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tetradecanoylphorbol acetate and Disease Exacerbation

tetradecanoylphorbol acetate has been researched along with Disease Exacerbation in 79 studies

Research

Studies (79)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's12 (15.19)18.2507
2000's39 (49.37)29.6817
2010's27 (34.18)24.3611
2020's1 (1.27)2.80

Authors

AuthorsStudies
Ding, ZD; Fu, YJ; Jiang, YJ; Shang, H; Song, CB; Xu, JJ; Zhang, ZN; Zheng, JF1
Dahlhoff, M; Fröhlich, T; Goebeler, M; Hoesl, C; Hundt, JE; Kneitz, H; Schneider, MR; Wolf, R1
Fukui, H; Kobayashi, M; Mizuguchi, H; Sato, Y; Tamaki, M; Tokashiki, N; Yamamoto, K; Yamauchi, A1
Christensen, R; Füchtbauer, AC; Füchtbauer, EM; Gunnarsson, A; Jensen, UB; Owens, DM; Ramsing, M1
Anguish, LJ; Coonrod, SA; Horibata, S; McElwee, JL; McLean, D; Mohanan, S; Mukai, C; Sams, K; Yan, A1
Chen, JK; Chu, WK; Dai, PM; Li, HL; Pao, CC1
Bougiouklis, D; Chatzizisi, O; Diza-Mataftsi, E; Gounari, E; Iakovidis, D; Kontakiotis, T; Kyriazis, G; Markopoulou, A; Papakosta, D; Serasli, E; Zoglopitis, F1
Aoto, Y; Goitsuka, R; Hachiya, T; Hirose, S; Isogai, E; Katsuragi, Y; Kominami, R; Nakamura, T; Okumura, K; Saito, M; Sakakibara, Y; Wakabayashi, Y1
Athar, M; Cochran, JB; Elmets, CA; McKay, KM; Nasti, TH; Timares, L; Tsuruta, Y; Yusuf, N1
Bao, R; Bechill, J; Bindokas, VP; Faber, PW; Lingen, MW; Spiotto, MT; Zhong, R1
Davison, G; Izzat, HJ; Jones, AW; Lewis, KE; Mohamed, P; Robinson, R1
Davidson, B; Flørenes, VA; Jørgensen, K; Rosnes, AK; Skrede, M; Slipicevic, A; Trøen, G1
Chandler, PR; Duhadaway, JB; Everhart, ME; Johnson, BA; Kahler, DJ; Mellor, AL; Muller, AJ; Munn, DH; Pihkala, J; Prendergast, GC; Sharma, MD; Soler, AP1
Fujiki, H; Suganuma, M1
Arbeit, JM; Kladney, RD; Martin, RJ; Neumann, RG; Scortegagna, M1
Chao, SC; Hu, DN; Lin, CY; Yang, PY; Yang, SF; Ye, YZ1
Arthur, JS; Burns, CJ; Efimova, T; Gribben, EL; Hindes, A; Kissling, GE; Lin, MH; Longmore, GD; Owen, RJ; Schindler, EM; Yin, Y1
Andersen, O; Bergström, T; Hellstrand, K; Mossberg, N; Movitz, C; Nilsson, S1
Gaestel, M; Iversen, L; Johansen, C; Kollias, G; Kragballe, K; Vestergaard, C1
Fischer, SM; Herschman, HR; Huang, SC; Ishikawa, TO; Kumar, IP; Kusewitt, D; Machado, HB; Wong, KP1
Chang, EI; Ikonomidis, JS; Jones, JA; Koval, C; Sheats, N; Spinale, FG; Stroud, RE; Zavadzkas, JA1
Glick, AB; Kennett, MJ; Masiuk, KE; Mordasky Markell, L; Pérez-Lorenzo, R1
Aboodi, GM; Glogauer, M; Goldberg, MB1
Akakura, S; Bouchard, R; Bshara, W; Gelman, IH; Morrison, C1
Abel, E; Fischer, SM; Mikulec, C; Pavone, A; Rundhaug, J; Surh, I1
Jin, JY; Leshin, B; Lutfeali, S; Miliani de Marval, P; Selim, MA; Zhang, JY1
Buchl, S; He, H; Nehete, B; Nehete, PN; Sastry, KJ; Wieder, E; Yang, G1
Chang, TY; Cheng, CC; Hu, CT; Lee, MC; Pan, SM; Wang, HT; Wang, LJ; Wang, S; Wu, JR; Wu, WS1
Abecasis, R; Billordo, LA; Cherñavsky, AC; Ferreyra Solari, NE; Gadano, AC; Inzaugarat, ME1
Chaiswing, L; Dhar, SK; Oberley, TD; St Clair, DK; Tangpong, J1
Bendt, KM; Edwards, RH; Moore, DT; Nielsen, JN; Raab-Traub, N; Shair, KH1
da Rocha, LF; Dantas, AT; Duarte, ÂL; Galdino, SL; Mariz, HA; Pitta, Ida R; Pitta, MG1
Guo, X; Kimura, S; Sasaguri, Y; Shimajiri, S; Tanimoto, A; Tasaki, T; Wang, KY; Yamada, S1
Chang, Y; Chen, JY; Chou, SP; Fang, CY; Hsu, HY; Huang, SY; Takada, K; Tsai, CH; Wu, CC1
Azorsa, DO; Byron, SA; Hostetter, G; Kim, S; Little, TH; Min, E; Tapia, C; Thal, TS; Watanabe, AT1
Braeuning, A; Münzel, PA; Schwarz, M1
Ho, YS; Lee, WS; Liang, YC; Lin, SY; Pan, S; Tsai, SH1
Ichiishi, E; Ishikawa, T; Kokura, S; Kuchide, M; Naito, Y; Nishino, H; Tokuda, H; Toyokuni, S; Yoshida, N; Yoshikawa, T1
Athar, M; Bhasin, G; Kauser, H1
Aguilar, M; Garcia del Moral, R; Martín-Oliva, D; Muñoz-Gámez, JA; Nuñez, MI; O'Valle, F; Oliver, FJ; Ruiz de Almodóvar, JM; Valenzuela, MT1
Balmain, A; Del Rosario, R; Mao, JH; Perez-Losada, J; To, MD; Wu, D1
Pallister, I; Topley, N1
Bottaro, DP; Burke, TR; Gao, Y; Ishibashi, T; Liu, N; Soriano, JV; Underhill, C; Yao, ZJ1
Cruciani, V; Flørenes, VA; Jørgensen, K; Mikalsen, SO; Skrede, M; Slipicevic, A1
Adiseshaiah, P; Kalvakolanu, DV; Peddakama, S; Reddy, SP; Zhang, Q1
Bassi, DE; Cenna, J; Cukierman, E; Klein-Szanto, AJ; Litwin, S; Lopez De Cicco, R1
Hsiang, CH; Ornstein, DK; Tunoda, T; Tyson, DR; Whang, YE1
Chan, EL; Collins, MH; Kader, SA; Pathrose, P; Peace, BE; Toney, K; Waltz, SE1
Abel, E; Beltran, L; Carbajal, S; Chan, KS; Clifford, J; Digiovanni, J; Kataoka, K; Peavey, M; Sano, S; Shen, J1
Kim, Y; Klein-Szanto, A; Macias, E; Miliani de Marval, PL; Rodriguez-Puebla, ML1
Arabzadeh, A; Troy, TC; Turksen, K1
Cline, JM; Lorenzo, PS; Luke, CT; Oki-Idouchi, CE1
Brown, KA; Chand, AL; Clyne, CD; Knower, KC; McInnes, KJ; Simpson, ER1
Baker, AR; Colburn, NH; Hagan, JP; Hegamyer, G; Jansen, AP; Schmid, T1
Griffin, T; Hohberger, L; Ondrey, F; Wuertz, BR; Xie, H1
Bartkowiak, J; Hyjek, E; Hyslop, T; Kozbor, D; Kubin, M; Lischner, HW; Trinchieri, G1
Benedetto, A; Delfini, C; Di Caro, A; Di Sora, F; Garbuglia, AR; Montella, F; Recchia, O; Salvi, R1
Fürstenberger, G; Kopp-Schneider, A1
Adány, R; Karányi, Z; Kávai, M; Kertai, P; Pocsai, Z; Szucs, S; Varga, C1
Cano, A; Conti, CJ; Duran, H; Jorcano, JL; Larcher, F; Murillas, R; Quintanilla, M; Robles, AI1
Honn, KV; Trikha, M1
Kerman, RH; Lindsey, JW; Wolinsky, JS1
Darwiche, N; De Luca, LM; Gartsbein, M; Hansen, L; Hennings, H; Lowry, D; Morgan, DL; Tennenbaum, T; Yuspa, SH1
Birkedal-Hansen, H; Havemose-Poulsen, A; Holmstrup, P; Stoltze, K1
Brinkley, BR; Greenhalgh, DA; He, D; Jiang, A; Roop, DR; Wang, XJ; Zhong, L1
Deng, C; Fernandez-Salas, E; Hennings, H; Mirosh, E; Morgan, DL; Shalizi, A; Stanulis, E; Weinberg, WC; Yuspa, SH1
Fischer, SM; La, E; Locniskar, MF; Muga, SJ1
Lambert, PF; Liem, A; Miller, JA; Song, S1
Benavides, F; Conti, CJ; Klingelberger, EA; Stern, MC1
Gotoh, A; Keller, ET; Matsumoto, T; Mizokami, A; Yamada, H1
Gaiotti, D; Hansen, L; Michael, E; Nees, M; Woodworth, CD1
Beltrán, L; Bol, D; Carbajal, S; Chan, K; DiGiovanni, J; Jorcano, J; Kiguchi, K; Moats, S1
Dreckschmidt, NE; Jansen, AP; Oberley, TD; Verma, AK; Verwiebe, EG; Wheeler, DL1
Fang, D; Hallman, J; Hammarback, JA; Kute, TE; Sangha, N; Setaluri, V; White, WL1
Febbraio, M; Hajjar, DP; Han, J; Nicholson, AC; Silversterin, RL1
Chen, D; Namba, H; Nishizawa, S; Ohta, S; Yokota, N; Yokoyama, T1
Birt, DF; Hawley, J; Liu, Y; Wang, W1
Clark, K; Collard, JG; Malliri, A; Michiels, F; van der Kammen, RA; van der Valk, M1
Angel, P; Breitenbach, U; Dittrich, BT; Gebhardt, C; Richter, KH; Tuckermann, JP1

