RK; Simsiman, RC; Takigawa, M; Verma, AK | 1 |
| Buhler, DR; Chang, RL; Conney, AH; Jerina, DM; Levin, W; Newman, MS; O'Malley, RF; Slaga, TJ; Wood, AW | 1 |
| Froscio, M; Guy, GR; Jones, MJ; Murray, AW; Pappalardo, S; Tapley, PM | 1 |
| Bolmer, SD; Wolf, G | 1 |
| Fujiki, H; Matsukura, N; Suganuma, M; Sugimura, T; Takayama, S | 1 |
| Benjamin, WR; Farrar, JJ; Steeg, PS | 1 |
| Lindquist, RR; Munger, WE | 1 |
| Hosoda, Y; Iseki, H; Kato, R; Nakadate, T; Sonoda, S; Takemura, S; Ura, A; Yamamoto, S | 1 |
| Herrmann, AL; Nelson, FR; Slaga, TJ; Weeks, CE | 1 |
| Fürstenberger, G; Marks, F; Sorg, B | 1 |
| Clark, JN; Levin, LV; Newberne, PM; Quill, HR; Wolf, G | 1 |
| Boutwell, RK; DiGiovanni, J | 1 |
| Melchionne, S; Van Duuren, BL | 1 |
| Chouroulinkov, I; Coulomb, H; Grover, PL; MacNicoll, AD; Sims, P | 1 |
| Ikenami, M; Mizuno, D; Tsunawaki, S; Yamazaki, M | 1 |
| Belman, S | 1 |
| Boone, CW; Scott, RE | 1 |
| Bash, JA; Baxter, CS; Ferguson, TA; Fish, LA; Michael, JG | 1 |
| Forbes, IJ; Valente, L; Zalewski, PD | 1 |
| Brukner, L; Cohn, Z; Kaplan, G; Nathan, C; Unkeless, J | 1 |
| Cohn, Z; Nathan, C | 1 |
| Chambers, DA; Krueger, GG; Shelby, J | 1 |
| Blumberg, PM | 1 |
| Fry, RJ; Grube, D; Ley, RD; Staffeldt, E | 1 |
| Dzarlieva, RT; Fusenig, NE | 1 |
| Fischer, SM; Klein-Szanto, AJ; Mamrack, M; Nelson, K; Slaga, TJ; Weeks, CE | 1 |
| Hecker, E; Keist, R; Keller, R; Köppel, P | 1 |
| Ferioli, ME; Scalabrino, G | 1 |
| Elkind, MM; Han, A | 1 |
| Diamond, L; O'Brien, TG; Saladik, D | 1 |
| Boorman, GA; Dean, JH; Lauer, LD; Leubke, RW; Luster, MI | 1 |
| Hecker, E; Schmidt, R | 1 |
| Fiorentini, KM; Fu, PP; Lu, AY; Wislocki, PG; Yang, SK | 1 |
| Boutwell, RK | 1 |
| Currens, M; Iype, PT; Ray-Chaudhuri, R | 1 |
| Bennett, M; Fredrickson, GG | 1 |
| Anderson, WB; Cooper, HL; Kraft, AS; Sando, JJ | 1 |
| Logani, MK; Slaga, TJ; Solanki, V | 1 |
| Fürstenberger, G; Ganss, M; Marks, F; Seemann, D | 1 |
| Hennings, H; Lichti, U; Morgan, D; Yuspa, SH | 1 |
| Arrick, BA; Cohn, ZA; DeSantis, NM; Murray, HW; Nathan, CF | 1 |
| Gidlund, M; Jansson, M; Nilsson, K; Orn, A; Pattengale, PK; Wigzell, H | 1 |
| Boutwell, RK; Digiovanni, J; Hoel, MJ | 1 |
| Marchok, AC; Nettesheim, P; Steele, VE | 1 |
| Boutwell, RK; Verma, AK | 3 |
| Colburn, NH; De Luca, LM; Dion, LD | 1 |
| Chan, RL; Chao, WR; Dawson, MI; Hobbs, PD | 1 |
| Buening, MK; Chang, RL; Conney, AH; Jerina, DM; Lehr, RE; Levin, W; Taylor, CW; Wood, AW; Yagi, H | 1 |
| Blumberg, PM; Driedger, PE | 2 |
| Barbin, A; Bartsch, H; Croisy, A; Malaveille, C; Tomatis, L; Zajdela, F | 1 |
| Daub, GH; Iyer, RP; Lyga, JW; Secrist, JA; Slaga, TJ | 1 |
| Bohrman, JS; Fischer, SM; Gleason, GL; Slaga, TJ | 1 |
| Chao, WR; Dawson, MI; Fung, VA; Helmes, CT; Hobbs, PD; Kuhlmann, K | 1 |
| Fodstad, O; Johannessen, JV; Olsnes, S; Tveit, KM | 1 |
| Fischer, SM; Gleason, GL; Mills, GD; Slaga, TJ | 1 |
| Chao, WR; De Young, LM; Helmes, CT; Miller, V; Young, JM | 1 |
| Hirao, Y; Hopp, L; Izumi, K; Oyasu, R | 1 |
| Chang, RL; Conney, AH; Croisy-Delcey, M; Ittah, Y; Jerina, DM; Levin, W; Wood, AW; Yagi, H | 1 |
| Fujikawa-Yamamoto, K; Gai, XD; Odashima, S; Tanino, M; Teraoka, K; Yamagishi, H; Zong, ZP | 1 |
| Fong, HH; Gerhäuser, C; Kinghorn, AD; Kosmeder, J; Lee, SK; Luo, Y; Luyengi, L; Mar, W; Moriarty, RM; Suh, N | 1 |
| Furuke, K; Inamoto, T; Iwata, S; Kitaoka, Y; Matsuda, M; Nakamura, H; Ozawa, K; Toda, K; Yamaoka, Y; Yodoi, J | 1 |
| Armellini, R; Guerrieri, P; Liotti, FS; Mariucci, G; Menghini, AR | 1 |
| Agarwal, R; Katiyar, SK; Mukhtar, H | 1 |
| Blumberg, PM; Goodnight, JA; Kazanietz, MG; Kolch, W; Martiny-Baron, G; Mischak, H; Mushinski, JF; Pierce, JH; Schaechtle, C | 1 |
| Hargrove, ME; Shiver, J; Ting, CC; Wu, J | 1 |
| Desai, KN; Lamartiniere, CA; Wei, H | 1 |
| Anisimov, VN; Sheiko, EV | 1 |
| Salwa, J | 1 |
| Koshimizu, K; Murakami, A; Nakamura, Y; Ohigashi, H | 1 |
| Honn, KV; Tang, DG | 1 |
| Conney, AH; Frenkel, K; Grunberger, D; Han, J; Huang, MT; Ma, W; Xie, JG; Yen, P | 1 |
| Bol, DK; DiGiovanni, J; Gimenez-Conti, I; Kiguchi, K; Rupp, T | 1 |
| de Vries, A; Dortant, PM; Kroese, ED; van der Houven van Oordt, CW; van Kranen, HJ; van Kreijl, CF; van Oostrom, CT; van Steeg, H; Wester, PW | 1 |
| Daulhac, L; Kowalski-Chauvel, A; Pradayrol, L; Seva, C; Vaysse, N | 1 |
| Becker, K; Gregel, CM; Kaina, B | 1 |
| Coulter, K; Morris, RJ; Steinberg, SR; Tryson, K | 1 |
| Chang, RL; Conney, AH; Huang, MT; Liu, Y; Lou, YR; Newmark, HL; Osawa, T; Xie, JG | 1 |
| Alameda, F; Batlle, E; de Herreros, AG; del Mont Llosas, M; Díaz, V; Domínguez, D; Loukili, N; Paciucci, R; Verdú, J | 1 |
| Higashi-Okai, K; Okai, Y; Otani, S | 1 |
| Chun, KS; Kang, JY; Lee, E; Lee, JM; Lee, SS; Park, KK; Surh, YJ | 1 |
| Bowen, R; Lebwohl, M; Wei, H; Zhang, X | 1 |
| Baykut, F; Berkarda, B; Koyuncu, H; Soybir, G | 1 |
| Bomser, JA; Singletary, KW; Smith, MA; Wallig, MA | 1 |
| Conti, CJ; Gimenez-Conti, IB; Johnson, DG; Pierce, AM; Russell, JL; Schneider-Broussard, R | 1 |
| Akihisa, T; Takido, M; Yasukawa, K; Yoshida, ZY | 1 |
| Liang, YC; Lin, JK | 1 |
| Chiou, JF; Lee, MH; Yang, LL; Yen, KY | 1 |
| Agadir, A; Bai, L; Chandraratna, RA; Chao, W; Chen, G; Dawson, MI; Dousman, L; Gu, J; Hill, DL; Hobbs, PD; Jong, L; Merchant, JL; Park, JH; Shroot, B; Thacher, SM; Toll, L; Verma, AK; Waleh, N; Zhang, X | 1 |
| Goerttler, K; Hesse, B; Löhrke, H | 1 |
| Blasco, MA; Flores, JM; González-Suárez, E; Jorcano, JL; Martín-Caballero, J; Ramírez, A; Samper, E | 1 |
| Angel, P; Breitenbach, U; Christofori, G; Fürstenberger, G; Gebhardt, C; Richter, KH; Tuckermann, JP | 1 |
| Ma, RD; Yu, LJ; Yu, TX | 1 |
| Covelli, V; Dragani, TA; Galbiati, F; Mancuso, MT; Manenti, G; Pazzaglia, S; Peissel, B; Rebessi, S; Saran, A; Spinola, M; Zaffaroni, D; Zanesi, N | 1 |
| Coleman, CS; Guo, Y; Megosh, LC; O'Brien, TG; Pegg, AE; Sawicki, JA | 1 |
| Bias, NE; Helson, L; Kopelovich, L | 1 |
| Chouroulinkov, I; Lasne, C | 1 |
| Goerttler, K; Loehrke, H; Schweizer, J | 1 |
| DiGiovanni, J; Gleason, GL; Harvey, RG; Slaga, TJ; Sukumaran, KB | 1 |
| Melchionne, S; Segal, A; Seidman, I; Smith, AC; Tseng, SS; Van Duuren, BL | 1 |
| Bracken, WM; Gleason, GL; Hennings, H; Slaga, TJ; Weeks, CE | 1 |
| Nettesheim, P; Terzaghi, M | 1 |
| Chouroulinkov, I; Gentil, A; Grover, PL; Sims, P; Tierney, B | 1 |
| Armuth, V; Berenblum, I | 2 |
| Balmain, A; Hecker, E | 1 |
| Goerttler, K; Löhrke, H | 1 |
| Boutwell, RK; De Young, LM; Mufson, RA | 1 |
| Boutwell, RK; Mufson, RA; Simsiman, RC | 1 |
| Berry, DL; DiGiovanni, J; Juchau, MR; Slaga, TJ | 1 |
| Edwards, CA; Martin, RG; Setlow, VP; Vembu, D | 1 |
| Boutwell, RK; Fischer, SM; Gleason, GL; Mufson, RA; Slaga, TJ; Verma, AK | 1 |
| Hecht, SS; Hirota, N; Hoffmann, D; LaVole, E; Mazzarese, R; Ohmori, T | 1 |
| Goldschmidt, BM; Loewengart, G; Melchionne, S; Roth, D; Seldman, I; Smith, AC; Van Duuren, BL | 1 |
| Fusenig, NE; Murray, AW | 1 |
| Brukner, LH; Cohn, ZA; Nathan, CF; Silverstein, SC | 1 |
| Nims, R; Viguera, C; Yuspa, SH | 1 |
| Argyris, TS; De Young, LM; Gordon, GB | 1 |
| Marks, F; Schweizer, J | 1 |
| Griesemer, RA; Nelson, FR; Nettesheim, P; Pal, BC; Topping, DC | 1 |
| Buening, MK; Chang, RL; Conney, AH; Jerina, DM; Karle, JM; Levin, W; Wood, AW; Yagi, H | 1 |
| Bresnick, E; Lamden, M; Meunier, P | 1 |
| Gleason, GL; Hardin, L; Slaga, TJ | 1 |
| Buening, MK; Chang, RL; Conney, AH; Jerina, DM; Levin, W; Thakker, DR; Wood, AW | 1 |
| Keller, R | 1 |
| Bates, JR; Bruegge, WF; Colburn, NH; Gray, RH; Kelsey, WH; Rossen, JD; Shimada, T | 1 |
| Bracken, WM; Conney, AH; Dresner, S; Jerina, DM; Levin, W; Slaga, TJ; Yagi, H | 1 |
| Boutwell, RK; Rice, HM; Shapas, BG; Verma, AK | 2 |
| Melchionne, SM; Smith, AC; Van Duuren, BL | 1 |
| Maté, U; Melchionne, S; Segal, A; Seidman, I; Smith, A; Solomon, JJ; Van Duuren, BL | 1 |
| Hecht, SS; Hirota, N; Hoffmann, D; Loy, M | 1 |
| Chang, RL; Conney, AH; Jerina, DM; Lehr, RE; Levin, W; Thakker, DR; Wood, AW | 1 |
| Berry, DL; Bracken, WM; Fischer, SM; Slaga, TJ; Viaje, A | 1 |
| Hecht, SS; Hirota, N; Hoffman, D | 1 |
| Fry, RJ; Grube, DD; Ley, RD | 1 |
| Ashendel, CL; Astrup, EG; Boutwell, RK; DeYoung, LM; O'Brien, TG; Verma, AK; Weekes, RG | 1 |
| Pienta, RJ; Poiley, JA; Raineri, R | 1 |
| Bracken, WJ; Conney, AH; Gleason, G; Jerina, DM; Levin, W; Slaga, TJ; Yagi, H | 1 |
| Segal, A; Van Duuren, BL | 1 |
| Albert, RE; Burns, FJ; Sivak, A; Vanderlaan, M | 1 |
| Goerttler, L; Loehrke, H | 1 |
| Palmes, ED | 1 |
| Scribner, JD; Slaga, TJ; Viaje, A | 1 |
| Goerttler, K; Loehrke, H | 3 |
| Chang, CC; Chu, EH; Trosko, JE; Yotti, LP | 1 |
| Alonso, A; Balmain, A; Fischer, J | 1 |
| Slaga, TJ; Viaje, A; Weinstein, IB; Wigler, M | 1 |
| Chang, RL; Conney, AH; Jerina, DM; Levin, W; Slaga, TJ; Wood, AW; Yagi, H | 1 |
| Berry, DL; Bracken, WM; Fischer, SM; Leclerc, SM; Miller, DR; Slaga, TJ; Viaje, A | 1 |
| Bracken, WM; Conney, AH; Jerina, DM; Levin, W; Slaga, TJ; Viaje, A; Yagi, H | 1 |
| Chouroulinkov, I; Gentil, A; Grover, PL; Sims, P | 1 |
| Bhisey, RA; Sirsat, SM | 1 |
| Colburn, NH; Head, R; Lau, S | 1 |
| Boutwell, RK; Bowden, GT; Slaga, TJ | 1 |
| Norris, JS; Schwartz, DA | 1 |
| Kumar, S; Rani, AS | 1 |
| Bowden, C; Coene, MC; De Coster, R; End, D; Krekels, M; Van Ginckel, R; Wouters, W | 1 |
| Kalafut, F; Klobusická, M; Kusenda, J; Novotná, L | 1 |
| Loktionov, A; Martel, N; Popovich, I; Tomatis, L; Yamasaki, H; Zabezhinski, M | 1 |
| Akinaga, S; Gomi, K; Morimoto, M; Okabe, M; Tamaoki, T | 1 |
| Biozzi, G | 1 |
| Balmain, A; Burns, PA; Haddow, S; Jack, A; Neilson, F | 1 |
| Andrews, DF; Collins, SJ; Reddy, AL | 1 |
| Droms, KA; Malkinson, AM | 1 |
| Suzuki, H; Tunru, IS; Yano, S | 1 |
| Bruce, SA; Bury, MA; Okeda, T; Ts'o, PO; Ueo, H; Yokogawa, Y | 1 |
| Ji, C; Marnett, LJ; Pruess-Schwartz, D; Reddy, A | 1 |
| Gaido, K; Greenlee, WF; Skopek, TR; Walker, C | 1 |
| Burrill, C; LaVoie, EJ; Rice, JE; Weyand, EH | 1 |
| Johnson, HM; Torres, BA | 1 |
| Howe, RC; Russell, JH | 1 |
| Housey, GM; Johnson, MD; Kirschmeier, PT; O'Brian, CA; Weinstein, IB | 1 |
| Perchellet, JP; Satyamoorthy, K | 1 |
| Iwashima, A; Nakagawa, Y; Nishino, H; Takayasu, J; Yamaoka, Y | 1 |
| De Luca, LM; Shores, RL; Spangler, EF; Wenk, ML | 1 |
| Anisimov, V; Likhachev, A; Loktionov, A; Napalkov, N; Tomatis, L; Zabezhinski, M | 2 |
| Fukusen, N; Ishidoh, K; Kato, Y; Katunuma, N; Kido, H | 1 |
| Abrahamsson, L; Esscher, T; Jergil, B; Mattsson, M; Påhlman, S; Ruusala, AI | 1 |
| Housey, GM; Johnson, MD; Krauss, RS; Weinstein, IB | 1 |
| Colburn, NH; Kligman, D; Patel, J; Simek, SL | 1 |
| Obom, KM; Pogo, BG | 1 |
| Campq, MS; Smith, KT | 1 |
| Lichtenstein, A | 2 |
| Fujiki, H | 1 |
| Giese, G; Traub, P | 1 |
| Altom, MG; Nanda, SK; Schultz, RM | 1 |
| Amtmann, E; Knapp, A; Müller, K; Sauer, G | 1 |
| Babiss, LE; Fisher, PB | 1 |
| Young, AR | 1 |
| Kestenbach, U; Köpf-Maier, P | 1 |
| Fujiki, H; Iwashima, A; Kitagawa, K; Nishino, H | 1 |
| Celada, A; Schreiber, RD | 1 |
| Adams, DO; Becton, DL; Celada, A; Hamilton, TA; Schreiber, RD; Somers, SD | 1 |
| Devor, D; Hennings, H; Rehm, S; Ward, JM; Wenk, ML | 1 |
| Akagawa, KS; Kamoshita, K; Onodera, S; Tokunaga, T | 1 |
| Loft, H; Nolte, H; Stahl Skov, P | 1 |
| Endo, Y; Fujiki, H; Hasegawa, M; Hirota, M; Horiuchi, T; Nakayasu, M; Shudo, K; Suganuma, M; Yoshizawa, S | 1 |
| Adams, DO; Lewis, JG | 1 |
| Wolf, G; Zerlauth, G | 1 |
| Dale, IL; Gescher, A; Lazenby, CM | 1 |
| Adams, DO; Somers, SD | 1 |
| Kodama, M | 1 |
| Bowden, GT; Breathnach, R; Briand, JP; Fürstenberger, G; Krieg, P; Leroy, P; Matrisian, LM | 1 |
| Chan, J; Chow, DA | 1 |
| Birnboim, HC; Burns, BF; Kadhim, S | 1 |
| Naroditskiĭ, BS; Ponomarev, TI; Potebnia, GP; Struk, VI; Tikhonenko, TI | 1 |
| Bowden, GT; Jaffe, DR | 1 |
| Birt, DF; Bresnick, E; Tibbels, MG; Walker, B | 1 |
| Fishman, M; Gunther, G | 1 |
| LaHann, TR | 1 |
| Devor, D; Quander, R; Spangler, EF; Ward, JM; Wenk, ML | 1 |
| Adams, DO; Dean, JH; Lauer, LD; Luebke, RW; Luster, MI; Murray, MJ | 1 |
| Wattenberg, LW | 1 |
| Yamasaki, H | 1 |
| Buzhievskaia, TI; Bykorez, AI; Kononenko, LI; Lukash, LL; Shapiro, NI | 1 |
| Gibbs, NK; Magnus, IA; Young, AR | 1 |
17 review(s) available for tetradecanoylphorbol acetate and Experimental Neoplasms
| Article | Year |
|---|---|
Carcinogenic aspects of protein phosphatase 1 and 2A inhibitors.
