tetradecanoylphorbol acetate has been researched along with Di Guglielmo Disease in 173 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 55 (31.79) | 18.7374 |
| 1990's | 95 (54.91) | 18.2507 |
| 2000's | 15 (8.67) | 29.6817 |
| 2010's | 7 (4.05) | 24.3611 |
| 2020's | 1 (0.58) | 2.80 |
| Authors | Studies |
|---|---|
| Bian, LH; Gao, HW; Gong, F; Gong, L; Ji, SP; Li, JP; Li, SB; Li, W; Luo, Q; Tan, YX; Wan, LM; Wei, CW; Yun, ZM; Zhang, SK; Zhang, X; Zhong, H; Zhuo, HL | 1 |
| Chen, WM; Chiang, CL; Ho, YH; Hou, FH; Lee, H; Li, MW; Lin, CC; Lin, KH; Lin, SH; Lin, YN; Lu, J; Tigyi, G; Yang, YJ; Yao, CL | 1 |
| Kamal, MA; Patruno, A; Pesce, M; Reale, M; Shakil, S; Tabrez, S | 1 |
| Bozzi, A; Carnicelli, V; Di Giulio, A; Franceschini, N; Gualtieri, G; Lizzi, AR | 1 |
| Ishigaki, M; Kitajima, S; Masaki, R; Ohgari, Y; Sakaino, M; Taketani, S; Yamamoto, A | 1 |
| Jalagadugula, G; Kaur, G; Mao, G; Rao, AK | 1 |
| Ge, Q; Lu, Z; Shi, X; Sun, X; Tang, C; Tu, J; Wang, W; Xiao, PF; Xie, X; Zhou, D | 1 |
| Lai, HK; Lau, AH; Leung, SL; Tsang, SY; Wise, H; Wong, YH; Yeung, BH | 1 |
| Keating, GL; Kinsella, BT; Turner, EC | 1 |
| Chang, CS; McFadden, G | 1 |
| Andreu, E; Calasanz, MJ; Fernandez-Luna, JL; Prosper, F; Richard, C; Sanz, C | 1 |
| Bahou, WF; Cupit, LD; Gnatenko, DV; Schmidt, VA | 1 |
| Battu, S; Beneytout, JL; Cardot, PJ; Léger, DY; Liagre, B | 1 |
| Feng, D; Gao, T; Ling, B; Shen, G; Shi, Y; Tian, Z; Wei, H; Zhou, Y | 1 |
| Gourdin, MF; Pelicci, PG; Rochant, H; Tabilio, A; Testa, U; Thomopoulos, P; Titeux, M; Vainchenker, W | 1 |
| Friend, C; Gazitt, Y | 1 |
| Colletta, G; Di Fiore, PP; Ferrentino, M; Pietropaolo, C; Turco, MC; Vecchio, G | 1 |
| Harrison, CJ; Kimber, I; Moore, M | 1 |
| Chait, A; Kannagi, R; Nakamoto, B; Papayannopoulou, T; Yokochi, T | 1 |
| Abrams, SI; Brahmi, Z | 1 |
| Scher, W; Waxman, S | 1 |
| Marks, PA; Rifkind, RA; Sheffery, M | 1 |
| Beckman, BS; George, WJ; Pincus, SM | 1 |
| Horton, MA; Turberville, C | 1 |
| Enomoto, T; Martel, N; Yamasaki, H | 1 |
| Banks, J; Chen, ZX; Epner, E; Gambari, R; Marks, PA; Rifkind, RA | 1 |
| Bernstein, A; Mager, D | 1 |
| Zucker, RM | 1 |
| Becker, JH; Cook, JS | 1 |
| Drevon, C; Martel, N; Yamasaki, H | 2 |
| Chiarugi, V; Cinelli, M; Magnelli, L | 1 |
| Banfic, HH; Divecha, N; Irvine, RF; Letcher, AJ; Rhee, SG | 1 |
| Asano, S; Bakić, M; Ikebuchi, K; Nishikawa, M; Ozawa, K; Takahashi, K; Tani, K; Tojo, A; Uemura, N; Zaike, Y | 1 |
| Schick, BP; Thornton, RD | 1 |
| Agosti, V; Cimino, F; Cuomo, C; Esposito, F; Morra, F; Morrone, G; Russo, T; Venuta, S | 1 |
| Cohen, IR; Eichstetter, I; Grässel, S; Iozzo, RV; Murdoch, AD | 1 |
| Jacoby, JA; Schick, BP | 1 |
| Burns, DJ; Fields, AP; Murray, NR; Walker, SD | 1 |
| Burstein, SA; Caporale, R; Mocali, A; Paoletti, F; Vannucchi, AM | 1 |
| Holguin, MH; Martin, CB; Parker, CJ; Weis, JH | 1 |
| Minowada, G; Welch, W | 1 |
| Austin, ED; Austin, GE; Findley, HW; Murtagh, JJ; Zhang, W; Zhao, WG | 1 |
| Falk, LA; Halder, S; Mufson, RA; Rinaudo, MS; Su, K | 1 |
| O'Brien, TG; Rosson, D | 1 |
| Schonhorn, JE; Wessling-Resnick, M | 1 |
| Beneytout, JL; Leboutet, MJ; Malinvaud, G; Nappez, C | 1 |
| Jacoby, JA; Schick, BP; Tang, RP | 1 |
| Ramachandran, B; Schwartz, E; Surrey, S | 1 |
| Nachmias, VT; Niu, MY | 1 |
| Melloni, E; Passalacqua, M; Patrone, M; Pessino, A; Pontremoli, S; Sparatore, B | 1 |
| Delwel, GO; Hogervorst, F; Kuikman, I; Paulsson, M; Sonnenberg, A; Timpl, R | 1 |
| Kosunago, S; Matsumoto, T; Mikami, T; Sasaki, D; Suzuki, M | 1 |
| Aoki, S; Furukawa, T; Gotoh, T; Hanano, M; Hashimoto, S; Kishi, K; Koike, T; Saitoh, H; Shinada, S; Ying, W | 1 |
| Hagmann, W; Honn, KV; Kagawa, D; Renaud, C | 1 |
| Järvinen, M; Virtanen, I; Ylänne, J | 1 |
| Baumgardner, GP; Burns, DJ; Fields, AP; Murray, NR | 1 |
| Hogervorst, F; Kuikman, I; Noteboom, E; Sonnenberg, A | 1 |
| Crespo, P; Cuadrado, MA; Delgado, MD; Gómez-Casares, MT; León, J; Richard, C | 1 |
| Atweh, GF; Luo, XN; Ren, S | 1 |
| Edwards, SW; Martin, JH | 1 |
| Mahmud, I; Suzuki, H; Suzuki, T; Takahashi, Y; Yamamoto, S; Yamamoto, Y; Yoshimoto, T | 1 |
| Dai, W; Murphy, MJ | 1 |
| Hattori, T; Hieshima, K; Hirokawa, K; Miura, R; Nomiyama, H; Takatsuki, K | 1 |
| He, X; Konkle, BA; Liu, RJ; Mazur, EM; Schick, PK | 1 |
| Billia, F; Brady, G; Hoang, T; Iscove, NN; Kirsch, IR; Nakahara, K; Paradis, E | 1 |
| Erusalimsky, JD; Hong, Y; Martin, JF; Vainchenker, W | 1 |
| Boudignon-Proudhon, C; Parise, LV; Patel, PM | 1 |
| Cunningham, ML; Joneckis, CC; Orringer, EP; Parise, LV; Shock, DD | 1 |
| Tani, T; Virtanen, I; Ylänne, J | 1 |
| Cardie, J; Dai, W; Greenberg, JM; Li, B; Means, RT; Ouyang, B; Pan, HQ | 1 |
| Ansorge, S; Bohnensack, R; Fritz, S; Reinhold, D; Schlüter, T; Schönfeld, P; Striggow, F | 1 |
| Fahl, WE; Kujoth, GC; Liang, Y; Robinson, DF | 1 |
| Bardes, ES; Bell, RM; Buehrer, BM | 1 |
| Athanasiou, M; Blair, DG; Clausen, PA; Mavrothalassitis, GJ; Watson, DK; Zhang, XK | 1 |
| Mills, JC; Nachmias, VT; Niu, MY | 1 |
| Baliga, BS; Mankad, M; Mankad, VN; Shah, AK | 1 |
| Ahn, NG; Galasinski, SC; Nahreini, TS; Shapiro, PS; Whalen, AM | 1 |
| Fuse, A; Masumi-Fukazawa, A; Sato, K; Sato, T; Sunohara, M; Tanzawa, H; Yokoe, H | 1 |
| Figdor, CG; Lub, M; Oomen, SP; Pieters, RA; Robinson, M; van Kooyk, Y; van Vliet, SJ | 1 |
| Anagnostou, A; Ciaramella, JM; Li, W; Sigounas, G; Steiner, M | 1 |
| Fahl, WE; Kujoth, GC | 1 |
| Fields, AP; Murray, NR | 1 |
| Craston, R; Koh, M; Lowdell, MW; Mc Dermott, A; Prentice, HG; Ray, N | 1 |
| Decker, S; Herrera, R; Hubbell, S; Petruzzelli, L | 1 |
| Auberger, P; Belhacène, N; Cartron, JP; Colin, Y; Guérin, S; Mari, B; Maulon, L; Ricci, JE | 1 |