Reviews

4 review(s) available for tetradecanoylphorbol acetate and Disease Exacerbation

ArticleYear
Carcinogenic aspects of protein phosphatase 1 and 2A inhibitors.
    Progress in molecular and subcellular biology, 2009, Volume: 46

    Topics: Animals; Carcinogens; Disease Progression; Enzyme Inhibitors; Humans; Marine Toxins; Mice; Models, Molecular; Neoplasms; Neoplasms, Experimental; Okadaic Acid; Oxazoles; Protein Phosphatase 1; Protein Phosphatase 2; Rats; Skin Neoplasms; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

2009
Non-melanoma skin cancer in mouse and man.
    Archives of toxicology, 2013, Volume: 87, Issue:5

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Disease Models, Animal; Disease Progression; Genes, p53; Genes, ras; Humans; Melanoma; Mice; Mutation; Neoplasm Invasiveness; Neoplastic Stem Cells; Papilloma; Risk Assessment; Skin; Skin Neoplasms; Species Specificity; Tetradecanoylphorbol Acetate

2013
Role of 12-lipoxygenase and protein kinase C in modulating the activation state of the integrin alpha IIb beta 3 on human tumor cells.
    Advances in experimental medicine and biology, 1997, Volume: 407

    Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Arachidonate 12-Lipoxygenase; Cell Adhesion; Cell Movement; Disease Progression; Enzyme Activation; Extracellular Matrix; Humans; Models, Biological; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Proteins; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1997
Role of CD36, the macrophage class B scavenger receptor, in atherosclerosis.
    Annals of the New York Academy of Sciences, 2001, Volume: 947

    Topics: Arteriosclerosis; CD36 Antigens; Disease Progression; Foam Cells; Gene Expression Regulation; Humans; Lipoproteins, LDL; Macrophages; Membrane Proteins; Receptors, Cytoplasmic and Nuclear; Receptors, Immunologic; Receptors, Lipoprotein; Receptors, Scavenger; Scavenger Receptors, Class B; Tetradecanoylphorbol Acetate; Transcription Factors; Transcription, Genetic

2001

Other Studies

75 other study(ies) available for tetradecanoylphorbol acetate and Disease Exacerbation

ArticleYear
Decreased CD4
    Cytokine, 2020, Volume: 125

    Topics: Adult; Biomarkers; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Chronic Disease; Correlation of Data; Disease Progression; HIV Infections; HIV-1; Humans; Interferon-gamma; Male; Tetradecanoylphorbol Acetate; Viral Load

2020
The transmembrane protein LRIG2 increases tumor progression in skin carcinogenesis.
    Molecular oncology, 2019, Volume: 13, Issue:11

    Topics: Aged; Aged, 80 and over; Animals; Carcinogenesis; Cell Differentiation; Cell Line, Tumor; Disease Progression; Epidermis; ErbB Receptors; Homeostasis; Humans; Hyperplasia; Inflammation; Membrane Glycoproteins; Mice, Inbred C57BL; Phenotype; Protein Binding; Skin Neoplasms; Tetradecanoylphorbol Acetate; Thrombospondins