Topics: Animals; Carcinogens; Disease Progression; Enzyme Inhibitors; Humans; Marine Toxins; Mice; Models, Molecular; Neoplasms; Neoplasms, Experimental; Okadaic Acid; Oxazoles; Protein Phosphatase 1; Protein Phosphatase 2; Rats; Skin Neoplasms; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2009 |
Mouse skin: a useful model system for studying the mechanism of chemical carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alkylating Agents; Animals; Carcinogens; Cell Communication; Cell Differentiation; Cell Division; Cocarcinogenesis; DNA; Indomethacin; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Polyamines; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin | 1982 |
In vitro studies on the mode of action of the phorbol esters, potent tumor promoters, part 2.
Topics: Animals; Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; Clone Cells; DNA Repair; Models, Biological; Mutagens; Mutation; Neoplasms, Experimental; Phorbol Esters; Phorbols; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1981 |
Studies on the multistage nature of radiation carcinogenesis.
Topics: Animals; Carcinogens; Cocarcinogenesis; Dose-Response Relationship, Radiation; Harderian Gland; Humans; Lacrimal Apparatus Diseases; Methoxsalen; Mice; Neoplasms, Experimental; Neoplasms, Radiation-Induced; Radiation, Ionizing; Sarcoma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 1982 |
Phenotypic and chromosomal alterations in cell cultures as indicators of tumor-promoting activity.
Topics: Animals; Carcinogens; Cell Adhesion; Cell Communication; Cell Differentiation; Cell Division; Cell Membrane; Cell Transformation, Neoplastic; Cells, Cultured; Chromosome Aberrations; Cocarcinogenesis; Fibronectins; Humans; Neoplasms, Experimental; Ornithine Decarboxylase; Plasminogen Activators; Tetradecanoylphorbol Acetate; Tretinoin | 1982 |
Specificity and mechanism(s) of promoter inhibitors in multistage promotion.
Topics: Animals; Carcinogens; Cocarcinogenesis; Diterpenes; Epidermal Cells; Fluocinolone Acetonide; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Phorbol Esters; Polyamines; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate; Tosylphenylalanyl Chloromethyl Ketone; Tretinoin | 1982 |
Polyamines in mammalian tumors. Part I.
Topics: Adenosylmethionine Decarboxylase; Animals; Carcinogens; Cells, Cultured; Liver Neoplasms; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Polyamines; Rats; Skin Neoplasms; Spermidine Synthase; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Tumor Virus Infections | 1981 |
Green tea and skin--anticarcinogenic effects.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Antineoplastic Agents; Dermatitis; Humans; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Skin Neoplasms; Tea; Tetradecanoylphorbol Acetate | 1994 |
Adhesion molecules and tumor cell-vasculature interactions: modulation by bioactive lipid molecules.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Animals; Cell Adhesion; Cell Adhesion Molecules; Cytoskeletal Proteins; Endothelium, Vascular; Enzyme Activation; Extracellular Matrix; Female; Humans; Isoenzymes; Male; Mice; Neoplasm Metastasis; Neoplasm Proteins; Neoplasms; Neoplasms, Experimental; Neoplastic Cells, Circulating; Organ Specificity; Protein Kinase C; Tetradecanoylphorbol Acetate; Up-Regulation | 1996 |
Some perspectives on dietary inhibition of carcinogenesis: studies with curcumin and tea.
Topics: Animals; Anticarcinogenic Agents; Arachidonic Acid; Calcitriol; Carcinogens; Cell Differentiation; Chemoprevention; Curcumin; Diet; Humans; Mice; Neoplasms, Experimental; Tea; Tetradecanoylphorbol Acetate; Tretinoin | 1997 |
Cancer chemoprevention by tea polyphenols.
Topics: Animals; Anticarcinogenic Agents; Caffeine; Flavonoids; Humans; Mice; Neoplasms, Experimental; Neoplasms, Radiation-Induced; Phenols; Phytotherapy; Polymers; Polyphenols; Tea; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 2000 |
Experimental studies with liarozole (R 75,251): an antitumoral agent which inhibits retinoic acid breakdown.
Topics: Animals; Antineoplastic Agents; Cell Division; Humans; Imidazoles; Neoplasms, Experimental; Plasminogen Activators; Testosterone; Tetradecanoylphorbol Acetate; Tretinoin | 1992 |
Comparative genetic mechanisms of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced tumors.
Topics: Animals; Cocarcinogenesis; Cytochrome P-450 Enzyme System; Dioxins; Enzyme Induction; Epidermis; Female; Gene Expression Regulation; Humans; Male; Mice; Mice, Hairless; Neoplasms, Experimental; Polychlorinated Dibenzodioxins; Rats; Rats, Inbred Strains; Receptors, Aryl Hydrocarbon; Receptors, Drug; Tetradecanoylphorbol Acetate | 1990 |
Aspects of psoralen phototumorigenesis with emphasis on the possible role of tumour promotion.
Topics: Animals; Cross-Linking Reagents; DNA; Furocoumarins; Methoxsalen; Neoplasms, Experimental; Ornithine Decarboxylase; Oxygen; Photochemistry; PUVA Therapy; Singlet Oxygen; Skin Neoplasms; Superoxides; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 1986 |
Tumor promotion, vitamin A, and fibronectin. A review of recent work.
Topics: Animals; Fibronectins; Humans; Neoplasms, Experimental; Phosphorylation; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vitamin A | 1988 |
[Biophysics of the neoplastic process].
Topics: Animals; Carcinogens; Carcinogens, Environmental; Cell Transformation, Neoplastic; Colonic Neoplasms; DNA; Free Radicals; Humans; Neoplasms, Experimental; Peptide Chain Termination, Translational; Smoking; Tetradecanoylphorbol Acetate | 1986 |
Chemoprevention of cancer.
Topics: Animals; Antineoplastic Agents; Biotransformation; Carcinogens; Drug Administration Schedule; Humans; Neoplasms; Neoplasms, Experimental; Skin Neoplasms; Smoking; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1985 |
308 other study(ies) available for tetradecanoylphorbol acetate and Experimental Neoplasms
| Article | Year |
|---|---|
WIF1 Suppresses the Generation of Suprabasal Cells in Acanthotic Skin and Growth of Basal Cell Carcinomas upon Forced Overexpression.
Topics: Adaptor Proteins, Signal Transducing; Animals; Carcinoma, Basal Cell; Cell Proliferation; Culture Media, Conditioned; Epidermis; Gene Knockdown Techniques; HEK293 Cells; Humans; Keratinocytes; Mice; Neoplasms, Experimental; Primary Cell Culture; Skin Neoplasms; Tamoxifen; Tetradecanoylphorbol Acetate; Tretinoin | 2020 |
Integrin α3β1 Is a Key Regulator of Several Protumorigenic Pathways during Skin Carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Adhesion; Cell Adhesion Molecules; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Epidermis; Humans; Integrin alpha3beta1; Kalinin; Keratinocytes; Mice; Neoplasms, Experimental; Signal Transduction; Skin Neoplasms; Spheroids, Cellular; Tetradecanoylphorbol Acetate; Tetraspanin 24 | 2021 |
Targeting 14-3-3ε activates apoptotic signaling to prevent cutaneous squamous cell carcinoma.
Topics: 14-3-3 Proteins; 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Apoptosis; Carcinogens; Carcinoma, Squamous Cell; cdc25 Phosphatases; Cell Line, Tumor; Cytoplasm; Female; Humans; Keratinocytes; Male; Mice; Mice, Knockout; Neoplasms, Experimental; Protein Multimerization; Skin Neoplasms; Tetradecanoylphorbol Acetate; Xenograft Model Antitumor Assays | 2021 |
The Role of Fibroblast Growth Factor-Binding Protein 1 in Skin Carcinogenesis and Inflammation.
Topics: Animals; Bone Marrow; Bone Marrow Transplantation; Carcinogenesis; Carcinogens; Carrier Proteins; Female; Humans; Inflammation; Intercellular Signaling Peptides and Proteins; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neoplasms, Experimental; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Up-Regulation; Water Loss, Insensible; Wound Healing | 2018 |
Epidermal FABP Prevents Chemical-Induced Skin Tumorigenesis by Regulation of TPA-Induced IFN/p53/SOX2 Pathway in Keratinocytes.
Topics: Animals; Carcinogenesis; Epidermis; Fatty Acid-Binding Proteins; Gene Expression Regulation, Neoplastic; Interferon-beta; Keratinocytes; Male; Mice; Mice, Inbred C57BL; Neoplasm Proteins; Neoplasms, Experimental; RNA, Neoplasm; Skin Neoplasms; SOXB1 Transcription Factors; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53 | 2018 |
Anticancer efficacy of noble metal nanoparticles relies on reprogramming tumor-associated macrophages through redox pathways and pro-inflammatory cytokine cascades.
Topics: Animals; Antineoplastic Agents; Cell Differentiation; Cellular Reprogramming; Cytokines; Gold; Humans; Inflammation Mediators; Macrophages; Metal Nanoparticles; Methylcholanthrene; Mice; Neoplasms, Experimental; Oxidation-Reduction; Signal Transduction; Silver; Skin Neoplasms; Tetradecanoylphorbol Acetate; Th1 Cells; Th2 Cells | 2018 |
Multicolour lineage tracing reveals clonal dynamics of squamous carcinoma evolution from initiation to metastasis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cell Lineage; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Clonal Evolution; Epithelial Cells; Female; Gene Expression Regulation, Neoplastic; Genes, ras; Genetic Predisposition to Disease; Male; Mice, Transgenic; Mutation; Neoplasms, Experimental; Phenotype; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Tumor Burden | 2018 |
Modulatory effects of Azadirachta indica leaf extract on cutaneous and hepatic biochemical status during promotion phase of DMBA/TPA-induced skin tumorigenesis in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Antioxidants; Azadirachta; Cell Transformation, Neoplastic; Cytochrome P-450 Enzyme System; Cytochromes b5; Gene Expression Regulation, Neoplastic; Glutathione Transferase; Lipid Peroxidation; Liver; Male; Mice; Micronucleus Tests; Neoplasms, Experimental; Phytotherapy; Plant Extracts; Plant Leaves; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Xenobiotics | 2013 |
The preventive role of breadfruit against inflammation-associated epithelial carcinogenesis in mice.
Topics: Animals; Anticarcinogenic Agents; Artocarpus; Cyclooxygenase 2; Disease Models, Animal; Epithelial Cells; Female; Inflammation; Mice; Mice, Inbred ICR; Neoplasms, Experimental; Plant Extracts; Tetradecanoylphorbol Acetate | 2014 |
Metformin inhibits skin tumor promotion in overweight and obese mice.
Topics: Adenylate Kinase; Adiponectin; Animals; Body Weight; Carcinogenesis; Carcinoma, Squamous Cell; Diet; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Insulin; Insulin-Like Growth Factor I; Leptin; Mechanistic Target of Rapamycin Complex 1; Metformin; Mice; Mice, Obese; Multiprotein Complexes; Neoplasms, Experimental; Obesity; Overweight; Papilloma; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Sirolimus; Skin Neoplasms; Tetradecanoylphorbol Acetate; TOR Serine-Threonine Kinases | 2014 |
A novel mechanism of skin tumor promotion involving interferon-gamma (IFNγ)/signal transducer and activator of transcription-1 (Stat1) signaling.
Topics: Animals; Anthracenes; Cell Transformation, Neoplastic; Cells, Cultured; Female; Humans; Interferon Regulatory Factor-1; Interferon-gamma; Keratinocytes; Mice; Neoplasms, Experimental; Phosphorylation; Signal Transduction; Skin Neoplasms; STAT1 Transcription Factor; Tetradecanoylphorbol Acetate | 2015 |
Caspase-3 promotes genetic instability and carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bone Marrow Cells; Breast; Caspase 3; Cells, Cultured; Endodeoxyribonucleases; Epithelial Cells; Female; Genome; Genomic Instability; Humans; Mice; Neoplasms, Experimental; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2015 |
Chemopreventive efficacy of menthol on carcinogen-induced cutaneous carcinoma through inhibition of inflammation and oxidative stress in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Anticarcinogenic Agents; Carcinogens; Carcinoma; Chemoprevention; Cyclooxygenase 2; Dermatitis; Female; Glutathione; Inflammation; Menthol; Mice, Inbred ICR; Neoplasms, Experimental; Oxidative Stress; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2015 |
Mitochondrial uncoupling links lipid catabolism to Akt inhibition and resistance to tumorigenesis.
Topics: Animals; Carcinogenesis; Carcinogens; Cell Proliferation; Flow Cytometry; Gene Ontology; Humans; Immunoblotting; Ion Channels; Keratinocytes; Lipid Metabolism; Metabolome; Metabolomics; Mice; Mice, Transgenic; Mitochondria; Mitochondrial Proteins; Neoplasms, Experimental; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Skin Neoplasms; Tetradecanoylphorbol Acetate; Uncoupling Protein 3 | 2015 |
Lgr4 is crucial for skin carcinogenesis by regulating MEK/ERK and Wnt/β-catenin signaling pathways.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Cyclin D1; Extracellular Signal-Regulated MAP Kinases; Genetic Predisposition to Disease; Humans; Keratinocytes; MAP Kinase Kinase 1; Mice, Knockout; Neoplasms, Experimental; Papilloma; Phenotype; Receptors, G-Protein-Coupled; RNA Interference; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Transcription Factor AP-1; Transfection; Wnt Signaling Pathway | 2016 |
A novel protein fraction from Sesbania grandiflora shows potential anticancer and chemopreventive efficacy, in vitro and in vivo.
Topics: Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Caspases; Cell Line; Cell Line, Tumor; Cell Proliferation; Cytochromes c; Enzyme Activation; Flowers; Humans; Male; Mice; Neoplasms; Neoplasms, Experimental; NF-kappa B; Phytotherapy; Plant Extracts; Plant Proteins; Plants, Medicinal; Poly(ADP-ribose) Polymerases; Sesbania; Tetradecanoylphorbol Acetate; Treatment Outcome | 2010 |
SirT1-null mice develop tumors at normal rates but are poorly protected by resveratrol.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Angiogenesis Inhibitors; Animals; Blood Vessels; Carcinogens; Cell Transformation, Neoplastic; Female; Genotype; Immunohistochemistry; Intestinal Polyps; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Knockout; Neoplasms, Experimental; NIH 3T3 Cells; Resveratrol; Sirtuin 1; Sirtuins; Skin Neoplasms; Stilbenes; Tetradecanoylphorbol Acetate; Transfection | 2009 |
Relative inhibitory activity of bile acids against 12-O-tetradecanoylphorbol-13-acetate-induced inflammation, and chenodeoxycholic acid inhibition of tumour promotion in mouse skin two-stage carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anti-Inflammatory Agents; Anticarcinogenic Agents; Bile Acids and Salts; Carcinogens; Chenodeoxycholic Acid; Disease Models, Animal; Edema; Female; Indomethacin; Inflammation; Inhibitory Concentration 50; Mice; Mice, Inbred ICR; Neoplasms, Experimental; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 2009 |
Inhibitory effect of magnolol on TPA-induced skin inflammation and tumor promotion in mice.
Topics: Animals; Base Sequence; Biphenyl Compounds; Carcinogens; Dermatitis, Contact; DNA Primers; Electrophoretic Mobility Shift Assay; Lignans; Mice; Neoplasms, Experimental; Reverse Transcriptase Polymerase Chain Reaction; Tetradecanoylphorbol Acetate | 2010 |
AP1 factor inactivation in the suprabasal epidermis causes increased epidermal hyperproliferation and hyperkeratosis but reduced carcinogen-dependent tumor formation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Base Sequence; Carcinogens; Cell Proliferation; DNA Primers; Epidermis; Mice; Mice, Transgenic; Neoplasms, Experimental; Polymerase Chain Reaction; Skin Diseases; Tetradecanoylphorbol Acetate; Transcription Factor AP-1 | 2010 |
Novel functions for mda-7/IL-24 and IL-24 delE5: regulation of differentiation of acute myeloid leukemic cells.