| Allsopp, RC; Chin, L; DePinho, RA; Greenberg, RA; Morin, GB | 1 |
| Ezawa, H; Harigaya, K; Ishii, G; Mikata, A; Nakajima, N | 1 |
| Fields, AP; Gökmen-Polar, Y | 1 |
| Eriksson, JE; Holmberg, CI; Lord, JM; Roos, PM; Sistonen, L | 1 |
| Aguirre, V; Beckman, BS; Liu, C; Mallia, CM; McGary, E; Noguchi, CT; Scandurro, AB; Tang, Y | 1 |
| Alastalo, TP; Nykanen, P; Pirkkala, L; Seppa, L; Sistonen, L | 1 |
| Block, MR; Molla, A | 1 |
| Drachman, JG; Kaushansky, K; Martin-Soudant, N; Nepveu, A | 1 |
| Aquino, A; Barrera, G; Dianzani, MU; Farace, MG; Fazio, VM; Pizzimenti, S; Rinaldi, M; Spinsanti, P | 1 |
| Algate, PA; Blalock, WL; Burrows, C; Franklin, R; Hoyle, PE; Lee, JT; McCubrey, JA; Moye, PW; Shelton, JG; Steelman, LS; Weinstein-Oppenheimer, C | 1 |
| Chang, SJ; Chen, HH; Lin, JS | 1 |
| Brodbeck, KC; Castronuevo, P; Petrushina, I; Schick, BP | 1 |
| Azzi, A; Breyer, I | 1 |
| Donin, N; Fishelson, Z; Jurianz, K; Kirschfink, M; Reiter, Y; Ziegler, S | 1 |
| Bianchi, L; Cellai, C; Della Malva, N; Laurenzana, A; Paoletti, F; Vannucchi, AM | 1 |
| Fibach, E; Marks, PA; Rifkind, RA; Weinstein, IB; Yamasaki, H | 2 |
| Fibach, E; Gambari, R; Maniatis, G; Marks, PA; Reuben, RC; Rifkind, RA; Sassa, S; Shaw, PA | 1 |
| Mufson, RA; Weinstein, IB; Yamasaki, H | 1 |
| Ishii, S; Masuda, M; Naito, M; Tsuruo, T | 1 |
| Schick, BP; Senkowski-Richardson, S | 1 |
| Grabarek, J; Kent, KC; Newman, PJ; Ravid, K; Raychowdhury, M; Ware, JA | 1 |
| Cohen, CM; GuptaRoy, B | 1 |
| Cuadrado, MA; Delgado, MD; Gómez-Casares, MT; León, J; Martínez, CA; Quincoces, AF; Richard, C | 1 |
| Busquets, X; Colomer, D; Kolesnick, RN; Marks, PA; Michaeli, J; Orlow, I; Rifkind, RA; Younes, A | 1 |
| Bertrand, O; Giroldi, L; Nakazawa, H; Sergeant, A; Yamasaki, H | 1 |
| Bolling, A; Hammarström, S; Söderström, M | 1 |
| Fields, AP; Hocevar, BA; Morrow, DM; Tykocinski, ML | 1 |
| Heldin, CH; Miyazono, K; Thyberg, J | 1 |
| Beckman, BS | 1 |
| Essex, DW; Konkle, BA; Rajagopalan, V; Shapiro, SS | 1 |
| Ihara, H; Kosaka, T; Miyata, A; Nüsing, R; Tanabe, T; Ullrich, V; Yokoyama, C | 1 |
| Ballestrero, A; Dallegri, F; Dapino, P; Ferrando, F; Ottonello, L; Patrone, F; Sacchetti, C | 1 |
| Chorváth, B; Fuchsberger, N; Sedlák, J | 1 |
| Andersson, LC; Järvinen, M; Virtanen, I | 1 |
| Cheresh, DA; Virtanen, I; Ylänne, J | 1 |
| Bailey, SC; Spangler, R; Sytkowski, AJ | 1 |
| Hirata, M; Nakajima, M; Narumiya, S; Okuma, M; Ushikubi, F | 1 |
| Fisher, CA; Hokom, MM; Hunt, P; Jacobsen, FW; Martin, FH; Wiemann, B | 1 |
| FitzGerald, GA; Funk, CD | 1 |
| Beckman, BS; Broadway, RL; George, WJ; Jeter, JR; Pincus, SM | 1 |
| Chen, ZX; Lebedev, YB; Marks, PA; Michaeli, J; Richon, VM; Rifkind, RA | 1 |
| Colosetti, P; Heldin, CH; Miyazono, K; Olofsson, A | 1 |
| Forget, BG; Lumelsky, NL | 1 |
| Ensor, CM; Tai, HH; Xun, CQ | 1 |
| Halenda, SP; Rehm, AG | 1 |
| Järvinen, M | 1 |
| Marks, PA; Rifkind, RA | 1 |
| Arcuri, RA; De Souza, MH; Marques-Silva, VM; Rumjanek, VM; Teixeira, MC | 1 |
| Arakawa, T; Suzuki, H; Tanabe, T; Toh, H; Yamamoto, S; Yamamoto, Y; Yokoyama, C; Yoshimoto, T | 1 |
| Kobayashi, E; Murakata, C; Nakano, H; Saitoh, H; Suzuki, K; Takahashi, I; Tamaoki, T | 1 |
| Eleouet, JF; Mignotte, V; Navarro, S; Romeo, PH; Zon, LI | 1 |
| Heffner, CH; Long, MW; Peters, C; Prochownik, EV; Williams, JL | 1 |
| Fisher, PB; Grant, S | 1 |
| Keeton, M; Oliver, LJ; Wilson, EL | 1 |
| Fujiwara, M; Nakajima, M; Narumiya, S; Okuma, M; Ushikubi, F; Yamamoto, M | 1 |
| Rohrschneider, LR; Symington, BE; Symington, FW | 1 |
| Ito, Y; Satake, M; Yamaguchi, Y | 1 |
| Bawden, L; Carne, A; Depledge, P; Meltzer, M; Newton, V; Sutton, C; Vodinelich, L | 1 |
| Altmeyer, A; Bischoff, P; Hauptmann, G; Moog, C; Waltzinger, C | 1 |
| Kondo, K; Oishi, M; Sasaki, H; Uehara, Y; Watanabe, T | 1 |
| Auwerx, JH; Chait, A; Deeb, SS; Wolfbauer, G | 1 |
| Marks, PA; Melloni, E; Patrone, M; Pontremoli, S; Rifkind, RA; Viotti, PL | 1 |
| Forsbeck, K; Gylfe, E; Larsson, R; Nilsson, K; Nilsson, M; Nygren, P | 1 |
| Adamson, JW; Broudy, VC; de Haën, C; Egrie, J; Lin, N; Papayannopoulou, T; Weiss, T | 1 |
| Kohno, H; Taketani, S; Tokunaga, R | 1 |
| Chen, RX; Du, CY; Liu, HT; Song, PG; Wang, XL; Xue, SB; You, JS; Zhang, HQ | 1 |
| Amadori, S; Bottero, L; Mandelli, F; Mastroberardino, G; Mavilio, F; Pelosi, E; Peschle, C; Petrini, M; Sposi, NM; Testa, U | 1 |
| Alitalo, K; Alitalo, R; Andersson, LC; Koskinen, P; Mäkelä, TP | 1 |
| Giroldi, L; Hollstein, M; Yamasaki, H | 1 |
| Damiani, G; Marks, PA; Melloni, E; Pontremoli, S; Rifkind, RA; Viotti, P; Weich, N | 1 |
| Kurachi, S; Messner, H; Nakamoto, B; Papayannopoulou, T; Tweeddale, M | 1 |
| Pályi, I | 1 |
| Järvinen, M; Vartio, T; Virtanen, I; Ylänne, J | 1 |
| Giroldi, L; Hamel, E; Yamasaki, H | 1 |
| Collins, S; Nakamoto, B; Papayannopoulou, T; Raines, E; Ross, R; Tweeddale, M | 1 |
| Eto, Y; Shibai, H; Takano, S; Takezawa, M; Tsuji, T; Yokogawa, Y | 1 |
| Cakiroglu, AG; Jackson, JF; Marks, PA; Melloni, E; Michetti, M; Pontremoli, S; Rifkind, RA; Sacco, O | 1 |
| Gavioli, R; Giuliani, AL; Spisani, S; Traniello, S | 1 |
| Griffin, J; Kufe, D; Mitchell, T; Sabbath, K; Sariban, E; Watanabe, T | 1 |
| Mitsuse, S; Oishi, M | 1 |
| Carthew, RW; Greenblatt, J; Sopta, M | 1 |
| Drexler, HG; Gaedicke, G; Martin, PJ; Minowada, J; Otsuka, K | 1 |
| Fukuda, M; Siebert, PD | 1 |
| Dinarello, CA; Kelley, V; Reddish, M; Rosenwasser, LJ; Strom, TB; Williams, JM | 1 |
| Arrow, AS; Faletto, DL; Macara, IG | 1 |
| Kufe, DW; Shafman, T; Watanabe, T | 1 |
5 review(s) available for tetradecanoylphorbol acetate and Di Guglielmo Disease
| Article | Year |
|---|---|
Induced differentiation of murine erythroleukemia cells: cellular and molecular mechanisms.
