tetradecanoylphorbol acetate has been researched along with Disease Exacerbation in 79 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 12 (15.19) | 18.2507 |
2000's | 39 (49.37) | 29.6817 |
2010's | 27 (34.18) | 24.3611 |
2020's | 1 (1.27) | 2.80 |
Authors | Studies |
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Ding, ZD; Fu, YJ; Jiang, YJ; Shang, H; Song, CB; Xu, JJ; Zhang, ZN; Zheng, JF | 1 |
Dahlhoff, M; Fröhlich, T; Goebeler, M; Hoesl, C; Hundt, JE; Kneitz, H; Schneider, MR; Wolf, R | 1 |
Fukui, H; Kobayashi, M; Mizuguchi, H; Sato, Y; Tamaki, M; Tokashiki, N; Yamamoto, K; Yamauchi, A | 1 |
Christensen, R; Füchtbauer, AC; Füchtbauer, EM; Gunnarsson, A; Jensen, UB; Owens, DM; Ramsing, M | 1 |
Anguish, LJ; Coonrod, SA; Horibata, S; McElwee, JL; McLean, D; Mohanan, S; Mukai, C; Sams, K; Yan, A | 1 |
Chen, JK; Chu, WK; Dai, PM; Li, HL; Pao, CC | 1 |
Bougiouklis, D; Chatzizisi, O; Diza-Mataftsi, E; Gounari, E; Iakovidis, D; Kontakiotis, T; Kyriazis, G; Markopoulou, A; Papakosta, D; Serasli, E; Zoglopitis, F | 1 |
Aoto, Y; Goitsuka, R; Hachiya, T; Hirose, S; Isogai, E; Katsuragi, Y; Kominami, R; Nakamura, T; Okumura, K; Saito, M; Sakakibara, Y; Wakabayashi, Y | 1 |
Athar, M; Cochran, JB; Elmets, CA; McKay, KM; Nasti, TH; Timares, L; Tsuruta, Y; Yusuf, N | 1 |
Bao, R; Bechill, J; Bindokas, VP; Faber, PW; Lingen, MW; Spiotto, MT; Zhong, R | 1 |
Davison, G; Izzat, HJ; Jones, AW; Lewis, KE; Mohamed, P; Robinson, R | 1 |
Davidson, B; Flørenes, VA; Jørgensen, K; Rosnes, AK; Skrede, M; Slipicevic, A; Trøen, G | 1 |
Chandler, PR; Duhadaway, JB; Everhart, ME; Johnson, BA; Kahler, DJ; Mellor, AL; Muller, AJ; Munn, DH; Pihkala, J; Prendergast, GC; Sharma, MD; Soler, AP | 1 |
Fujiki, H; Suganuma, M | 1 |
Arbeit, JM; Kladney, RD; Martin, RJ; Neumann, RG; Scortegagna, M | 1 |
Chao, SC; Hu, DN; Lin, CY; Yang, PY; Yang, SF; Ye, YZ | 1 |
Arthur, JS; Burns, CJ; Efimova, T; Gribben, EL; Hindes, A; Kissling, GE; Lin, MH; Longmore, GD; Owen, RJ; Schindler, EM; Yin, Y | 1 |
Andersen, O; Bergström, T; Hellstrand, K; Mossberg, N; Movitz, C; Nilsson, S | 1 |
Gaestel, M; Iversen, L; Johansen, C; Kollias, G; Kragballe, K; Vestergaard, C | 1 |
Fischer, SM; Herschman, HR; Huang, SC; Ishikawa, TO; Kumar, IP; Kusewitt, D; Machado, HB; Wong, KP | 1 |
Chang, EI; Ikonomidis, JS; Jones, JA; Koval, C; Sheats, N; Spinale, FG; Stroud, RE; Zavadzkas, JA | 1 |
Glick, AB; Kennett, MJ; Masiuk, KE; Mordasky Markell, L; Pérez-Lorenzo, R | 1 |
Aboodi, GM; Glogauer, M; Goldberg, MB | 1 |
Akakura, S; Bouchard, R; Bshara, W; Gelman, IH; Morrison, C | 1 |
Abel, E; Fischer, SM; Mikulec, C; Pavone, A; Rundhaug, J; Surh, I | 1 |
Jin, JY; Leshin, B; Lutfeali, S; Miliani de Marval, P; Selim, MA; Zhang, JY | 1 |
Buchl, S; He, H; Nehete, B; Nehete, PN; Sastry, KJ; Wieder, E; Yang, G | 1 |
Chang, TY; Cheng, CC; Hu, CT; Lee, MC; Pan, SM; Wang, HT; Wang, LJ; Wang, S; Wu, JR; Wu, WS | 1 |
Abecasis, R; Billordo, LA; Cherñavsky, AC; Ferreyra Solari, NE; Gadano, AC; Inzaugarat, ME | 1 |
Chaiswing, L; Dhar, SK; Oberley, TD; St Clair, DK; Tangpong, J | 1 |
Bendt, KM; Edwards, RH; Moore, DT; Nielsen, JN; Raab-Traub, N; Shair, KH | 1 |
da Rocha, LF; Dantas, AT; Duarte, ÂL; Galdino, SL; Mariz, HA; Pitta, Ida R; Pitta, MG | 1 |
Guo, X; Kimura, S; Sasaguri, Y; Shimajiri, S; Tanimoto, A; Tasaki, T; Wang, KY; Yamada, S | 1 |
Chang, Y; Chen, JY; Chou, SP; Fang, CY; Hsu, HY; Huang, SY; Takada, K; Tsai, CH; Wu, CC | 1 |
Azorsa, DO; Byron, SA; Hostetter, G; Kim, S; Little, TH; Min, E; Tapia, C; Thal, TS; Watanabe, AT | 1 |
Braeuning, A; Münzel, PA; Schwarz, M | 1 |
Ho, YS; Lee, WS; Liang, YC; Lin, SY; Pan, S; Tsai, SH | 1 |
Ichiishi, E; Ishikawa, T; Kokura, S; Kuchide, M; Naito, Y; Nishino, H; Tokuda, H; Toyokuni, S; Yoshida, N; Yoshikawa, T | 1 |
Athar, M; Bhasin, G; Kauser, H | 1 |
Aguilar, M; Garcia del Moral, R; Martín-Oliva, D; Muñoz-Gámez, JA; Nuñez, MI; O'Valle, F; Oliver, FJ; Ruiz de Almodóvar, JM; Valenzuela, MT | 1 |
Balmain, A; Del Rosario, R; Mao, JH; Perez-Losada, J; To, MD; Wu, D | 1 |
Pallister, I; Topley, N | 1 |
Bottaro, DP; Burke, TR; Gao, Y; Ishibashi, T; Liu, N; Soriano, JV; Underhill, C; Yao, ZJ | 1 |