Topics: Acute Disease; Alternative Splicing; Animals; Blotting, Western; Cell Differentiation; Enzyme Activation; Gene Expression Regulation, Neoplastic; HL-60 Cells; Humans; Interleukins; Leukemia, Myeloid; Mice; Mice, Nude; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neoplasms, Experimental; Protein Isoforms; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Tetradecanoylphorbol Acetate; Transplantation, Heterologous; Tumor Burden; U937 Cells | 2011 |
The arcuate nucleus and neuropeptide Y contribute to the antitumorigenic effect of calorie restriction.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Appetite; Arcuate Nucleus of Hypothalamus; Caloric Restriction; Female; Hunger; Male; Mice; Mice, Knockout; Neoplasms, Experimental; Neurons; Neuropeptide Y; Papilloma; RNA, Messenger; Skin Neoplasms; Sodium Glutamate; Tetradecanoylphorbol Acetate | 2011 |
Miz1 is a critical repressor of cdkn1a during skin tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Differentiation; Cell Proliferation; Cell Transformation, Neoplastic; Cyclin-Dependent Kinase Inhibitor p15; Cyclin-Dependent Kinase Inhibitor p21; Mice; Mice, Transgenic; Neoplasms, Experimental; Nuclear Proteins; Protein Inhibitors of Activated STAT; Protein Structure, Tertiary; Skin Neoplasms; Tetradecanoylphorbol Acetate; Ubiquitin-Protein Ligases | 2012 |
Sindbis viral vectors target hematopoietic malignant cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Female; Gene Expression Regulation, Neoplastic; Genetic Therapy; Genetic Vectors; Hematologic Neoplasms; Humans; Injections, Intraperitoneal; Jurkat Cells; Male; Mice; Mice, Inbred AKR; Mice, Inbred C3H; Mice, Transgenic; Neoplasm Metastasis; Neoplasms, Experimental; Oncolytic Virotherapy; Receptors, Laminin; Sindbis Virus; Tetradecanoylphorbol Acetate | 2012 |
Protection against human papillomavirus type 16-E7 oncogene-induced tumorigenesis by in vivo expression of dominant-negative c-jun.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Genes, Dominant; Genes, jun; Mice; Mice, Transgenic; Neoplasms, Experimental; Oncogene Proteins, Viral; Papillomaviridae; Papillomavirus E7 Proteins; Tetradecanoylphorbol Acetate | 2002 |
Expression of the TGF-beta coreceptor endoglin in epidermal keratinocytes and its dual role in multistage mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, CD; Carcinoma; Cells, Cultured; Endoglin; Epidermal Cells; Epidermis; Humans; Keratinocytes; Mice; Mice, Mutant Strains; Neoplasms, Experimental; Papilloma; Receptors, Cell Surface; Reference Values; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta; Vascular Cell Adhesion Molecule-1 | 2003 |
The carcinogenic potential of extractable organic matter from urban airborne particles in Shanghai, China.
Topics: 3T3 Cells; Air Pollutants; Air Pollution; Animals; Biotransformation; Carcinogens; Cell Survival; China; Cricetinae; DNA Adducts; Female; Fibroblasts; Male; Mesocricetus; Mice; Mice, Inbred BALB C; Mutagenicity Tests; Mutagens; Neoplasms, Experimental; Occupational Exposure; Organic Chemicals; Phosphorus Radioisotopes; Polycyclic Compounds; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2003 |
RasGRP1 represents a novel non-protein kinase C phorbol ester signaling pathway in mouse epidermal keratinocytes.
Topics: Animals; Annexin A5; Apoptosis; Blotting, Western; Cell Differentiation; Cells, Cultured; DNA-Binding Proteins; Dose-Response Relationship, Drug; Down-Regulation; Epidermal Cells; Epidermis; Flow Cytometry; Guanine Nucleotide Exchange Factors; Guanosine Triphosphate; Immunoblotting; Keratin-10; Keratinocytes; Keratins; Mice; Neoplasms, Experimental; Phorbol Esters; Precipitin Tests; Protein Kinase C; Protein Transport; Rats; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2003 |
Inhibition of AP-1 and neoplastic transformation by fresh apple peel extract.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Division; Cell Line; Cell Transformation, Neoplastic; Electron Spin Resonance Spectroscopy; Genes, Reporter; Hydrogen Peroxide; Hydroxyl Radical; Luciferases; Malus; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neoplasms, Experimental; Phosphorylation; Plant Extracts; Reactive Oxygen Species; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate; Time Factors; Transcription Factor AP-1; Transcriptional Activation; Transgenes; Ultraviolet Rays | 2004 |
Deregulated minichromosomal maintenance protein MCM7 contributes to oncogene driven tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biomarkers, Tumor; Carcinogens; Carcinoma, Squamous Cell; Cell Cycle Proteins; Cell Proliferation; Cell Transformation, Neoplastic; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; Genes, ras; Humans; Mice; Mice, Transgenic; Minichromosome Maintenance Complex Component 7; Mutation; Neoplasm Proteins; Neoplasms, Experimental; Nuclear Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2006 |
Cytoplasmic domain phosphorylation of heparin-binding EGF-like growth factor.
Topics: Alanine; Amino Acid Sequence; Animals; Anisomycin; Cell Line; Chlorocebus aethiops; Cytoplasm; Epidermal Growth Factor; Gene Expression Regulation; Heparin-binding EGF-like Growth Factor; Intercellular Signaling Peptides and Proteins; Ionophores; Lysophospholipids; Male; Mice; Mice, Nude; Molecular Sequence Data; Mutation; Neoplasms, Experimental; Peptide Fragments; Phosphorylation; Protein Structure, Tertiary; Serine; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha; Vero Cells | 2006 |
[The establishment of B(a)P and TPA transformed cell line and its biological characteristics].
Topics: Benzo(a)pyrene; Carcinogens; Carcinoma, Squamous Cell; Cell Line; Cell Line, Transformed; Cell Line, Tumor; Cell Transformation, Viral; Cells, Cultured; Epithelial Cells; Humans; Mouth Neoplasms; Neoplasms, Experimental; Tetradecanoylphorbol Acetate; Vimentin | 2006 |
Cancer chemopreventive activity of lupane- and oleanane-type triterpenoids from the cones of Liquidamber styraciflua.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogens; Cell Line; Chromatography, Gel; Humans; Liquidambar; Mice; Neoplasms, Experimental; Oleanolic Acid; Tetradecanoylphorbol Acetate; Triterpenes | 2005 |
Use of IC tags in short-term carcinogenicity study on CB6F1 TGrasH2 mice.
Topics: Acetone; Animal Identification Systems; Animals; Carcinogenicity Tests; Carcinogens; Disease Models, Animal; Female; Genes, ras; Male; Materials Testing; Methylnitrosourea; Mice; Mice, Transgenic; Neoplasms, Experimental; Tetradecanoylphorbol Acetate | 2006 |
Design, semisynthesis, and evaluation of O-acyl derivatives of (-)-epigallocatechin-3-gallate as antitumor agents.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acylation; Animals; Antineoplastic Agents, Phytogenic; Catechin; Mice; Neoplasms, Experimental; Tea; Tetradecanoylphorbol Acetate | 2007 |
Inhibitory effect of the rhizomes of Alpinia officinarum on TPA-induced inflammation and tumor promotion in two-stage carcinogenesis in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alpinia; Animals; Anti-Inflammatory Agents; Anticarcinogenic Agents; Carcinogens; Diarylheptanoids; Female; Inflammation; Inhibitory Concentration 50; Mice; Mice, Inbred ICR; Neoplasms, Experimental; Plant Extracts; Rhizome; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2008 |
Effects of chemical inducers on the Epstein-Barr virus cycle in epithelial/nasopharyngeal carcinoma hybrid cell line.
Topics: Butyrates; Cell Line; Herpesvirus 4, Human; Humans; Hydrogen Peroxide; Nasopharyngeal Neoplasms; Neoplasms, Experimental; Phorbols; Tetradecanoylphorbol Acetate | 1984 |
A cell culture assay for tumor-promoter-dependent progression toward neoplastic phenotype: detection of tumor promoters and promotion inhibitors.
Topics: Animals; Antineoplastic Agents; Carcinogens; Cell Line; Cells, Cultured; Detergents; Epidermal Cells; Mice; Neoplasms, Experimental; Phenotype; Smoking; Tetradecanoylphorbol Acetate | 1980 |
Chemical carcinogenesis by the two-stage protocol in the skin Mastomys natalensis (Muridae) using topical initiation with 7,12-dimethylbenz(a)anthracene and topical promotion with 12-0-tetradecanoylphorbol-13-acetate.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Female; Keratoacanthoma; Male; Muridae; Neoplasms, Experimental; Phorbols; Skin Diseases; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1981 |
The study of tumor promotion in a cell culture model for mouse skin--a tissue that exhibits multistage carcinogenesis in vivo.
Topics: Animals; Carcinogens; Cell Differentiation; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Clone Cells; Cocarcinogenesis; Enzyme Induction; Epidermis; gamma-Glutamyltransferase; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1982 |
Enhancement of viral gene expression in Friend erythroleukemic cells by 12-O tetradecanoylphorbol-13-acetate.
Topics: Cell Differentiation; Clone Cells; Dimethyl Sulfoxide; Friend murine leukemia virus; Genes, Viral; Leukemia, Erythroblastic, Acute; Neoplasms, Experimental; Phorbols; Plasminogen Activators; RNA-Directed DNA Polymerase; RNA, Viral; Tetradecanoylphorbol Acetate | 1980 |
Interferon inhibits melanogenesis in B-16 mouse melanoma cells.
Topics: Animals; Cell Differentiation; Clone Cells; Interferons; Melanins; Melanocyte-Stimulating Hormones; Melanoma; Mice; Monophenol Monooxygenase; Neoplasms, Experimental; Tetradecanoylphorbol Acetate | 1981 |
Effects of 3-isobutyl-1-methylxanthine and cyclic nucleotides on the biochemical processes linked to skin tumor promotion by 12-O-tetradecanoylphorbol-13-acetate.
Topics: 1-Methyl-3-isobutylxanthine; Administration, Topical; Animals; Cocarcinogenesis; Cyclic AMP; Cyclic GMP; DNA, Neoplasm; Dose-Response Relationship, Drug; Female; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Papilloma; Phorbols; Skin Neoplasms; Tetradecanoylphorbol Acetate; Theophylline | 1981 |
Keratin modifications in epidermis, papillomas, and carcinomas during two-stage carcinogenesis in the SENCAR mouse.
Topics: Animals; Carcinogens; Carcinoma; Female; Keratins; Mice; Mice, Inbred Strains; Molecular Weight; Neoplasms, Experimental; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1982 |
Simultaneous appearance of keratin modifications and gamma-glutamyltransferase activity as indicators of tumor progression in mouse skin papillomas.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acyltransferases; Animals; Carcinoma, Squamous Cell; Female; Histocytochemistry; Keratins; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transglutaminases | 1983 |
Translation of lymphocyte mRNA for mouse colony stimulating factor.
Topics: Animals; Cell Line; Colony-Stimulating Factors; Lymphocyte Activation; Lymphocytes; Lymphoma; Mice; Neoplasms, Experimental; Phorbols; Poly A; Protein Biosynthesis; RNA; RNA, Messenger; Tetradecanoylphorbol Acetate | 1983 |
"Dark cells" in normal, hyperplastic, and promoter-treated mouse epidermis studied by conventional and high-voltage electron microscopy.
Topics: Aging; Animals; Epidermal Cells; Epidermis; Female; Hyperplasia; Mice; Microscopy, Electron; Neoplasms, Experimental; Phorbols; Pregnancy; Staining and Labeling; Tetradecanoylphorbol Acetate | 1983 |
K562 cells induced to differentiate by phorbol ester tumor promotors resist NK lysis.
Topics: Cell Differentiation; Cells, Cultured; Humans; Immunity, Innate; Interferons; Killer Cells, Natural; Neoplasm Proteins; Neoplasms, Experimental; Phorbol Esters; Phorbols; RNA, Messenger; Tetradecanoylphorbol Acetate | 1984 |
Modulation of skin tumor promotion by inhibitors of arachidonic acid metabolism.
Topics: Animals; Anti-Inflammatory Agents; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Cell Line; Cricetinae; Cricetulus; Cyclooxygenase Inhibitors; Lipoxygenase Inhibitors; Lung; Mice; Neoplasms, Experimental; Phospholipases A; Prostaglandins; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1983 |
Inhibition by prostaglandin synthesis inhibitors of the induction of epidermal ornithine decarboxylase activity, the accumulation of prostaglandins, and tumor promotion caused by 12-O-tetradecanoylphorbol-13-acetate.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Carboxy-Lyases; Cyclooxygenase Inhibitors; Female; Indomethacin; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Phorbols; Prostaglandins; Prostaglandins E, Synthetic; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin | 1980 |
Suppression of cyclic AMP-dependent protein kinase activity in murine melanoma cells by 12-0-tetradecanoylphorbol-13-acetate.
Topics: Animals; Cells, Cultured; Cyclic AMP; Kinetics; Melanins; Melanoma; Mice; Neoplasms, Experimental; Phorbols; Protein Kinase Inhibitors; Saccharin; Tetradecanoylphorbol Acetate | 1980 |
Enhancement of melanotic expression in cultured mouse melanoma cells by retinoids.
Topics: Animals; Cell Division; Cells, Cultured; Cyclic AMP; Enzyme Activation; Melanins; Melanocyte-Stimulating Hormones; Melanoma; Mice; Monophenol Monooxygenase; Neoplasms, Experimental; Tetradecanoylphorbol Acetate; Tretinoin | 1981 |
Inhibition of epidermal growth factor binding to mouse embryonal carcinoma cells by phorbol esters mediated by specific phorbol ester receptors.
Topics: Animals; Caenorhabditis elegans Proteins; Carcinogens; Carrier Proteins; Cell Line; Epidermal Growth Factor; ErbB Receptors; Kinetics; Mice; Neoplasms, Experimental; Peptides; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Kinase C; Receptors, Cell Surface; Receptors, Drug; Teratoma; Tetradecanoylphorbol Acetate | 1981 |
A clinically relevant canine lung cancer model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Delayed-Action Preparations; Disease Models, Animal; Dogs; Lung Neoplasms; Methods; Methylcholanthrene; Methylnitrosourea; Neoplasms, Experimental; Radioisotopes; Tetradecanoylphorbol Acetate | 1981 |
Phorbol myristate acetate uncouples the relationship between beta-adrenergic receptors and adenyl cyclase in mouse epidermis: a phenotypic trait in papillomas.
Topics: Adenylyl Cyclases; Animals; Cocarcinogenesis; Cyclic GMP; Enzyme Activation; Epidermis; Isoproterenol; Mice; Neoplasms, Experimental; Papilloma; Phorbols; Receptors, Adrenergic; Receptors, Adrenergic, beta; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1982 |
Alterations of glial tumor cell Ca2+ metabolism and Ca2+-dependent cAMP accumulation by phorbol myristate acetate.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Animals; Biological Transport, Active; Calcium; Cell Line; Cholera Toxin; Cyclic AMP; Glioma; Kinetics; Neoplasms, Experimental; Norepinephrine; Phorbols; Rats; Tetradecanoylphorbol Acetate; Trifluoperazine | 1982 |
Changes in the expression of Fc receptor produced by induction of Epstein-Barr virus in lymphoma cell lines.
Topics: Animals; Antigens, Viral; Butyrates; Callitrichinae; Cell Line; Cell Transformation, Viral; Flow Cytometry; Herpesvirus 4, Human; Humans; Lymphoma; Neoplasms, Experimental; Receptors, Fc; Tetradecanoylphorbol Acetate; Virus Activation | 1982 |
Differential effects of retinoic acid and 7,8-benzoflavone on the induction of mouse skin tumors by the complete carcinogenesis process and by the initiation-promotion regimen.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; Dose-Response Relationship, Drug; Enzyme Induction; Female; Flavonoids; Injections, Intraperitoneal; Methylcholanthrene; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Papilloma; Phorbols; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin | 1982 |
The presence of p53 transformation-related protein in Ab-MuLV transformed cells is required for their development into lethal tumors in mice.
Topics: Abelson murine leukemia virus; Animals; Cell Line; Cell Transformation, Neoplastic; Cocarcinogenesis; Female; Leukemia Virus, Murine; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Phorbols; Phosphoproteins; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53 | 1983 |
Relationship of benign papillomas to cancer induction in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Benzopyrenes; Dose-Response Relationship, Drug; Mice; Neoplasms, Experimental; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1981 |
Skin tumor promotion: a comparative study of several stocks and strains of mice.
Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Skin Neoplasms; Species Specificity; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1983 |
Expression of transformed morphology and anchorage independent growth of hamster embryo cells.
Topics: Agar; Animals; Benzo(a)pyrene; Benzopyrenes; Cell Adhesion; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cricetinae; Culture Media; Embryo, Mammalian; Neoplasms, Experimental; Teratoma; Tetradecanoylphorbol Acetate | 1983 |
Acceleration of skin tumorigenesis in mice by submandibular and sublingual gland excision.
Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Kinetics; Male; Mice; Neoplasms, Experimental; Skin Neoplasms; Sublingual Gland; Submandibular Gland; Tetradecanoylphorbol Acetate; Time Factors | 1983 |
12-O-tetradecanoyl-phorbol-13-acetate enhancement of the tumorigenic potential of herpes simplex virus type 2 transformed cells.