Topics: Animals; Cell Cycle; Cell Differentiation; Cell Division; Chromatin; DNA, Neoplasm; Genes; Globins; Leukemia, Erythroblastic, Acute; Leukemia, Experimental; Mice; Neoplasm Proteins; Phosphoproteins; RNA Processing, Post-Transcriptional; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53 | 1984 |
Commitment to terminal differentiation and the cell cycle.
Topics: Acetamides; Animals; Butyrates; Cell Cycle; Cell Differentiation; Cell Division; Dexamethasone; Dimethyl Sulfoxide; DNA Replication; Gene Expression Regulation; Globins; Hematopoietic Stem Cells; Hemin; Leukemia, Erythroblastic, Acute; Mice; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1982 |
In vitro studies on the mechanism of tumor promoter-mediated inhibition of cell differentiation.
Topics: Acetamides; Animals; Butyrates; Cell Adhesion; Cell Differentiation; Cell Division; Cell Line; Cell Membrane; Clone Cells; Diamines; Dimethyl Sulfoxide; Drug Resistance; Globins; Leukemia, Erythroblastic, Acute; Mice; Phorbol Esters; Phorbols; RNA, Messenger; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Time Factors | 1982 |
Approaches to more effective induction of cytodifferentiation of transformed cells and potential for cancer treatment.
Topics: Acetamides; Animals; Cell Differentiation; Humans; Leukemia, Erythroblastic, Acute; Neoplasms; Oncogenes; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vincristine | 1990 |
Effects of interferon on differentiation of normal and tumor cells.
Topics: Adipose Tissue; Animals; Cell Differentiation; Cells, Cultured; Dimethyl Sulfoxide; Hematopoiesis; Humans; Interferons; Leukemia; Leukemia, Erythroblastic, Acute; Melanins; Melanoma; Mice; Muscles; Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin | 1985 |
168 other study(ies) available for tetradecanoylphorbol acetate and Di Guglielmo Disease
| Article | Year |
|---|---|
Heparanase Facilitates PMA-Induced Megakaryocytic Differentiation in K562 Cells via Interleukin 6/STAT3 Pathway.
Topics: Carcinogenesis; Cell Differentiation; Extracellular Matrix; Feedback, Physiological; Fetal Blood; Glucuronidase; Heparitin Sulfate; Humans; Interleukin-6; K562 Cells; Leukemia, Erythroblastic, Acute; Megakaryocytes; Signal Transduction; STAT3 Transcription Factor; Tetradecanoylphorbol Acetate | 2020 |
Opposing regulation of megakaryopoiesis by LPA receptors 2 and 3 in K562 human erythroleukemia cells.
Topics: beta Catenin; GATA1 Transcription Factor; Humans; Integrin beta3; K562 Cells; Leukemia, Erythroblastic, Acute; Megakaryocytes; Microfilament Proteins; Reactive Oxygen Species; Receptors, Cytoplasmic and Nuclear; Receptors, Lysophosphatidic Acid; RNA Interference; Signal Transduction; Tetradecanoylphorbol Acetate; Thrombopoiesis; Time Factors; Trans-Activators; Transfection | 2015 |
Effects of extremely low frequency electromagnetic field (ELF-EMF) on catalase, cytochrome P450 and nitric oxide synthase in erythro-leukemic cells.
Topics: Catalase; Cytochrome P-450 Enzyme System; Electromagnetic Fields; Humans; K562 Cells; Leukemia, Erythroblastic, Acute; Nitric Oxide Synthase; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2015 |
Effects of azidothymidine on protein kinase C activity and expression in erythroleukemic cell K562 and acute lymphoblastic leukemia cell HSB-2.
Topics: Anti-HIV Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Synergism; Humans; Immunoblotting; K562 Cells; Leukemia, Erythroblastic, Acute; Membrane Fluidity; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protein Kinase C beta; Protein Kinase C-alpha; Tetradecanoylphorbol Acetate; Time Factors; Zidovudine | 2015 |
Dual mitochondrial localization and different roles of the reversible reaction of mammalian ferrochelatase.
Topics: Amino Acid Substitution; Animals; Base Sequence; Cell Line, Tumor; Chlorocebus aethiops; COS Cells; DNA Primers; Electrophoresis, Gel, Two-Dimensional; Ferrochelatase; Hemin; Humans; Hydrogen-Ion Concentration; Kidney; Leukemia, Erythroblastic, Acute; Mice; Microscopy, Immunoelectron; Mitochondria; Mitochondria, Liver; Mitochondrial Membranes; Mutagenesis, Site-Directed; Phosphorylation; Recombinant Proteins; Tetradecanoylphorbol Acetate; Transfection | 2009 |
RUNX1/core binding factor A2 regulates platelet 12-lipoxygenase gene (ALOX12): studies in human RUNX1 haplodeficiency.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Arachidonate 12-Lipoxygenase; Arachidonic Acid; Base Sequence; Binding Sites; Blood Platelets; Cell Line, Tumor; Chromatin Immunoprecipitation; Consensus Sequence; Core Binding Factor Alpha 2 Subunit; Electrophoretic Mobility Shift Assay; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Genes, Reporter; Haploidy; Humans; Leukemia, Erythroblastic, Acute; Luciferases; Molecular Sequence Data; Platelet Activation; Promoter Regions, Genetic; Protein Binding; RNA, Small Interfering; Tetradecanoylphorbol Acetate; Thrombin | 2010 |
Global analysis of in vivo EGR1-binding sites in erythroleukemia cell using chromatin immunoprecipitation and massively parallel sequencing.
Topics: Cell Line, Tumor; Chromatin Immunoprecipitation; Early Growth Response Protein 1; Gene Expression Regulation, Leukemic; Gene Regulatory Networks; Humans; Leukemia, Erythroblastic, Acute; Sequence Analysis, DNA; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factors | 2010 |
Prostacyclin receptor-dependent inhibition of human erythroleukemia cell differentiation is STAT3-dependent.
Topics: Cell Differentiation; Cell Line, Tumor; Cell Survival; Epoprostenol; Humans; Integrin beta3; Leukemia, Erythroblastic, Acute; Platelet Membrane Glycoprotein IIb; Receptors, Epoprostenol; Signal Transduction; STAT3 Transcription Factor; Tetradecanoylphorbol Acetate | 2012 |
Regulation of the human prostacyclin receptor gene in megakaryocytes: major roles for C/EBPδ and PU.1.
Topics: Cardiovascular Diseases; Cell Adhesion Molecules; Cell Differentiation; Cell Line, Tumor; Gene Expression Regulation; Humans; Leukemia, Erythroblastic, Acute; Megakaryocytes; Nectins; Octamer Transcription Factor-1; Promoter Regions, Genetic; Proto-Oncogene Proteins; Receptors, Epoprostenol; Receptors, Prostaglandin; Response Elements; Tetradecanoylphorbol Acetate; Trans-Activators | 2012 |
Characterization of a monoclonal antibody specific for a novel primate cell surface marker with distinct biochemical properties on human erythroleukemia and myeloid cell lines.
Topics: Animals; Antibodies, Monoclonal; Antibody Specificity; Biomarkers; Cell Line; Cell Membrane; Chlorocebus aethiops; Endopeptidase K; Epitopes; Humans; Hybridomas; Leukemia, Erythroblastic, Acute; Mice; Mice, Inbred BALB C; Tetradecanoylphorbol Acetate | 2002 |
NALP1 is a transcriptional target for cAMP-response-element-binding protein (CREB) in myeloid leukaemia cells.
Topics: Adaptor Proteins, Signal Transducing; Apoptosis Regulatory Proteins; Base Sequence; Binding Sites; Cell Line, Tumor; Cyclic AMP Response Element-Binding Protein; Gene Expression Regulation, Neoplastic; Hematopoietic Stem Cells; Humans; K562 Cells; Leukemia, Erythroblastic, Acute; Leukemia, Myeloid; Molecular Sequence Data; NLR Proteins; Promoter Regions, Genetic; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Transcription, Genetic | 2004 |
Expression of protease activated receptor 3 (PAR3) is upregulated by induction of megakaryocyte phenotype in human erythroleukemia (HEL) cells.
Topics: Cell Differentiation; Cell Line, Tumor; Cell Lineage; DNA; Gene Expression Regulation, Neoplastic; Humans; Leukemia, Erythroblastic, Acute; Megakaryocytes; Receptors, Cell Surface; Receptors, Proteinase-Activated; Receptors, Thrombin; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Up-Regulation | 2004 |
Diosgenin dose-dependent apoptosis and differentiation induction in human erythroleukemia cell line and sedimentation field-flow fractionation monitoring.
