Compounds > tetradecanoylphorbol acetate
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tetradecanoylphorbol acetate and Experimental Hepatoma

tetradecanoylphorbol acetate has been researched along with Experimental Hepatoma in 99 studies

Research

Studies (99)

TimeframeStudies, this research(%)All Research%
pre-199038 (38.38)18.7374
1990's54 (54.55)18.2507
2000's7 (7.07)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chang, CH; Chang, TJ; Chang, YJ; Ho, TY; Hsiang, CY; Lee, TW; Lin, WJ; Yu, CY1
Azuine, MA; Ichiishi, E; Kapadia, GJ; Konoshima, T; Mukainake, T; Nishino, H; Okuda, Y; Sridhar, R; Takasaki, M; Tokuda, H; Tsuruta, A1
Diwan, BA; Waalkes, MP; Ward, JM1
Bulla, GA; Kraus, DM1
Evdotienko, IuV; Kovaleva, EV; Potselueva, MM; Pustovidko, AV; Shatalin, IuV1
Bhide, SV; Munir, KM; Rao, KV1
Endo, Y; Imai, Y; Kaneko, Y; Matsuzaki, F; Oda, T1
Byus, CV; Donato, NJ; Wu, VS1
Ganelina, LSh; Ignatova, TN; Pashinin, IuV1
Byus, CV; Kulkarni, RK; Trevillyan, JM1
Kahn, CR; Lauris, V; Takayama, S; White, MF1
Byus, CV; Wu, VS3
Fujiki, H; Hayashi, K; Kakizoe, T; Makino, R; Sugimura, T1
Lützelschwab, R; Wälder, L1
Becker, FF1
O'Brien, TG; Saladik, D1
Bréhier, A; Croquet, F; Davy, J; Ducher, L; Féger, J; Gil, S1
Kim, G; Yurkow, EJ2
Dickson, AJ; Yang, SH1
Bischer, P; Cantu, AR; Pavone, A; Reiners, JJ; Schöller, A1
Lampe, PD1
Perletti, GP; Piccinini, F; Porro, D; Smeraldi, C1
Kawasaki, H; Nakamura, T; Schmidt, EV; Shiota, G1
Hosomi, Y; Ogawa, W; Roth, RA1
Reik, A; Schütz, G; Stewart, AF1
Jiang, W; Johnson, MD; Kahn, SM; Tomita, N; Weinstein, IB; Zhou, P1
Granner, D; Hall, R; Imai, E; Mitchell, J; Noisin, E; O'Brien, R1
Bosch, F; Fillat, C; Valera, A1
Finkenzeller, G; Häussinger, D; Lang, F; Newsome, W1
Byus, CV; Hawel, L; Tjandrawinata, RR1
Konoshima, T; Kozuka, M; Takasaki, M; Tokuda, H1
Babcock, KL; Hertzberg, EL; Neveu, MJ; Nicholson, BJ; Paul, DL; Pitot, HC1
Arizono, K; Brady, FO; Peterson, KL1
Fuchimoto, S; Iwagaki, H; Kimura, T; Nonaka, Y; Orita, K1
Barlow, JW; Kolliniatis, E; Scholz, GH; Stockigt, JR; Topliss, DJ1
Anderson, L; Butler, AP; Kang, DC; Kumar, AP; Mar, PK; Martinez, LA; Montgomery, RL; Zhao, B1
Chatterjee, N; Gupta, NK; Osterman, JC; Zou, C1
Fujiki, H; Kim, SJ; Komori, A; Kozu, T; Lim, IK; Ohta, T; Okabe, S; Sueoka, E; Sueoka, N; Suganuma, M1
Chen, DS; Cheng, AL; Chuang, SE; Fine, RL; Lay, JD; Liao, CM; Yeh, KH1
Bortoff, KD; Hrywna, Y; Messina, JL; Zhu, CC1
Bernuau, D; Durand-Schneider, AM; Lardeux, B; Nadori, F; Rahmani, M1
Murata, T; Nakajima, M; Yamaguchi, M1
Duc, NM; Ichiishi, E; Kasai, R; Konoshima, T; Murakami, T; Nishino, H; Takasaki, M; Tokuda, H; Yamasaki, K1
Misawa, H; Yamaguchi, M1
Chang, RL; Conney, AH; Jerina, DM; Kumar, S; Lehr, RE; Shirai, N; Wood, AW1
Chun, YJ; Kim, MY; Lee, BY; Ryu, CK; Yang, SA1
Heinrich, PC; Koj, A; Kordula, T; Rose-John, S1
Ban, J; Weber, G1
Jentel, JJ; Lacson, RG; Oehler, DT; Unterman, TG1
Avruch, J; Bierer, BE; Calvo, V; Grove, JR; Price, DJ1
Messina, JL1
Arizono, K; Brady, FO; Garrett, SH; Xiong, X1
Chan, SO; Wong, SS; Yeung, DC2
Adams, AK; Hanausek, M; Mirowski, M; Sherman, U; Slaga, TJ; Walaszek, Z1
Messina, JL; Weinstock, RS3
Farese, RV; Ishizuka, T; Messina, JL; Standaert, ML; Weinstock, RS1
Bezrukov, VM; Krasil'nikov, MA; Shatskaia, VA1
Farooqui, SM; Morgan, WT; Smith, A1
Moreno-Sánchez, R; Torres-Márquez, ME1
Hosokawa, M; Maki, T; Sato, K; Satoh, T1
Butler, AP; Mar, PK; McDonald, FF; Ramsay, RL1
Butler, AP; Cohn, WB; Mar, PK; Montgomery, RL1
Mori, T; Murata, A; Ogawa, M; Oka, Y; Uda, K; Yasuda, T1
Harder, G; Jamieson, JC; Woloski, BM1
Kato, K; Morimura, S; Tashiro, F; Ueno, Y1
McCann, JA; Messina, JL1
Hatanaka, T; Hongyo, T; Kinuta, M; Nakajima, H; Nomura, T1
Roesch, SF; Wiebel, FJ1
Dull, TJ; Kahn, CR; Stegmann, EW; Ullrich, A; White, MF1
Baumann, H; Isseroff, H; Jahreis, GP; Latimer, JJ1
Alcántara, R; García-Sáinz, JA; Hernández-Sotomayor, SM; Mas-Oliva, J1
Denda, A; Eimoto, H; Kinugasa, T; Kitazawa, S; Konishi, Y; Takashima, Y; Tsujiuchi, T; Tsutsumi, M; Ura, H1
Goodman, S; Koontz, JW1
Aujard, C; Lafarge-Frayssinet, C; Morel-Chany, E1
Mesnil, M; Montesano, R; Yamasaki, H1
Chu, DT; Granner, DK1
Chu, D; Granner, DK; Sasaki, K1
Esau, B; Goodman, SA; Koontz, JW1
Capeau, J; Caron, M; Cherqui, G; Lascols, O; Picard, J; Wicek, D1
Larner, A; Larner, J; Sato, T; Ye, T1
Kahn, CR; Takayama, S; White, MF1
Byus, CV; Perisic, O; Traugh, JA; Trevillyan, JM1
Bertrand, J; Capeau, J; Caron, M; Cherqui, G; Picard, J; Wicek, D1
Dieter, R; Koontz, J; Roy, A; Taub, R1
Hamlin, J; Larner, J; Messina, JL1
Blackshear, PJ; Halsey, DL; Hovis, JG; Huang, JK; Nemenoff, RA; Stumpo, DJ1
Adey, WR; Byus, CV; Kartun, K; Pieper, S1
Cresteil, T; Lambiotte, M; Thierry, N1
Bykorez, AI; Grabovaia, AR; Kononenko, LI1
Butler, AP; Byus, CV; Slaga, TJ1
Blake, AD; Strader, CD1
Butler, AP; McDonald, FF1
Boynton, AL; Kleine, LP; Whitfield, JF1