Topics: Animals; Cell Division; Cell Transformation, Viral; Cocarcinogenesis; Neoplasms, Experimental; Phorbols; Rats; Simplexvirus; Tetradecanoylphorbol Acetate | 1983 |
1 alpha,25-Dihydroxyvitamin D3 markedly enhances chemically-induced transformation in BALB 3T3 cells.
Topics: Animals; Calcitriol; Cell Transformation, Neoplastic; Cells, Cultured; Cytosol; Dose-Response Relationship, Drug; Methylcholanthrene; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Protein Binding; Receptors, Calcitriol; Receptors, Steroid; Tetradecanoylphorbol Acetate | 1983 |
Differentiation of human myeloid leukemia cell lines induced by tumor-promoting phorbol ester (TPA). I. Changes of the morphology, cytochemistry and the surface differentiation antigens analyzed with monoclonal antibodies.
Topics: Acid Phosphatase; Antibodies, Monoclonal; Antigens, Neoplasm; Carboxylic Ester Hydrolases; Cell Differentiation; Cell Line; Fluorescent Antibody Technique; Histocompatibility Antigens Class II; Histocytochemistry; HLA Antigens; HLA-A Antigens; HLA-DR Antigens; Humans; Leukemia, Myeloid; Lymphoma, Large B-Cell, Diffuse; Naphthol AS D Esterase; Neoplasms, Experimental; Tetradecanoylphorbol Acetate | 1983 |
Effect of the promoter 12-O-tetradecanoylphorbol-13-acetate on the evolution of carcinogen-altered cell populations in tracheas initiated with 7,12-dimethylbenz(a)anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Cell Division; Female; Neoplasms, Experimental; Phorbols; Rats; Rats, Inbred F344; Tetradecanoylphorbol Acetate; Tracheal Neoplasms | 1983 |
Nature of the epidermal hyperplasia produced by mezerein, a weak tumor promoter, in initiated skin of mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Diterpenes; Female; Hyperplasia; Mice; Neoplasms, Experimental; Phorbol Esters; Phorbols; Skin; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate | 1983 |
Skin painting studies in Syrian hamsters.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Cricetinae; Dose-Response Relationship, Drug; Female; Male; Melanoma; Mesocricetus; Neoplasms, Experimental; Nicotiana; Papilloma; Plants, Toxic; Sex Factors; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1983 |
Inhibition of 7-bromomethylbenz[a]anthracene-promoted mouse skin tumor formation by retinoic acid and dexamethasone.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Cocarcinogenesis; Dexamethasone; Drug Interactions; Enzyme Induction; Female; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin | 1983 |
Transplacental skin tumor initiation of Ha/ICR mice at different fetal ages.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Fetus; Maternal-Fetal Exchange; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Papilloma; Pregnancy; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1983 |
Tumor promotion studies in rat tracheal epithelium.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cells, Cultured; Cocarcinogenesis; Epithelium; Methylnitronitrosoguanidine; Neoplasms, Experimental; Organ Culture Techniques; Rats; Tetradecanoylphorbol Acetate; Trachea; Tracheal Neoplasms | 1983 |
Multiple lymphokine production by a phorbol ester-stimulated mouse thymoma: relationship to cell cycle events.
Topics: Animals; Antibodies, Monoclonal; Antigens, Neoplasm; Antigens, Surface; Cell Cycle; Flow Cytometry; Interferon-gamma; Lymphokines; Mice; Neoplasms, Experimental; Phenotype; Phorbols; Rats; Tetradecanoylphorbol Acetate; Thymoma; Thymus Neoplasms | 1983 |
Inhibition of the promotion phase in two-step carcinogenesis in forestomach epithelium of mice by the aromatic retinoid etretinate.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Carcinogens; Epithelium; Etretinate; Female; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin | 1983 |
Partial purification and characterization of a BCGFII from EL4 culture supernatants.
Topics: Animals; B-Lymphocytes; Cell Line; Cell Transformation, Neoplastic; Chromatography, Gel; Chromatography, Ion Exchange; Growth Substances; Interleukin-4; Isoelectric Focusing; Kinetics; Lymphocyte Activation; Lymphokines; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Tetradecanoylphorbol Acetate | 1984 |
Two-stage tumorigenesis of dermal melanocytes in the back skin of the Syrian golden hamster using systemic initiation with 7,12-dimethylbenz(a)anthracene and topical promotion with 12-O-tetradecanoylphorbol-13-acetate.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Cocarcinogenesis; Cricetinae; Female; Melanocytes; Melanoma; Mesocricetus; Neoplasms, Experimental; Phorbols; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1980 |
Characteristics of neoplastic progression and tumor behavior in skin carcinogenesis by different methods: an experimental study.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cocarcinogenesis; Female; Keratoacanthoma; Mice; Neoplasms, Experimental; Papilloma; Precancerous Conditions; Sarcoma, Experimental; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1980 |
Autoantibody and tumor promotion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antibody Formation; Autoantibodies; Croton Oil; Female; Mice; Mice, Inbred A; Neoplasms, Experimental; Phorbols; Tetradecanoylphorbol Acetate | 1980 |
Studies on mechanism of action of anti-tumor-promoting agents: their specificity in two-stage promotion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Diterpenes; Epidermal Cells; Female; Fluocinolone Acetonide; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Phorbol Esters; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate; Tosylphenylalanyl Chloromethyl Ketone; Tretinoin | 1980 |
Studies on the mechanism of skin tumor promotion: evidence for several stages in promotion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Chemical Phenomena; Chemistry; Cocarcinogenesis; Diterpenes; Dose-Response Relationship, Drug; Drug Synergism; Female; Mice; Neoplasms, Experimental; Phorbol Esters; Phorbols; Skin; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate | 1980 |
Promotion-like enhancement of tracheal carcinogenesis in rats by 12-O-tetradecanoylphorbol-13-acetate.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma; Cocarcinogenesis; Dose-Response Relationship, Drug; Neoplasms, Experimental; Phorbols; Rats; Tetradecanoylphorbol Acetate; Tracheal Neoplasms | 1980 |
Protection of mice against 7,12-dimethylbenz(a)anthracene-induced skin tumors by immunization with a fluorinated analog of the carcinogen.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antibody Formation; Benz(a)Anthracenes; Cocarcinogenesis; Immunization; Mice; Neoplasms, Experimental; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1981 |
Initiation and promotion at different ages and doses in 2200 mice. I. Methods, and the apparent persistence of initiated cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aging; Animals; Dose-Response Relationship, Drug; Drug Synergism; Female; Mice; Neoplasms, Experimental; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1981 |
Initiation and promotion at different ages and doses in 2200 mice. II. Decrease in promotion by TPA with ageing.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aging; Animals; Dose-Response Relationship, Drug; Drug Synergism; Female; Mice; Neoplasms, Experimental; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1981 |
Initiation and promotion at different ages and doses in 2200 mice. III. Linear extrapolation from high doses may underestimate low-dose tumour risks.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aging; Animals; Dose-Response Relationship, Drug; Drug Synergism; Female; Mice; Neoplasms, Experimental; Risk; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1981 |
Mouse skin cells resistant to terminal differentiation associated with initiation of carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Calcium; Cell Differentiation; Cell Division; Cells, Cultured; Epidermis; Mice; Neoplasms, Experimental; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1981 |
Skin tumor-promoting activity of benzoyl peroxide, a widely used free radical-generating compound.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzoyl Peroxide; Cocarcinogenesis; Free Radicals; Mice; Neoplasms, Experimental; Peroxides; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1981 |
Diaplacental initiation of NMRI mice with 7,12-dimethylbenz[a]anthracene during gestation days 6--20 and postnatal treatment of the F1-generation with the phorbol ester 12-O-tetradecanoylphorbol-13-acetate: tumor incidence in organs other than the skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Carcinogens; Female; Gestational Age; Mice; Neoplasms, Experimental; Phorbols; Pregnancy; Prenatal Exposure Delayed Effects; Sex Factors; Tetradecanoylphorbol Acetate | 1981 |
Sensitivity to two-stage carcinogenesis of SENCAR mouse skin grafted to nude mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cocarcinogenesis; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms, Experimental; Papilloma; Skin; Skin Neoplasms; Skin Transplantation; Species Specificity; Tetradecanoylphorbol Acetate | 1982 |
Glutathione depletion sensitizes tumor cells to oxidative cytolysis.
Topics: Animals; Buthionine Sulfoximine; Cell Survival; Glutathione; Kinetics; Leukemia P388; Mast-Cell Sarcoma; Methionine Sulfoximine; Mice; Neoplasms, Experimental; Tetradecanoylphorbol Acetate | 1982 |
Epidermal tumor promotion by regeneration.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Differentiation; Cell Division; Epidermis; Female; Hyperplasia; Mice; Neoplasms, Experimental; Regeneration; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1982 |
The differential effects of retinoic acid and 7,8-benzoflavone on the induction of mouse skin tumors by the initiation-promotion protocol and by the complete carcinogenesis process.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Benzoflavones; Carcinogens; Cocarcinogenesis; Enzyme Induction; Flavonoids; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Tretinoin | 1982 |
Diterpene ester-mediated two-stage carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cocarcinogenesis; Cricetinae; Female; Guinea Pigs; Male; Maternal-Fetal Exchange; Mice; Mice, Inbred Strains; Milk; Neoplasms, Experimental; Phorbols; Pregnancy; Prenatal Exposure Delayed Effects; Rabbits; Rats; Skin Neoplasms; Tetradecanoylphorbol Acetate; Vaginal Neoplasms | 1982 |
Epidermal-dermal junction during experimental skin carcinogenesis and cocarcinogenesis as revealed by scanning electron microscopy.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cocarcinogenesis; Female; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1982 |
Polyamine biosynthesis and skin tumor promotion: inhibition of 12-O-tetradecanoylphorbol-13-acetate-promoted mouse skin tumor formation by the irreversible inhibitor of ornithine decarboxylase alpha-difluoromethylornithine.
Topics: Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Drug Antagonism; Eflornithine; Kinetics; Mice; Neoplasms, Experimental; Ornithine; Ornithine Decarboxylase Inhibitors; Phorbols; Polyamines; Putrescine; Skin; Skin Neoplasms; Spermidine; Spermine; Tetradecanoylphorbol Acetate | 1982 |
Mouse skin tumor-initiating activity of 5-, 7-, and 12-methyl- and fluorine-substituted benz[a]anthracenes.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Carcinogens; Cocarcinogenesis; Female; Hydrocarbons, Fluorinated; Mice; Neoplasms, Experimental; Papilloma; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Time Factors | 1982 |
7,12-Dimethylbenz[a]anthracene/12-O-tetradecanoyl-phorbol-13-acetate-mediated skin tumor initiation and promotion in male Sprague-Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Carcinogens; Cocarcinogenesis; Diazonium Compounds; Male; Neoplasms, Experimental; Phorbols; Rats; Rats, Inbred Strains; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1982 |
Resistance of A-431 epidermoid carcinoma cells to early membrane changes induced by tumour promoters.
Topics: Arachidonic Acid; Arachidonic Acids; Carcinogens; Carcinoma, Squamous Cell; Cells, Cultured; Choline; Drug Resistance; Humans; Membranes; Neoplasms, Experimental; Phospholipids; Tetradecanoylphorbol Acetate | 1982 |
Stimulation of fibronectin production by retinoic acid in mouse skin tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Chromatography, Affinity; Female; Fibronectins; Fucose; Leucine; Mice; Neoplasms, Experimental; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin | 1982 |
Teleocidin from Streptomyces is a potent promoter of mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alkaloids; Animals; Carcinogens; Female; Lyngbya Toxins; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Skin Neoplasms; Streptomyces; Tetradecanoylphorbol Acetate | 1982 |
Production of immune interferon by an interleukin 2-independent murine T cell line.
Topics: Animals; Cell Line; Interferon-gamma; Interleukin-2; Kinetics; Mice; Neoplasms, Experimental; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymoma; Thymus Neoplasms | 1982 |
Effect of phorbol esters on alloimmune cytolysis.
Topics: Animals; Cell Survival; Cytotoxicity, Immunologic; Lymphoma; Mast-Cell Sarcoma; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Phorbols; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1982 |
Inhibition of 12-O-tetradecanoyl-phorbol-13-acetate-induced tumor promotion by nordihydroguaiaretic acid, a lipoxygenase inhibitor, and p-bromophenacyl bromide, a phospholipase A2 inhibitor.
Topics: Acetophenones; Animals; Catechols; Enzyme Inhibitors; Female; Lipoxygenase Inhibitors; Masoprocol; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Phorbols; Phospholipases; Phospholipases A; Phospholipases A2; Pyrazoles; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1982 |
alpha-Difluoromethylornithine, an irreversible inhibitor of ornithine decarboxylase, inhibits tumor promoter-induced polyamine accumulation and carcinogenesis in mouse skin.
Topics: Alkynes; Animals; Antineoplastic Agents, Phytogenic; Carboxy-Lyases; Carcinogens; Diterpenes; Eflornithine; Female; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Ornithine; Ornithine Decarboxylase Inhibitors; Phorbol Esters; Polyamines; Skin; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate | 1982 |
Tumor promotion by phorbol esters in skin: evidence for a memory effect.
Topics: Animals; Carcinogens; Cell Line; Epidermis; Female; Hyperplasia; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Phorbol Esters; Phorbols; Precancerous Conditions; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1983 |
Effect of retinoic acid on the synthesis of glycoproteins of mouse skin tumors during progression from promoted skin through papillomas to carcinomas.
Topics: Animals; Electrophoresis, Polyacrylamide Gel; Glycoproteins; Male; Mice; Molecular Weight; Neoplasm Proteins; Neoplasms, Experimental; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin | 1983 |
Tumor promoting activity of 1,8-dihydroxy-3-methyl-9-anthrone (chrysarobin) in female SENCAR mice.
Topics: Animals; Anthracenes; Carcinogens; Female; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1983 |
Mouse skin application in chemical carcinogenesis.
Topics: Animals; Biological Assay; Carcinogens; Cocarcinogenesis; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Papilloma; Respiratory Tract Neoplasms; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1983 |
Tumour-initiating activities of dihydrodiols of dibenz[a,c]anthracene.
Topics: Animals; Benz(a)Anthracenes; Female; Mice; Neoplasms, Experimental; Phorbols; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1983 |
Mechanisms of lectin and antibody-dependent polymorphonuclear leukocyte-mediated cytolysis.
Topics: Animals; Antibody-Dependent Cell Cytotoxicity; Cells, Cultured; Cytotoxicity, Immunologic; Deoxyglucose; Glycolysis; Lectins; Male; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Neutrophils; Oxygen; Tetradecanoylphorbol Acetate | 1983 |
Onion and garlic oils inhibit tumor promotion.
Topics: Animals; Cell Transformation, Neoplastic; Drug Antagonism; Female; Garlic; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Oils; Phorbols; Plants, Medicinal; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1983 |
PRomotion of smooth surface tumorigenicity by phorbol myristate acetate in Balb/3T3 cells and Balb/3T3 T proadipocytes.
Topics: Animals; Cell Differentiation; Cell Line; Cocarcinogenesis; Embryo, Mammalian; Mice; Neoplasms, Experimental; Phorbol Esters; Phorbols; Tetradecanoylphorbol Acetate; Time Factors | 1981 |
Effects of tumor-promoting agents on cells of the murine immune system: inhibition of antibody synthesis and of macrophage-mediated tumor cell cytotoxicity.
Topics: Animals; Antibody Formation; B-Lymphocytes; Cytotoxicity, Immunologic; Female; Macrophages; Mice; Neoplasms, Experimental; Phorbol Esters; Phorbols; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1982 |
Human B-lymphocyte maturation sequence revealed by TPA-induced differentiation of leukaemic cells.
Topics: B-Lymphocytes; Cell Differentiation; Cells, Cultured; Humans; Leukemia, Lymphoid; Neoplasms, Experimental; Phorbols; Receptors, Immunologic; Rosette Formation; Tetradecanoylphorbol Acetate | 1982 |
Role of activated macrophages in antibody-dependent lysis of tumor cells.
Topics: Animals; Antibody-Dependent Cell Cytotoxicity; Ascitic Fluid; Female; Hydrogen Peroxide; Immune Sera; Isoantigens; Macrophages; Male; Mice; Microscopy, Electron, Scanning; Mycobacterium bovis; Neoplasms, Experimental; Phagocytosis; Propionibacterium acnes; Receptors, Fc; Tetradecanoylphorbol Acetate; Time Factors | 1980 |
Role of oxygen-dependent mechanisms in antibody-induced lysis of tumor cells by activated macrophages.
Topics: Animals; Antibody-Dependent Cell Cytotoxicity; Cell Line; Cytochalasins; Glucose; Hydrogen Peroxide; Immune Sera; Isoantigens; Macrophages; Mice; Mycobacterium bovis; Neoplasms, Experimental; Oxidation-Reduction; Oxygen; Tetradecanoylphorbol Acetate; Thioglycolates | 1980 |
Epidermal proliferation of nude mouse skin, pig skin, and pig skin grafts. Failure of nude mouse skin to respond to the tumor promoter 12-O-tetradecanoyl phorbol 13-acetate.
Topics: Animals; Mice; Mice, Nude; Neoplasms, Experimental; Phorbols; Skin; Skin Neoplasms; Skin Transplantation; Swine; Tetradecanoylphorbol Acetate; Transplantation Immunology; Transplantation, Heterologous | 1980 |
Suppression of natural tumor resistance by tumor promoters.
Topics: Animals; Cell Line; Cytotoxicity, Immunologic; Lymphokines; Macrophage Activation; Macrophage-Activating Factors; Macrophages; Neoplasms, Experimental; Phorbols; Rats; Tetradecanoylphorbol Acetate | 1982 |
Enhanced transformation of mouse 10T1/2 cells by 12-O-tetradecanoylphorbol-13-acetate following exposure to X-rays or to fission-spectrum neutrons.