2019
Protein kinase C-δ signaling regulates glucagon secretion from pancreatic islets.
    The journal of medical investigation : JMI, 2017, Volume: 64, Issue:1.2

    Topics: Animals; Diabetes Mellitus, Experimental; Disease Progression; Glucagon; Humans; In Vitro Techniques; Islets of Langerhans; Male; Mice; Mice, Inbred C57BL; Phosphorylation; Protein Kinase C-delta; Quercetin; Signal Transduction; Tetradecanoylphorbol Acetate

2017
Constitutive transgene expression of Stem Cell Antigen-1 in the hair follicle alters the sensitivity to tumor formation and progression.
    Stem cell research, 2017, Volume: 23

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Ly; Carcinogenesis; Clone Cells; Colony-Forming Units Assay; Disease Progression; Female; Hair Follicle; Integrases; Membrane Proteins; Mice, Inbred C57BL; Mice, Transgenic; Morphogenesis; Skin; Tetradecanoylphorbol Acetate; Transgenes

2017
PAD2 overexpression in transgenic mice augments malignancy and tumor-associated inflammation in chemically initiated skin tumors.
    Cell and tissue research, 2017, Volume: 370, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogenesis; Carcinogens; Disease Progression; Gene Expression Regulation, Neoplastic; Humans; Inflammation; Male; Mice; Mice, Transgenic; Papilloma; Protein-Arginine Deiminase Type 2; Protein-Arginine Deiminases; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Up-Regulation

2017
Nanog expression is negatively regulated by protein kinase C activities in human cancer cell lines.
    Carcinogenesis, 2013, Volume: 34, Issue:7

    Topics: Carcinoma; Cell Proliferation; Disease Progression; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Gene Silencing; Hep G2 Cells; Homeodomain Proteins; Humans; Isoenzymes; Mutagenesis, Site-Directed; Nanog Homeobox Protein; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Octamer Transcription Factor-3; Promoter Regions, Genetic; Protein Kinase C-alpha; Protein Kinase C-delta; RNA, Messenger; SOXB1 Transcription Factors; Tetradecanoylphorbol Acetate; Transcription, Genetic

2013
Potential prognostic value of intracellular cytokine detection by flow cytometry in pulmonary sarcoidosis.
    Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, 2013, Volume: 33, Issue:5

    Topics: Adult; Aged; Biomarkers; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Separation; Cytokines; Disease Progression; Flow Cytometry; Humans; Inflammation Mediators; Ionomycin; Lung; Lymphocyte Activation; Middle Aged; Prognosis; Radiography; Sarcoidosis, Pulmonary; Tetradecanoylphorbol Acetate; Th1-Th2 Balance; Young Adult

2013
Meis1 regulates epidermal stem cells and is required for skin tumorigenesis.
    PloS one, 2014, Volume: 9, Issue:7

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adult Stem Cells; Animals; Carcinogens; Carcinoma; Cell Differentiation; Cell Proliferation; Cell Transformation, Neoplastic; Disease Progression; Gene Expression Regulation, Neoplastic; Hair Follicle; Homeodomain Proteins; Keratinocytes; Mice; Mice, Transgenic; Multipotent Stem Cells; Myeloid Ecotropic Viral Integration Site 1 Protein; Neoplasm Proteins; Papilloma; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate

2014
A murine model for the development of melanocytic nevi and their progression to melanoma.
    Molecular carcinogenesis, 2016, Volume: 55, Issue:5

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Line, Tumor; Cell Separation; Cyclin-Dependent Kinase Inhibitor p16; Disease Models, Animal; Disease Progression; Melanoma; Mice; Mice, Nude; Mutation; Neoplasm Proteins; Nevus, Pigmented; ras Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate

2016
Notch1 Activation or Loss Promotes HPV-Induced Oral Tumorigenesis.
    Cancer research, 2015, Sep-15, Volume: 75, Issue:18

    Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Carcinogens; Carcinoma, Verrucous; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cocarcinogenesis; Disease Progression; DNA Transposable Elements; Female; Humans; Mice; Mice, Transgenic; Mouth Neoplasms; Mutagenesis, Insertional; Neoplasm Invasiveness; Oncogenes; Papilloma; Papillomaviridae; Receptor, Notch1; Skin Neoplasms; Specific Pathogen-Free Organisms; Tamoxifen; Tetradecanoylphorbol Acetate; Tumor Virus Infections; Uterine Cervical Neoplasms

2015
Impaired Blood Neutrophil Function in the Frequent Exacerbator of Chronic Obstructive Pulmonary Disease: A Proof-of-Concept Study.
    Lung, 2016, Volume: 194, Issue:6

    Topics: Aged; Case-Control Studies; Cell Degranulation; Disease Progression; Female; Humans; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Proof of Concept Study; Pulmonary Disease, Chronic Obstructive; Respiratory Burst; Symptom Flare Up; Tetradecanoylphorbol Acetate

2016
The fatty acid binding protein 7 (FABP7) is involved in proliferation and invasion of melanoma cells.
    BMC cancer, 2008, Sep-30, Volume: 8

    Topics: Biomarkers, Tumor; Carcinogens; Carrier Proteins; Cell Nucleus; Cell Proliferation; Cytoplasm; Disease Progression; Enzyme Inhibitors; Fatty Acid-Binding Protein 7; Flavonoids; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Immunoblotting; Immunoenzyme Techniques; Melanoma; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neoplasm Invasiveness; Nevus, Pigmented; Oligonucleotide Array Sequence Analysis; Prognosis; RNA, Messenger; RNA, Small Interfering; Skin Neoplasms; Survival Rate; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Suppressor Proteins

2008
Chronic inflammation that facilitates tumor progression creates local immune suppression by inducing indoleamine 2,3 dioxygenase.
    Proceedings of the National Academy of Sciences of the United States of America, 2008, Nov-04, Volume: 105, Issue:44

    Topics: Animals; Dendritic Cells; Dermatitis, Contact; Disease Progression; Immune Tolerance; Indoleamine-Pyrrole 2,3,-Dioxygenase; Lymph Nodes; Mice; Mice, Inbred C57BL; Models, Animal; Papilloma; Signal Transduction; Skin Neoplasms; T-Lymphocytes; Tetradecanoylphorbol Acetate

2008
Hypoxia-inducible factor-1alpha suppresses squamous carcinogenic progression and epithelial-mesenchymal transition.
    Cancer research, 2009, Mar-15, Volume: 69, Issue:6

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Cycle Proteins; Disease Progression; Epithelial Cells; Hypoxia-Inducible Factor 1, alpha Subunit; Intracellular Signaling Peptides and Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Selenium-Binding Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transfection

2009
Increased expression of gelatinase (MMP-2 and MMP-9) in pterygia and pterygium fibroblasts with disease progression and activation of protein kinase C.
    Investigative ophthalmology & visual science, 2009, Volume: 50, Issue:10