Topics: Apoptosis; Cell Differentiation; Cell Line, Tumor; Diosgenin; Fractionation, Field Flow; Humans; Leukemia, Erythroblastic, Acute; Staurosporine; Tetradecanoylphorbol Acetate | 2004 |
Down-regulation of EDAG expression by retrovirus-mediated small interfering RNA inhibits the growth and IL-8 production of leukemia cells.
Topics: Base Sequence; Cell Division; Cell Line, Tumor; Chromosome Mapping; Chromosomes, Human, Pair 9; Down-Regulation; Gene Expression Regulation, Neoplastic; Humans; Interleukin-8; Kinetics; Leukemia, Erythroblastic, Acute; Molecular Sequence Data; Nuclear Proteins; Retroviridae; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Tetradecanoylphorbol Acetate; Transfection | 2007 |
Inhibition of transferring binding and iron uptake of hematopoietic cell lines by phorbol esters.
Topics: Biological Transport; Cell Division; Cell Line; Hematopoietic Stem Cells; Humans; Iron; Kinetics; Leukemia, Erythroblastic, Acute; Phorbol Esters; Phorbols; Receptors, Cell Surface; Receptors, Transferrin; Tetradecanoylphorbol Acetate; Transferrin | 1984 |
Polyamine biosynthesis enzymes in the induction and inhibition of differentiation in Friend erythroleukemia cells.
Topics: Acetamides; Animals; Butyrates; Carboxy-Lyases; Cell Differentiation; Dexamethasone; Diamines; Dimethyl Sulfoxide; Enzyme Activation; Friend murine leukemia virus; Interferons; Leukemia, Erythroblastic, Acute; Leukemia, Experimental; Mice; Ornithine Decarboxylase; Polyamines; Tetradecanoylphorbol Acetate | 1980 |
Enhancement of viral gene expression in Friend erythroleukemic cells by 12-O tetradecanoylphorbol-13-acetate.
Topics: Cell Differentiation; Clone Cells; Dimethyl Sulfoxide; Friend murine leukemia virus; Genes, Viral; Leukemia, Erythroblastic, Acute; Neoplasms, Experimental; Phorbols; Plasminogen Activators; RNA-Directed DNA Polymerase; RNA, Viral; Tetradecanoylphorbol Acetate | 1980 |
Influence of 12-O-tetradecanoylphorbol-13-acetate (TPA) on the susceptibility of K562 to natural cytotoxicity: evidence for clonal variation in differentiation-induced changes of lytic sensitivity.
Topics: Cell Differentiation; Cell Line; Chromium Radioisotopes; Clone Cells; Cytotoxicity, Immunologic; Humans; Interferons; Karyotyping; Killer Cells, Natural; Leukemia, Erythroblastic, Acute; Phorbols; Tetradecanoylphorbol Acetate | 1984 |
Human erythroleukemia cell line (HEL) undergoes a drastic macrophage-like shift with TPA.
Topics: Acid Phosphatase; Antigens, Surface; Cell Adhesion; Cell Line; Erythrocytes; Esterases; Globins; Glycoproteins; Humans; Leukemia, Erythroblastic, Acute; Macrophages; Phagocytosis; Phenotype; Phorbols; Receptors, Cell Surface; Receptors, LDL; Tetradecanoylphorbol Acetate | 1983 |
Compared mechanisms of tumor cytolysis by human natural killer cells and activated polymorphonuclear leukocytes.
Topics: Catalase; Cell Line; Cytochrome c Group; Cytotoxicity, Immunologic; Humans; Killer Cells, Natural; Leukemia, Erythroblastic, Acute; Luminescent Measurements; Neutrophils; Phagocytosis; Plasmacytoma; Superoxide Dismutase; Tetradecanoylphorbol Acetate | 1984 |
Effects of dexamethasone and phorbol myristate acetate on the induction of differentiation in mouse erythroleukemic cells by dimethyl sulfoxide, proteases, and other compounds.
Topics: Animals; Cell Differentiation; Cell Division; Dactinomycin; Dexamethasone; Dimethyl Sulfoxide; Leukemia, Erythroblastic, Acute; Mice; Peptide Hydrolases; Phorbols; Tetradecanoylphorbol Acetate | 1983 |
Inhibition of dimethylsulfoxide-induced differentiation in Friend erythroleukemic cells by diacylglycerols and phospholipase C.
Topics: Animals; Cell Differentiation; Cell Line; Diglycerides; Dimethyl Sulfoxide; Friend murine leukemia virus; Glycerides; Kinetics; Leukemia, Erythroblastic, Acute; Leukemia, Experimental; Mice; Phospholipases; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1984 |
Biochemically-defined differentiation markers on human early haemopoietic (K562) cells.
Topics: Cell Differentiation; Cell Line; Glycoproteins; Hematopoietic Stem Cells; Hemin; Humans; Leukemia, Erythroblastic, Acute; Molecular Weight; Proteins; Tetradecanoylphorbol Acetate | 1984 |
Intercellular communication, cell differentiation and tumour promotion.
Topics: Amnion; Animals; Carcinogens; Cell Communication; Cell Differentiation; Cells, Cultured; Electric Conductivity; Female; Friend murine leukemia virus; Humans; Leukemia, Erythroblastic, Acute; Mice; Mice, Inbred BALB C; Neoplasms; Phorbol Esters; Phorbols; Pregnancy; Tetradecanoylphorbol Acetate | 1984 |
Phorbol ester tumor promoters block the transition from the early to the heme-dependent late program of Friend cell differentiation.
Topics: Animals; Cell Differentiation; Friend murine leukemia virus; Heme; Hemin; Kinetics; Leukemia, Erythroblastic, Acute; Mice; Phorbol Esters; Phorbols; Tetradecanoylphorbol Acetate | 1980 |
Cell cycle dependency of tumor promoter on murine erythroleukemic cells.
Topics: Animals; Benzidines; Butyrates; Butyric Acid; Cell Line; Cell Nucleus; Clone Cells; Dimethyl Sulfoxide; DNA; Interphase; Leukemia, Erythroblastic, Acute; Mice; Phorbols; Tetradecanoylphorbol Acetate | 1981 |
Effect of the tumor promoter 12-O-tetradecanoylphorbol-13-acetate on alpha-aminoisobutyrate uptake in friend Erythroleukemic cells.
Topics: Aminoisobutyric Acids; Animals; Biological Transport; Clone Cells; Friend murine leukemia virus; Leukemia, Erythroblastic, Acute; Leukemia, Experimental; Membrane Potentials; Phorbols; Potassium; Sodium; Tetradecanoylphorbol Acetate; Time Factors | 1981 |
Specific binding of phorbol esters to Friend erythroleukemia cells--general properties, down regulation and relationship to cell differentiation.
Topics: Animals; Binding Sites; Cell Differentiation; Diterpenes; Friend murine leukemia virus; Leukemia, Erythroblastic, Acute; Leukemia, Experimental; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Tetradecanoylphorbol Acetate; Tritium | 1982 |
Phorbol esters attenuate the expression of p53 in cells treated with doxorubicin and protect TS-P53/K562 from apoptosis.
Topics: Apoptosis; Cell Line; Cells, Cultured; Doxorubicin; Fibroblasts; Gene Expression; Genes, p53; Humans; Kinetics; Leukemia, Erythroblastic, Acute; Skin; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 1995 |
Changes in the components of a nuclear inositide cycle during differentiation in murine erythroleukaemia cells.
Topics: Animals; Blotting, Western; Cell Differentiation; Cell Nucleus; Diglycerides; Dimethyl Sulfoxide; Erythrocytes; G1 Phase; Hemoglobins; Leukemia, Erythroblastic, Acute; Mice; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Phosphatidylinositols; Phosphoric Diester Hydrolases; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Sustained c-kit expression in a human erythroleukemia cell line (HEL) after megakaryocytic differentiation induced by 12-O-tetradecanoylphorbol-13-acetate (TPA).
Topics: Base Sequence; Cell Differentiation; Cell Division; Cell Line; DNA Primers; Gene Expression Regulation, Neoplastic; Glycophorins; Hemoglobins; Humans; Kinetics; Leukemia, Erythroblastic, Acute; Megakaryocytes; Molecular Sequence Data; Oligonucleotides, Antisense; Platelet Membrane Glycoproteins; Polymerase Chain Reaction; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-kit; Proto-Oncogenes; Receptor Protein-Tyrosine Kinases; Receptors, Colony-Stimulating Factor; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Expression of mRNA for serglycin core protein and other platelet alpha granule proteins is increased in human erythroleukemia cells by phorbol myristate acetate.
Topics: Dimethyl Sulfoxide; Gene Expression Regulation, Leukemic; Humans; Leukemia, Erythroblastic, Acute; P-Selectin; Platelet Factor 4; Platelet Membrane Glycoproteins; Proteoglycans; RNA, Messenger; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta; Tumor Cells, Cultured; Up-Regulation; Vesicular Transport Proteins | 1993 |
Inhibition of the differentiation of human myeloid cell lines by redox changes induced through glutathione depletion.