Reviews

1 review(s) available for tetradecanoylphorbol acetate and Experimental Hepatoma

ArticleYear
Multihormonal regulation of phosphoenolpyruvate carboxykinase gene transcription. The dominant role of insulin.
    Annals of the New York Academy of Sciences, 1986, Volume: 478

    Topics: Animals; Bucladesine; Cell Line; Cyclic AMP; Glucocorticoids; Insulin; Kinetics; Liver Neoplasms, Experimental; Phosphoenolpyruvate Carboxykinase (GTP); Protein Biosynthesis; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate; Thionucleotides; Transcription, Genetic

1986

Other Studies

98 other study(ies) available for tetradecanoylphorbol acetate and Experimental Hepatoma

ArticleYear
Noninvasive bioluminescent and microPET imaging for the regulation of NF-kappaB in human hepatoma-bearing mice.
    Anticancer research, 2009, Volume: 29, Issue:4

    Topics: Animals; Antimetabolites, Antineoplastic; Carcinogens; Diagnostic Imaging; Female; Fluorodeoxyglucose F18; Humans; Liver Neoplasms, Experimental; Luciferases; Luminescent Measurements; Methotrexate; Mice; Mice, Nude; Mice, SCID; NF-kappa B; Positron-Emission Tomography; Radiopharmaceuticals; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

2009
Chemoprevention of DMBA-induced UV-B promoted, NOR-1-induced TPA promoted skin carcinogenesis, and DEN-induced phenobarbital promoted liver tumors in mice by extract of beetroot.
    Pharmacological research, 2003, Volume: 47, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Beta vulgaris; Betacyanins; Body Weight; Carcinogens; Diethylnitrosamine; Dose-Response Relationship, Drug; Female; Hydroxylamines; Indoles; Liver Neoplasms, Experimental; Mice; Mice, Inbred ICR; Neoplasms, Radiation-Induced; Phenobarbital; Plant Extracts; Plant Roots; Skin Neoplasms; Tetradecanoylphorbol Acetate; Ultraviolet Rays

2003
Induction of tumors of the liver, lung, ovary and adrenal in adult mice after brief maternal gestational exposure to inorganic arsenic: promotional effects of postnatal phorbol ester exposure on hepatic and pulmonary, but not dermal cancers.
    Carcinogenesis, 2004, Volume: 25, Issue:1

    Topics: Adrenal Gland Neoplasms; Animals; Arsenic; Female; Fetus; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Mice; Mice, Inbred C3H; Organ Specificity; Ovarian Neoplasms; Skin Neoplasms; Tetradecanoylphorbol Acetate

2004
Defective NF-kappaB signaling in dedifferentiated hepatoma cells.
    Somatic cell and molecular genetics, 1999, Volume: 25, Issue:5-6

    Topics: Animals; Base Sequence; Cell Differentiation; DNA Primers; Electrophoretic Mobility Shift Assay; Lipopolysaccharides; Liver Neoplasms, Experimental; Liver Regeneration; NF-kappa B; Rats; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

1999
[Cytotoxic action of polymorphonuclear leukocytes on tumor and normal cells during ascite tumor development in vitro and in vivo].
    Tsitologiia, 2005, Volume: 47, Issue:1

    Topics: Animals; Carcinoma, Ehrlich Tumor; Coculture Techniques; Cytotoxicity, Immunologic; Erythrocytes; Hemoglobins; Liver Neoplasms, Experimental; Luminescent Measurements; Male; Neutrophils; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate

2005
Effect of hexachlorocyclohexane on diethylnitrosamine-induced hepatocarcinogenesis in rat and its failure to promote skin tumors on dimethylbenz[a]anthracene initiation in mouse.
    Carcinogenesis, 1984, Volume: 5, Issue:4

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Diethylnitrosamine; Drug Interactions; Female; gamma-Glutamyltransferase; Hexachlorocyclohexane; Liver; Liver Neoplasms, Experimental; Nitrosamines; Phorbols; Rats; Rats, Inbred Strains; Skin Neoplasms; Tetradecanoylphorbol Acetate

1984
Teleocidin B inhibits binding of epidermal growth factor to cellular receptors probably by the same mechanism as phorbol esters.
    Biochemical and biophysical research communications, 1980, Dec-16, Volume: 97, Issue:3

    Topics: Alkaloids; Animals; Cell Division; Cells, Cultured; Epidermal Growth Factor; ErbB Receptors; Indoles; Kinetics; Liver Neoplasms, Experimental; Lyngbya Toxins; Peptides; Rats; Receptors, Cell Surface; Tetradecanoylphorbol Acetate

1980
Growth state-dependent alterations in the ability of 12-O-tetradecanoylphorbol-13-acetate to increase ornithine decarboxylase activity in Reuber h35 Hepatoma cells.
    Cancer research, 1981, Volume: 41, Issue:9 Pt 1

    Topics: Animals; Bucladesine; Carboxy-Lyases; Cell Line; Dexamethasone; DNA; Enzyme Induction; Liver Neoplasms, Experimental; Ornithine Decarboxylase; Phorbols; Polyamines; Tetradecanoylphorbol Acetate; Time Factors

1981
[Effect of the tumor promotor 12-o-tetradecanoyl phorbol-13--acetate on cyclic adenosine monophosphate levels in cell cultures. Relation to cell proliferation].
    Tsitologiia, 1983, Volume: 25, Issue:11

    Topics: Animals; Cell Division; Cell Membrane Permeability; Cells, Cultured; Cyclic AMP; Drug Resistance; L Cells; Liver Neoplasms, Experimental; Mice; Mutation; Phorbols; Tetradecanoylphorbol Acetate; Time Factors

1983
Tumor-promoting phorbol esters stimulate the phosphorylation of ribosomal protein S6 in quiescent Reuber H35 hepatoma cells.
    The Journal of biological chemistry, 1984, Jan-25, Volume: 259, Issue:2

    Topics: Animals; Cyclic AMP; Dose-Response Relationship, Drug; Liver Neoplasms, Experimental; Phorbol Esters; Phorbols; Phosphorylation; Rats; Ribosomal Protein S6; Ribosomal Proteins; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Time Factors

1984
Phorbol esters modulate insulin receptor phosphorylation and insulin action in cultured hepatoma cells.
    Proceedings of the National Academy of Sciences of the United States of America, 1984, Volume: 81, Issue:24

    Topics: Animals; Insulin; Kinetics; Liver Neoplasms, Experimental; Macromolecular Substances; Molecular Weight; Phorbols; Phosphorylation; Rats; Receptor, Insulin; Tetradecanoylphorbol Acetate

1984
A role for ornithine in the regulation of putrescine accumulation and ornithine decarboxylase activity in Reuber H35 hepatoma cells.
    Biochimica et biophysica acta, 1984, May-22, Volume: 804, Issue:1