Topics: Animals; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Cocarcinogenesis; Fast Neutrons; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Neoplasms, Radiation-Induced; Neutrons; Phorbols; Radiation Dosage; Tetradecanoylphorbol Acetate; X-Rays | 1982 |
Effects of tumor-promoting phorbol diesters on neoplastic progression of Syrian hamster embryo cells.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Cricetinae; Embryo, Mammalian; Mesocricetus; Neoplasms, Experimental; Ornithine Decarboxylase; Phorbol Esters; Phorbols; Polyamines; Precancerous Conditions; Tetradecanoylphorbol Acetate | 1982 |
Application of tumor, bacterial and parasite susceptibility assays to study immune alterations induced by environmental chemicals.
Topics: Animals; Bacterial Infections; Benzopyrenes; Diethylstilbestrol; Endotoxins; Environmental Pollutants; Female; Immunity; Listeriosis; Lung Neoplasms; Male; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Parasitic Diseases; Tetradecanoylphorbol Acetate; Trichinellosis | 1982 |
Simple phorbol esters as inhibitors of tumor promotion by TPA in mouse skin.
Topics: Animals; Cocarcinogenesis; DNA; Dose-Response Relationship, Drug; Epidermis; Female; Hyperplasia; Mice; Neoplasms, Experimental; Phorbol Esters; Phorbols; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1982 |
Tumor-initiating ability of the twelve monomethylbenz[a]anthracenes.
Topics: Animals; Benz(a)Anthracenes; Carcinogens; Cocarcinogenesis; Dose-Response Relationship, Drug; Female; Mice; Neoplasms, Experimental; Papilloma; Tetradecanoylphorbol Acetate | 1982 |
Retinoids and inhibition of ornithine decarboxylase activity.
Topics: Animals; Carboxy-Lyases; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin | 1982 |
Enhancement of sister-chromatid exchanges by tumour promoters.
Topics: Animals; Cell Cycle; Cell Line; Crossing Over, Genetic; Deoxyglucose; Dose-Response Relationship, Drug; Neoplasms, Experimental; Phenobarbital; Phorbols; Saccharin; Sister Chromatid Exchange; Tetradecanoylphorbol Acetate | 1982 |
Suppression of the cytotoxic response of mouse lymphocytes to syngeneic tumor cells by tumor-promoting phorbol ester.
Topics: Animals; Cell Line; Cytotoxicity, Immunologic; Female; Killer Cells, Natural; Lymphoma; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Multiple Myeloma; Neoplasms, Experimental; Phorbols; Tetradecanoylphorbol Acetate | 1982 |
Decrease in cytosolic calcium/phospholipid-dependent protein kinase activity following phorbol ester treatment of EL4 thymoma cells.
Topics: Animals; Calcium; Cell Line; Mice; Neoplasms, Experimental; Phorbol Esters; Phorbols; Phospholipids; Protein Kinases; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Thymoma; Thymus Neoplasms | 1982 |
Inhibition of mouse skin tumor promotion by several inhibitors of arachidonic acid metabolism.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Acetophenones; Animals; Arachidonic Acids; Biotransformation; Female; Male; Mice; Neoplasms, Experimental; Oxygenases; Papilloma; Phorbols; Phospholipases; Phospholipases A; Phospholipases A2; Prostaglandin Antagonists; Pyrazoles; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1982 |
Effect of tumor promoters on lipid peroxidation in mouse skin.
Topics: Age Factors; Animals; Antineoplastic Agents, Phytogenic; Carcinogens; Diterpenes; Glutathione Peroxidase; Kinetics; Lipid Peroxides; Male; Mice; Neoplasms, Experimental; Phorbol Esters; Skin; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate | 1982 |
Biological effects of phorbol ester tumor promoters in mouse skin.
Topics: Animals; Cell Division; Hyperplasia; Kinetics; Mice; Neoplasms, Experimental; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1982 |
Chemical carcinogenesis studies in mouse epidermal cell cultures.
Topics: Animals; Carcinogens; Cell Differentiation; Cell Transformation, Neoplastic; Cells, Cultured; Environmental Exposure; Enzyme Induction; Epidermal Cells; Epidermis; Methylnitronitrosoguanidine; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin | 1980 |
Tumor cell anti-oxidant defenses. Inhibition of the glutathione redox cycle enhances macrophage-mediated cytolysis.
Topics: Animals; Carmustine; Catalase; Cytotoxicity, Immunologic; Female; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Hydrogen Peroxide; Macrophages; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasms, Experimental; Oxidation-Reduction; Selenium; Tetradecanoylphorbol Acetate | 1981 |
Natural killer cells kill tumour cells at a given stage of differentiation.
Topics: Acetamides; Animals; Butyrates; Cell Differentiation; Cell Line; Cytotoxicity, Immunologic; Diamines; Hemin; Humans; Immunity, Innate; Killer Cells, Natural; Mice; Neoplasms, Experimental; Tetradecanoylphorbol Acetate | 1981 |
The role of anthralin in mouse skin tumour promotion.
Topics: Animals; Anthracenes; Anthralin; DNA; Enzyme Induction; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1981 |
Enhancement of carcinogenesis in cultured respiratory tract epithelium by 12-0-tetradecanoylphorbol-13-acetate.
Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Epithelium; Female; Methylnitronitrosoguanidine; Neoplasms, Experimental; Phorbols; Rats; Tetradecanoylphorbol Acetate; Time Factors; Trachea; Tracheal Neoplasms | 1980 |
Characterization of arginase activity from mouse epidermis and its relation to ornithine decarboxylase induction by the tumor-promoting agent, 12-O-tetradecanoylphorbol-13-acetate.
Topics: Animals; Arginase; Carboxy-Lyases; Enzyme Induction; Female; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Phorbols; Polyamines; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1981 |
Phorbol ester-induced anchorage independence and its antagonism by retinoic acid correlates with altered expression of specific glycoproteins.
Topics: Animals; Carcinogens; Cell Adhesion; Cells, Cultured; Gene Expression Regulation; Glycoproteins; Mice; Neoplasms, Experimental; Phorbols; Tetradecanoylphorbol Acetate; Tretinoin | 1981 |
Retinoic acid analogues with ring modifications. Synthesis and pharmacological activity.
Topics: Animals; Antineoplastic Agents; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Tretinoin | 1981 |
Tumorigenic activity of benzo(e)pyrene derivatives on mouse skin and in newborn mice.
Topics: Animals; Animals, Newborn; Benzopyrenes; Biotransformation; Dihydroxydihydrobenzopyrenes; Female; Liver Neoplasms; Lung Neoplasms; Male; Mice; Neoplasms, Experimental; Papilloma; Pregnancy; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1980 |
Structure-activity relationships in chick embryo fibroblasts for phorbol-related diterpene esters showing anomalous activities in vivo.
Topics: Animals; Cells, Cultured; Chick Embryo; Deoxy Sugars; Deoxyglucose; Fibroblasts; Fibronectins; Inflammation; Mice; Neoplasms, Experimental; Phorbol Esters; Phorbols; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1980 |
Carcinogenicity of chloroethylene oxide, an ultimate reactive metabolite of vinyl chloride, and bis(chloromethyl)ether after subcutaneous administration and in initiation-promotion experiments in mice.
Topics: Animals; Bis(Chloromethyl) Ether; Ethylene Oxide; Female; Male; Methyl Ethers; Mice; Mutagens; Neoplasms, Experimental; Papilloma; Skin Neoplasms; Soft Tissue Neoplasms; Tetradecanoylphorbol Acetate; Vinyl Chloride | 1980 |
Comparative tumor-initiating activity of methylated benzo(a)pyrene derivatives in mouse skin.
Topics: Animals; Benzopyrenes; Cocarcinogenesis; Female; Methylation; Mice; Neoplasms, Experimental; Papilloma; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1980 |
Prostaglandin enhancement of skin tumor initiation and promotion.
Topics: Animals; Indomethacin; Mice; Neoplasms, Experimental; Phorbols; Prostaglandins; Prostaglandins E; Prostaglandins F; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1980 |
Retinoic acid analogues. Synthesis and potential as cancer chemopreventive agents.
Topics: Animals; Epidermis; Female; Mice; Neoplasms; Neoplasms, Experimental; Ornithine Decarboxylase Inhibitors; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Tretinoin | 1980 |
An organ culture of adult mouse skin: an in vitro model for studying the molecular mechanism of skin tumor promotion.
Topics: Animals; Carboxy-Lyases; DNA; Enzyme Induction; Female; Indomethacin; Mice; Models, Biological; Neoplasms, Experimental; Organ Culture Techniques; Ornithine Decarboxylase; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin | 1980 |
A human melanoma cell line established from xenograft in athymic mice.
Topics: Animals; Cell Division; Cell Line; Dimethyl Sulfoxide; Humans; Isoenzymes; Karyotyping; Melanins; Melanoma; Mice; Mice, Nude; Microscopy, Electron; Neoplasm Transplantation; Neoplasms, Experimental; Tetradecanoylphorbol Acetate; Transplantation, Heterologous | 1980 |
Indomethacin enhancement of TPA tumor promotion in mice.
Topics: Animals; Drug Synergism; Female; Flurbiprofen; Indomethacin; Mice; Neoplasms, Experimental; Papilloma; Phorbols; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1980 |
Paradoxical effect of anthralin on 12-O-tetradecanoylphorbol-13-acetate-induced mouse epidermal ornithine decarboxylase activity, proliferation, and tumor promotion.
Topics: Animals; Anthracenes; Anthralin; Carboxy-Lyases; Cell Division; Enzyme Induction; Epidermal Cells; Epidermis; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1981 |
In vitro induction of ornithine decarboxylase in urinary bladder carcinoma cells.
Topics: Animals; Carboxy-Lyases; Carcinogens; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Cell Line; Cocarcinogenesis; Enzyme Induction; Neoplasms, Experimental; Ornithine Decarboxylase; Rats; Tetradecanoylphorbol Acetate; Urinary Bladder Neoplasms; Urine | 1981 |
Exceptionally high tumor-initiating activity of benzo(c)phenanthrene bay-region diol-epoxides on mouse skin.
Topics: Animals; Carcinogens; Cocarcinogenesis; Mice; Neoplasms, Experimental; Phenanthrenes; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1980 |
The important role of PKC in controlling polyploidy formation in cultured fibrosarcoma cell line.
Topics: Adenosine Triphosphate; Animals; Cell Division; Demecolcine; Enzyme Activation; Fibrosarcoma; Methylcholanthrene; Mice; Mice, Inbred BALB C; Mitosis; Neoplasms, Experimental; Polyploidy; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Rotenoids mediate potent cancer chemopreventive activity through transcriptional regulation of ornithine decarboxylase.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents, Phytogenic; Cell Differentiation; Cells, Cultured; Female; Gene Expression Regulation, Enzymologic; HL-60 Cells; Humans; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Organ Culture Techniques; Ornithine Decarboxylase; Precancerous Conditions; Protein Kinase C; RNA, Messenger; Rotenone; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1995 |
Adult T cell leukemia-derived factor/human thioredoxin protects endothelial F-2 cell injury caused by activated neutrophils or hydrogen peroxide.
Topics: Animals; Cell Death; Cell Line; Cell Survival; Cells, Cultured; Cytokines; Dose-Response Relationship, Drug; Endothelium; Humans; Hydrogen Peroxide; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Nude; Neoplasm Proteins; Neoplasms, Experimental; Neutrophils; Oxidative Stress; Recombinant Proteins; Tetradecanoylphorbol Acetate; Thioredoxins | 1994 |
Putative role of antioxidant enzymes and glyoxalases in carcinogenesis.
Topics: Animals; DDT; Depression, Chemical; Estradiol; Female; Lactoylglutathione Lyase; Liver; Neoplasms, Experimental; Oxidoreductases; Phenobarbital; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate; Thiolester Hydrolases | 1993 |
Overexpression of protein kinase C-delta and -epsilon in NIH 3T3 cells induces opposite effects on growth, morphology, anchorage dependence, and tumorigenicity.
Topics: 3T3 Cells; Animals; Biological Transport; Blotting, Northern; Blotting, Western; Brain; Cell Adhesion; Cell Division; Cell Transformation, Neoplastic; Cloning, Molecular; Enzyme Activation; Enzyme Stability; Indoles; Isoenzymes; Kinetics; Maleimides; Mice; Mice, Inbred C57BL; Mice, Nude; Neoplasms, Experimental; Protein Kinase C; Tetradecanoylphorbol Acetate | 1993 |
Role of protein kinase C and cytokines on the function and production of cytolytic granules in alpha CD3-activated killer-cell-mediated killing of tumor cells.
Topics: Alkaloids; Animals; Antibodies; Antibody-Dependent Cell Cytotoxicity; CD3 Complex; Cytokines; Cytoplasmic Granules; Cytotoxicity, Immunologic; Female; Granzymes; Immunotherapy, Adoptive; Killer Cells, Natural; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Protein Kinase C; Serine Endopeptidases; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
The preventive and therapeutic potential of the squalene-containing compound, Roidex, on tumor promotion and regression.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aloe; Animals; Carcinogens; Drug Combinations; Drug Screening Assays, Antitumor; Female; Mice; Mineral Oil; Neoplasms, Experimental; Plants, Medicinal; Remission Induction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Vitamin A; Vitamin E | 1996 |
[Skin carcinogenesis induced be neonatal administration of 5-bromo-2'-deoxyuridine and subsequent treatment with 12-O-tetradecanoylphorbol-13-acetate in mice].
Topics: Animals; Bromodeoxyuridine; Carcinogens; Female; Male; Mice; Mice, Hairless; Neoplasms, Experimental; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1996 |
Effect of peritoneal cells on tumors cells growth in vitro.
Topics: Animals; Cell Adhesion; Cell Division; Immunosuppressive Agents; Immunotherapy, Adoptive; Killer Cells, Natural; Leukemia P388; Lymphoma; Macrophage Activation; Macrophages; Male; Mast-Cell Sarcoma; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Peritoneal Cavity; Respiratory Burst; Superoxides; Terpenes; Tetradecanoylphorbol Acetate | 1995 |
Inhibitory effect of pheophorbide a, a chlorophyll-related compound, on skin tumor promotion in ICR mouse.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogens; Chlorophyll; Drug Screening Assays, Antitumor; Female; Mice; Mice, Inbred ICR; Neoplasms, Experimental; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1996 |
Inhibitory effects of topical application of low doses of curcumin on 12-O-tetradecanoylphorbol-13-acetate-induced tumor promotion and oxidized DNA bases in mouse epidermis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Antineoplastic Agents; Carcinogens; Curcumin; DNA; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; HeLa Cells; Humans; Mice; Neoplasms, Experimental; Oxidation-Reduction; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1997 |
Overexpression of insulin-like growth factor-1 induces hyperplasia, dermal abnormalities, and spontaneous tumor formation in transgenic mice.
Topics: Animals; Carcinogens; Epidermis; Fluorescent Antibody Technique, Indirect; Humans; Hyperplasia; Insulin-Like Growth Factor I; Keratins; Mice; Mice, Transgenic; Neoplasms, Experimental; Skin Abnormalities; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1997 |
Use of E mu-PIM-1 transgenic mice short-term in vivo carcinogenicity testing: lymphoma induction by benzo[a]pyrene, but not by TPA.
Topics: Animals; Benzo(a)pyrene; Body Weight; Carcinogens; Enhancer Elements, Genetic; Female; Gene Expression Regulation, Neoplastic; Genes, myc; Immunoglobulin mu-Chains; Lymphoma; Male; Mice; Mice, Transgenic; Neoplasms, Experimental; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-pim-1; Stomach Neoplasms; Tetradecanoylphorbol Acetate | 1997 |
Ca2+ and protein kinase C-dependent mechanisms involved in gastrin-induced Shc/Grb2 complex formation and P44-mitogen-activated protein kinase activation.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Animals; Blotting, Western; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Activation; Gastrins; GRB2 Adaptor Protein; Humans; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neoplasms, Experimental; Phosphorylation; Protein Kinase C; Proteins; Rats; Shc Signaling Adaptor Proteins; Signal Transduction; Src Homology 2 Domain-Containing, Transforming Protein 1; Tetradecanoylphorbol Acetate; Thapsigargin; Tumor Cells, Cultured; Tyrosine | 1997 |
The DNA repair protein O6-methylguanine-DNA methyltransferase protects against skin tumor formation induced by antineoplastic chloroethylnitrosourea.
Topics: Animals; Antineoplastic Agents, Alkylating; DNA Mutational Analysis; Genes, ras; Humans; Methyltransferases; Mice; Mice, Transgenic; Neoplasms, Experimental; Nimustine; O(6)-Methylguanine-DNA Methyltransferase; Papilloma; Point Mutation; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1997 |
Evidence that cutaneous carcinogen-initiated epithelial cells from mice are quiescent rather than actively cycling.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Antimetabolites, Antineoplastic; Carcinogens; Cell Division; Epidermis; Female; Fluorouracil; Hair Follicle; Mice; Neoplasms, Experimental; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1997 |
Protein kinase C-alpha activity inversely modulates invasion and growth of intestinal cells.
Topics: Animals; Cadherins; Carbazoles; Cell Adhesion; Cell Movement; Cell Size; Gene Expression Regulation, Neoplastic; Humans; Indoles; Maleimides; Mice; Mice, Nude; Mutagenesis, Site-Directed; Neoplasm Invasiveness; Neoplasms, Experimental; Protein Kinase C; Tetradecanoylphorbol Acetate; Transfection; Transplantation, Heterologous; Tumor Cells, Cultured; Urokinase-Type Plasminogen Activator | 1998 |
Potent suppressive activity of pheophytin a and b from the non-polyphenolic fraction of green tea (Camellia sinensis) against tumor promotion in mouse skin.