Cruciani, V; Flørenes, VA; Jørgensen, K; Mikalsen, SO; Skrede, M; Slipicevic, A | 1 |
Adiseshaiah, P; Kalvakolanu, DV; Peddakama, S; Reddy, SP; Zhang, Q | 1 |
Bassi, DE; Cenna, J; Cukierman, E; Klein-Szanto, AJ; Litwin, S; Lopez De Cicco, R | 1 |
Hsiang, CH; Ornstein, DK; Tunoda, T; Tyson, DR; Whang, YE | 1 |
Chan, EL; Collins, MH; Kader, SA; Pathrose, P; Peace, BE; Toney, K; Waltz, SE | 1 |
Abel, E; Beltran, L; Carbajal, S; Chan, KS; Clifford, J; Digiovanni, J; Kataoka, K; Peavey, M; Sano, S; Shen, J | 1 |
Kim, Y; Klein-Szanto, A; Macias, E; Miliani de Marval, PL; Rodriguez-Puebla, ML | 1 |
Arabzadeh, A; Troy, TC; Turksen, K | 1 |
Cline, JM; Lorenzo, PS; Luke, CT; Oki-Idouchi, CE | 1 |
Brown, KA; Chand, AL; Clyne, CD; Knower, KC; McInnes, KJ; Simpson, ER | 1 |
Baker, AR; Colburn, NH; Hagan, JP; Hegamyer, G; Jansen, AP; Schmid, T | 1 |
Griffin, T; Hohberger, L; Ondrey, F; Wuertz, BR; Xie, H | 1 |
Bartkowiak, J; Hyjek, E; Hyslop, T; Kozbor, D; Kubin, M; Lischner, HW; Trinchieri, G | 1 |
Benedetto, A; Delfini, C; Di Caro, A; Di Sora, F; Garbuglia, AR; Montella, F; Recchia, O; Salvi, R | 1 |
Fürstenberger, G; Kopp-Schneider, A | 1 |
Adány, R; Karányi, Z; Kávai, M; Kertai, P; Pocsai, Z; Szucs, S; Varga, C | 1 |
Cano, A; Conti, CJ; Duran, H; Jorcano, JL; Larcher, F; Murillas, R; Quintanilla, M; Robles, AI | 1 |
Honn, KV; Trikha, M | 1 |
Kerman, RH; Lindsey, JW; Wolinsky, JS | 1 |
Darwiche, N; De Luca, LM; Gartsbein, M; Hansen, L; Hennings, H; Lowry, D; Morgan, DL; Tennenbaum, T; Yuspa, SH | 1 |
Birkedal-Hansen, H; Havemose-Poulsen, A; Holmstrup, P; Stoltze, K | 1 |
Brinkley, BR; Greenhalgh, DA; He, D; Jiang, A; Roop, DR; Wang, XJ; Zhong, L | 1 |
Deng, C; Fernandez-Salas, E; Hennings, H; Mirosh, E; Morgan, DL; Shalizi, A; Stanulis, E; Weinberg, WC; Yuspa, SH | 1 |
Fischer, SM; La, E; Locniskar, MF; Muga, SJ | 1 |
Lambert, PF; Liem, A; Miller, JA; Song, S | 1 |
Benavides, F; Conti, CJ; Klingelberger, EA; Stern, MC | 1 |
Gotoh, A; Keller, ET; Matsumoto, T; Mizokami, A; Yamada, H | 1 |
Gaiotti, D; Hansen, L; Michael, E; Nees, M; Woodworth, CD | 1 |
Beltrán, L; Bol, D; Carbajal, S; Chan, K; DiGiovanni, J; Jorcano, J; Kiguchi, K; Moats, S | 1 |
Dreckschmidt, NE; Jansen, AP; Oberley, TD; Verma, AK; Verwiebe, EG; Wheeler, DL | 1 |
Fang, D; Hallman, J; Hammarback, JA; Kute, TE; Sangha, N; Setaluri, V; White, WL | 1 |
Febbraio, M; Hajjar, DP; Han, J; Nicholson, AC; Silversterin, RL | 1 |
Chen, D; Namba, H; Nishizawa, S; Ohta, S; Yokota, N; Yokoyama, T | 1 |
Birt, DF; Hawley, J; Liu, Y; Wang, W | 1 |
Clark, K; Collard, JG; Malliri, A; Michiels, F; van der Kammen, RA; van der Valk, M | 1 |
Angel, P; Breitenbach, U; Dittrich, BT; Gebhardt, C; Richter, KH; Tuckermann, JP | 1 |
4 review(s) available for tetradecanoylphorbol acetate and Disease Exacerbation
Article | Year |
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Carcinogenic aspects of protein phosphatase 1 and 2A inhibitors.
Topics: Animals; Carcinogens; Disease Progression; Enzyme Inhibitors; Humans; Marine Toxins; Mice; Models, Molecular; Neoplasms; Neoplasms, Experimental; Okadaic Acid; Oxazoles; Protein Phosphatase 1; Protein Phosphatase 2; Rats; Skin Neoplasms; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2009 |
Non-melanoma skin cancer in mouse and man.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Disease Models, Animal; Disease Progression; Genes, p53; Genes, ras; Humans; Melanoma; Mice; Mutation; Neoplasm Invasiveness; Neoplastic Stem Cells; Papilloma; Risk Assessment; Skin; Skin Neoplasms; Species Specificity; Tetradecanoylphorbol Acetate | 2013 |
Role of 12-lipoxygenase and protein kinase C in modulating the activation state of the integrin alpha IIb beta 3 on human tumor cells.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Arachidonate 12-Lipoxygenase; Cell Adhesion; Cell Movement; Disease Progression; Enzyme Activation; Extracellular Matrix; Humans; Models, Biological; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Proteins; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1997 |
Role of CD36, the macrophage class B scavenger receptor, in atherosclerosis.