    Topics: Cells, Cultured; Conjunctiva; Disease Progression; Enzyme Activation; Female; Fibroblasts; Gene Expression Regulation, Enzymologic; Humans; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Middle Aged; Protein Kinase C; Pterygium; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetradecanoylphorbol Acetate

2009
p38delta Mitogen-activated protein kinase is essential for skin tumor development in mice.
    Cancer research, 2009, Jun-01, Volume: 69, Issue:11

    Topics: Animals; Animals, Newborn; Carcinoma; Cell Proliferation; Disease Progression; Epidermis; Female; Genes, ras; Genotype; Hyperplasia; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinase 13; Mutation; Skin Neoplasms; Tetradecanoylphorbol Acetate

2009
Oxygen radical production in leukocytes and disease severity in multiple sclerosis.
    Journal of neuroimmunology, 2009, Aug-18, Volume: 213, Issue:1-2

    Topics: Autoimmunity; Cytoprotection; Disease Progression; Female; Humans; Inflammation Mediators; Leukocytes; Male; Middle Aged; Multiple Sclerosis; NADPH Oxidases; Oligopeptides; Oxidative Stress; Phagocytes; Reactive Oxygen Species; Respiratory Burst; Severity of Illness Index; Superoxides; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

2009
MK2 regulates the early stages of skin tumor promotion.
    Carcinogenesis, 2009, Volume: 30, Issue:12

    Topics: Animals; Apoptosis; Disease Progression; DNA Damage; Gene Expression Regulation, Neoplastic; Inflammation; Intracellular Signaling Peptides and Proteins; Keratinocytes; Mice; Mice, Transgenic; Phosphorylation; Protein Serine-Threonine Kinases; RNA, Small Interfering; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Tumor Suppressor Protein p53

2009
Positron emission tomography imaging of DMBA/TPA mouse skin multi-step tumorigenesis.
    Molecular oncology, 2010, Volume: 4, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Disease Progression; Female; Fluorodeoxyglucose F18; Glucose; Mice; Papilloma; Positron-Emission Tomography; Predictive Value of Tests; Radiopharmaceuticals; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tomography, X-Ray Computed

2010
Cellular phenotype transformation occurs during thoracic aortic aneurysm development.
    The Journal of thoracic and cardiovascular surgery, 2010, Volume: 140, Issue:3

    Topics: Angiotensin II; Animals; Aorta, Thoracic; Aortic Aneurysm, Thoracic; Calcium Chloride; Cells, Cultured; Disease Models, Animal; Disease Progression; Endothelin-1; Extracellular Matrix Proteins; Female; Fibroblasts; Gene Expression Profiling; Gene Expression Regulation; Genotype; Male; Mice; Mice, Inbred C57BL; Phenotype; Reverse Transcriptase Polymerase Chain Reaction; Tetradecanoylphorbol Acetate

2010
Use of a TGFbeta type I receptor inhibitor in mouse skin carcinogenesis reveals a dual role for TGFbeta signaling in tumor promotion and progression.
    Carcinogenesis, 2010, Volume: 31, Issue:12

    Topics: Animals; Benzamides; Dioxoles; Disease Progression; Genes, ras; Mice; Papilloma; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Signal Transduction; Skin Neoplasms; Smad2 Protein; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta1

2010
Refractory periodontitis population characterized by a hyperactive oral neutrophil phenotype.
    Journal of periodontology, 2011, Volume: 82, Issue:5

    Topics: Adult; Aged; Dental Plaque Index; Disease Progression; Female; Flow Cytometry; Fluorescent Dyes; Follow-Up Studies; Furcation Defects; Gingival Hemorrhage; Gingival Recession; Humans; Leukocyte Count; Male; Middle Aged; Mouth Mucosa; Neutrophil Activation; Neutrophils; Periodontal Attachment Loss; Periodontal Pocket; Periodontitis; Phenotype; Reactive Oxygen Species; Rhodamines; Tetradecanoylphorbol Acetate; Tooth Mobility

2011
Carcinogen-induced squamous papillomas and oncogenic progression in the absence of the SSeCKS/AKAP12 metastasis suppressor correlate with FAK upregulation.
    International journal of cancer, 2011, Oct-15, Volume: 129, Issue:8

    Topics: 9,10-Dimethyl-1,2-benzanthracene; A Kinase Anchor Proteins; Animals; Cell Cycle Proteins; Disease Progression; Focal Adhesion Kinase 1; Gene Expression Regulation, Neoplastic; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Up-Regulation

2011
Upregulation of the EP1 receptor for prostaglandin E2 promotes skin tumor progression.
    Molecular carcinogenesis, 2011, Volume: 50, Issue:6

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Blotting, Western; Carcinogens; Cell Proliferation; Cyclooxygenase 2; Dinoprostone; Disease Progression; Epidermis; Female; Humans; Mice; Mice, Hairless; Mice, Transgenic; Receptors, Prostaglandin E, EP1 Subtype; Skin Neoplasms; Tetradecanoylphorbol Acetate; Ultraviolet Rays; Up-Regulation

2011
CYLD inhibits tumorigenesis and metastasis by blocking JNK/AP1 signaling at multiple levels.
    Cancer prevention research (Philadelphia, Pa.), 2011, Volume: 4, Issue:6

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Cysteine Endopeptidases; Deubiquitinating Enzyme CYLD; Disease Progression; Epidermal Cells; Epidermis; Humans; Hyperplasia; Immunoblotting; Immunoprecipitation; JNK Mitogen-Activated Protein Kinases; Lymphatic Metastasis; Mice; Mice, Transgenic; Mutation; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Tumor Cells, Cultured; Tumor Suppressor Proteins; Ubiquitination

2011
Functional impairment of central memory CD4 T cells is a potential early prognostic marker for changing viral load in SHIV-infected rhesus macaques.
    PloS one, 2011, Volume: 6, Issue:5

    Topics: Animals; Biomarkers; CD4-Positive T-Lymphocytes; Chronic Disease; Cytokines; Disease Progression; Humans; Immunologic Memory; Ionomycin; Macaca mulatta; Prognosis; Simian Acquired Immunodeficiency Syndrome; Tetradecanoylphorbol Acetate; Viral Load; Viremia

2011
Reactive oxygen species-mediated PKC and integrin signaling promotes tumor progression of human hepatoma HepG2.
    Clinical & experimental metastasis, 2011, Volume: 28, Issue:8

    Topics: Animals; Blotting, Western; Carcinoma, Hepatocellular; Cell Movement; Disease Progression; Extracellular Signal-Regulated MAP Kinases; Fluorescent Antibody Technique; Humans; Integrins; Liver Neoplasms; Male; Mice; Mice, Inbred NOD; Mice, SCID; Protein Kinase C-alpha; Reactive Oxygen Species; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