Topics: 3T3 Cells; 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Dose-Response Relationship, Drug; Edema; Female; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Ornithine Decarboxylase; Pheophytins; Skin; Skin Neoplasms; Tea; Tetradecanoylphorbol Acetate | 1998 |
Suppression of mouse skin tumor promotion and induction of apoptosis in HL-60 cells by Alpinia oxyphylla Miquel (Zingiberaceae).
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinogens; DNA Fragmentation; DNA, Neoplasm; Drug Screening Assays, Antitumor; Female; HL-60 Cells; Humans; Mice; Mice, Inbred ICR; Neoplasms, Experimental; Phytotherapy; Skin Neoplasms; Tetradecanoylphorbol Acetate; Zingiberales | 1998 |
Isoflavone genistein inhibits the initiation and promotion of two-stage skin carcinogenesis in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Carcinogens; DNA Adducts; Down-Regulation; Drug Screening Assays, Antitumor; Female; Genistein; Hydrogen Peroxide; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Peroxidase; Protein-Tyrosine Kinases; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1998 |
Inhibitory effect of Hesperidin on tumour initiation and promotion in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Cutaneous; Animals; Antineoplastic Agents; Carcinogens; Drug Antagonism; Female; Hesperidin; Mice; Neoplasms, Experimental; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1998 |
Inhibition of TPA-induced tumor promotion in CD-1 mouse epidermis by a polyphenolic fraction from grape seeds.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anthocyanins; Carcinogens; Drug Screening Assays, Antitumor; Eflornithine; Enzyme Inhibitors; Female; Flavonoids; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Peroxidase; Phenols; Polymers; Proanthocyanidins; Rosales; Seeds; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1999 |
E2F1 has both oncogenic and tumor-suppressive properties in a transgenic model.
Topics: Animals; Apoptosis; Carrier Proteins; Cell Cycle Proteins; DNA-Binding Proteins; E2F Transcription Factors; E2F1 Transcription Factor; Female; Genes, Tumor Suppressor; Humans; Male; Mice; Mice, Inbred SENCAR; Mice, Transgenic; Neoplasms, Experimental; Oncogenes; Retinoblastoma-Binding Protein 1; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factor DP1; Transcription Factors | 1999 |
Inhibitory effect of euphol, a triterpene alcohol from the roots of Euphorbia kansui, on tumour promotion by 12-O-tetradecanoylphorbol-13-acetate in two-stage carcinogenesis in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Alcohols; Animals; Antihypertensive Agents; Carcinogens; Ear; Female; Inflammation; Lanosterol; Mice; Mice, Inbred ICR; Neoplasms, Experimental; Skin Neoplasms; Tetradecanoylphorbol Acetate; Triterpenes | 2000 |
EBV DNA polymerase inhibition of tannins from Eugenia uniflora.
Topics: Carcinogens; Catechin; Cell Line; DNA-Binding Proteins; DNA-Directed DNA Polymerase; Flavonoids; Humans; Hydrolyzable Tannins; Inhibitory Concentration 50; Neoplasms, Experimental; Nucleic Acid Synthesis Inhibitors; Plant Extracts; Tannins; Tetradecanoylphorbol Acetate; Viral Proteins | 2000 |
Retinoic acid (RA) receptor transcriptional activation correlates with inhibition of 12-O-tetradecanoylphorbol-13-acetate-induced ornithine decarboxylase (ODC) activity by retinoids: a potential role for trans-RA-induced ZBP-89 in ODC inhibition.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Blotting, Northern; Blotting, Western; Carcinogens; Cell Survival; Collagenases; DNA-Binding Proteins; Dose-Response Relationship, Drug; Epidermis; Epithelial Cells; Female; HeLa Cells; Humans; Mice; Mice, Hairless; Neoplasms, Experimental; Ornithine Decarboxylase Inhibitors; Papilloma; Promoter Regions, Genetic; Protein Binding; Protein Kinases; Rats; Receptors, Retinoic Acid; Response Elements; Retinoic Acid Receptor alpha; Retinoic Acid Receptor gamma; Retinoids; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Trachea; Transcription Factor AP-1; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transfection; Ultraviolet Rays | 2001 |
Two-stage carcinogenesis in NMRI mice: intravaginal application of 7,12-dimethylbenz[a]anthracene as initiator followed by the phorbol ester 12-O-tetradecanoylphorbol-13-acetate as promoter.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenoma; Administration, Intravaginal; Animals; Carcinogens; Carcinoma; Cocarcinogenesis; Drug Synergism; Female; Hyperplasia; Leukemia, Experimental; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Models, Animal; Neoplasms, Experimental; Organ Specificity; Ovarian Neoplasms; Papilloma; Precancerous Conditions; Sarcoma, Experimental; Specific Pathogen-Free Organisms; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Vagina; Vaginal Neoplasms | 1980 |
Increased epidermal tumors and increased skin wound healing in transgenic mice overexpressing the catalytic subunit of telomerase, mTERT, in basal keratinocytes.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Catalytic Domain; Cattle; DNA-Binding Proteins; Female; Gastric Mucosa; Genes, p53; Genetic Therapy; Hyperplasia; Keratinocytes; Keratins; Mice; Mice, Knockout; Mice, Transgenic; Mouth Mucosa; Neoplasms, Experimental; Papilloma; Protein Subunits; RNA; Skin; Skin Neoplasms; Stomach; Telomerase; Telomere; Tetradecanoylphorbol Acetate; Vagina; Wound Healing | 2001 |
Keratinocyte-specific onset of serine protease BSSP expression in experimental carcinogenesis.
Topics: Animals; Biomarkers, Tumor; Carcinogens; Female; Kallikreins; Keratinocytes; Mice; Neoplasms, Experimental; Serine Endopeptidases; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2001 |
Structure-activity relationship of tubeimosides in anti-inflammatory, antitumor, and antitumor-promoting effects.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Phytogenic; Cucurbitaceae; Disease Models, Animal; Edema; Female; Male; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Molecular Structure; Neoplasms, Experimental; Saponins; Sarcoma 180; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Treatment Outcome; Triterpenes | 2001 |
Inhibition of both skin and lung tumorigenesis by Car-R mouse-derived cancer modifier loci.
Topics: Alleles; Animals; Animals, Outbred Strains; Carcinogenicity Tests; Carcinogens; Female; Genetic Predisposition to Disease; Inbreeding; Incidence; Lung Neoplasms; Male; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Papilloma; Phenotype; Polymerase Chain Reaction; Polymorphism, Genetic; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); ras Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate; Urethane | 2002 |
Targeted expression of spermidine/spermine N1-acetyltransferase increases susceptibility to chemically induced skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetyltransferases; Animals; Animals, Genetically Modified; Carcinogens; Cattle; Genetic Predisposition to Disease; Immunohistochemistry; Keratinocytes; Keratins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neoplasms, Experimental; Plasmids; Promoter Regions, Genetic; Putrescine; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 2002 |
Tumour promoter alone induces neoplastic transformation of fibroblasts from humans genetically predisposed to cancer.
Topics: Animals; Cell Adhesion; Cell Transformation, Neoplastic; Eye; Humans; Mice; Mice, Nude; Multiple Endocrine Neoplasia; Neoplasm Transplantation; Neoplasms, Experimental; Phorbols; Tetradecanoylphorbol Acetate | 1979 |
Two-stage (initiation-promotion) carcinogenesis in vivo and in vitro.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzopyrenes; Cell Transformation, Neoplastic; Cells, Cultured; Cocarcinogenesis; Croton Oil; Female; In Vitro Techniques; Mice; Models, Biological; Neoplasms, Experimental; Rats; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1978 |
Transmaternal modification of the Berenblum/Mottram experiment in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cocarcinogenesis; Female; Fetus; Maternal-Fetal Exchange; Mice; Neoplasms, Experimental; Papilloma; Pregnancy; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1978 |
Systemic two-stage carcinogenesis in the epithelium of the forestomach of mice using 7,12-dimethylbenz(a)anthracene as initiator and the phorbol ester 12-O-tetradecanoylphorbol-13-acetate as promoter.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Cocarcinogenesis; Drug Synergism; Epithelium; Female; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Phorbols; Stomach Neoplasms; Tetradecanoylphorbol Acetate | 1979 |
Potent tumor-initiating activity of the 3,4-dihydrodiol of 7,12-dimethylbenz(a)anthracene in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Female; Mice; Neoplasms, Experimental; Papilloma; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1979 |
Effects of structural changes on the tumor-promoting activity of phorbol myristate acetate on mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aldehydes; Animals; Carcinoma, Squamous Cell; Decanoates; Drug Synergism; Mice; Mice, Inbred ICR; Neoplasms, Experimental; Papilloma; Phorbols; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1979 |
Inhibition of phorbol ester-induced tumor promotion in mice by vitamin A analog and anti-inflammatory steroid.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cocarcinogenesis; Drug Synergism; Female; Fluocinolone Acetonide; Mice; Neoplasms, Experimental; Papilloma; Phorbols; Skin Neoplasms; Tetradecanoylphorbol Acetate; Vitamin A | 1979 |
Life history and histopathology of ultraviolet light-induced skin tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cocarcinogenesis; Cricetinae; Female; Mice; Neoplasms, Experimental; Neoplasms, Radiation-Induced; Papilloma; Rats; Sarcoma, Experimental; Skin Neoplasms; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 1978 |
Dynamics of neoplastic development in carcinogen-exposed tracheal mucosa.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Cell Adhesion; Cells, Cultured; Epithelium; Female; Neoplasms, Experimental; Phorbols; Rats; Rats, Inbred F344; Tetradecanoylphorbol Acetate; Time Factors; Trachea; Tracheal Neoplasms; Transplantation, Isogeneic | 1979 |
The initiation of tumours on mouse skin by dihydrodiols derived from 7,12-dimethylbenz(a)anthracene and 3-methylcholanthrene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Benz(a)Anthracenes; Chemical Phenomena; Chemistry; Female; Methylcholanthrene; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1979 |
Phorbol as a possible systemic promoting agent for skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Drug Synergism; Female; Injections, Intraperitoneal; Mice; Mice, Inbred ICR; Neoplasms, Experimental; Papilloma; Phorbols; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1976 |
On the biochemical mechanism of tumorigenesis in mouse skin. VII. The effects of tumor promoters on 3H-choline and 3H-glycerol incorporation into mouse epidermal phosphatidylcholine in relation to their effects on 3H-thymidine incorporation into DNA.
Topics: Animals; Choline; DNA, Neoplasm; Female; Glycerol; Mice; Neoplasms, Experimental; Phorbol Esters; Phorbols; Phosphatidylcholines; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1976 |
Diaplacental carcinogenesis: tumor localization and tumor incidence in NMRI mice after diaplacental initiation with DMBA and urethane and postnatal promotion and the phorbol ester TPA in a modified 2-stage Berenblum/Mottram experiment.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Abortion, Spontaneous; Administration, Oral; Administration, Topical; Animals; Benz(a)Anthracenes; Female; Genital Neoplasms, Female; Injections, Intraperitoneal; Maternal-Fetal Exchange; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Neoplasms, Multiple Primary; Organ Specificity; Phorbols; Pregnancy; Tetradecanoylphorbol Acetate; Urethane | 1977 |
Tumor persistence and regression in skin carcinogenesis. An experimental study.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Female; Mice; Neoplasm Regression, Spontaneous; Neoplasms, Experimental; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1978 |
An apparent inactivation of initiated cells by the potent inhibitor of two-stage mouse skin tumorigenesis, bis(2-chloroethyl)sulfide.
Topics: Animals; Cyclic AMP; DNA; Enzyme Induction; Esterases; Female; Isoproterenol; Mice; Mustard Compounds; Neoplasms, Experimental; Ornithine Decarboxylase; Skin; Skin Neoplasms; Sulfides; Tetradecanoylphorbol Acetate; Tosylarginine Methyl Ester | 1977 |
Increased cyclic adenosine 3':5'-monophosphate phosphodiesterase activity in the epidermis of phorbol ester-treated mouse skin and in papillomas.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Colchicine; Enzyme Induction; Female; Mice; Neoplasms, Experimental; Papilloma; Phorbol Esters; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Vinblastine | 1979 |
Studies with chlorinated dibenzo-p-dioxins, polybrominated biphenyls, and polychlorinated biphenyls in a two-stage system of mouse skin tumorigenesis: potent anticarcinogenic effects.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Carcinogens; Dioxins; Drug Interactions; Enzyme Induction; Female; Hydrocarbons, Chlorinated; Mice; Neoplasms, Experimental; Polybrominated Biphenyls; Polychlorinated Biphenyls; Polychlorinated Dibenzodioxins; Polycyclic Compounds; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1979 |
The roles of the simian virus 40 tumor antigens in transformation of Chinese hamster lung cells.
Topics: Animals; Antigens, Neoplasm; Antigens, Viral; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Lung; Mice; Mice, Nude; Mutation; Neoplasm Transplantation; Neoplasms, Experimental; Simian virus 40; Tetradecanoylphorbol Acetate; Transplantation, Heterologous | 1979 |
Effects of 12-O-tetradecanoylphorbol-13-acetate and mezerein on epidermal ornithine decarboxylase activity, isoproterenol-stimulated levels of cyclic adenosine 3':5'-monophosphate, and induction of mouse skin tumors in vivo.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Division; Cyclic AMP; Dermatitis, Contact; Diterpenes; Female; Isoproterenol; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Papilloma; Phorbol Esters; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1979 |
Comparative mutagenicity, tumor-initiating activity, carcinogenicity, and in vitro metabolism of fluorinated 5-methylchrysenes.
Topics: Animals; Carcinogens; Chrysenes; Cocarcinogenesis; Drug Evaluation, Preclinical; Female; In Vitro Techniques; Male; Mice; Microsomes, Liver; Mutagens; Neoplasms, Experimental; Phenanthrenes; Rats; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1979 |
Carcinogenicity of halogenated olefinic and aliphatic hydrocarbons in mice.
Topics: Animals; Carcinogens, Environmental; Cocarcinogenesis; Drug Evaluation, Preclinical; Female; Hydrocarbons, Halogenated; Lung Neoplasms; Male; Mice; Neoplasms, Experimental; Papilloma; Sarcoma, Experimental; Skin Neoplasms; Stomach Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1979 |
Binding of epidermal growth factor to primary and permanent cultures of mouse epidermal cells: inhibition by tumor-promoting phorbol esters.
Topics: Animals; Binding Sites; Cells, Cultured; Epidermal Growth Factor; Mice; Neoplasms, Experimental; Peptides; Phorbol Esters; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1979 |
Extracellular cytolysis by activated macrophages and granulocytes. I. Pharmacologic triggering of effector cells and the release of hydrogen peroxide.
Topics: Animals; Ascitic Fluid; BCG Vaccine; Dose-Response Relationship, Drug; Granulocytes; Hydrogen Peroxide; Kinetics; Lymphoma; Macrophages; Mice; Mycobacterium bovis; Neoplasms, Experimental; Tetradecanoylphorbol Acetate | 1979 |
Maintenance of human skin on nude mice for studies of chemical carcinogenesis.
Topics: Animals; Carcinogens; Female; Humans; Hyperplasia; Male; Mice; Mice, Nude; Models, Biological; Neoplasms, Experimental; Skin; Skin Neoplasms; Skin Transplantation; Species Specificity; Tetradecanoylphorbol Acetate; Transplantation, Heterologous; Urethane | 1979 |
Epidermal ribosome accumulation during two-stage skin tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Membranes; Mice; Neoplasms, Experimental; Precancerous Conditions; Ribosomes; RNA, Neoplasm; RNA, Ribosomal; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1977 |
Induction of the formation of new hair follicles in mouse tail epidermis by the tumor promoter 12-O-tetradecanoylphorbol-13-acetate.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Hair; Mice; Neoplasms, Experimental; Papilloma; Phorbols; Skin; Skin Neoplasms; Tail; Tetradecanoylphorbol Acetate | 1977 |
Development of a system for controlled release of benzo(a)pyrene, 7,12-dimethylbenz(a)anthracene, and phorbol ester for tumor induction in heterotopic tracheal grafts.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bees; Benz(a)Anthracenes; Benzopyrenes; Carbon; Delayed-Action Preparations; Neoplasms, Experimental; Phorbols; Rats; Rats, Inbred F344; Solubility; Tetradecanoylphorbol Acetate; Trachea; Tracheal Neoplasms; Transplantation, Isogeneic; Waxes | 1978 |
Tumorigenicity of the dihydrodiols of dibenzo(a,h)anthracene on mouse skin and in newborn mice.
Topics: Animals; Animals, Newborn; Benz(a)Anthracenes; Carcinogens; Female; Liver Neoplasms; Lung Neoplasms; Male; Mice; Neoplasms, Experimental; Pregnancy; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1979 |
Epidermal prostaglandins after topical application of a tumor promotor.
Topics: Administration, Topical; Animals; Male; Mice; Neoplasms, Experimental; Phorbols; Prostaglandins E; Prostaglandins F; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1979 |
Comparison of the skin tumor initiating activity of 3-methylcholanthrene and 3,11-dimethylcholanthrene in mice.
Topics: Animals; Female; Methylcholanthrene; Mice; Neoplasms, Experimental; Papilloma; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1979 |
Effect of phorbol ester tumor promoters on the expression of melanogenesis in B-16 melanoma cells.
Topics: Animals; Cell Differentiation; Clone Cells; Melanins; Melanocyte-Stimulating Hormones; Melanoma; Mice; Neoplasms, Experimental; Phorbol Esters; Phorbols; Tetradecanoylphorbol Acetate | 1979 |
Tumorigenic activity of 3-methylcholanthrene metabolites on mouse skin and in newborn mice.
Topics: Administration, Topical; Animals; Animals, Newborn; Carcinogens; Cocarcinogenesis; Drug Administration Schedule; Female; Injections, Intraperitoneal; Liver Neoplasms; Lung Neoplasms; Male; Methylcholanthrene; Mice; Neoplasms, Experimental; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1979 |
Suppression of natural antitumour defence mechanisms by phorbol esters.