Topics: Arteriosclerosis; CD36 Antigens; Disease Progression; Foam Cells; Gene Expression Regulation; Humans; Lipoproteins, LDL; Macrophages; Membrane Proteins; Receptors, Cytoplasmic and Nuclear; Receptors, Immunologic; Receptors, Lipoprotein; Receptors, Scavenger; Scavenger Receptors, Class B; Tetradecanoylphorbol Acetate; Transcription Factors; Transcription, Genetic | 2001 |
75 other study(ies) available for tetradecanoylphorbol acetate and Disease Exacerbation
Article | Year |
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Decreased CD4
Topics: Adult; Biomarkers; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Chronic Disease; Correlation of Data; Disease Progression; HIV Infections; HIV-1; Humans; Interferon-gamma; Male; Tetradecanoylphorbol Acetate; Viral Load | 2020 |
The transmembrane protein LRIG2 increases tumor progression in skin carcinogenesis.
Topics: Aged; Aged, 80 and over; Animals; Carcinogenesis; Cell Differentiation; Cell Line, Tumor; Disease Progression; Epidermis; ErbB Receptors; Homeostasis; Humans; Hyperplasia; Inflammation; Membrane Glycoproteins; Mice, Inbred C57BL; Phenotype; Protein Binding; Skin Neoplasms; Tetradecanoylphorbol Acetate; Thrombospondins | 2019 |
Protein kinase C-δ signaling regulates glucagon secretion from pancreatic islets.
Topics: Animals; Diabetes Mellitus, Experimental; Disease Progression; Glucagon; Humans; In Vitro Techniques; Islets of Langerhans; Male; Mice; Mice, Inbred C57BL; Phosphorylation; Protein Kinase C-delta; Quercetin; Signal Transduction; Tetradecanoylphorbol Acetate | 2017 |
Constitutive transgene expression of Stem Cell Antigen-1 in the hair follicle alters the sensitivity to tumor formation and progression.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Ly; Carcinogenesis; Clone Cells; Colony-Forming Units Assay; Disease Progression; Female; Hair Follicle; Integrases; Membrane Proteins; Mice, Inbred C57BL; Mice, Transgenic; Morphogenesis; Skin; Tetradecanoylphorbol Acetate; Transgenes | 2017 |
PAD2 overexpression in transgenic mice augments malignancy and tumor-associated inflammation in chemically initiated skin tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogenesis; Carcinogens; Disease Progression; Gene Expression Regulation, Neoplastic; Humans; Inflammation; Male; Mice; Mice, Transgenic; Papilloma; Protein-Arginine Deiminase Type 2; Protein-Arginine Deiminases; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Up-Regulation | 2017 |
Nanog expression is negatively regulated by protein kinase C activities in human cancer cell lines.
Topics: Carcinoma; Cell Proliferation; Disease Progression; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Gene Silencing; Hep G2 Cells; Homeodomain Proteins; Humans; Isoenzymes; Mutagenesis, Site-Directed; Nanog Homeobox Protein; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Octamer Transcription Factor-3; Promoter Regions, Genetic; Protein Kinase C-alpha; Protein Kinase C-delta; RNA, Messenger; SOXB1 Transcription Factors; Tetradecanoylphorbol Acetate; Transcription, Genetic | 2013 |
Potential prognostic value of intracellular cytokine detection by flow cytometry in pulmonary sarcoidosis.
Topics: Adult; Aged; Biomarkers; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Separation; Cytokines; Disease Progression; Flow Cytometry; Humans; Inflammation Mediators; Ionomycin; Lung; Lymphocyte Activation; Middle Aged; Prognosis; Radiography; Sarcoidosis, Pulmonary; Tetradecanoylphorbol Acetate; Th1-Th2 Balance; Young Adult | 2013 |
Meis1 regulates epidermal stem cells and is required for skin tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adult Stem Cells; Animals; Carcinogens; Carcinoma; Cell Differentiation; Cell Proliferation; Cell Transformation, Neoplastic; Disease Progression; Gene Expression Regulation, Neoplastic; Hair Follicle; Homeodomain Proteins; Keratinocytes; Mice; Mice, Transgenic; Multipotent Stem Cells; Myeloid Ecotropic Viral Integration Site 1 Protein; Neoplasm Proteins; Papilloma; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2014 |
A murine model for the development of melanocytic nevi and their progression to melanoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Line, Tumor; Cell Separation; Cyclin-Dependent Kinase Inhibitor p16; Disease Models, Animal; Disease Progression; Melanoma; Mice; Mice, Nude; Mutation; Neoplasm Proteins; Nevus, Pigmented; ras Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2016 |
Notch1 Activation or Loss Promotes HPV-Induced Oral Tumorigenesis.
Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Carcinogens; Carcinoma, Verrucous; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cocarcinogenesis; Disease Progression; DNA Transposable Elements; Female; Humans; Mice; Mice, Transgenic; Mouth Neoplasms; Mutagenesis, Insertional; Neoplasm Invasiveness; Oncogenes; Papilloma; Papillomaviridae; Receptor, Notch1; Skin Neoplasms; Specific Pathogen-Free Organisms; Tamoxifen; Tetradecanoylphorbol Acetate; Tumor Virus Infections; Uterine Cervical Neoplasms | 2015 |
Impaired Blood Neutrophil Function in the Frequent Exacerbator of Chronic Obstructive Pulmonary Disease: A Proof-of-Concept Study.
Topics: Aged; Case-Control Studies; Cell Degranulation; Disease Progression; Female; Humans; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Proof of Concept Study; Pulmonary Disease, Chronic Obstructive; Respiratory Burst; Symptom Flare Up; Tetradecanoylphorbol Acetate | 2016 |
The fatty acid binding protein 7 (FABP7) is involved in proliferation and invasion of melanoma cells.