2011
Altered phenotype and functionality of circulating immune cells characterize adult patients with nonalcoholic steatohepatitis.
    Journal of clinical immunology, 2011, Volume: 31, Issue:6

    Topics: Adult; Aged; CD4 Antigens; CD8 Antigens; Cells, Cultured; Disease Progression; Fatty Liver; Female; Fibrosis; Gene Expression Regulation; Humans; Immunophenotyping; Interferon-gamma; Leukocyte Common Antigens; Liver; Male; Middle Aged; Monocytes; Neutrophils; Oxidative Stress; Reactive Oxygen Species; T-Lymphocytes; Tetradecanoylphorbol Acetate; Th1-Th2 Balance

2011
Manganese superoxide dismutase is a p53-regulated gene that switches cancers between early and advanced stages.
    Cancer research, 2011, Nov-01, Volume: 71, Issue:21

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Cocarcinogenesis; Disease Progression; Enhancer Elements, Genetic; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Genes, Reporter; Genes, Synthetic; Humans; Mice; Mice, Transgenic; Neoplasm Proteins; Papilloma; Promoter Regions, Genetic; Recombinant Fusion Proteins; Skin Neoplasms; Sp1 Transcription Factor; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Suppressor Protein p53

2011
Epstein-Barr virus-encoded latent membrane protein 1 (LMP1) and LMP2A function cooperatively to promote carcinoma development in a mouse carcinogenesis model.
    Journal of virology, 2012, Volume: 86, Issue:9

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma; Cell Transformation, Viral; Disease Models, Animal; Disease Progression; Gene Expression; Genes, ras; Keratin-14; Mice; Mice, Inbred BALB C; Mice, Transgenic; Mutation; Papilloma; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Viral Matrix Proteins

2012
Increased serum interleukin 22 in patients with rheumatoid arthritis and correlation with disease activity.
    The Journal of rheumatology, 2012, Volume: 39, Issue:7

    Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Calcium Ionophores; Carcinogens; Cells, Cultured; Disease Progression; Female; Humans; Interleukin-22; Interleukins; Ionomycin; Leukocytes, Mononuclear; Male; Middle Aged; Osteolysis; Rheumatoid Factor; Severity of Illness Index; Tetradecanoylphorbol Acetate

2012
Expression of macrophage-derived chemokine (CCL22) in atherosclerosis and regulation by histamine via the H2 receptor.
    Pathology international, 2012, Volume: 62, Issue:10

    Topics: Aorta; Atherosclerosis; Cell Line, Tumor; Cell Movement; Chemokine CCL22; Chemokines; Dendritic Cells; Disease Progression; Gene Expression Regulation; Histamine; Humans; Leukocytes, Mononuclear; Macrophages; Models, Molecular; Monocytes; Myocardial Ischemia; Promoter Regions, Genetic; Receptors, Histamine H2; Tetradecanoylphorbol Acetate

2012
The synergistic effect of chemical carcinogens enhances Epstein-Barr virus reactivation and tumor progression of nasopharyngeal carcinoma cells.
    PloS one, 2012, Volume: 7, Issue:9

    Topics: Animals; Butyrates; Carcinogens; Carcinoma; Cell Line, Tumor; Cell Transformation, Viral; Disease Progression; Drug Synergism; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genome, Human; Genomic Instability; Herpesvirus 4, Human; Humans; Methylnitronitrosoguanidine; Mice; Mice, SCID; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplasm Invasiveness; Tetradecanoylphorbol Acetate; Virus Activation

2012
Negative regulation of NF-κB by the ING4 tumor suppressor in breast cancer.
    PloS one, 2012, Volume: 7, Issue:10

    Topics: Antibodies, Monoclonal; Breast Neoplasms; Cell Cycle Proteins; Cell Line, Tumor; Disease Progression; Disease-Free Survival; Down-Regulation; Homeodomain Proteins; Humans; Neoplasm Invasiveness; Phosphorylation; Tetradecanoylphorbol Acetate; Transcription Factor RelA; Transcription, Genetic; Tumor Suppressor Proteins

2012
Involvement of both extracellular signal-regulated kinase and c-jun N-terminal kinase pathways in the 12-O-tetradecanoylphorbol-13-acetate-induced upregulation of p21(Cip1) in colon cancer cells.
    Molecular carcinogenesis, 2002, Volume: 35, Issue:1

    Topics: Adenocarcinoma; CDC2-CDC28 Kinases; Cell Cycle; Cell Division; Chromosome Mapping; Colonic Neoplasms; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinases; Cyclins; Disease Progression; Enzyme Inhibitors; Flavonoids; Humans; Imidazoles; Isoenzymes; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases; Protein Kinase C; Protein Serine-Threonine Kinases; Protein Transport; Pyridines; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Up-Regulation

2002
Tumor initiating activity of Helicobacter pylori water extract on mouse skin carcinogenesis.
    Cancer letters, 2003, Feb-28, Volume: 191, Issue:1

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Alleles; Animals; Carcinogens; Cell Fractionation; Cocarcinogenesis; Codon; Deoxyguanosine; Disease Progression; DNA; DNA Adducts; DNA Damage; Female; Genes, ras; Helicobacter pylori; Luminescent Measurements; Mice; Mice, Inbred SENCAR; Oxidative Stress; Papilloma; Peroxidase; Point Mutation; Skin; Skin Neoplasms; Superoxides; Tetradecanoylphorbol Acetate; Water

2003
Free radical generating agents lead to the rapid progression of benign skin tumors to carcinoma in iron-overloaded mice.
    Archives of toxicology, 2004, Volume: 78, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzene Derivatives; Benzoyl Peroxide; Carcinogens; Carcinoma, Squamous Cell; Disease Progression; Female; Free Radicals; Hydrogen Peroxide; Iron; Iron Overload; Iron-Dextran Complex; Mice; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate

2004
Crosstalk between PARP-1 and NF-kappaB modulates the promotion of skin neoplasia.
    Oncogene, 2004, Jul-08, Volume: 23, Issue:31

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Binding Sites; Carcinogens; Cell Division; Disease Progression; Enzyme Activation; Epidermis; Epithelium; Inflammation; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Fluorescence; Mitosis; NF-kappa B; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Poly(ADP-ribose) Polymerases; Promoter Regions, Genetic; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors

2004
Mutually exclusive mutations of the Pten and ras pathways in skin tumor progression.
    Genes & development, 2004, Aug-01, Volume: 18, Issue:15

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Disease Progression; Genes, ras; Heterozygote; Homozygote; Loss of Heterozygosity; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinases; Mutation; Papilloma; Protein Tyrosine Phosphatases; PTEN Phosphohydrolase; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Suppressor Proteins