Topics: Animals; Cytotoxicity, Immunologic; Depression, Chemical; Immunity, Innate; Killer Cells, Natural; Macrophages; Mice; Neoplasms, Experimental; Phorbols; Rats; Spleen; Tetradecanoylphorbol Acetate | 1979 |
Correlation of anchorage-independent growth with tumorigenicity of chemically transformed mouse epidermal cells.
Topics: Agar; Animals; Cell Adhesion; Cell Division; Cell Transformation, Neoplastic; Clone Cells; Methylnitronitrosoguanidine; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Neoplasms, Experimental; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transplantation, Isogeneic | 1978 |
Skin tumor-initiating activities of the twelve isomeric phenols of benzo(a)pyrene.
Topics: Animals; Benzopyrenes; Female; Isomerism; Mice; Neoplasms, Experimental; Papilloma; Skin; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Time Factors | 1978 |
Inhibition of 12-O-tetradecanoylphorbol-13-acetate-induced ornithine decarboxylase activity in mouse epidermis by vitamin A analogs (retinoids).
Topics: Animals; Carboxy-Lyases; Drug Evaluation, Preclinical; Female; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Phorbols; Polyamines; Skin; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Vitamin A | 1978 |
Effect of aging in two-stage carcinogenesis on mouse skin with phorbol myristate acetate as promoting agent.
Topics: Aging; Animals; Female; Mice; Mice, Inbred ICR; Neoplasms, Experimental; Phorbols; Skin Neoplasms; Statistics as Topic; Tetradecanoylphorbol Acetate | 1978 |
Tumor-promoting activity of 2,3-dihydrophorbol myristate acetate and phorbolol myristate acetate in mouse skin.
Topics: Animals; Dermatitis, Contact; Female; Mice; Mice, Inbred ICR; Neoplasms, Experimental; Papilloma; Phorbols; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1978 |
Tumor-initiating activity of fluorinated 5-methylchrysenes.
Topics: Animals; Biotransformation; Chrysenes; Female; Mice; Neoplasms, Experimental; Phenanthrenes; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1978 |
Evidence that benzo(a)anthracene 3,4-diol-1,2-epoxide is an ultimate carcinogen on mouse skin.
Topics: Animals; Benz(a)Anthracenes; Biotransformation; Carcinogens; Female; Mice; Neoplasms, Experimental; Papilloma; Skin Neoplasms; Stereoisomerism; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1978 |
Metabolic conversion of 12-O-tetradecanoylphorbol-13-acetate in adult and newborn mouse skin and mouse liver microsomes.
Topics: Animals; Animals, Newborn; Esterases; Female; In Vitro Techniques; Metabolic Clearance Rate; Mice; Mice, Inbred BALB C; Microsomes, Liver; Neoplasms, Experimental; Phorbol Esters; Phorbols; Skin; Tetradecanoylphorbol Acetate | 1978 |
Non-phorbol mouse skin tumor promoters do not mimic phorbol myristate acetate in its effects on chick embryo fibroblasts.
Topics: Acetates; Animals; Anthralin; Cantharidin; Carcinogens; Cell Membrane; Chick Embryo; Cytochalasin B; Deoxyglucose; Fibroblasts; Glycoproteins; Lauric Acids; Neoplasms, Experimental; Oleic Acids; Palmitic Acids; Phenols; Phorbols; Skin Neoplasms; Stearic Acids; Tetradecanoylphorbol Acetate | 1978 |
Comparative tumor initiating activity of 10-methylbenzo-[a]pyrene, 7,10-dimethylbenzo[a]pyrene and benzo[a]pyrene.
Topics: Animals; Benzopyrenes; Biotransformation; Female; Keratoacanthoma; Mice; Neoplasms, Experimental; Papilloma; Skin; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1978 |
Photosensitized reactions and carcinogenesis.
Topics: Animals; Carcinoma, Squamous Cell; Cocarcinogenesis; DNA; Female; Methoxsalen; Mice; Mice, Nude; Neoplasms, Experimental; Neoplasms, Radiation-Induced; Photochemotherapy; Skin Neoplasms; Species Specificity; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 1978 |
The induction of ornithine decarboxylase activity and its control in mouse skin epidermis.
Topics: Adenosylmethionine Decarboxylase; Alkaloids; Amines; Animals; Carboxy-Lyases; Enzyme Induction; Epidermis; Female; Indomethacin; Mice; Neoplasms, Experimental; Nucleotides, Cyclic; Ornithine Decarboxylase; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin; Ultraviolet Rays | 1978 |
Two-stage malignant transformation in hamster embryo cells.
Topics: Agar; Animals; Benz(a)Anthracenes; Cell Transformation, Neoplastic; Cricetinae; Methylcholanthrene; Neoplasm Transplantation; Neoplasms, Experimental; Phorbols; Tetradecanoylphorbol Acetate; Time Factors | 1979 |
Marked differences in the skin tumor-initiating activities of the optical enantiomers of the diastereomeric benzo(a)pyrene 7,8-diol-9,10-epoxides.
Topics: Animals; Benzopyrenes; Carcinogens; Epoxy Compounds; Female; Mice; Neoplasms, Experimental; Papilloma; Skin; Skin Neoplasms; Stereoisomerism; Tetradecanoylphorbol Acetate | 1979 |
Correlation of the inhibition by retinoids of tumor promoter-induced mouse epidermal ornithine decarboxylase activity and of skin tumor promotion.
Topics: Animals; Carboxy-Lyases; Enzyme Induction; Female; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Papilloma; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Tretinoin; Vitamin A | 1979 |
Inhibition of two-stage carcinogenesis in mouse skin with bis(2-chloroethyl)sulfide.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Carcinoma, Squamous Cell; Female; Mice; Mice, Inbred ICR; Mustard Compounds; Neoplasms, Experimental; Papilloma; Phorbols; Skin Neoplasms; Sulfides; Tetradecanoylphorbol Acetate | 1976 |
Regression kinetics of mouse skin papillomas.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antilymphocyte Serum; Dose-Response Relationship, Drug; Female; Half-Life; Mice; Neoplasm Regression, Spontaneous; Neoplasms, Experimental; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1976 |
Transmaternal variation of the Berenblum experiment with NMRI-mice: tumour initiation with DMBA via mothers milk followed by promotion with the phorbol ester TPA.
Topics: Animals; Animals, Newborn; Benz(a)Anthracenes; Carcinoma, Squamous Cell; Female; Mice; Milk; Neoplasms, Experimental; Papilloma; Tetradecanoylphorbol Acetate | 1976 |
Measurement and significance of subclinical effects of chemicals.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Allergens; Animals; Carbon Monoxide Poisoning; Carboxyhemoglobin; Drug Synergism; Environmental Exposure; Environmental Pollutants; Humans; Mice; Neoplasms, Experimental; Paralysis; Tetradecanoylphorbol Acetate; Tritolyl Phosphates | 1976 |
Epidermal cell proliferation and promoting ability of phorbol esters.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Division; Dose-Response Relationship, Drug; Drug Synergism; Edema; Female; Hyperplasia; Inflammation; Mice; Neoplasms, Experimental; Papilloma; Phorbol Esters; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1976 |
Diaplacental carcinogenesis: initiation with the carcinogens dimethylbenzanthracene (DMBA) and urethane during fetal life and postnatal promotion with the phorbol ester TPA in a modified 2-stage Berenblum/Mottram experiment.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Drug Synergism; Female; Fetus; Gestational Age; Maternal-Fetal Exchange; Mice; Neoplasms, Experimental; Phorbols; Pregnancy; Skin Neoplasms; Tetradecanoylphorbol Acetate; Urethane | 1976 |
Improved tumour yields by means of a TPA-DMBA-TPA variation of the Berenrlum-Mottram experiment on the back skin of NMRI mice. The effect of stationary hyperplasia without inflammation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Carcinoma; Female; Hyperplasia; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Papilloma; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1976 |
Effect of phorbol myristate acetate on the recovery of spontaneous and ultraviolet light-induced 6-thioguanine and ouabain-resistant Chinese hamster cells.
Topics: Animals; Cell Survival; Cells, Cultured; Cricetinae; DNA Repair; Drug Resistance; Mutation; Neoplasms, Experimental; Ouabain; Phorbols; Tetradecanoylphorbol Acetate; Thioguanine; Time Factors; Ultraviolet Rays | 1977 |
Histone phosphorylation and synthesis of DNA and RNA during phases of proliferation and differentiation induced in mouse epidermis by the tumor promoter 12-O-tetradecanoyl-phorbol-13-acetate.
Topics: Animals; Cell Differentiation; Cell Division; DNA; DNA, Neoplasm; Female; Histones; Mice; Neoplasms, Experimental; Phorbols; Phosphorus; RNA; RNA, Neoplasm; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1977 |
Effects of antiinflammatory agents on mouse skin tumor promotion, epidermal DNA synthesis, phorbol ester-induced cellular proliferation, and production of plasminogen activator.
Topics: Animals; Anti-Inflammatory Agents; Cell Division; Cells, Cultured; Depression, Chemical; DNA; Female; Fluocinolone Acetonide; Fluocinonide; Mice; Neoplasms, Experimental; Phorbol Esters; Phorbols; Plasminogen Activators; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1977 |
Effect of colchicine injection prior to the initiating phase of two-stage skin carcinogenesis in mice.
Topics: Animals; Cell Division; Colchicine; Female; Mice; Mice, Inbred ICR; Mitosis; Neoplasms, Experimental; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Urethane | 1977 |
Vitamin A acid (retinoic acid), a potent inhibitor of 12-O-tetradecanoyl-phorbol-13-acetate-induced ornithine decarboxylase activity in mouse epidermis.
Topics: Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Drug Administration Schedule; Enzyme Induction; Female; In Vitro Techniques; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Papilloma; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin; Vitamin A | 1977 |
Marked differences in the tumor-initiating activity of optically pure (+)- and (-)-trans-7,8-dihydroxy-7,8-dihydrobenzo(a)pyrene on mouse skin.
Topics: Animals; Benzopyrenes; Female; Mice; Microsomes, Liver; Neoplasms, Experimental; Papilloma; Skin Neoplasms; Stereoisomerism; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1977 |
Skin-tumor-initiating ability of benzo(a)pyrene-7,8-diol-9,10-epoxide (anti) when applied topically in tetrahydrofuran.
Topics: Acetone; Animals; Benzene; Benzopyrenes; Carcinogens; Drug Interactions; Female; Furans; Mice; Neoplasms, Experimental; Papilloma; Skin Neoplasms; Solvents; Stereoisomerism; Tetradecanoylphorbol Acetate | 1977 |
Comparison of the tumor-initiating activities of benzo(a)pyrene arene oxides and diol-epoxides.
Topics: Animals; Benzopyrenes; Epoxy Compounds; Female; Glycols; Mice; Neoplasms, Experimental; Oxides; Papilloma; Skin Neoplasms; Stereoisomerism; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1977 |
Tumour-initiating activities on mouse skin of dihydrodiols derived from benzo[a]pyrene.
Topics: Animals; Benzopyrenes; Carcinoma, Squamous Cell; Female; Fibrosarcoma; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1976 |
Selective promoting activity of phorbol myristate acetate in experimental skin carcinogenesis.
Topics: Animals; Carcinoma, Squamous Cell; Female; Fibrosarcoma; Male; Methylcholanthrene; Mice; Neoplasms, Experimental; Phorbols; Precancerous Conditions; Rhabdomyosarcoma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1976 |
Decrease of epidermal histidase activity by tumor-promoting phorbol esters.
Topics: Ammonia-Lyases; Animals; Benz(a)Anthracenes; Carcinogens; Depression, Chemical; Histidine Ammonia-Lyase; Male; Mice; Mice, Nude; Neoplasms, Experimental; Phorbols; Polysorbates; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Urethane | 1975 |
Acetic acid, a potent stimulator of mouse epidermal macromolecular synthesis and hyperplasia but with weak tumor-promoting ability.
Topics: Acetates; Animals; Croton Oil; Cytidine; DNA; Dose-Response Relationship, Drug; Female; Hyperplasia; Leucine; Mice; Neoplasms, Experimental; Papilloma; Proteins; RNA; Skin; Skin Neoplasms; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Thymidine | 1975 |
Glucocorticoid, androgen, and retinoic acid regulation of glutathione S-transferase gene expression in hamster smooth muscle tumor cells.
Topics: Animals; Bucladesine; Cell Line; Cricetinae; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glutathione Transferase; Isoenzymes; Muscle, Smooth; Neoplasms, Experimental; Phenobarbital; RNA, Messenger; Testosterone; Tetradecanoylphorbol Acetate; Tretinoin; Triamcinolone Acetonide | 1992 |
Transformation of non-tumorigenic osteoblast-like human osteosarcoma cells by hexavalent chromates: alteration of morphology, induction of anchorage-independence and proteolytic function.
Topics: Animals; Carcinogens; Cell Adhesion; Cell Division; Cell Survival; Cell Transformation, Neoplastic; Chromates; Electrochemistry; Humans; Hydrolysis; Male; Methylcholanthrene; Mice; Mice, Nude; Neoplasms, Experimental; Osteoblasts; Osteosarcoma; Plasminogen Activators; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Urokinase-Type Plasminogen Activator | 1992 |
Tumoricidal properties of rat peritoneal macrophages activated with various activators depend on nitrogen oxid synthesis.
Topics: Animals; Arginine; Cells, Cultured; Chromium Radioisotopes; Culture Media; Female; Immunotherapy; Interferon-gamma; Interleukin-2; Lipopolysaccharides; Macrophage Activation; Macrophages; Neoplasms, Experimental; Nitrites; Peritoneal Cavity; Rats; Rats, Inbred Lew; Recombinant Proteins; Tetradecanoylphorbol Acetate; Zymosan | 1992 |
Transplacental and transgeneration carcinogenic effect of 7,12-dimethylbenz[a]anthracene: relationship with ras oncogene activation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Fetus; Gene Expression Regulation; Genes, ras; Lung Neoplasms; Male; Mice; Mutation; Neoplasms, Experimental; Pregnancy; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1992 |
Antitumor activity of UCN-01, a selective inhibitor of protein kinase C, in murine and human tumor models.
Topics: Alkaloids; Animals; Antineoplastic Agents; Cell Division; Down-Regulation; ErbB Receptors; Humans; Male; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Neoplasms, Experimental; Oncogenes; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
[Genetics of cancerogenesis. Experimental model in mice].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Drug Resistance; Incidence; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Phenotype; Tetradecanoylphorbol Acetate | 1991 |
Transformation of mouse skin endothelial cells in vivo by direct application of plasmid DNA encoding the human T24 H-ras oncogene.
Topics: Animals; Base Sequence; Blotting, Southern; Cell Transformation, Neoplastic; Cloning, Molecular; Electrophoresis, Polyacrylamide Gel; Genes, ras; Humans; Mice; Mice, Inbred Strains; Molecular Sequence Data; Neoplasms, Experimental; Plasmids; Polymerase Chain Reaction; Precipitin Tests; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1991 |
Absence of the c-Ha-ras codon 61 point mutation in murine solid tumors induced by subcutaneously applied 7,12-dimethylbenzanthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alleles; Animals; Base Sequence; Codon; Female; Fibrosarcoma; Gene Expression Regulation, Neoplastic; Genes, ras; Heterozygote; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Mutation; Neoplasms, Experimental; Oncogenes; Polymorphism, Restriction Fragment Length; Tetradecanoylphorbol Acetate | 1990 |
Phorbol ester-induced tumor promotion by downregulation of protein kinase C.
Topics: Animals; Cocarcinogenesis; Down-Regulation; Isoenzymes; Mice; Neoplasms, Experimental; Protein Kinase C; Tetradecanoylphorbol Acetate | 1991 |
Effect of macrophages on interleukin-2 (IL-2)- and IL-4-induced murine lymphokine-activated killer activity.
Topics: Animals; Cell Communication; Cell Line; Cytotoxicity, Immunologic; Humans; Interleukin-2; Interleukin-4; Killer Cells, Lymphokine-Activated; Kinetics; Lymphocyte Activation; Macrophages; Male; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Recombinant Proteins; Spleen; Tetradecanoylphorbol Acetate | 1991 |
Two classes of continuous cell lines established from Syrian hamster 9 day gestation embryos: preneoplastic cells and progenitor cells.
Topics: Animals; Cell Differentiation; Cell Division; Cell Line; Cell Survival; Cricetinae; Embryo, Mammalian; Epidermal Growth Factor; Gestational Age; Mesocricetus; Neoplasms, Experimental; Phorbol Esters; Ploidies; Stem Cells; Tetradecanoylphorbol Acetate | 1990 |
Oxidation of polycyclic hydrocarbons by oxygen radicals.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Benzo(a)pyrene; Cytochrome P-450 Enzyme System; DNA; DNA Damage; Female; Free Radicals; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Oxidation-Reduction; Polycyclic Compounds; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1990 |
Fluorine probes for investigating the mechanism of activation of indeno[1,2,3-cd]pyrene to a tumorigenic agent.
Topics: Animals; Carcinogenicity Tests; DNA, Neoplasm; Female; Fluorine; Mice; Neoplasms, Experimental; Pyrenes; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1990 |
Mechanism of calcium ionophore A23187-induced priming of bone marrow-derived macrophages for tumor cell killing: relationship to priming by interferon.
Topics: Animals; Bone Marrow Cells; Calcimycin; Cytotoxicity, Immunologic; Diglycerides; Dose-Response Relationship, Drug; Interferons; Lipopolysaccharides; Macrophages; Male; Mice; Neoplasms, Experimental; Phorbols; Platelet Activating Factor; Tetradecanoylphorbol Acetate | 1985 |
Evidence for the molecular dissociation of binding and post-binding functions in cytotoxic T lymphocytes.