Topics: Biomarkers, Tumor; Carcinogens; Carrier Proteins; Cell Nucleus; Cell Proliferation; Cytoplasm; Disease Progression; Enzyme Inhibitors; Fatty Acid-Binding Protein 7; Flavonoids; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Immunoblotting; Immunoenzyme Techniques; Melanoma; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neoplasm Invasiveness; Nevus, Pigmented; Oligonucleotide Array Sequence Analysis; Prognosis; RNA, Messenger; RNA, Small Interfering; Skin Neoplasms; Survival Rate; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Suppressor Proteins | 2008 |
Chronic inflammation that facilitates tumor progression creates local immune suppression by inducing indoleamine 2,3 dioxygenase.
Topics: Animals; Dendritic Cells; Dermatitis, Contact; Disease Progression; Immune Tolerance; Indoleamine-Pyrrole 2,3,-Dioxygenase; Lymph Nodes; Mice; Mice, Inbred C57BL; Models, Animal; Papilloma; Signal Transduction; Skin Neoplasms; T-Lymphocytes; Tetradecanoylphorbol Acetate | 2008 |
Hypoxia-inducible factor-1alpha suppresses squamous carcinogenic progression and epithelial-mesenchymal transition.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Cycle Proteins; Disease Progression; Epithelial Cells; Hypoxia-Inducible Factor 1, alpha Subunit; Intracellular Signaling Peptides and Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Selenium-Binding Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transfection | 2009 |
Increased expression of gelatinase (MMP-2 and MMP-9) in pterygia and pterygium fibroblasts with disease progression and activation of protein kinase C.
Topics: Cells, Cultured; Conjunctiva; Disease Progression; Enzyme Activation; Female; Fibroblasts; Gene Expression Regulation, Enzymologic; Humans; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Middle Aged; Protein Kinase C; Pterygium; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetradecanoylphorbol Acetate | 2009 |
p38delta Mitogen-activated protein kinase is essential for skin tumor development in mice.
Topics: Animals; Animals, Newborn; Carcinoma; Cell Proliferation; Disease Progression; Epidermis; Female; Genes, ras; Genotype; Hyperplasia; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinase 13; Mutation; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2009 |
Oxygen radical production in leukocytes and disease severity in multiple sclerosis.
Topics: Autoimmunity; Cytoprotection; Disease Progression; Female; Humans; Inflammation Mediators; Leukocytes; Male; Middle Aged; Multiple Sclerosis; NADPH Oxidases; Oligopeptides; Oxidative Stress; Phagocytes; Reactive Oxygen Species; Respiratory Burst; Severity of Illness Index; Superoxides; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2009 |
MK2 regulates the early stages of skin tumor promotion.
Topics: Animals; Apoptosis; Disease Progression; DNA Damage; Gene Expression Regulation, Neoplastic; Inflammation; Intracellular Signaling Peptides and Proteins; Keratinocytes; Mice; Mice, Transgenic; Phosphorylation; Protein Serine-Threonine Kinases; RNA, Small Interfering; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Tumor Suppressor Protein p53 | 2009 |
Positron emission tomography imaging of DMBA/TPA mouse skin multi-step tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Disease Progression; Female; Fluorodeoxyglucose F18; Glucose; Mice; Papilloma; Positron-Emission Tomography; Predictive Value of Tests; Radiopharmaceuticals; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tomography, X-Ray Computed | 2010 |
Cellular phenotype transformation occurs during thoracic aortic aneurysm development.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Aortic Aneurysm, Thoracic; Calcium Chloride; Cells, Cultured; Disease Models, Animal; Disease Progression; Endothelin-1; Extracellular Matrix Proteins; Female; Fibroblasts; Gene Expression Profiling; Gene Expression Regulation; Genotype; Male; Mice; Mice, Inbred C57BL; Phenotype; Reverse Transcriptase Polymerase Chain Reaction; Tetradecanoylphorbol Acetate | 2010 |
Use of a TGFbeta type I receptor inhibitor in mouse skin carcinogenesis reveals a dual role for TGFbeta signaling in tumor promotion and progression.
Topics: Animals; Benzamides; Dioxoles; Disease Progression; Genes, ras; Mice; Papilloma; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Signal Transduction; Skin Neoplasms; Smad2 Protein; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta1 | 2010 |
Refractory periodontitis population characterized by a hyperactive oral neutrophil phenotype.
Topics: Adult; Aged; Dental Plaque Index; Disease Progression; Female; Flow Cytometry; Fluorescent Dyes; Follow-Up Studies; Furcation Defects; Gingival Hemorrhage; Gingival Recession; Humans; Leukocyte Count; Male; Middle Aged; Mouth Mucosa; Neutrophil Activation; Neutrophils; Periodontal Attachment Loss; Periodontal Pocket; Periodontitis; Phenotype; Reactive Oxygen Species; Rhodamines; Tetradecanoylphorbol Acetate; Tooth Mobility | 2011 |
Carcinogen-induced squamous papillomas and oncogenic progression in the absence of the SSeCKS/AKAP12 metastasis suppressor correlate with FAK upregulation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; A Kinase Anchor Proteins; Animals; Cell Cycle Proteins; Disease Progression; Focal Adhesion Kinase 1; Gene Expression Regulation, Neoplastic; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Up-Regulation | 2011 |
Upregulation of the EP1 receptor for prostaglandin E2 promotes skin tumor progression.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Blotting, Western; Carcinogens; Cell Proliferation; Cyclooxygenase 2; Dinoprostone; Disease Progression; Epidermis; Female; Humans; Mice; Mice, Hairless; Mice, Transgenic; Receptors, Prostaglandin E, EP1 Subtype; Skin Neoplasms; Tetradecanoylphorbol Acetate; Ultraviolet Rays; Up-Regulation | 2011 |
CYLD inhibits tumorigenesis and metastasis by blocking JNK/AP1 signaling at multiple levels.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Cysteine Endopeptidases; Deubiquitinating Enzyme CYLD; Disease Progression; Epidermal Cells; Epidermis; Humans; Hyperplasia; Immunoblotting; Immunoprecipitation; JNK Mitogen-Activated Protein Kinases; Lymphatic Metastasis; Mice; Mice, Transgenic; Mutation; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Tumor Cells, Cultured; Tumor Suppressor Proteins; Ubiquitination | 2011 |
Functional impairment of central memory CD4 T cells is a potential early prognostic marker for changing viral load in SHIV-infected rhesus macaques.