    Topics: Animals; Arginase; Arginine; Cell Adhesion; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Induction; Liver Neoplasms, Experimental; Ornithine; Ornithine Decarboxylase; Putrescine; Tetradecanoylphorbol Acetate

1984
Increase in frequency of appearance of cadmium-resistant cells induced by various tumor promoters; evidence for the induction of gene amplification.
    Princess Takamatsu symposia, 1983, Volume: 14

    Topics: Animals; Cadmium; Carcinogens; Cells, Cultured; Cricetinae; Cricetulus; Drug Resistance; Gene Amplification; Humans; Liver Neoplasms, Experimental; Metallothionein; Oncogenes; Tetradecanoylphorbol Acetate; Urinary Bladder Neoplasms

1983
Effects of 12-O-tetradecanoylphorbol-13-acetate (TPA), retinoic acid and diazepam on intercellular communication in a monolayer of rat liver epithelial cells.
    Experimental cell research, 1984, Volume: 152, Issue:1

    Topics: Animals; Cell Communication; Cell Line; Diazepam; Epithelium; Hypoxanthines; Intercellular Junctions; Liver; Liver Neoplasms, Experimental; Phorbols; Rats; Tetradecanoylphorbol Acetate; Tretinoin

1984
Presidential address. Recent concepts of initiation and promotion in carcinogenesis.
    The American journal of pathology, 1981, Volume: 105, Issue:1

    Topics: 2-Acetylaminofluorene; Animals; Carcinogens; Diethylnitrosamine; DNA; Humans; Intestinal Polyps; Liver Neoplasms, Experimental; Mice; Rats; Skin Neoplasms; Tetradecanoylphorbol Acetate

1981
The induction of ornithine decarboxylase by tumor promoting phorbol ester analogues in Reuber H35 hepatoma cells.
    Life sciences, 1981, Nov-02, Volume: 29, Issue:18

    Topics: Animals; Carboxy-Lyases; Cell Line; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Enzyme Induction; Liver Neoplasms, Experimental; Ornithine Decarboxylase; Phorbol Esters; Phorbols; Polyamines; Rats; Tetradecanoylphorbol Acetate

1981
Differences in the metabolism of 12-O-[3H]tetradecanoylphorbol-13-acetate and [3H]phorbol-12,13-didecanoate by cells in culture.
    Cancer research, 1980, Volume: 40, Issue:12

    Topics: Adipose Tissue; Animals; Cells, Cultured; Chick Embryo; Cricetinae; Epidermis; Humans; Liver Neoplasms, Experimental; Mice; Phorbol Esters; Phorbols; Species Specificity; Structure-Activity Relationship; Tetradecanoylphorbol Acetate

1980
Differential expression of five protein kinase C isoenzymes in FAO and HepG2 hepatoma cell lines compared with normal rat hepatocytes.
    Biochemical and biophysical research communications, 1995, Dec-14, Volume: 217, Issue:2

    Topics: Amino Acid Sequence; Animals; Carcinoma, Hepatocellular; Cell Compartmentation; Cell Division; Cell Membrane; Cytosol; Enzyme Activation; Humans; Isoenzymes; Liver; Liver Neoplasms, Experimental; Mice; Molecular Sequence Data; Molecular Weight; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1995
Effects of chromium on basal and insulin-induced tyrosine phosphorylation in H4 hepatoma cells: comparison with phorbol-12-myristate-13-acetate and sodium orthovanadate.
    Molecular pharmacology, 1995, Volume: 47, Issue:4

    Topics: Animals; Chromium; Insulin; Insulin Receptor Substrate Proteins; Liver Neoplasms, Experimental; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Phosphotyrosine; Protein Kinase C; Proteins; Rats; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine; Vanadates

1995
Inhibitors of signalling identify differential control processes responsible for selective effects of insulin on the expression of phosphoenolpyruvate carboxykinase and gene 33 in rat H4 hepatoma cells.
    The Biochemical journal, 1995, Sep-01, Volume: 310 ( Pt 2)

    Topics: Androstadienes; Animals; Antibiotics, Antineoplastic; Carrier Proteins; Cell Line; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Insulin; Insulin Antagonists; Intracellular Signaling Peptides and Proteins; Kinetics; Liver Neoplasms, Experimental; Phosphoenolpyruvate Carboxykinase (GTP); Polyenes; Protein Biosynthesis; Rats; RNA, Messenger; Signal Transduction; Sirolimus; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Wortmannin

1995
Suppression of cytochrome P450 Cyp1a-1 induction in murine hepatoma 1c1c7 cells by 12-O-tetradecanoylphorbol-13-acetate and inhibitors of protein kinase C.
    Archives of biochemistry and biophysics, 1993, Volume: 301, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Induction; Isoquinolines; Liver Neoplasms, Experimental; Naphthalenes; Piperazines; Polycyclic Compounds; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1993
Analyzing phorbol ester effects on gap junctional communication: a dramatic inhibition of assembly.
    The Journal of cell biology, 1994, Volume: 127, Issue:6 Pt 2

    Topics: Animals; Cell Communication; Coloring Agents; Connexin 43; Freeze Fracturing; Gap Junctions; Liver Neoplasms, Experimental; Microscopy, Electron; Morphogenesis; Phosphorylation; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1994
Involvement of the alpha isoenzyme of protein kinase C in the growth inhibition induced by phorbol esters in MH1C1 hepatoma cells.
    Biochemical and biophysical research communications, 1994, Dec-30, Volume: 205, Issue:3

    Topics: Alkaloids; Animals; Arachidonic Acid; Cell Division; Gene Expression Regulation, Enzymologic; Isoenzymes; Liver Neoplasms, Experimental; Oligonucleotides, Antisense; Protein Kinase C; Protein Kinase C-alpha; Rats; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1994
Inhibitory effect of hepatocyte growth factor against FaO hepatocellular carcinoma cells may be associated with changes of intracellular signalling pathways mediated by protein kinase C.
    Research communications in molecular pathology and pharmacology, 1994, Volume: 85, Issue:3

    Topics: Animals; Blotting, Northern; Carcinoma, Hepatocellular; Cell Division; Cells, Cultured; DNA; DNA, Neoplasm; Drug Combinations; Hepatocyte Growth Factor; Liver; Liver Neoplasms, Experimental; Protein Kinase C; Proto-Oncogene Proteins c-myc; Rats; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1994
Activation of protein kinase C stimulates the tyrosine phosphorylation and guanosine triphosphatase-activating protein association of p60 in rat hepatoma cells.
    Endocrinology, 1995, Volume: 136, Issue:2

    Topics: Animals; Down-Regulation; GTPase-Activating Proteins; Insulin; Liver Neoplasms, Experimental; Phosphorylation; Protein Kinase C; Proteins; Rats; Receptor, Insulin; Second Messenger Systems; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine

1995
Cross-talk modulation of signal transduction pathways: two mechanisms are involved in the control of tyrosine aminotransferase gene expression by phorbol esters.
    Molecular endocrinology (Baltimore, Md.), 1994, Volume: 8, Issue:4

    Topics: Animals; Base Sequence; Cell Line; Chromatin; Colforsin; Corticosterone; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; DNA; Enhancer Elements, Genetic; Enzyme Induction; Genes; Liver; Liver Neoplasms, Experimental; Molecular Sequence Data; Protein Binding; Protein Kinase C; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats; Receptors, Steroid; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured; Tyrosine Transaminase