Topics: Antigens, CD; Antigens, CD34; Base Sequence; Cell Adhesion; Cell Differentiation; DNA-Binding Proteins; Early Growth Response Protein 1; Glutathione; Granulocytes; Humans; Immediate-Early Proteins; Leukemia, Erythroblastic, Acute; Leukemia, Promyelocytic, Acute; Maleates; Molecular Sequence Data; Oxidation-Reduction; Peroxidase; Phenotype; Proto-Oncogene Proteins c-jun; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription Factors; Tumor Cells, Cultured | 1994 |
The proteoglycan perlecan is expressed in the erythroleukemia cell line K562 and is upregulated by sodium butyrate and phorbol ester.
Topics: Base Sequence; Butyrates; Butyric Acid; Cell Differentiation; Chondroitinases and Chondroitin Lyases; Glyceraldehyde-3-Phosphate Dehydrogenases; Heparan Sulfate Proteoglycans; Heparitin Sulfate; Humans; Immunoblotting; Leukemia, Erythroblastic, Acute; Leukemia, Promyelocytic, Acute; Molecular Sequence Data; Polysaccharide-Lyases; Proteoglycans; RNA; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Up-Regulation | 1995 |
Serglycin and betaglycan proteoglycans are expressed in the megakaryocytic cell line CHRF 288-11 and normal human megakaryocytes.
Topics: Base Sequence; Cell Line; DNA Primers; Fibronectins; Gene Expression; Humans; Leukemia, Erythroblastic, Acute; Megakaryocytes; Molecular Sequence Data; Protein Binding; Proteoglycans; Receptors, Transforming Growth Factor beta; RNA, Messenger; Tetradecanoylphorbol Acetate; Vesicular Transport Proteins | 1995 |
Protein kinase C chimeras: catalytic domains of alpha and beta II protein kinase C contain determinants for isotype-specific function.
Topics: Animals; Antineoplastic Agents; Baculoviridae; Base Sequence; Binding Sites; Bryostatins; Cell Division; Cell Line; DNA Primers; Humans; Isoenzymes; Lactones; Lamin Type B; Lamins; Leukemia, Erythroblastic, Acute; Macrolides; Mitogens; Molecular Sequence Data; Nuclear Proteins; Phosphorylation; Polymerase Chain Reaction; Protein Kinase C; Recombinant Fusion Proteins; Spodoptera; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1995 |
Identification and conditions for selective expression of megakaryocytic markers in Friend erythroleukemia cells.
Topics: Acetamides; Acetylcholinesterase; Animals; Biomarkers; Cell Differentiation; Fetal Blood; Flow Cytometry; Hemoglobins; Kinetics; Leukemia, Erythroblastic, Acute; Megakaryocytes; Mice; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Enhanced expression of the complement regulatory protein, membrane inhibitor of reactive lysis (CD59), is regulated at the level of transcription.
Topics: Antigens, CD; CD55 Antigens; CD59 Antigens; Cloning, Molecular; Gene Expression Regulation; Humans; In Vitro Techniques; Leukemia, Erythroblastic, Acute; Membrane Glycoproteins; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Time Factors; Transcription, Genetic; Tumor Cells, Cultured | 1993 |
Variation in the expression and/or phosphorylation of the human low molecular weight stress protein during in vitro cell differentiation.
Topics: Actins; Animals; Arsenites; Cell Differentiation; Cell Line; Cytoskeleton; Drosophila; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Gene Expression; Granulocytes; Heat-Shock Proteins; Hot Temperature; HSP30 Heat-Shock Proteins; Humans; Kinetics; Leucine; Leukemia, Erythroblastic, Acute; Leukemia, Promyelocytic, Acute; Megakaryocytes; Membrane Proteins; Mice; Molecular Weight; Phosphates; Phosphorylation; Sodium Compounds; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Identification and characterization of the human myeloperoxidase promoter.
Topics: Base Sequence; Chromosome Mapping; Dimethyl Sulfoxide; DNA, Neoplasm; Gene Deletion; Genetic Complementation Test; HeLa Cells; Humans; Introns; Leukemia, Erythroblastic, Acute; Leukemia, Myeloid, Acute; Molecular Sequence Data; Peroxidase; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Promoter Regions, Genetic; Sensitivity and Specificity; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1995 |
Human interleukin-3 receptor modulates bcl-2 mRNA and protein levels through protein kinase C in TF-1 cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Apoptosis; Base Sequence; Dactinomycin; Gene Expression Regulation, Leukemic; Humans; Interleukin-3; Isoquinolines; Leukemia, Erythroblastic, Acute; Molecular Sequence Data; Naphthalenes; Neoplasm Proteins; Piperazines; Protein Kinase C; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Receptors, Interleukin-3; RNA, Messenger; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1995 |
Constitutive c-myb expression in K562 cells inhibits induced erythroid differentiation but not tetradecanoyl phorbol acetate-induced megakaryocytic differentiation.
Topics: Base Sequence; Blotting, Western; Cell Differentiation; Cell Division; Cell Line; DNA Primers; DNA-Binding Proteins; DNA, Neoplasm; Erythrocytes; Gene Expression; Genetic Vectors; Humans; Leukemia, Erythroblastic, Acute; Megakaryocytes; Molecular Sequence Data; Oncogenes; Polymerase Chain Reaction; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myb; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1995 |
Brefeldin A down-regulates the transferrin receptor in K562 cells.
Topics: Brefeldin A; Cell Membrane; Cyclopentanes; Down-Regulation; Endocytosis; Exocytosis; Humans; Kinetics; Leukemia, Erythroblastic, Acute; Neoplasm Proteins; Receptors, Transferrin; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
A plant steroid, diosgenin, a new megakaryocytic differentiation inducer of HEL cells.
Topics: Cell Differentiation; Cell Line; Diosgenin; Humans; Kinetics; Leukemia, Erythroblastic, Acute; Megakaryocytes; Microscopy, Electron; Mitosis; Platelet Membrane Glycoproteins; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured | 1995 |
Changes in protein sulfation in human erythroleukemia (HEL), CHRF-288-11, and K562 cells following treatment with dimethyl sulfoxide or phorbol 12-myristate 13-acetate.
Topics: Dimethyl Sulfoxide; Humans; Leukemia, Erythroblastic, Acute; Molecular Weight; Neoplasm Proteins; Sulfates; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tunicamycin | 1995 |
Megakaryocyte-specific positive regulatory sequence 5' to the human PF4 gene.
Topics: Base Sequence; Chromosome Mapping; DNA; Enhancer Elements, Genetic; Gene Expression; Genes, Reporter; Humans; Leukemia, Erythroblastic, Acute; Luciferases; Megakaryocytes; Molecular Sequence Data; Platelet Factor 4; Promoter Regions, Genetic; Recombinant Fusion Proteins; Regulatory Sequences, Nucleic Acid; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1995 |
Two-step mechanism for actin polymerization in human erythroleukemia cells induced by phorbol ester.
Topics: Actins; Biopolymers; Cell Adhesion; Diglycerides; Enzyme Activation; Humans; Leukemia, Erythroblastic, Acute; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Differentiation of HL60 promyelocytic cells is promoted by a 'differentiation enhancing factor' produced by erythroleukemia cells.
Topics: Cell Differentiation; Cell Line; HMGB1 Protein; Humans; Isoenzymes; Kinetics; Leukemia, Erythroblastic, Acute; Leukemia, Promyelocytic, Acute; Neoplasm Proteins; Organothiophosphates; Protein Kinase C; Tetradecanoylphorbol Acetate; Time Factors; Tretinoin; Tumor Cells, Cultured | 1993 |
Expression and function of the cytoplasmic variants of the integrin alpha 6 subunit in transfected K562 cells. Activation-dependent adhesion and interaction with isoforms of laminin.
Topics: Cell Adhesion; Cell Adhesion Molecules; Cell Line; Cell Membrane; Cytoplasm; Gene Expression; Genetic Variation; Humans; Integrins; Kalinin; Kinetics; Laminin; Leukemia, Erythroblastic, Acute; Myocardium; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1993 |
Effect of 12-O-tetradecanoylphorbol-13-acetate on expression of cell surface antigens in two subclones of human leukemia K562 cells.
Topics: Antigens, Surface; Glycophorins; Humans; Leukemia, Erythroblastic, Acute; Macrophage-1 Antigen; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Establishment of a new cell line with the characteristics of a multipotential progenitor from a patient with chronic myelogenous leukemia in early erythroblastic crisis.
Topics: Aged; Antigens, Surface; Base Sequence; Blast Crisis; Cell Differentiation; Granulocytes; Hemoglobins; Histocytochemistry; Humans; Interleukin-3; Karyotyping; Leukemia, Erythroblastic, Acute; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Molecular Sequence Data; Peroxidase; Polymerase Chain Reaction; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Activity and protein distribution of 12-lipoxygenase in HEL cells: induction of membrane-association by phorbol ester TPA, modulation of activity by glutathione and 13-HPODE, and Ca(2+)-dependent translocation to membranes.