Topics: Animals; Biomarkers; CD4-Positive T-Lymphocytes; Chronic Disease; Cytokines; Disease Progression; Humans; Immunologic Memory; Ionomycin; Macaca mulatta; Prognosis; Simian Acquired Immunodeficiency Syndrome; Tetradecanoylphorbol Acetate; Viral Load; Viremia | 2011 |
Reactive oxygen species-mediated PKC and integrin signaling promotes tumor progression of human hepatoma HepG2.
Topics: Animals; Blotting, Western; Carcinoma, Hepatocellular; Cell Movement; Disease Progression; Extracellular Signal-Regulated MAP Kinases; Fluorescent Antibody Technique; Humans; Integrins; Liver Neoplasms; Male; Mice; Mice, Inbred NOD; Mice, SCID; Protein Kinase C-alpha; Reactive Oxygen Species; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2011 |
Altered phenotype and functionality of circulating immune cells characterize adult patients with nonalcoholic steatohepatitis.
Topics: Adult; Aged; CD4 Antigens; CD8 Antigens; Cells, Cultured; Disease Progression; Fatty Liver; Female; Fibrosis; Gene Expression Regulation; Humans; Immunophenotyping; Interferon-gamma; Leukocyte Common Antigens; Liver; Male; Middle Aged; Monocytes; Neutrophils; Oxidative Stress; Reactive Oxygen Species; T-Lymphocytes; Tetradecanoylphorbol Acetate; Th1-Th2 Balance | 2011 |
Manganese superoxide dismutase is a p53-regulated gene that switches cancers between early and advanced stages.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Cocarcinogenesis; Disease Progression; Enhancer Elements, Genetic; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Genes, Reporter; Genes, Synthetic; Humans; Mice; Mice, Transgenic; Neoplasm Proteins; Papilloma; Promoter Regions, Genetic; Recombinant Fusion Proteins; Skin Neoplasms; Sp1 Transcription Factor; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Suppressor Protein p53 | 2011 |
Epstein-Barr virus-encoded latent membrane protein 1 (LMP1) and LMP2A function cooperatively to promote carcinoma development in a mouse carcinogenesis model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma; Cell Transformation, Viral; Disease Models, Animal; Disease Progression; Gene Expression; Genes, ras; Keratin-14; Mice; Mice, Inbred BALB C; Mice, Transgenic; Mutation; Papilloma; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Viral Matrix Proteins | 2012 |
Increased serum interleukin 22 in patients with rheumatoid arthritis and correlation with disease activity.
Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Calcium Ionophores; Carcinogens; Cells, Cultured; Disease Progression; Female; Humans; Interleukin-22; Interleukins; Ionomycin; Leukocytes, Mononuclear; Male; Middle Aged; Osteolysis; Rheumatoid Factor; Severity of Illness Index; Tetradecanoylphorbol Acetate | 2012 |
Expression of macrophage-derived chemokine (CCL22) in atherosclerosis and regulation by histamine via the H2 receptor.
Topics: Aorta; Atherosclerosis; Cell Line, Tumor; Cell Movement; Chemokine CCL22; Chemokines; Dendritic Cells; Disease Progression; Gene Expression Regulation; Histamine; Humans; Leukocytes, Mononuclear; Macrophages; Models, Molecular; Monocytes; Myocardial Ischemia; Promoter Regions, Genetic; Receptors, Histamine H2; Tetradecanoylphorbol Acetate | 2012 |
The synergistic effect of chemical carcinogens enhances Epstein-Barr virus reactivation and tumor progression of nasopharyngeal carcinoma cells.
Topics: Animals; Butyrates; Carcinogens; Carcinoma; Cell Line, Tumor; Cell Transformation, Viral; Disease Progression; Drug Synergism; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genome, Human; Genomic Instability; Herpesvirus 4, Human; Humans; Methylnitronitrosoguanidine; Mice; Mice, SCID; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplasm Invasiveness; Tetradecanoylphorbol Acetate; Virus Activation | 2012 |
Negative regulation of NF-κB by the ING4 tumor suppressor in breast cancer.
Topics: Antibodies, Monoclonal; Breast Neoplasms; Cell Cycle Proteins; Cell Line, Tumor; Disease Progression; Disease-Free Survival; Down-Regulation; Homeodomain Proteins; Humans; Neoplasm Invasiveness; Phosphorylation; Tetradecanoylphorbol Acetate; Transcription Factor RelA; Transcription, Genetic; Tumor Suppressor Proteins | 2012 |
Involvement of both extracellular signal-regulated kinase and c-jun N-terminal kinase pathways in the 12-O-tetradecanoylphorbol-13-acetate-induced upregulation of p21(Cip1) in colon cancer cells.
Topics: Adenocarcinoma; CDC2-CDC28 Kinases; Cell Cycle; Cell Division; Chromosome Mapping; Colonic Neoplasms; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinases; Cyclins; Disease Progression; Enzyme Inhibitors; Flavonoids; Humans; Imidazoles; Isoenzymes; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases; Protein Kinase C; Protein Serine-Threonine Kinases; Protein Transport; Pyridines; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Up-Regulation | 2002 |
Tumor initiating activity of Helicobacter pylori water extract on mouse skin carcinogenesis.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Alleles; Animals; Carcinogens; Cell Fractionation; Cocarcinogenesis; Codon; Deoxyguanosine; Disease Progression; DNA; DNA Adducts; DNA Damage; Female; Genes, ras; Helicobacter pylori; Luminescent Measurements; Mice; Mice, Inbred SENCAR; Oxidative Stress; Papilloma; Peroxidase; Point Mutation; Skin; Skin Neoplasms; Superoxides; Tetradecanoylphorbol Acetate; Water | 2003 |
Free radical generating agents lead to the rapid progression of benign skin tumors to carcinoma in iron-overloaded mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzene Derivatives; Benzoyl Peroxide; Carcinogens; Carcinoma, Squamous Cell; Disease Progression; Female; Free Radicals; Hydrogen Peroxide; Iron; Iron Overload; Iron-Dextran Complex; Mice; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2004 |
Crosstalk between PARP-1 and NF-kappaB modulates the promotion of skin neoplasia.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Binding Sites; Carcinogens; Cell Division; Disease Progression; Enzyme Activation; Epidermis; Epithelium; Inflammation; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Fluorescence; Mitosis; NF-kappa B; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Poly(ADP-ribose) Polymerases; Promoter Regions, Genetic; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 2004 |
Mutually exclusive mutations of the Pten and ras pathways in skin tumor progression.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Disease Progression; Genes, ras; Heterozygote; Homozygote; Loss of Heterozygosity; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinases; Mutation; Papilloma; Protein Tyrosine Phosphatases; PTEN Phosphohydrolase; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Suppressor Proteins | 2004 |
Chemiluminescence: comparison of whole blood with isolated polymorphonuclear leukocytes after major trauma.