2004
Chemiluminescence: comparison of whole blood with isolated polymorphonuclear leukocytes after major trauma.
    The Journal of trauma, 2004, Volume: 57, Issue:2

    Topics: Case-Control Studies; Cell Separation; Disease Progression; Humans; Inflammation; Injury Severity Score; Luminescent Measurements; Macrophage-1 Antigen; Multiple Organ Failure; Multiple Trauma; NADP; Neutrophil Activation; Neutrophils; Patient Selection; Predictive Value of Tests; Reactive Oxygen Species; Respiratory Burst; Respiratory Distress Syndrome; Risk Factors; Statistics, Nonparametric; Tetradecanoylphorbol Acetate; Time Factors; Zymosan

2004
Inhibition of angiogenesis by growth factor receptor bound protein 2-Src homology 2 domain bound antagonists.
    Molecular cancer therapeutics, 2004, Volume: 3, Issue:10

    Topics: Adaptor Proteins, Signal Transducing; Animals; Cell Line; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cells, Cultured; Chick Embryo; Collagen; Disease Progression; Drug Combinations; Endothelium, Vascular; Extracellular Matrix; Fibroblast Growth Factor 2; GRB2 Adaptor Protein; Growth Substances; Humans; Laminin; Models, Chemical; Neovascularization, Pathologic; Protein Binding; Proteoglycans; Signal Transduction; src Homology Domains; Tetradecanoylphorbol Acetate

2004
Phorbol ester phorbol-12-myristate-13-acetate promotes anchorage-independent growth and survival of melanomas through MEK-independent activation of ERK1/2.
    Biochemical and biophysical research communications, 2005, Apr-01, Volume: 329, Issue:1

    Topics: Anoikis; Apoptosis; Butadienes; Carbazoles; Cell Adhesion; Cell Culture Techniques; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Progression; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Humans; Immunoblotting; Indoles; Melanocytes; Melanoma; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Nitriles; Oligonucleotides, Antisense; Protein Kinase C; Protein Kinase C-alpha; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors; Transfection

2005
Mitogen regulated induction of FRA-1 proto-oncogene is controlled by the transcription factors binding to both serum and TPA response elements.
    Oncogene, 2005, Jun-16, Volume: 24, Issue:26

    Topics: Activating Transcription Factors; Blood Proteins; Breast Neoplasms; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Mitogens; Promoter Regions, Genetic; Proto-Oncogene Mas; Proto-Oncogene Proteins c-fos; Serum Response Element; Tetradecanoylphorbol Acetate; Transcription Factors; Tumor Cells, Cultured

2005
PACE4 expression in mouse basal keratinocytes results in basement membrane disruption and acceleration of tumor progression.
    Cancer research, 2005, Aug-15, Volume: 65, Issue:16

    Topics: Animals; Basement Membrane; Cell Growth Processes; Disease Progression; Female; Keratinocytes; Male; Matrix Metalloproteinase 14; Matrix Metalloproteinase 15; Matrix Metalloproteinases, Membrane-Associated; Metalloendopeptidases; Mice; Mice, Transgenic; Proprotein Convertases; Serine Endopeptidases; Skin Neoplasms; Tetradecanoylphorbol Acetate

2005
The impact of altered annexin I protein levels on apoptosis and signal transduction pathways in prostate cancer cells.
    The Prostate, 2006, Sep-15, Volume: 66, Issue:13

    Topics: Annexin A1; Apoptosis; Cell Line; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Progression; Epidermal Growth Factor; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation, Neoplastic; Humans; Male; MAP Kinase Kinase 4; p38 Mitogen-Activated Protein Kinases; Prostatic Neoplasms; Signal Transduction; Tetradecanoylphorbol Acetate

2006
Homozygous K5Cre transgenic mice have wavy hair and accelerated malignant progression in a murine model of skin carcinogenesis.
    Molecular carcinogenesis, 2007, Volume: 46, Issue:1

    Topics: Alopecia; Animals; Carcinogens; Cell Transformation, Neoplastic; Cocarcinogenesis; Disease Models, Animal; Disease Progression; DNA Damage; Female; Genes, ras; Genotype; Hair; Hair Follicle; Homozygote; Integrases; Keratin-15; Keratin-5; Keratinocytes; Male; Mammary Glands, Animal; Mice; Mice, Transgenic; Papilloma; Recombination, Genetic; Skin Neoplasms; Tetradecanoylphorbol Acetate

2007
Forced expression of a constitutively active form of Stat3 in mouse epidermis enhances malignant progression of skin tumors induced by two-stage carcinogenesis.
    Oncogene, 2008, Feb-14, Volume: 27, Issue:8

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Cell Line, Tumor; Cell Transformation, Neoplastic; Disease Models, Animal; Disease Progression; Epidermis; Keratinocytes; Mice; Mice, Transgenic; Skin Neoplasms; STAT3 Transcription Factor; Tetradecanoylphorbol Acetate

2008
Cdk2 deficiency decreases ras/CDK4-dependent malignant progression, but not myc-induced tumorigenesis.
    Cancer research, 2007, Oct-15, Volume: 67, Issue:20

    Topics: Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Disease Progression; Enzyme Activation; Female; Male; Mice; Mice, Transgenic; Proto-Oncogene Proteins c-myc; ras Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate

2007
Changes in the distribution pattern of Claudin tight junction proteins during the progression of mouse skin tumorigenesis.
    BMC cancer, 2007, Oct-18, Volume: 7

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Claudin-1; Disease Progression; Epidermis; Gene Expression; Membrane Proteins; Mice; Models, Animal; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tight Junctions; Time Factors

2007
RasGRP1 overexpression in the epidermis of transgenic mice contributes to tumor progression during multistage skin carcinogenesis.
    Cancer research, 2007, Nov-01, Volume: 67, Issue:21

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Disease Progression; Epidermis; Female; Guanine Nucleotide Exchange Factors; Keratinocytes; Male; Mice; Mice, Transgenic; Skin Neoplasms; Tetradecanoylphorbol Acetate

2007
Characterisation of aromatase expression in the human adipocyte cell line SGBS.
    Breast cancer research and treatment, 2008, Volume: 112, Issue:3

    Topics: Adipocytes; Adipose Tissue; Aromatase; Cell Line; Colforsin; Cytochrome P-450 Enzyme System; Disease Progression; DNA, Complementary; Estrogens; Humans; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors

2008
Translation inhibitor Pdcd4 is targeted for degradation during tumor promotion.
    Cancer research, 2008, Mar-01, Volume: 68, Issue:5

    Topics: Animals; Apoptosis Regulatory Proteins; Cell Transformation, Neoplastic; Disease Progression; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Transgenic; Proteasome Endopeptidase Complex; Ribosomal Protein S6 Kinases, 70-kDa; RNA-Binding Proteins; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate

2008
TNF-alpha drives matrix metalloproteinase-9 in squamous oral carcinogenesis.
    The Laryngoscope, 2008, Volume: 118, Issue:8

    Topics: Cell Line, Tumor; Disease Progression; Enzyme Activation; Humans; Matrix Metalloproteinase 9; Mouth Neoplasms; Neoplasm Invasiveness; Neoplasms, Squamous Cell; Precancerous Conditions; RNA, Messenger; Saliva; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Up-Regulation

2008
Cytokine patterns during progression to AIDS in children with perinatal HIV infection.
    Journal of immunology (Baltimore, Md. : 1950), 1995, Oct-15, Volume: 155, Issue:8

    Topics: Acquired Immunodeficiency Syndrome; Cytokines; Disease Progression; Female; HIV Infections; Humans; Infant; Infant, Newborn; Ionomycin; Lymphocyte Activation; Pregnancy; Pregnancy Complications, Infectious; Prospective Studies; RNA, Messenger; Tetradecanoylphorbol Acetate; Th1 Cells; Th2 Cells

1995
Peripheral lymphocytes of clinically non-progressor patients harbor inactive and uninducible HIV proviruses.
    Journal of medical virology, 1995, Volume: 46, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Cohort Studies; Disease Progression; DNA, Viral; Follow-Up Studies; Gene Products, gag; HIV; HIV Infections; HIV Seropositivity; Humans; Lymphocytes; Macrophages; Phytohemagglutinins; Polymerase Chain Reaction; Proviruses; RNA, Viral; Tetradecanoylphorbol Acetate; Virus Activation; Virus Latency

1995
Malignant progression of papillomas induced by the initiation--promotion protocol in NMRI mouse skin.
    Carcinogenesis, 1995, Volume: 16, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma; Disease Models, Animal; Disease Progression; Female; Mice; Mice, Inbred Strains; Models, Statistical; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate

1995
Changes in superoxide anion production and phagocytosis by circulating neutrophils during tumor progression in a rat model.
    Cellular immunology, 1996, Jun-15, Volume: 170, Issue:2

    Topics: Animals; Disease Models, Animal; Disease Progression; Female; Humans; Kidney Neoplasms; Leukocyte Count; Male; Nephroma, Mesoblastic; Neutrophils; Phagocytosis; Rats; Rats, Inbred F344; Superoxides; Tetradecanoylphorbol Acetate

1996
Up-regulation of vascular endothelial growth factor/vascular permeability factor in mouse skin carcinogenesis correlates with malignant progression state and activated H-ras expression levels.
    Cancer research, 1996, Dec-01, Volume: 56, Issue:23

    Topics: Animals; Carcinoma, Squamous Cell; Cell Line, Transformed; Cell Transformation, Neoplastic; Disease Progression; Endothelial Growth Factors; Female; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Genes, ras; Interleukin 1 Receptor Antagonist Protein; Keratinocytes; Lymphokines; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred SENCAR; Neoplasm Metastasis; Neoplasm Proteins; Neovascularization, Pathologic; Oncogene Protein p21(ras); Papilloma; Precancerous Conditions; Proto-Oncogene Proteins p21(ras); RNA, Messenger; RNA, Neoplasm; Sialoglycoproteins; Skin Neoplasms; Species Specificity; Tetradecanoylphorbol Acetate; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

1996
T cell-T cell activation in multiple sclerosis.
    Multiple sclerosis (Houndmills, Basingstoke, England), 1997, Volume: 3, Issue:4

    Topics: Antigens, CD; CD3 Complex; Cells, Cultured; Disease Progression; Humans; Ionomycin; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Multiple Sclerosis; Recurrence; Reference Values; T-Lymphocytes; Tetradecanoylphorbol Acetate

1997
Topical retinoic acid reduces skin papilloma formation but resistant papillomas are at high risk for malignant conversion.
    Cancer research, 1998, Apr-01, Volume: 58, Issue:7

    Topics: Administration, Topical; Animals; Anticarcinogenic Agents; Antineoplastic Agents; Biomarkers, Tumor; Carcinogens; Carcinoma, Basal Cell; Cell Transformation, Neoplastic; Disease Progression; Diterpenes; Female; Immunohistochemistry; Mice; Mice, Inbred BALB C; Mice, Inbred SENCAR; Papilloma; Phenotype; Precancerous Conditions; Receptors, Retinoic Acid; Retinoid X Receptors; Risk Factors; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate; Transcription Factors; Transforming Growth Factor beta; Tretinoin

1998
Dissolution of type I collagen fibrils by gingival fibroblasts isolated from patients of various periodontitis categories.
    Journal of periodontal research, 1998, Volume: 33, Issue:5

    Topics: Adolescent; Adult; Age Factors; Aged; Aggressive Periodontitis; Analysis of Variance; Carcinogens; Cells, Cultured; Child; Collagen; Collagenases; Disease Progression; Disease Susceptibility; Female; Fibroblasts; Gingiva; Humans; Interleukin-1; Male; Metalloendopeptidases; Middle Aged; Periodontal Attachment Loss; Periodontitis; Regression Analysis; Tetradecanoylphorbol Acetate; Time Factors

1998
Analysis of centrosome abnormalities and angiogenesis in epidermal-targeted p53172H mutant and p53-knockout mice after chemical carcinogenesis: evidence for a gain of function.
    Molecular carcinogenesis, 1998, Volume: 23, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Centrosome; Disease Progression; Endothelial Growth Factors; Genes, p53; Humans; Lymphokines; Mice; Mice, Knockout; Neovascularization, Pathologic; Papilloma; Phenotype; Point Mutation; Skin Neoplasms; Tetradecanoylphorbol Acetate; Thrombospondin 1; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

1998
Genetic deletion of p21WAF1 enhances papilloma formation but not malignant conversion in experimental mouse skin carcinogenesis.
    Cancer research, 1999, May-01, Volume: 59, Issue:9

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Differentiation; Biomarkers; Carcinogens; Carcinoma, Squamous Cell; Cell Division; Cocarcinogenesis; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Disease Progression; Epidermis; Gene Deletion; Genes, p53; Genotype; Hyperplasia; Mice; Mice, Knockout; Mitotic Index; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53

1999
Altered expression of interleukin-1 receptor antagonist in different stages of mouse skin carcinogenesis.
    Molecular carcinogenesis, 1999, Volume: 24, Issue:4

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anthralin; Blotting, Northern; Blotting, Western; Carcinogens; Carcinoma, Squamous Cell; Cell Polarity; Cytoplasm; Disease Progression; Epidermis; Gene Expression Regulation, Neoplastic; Hyperplasia; Inflammation; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Keratinocytes; Mice; Mice, Inbred SENCAR; Neoplasm Proteins; Papilloma; Precancerous Conditions; RNA, Messenger; RNA, Neoplasm; Sialoglycoproteins; Skin Diseases; Skin Neoplasms; Tetradecanoylphorbol Acetate; Thapsigargin; Tumor Cells, Cultured