1994
Molecular cloning of TPAR1, a gene whose expression is repressed by the tumor promoter 12-O-tetradecanoylphorbol 13-acetate (TPA).
    Experimental cell research, 1994, Volume: 215, Issue:2

    Topics: Amino Acid Sequence; Animals; Base Sequence; Cell Line; Cell Line, Transformed; Cloning, Molecular; DNA, Complementary; Down-Regulation; Gene Expression; Humans; Interleukin-8; Liver Neoplasms, Experimental; Liver Regeneration; Mice; Molecular Sequence Data; Rats; Restriction Mapping; RNA, Messenger; Sequence Homology, Amino Acid; Tetradecanoylphorbol Acetate

1994
Integration of multiple signals through a complex hormone response unit in the phosphoenolpyruvate carboxykinase gene promoter.
    Molecular endocrinology (Baltimore, Md.), 1994, Volume: 8, Issue:5

    Topics: Animals; Base Composition; Base Sequence; Binding Sites; Chloramphenicol O-Acetyltransferase; Consensus Sequence; Insulin; Liver Neoplasms, Experimental; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Phosphoenolpyruvate Carboxykinase (GTP); Promoter Regions, Genetic; Rats; Sequence Deletion; Tetradecanoylphorbol Acetate; Transfection; Tretinoin; Tumor Cells, Cultured

1994
Epidermal growth factor inhibits phosphoenolpyruvate carboxykinase gene expression in rat hepatocytes in primary culture.
    FEBS letters, 1993, Mar-08, Volume: 318, Issue:3

    Topics: Animals; Bucladesine; Cells, Cultured; Enzyme Activation; Epidermal Growth Factor; Gene Expression; Liver; Liver Neoplasms, Experimental; Male; Phosphoenolpyruvate Carboxykinase (GTP); Protein Kinase C; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine Transaminase

1993
Increase of c-jun mRNA upon hypo-osmotic cell swelling of rat hepatoma cells.
    FEBS letters, 1994, Mar-07, Volume: 340, Issue:3

    Topics: Animals; Cell Size; Enzyme Activation; Indoles; Liver Neoplasms, Experimental; Maleimides; Osmolar Concentration; Protein Kinase C; Proto-Oncogene Proteins c-jun; Rats; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1994
Selective putrescine export is regulated by insulin and ornithine in Reuber H35 hepatoma cells.
    Biochimica et biophysica acta, 1994, May-26, Volume: 1222, Issue:1

    Topics: Animals; Biological Transport; Culture Media; Insulin; Liver Neoplasms, Experimental; Ornithine; Putrescine; Rats; Spermidine; Spermine; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured; Verapamil

1994
[Anti-tumor promoting activities of kampo prescriptions. II. Inhibitory effects of souseiryu-to on two-stage carcinogenesis of mouse skin tumors and mouse pulmonary tumors].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1994, Volume: 114, Issue:4

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Viral; Cell Cycle; Drug Screening Assays, Antitumor; Drugs, Chinese Herbal; Female; Liver Neoplasms, Experimental; Lung Neoplasms; Mice; Mice, Inbred ICR; Skin Neoplasms; Tetradecanoylphorbol Acetate

1994
Colocalized alterations in connexin32 and cytochrome P450IIB1/2 by phenobarbital and related liver tumor promoters.
    Cancer research, 1994, Jun-15, Volume: 54, Issue:12

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Barbiturates; Carcinogens; Cell Communication; Connexins; Cytochrome P-450 Enzyme System; Enzyme Induction; Gap Junction beta-1 Protein; Gap Junctions; Immunoblotting; Liver; Liver Neoplasms, Experimental; Male; Phenobarbital; Protein Processing, Post-Translational; Rats; Rats, Inbred F344; RNA, Messenger; Steroid Hydroxylases; Tetradecanoylphorbol Acetate

1994
Inhibitors of Ca2+ channels, calmodulin and protein kinases prevent A23187 and other inductions of metallothionein mRNA in EC3 rat hepatoma cells.
    Life sciences, 1993, Volume: 53, Issue:12

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 2-Chloroadenosine; Animals; Calcimycin; Calcium; Calcium Channel Blockers; Calmodulin; Gallic Acid; Isoquinolines; Liver Neoplasms, Experimental; Metallothionein; Norepinephrine; Piperazines; Protein Kinase Inhibitors; Rats; RNA, Messenger; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Verapamil

1993
Effect of reactive oxygen intermediates on the in vitro invasive capacity of tumor cells and liver metastasis in mice.
    International journal of cancer, 1993, Jul-30, Volume: 54, Issue:6

    Topics: Animals; Catalase; Electron Spin Resonance Spectroscopy; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred Strains; Neoplasm Invasiveness; Reactive Oxygen Species; Recombinant Proteins; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1993
Influence of calmodulin antagonists and calcium channel blockers on triiodothyronine uptake by rat hepatoma and myoblast cell lines.
    Metabolism: clinical and experimental, 1993, Volume: 42, Issue:3

    Topics: Analysis of Variance; Animals; Cadmium; Calcium; Calcium Channel Blockers; Calmodulin; Cell Line; Diltiazem; Imidazoles; Iodine Radioisotopes; Liver Neoplasms, Experimental; Magnesium; Muscles; Nifedipine; Protein Kinase C; Rats; Sulfonamides; Tetradecanoylphorbol Acetate; Trifluoperazine; Triiodothyronine; Tumor Cells, Cultured; Verapamil

1993
Characterization of novel phorbol ester- and serum-responsive sequences of the rat ornithine decarboxylase gene promoter.
    Molecular carcinogenesis, 1995, Volume: 14, Issue:4

    Topics: Animals; Base Sequence; Binding Sites; Cyclic AMP Response Element-Binding Protein; DNA; Down-Regulation; Enzyme Induction; Fibroblasts; Gene Deletion; Gene Expression Regulation, Enzymologic; Growth Substances; Liver Neoplasms, Experimental; Molecular Sequence Data; Mutagenesis, Site-Directed; Nuclear Proteins; Ornithine Decarboxylase; Promoter Regions, Genetic; Protein Kinase C; Rats; Sensitivity and Specificity; Tetradecanoylphorbol Acetate

1995
Chromium induces a persistent activation of mitogen-activated protein kinases by a redox-sensitive mechanism in H4 rat hepatoma cells.
    Cancer research, 1996, May-01, Volume: 56, Issue:9

    Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Chromium; Enzyme Activation; Liver Neoplasms, Experimental; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Oxidation-Reduction; Peroxides; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1996
Cloning and characterization of the promoter region of a gene encoding a 67-kDa glycoprotein.
    The Journal of biological chemistry, 1997, May-09, Volume: 272, Issue:19

    Topics: Aminopeptidases; Animals; Base Sequence; Carcinogens; Cloning, Molecular; Glycoproteins; Liver Neoplasms, Experimental; Molecular Sequence Data; Promoter Regions, Genetic; Rats; Sequence Deletion; Tetradecanoylphorbol Acetate; Transfection

1997
Expression of the tumor necrosis factor alpha gene and early response genes by nodularin, a liver tumor promoter, in primary cultured rat hepatocytes.
    Journal of cancer research and clinical oncology, 1997, Volume: 123, Issue:8