Topics: Case-Control Studies; Cell Separation; Disease Progression; Humans; Inflammation; Injury Severity Score; Luminescent Measurements; Macrophage-1 Antigen; Multiple Organ Failure; Multiple Trauma; NADP; Neutrophil Activation; Neutrophils; Patient Selection; Predictive Value of Tests; Reactive Oxygen Species; Respiratory Burst; Respiratory Distress Syndrome; Risk Factors; Statistics, Nonparametric; Tetradecanoylphorbol Acetate; Time Factors; Zymosan | 2004 |
Inhibition of angiogenesis by growth factor receptor bound protein 2-Src homology 2 domain bound antagonists.
Topics: Adaptor Proteins, Signal Transducing; Animals; Cell Line; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cells, Cultured; Chick Embryo; Collagen; Disease Progression; Drug Combinations; Endothelium, Vascular; Extracellular Matrix; Fibroblast Growth Factor 2; GRB2 Adaptor Protein; Growth Substances; Humans; Laminin; Models, Chemical; Neovascularization, Pathologic; Protein Binding; Proteoglycans; Signal Transduction; src Homology Domains; Tetradecanoylphorbol Acetate | 2004 |
Phorbol ester phorbol-12-myristate-13-acetate promotes anchorage-independent growth and survival of melanomas through MEK-independent activation of ERK1/2.
Topics: Anoikis; Apoptosis; Butadienes; Carbazoles; Cell Adhesion; Cell Culture Techniques; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Progression; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Humans; Immunoblotting; Indoles; Melanocytes; Melanoma; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Nitriles; Oligonucleotides, Antisense; Protein Kinase C; Protein Kinase C-alpha; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors; Transfection | 2005 |
Mitogen regulated induction of FRA-1 proto-oncogene is controlled by the transcription factors binding to both serum and TPA response elements.
Topics: Activating Transcription Factors; Blood Proteins; Breast Neoplasms; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Mitogens; Promoter Regions, Genetic; Proto-Oncogene Mas; Proto-Oncogene Proteins c-fos; Serum Response Element; Tetradecanoylphorbol Acetate; Transcription Factors; Tumor Cells, Cultured | 2005 |
PACE4 expression in mouse basal keratinocytes results in basement membrane disruption and acceleration of tumor progression.
Topics: Animals; Basement Membrane; Cell Growth Processes; Disease Progression; Female; Keratinocytes; Male; Matrix Metalloproteinase 14; Matrix Metalloproteinase 15; Matrix Metalloproteinases, Membrane-Associated; Metalloendopeptidases; Mice; Mice, Transgenic; Proprotein Convertases; Serine Endopeptidases; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2005 |
The impact of altered annexin I protein levels on apoptosis and signal transduction pathways in prostate cancer cells.
Topics: Annexin A1; Apoptosis; Cell Line; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Progression; Epidermal Growth Factor; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation, Neoplastic; Humans; Male; MAP Kinase Kinase 4; p38 Mitogen-Activated Protein Kinases; Prostatic Neoplasms; Signal Transduction; Tetradecanoylphorbol Acetate | 2006 |
Homozygous K5Cre transgenic mice have wavy hair and accelerated malignant progression in a murine model of skin carcinogenesis.
Topics: Alopecia; Animals; Carcinogens; Cell Transformation, Neoplastic; Cocarcinogenesis; Disease Models, Animal; Disease Progression; DNA Damage; Female; Genes, ras; Genotype; Hair; Hair Follicle; Homozygote; Integrases; Keratin-15; Keratin-5; Keratinocytes; Male; Mammary Glands, Animal; Mice; Mice, Transgenic; Papilloma; Recombination, Genetic; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2007 |
Forced expression of a constitutively active form of Stat3 in mouse epidermis enhances malignant progression of skin tumors induced by two-stage carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Cell Line, Tumor; Cell Transformation, Neoplastic; Disease Models, Animal; Disease Progression; Epidermis; Keratinocytes; Mice; Mice, Transgenic; Skin Neoplasms; STAT3 Transcription Factor; Tetradecanoylphorbol Acetate | 2008 |
Cdk2 deficiency decreases ras/CDK4-dependent malignant progression, but not myc-induced tumorigenesis.
Topics: Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Disease Progression; Enzyme Activation; Female; Male; Mice; Mice, Transgenic; Proto-Oncogene Proteins c-myc; ras Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2007 |
Changes in the distribution pattern of Claudin tight junction proteins during the progression of mouse skin tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Claudin-1; Disease Progression; Epidermis; Gene Expression; Membrane Proteins; Mice; Models, Animal; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tight Junctions; Time Factors | 2007 |
RasGRP1 overexpression in the epidermis of transgenic mice contributes to tumor progression during multistage skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Disease Progression; Epidermis; Female; Guanine Nucleotide Exchange Factors; Keratinocytes; Male; Mice; Mice, Transgenic; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2007 |
Characterisation of aromatase expression in the human adipocyte cell line SGBS.