Topics: Arachidonate 12-Lipoxygenase; Biological Transport; Calcium; Cell Membrane; Cytosol; Dimethyl Sulfoxide; Glutathione; Humans; Immunoblotting; Leukemia, Erythroblastic, Acute; Linoleic Acids; Lipid Peroxides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
The effect of differentiation inducers on the integrin expression of K562 erythroleukemia cells.
Topics: Cell Adhesion; Cell Differentiation; Extracellular Matrix Proteins; Flow Cytometry; Humans; Integrins; Leukemia, Erythroblastic, Acute; Macromolecular Substances; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Protein kinase C isotypes in human erythroleukemia (K562) cell proliferation and differentiation. Evidence that beta II protein kinase C is required for proliferation.
Topics: Base Sequence; Butyrates; Butyric Acid; Cell Differentiation; Cell Division; Humans; Isoenzymes; Leukemia, Erythroblastic, Acute; Megakaryocytes; Molecular Sequence Data; Oligodeoxyribonucleotides; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
The role of phosphorylation in activation of the alpha 6A beta 1 laminin receptor.
Topics: Amino Acid Sequence; Base Sequence; DNA; Humans; Laminin; Leukemia, Erythroblastic, Acute; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphorylation; Phosphoserine; Protein Kinase C; Receptors, Laminin; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1993 |
Induction of apolipoprotein E expression during erythroid differentiation of human K562 leukemia cells.
Topics: Apolipoproteins E; Cell Differentiation; Cytarabine; Humans; Hydroxyurea; Hypercholesterolemia; Leukemia, Erythroblastic, Acute; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
The major regulatory element upstream of the alpha-globin gene has classical and inducible enhancer activity.
Topics: Base Sequence; beta-Galactosidase; Cell Differentiation; Chloramphenicol O-Acetyltransferase; Gene Expression Regulation; Globins; HeLa Cells; Hemin; Humans; Leukemia, Erythroblastic, Acute; Molecular Sequence Data; Promoter Regions, Genetic; Regulatory Sequences, Nucleic Acid; RNA, Messenger; Simian virus 40; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1993 |
Changes in mechanisms of monocyte/macrophage-mediated cytotoxicity during culture. Reactive oxygen intermediates are involved in monocyte-mediated cytotoxicity, whereas reactive nitrogen intermediates are employed by macrophages in tumor cell killing.
Topics: Arginine; Cells, Cultured; Cytotoxicity, Immunologic; DNA, Neoplasm; Humans; Leukemia, Erythroblastic, Acute; Luminescent Measurements; Macrophages; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Nitric Oxide; Nitrites; omega-N-Methylarginine; Reactive Oxygen Species; Superoxides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Induction of cyclooxygenase and suppression of 12-lipoxygenase in human erythroleukemia cells upon phorbol ester-induced differentiation.
Topics: Arachidonate 12-Lipoxygenase; Arachidonic Acid; Cell Adhesion; Cell Division; Dose-Response Relationship, Drug; Enzyme Induction; Humans; Leukemia, Erythroblastic, Acute; Prostaglandin-Endoperoxide Synthases; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Downregulation of GATA-1 expression during phorbol myristate acetate-induced megakaryocytic differentiation of human erythroleukemia cells.
Topics: Base Sequence; Cell Differentiation; DNA-Binding Proteins; Down-Regulation; Erythroid-Specific DNA-Binding Factors; GATA1 Transcription Factor; Gene Expression Regulation; Glycophorins; Humans; Leukemia, Erythroblastic, Acute; Megakaryocytes; Molecular Sequence Data; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription Factors; Tumor Cells, Cultured | 1993 |
Characterization of cytokine LD78 gene promoters: positive and negative transcriptional factors bind to a negative regulatory element common to LD78, interleukin-3, and granulocyte-macrophage colony-stimulating factor gene promoters.
Topics: Animals; Base Sequence; Cell Nucleus; Chemokine CCL3; Chemokine CCL4; Chloramphenicol O-Acetyltransferase; Cytokines; DNA Probes; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-3; Leukemia, Erythroblastic, Acute; Leukemia, T-Cell; Luciferases; Macrophage Inflammatory Proteins; Methylation; Mice; Molecular Sequence Data; Monokines; Mutagenesis, Site-Directed; Neoplasm Proteins; Oligodeoxyribonucleotides; Promoter Regions, Genetic; Regulatory Sequences, Nucleic Acid; Restriction Mapping; Sequence Deletion; Sequence Homology, Nucleic Acid; Tetradecanoylphorbol Acetate; Transcription Factors; Transfection; Tumor Cells, Cultured | 1993 |
Plasminogen activator inhibitor-1 mRNA is expressed in platelets and megakaryocytes and the megakaryoblastic cell line CHRF-288.
Topics: Animals; Blood Platelets; Blotting, Northern; Blotting, Western; Guinea Pigs; Humans; Leukemia, Erythroblastic, Acute; Megakaryocytes; Plasminogen Activator Inhibitor 1; Polymerase Chain Reaction; Precipitin Tests; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Opposing effects of the basic helix-loop-helix transcription factor SCL on erythroid and monocytic differentiation.
Topics: Adult; Aminolevulinic Acid; Base Sequence; Basic Helix-Loop-Helix Transcription Factors; Cell Differentiation; Cell Lineage; DNA-Binding Proteins; DNA, Complementary; Erythrocytes; Erythroid Precursor Cells; Erythropoietin; Granulocyte-Macrophage Colony-Stimulating Factor; Helix-Loop-Helix Motifs; Hematopoietic Stem Cells; Humans; Leukemia, Erythroblastic, Acute; Molecular Sequence Data; Monocytes; Polymerase Chain Reaction; Proto-Oncogene Proteins; Recombinant Proteins; T-Cell Acute Lymphocytic Leukemia Protein 1; Tetradecanoylphorbol Acetate; Transcription Factors; Transfection; Tumor Cells, Cultured | 1996 |
Inhibition of protein kinase C suppresses megakaryocytic differentiation and stimulates erythroid differentiation in HEL cells.
Topics: Aphidicolin; Biomarkers; Blood Proteins; Cell Cycle; Cell Differentiation; Enzyme Inhibitors; Erythroid Precursor Cells; Gene Expression Regulation, Leukemic; Globins; Glycophorins; Hematopoietic Stem Cells; Hemin; Humans; Indoles; Leukemia, Erythroblastic, Acute; Maleimides; Megakaryocytes; Neoplasm Proteins; Phorbol 12,13-Dibutyrate; Phosphoproteins; Phosphorylation; Platelet Membrane Glycoproteins; Protein Kinase C; Protein Processing, Post-Translational; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1996 |
Phorbol ester enhances integrin alpha IIb beta 3-dependent adhesion of human erythroleukemic cells to activation-dependent monoclonal antibodies.
Topics: Amino Acid Sequence; Antibodies, Monoclonal; Antigen-Antibody Reactions; Cell Adhesion; Fibrinogen; Humans; Leukemia, Erythroblastic, Acute; Molecular Sequence Data; Neoplasm Proteins; Neoplastic Stem Cells; Peptide Fragments; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Binding; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1996 |
Glycoprotein IV-independent adhesion of sickle red blood cells to immobilized thrombospondin under flow conditions.
Topics: Aggrecans; Amino Acid Sequence; Anemia, Sickle Cell; Antibodies, Monoclonal; CD36 Antigens; Cell Adhesion; Collagen; Erythrocytes, Abnormal; Extracellular Matrix Proteins; Fibronectins; Humans; Integrin alpha4beta1; Integrins; Lectins, C-Type; Leukemia, Erythroblastic, Acute; Membrane Glycoproteins; Molecular Sequence Data; Proteoglycans; Receptors, Lymphocyte Homing; Rheology; Tetradecanoylphorbol Acetate; Thrombospondins; Tumor Cells, Cultured; Vitronectin | 1996 |
Expression of megakaryocytic and erythroid properties in human leukemic cells.
Topics: Antigens, CD; Antigens, Differentiation; Antigens, Differentiation, Myelomonocytic; Antigens, Neoplasm; Antigens, Surface; Blood Platelets; Blood Proteins; Cell Adhesion Molecules; Cell Differentiation; Erythrocyte Membrane; Erythrocytes; Flow Cytometry; Hematopoietic Cell Growth Factors; Hematopoietic Stem Cells; Humans; Leukemia; Leukemia, Erythroblastic, Acute; Megakaryocytes; Membrane Glycoproteins; Microscopy, Fluorescence; Neoplasm Proteins; Neoplastic Stem Cells; Platelet Endothelial Cell Adhesion Molecule-1; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1996 |
Expression of receptor protein tyrosine kinase tif is regulated during leukemia cell differentiation.