    Topics: Animals; Carcinogens; Cells, Cultured; Enzyme Inhibitors; Gene Expression; Genes, fos; Genes, Immediate-Early; Genes, jun; Liver; Liver Neoplasms, Experimental; Male; Marine Toxins; Microcystins; Peptides, Cyclic; Rats; Rats, Inbred F344; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

1997
Inhibition of the membrane translocation and activation of protein kinase C, and potentiation of doxorubicin-induced apoptosis of hepatocellular carcinoma cells by tamoxifen.
    Biochemical pharmacology, 1998, Feb-15, Volume: 55, Issue:4

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Hormonal; Apoptosis; Biological Transport, Active; Doxorubicin; Drug Resistance; Drug Synergism; Enzyme Activation; Fluorescent Dyes; Humans; Isoenzymes; Liver Neoplasms, Experimental; Protein Kinase C; ras Proteins; Rhodamine 123; Rhodamines; Tamoxifen; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1998
Insulin induction of pip 92, CL-6, and novel mRNAs in rat hepatoma cells.
    Endocrine, 1997, Volume: 7, Issue:2

    Topics: 3T3 Cells; Animals; Anisomycin; Gene Expression Regulation; Genes, Immediate-Early; Immediate-Early Proteins; Insulin; Intracellular Signaling Peptides and Proteins; Liver Neoplasms, Experimental; Membrane Proteins; Mice; Mice, Inbred BALB C; Nucleic Acid Synthesis Inhibitors; Protein Kinase C; Proteins; Rats; RNA, Messenger; Swine; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured

1997
Hepatocyte growth factor activates the AP-1 complex: a comparison between normal and transformed rat hepatocytes.
    Journal of hepatology, 1999, Volume: 30, Issue:5

    Topics: Animals; Cell Line, Transformed; Cell Nucleus; Cells, Cultured; Chloramphenicol O-Acetyltransferase; Dimerization; Gene Expression Regulation; Genes, fos; Genes, jun; Genes, Reporter; Hepatocyte Growth Factor; Liver Neoplasms, Experimental; Luciferases; Male; Nuclear Proteins; Phenotype; Proto-Oncogene Proteins c-jun; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription, Genetic; Transcriptional Activation; Transfection; Tumor Cells, Cultured

1999
Expression of calcium-binding protein regucalcin mRNA in the cloned rat hepatoma cells (H4-II-E) is stimulated through Ca2+ signaling factors: involvement of protein kinase C.
    Molecular and cellular biochemistry, 1999, Volume: 198, Issue:1-2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Agonists; Calcium Signaling; Calcium-Binding Proteins; Carboxylic Ester Hydrolases; Cattle; Gene Expression Regulation, Enzymologic; Intracellular Signaling Peptides and Proteins; Liver Neoplasms, Experimental; Male; Protein Kinase C; Rats; Rats, Wistar; RNA, Messenger; Sulfotransferases; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1999
Cancer chemopreventive activity of majonoside-R2 from Vietnamese ginseng, Panax vietnamensis.
    Cancer letters, 1999, Dec-01, Volume: 147, Issue:1-2

    Topics: Alkylating Agents; Animals; Anticarcinogenic Agents; Carcinogenicity Tests; Carcinogens; Diethylnitrosamine; Female; Focal Nodular Hyperplasia; Ginsenosides; Liver Neoplasms, Experimental; Mice; Mice, Inbred ICR; Mice, Inbred SENCAR; Nitrates; Nitro Compounds; Panax; Papilloma; Phenobarbital; Plants, Medicinal; Saponins; Skin Neoplasms; Tetradecanoylphorbol Acetate; Vietnam

1999
Involvement of hepatic nuclear factor I binding motif in transcriptional regulation of Ca(2+)-binding protein regucalcin gene.
    Biochemical and biophysical research communications, 2000, Mar-05, Volume: 269, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Amino Acid Motifs; Animals; Base Sequence; Binding Sites; Bucladesine; Calcium-Binding Proteins; Carboxylic Ester Hydrolases; CCAAT-Enhancer-Binding Proteins; DNA; DNA Primers; DNA-Binding Proteins; Gene Expression Regulation; In Vitro Techniques; Insulin; Intracellular Signaling Peptides and Proteins; Liver; Liver Neoplasms, Experimental; Male; Molecular Sequence Data; Mutation; NFI Transcription Factors; Promoter Regions, Genetic; Protein Binding; Rats; Rats, Wistar; Sulfotransferases; Tetradecanoylphorbol Acetate; Transcription Factors; Tumor Cells, Cultured; Y-Box-Binding Protein 1

2000
Tumorigenicity of four optically active bay-region 3,4-diol 1, 2-epoxides and other derivatives of the nitrogen heterocycle dibenz[c,h]acridine on mouse skin and in newborn mice.
    Carcinogenesis, 2000, Volume: 21, Issue:11

    Topics: Acridines; Animals; Animals, Newborn; Bay-Region, Polycyclic Aromatic Hydrocarbon; Carcinogens; Epoxy Compounds; Female; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Mice; Pregnancy; Skin; Skin Neoplasms; Stereoisomerism; Structure-Activity Relationship; Tetradecanoylphorbol Acetate

2000
Induction of cytochrome P450 1A1 gene expression by a vitamin K3 analog in mouse hepatoma Hepa-1c1c7 cells.
    Molecules and cells, 2001, Oct-31, Volume: 12, Issue:2

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Aryl Hydrocarbon Receptor Nuclear Translocator; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Cytochrome P-450 Enzyme System; DNA-Binding Proteins; Gene Expression; HL-60 Cells; Humans; Liver Neoplasms, Experimental; Mice; Quinolines; Receptors, Aryl Hydrocarbon; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Transcription Factors; Tumor Cells, Cultured; Vitamin K 3

2001
Interferon-gamma regulates alpha 2-macroglobulin and alpha 1-antichymotrypsin expression on the pretranslational level in HepG2 cells.
    Folia histochemica et cytobiologica, 1992, Volume: 30, Issue:4

    Topics: alpha 1-Antichymotrypsin; alpha-Macroglobulins; Animals; DNA Probes; Humans; Interferon-gamma; Liver Neoplasms, Experimental; Protein Biosynthesis; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1992
Synergistic action of tiazofurin and difluorodeoxycytidine on differentiation and cytotoxicity.
    Biochemical and biophysical research communications, 1992, Apr-30, Volume: 184, Issue:2

    Topics: Animals; Antimetabolites, Antineoplastic; Cell Differentiation; Cell Line; Cell Survival; Deoxycytidine; Dose-Response Relationship, Drug; Drug Synergism; Female; Gemcitabine; Humans; IMP Dehydrogenase; Kinetics; Leukemia, Promyelocytic, Acute; Liver Neoplasms, Experimental; Models, Biological; Ovarian Neoplasms; Pancreatic Neoplasms; Rats; Ribavirin; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Stem Cell Assay

1992
Divergent effects of phorbol esters and insulin on insulin-like growth factor binding protein-1 (IGFBP-1) production and mRNA in rat H4IIE hepatoma cells.
    Biochemical and biophysical research communications, 1992, Jan-15, Volume: 182, Issue:1