Topics: Adipocytes; Adipose Tissue; Aromatase; Cell Line; Colforsin; Cytochrome P-450 Enzyme System; Disease Progression; DNA, Complementary; Estrogens; Humans; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors | 2008 |
Translation inhibitor Pdcd4 is targeted for degradation during tumor promotion.
Topics: Animals; Apoptosis Regulatory Proteins; Cell Transformation, Neoplastic; Disease Progression; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Transgenic; Proteasome Endopeptidase Complex; Ribosomal Protein S6 Kinases, 70-kDa; RNA-Binding Proteins; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2008 |
TNF-alpha drives matrix metalloproteinase-9 in squamous oral carcinogenesis.
Topics: Cell Line, Tumor; Disease Progression; Enzyme Activation; Humans; Matrix Metalloproteinase 9; Mouth Neoplasms; Neoplasm Invasiveness; Neoplasms, Squamous Cell; Precancerous Conditions; RNA, Messenger; Saliva; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Up-Regulation | 2008 |
Cytokine patterns during progression to AIDS in children with perinatal HIV infection.
Topics: Acquired Immunodeficiency Syndrome; Cytokines; Disease Progression; Female; HIV Infections; Humans; Infant; Infant, Newborn; Ionomycin; Lymphocyte Activation; Pregnancy; Pregnancy Complications, Infectious; Prospective Studies; RNA, Messenger; Tetradecanoylphorbol Acetate; Th1 Cells; Th2 Cells | 1995 |
Peripheral lymphocytes of clinically non-progressor patients harbor inactive and uninducible HIV proviruses.
Topics: Acquired Immunodeficiency Syndrome; Cohort Studies; Disease Progression; DNA, Viral; Follow-Up Studies; Gene Products, gag; HIV; HIV Infections; HIV Seropositivity; Humans; Lymphocytes; Macrophages; Phytohemagglutinins; Polymerase Chain Reaction; Proviruses; RNA, Viral; Tetradecanoylphorbol Acetate; Virus Activation; Virus Latency | 1995 |
Malignant progression of papillomas induced by the initiation--promotion protocol in NMRI mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma; Disease Models, Animal; Disease Progression; Female; Mice; Mice, Inbred Strains; Models, Statistical; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1995 |
Changes in superoxide anion production and phagocytosis by circulating neutrophils during tumor progression in a rat model.
Topics: Animals; Disease Models, Animal; Disease Progression; Female; Humans; Kidney Neoplasms; Leukocyte Count; Male; Nephroma, Mesoblastic; Neutrophils; Phagocytosis; Rats; Rats, Inbred F344; Superoxides; Tetradecanoylphorbol Acetate | 1996 |
Up-regulation of vascular endothelial growth factor/vascular permeability factor in mouse skin carcinogenesis correlates with malignant progression state and activated H-ras expression levels.
Topics: Animals; Carcinoma, Squamous Cell; Cell Line, Transformed; Cell Transformation, Neoplastic; Disease Progression; Endothelial Growth Factors; Female; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Genes, ras; Interleukin 1 Receptor Antagonist Protein; Keratinocytes; Lymphokines; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred SENCAR; Neoplasm Metastasis; Neoplasm Proteins; Neovascularization, Pathologic; Oncogene Protein p21(ras); Papilloma; Precancerous Conditions; Proto-Oncogene Proteins p21(ras); RNA, Messenger; RNA, Neoplasm; Sialoglycoproteins; Skin Neoplasms; Species Specificity; Tetradecanoylphorbol Acetate; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1996 |
T cell-T cell activation in multiple sclerosis.
Topics: Antigens, CD; CD3 Complex; Cells, Cultured; Disease Progression; Humans; Ionomycin; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Multiple Sclerosis; Recurrence; Reference Values; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1997 |
Topical retinoic acid reduces skin papilloma formation but resistant papillomas are at high risk for malignant conversion.
Topics: Administration, Topical; Animals; Anticarcinogenic Agents; Antineoplastic Agents; Biomarkers, Tumor; Carcinogens; Carcinoma, Basal Cell; Cell Transformation, Neoplastic; Disease Progression; Diterpenes; Female; Immunohistochemistry; Mice; Mice, Inbred BALB C; Mice, Inbred SENCAR; Papilloma; Phenotype; Precancerous Conditions; Receptors, Retinoic Acid; Retinoid X Receptors; Risk Factors; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate; Transcription Factors; Transforming Growth Factor beta; Tretinoin | 1998 |
Dissolution of type I collagen fibrils by gingival fibroblasts isolated from patients of various periodontitis categories.
Topics: Adolescent; Adult; Age Factors; Aged; Aggressive Periodontitis; Analysis of Variance; Carcinogens; Cells, Cultured; Child; Collagen; Collagenases; Disease Progression; Disease Susceptibility; Female; Fibroblasts; Gingiva; Humans; Interleukin-1; Male; Metalloendopeptidases; Middle Aged; Periodontal Attachment Loss; Periodontitis; Regression Analysis; Tetradecanoylphorbol Acetate; Time Factors | 1998 |
Analysis of centrosome abnormalities and angiogenesis in epidermal-targeted p53172H mutant and p53-knockout mice after chemical carcinogenesis: evidence for a gain of function.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Centrosome; Disease Progression; Endothelial Growth Factors; Genes, p53; Humans; Lymphokines; Mice; Mice, Knockout; Neovascularization, Pathologic; Papilloma; Phenotype; Point Mutation; Skin Neoplasms; Tetradecanoylphorbol Acetate; Thrombospondin 1; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1998 |
Genetic deletion of p21WAF1 enhances papilloma formation but not malignant conversion in experimental mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Differentiation; Biomarkers; Carcinogens; Carcinoma, Squamous Cell; Cell Division; Cocarcinogenesis; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Disease Progression; Epidermis; Gene Deletion; Genes, p53; Genotype; Hyperplasia; Mice; Mice, Knockout; Mitotic Index; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53 | 1999 |
Altered expression of interleukin-1 receptor antagonist in different stages of mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anthralin; Blotting, Northern; Blotting, Western; Carcinogens; Carcinoma, Squamous Cell; Cell Polarity; Cytoplasm; Disease Progression; Epidermis; Gene Expression Regulation, Neoplastic; Hyperplasia; Inflammation; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Keratinocytes; Mice; Mice, Inbred SENCAR; Neoplasm Proteins; Papilloma; Precancerous Conditions; RNA, Messenger; RNA, Neoplasm; Sialoglycoproteins; Skin Diseases; Skin Neoplasms; Tetradecanoylphorbol Acetate; Thapsigargin; Tumor Cells, Cultured | 1999 |
Human papillomavirus types 16 E6 and E7 contribute differently to carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cocarcinogenesis; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Genes, ras; Humans; Mice; Mice, Transgenic; Mutation; Oncogene Proteins, Viral; Papilloma; Papillomavirus E7 Proteins; Repressor Proteins; Severity of Illness Index; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2000 |
Allelotype analysis of chemically induced squamous cell carcinomas in F(1) hybrids of two inbred mouse strains with different susceptibility to tumor progression.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alleles; Animals; Carcinogens; Carcinoma, Squamous Cell; Chimera; Crosses, Genetic; Disease Progression; Genetic Predisposition to Disease; Genotype; Humans; Loss of Heterozygosity; Mice; Mice, Inbred SENCAR; Microsatellite Repeats; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2000 |
Tumor necrosis factor-alpha represses androgen sensitivity in the LNCaP prostate cancer cell line.