Topics: Acetamides; Base Sequence; Cell Differentiation; Down-Regulation; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Leukemic; Humans; Leukemia; Leukemia, Erythroblastic, Acute; Leukemia, Megakaryoblastic, Acute; Molecular Sequence Data; Phosphorylation; Receptor Protein-Tyrosine Kinases; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1996 |
Phorbol ester-induced shedding of intercellular adhesion molecule-1 (ICAM-1) on erythroleukemic K 562 cells.
Topics: Blotting, Western; Cell Line; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Fluorescent Antibody Technique, Indirect; Gene Expression; Humans; Intercellular Adhesion Molecule-1; Kinetics; Leukemia, Erythroblastic, Acute; Microscopy, Fluorescence; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1996 |
Functional analysis of the SIS proximal element and its activating factors: regulated transcription of the c-SIS/PDGF-B gene in human erythroleukemia cells.
Topics: Base Sequence; Cell Differentiation; DNA-Binding Proteins; Humans; Leukemia, Erythroblastic, Acute; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Platelet-Derived Growth Factor; Protein Binding; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-sis; Sp1 Transcription Factor; Sp3 Transcription Factor; Tetradecanoylphorbol Acetate; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured | 1996 |
Protein kinase C-dependent regulation of human erythroleukemia (HEL) cell sphingosine kinase activity.
Topics: Cell Differentiation; Dimethyl Sulfoxide; Enzyme Activation; Enzyme Inhibitors; Humans; Kinetics; Leukemia, Erythroblastic, Acute; Naphthalenes; Phosphotransferases (Alcohol Group Acceptor); Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1996 |
Increased expression of the ETS-related transcription factor FLI-1/ERGB correlates with and can induce the megakaryocytic phenotype.
Topics: Animals; Antigens, CD; Cell Adhesion; Cell Differentiation; Cell Division; DNA-Binding Proteins; G1 Phase; Gene Expression Regulation, Developmental; Genetic Vectors; Hemoglobins; Humans; Integrin alpha2; Leukemia, Erythroblastic, Acute; Megakaryocytes; Mice; Platelet Glycoprotein GPIIb-IIIa Complex; Proto-Oncogene Protein c-fli-1; Proto-Oncogene Proteins; Resting Phase, Cell Cycle; Retroviridae; RNA, Messenger; Tetradecanoylphorbol Acetate; Trans-Activators; Tumor Cells, Cultured | 1996 |
Development of polarity in human erythroleukemia cells: roles of membrane ruffling and the centrosome.
Topics: Bucladesine; Cell Membrane; Cell Polarity; Cell Size; Centrosome; Humans; Leukemia, Erythroblastic, Acute; Microtubules; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1997 |
Mechanism of differentiation of human erythroleukaemic cell line K562 by hemin.
Topics: Cell Differentiation; Cell Line; Dimethyl Sulfoxide; Erythropoietin; Hemin; Humans; Interleukin-3; Leukemia, Erythroblastic, Acute; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Megakaryocytic differentiation induced by constitutive activation of mitogen-activated protein kinase kinase.
Topics: Base Sequence; Cell Differentiation; Cell Division; DNA Primers; Enzyme Activation; Erythropoiesis; Gene Expression; Globins; Humans; Leukemia, Erythroblastic, Acute; Megakaryocytes; Mitogen-Activated Protein Kinase Kinases; Mutation; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Kinases; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1997 |
Induction of polyploidization in the human erythroleukemia cell line (HEL) by protein kinase inhibitor (K252a) and the phorbol-ester TPA.
Topics: Antigens, CD34; Carbazoles; Carcinogens; CDC2 Protein Kinase; cdc25 Phosphatases; Cell Cycle; Cell Cycle Proteins; Cyclins; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; Indole Alkaloids; Leukemia, Erythroblastic, Acute; Phosphoprotein Phosphatases; Platelet Glycoprotein GPIIb-IIIa Complex; Polyploidy; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1997 |
Cytoplasmic tails of beta 1, beta 2, and beta 7 integrins differentially regulate LFA-1 function in K562 cells.
Topics: Amino Acid Sequence; Binding Sites; CD18 Antigens; Cell Adhesion; Cell Membrane; Cytoplasm; Fibronectins; Humans; Integrin beta Chains; Integrin beta1; Integrins; Intercellular Adhesion Molecule-1; Leukemia, Erythroblastic, Acute; Leukemia, Experimental; Lymphocyte Function-Associated Antigen-1; Lymphocytes; Molecular Sequence Data; Recombinant Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1997 |
dl-alpha-tocopherol, a potent inhibitor of phorbol ester induced shape change of erythro- and megakaryoblastic leukemia cells.
Topics: Arachidonic Acid; Cell Adhesion; Cell Membrane; Cell Size; Cytosol; Dose-Response Relationship, Drug; Humans; Leukemia, Erythroblastic, Acute; Leukemia, Megakaryoblastic, Acute; Protein Kinase C; Pseudopodia; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vitamin E | 1997 |
c-sis/platelet-derived growth factor-B promoter requirements for induction during the 12-O-tetradecanoylphorbol-13-acetate-mediated megakaryoblastic differentiation of K562 human erythroleukemia cells.
Topics: Base Sequence; Cell Differentiation; Gene Expression Regulation, Leukemic; Humans; Leukemia, Erythroblastic, Acute; Megakaryocytes; Molecular Sequence Data; Platelet-Derived Growth Factor; Promoter Regions, Genetic; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-sis; Sequence Deletion; TATA Box; Tetradecanoylphorbol Acetate; Transcription Factors; Tumor Cells, Cultured | 1997 |
Atypical protein kinase C iota protects human leukemia cells against drug-induced apoptosis.
Topics: Antineoplastic Agents; Apoptosis; Cell Division; Drug Resistance, Neoplasm; Humans; Isoenzymes; Leukemia, Erythroblastic, Acute; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1997 |
Temporal dynamics of CD69 expression on lymphoid cells.
Topics: Antigens, CD; Antigens, Differentiation, T-Lymphocyte; CD3 Complex; Cytotoxicity, Immunologic; Flow Cytometry; Humans; Interleukin-12; Isoantigens; Killer Cells, Natural; Lectins, C-Type; Leukemia, Erythroblastic, Acute; Phytohemagglutinins; Stimulation, Chemical; T-Lymphocytes; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured | 1997 |
A role for the MEK/MAPK pathway in PMA-induced cell cycle arrest: modulation of megakaryocytic differentiation of K562 cells.
Topics: Calcium-Calmodulin-Dependent Protein Kinases; Cell Adhesion; Cell Adhesion Molecules; Cell Cycle; Cell Differentiation; Cytoskeletal Proteins; Enzyme Inhibitors; Fibronectins; Flavonoids; Humans; Leukemia, Erythroblastic, Acute; MAP Kinase Kinase Kinase 1; Megakaryocytes; Mitogen-Activated Protein Kinase 1; Paxillin; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1998 |
Differential expression of the Kell blood group and CD10 antigens: two related membrane metallopeptidases during differentiation of K562 cells by phorbol ester and hemin.
Topics: Antigens, CD; Cell Differentiation; Cell Division; Cell Membrane; Gene Expression Regulation, Neoplastic; Hemin; Humans; Kell Blood-Group System; Kinetics; Leukemia, Erythroblastic, Acute; Neprilysin; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 1998 |
Expression of mouse telomerase reverse transcriptase during development, differentiation and proliferation.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Base Sequence; Cell Differentiation; Cells, Cultured; Cellular Senescence; Chromosome Mapping; DNA-Binding Proteins; DNA, Complementary; Down-Regulation; Gene Expression Regulation, Developmental; Gene Expression Regulation, Neoplastic; Humans; Leukemia, Erythroblastic, Acute; Mice; Mice, Inbred C57BL; Mitogens; Molecular Sequence Data; Nucleoproteins; Proteins; RNA; RNA, Long Noncoding; RNA, Untranslated; Sequence Homology, Amino Acid; Spleen; Telomerase; Tetradecanoylphorbol Acetate; Tissue Distribution; Tumor Cells, Cultured | 1998 |
12-O-tetradecanoylphorbol-13-acetate (TPA) downregulates expression of CD30 in erythroleukemia cell line K562.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Antigens, Neoplasm; Blast Crisis; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Inhibitors; Gene Expression Regulation, Leukemic; Half-Life; Humans; Ki-1 Antigen; Leukemia, Erythroblastic, Acute; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Nucleic Acid Synthesis Inhibitors; Protein Kinase C; Protein Synthesis Inhibitors; RNA, Messenger; RNA, Neoplasm; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1997 |
Mapping of a molecular determinant for protein kinase C betaII isozyme function.
Topics: Base Sequence; Enzyme Activation; Gene Expression Regulation, Enzymologic; Humans; Isoenzymes; Lamin Type B; Lamins; Leukemia, Erythroblastic, Acute; Models, Molecular; Molecular Sequence Data; Nuclear Proteins; Peptide Fragments; Phosphatidylglycerols; Phosphorylation; Protein Binding; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-alpha; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1998 |
Conventional and novel PKC isoenzymes modify the heat-induced stress response but are not activated by heat shock.