    Topics: Animals; Blotting, Northern; Carrier Proteins; DNA Probes; Insulin; Insulin-Like Growth Factor Binding Proteins; Insulin-Like Growth Factor I; Kinetics; Liver Neoplasms, Experimental; Phorbol 12,13-Dibutyrate; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1992
Rapamycin-induced inhibition of the 70-kilodalton S6 protein kinase.
    Science (New York, N.Y.), 1992, Aug-14, Volume: 257, Issue:5072

    Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Chromatography, Ion Exchange; Cyclosporine; Immunosuppressive Agents; Insulin; Kinetics; Liver Neoplasms, Experimental; Polyenes; Protein Kinase Inhibitors; Protein Kinases; Recombinant Proteins; Ribosomal Protein S6 Kinases; Ribosomes; Sirolimus; Tacrolimus; Tetradecanoylphorbol Acetate; Transfection

1992
Rapid regulation of albumin transcription by insulin and phorbol esters in rat hepatoma cells.
    Biochimica et biophysica acta, 1992, Oct-27, Volume: 1137, Issue:2

    Topics: Albumins; Alkaloids; Animals; Cycloheximide; Gene Expression Regulation; Insulin; Kinetics; Liver Neoplasms, Experimental; Naphthalenes; Phosphoenolpyruvate Carboxykinase (GTP); Polycyclic Compounds; Protein Kinase C; Rats; Staurosporine; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured

1992
Phorbol ester induction of rat hepatic metallothionein in vivo and in vitro.
    The International journal of biochemistry, 1992, Volume: 24, Issue:10

    Topics: Animals; Blotting, Northern; Cells, Cultured; Enzyme Induction; Liver; Liver Neoplasms, Experimental; Male; Metallothionein; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1992
Transcription induction of c-Ki-ras with the tumour promoter 12-O-tetradecanoylphorbol-13-acetate (TPA) in normal and transformed liver cells.
    Molecular and cellular biochemistry, 1992, Nov-04, Volume: 117, Issue:1

    Topics: Animals; Carcinogens; Cell Line, Transformed; Cell Nucleus; Genes, ras; Half-Life; Liver Neoplasms, Experimental; Protein Biosynthesis; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Reference Values; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic

1992
An enzyme-linked immunosorbent assay for p65 oncofetal protein and its potential as a new marker for cancer risk assessment in rodents and humans.
    Progress in clinical and biological research, 1992, Volume: 374

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biomarkers, Tumor; Choline; Choline Deficiency; Diethylnitrosamine; Enzyme-Linked Immunosorbent Assay; Female; Humans; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred Strains; Neoplasms; Oncogene Proteins; Rats; Rats, Inbred Strains; Risk Factors; Skin Neoplasms; Tetradecanoylphorbol Acetate

1992
Regulation of beta-actin gene transcription by insulin and phorbol esters.
    Experimental cell research, 1992, Volume: 200, Issue:2

    Topics: Actins; Animals; Dose-Response Relationship, Drug; Gene Expression Regulation; In Vitro Techniques; Insulin; Liver Neoplasms; Liver Neoplasms, Experimental; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Time Factors; Transcription, Genetic; Tubulin; Tumor Cells, Cultured

1992
Role of protein kinase C in insulin's regulation of c-fos transcription.
    The Journal of biological chemistry, 1992, May-05, Volume: 267, Issue:13

    Topics: Animals; Blotting, Western; Cell Membrane; Enzyme Activation; Gene Expression Regulation; Genes, fos; Insulin; Isoenzymes; Liver Neoplasms, Experimental; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tubulin; Tumor Cells, Cultured

1992
[Regulation of the phospholipid turnover rate and protein kinase C activity as a necessary stage in the realization of the growth-inhibiting effect of dexamethasone on hepatoma 22 cells].
    Biokhimiia (Moscow, Russia), 1992, Volume: 57, Issue:4

    Topics: Animals; Chlorpromazine; Chromatography, Thin Layer; Dexamethasone; Kinetics; Liver Neoplasms, Experimental; Phospholipids; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1992
The murine haemopexin receptor. Evidence that the haemopexin-binding site resides on a 20 kDa subunit and that receptor recycling is regulated by protein kinase C.
    The Biochemical journal, 1991, Jun-01, Volume: 276 ( Pt 2)

    Topics: Animals; Binding Sites; Cell Membrane; Cross-Linking Reagents; Down-Regulation; Endocytosis; Exocytosis; Hemopexin; Kinetics; Liver Neoplasms, Experimental; Macromolecular Substances; Mice; Models, Structural; Molecular Weight; Protein Kinase C; Receptors, Cell Surface; Receptors, Peptide; Tetradecanoylphorbol Acetate

1991
Measurement of the cytosolic Ca2+ mobilization induced by extracellular ATP in AS-30D hepatoma cells using Indo-1.
    Proceedings of the Western Pharmacology Society, 1991, Volume: 34

    Topics: Adenosine Triphosphate; Animals; Calcium; Cytosol; Fluorescence; Indoles; Liver Neoplasms, Experimental; Neoplasm Transplantation; Oxygen Consumption; Rats; Rats, Inbred Strains; Rotenone; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1991
Changes in carboxylesterase isoenzymes of rat liver microsomes during hepatocarcinogenesis.
    Japanese journal of cancer research : Gann, 1991, Volume: 82, Issue:7

    Topics: Animals; Carboxylic Ester Hydrolases; Diglycerides; Enzyme Activation; Hydrogen-Ion Concentration; Isoenzymes; Liver Neoplasms, Experimental; Male; Microsomes, Liver; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate

1991
The level of substrate ornithine can alter polyamine-dependent DNA synthesis following phorbolester stimulation of cultured hepatoma cells.
    Journal of cellular physiology, 1991, Volume: 149, Issue:1

    Topics: Animals; Arginine; Blood; Clone Cells; Culture Media; DNA; Eflornithine; Insulin; Liver Neoplasms, Experimental; Ornithine; Ornithine Decarboxylase; Polyamines; Putrescine; Rats; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1991
Involvement of protein kinase C in the regulation of ornithine decarboxylase mRNA by phorbol esters in rat hepatoma cells.
    Experimental cell research, 1991, Volume: 194, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Diglycerides; Down-Regulation; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Isoquinolines; Liver Neoplasms, Experimental; Ornithine Decarboxylase; Palmitoylcarnitine; Phorbol 12,13-Dibutyrate; Phorbol Esters; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate; Type C Phospholipases

1991
Regulation of ornithine decarboxylase mRNA by phorbol esters and insulin in normal and C-kinase-deficient rat hepatoma cells.
    Journal of cellular physiology, 1991, Volume: 147, Issue:2

    Topics: Animals; Insulin; Kinetics; Liver Neoplasms, Experimental; Ornithine Decarboxylase; Phosphorylation; Protein Kinase C; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1991
Response to IL-6 stimulation of human hepatoblastoma cells: production of pancreatic secretory trypsin inhibitor.
    Biological chemistry Hoppe-Seyler, 1990, Volume: 371 Suppl

    Topics: Animals; Biological Factors; Calcimycin; Colforsin; Cycloheximide; Cytokines; Humans; Interleukin-6; Lipopolysaccharides; Liver Neoplasms, Experimental; Lymphocyte Activation; Tetradecanoylphorbol Acetate; Trypsin Inhibitor, Kazal Pancreatic; Trypsin Inhibitors; Tumor Cells, Cultured