1999
Human papillomavirus types 16 E6 and E7 contribute differently to carcinogenesis.
    Virology, 2000, Feb-15, Volume: 267, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cocarcinogenesis; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Genes, ras; Humans; Mice; Mice, Transgenic; Mutation; Oncogene Proteins, Viral; Papilloma; Papillomavirus E7 Proteins; Repressor Proteins; Severity of Illness Index; Skin Neoplasms; Tetradecanoylphorbol Acetate

2000
Allelotype analysis of chemically induced squamous cell carcinomas in F(1) hybrids of two inbred mouse strains with different susceptibility to tumor progression.
    Carcinogenesis, 2000, Volume: 21, Issue:7

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Alleles; Animals; Carcinogens; Carcinoma, Squamous Cell; Chimera; Crosses, Genetic; Disease Progression; Genetic Predisposition to Disease; Genotype; Humans; Loss of Heterozygosity; Mice; Mice, Inbred SENCAR; Microsatellite Repeats; Skin Neoplasms; Tetradecanoylphorbol Acetate

2000
Tumor necrosis factor-alpha represses androgen sensitivity in the LNCaP prostate cancer cell line.
    The Journal of urology, 2000, Volume: 164, Issue:3 Pt 1

    Topics: Antibiotics, Antineoplastic; Blotting, Northern; Blotting, Western; Carcinogens; Cell Division; Dactinomycin; Dihydrotestosterone; Disease Progression; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Luciferases; Male; Promoter Regions, Genetic; Prostate-Specific Antigen; Prostatic Neoplasms; Receptors, Androgen; RNA Processing, Post-Transcriptional; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

2000
Targeted disruption of the epidermal growth factor receptor inhibits development of papillomas and carcinomas from human papillomavirus-immortalized keratinocytes.
    Cancer research, 2000, Aug-15, Volume: 60, Issue:16

    Topics: Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Line, Transformed; Cell Transformation, Viral; Cocarcinogenesis; Disease Progression; ErbB Receptors; Gene Expression; Genes, ras; Genotype; Humans; Keratinocytes; Mice; Mice, Inbred BALB C; Mice, Nude; Mutation; Oncogene Proteins, Viral; Papilloma; Papillomaviridae; Papillomavirus E7 Proteins; Repressor Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate

2000
Constitutive expression of erbB2 in epidermis of transgenic mice results in epidermal hyperproliferation and spontaneous skin tumor development.
    Oncogene, 2000, Aug-31, Volume: 19, Issue:37

    Topics: Animals; Carcinogens; Carcinoma, Squamous Cell; Cattle; Cell Differentiation; Cell Division; Cell Transformation, Neoplastic; Cocarcinogenesis; Dimerization; Disease Progression; Epidermis; ErbB Receptors; Female; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Genes, erbB-2; Genes, ras; Genes, Synthetic; Hyperplasia; Keratins; Male; Mice; Mice, Inbred ICR; Mice, Transgenic; Neoplasm Proteins; Papilloma; Phosphorylation; Promoter Regions, Genetic; Protein Processing, Post-Translational; Rats; Receptor, ErbB-2; Receptor, ErbB-3; Recombinant Fusion Proteins; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transgenes

2000
Protein kinase C-epsilon transgenic mice: a unique model for metastatic squamous cell carcinoma.
    Cancer research, 2001, Feb-01, Volume: 61, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Disease Models, Animal; Disease Progression; Female; Hair Follicle; Isoenzymes; Lymphatic Metastasis; Male; Mice; Mice, Transgenic; Protein Kinase C; Protein Kinase C-epsilon; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate

2001
Expression of microtubule-associated protein 2 in benign and malignant melanocytes: implications for differentiation and progression of cutaneous melanoma.
    The American journal of pathology, 2001, Volume: 158, Issue:6

    Topics: Acetamides; Biomarkers; Cell Differentiation; Cell Line; Cyclic AMP; Disease Progression; Gene Expression Profiling; Humans; Melanocytes; Melanoma; Microtubule-Associated Proteins; RNA, Messenger; RNA, Neoplasm; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Up-Regulation

2001
High-dose methylprednisolone prevents vasospasm after subarachnoid hemorrhage through inhibition of protein kinase C activation.
    Neurological research, 2002, Volume: 24, Issue:2

    Topics: Angiography; Animals; Anti-Inflammatory Agents; Basilar Artery; Disease Models, Animal; Disease Progression; Dogs; Dose-Response Relationship, Drug; Isometric Contraction; Methylprednisolone; Muscle, Smooth, Vascular; Potassium; Protein Kinase C; Subarachnoid Hemorrhage; Tetradecanoylphorbol Acetate; Vasoconstriction; Vasospasm, Intracranial

2002
Adrenalectomy abrogates reduction of 12-O-tetradecanoylphorbol-13-acetate-induced extracellular signal-regulated protein kinase activity in the epidermis of dietary energy-restricted SENCAR mice: implications of glucocorticoid hormone.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2002, Volume: 11, Issue:3

    Topics: Adrenalectomy; Animals; Corticosterone; Disease Progression; Energy Intake; Epidermis; Female; Mice; Mice, Inbred SENCAR; Protein Kinases; Tetradecanoylphorbol Acetate

2002
Mice deficient in the Rac activator Tiam1 are resistant to Ras-induced skin tumours.
    Nature, 2002, Jun-20, Volume: 417, Issue:6891

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Cell Division; Disease Progression; Gene Dosage; Genotype; Guanine Nucleotide Exchange Factors; Immunohistochemistry; Keratins; Mice; Mice, Knockout; Proteins; ras Proteins; Skin Neoplasms; T-Lymphoma Invasion and Metastasis-inducing Protein 1; Tetradecanoylphorbol Acetate

2002
Calgranulins S100A8 and S100A9 are negatively regulated by glucocorticoids in a c-Fos-dependent manner and overexpressed throughout skin carcinogenesis.
    Oncogene, 2002, Jun-20, Volume: 21, Issue:27

    Topics: Animals; Anti-Inflammatory Agents; Antigens, Differentiation; Antineoplastic Agents, Hormonal; Calcium; Calcium-Binding Proteins; Calgranulin A; Calgranulin B; Carcinogens; Carcinoma, Squamous Cell; Dexamethasone; Disease Progression; Drug Eruptions; Female; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Genes, fos; Keratinocytes; Leukocytes; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Knockout; Papilloma; Protein Kinase C; Proto-Oncogene Proteins c-fos; S100 Proteins; Skin Neoplasms; Specific Pathogen-Free Organisms; Tetradecanoylphorbol Acetate; Transcription Factor AP-1

2002