Topics: Animals; Cell Adhesion; Clone Cells; Cycloheximide; Cytotoxicity, Immunologic; Epitopes; Mice; Neoplasms, Experimental; Protein Biosynthesis; T-Lymphocytes, Cytotoxic; Tetradecanoylphorbol Acetate; Time Factors | 1985 |
Role of protein kinase C in regulation of gene expression and relevance to tumor promotion.
Topics: Amino Acid Sequence; Animals; Cells, Cultured; DNA; Enzyme Activation; Gene Expression Regulation; Mice; Molecular Sequence Data; Neoplasms, Experimental; Protein Biosynthesis; Protein Kinase C; Proteins; Risk; RNA; Tetradecanoylphorbol Acetate | 1987 |
Modulation by adriamycin, daunomycin, verapamil, and trifluoperazine of the biochemical processes linked to mouse skin tumor promotion by 12-O-tetradecanoylphorbol-13-acetate.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Daunorubicin; DNA; Doxorubicin; Female; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; RNA; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Trifluoperazine; Verapamil | 1989 |
Antitumor-promoting activity of eperisone.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Calcium Channel Blockers; Female; HeLa Cells; Mice; Mice, Inbred ICR; Neoplasms, Experimental; Phosphates; Phospholipids; Propiophenones; Tetradecanoylphorbol Acetate | 1989 |
Inhibition of initiator-promoter-induced skin tumorigenesis in female SENCAR mice fed a vitamin A-deficient diet and reappearance of tumors in mice fed a diet adequate in retinoid or beta-carotene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; beta Carotene; Carotenoids; Cocarcinogenesis; Diet; Female; Liver; Male; Mice; Neoplasms, Experimental; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin; Vitamin A Deficiency; Weight Loss | 1989 |
Increased tumour incidence and skin tumour promotion in two generations of descendants of 7,12-dimethylbenz[a]anthracene-treated pregnant mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Male; Mice; Neoplasms, Experimental; Pedigree; Pregnancy; Prenatal Exposure Delayed Effects; Risk Factors; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1989 |
Diacylglycerols enhance the anti-tumor effect of glucocorticoid on L5178Y lymphoblasts in vivo.
Topics: Adrenalectomy; Adrenocorticotropic Hormone; Animals; Antineoplastic Combined Chemotherapy Protocols; Corticosterone; Diglycerides; Enzyme Activation; Glycerides; Lymphocytes; Male; Mice; Mice, Inbred DBA; Neoplasm Transplantation; Neoplasms, Experimental; Protein Kinase C; Tetradecanoylphorbol Acetate; Triamcinolone Acetonide; Tumor Cells, Cultured | 1989 |
12-O-tetradecanoyl-phorbol-13-acetate-induced differentiation of human neuroblastoma cells is not accompanied by an increase in the intracellular concentration of cyclic AMP.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Carrier Proteins; Clone Cells; Colchicine; Cyclic AMP; Mice; Neoplasms, Experimental; Neuroblastoma; Phorbols; Protein Binding; Tetradecanoylphorbol Acetate | 1985 |
Disturbances in growth control and gene expression in a C3H/10T1/2 cell line that stably overproduces protein kinase C.
Topics: Animals; Blotting, Northern; Cell Division; Cell Line; Gene Expression Regulation; In Vitro Techniques; Mice; Mice, Nude; Neoplasms, Experimental; Protein Kinase C; RNA, Messenger; Tetradecanoylphorbol Acetate; Transfection | 1989 |
Differential expression of an 80-kDa protein kinase C substrate in preneoplastic and neoplastic mouse JB6 cells.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Mice; Mice, Inbred BALB C; Neoplasm Proteins; Neoplasms, Experimental; Phosphorylation; Precancerous Conditions; Protein Kinase C; Substrate Specificity; Tetradecanoylphorbol Acetate | 1989 |
Characterization of the transformation properties of Shope fibroma virus.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cocarcinogenesis; DNA, Viral; Fibroblasts; Fibroma Virus, Rabbit; Mice; Neoplasms, Experimental; Poxviridae; Rabbits; Tetradecanoylphorbol Acetate; Transfection; Ultraviolet Rays | 1988 |
"Hit and run" transformation of mouse C127 cells by bovine papillomavirus type 4: the viral DNA is required for the initiation but not for maintenance of the transformed phenotype.
Topics: Animals; Bovine papillomavirus 1; Bovine papillomavirus 4; Cell Division; Cell Line; Cell Transformation, Viral; DNA, Circular; DNA, Viral; Fibroblasts; Mice; Mice, Nude; Neoplasms, Experimental; Papillomaviridae; Tetradecanoylphorbol Acetate; Virus Replication | 1988 |
Neutrophil-mediated nonoxidative tumor lysis stimulated by high concentrations of phorbol myristate acetate.
Topics: Anaerobiosis; Animals; Catalase; Cattle; Cell Membrane Permeability; Cell Survival; Dose-Response Relationship, Drug; Exocytosis; Granulomatous Disease, Chronic; Hydrogen Peroxide; Immunotherapy; In Vitro Techniques; Neoplasms, Experimental; Neutrophils; Peroxidase; Superoxide Dismutase; Tetradecanoylphorbol Acetate | 1988 |
[The actions of TPA-type as well as non-TPA type tumor promoters and their mechanism(s) in tumor promotion].
Topics: Acrylamides; Animals; Arachidonic Acid; Arachidonic Acids; Carcinogens; Cnidarian Venoms; Enzyme Activation; Humans; Lyngbya Toxins; Mice; Neoplasms, Experimental; Phorbols; Plant Extracts; Protein Kinase C; Receptors, Cell Surface; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Thapsigargin | 1986 |
Induction of vimentin synthesis in a murine myeloma cell line by TPA is strongly dependent on the composition of the cell culture medium.
Topics: Animals; Cell Division; Cell Line; Culture Media; Fluorescent Antibody Technique; Intermediate Filament Proteins; Mice; Neoplasms, Experimental; Plasmacytoma; Poly A; Protein Biosynthesis; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vimentin | 1988 |
Effects of various inhibitors of arachidonic acid oxygenation on macrophage superoxide release and tumoricidal activity.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Auranofin; Aurothioglucose; Cells, Cultured; Cyclooxygenase Inhibitors; Cytotoxicity, Immunologic; Lipoxygenase Inhibitors; Lymphokines; Macrophage Activation; Macrophage-Activating Factors; Macrophages; Male; Mice; Neoplasms, Experimental; Phagocytosis; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1985 |
Reversion of bovine papillomavirus-induced transformation and immortalization by a xanthate compound.
Topics: Animals; Bovine papillomavirus 1; Bridged-Ring Compounds; Cell Transformation, Viral; Clone Cells; Cricetinae; DNA, Viral; Fibroblasts; Mesocricetus; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Norbornanes; Papillomaviridae; RNA, Neoplasm; RNA, Viral; Tetradecanoylphorbol Acetate; Thiocarbamates; Thiones; Transcription, Genetic | 1985 |
Spontaneous tumor cytolysis mediated by inflammatory neutrophils: dependence upon divalent cations and reduced oxygen intermediates.
Topics: Animals; Calcium; Cytotoxicity, Immunologic; Edetic Acid; Egtazic Acid; Female; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Inflammation; Magnesium; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Neutrophils; Nitroblue Tetrazolium; Oxygen; Peroxidase; Superoxides; Tetradecanoylphorbol Acetate | 1986 |
Characterization of Fischer rat embryo (CREF) cells transformed by bovine papillomavirus type 1.
Topics: Adenoviruses, Human; Animals; Bovine papillomavirus 1; Cell Cycle; Cell Line; Cell Transformation, Viral; Epidermal Growth Factor; ErbB Receptors; Gene Expression Regulation; Mice; Neoplasms, Experimental; Papillomaviridae; Rats; Receptors, Cell Surface; Tetradecanoylphorbol Acetate; Virus Replication | 1986 |
Influence of dispase and angiogenesis factors on the growth of human xenografts.
Topics: Alprostadil; Angiogenesis Inducing Agents; Animals; Colonic Neoplasms; Endopeptidases; Growth Substances; Humans; Male; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Tetradecanoylphorbol Acetate; Transplantation, Heterologous | 1988 |
Berberine sulfate inhibits tumor-promoting activity of teleocidin in two-stage carcinogenesis on mouse skin.
Topics: 3-O-Methylglucose; 9,10-Dimethyl-1,2-benzanthracene; Animals; Berberine; Berberine Alkaloids; Biological Transport; Carcinogens; Cells, Cultured; Female; Fibroblasts; HeLa Cells; In Vitro Techniques; Lyngbya Toxins; Methylglucosides; Mice; Mice, Inbred ICR; Neoplasms, Experimental; Phosphates; Phospholipids; Radioisotopes; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1986 |
Inhibition of the prenatal dimethylbenz[a]anthracene-induced tumour initiation in mice by prior administration of 7,8-benzoflavone.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoma; Administration, Oral; Animals; Benzoflavones; Cocarcinogenesis; Female; Flavonoids; Lung Neoplasms; Mice; Neoplasms, Experimental; Papilloma; Pregnancy; Prenatal Exposure Delayed Effects; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1986 |
Role of protein kinase C and intracellular calcium mobilization in the induction of macrophage tumoricidal activity by interferon-gamma.
Topics: Aminoquinolines; Calcimycin; Calcium; Cytotoxicity, Immunologic; Imidazoles; Interferon-gamma; Macrophage Activation; Macrophages; Neoplasms, Experimental; Protein Kinase C; Tetradecanoylphorbol Acetate; Trifluoperazine | 1986 |
Analysis of deficiencies in IFN-gamma-mediated priming for tumor cytotoxicity in peritoneal macrophages from A/J mice.
Topics: Animals; Ascitic Fluid; Calcium; Cells, Cultured; Cytotoxicity, Immunologic; Immunity, Cellular; Interferon-gamma; Macrophage Activation; Macrophages; Mice; Mice, Inbred A; Mice, Inbred C57BL; Neoplasms, Experimental; Protein Kinase C; Tetradecanoylphorbol Acetate | 1986 |
Differential carcinogenic effects of intraperitoneal initiation with 7,12-dimethylbenz(a)anthracene or urethane and topical promotion with 12-O-tetradecanoylphorbol-13-acetate in skin and internal tissues of female SENCAR and BALB/c mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Cocarcinogenesis; Female; Injections, Intraperitoneal; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Neoplasms, Experimental; Skin Neoplasms; Species Specificity; Tetradecanoylphorbol Acetate; Urethane | 1986 |
Restoration of lipopolysaccharide-mediated cytotoxic macrophage induction in C3H/HeJ mice by interferon-gamma or a calcium ionophore.
Topics: Animals; Calcimycin; Calcium; Cytotoxicity, Immunologic; Dose-Response Relationship, Drug; Interferon-gamma; Lipopolysaccharides; Macrophage Activation; Macrophages; Mice; Mice, Inbred C3H; Mice, Inbred ICR; Neoplasms, Experimental; Recombinant Proteins; Tetradecanoylphorbol Acetate | 1987 |
Stimulation of histamine synthesis from tumour cells by concanavalin A and A23187.
Topics: Animals; Calcimycin; Cell Line; Concanavalin A; Histamine; Mice; Neoplasms, Experimental; Tetradecanoylphorbol Acetate | 1987 |
Synthetic analogues (indolactams) of (-)-indolactam-V are new congeners of the teleocidin class of tumor promoters.
Topics: Animals; Cell Adhesion; Cell Line; Dose-Response Relationship, Drug; Enzyme Induction; Humans; Indoles; Lactams; Leukemia, Myeloid, Acute; Lyngbya Toxins; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Protein Kinase C; Skin; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1987 |
Persistence of carcinogenic effect in intact progeny of mice treated transplacentally with 7,12-dimethylbenz[a]anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Fetus; Lung Neoplasms; Male; Mammary Neoplasms, Experimental; Mice; Neoplasms, Experimental; Pregnancy; Sex Factors; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1987 |
Inflammation, oxidative DNA damage, and carcinogenesis.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; DNA Damage; Hydrogen Peroxide; Inflammation; Macrophage Activation; Macrophages; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Oxidation-Reduction; Tetradecanoylphorbol Acetate | 1987 |
Effect of two inducers of cellular differentiation on the glutathione status of human HL-60 promyelocytic leukaemia and A549 lung carcinoma cells.
Topics: Animals; Carcinoma; Cell Differentiation; Cell Line; Dimethyl Sulfoxide; Formamides; Glutathione; Humans; Leukemia, Myeloid, Acute; Lung Neoplasms; Mice; Neoplasms, Experimental; Tetradecanoylphorbol Acetate | 1987 |
Enhancement of selective tumor cell binding by activated murine macrophages in response to phorbol myristate acetate.
Topics: Animals; Cell Adhesion; Cell Line; Cytoskeleton; Hydrogen Peroxide; Kinetics; Macrophage Activation; Macrophages; Mice; Mycobacterium bovis; Neoplasms, Experimental; Phorbols; Temperature; Tetradecanoylphorbol Acetate; Time Factors; Trypsin | 1986 |
The mRNA coding for the secreted protease transin is expressed more abundantly in malignant than in benign tumors.
Topics: Animals; Carcinoma, Squamous Cell; Cell Transformation, Viral; Endopeptidases; Gene Expression Regulation; Matrix Metalloproteinase 3; Mice; Neoplasm Proteins; Neoplasms, Experimental; Papilloma; RNA, Messenger; RNA, Neoplasm; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1986 |
Tumor progression in vitro: the paradoxical natural antibody and complement-selected phenotype.
Topics: Animals; Antibodies, Neoplasm; Antibody-Dependent Cell Cytotoxicity; Complement Activation; Cytotoxicity, Immunologic; Immunity, Cellular; Immunity, Innate; Immunoglobulin Isotypes; Immunologic Surveillance; In Vitro Techniques; Killer Cells, Natural; Mice; Mice, Inbred DBA; Neoplasms, Experimental; Tetradecanoylphorbol Acetate | 1987 |
In vivo induction of tumor variants by phorbol 12-myristate 13-acetate.
Topics: Animals; Antigens, Surface; Female; Immunization; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Phenotype; Tetradecanoylphorbol Acetate | 1987 |
[Enhancement of the transforming activity of simian adenovirus S5 and of the DNA from human adenovirus type I by benzo(a)pyrene and TPA].
Topics: Adenoviridae; Adenoviruses, Human; Adenoviruses, Simian; Animals; Animals, Newborn; Benzo(a)pyrene; Cell Line; Cell Transformation, Viral; Cells, Cultured; Chlorocebus aethiops; Cricetinae; DNA, Viral; Humans; Kidney; Mesocricetus; Neoplasms, Experimental; Phorbols; Rats; Tetradecanoylphorbol Acetate; Time Factors | 1986 |
Ionizing radiation as an initiator in the mouse two-stage model of skin tumor formation.
Topics: Animals; Carcinogens; Carcinoma, Squamous Cell; Cocarcinogenesis; Female; Mice; Neoplasms, Experimental; Papilloma; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; X-Rays | 1986 |
Anti-mutagenesis and anti-promotion by apigenin, robinetin and indole-3-carbinol.
Topics: 2-Acetylaminofluorene; Animals; Benzo(a)pyrene; Chamomile; Female; Flavonoids; Indoles; Methylnitronitrosoguanidine; Methylnitrosourea; Mice; Mice, Inbred Strains; Mutagens; Mutation; Neoplasms, Experimental; Oils, Volatile; Ornithine Decarboxylase; Plant Extracts; Plants, Medicinal; Skin; Tetradecanoylphorbol Acetate | 1986 |
Induction of tumor cell resistance to macrophage-mediated lysis by phorbol esters: a postbinding event.
Topics: Animals; Caenorhabditis elegans Proteins; Carrier Proteins; Cell Line; Cytotoxicity, Immunologic; Lymphoma; Macrophage Activation; Macrophages; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Phorbol Esters; Protein Kinase C; Rats; Rats, Inbred WF; Receptors, Drug; Receptors, Immunologic; Tetradecanoylphorbol Acetate; Thymoma; Thymus Neoplasms | 1986 |
Effect of capsaicin on croton oil and TPA induced tumorigenesis and inflammation.
Topics: Animals; Capsaicin; Croton Oil; Female; Inflammation; Mice; Neoplasms, Experimental; Tetradecanoylphorbol Acetate | 1986 |
Pathology of aging female SENCAR mice used as controls in skin two-stage carcinogenesis studies.
Topics: Acetone; Aging; Animals; Cardiovascular System; Female; Genitalia, Female; Hematopoietic System; Kidney; Liver; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Respiratory System; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1986 |
Correlation of murine susceptibility to tumor, parasite and bacterial challenge with altered cell-mediated immunity following systemic exposure to the tumor promoter phorbol myristate acetate.
Topics: Animals; Cell Line; Cytotoxicity, Immunologic; Female; Immunity, Cellular; Immunity, Innate; Killer Cells, Natural; Listeriosis; Macrophage Activation; Melanoma; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Phorbols; T-Lymphocytes, Cytotoxic; Tetradecanoylphorbol Acetate; Trichinellosis | 1985 |
[Role of cell-cell interaction in tumor promotion].
Topics: Animals; Carcinogens; Cell Communication; Cell Transformation, Neoplastic; Cricetinae; Extracellular Space; Homeostasis; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Phorbol Esters; Protein Kinase C; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1986 |
[TPA enhancement of the mutagenic and transforming action of bovine adenovirus type 3 on cultured mouse cells].
Topics: Adenoviridae; Animals; Cattle; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Mice; Mice, Inbred C3H; Mutation; Neoplasm Transplantation; Neoplasms, Experimental; Phorbols; Tetradecanoylphorbol Acetate | 1985 |
A strain of hairless mouse susceptible to tumorigenesis by TPA alone: studies with 8-methoxypsoralen and solar simulated radiation.
Topics: Animals; Cocarcinogenesis; Female; Methoxsalen; Mice; Mice, Hairless; Neoplasms, Experimental; Phorbols; PUVA Therapy; Sunlight; Tetradecanoylphorbol Acetate | 1985 |