1990
Regulation of Ki-ras expression in Reuber H35 cells.
    European journal of biochemistry, 1990, Nov-13, Volume: 193, Issue:3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Bucladesine; Calcimycin; Calcium; Cell Line; Diglycerides; DNA Probes; Egtazic Acid; Gene Expression Regulation, Neoplastic; Genes, ras; Glucagon; Isoquinolines; Kinetics; Liver Neoplasms, Experimental; Piperazines; Protein Kinase Inhibitors; Rats; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Verapamil

1990
Stimulation of release of Gal beta 1-4GlcNAc alpha 2-6 sialyltransferase from the FAZA hepatoma cell line by dexamethasone and phorbol ester.
    The International journal of biochemistry, 1990, Volume: 22, Issue:1

    Topics: Animals; beta-D-Galactoside alpha 2-6-Sialyltransferase; Dexamethasone; Enzyme Activation; Liver Neoplasms, Experimental; Rats; Sialyltransferases; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1990
Modulation of c-myc gene expression by extracellular stimuli in rat hepatoma cells.
    The Japanese journal of experimental medicine, 1990, Volume: 60, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Blotting, Northern; Concanavalin A; Cycloheximide; Electrophoresis, Polyacrylamide Gel; Gene Expression; Insulin; Insulin Antagonists; Isoquinolines; Liver Neoplasms, Experimental; Piperazines; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myc; Proto-Oncogenes; Rats; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1990
Interaction of insulin and phorbol esters on the regulation of DNA synthesis in rat hepatoma cells.
    Biochemical and biophysical research communications, 1990, Oct-30, Volume: 172, Issue:2

    Topics: Animals; Cell Line; DNA Replication; DNA, Neoplasm; Insulin; Kinetics; Liver Neoplasms, Experimental; Phorbol 12,13-Dibutyrate; Rats; Tetradecanoylphorbol Acetate; Thymidine

1990
Decreased induction of an hepatic mRNA by phorbol esters after insulin desensitization.
    Molecular and cellular endocrinology, 1990, Aug-20, Volume: 72, Issue:2

    Topics: Animals; Cytoplasm; Dexamethasone; Drug Tolerance; Gene Expression Regulation; Insulin; Liver Neoplasms, Experimental; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tubulin; Tumor Cells, Cultured

1990
Embryonic mutation as a possible cause of in utero carcinogenesis in mice revealed by postnatal treatment with 12-O-tetradecanoylphorbol-13-acetate.
    Cancer research, 1990, Apr-01, Volume: 50, Issue:7

    Topics: Animals; Dose-Response Relationship, Radiation; Embryo, Mammalian; Female; Liver Neoplasms, Experimental; Mice; Mutation; Neoplasms, Radiation-Induced; Pregnancy; Skin Neoplasms; Tetradecanoylphorbol Acetate; X-Rays

1990
Differential effects of 12-O-tetradecanoylphorbol 13-acetate on cytochrome P-450-dependent monooxygenase activities in rat hepatoma cells: induction of P-450I and suppression of P-450II.
    Toxicology, 1990, Apr-17, Volume: 61, Issue:2

    Topics: Animals; Antibodies, Monoclonal; Benz(a)Anthracenes; Benzopyrene Hydroxylase; Cell Differentiation; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dexamethasone; Drug Interactions; Enzyme Induction; Liver Neoplasms, Experimental; Mixed Function Oxygenases; Oxidoreductases; Oxygenases; Rats; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1990
Characterization of an endogenous substrate of the insulin receptor in cultured cells.
    The Journal of biological chemistry, 1987, Jul-15, Volume: 262, Issue:20

    Topics: Animals; Cell Line; Cloning, Molecular; Humans; Insulin; Liver Neoplasms, Experimental; Phosphorus Radioisotopes; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Receptor, Insulin; Tetradecanoylphorbol Acetate; Tyrosine

1987
Phorbol ester modulates interleukin 6- and interleukin 1-regulated expression of acute phase plasma proteins in hepatoma cells.
    The Journal of biological chemistry, 1988, Nov-25, Volume: 263, Issue:33

    Topics: Acute-Phase Proteins; Animals; Carcinoma, Hepatocellular; Cell Line; Ethers; Humans; Interleukin-1; Interleukin-6; Interleukins; Ionomycin; Kinetics; Liver Neoplasms; Liver Neoplasms, Experimental; Rats; Recombinant Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic

1988
Beta 1-adrenoceptors in rat hepatoma. Desensitization by isoproterenol and phorbol-myristate-acetate.
    Life sciences, 1989, Volume: 44, Issue:23

    Topics: Adenylyl Cyclases; Animals; Cyclic AMP; Epinephrine; Isoproterenol; Liver; Liver Neoplasms, Experimental; Norepinephrine; Propanolamines; Rats; Receptors, Adrenergic, beta; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1989
Possible involvement of arachidonic acid metabolism in phenobarbital promotion of hepatocarcinogenesis.
    Carcinogenesis, 1989, Volume: 10, Issue:10

    Topics: Acetophenones; Animals; Arachidonic Acid; Arachidonic Acids; Biomarkers, Tumor; Body Weight; Diethylnitrosamine; Ethoxyquin; Flavonoids; gamma-Glutamyltransferase; Liver; Liver Neoplasms, Experimental; Male; Organ Size; Phenobarbital; Quercetin; Rats; Rats, Inbred F344; Tetradecanoylphorbol Acetate

1989
Phorbol ester inhibition of hormonal induction of tyrosine aminotransferase.
    Biochemical and biophysical research communications, 1985, Sep-16, Volume: 131, Issue:2

    Topics: Animals; Bucladesine; Cell Line; Dexamethasone; Dose-Response Relationship, Drug; Enzyme Induction; Insulin; Liver Neoplasms, Experimental; Phorbols; Tetradecanoylphorbol Acetate; Tyrosine Transaminase

1985
Effects of retinoic acid on the transformation and metabolic cooperation of rat liver cells in vitro, and on the growth of hepatoma cells in vivo.
    Carcinogenesis, 1986, Volume: 7, Issue:4

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Drug Synergism; gamma-Glutamyltransferase; Liver; Liver Neoplasms, Experimental; Rats; Rats, Inbred F344; Tetradecanoylphorbol Acetate; Tretinoin

1986
Intercellular communication of transformed and non-transformed rat liver epithelial cells. Modulation by TPA.
    Experimental cell research, 1986, Volume: 165, Issue:2

    Topics: Animals; Cell Communication; Cell Line; Cyclic AMP; Dose-Response Relationship, Drug; Epithelial Cells; Intercellular Junctions; Liver; Liver Neoplasms, Experimental; Phorbols; Rats; Tetradecanoylphorbol Acetate; Time Factors

1986
The effect of phorbol esters and diacylglycerol on expression of the phosphoenolpyruvate carboxykinase (GTP) gene in rat hepatoma H4IIE cells.
    The Journal of biological chemistry, 1986, Dec-25, Volume: 261, Issue:36

    Topics: Animals; Cell Line; Cyclic AMP; Cycloheximide; Dexamethasone; Diglycerides; Genes; Glycerides; Kinetics; Liver Neoplasms, Experimental; Phorbol Esters; Phosphoenolpyruvate Carboxykinase (GTP); Rats; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic

1986
Insulin and phorbol myristic acetate induce ornithine decarboxylase in Reuber H35 rat hepatoma cells by different mechanisms.
    Archives of biochemistry and biophysics, 1988, Nov-01, Volume: 266, Issue:2