Topics: Antibiotics, Antineoplastic; Blotting, Northern; Blotting, Western; Carcinogens; Cell Division; Dactinomycin; Dihydrotestosterone; Disease Progression; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Luciferases; Male; Promoter Regions, Genetic; Prostate-Specific Antigen; Prostatic Neoplasms; Receptors, Androgen; RNA Processing, Post-Transcriptional; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2000 |
Targeted disruption of the epidermal growth factor receptor inhibits development of papillomas and carcinomas from human papillomavirus-immortalized keratinocytes.
Topics: Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Line, Transformed; Cell Transformation, Viral; Cocarcinogenesis; Disease Progression; ErbB Receptors; Gene Expression; Genes, ras; Genotype; Humans; Keratinocytes; Mice; Mice, Inbred BALB C; Mice, Nude; Mutation; Oncogene Proteins, Viral; Papilloma; Papillomaviridae; Papillomavirus E7 Proteins; Repressor Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2000 |
Constitutive expression of erbB2 in epidermis of transgenic mice results in epidermal hyperproliferation and spontaneous skin tumor development.
Topics: Animals; Carcinogens; Carcinoma, Squamous Cell; Cattle; Cell Differentiation; Cell Division; Cell Transformation, Neoplastic; Cocarcinogenesis; Dimerization; Disease Progression; Epidermis; ErbB Receptors; Female; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Genes, erbB-2; Genes, ras; Genes, Synthetic; Hyperplasia; Keratins; Male; Mice; Mice, Inbred ICR; Mice, Transgenic; Neoplasm Proteins; Papilloma; Phosphorylation; Promoter Regions, Genetic; Protein Processing, Post-Translational; Rats; Receptor, ErbB-2; Receptor, ErbB-3; Recombinant Fusion Proteins; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transgenes | 2000 |
Protein kinase C-epsilon transgenic mice: a unique model for metastatic squamous cell carcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Disease Models, Animal; Disease Progression; Female; Hair Follicle; Isoenzymes; Lymphatic Metastasis; Male; Mice; Mice, Transgenic; Protein Kinase C; Protein Kinase C-epsilon; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2001 |
Expression of microtubule-associated protein 2 in benign and malignant melanocytes: implications for differentiation and progression of cutaneous melanoma.
Topics: Acetamides; Biomarkers; Cell Differentiation; Cell Line; Cyclic AMP; Disease Progression; Gene Expression Profiling; Humans; Melanocytes; Melanoma; Microtubule-Associated Proteins; RNA, Messenger; RNA, Neoplasm; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Up-Regulation | 2001 |
High-dose methylprednisolone prevents vasospasm after subarachnoid hemorrhage through inhibition of protein kinase C activation.
Topics: Angiography; Animals; Anti-Inflammatory Agents; Basilar Artery; Disease Models, Animal; Disease Progression; Dogs; Dose-Response Relationship, Drug; Isometric Contraction; Methylprednisolone; Muscle, Smooth, Vascular; Potassium; Protein Kinase C; Subarachnoid Hemorrhage; Tetradecanoylphorbol Acetate; Vasoconstriction; Vasospasm, Intracranial | 2002 |
Adrenalectomy abrogates reduction of 12-O-tetradecanoylphorbol-13-acetate-induced extracellular signal-regulated protein kinase activity in the epidermis of dietary energy-restricted SENCAR mice: implications of glucocorticoid hormone.
Topics: Adrenalectomy; Animals; Corticosterone; Disease Progression; Energy Intake; Epidermis; Female; Mice; Mice, Inbred SENCAR; Protein Kinases; Tetradecanoylphorbol Acetate | 2002 |
Mice deficient in the Rac activator Tiam1 are resistant to Ras-induced skin tumours.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Cell Division; Disease Progression; Gene Dosage; Genotype; Guanine Nucleotide Exchange Factors; Immunohistochemistry; Keratins; Mice; Mice, Knockout; Proteins; ras Proteins; Skin Neoplasms; T-Lymphoma Invasion and Metastasis-inducing Protein 1; Tetradecanoylphorbol Acetate | 2002 |
Calgranulins S100A8 and S100A9 are negatively regulated by glucocorticoids in a c-Fos-dependent manner and overexpressed throughout skin carcinogenesis.
Topics: Animals; Anti-Inflammatory Agents; Antigens, Differentiation; Antineoplastic Agents, Hormonal; Calcium; Calcium-Binding Proteins; Calgranulin A; Calgranulin B; Carcinogens; Carcinoma, Squamous Cell; Dexamethasone; Disease Progression; Drug Eruptions; Female; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Genes, fos; Keratinocytes; Leukocytes; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Knockout; Papilloma; Protein Kinase C; Proto-Oncogene Proteins c-fos; S100 Proteins; Skin Neoplasms; Specific Pathogen-Free Organisms; Tetradecanoylphorbol Acetate; Transcription Factor AP-1 | 2002 |