    Topics: Animals; Cycloheximide; Dose-Response Relationship, Drug; Enzyme Induction; Insulin; Liver Neoplasms, Experimental; Ornithine Decarboxylase; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured

1988
[Regulation of glucose metabolism by insulin: dual role of protein kinase C].
    Annales d'endocrinologie, 1988, Volume: 49, Issue:4-5

    Topics: Adipose Tissue; Animals; Biological Transport; Calcium; Deoxyglucose; Dinitrophenols; Glucose; Insulin; Liver Neoplasms, Experimental; Melitten; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate

1988
Contrasting interactions between phorbol ester and insulin on the regulation of glycogen synthase activity and p33 mRNA accumulation in rat hepatoma cells.
    Archives of biochemistry and biophysics, 1988, Volume: 260, Issue:1

    Topics: Animals; Cell Line; Dactinomycin; Drug Interactions; Drug Synergism; Glycogen Synthase; Insulin; Liver Neoplasms, Experimental; Phorbol Esters; Phosphorylation; Rats; Receptor, Insulin; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate

1988
Phorbol ester-induced serine phosphorylation of the insulin receptor decreases its tyrosine kinase activity.
    The Journal of biological chemistry, 1988, Mar-05, Volume: 263, Issue:7

    Topics: Adenosine Triphosphate; Alkaline Phosphatase; Animals; Chromatography, Affinity; Insulin; Liver Neoplasms, Experimental; Phosphorylation; Phosphoserine; Phosphothreonine; Protein-Tyrosine Kinases; Rats; Receptor, Insulin; Serine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine

1988
Insulin- and phorbol ester-stimulated phosphorylation of ribosomal protein S6.
    The Journal of biological chemistry, 1985, Mar-10, Volume: 260, Issue:5

    Topics: Animals; Cell Line; Insulin; Liver Neoplasms, Experimental; Peptide Hydrolases; Phorbols; Phosphorylation; Protein Kinase C; Protein Kinases; Rats; Ribosomal Protein S6; Ribosomal Proteins; Tetradecanoylphorbol Acetate; Trypsin

1985
Effect of protein kinase C activation and depletion on insulin stimulation of glycogen synthesis in cultured hepatoma cells.
    Experientia, 1988, Jan-15, Volume: 44, Issue:1

    Topics: Animals; Enzyme Activation; Glycogen; Insulin; Liver Neoplasms, Experimental; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1988
Transcriptional regulation of a rat hepatoma gene by insulin and protein kinase-C.
    Endocrinology, 1988, Volume: 123, Issue:1

    Topics: Animals; Cell Nucleus; Gene Expression Regulation; Insulin; Kinetics; Liver Neoplasms, Experimental; Protein Kinase C; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic

1988
Insulin as a growth factor in rat hepatoma cells. Stimulation of proto-oncogene expression.
    The Journal of biological chemistry, 1987, Aug-05, Volume: 262, Issue:22

    Topics: Actins; Animals; Blood; Cell Line; DNA; Growth Substances; Insulin; Liver Neoplasms, Experimental; Oncogenes; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic

1987
Positive interaction between insulin and phorbol esters on the regulation of a specific messenger ribonucleic acid in rat hepatoma cells.
    Endocrinology, 1987, Volume: 121, Issue:4

    Topics: Animals; Cell Line; Drug Interactions; Drug Stability; Insulin; Liver Neoplasms, Experimental; Osmolar Concentration; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors

1987
Insulin action in normal and protein kinase C-deficient rat hepatoma cells. Effects on protein phosphorylation, protein kinase activities, and ornithine decarboxylase activities and messenger ribonucleic acid levels.
    Molecular endocrinology (Baltimore, Md.), 1987, Volume: 1, Issue:1

    Topics: Animals; Insulin; Liver; Liver Neoplasms, Experimental; Ornithine Decarboxylase; Phorbol Esters; Phosphorylation; Protein Kinase C; Protein Kinases; Rats; Ribosomal Protein S6; Ribosomal Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1987
Increased ornithine decarboxylase activity in cultured cells exposed to low energy modulated microwave fields and phorbol ester tumor promoters.
    Cancer research, 1988, Aug-01, Volume: 48, Issue:15

    Topics: Animals; Cells, Cultured; Cricetinae; Cricetulus; Liver Neoplasms, Experimental; Melanoma; Microwaves; Ornithine Decarboxylase; Phorbol Esters; Tetradecanoylphorbol Acetate

1988
Enhancing effect of a phorbol ester and of retinoic acid on glucocorticoid induction of chenodeoxycholate hydroxylation in hepatoma cultures.
    European journal of biochemistry, 1988, Aug-15, Volume: 175, Issue:3

    Topics: Animals; Benzopyrene Hydroxylase; Biotransformation; Cells, Cultured; Chenodeoxycholic Acid; Cytochrome P-450 Enzyme System; Dexamethasone; Drug Synergism; Enzyme Induction; Hydroxylation; Liver Neoplasms, Experimental; Tetradecanoylphorbol Acetate; Tretinoin

1988
[The use of a primary culture of liver cells from rat embryos subjected to transplacental exposure to N-nitrosodiethylamine for the study of hepatocarcinogenesis promoters].
    Eksperimental'naia onkologiia, 1987, Volume: 9, Issue:6

    Topics: Animals; Carcinogens; Cells, Cultured; Cocarcinogenesis; Diethylnitrosamine; Female; Liver; Liver Neoplasms, Experimental; Phenobarbital; Rats; Tetradecanoylphorbol Acetate

1987
Phosphorylation of histones is stimulated by phorbol esters in quiescent Reuber H35 hepatoma cells.
    The Journal of biological chemistry, 1986, Jul-15, Volume: 261, Issue:20

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine Diphosphate Ribose; Alkaline Phosphatase; Animals; Cell Line; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Histones; Insulin; Liver Neoplasms, Experimental; Phorbols; Phosphates; Phosphorus Radioisotopes; Phosphorylation; Rats; Tetradecanoylphorbol Acetate

1986
Potentiation of specific association of insulin with HepG2 cells by phorbol esters.
    The Biochemical journal, 1986, May-15, Volume: 236, Issue:1

    Topics: Animals; Cell Line; Chloroquine; Drug Synergism; Humans; Insulin; Liver Neoplasms, Experimental; Monensin; Phorbol Esters; Phospholipases; Protein Binding; Tetradecanoylphorbol Acetate

1986
Transient induction of ornithine decarboxylase mRNA in rat hepatoma cells treated with 12-O-tetradecanoylphorbol-13-acetate.
    Biochemical and biophysical research communications, 1987, Sep-15, Volume: 147, Issue:2

    Topics: Animals; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Kinetics; Liver Neoplasms, Experimental; Nucleic Acid Hybridization; Ornithine Decarboxylase; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic

1987
Ca2+-dependent cell surface protein phosphorylation may be involved in the initiation of DNA synthesis.
    Journal of cellular physiology, 1986, Volume: 129, Issue:3

    Topics: Adenosine Triphosphate; Animals; Calcium; Cell Division; Cell Line; DNA; Liver; Liver Neoplasms, Experimental; Membrane Proteins; Phosphoproteins; Phosphorylation; Protein Kinases; Rats; Tetradecanoylphorbol Acetate; Trypsin

1986