Topics: Carcinogens; Cell Nucleus; Enzyme Activation; Enzyme Inhibitors; Heat-Shock Response; HeLa Cells; Humans; Indoles; Isoenzymes; Leukemia, Erythroblastic, Acute; Maleimides; Nuclear Localization Signals; Protein Kinase C; RNA, Messenger; Tetradecanoylphorbol Acetate | 1998 |
Protein kinase calpha is an effector of hexamethylene bisacetamide-induced differentiation of Friend erythroleukemia cells.
Topics: Acetamides; Animals; Cell Differentiation; Friend murine leukemia virus; Globins; Humans; Isoenzymes; Leukemia, Erythroblastic, Acute; Mice; Oligonucleotides, Antisense; Protein Kinase C; Protein Kinase C-alpha; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1999 |
Differentiation lineage-specific expression of human heat shock transcription factor 2.
Topics: Cell Differentiation; Cell Lineage; Erythropoiesis; Gene Expression Regulation, Developmental; Heat-Shock Proteins; Hematopoietic Stem Cells; Hemin; Humans; Leukemia, Erythroblastic, Acute; Megakaryocytes; Promoter Regions, Genetic; RNA Processing, Post-Transcriptional; Tetradecanoylphorbol Acetate; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured | 1999 |
Adherence of human erythroleukemia cells inhibits proliferation without inducing differentiation.
Topics: Cell Adhesion; Cell Differentiation; Cell Division; Extracellular Matrix Proteins; Fibronectins; Humans; Integrin alpha4beta1; Integrins; Leukemia, Erythroblastic, Acute; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Neoplasm Proteins; Protein Kinase C; Receptors, Fibronectin; Receptors, Lymphocyte Homing; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2000 |
CDP/Cut DNA binding activity is down-modulated in granulocytes, macrophages and erythrocytes but remains elevated in differentiating megakaryocytes.
Topics: Animals; Bone Marrow Cells; Cell Differentiation; Drosophila melanogaster; Drosophila Proteins; Erythrocytes; Granulocytes; Hematopoietic Stem Cells; Homeodomain Proteins; Humans; K562 Cells; Leukemia, Erythroblastic, Acute; Macrophages; Megakaryocytes; Mice; Mice, Inbred Strains; Nerve Tissue Proteins; Nuclear Proteins; Repressor Proteins; Tetradecanoylphorbol Acetate; Transcription Factors; Tumor Cells, Cultured | 2000 |
4-Hydroxynonenal-induced MEL cell differentiation involves PKC activity translocation.
Topics: Aldehydes; Animals; Biological Transport, Active; Cell Differentiation; Cell Division; Dimethyl Sulfoxide; Enzyme Inhibitors; Hemoglobins; Indoles; Leukemia, Erythroblastic, Acute; Maleimides; Mice; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2000 |
Effects of deregulated Raf activation on integrin, cytokine-receptor expression and the induction of apoptosis in hematopoietic cells.
Topics: Animals; Apoptosis; CD11 Antigens; Cell Aggregation; Cell Differentiation; Cell Size; DNA Replication; DNA, Complementary; Enzyme Activation; Estradiol; Gene Expression Regulation; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Integrins; Interleukin-3; Leukemia, Erythroblastic, Acute; MAP Kinase Kinase Kinases; MAP Kinase Signaling System; Mice; Mice, Inbred DBA; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Myeloid Progenitor Cells; Neoplasm Proteins; Phosphorylation; Protein Processing, Post-Translational; Protein Subunits; Proto-Oncogene Proteins c-raf; Receptors, Cytokine; Receptors, Estrogen; Recombinant Fusion Proteins; Tamoxifen; Tetradecanoylphorbol Acetate; Transfection; Tretinoin; Tumor Cells, Cultured | 2000 |
Alpha-tocopherol downregulates the expression of GPIIb promoter in HEL cells.
Topics: Chloramphenicol O-Acetyltransferase; Down-Regulation; Gene Expression Regulation, Neoplastic; Genes, Reporter; Humans; Leukemia, Erythroblastic, Acute; Megakaryocytes; Platelet Aggregation; Platelet Glycoprotein GPIb-IX Complex; Platelet Membrane Glycoproteins; Polymerase Chain Reaction; Promoter Regions, Genetic; Restriction Mapping; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured; Vitamin E | 2000 |
Promoter regulatory elements and DNase I-hypersensitive sites involved in serglycin proteoglycan gene expression in human erythroleukemia, CHRF 288-11, and HL-60 cells.
Topics: Bucladesine; Deoxyribonuclease I; Gene Expression Regulation, Neoplastic; Helix-Loop-Helix Motifs; HL-60 Cells; Humans; Introns; Leukemia, Erythroblastic, Acute; Megakaryocytes; Promoter Regions, Genetic; Proteoglycans; RNA, Messenger; Tetradecanoylphorbol Acetate; Vesicular Transport Proteins | 2001 |
Differential inhibition by alpha- and beta-tocopherol of human erythroleukemia cell adhesion: role of integrins.
Topics: Antibodies, Monoclonal; Cell Adhesion; Down-Regulation; Flavonoids; Flow Cytometry; Humans; Integrins; Isoenzymes; K562 Cells; Leukemia, Erythroblastic, Acute; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Naphthalenes; Neoplasm Proteins; Phosphorylation; Protein Kinase C; Protein Kinase C-alpha; Protein Processing, Post-Translational; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; U937 Cells; Vitamin E | 2001 |
K562 erythroleukemic cells are equipped with multiple mechanisms of resistance to lysis by complement.
Topics: alpha-Amylases; Antigens, CD; CD55 Antigens; CD59 Antigens; Cell Membrane; Complement Activation; Complement System Proteins; Dose-Response Relationship, Drug; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Erythrocytes; Flow Cytometry; Humans; K562 Cells; Leukemia, Erythroblastic, Acute; Membrane Cofactor Protein; Membrane Glycoproteins; Naphthalenes; Neutrophils; Plant Proteins; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Trypsin Inhibitors; Tumor Necrosis Factor-alpha | 2001 |
Specific PAF antagonist WEB-2086 induces terminal differentiation of murine and human leukemia cells.
Topics: Animals; Antineoplastic Agents; Azepines; Cell Differentiation; Cell Division; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Histones; HL-60 Cells; Humans; K562 Cells; Kinetics; Leukemia; Leukemia, Erythroblastic, Acute; Mice; Phospholipid Ethers; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Triazoles; Tumor Cells, Cultured | 2002 |
Heterogeneity of murine erythroleukemia cells with respect to tumor promoter-mediated inhibition of cell differentiation.
Topics: Anesthetics; Animals; Clone Cells; Dexamethasone; Diterpenes; Drug Resistance; Erythropoiesis; Leukemia, Erythroblastic, Acute; Leukemia, Experimental; Mice; Phenotype; Phorbols; Tetradecanoylphorbol Acetate | 1978 |
Tumor promoter-induced adhesion of the DS19 clone of murine erythroleukemia cells.
Topics: Animals; Cell Adhesion; Cell Differentiation; Clone Cells; Cold Temperature; Dactinomycin; Drug Resistance; Kinetics; Leukemia, Erythroblastic, Acute; Leukemia, Experimental; Mice; Phorbol Esters; Phorbols; Tetradecanoylphorbol Acetate | 1979 |
Tumor promoter-mediated inhibition of cell differentiation: suppression of the expression of erythroid functions in murine erythroleukemia cells.
Topics: Cell Differentiation; Cell Division; Cell Line; Globins; Heme; Kinetics; Leukemia, Erythroblastic, Acute; Phorbols; Protein Biosynthesis; RNA, Messenger; Spectrin; Tetradecanoylphorbol Acetate | 1979 |
Phorbol ester induced prostaglandin synthesis and [3H]-TPA metabolism by TPA-sensitive and TPA-resistant Friend erythroleukemia cells.
Topics: Arachidonic Acids; Cell Line; Clone Cells; Kinetics; Leukemia, Erythroblastic, Acute; Phorbol Esters; Phorbols; Prostaglandins E; Prostaglandins F; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1979 |
Expression of 85-kDa protein of adriamycin-resistant tumor cells during hematopoietic differentiation of THP-1 and HEL cells.
Topics: Antigens, CD; Antigens, Differentiation, Myelomonocytic; Cell Adhesion Molecules; Cell Differentiation; Doxorubicin; Drug Resistance; Humans; Leukemia, Erythroblastic, Acute; Leukemia, Myelomonocytic, Acute; Lipopolysaccharide Receptors; Megakaryocytes; Membrane Proteins; Monocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1992 |
Proteoglycan synthesis in human erythroleukaemia (HEL) cells.
Topics: Blood Platelets; Cell Division; Chromatography; Culture Media; Dimethyl Sulfoxide; Humans; Leukemia, Erythroblastic, Acute; Megakaryocytes; P-Selectin; Platelet Membrane Glycoproteins; Proteoglycans; Sepharose; Sulfur Radioisotopes; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured | 1992 |
Identification and functional characterization of protein kinase C isozymes in platelets and HEL cells.
Topics: Base Sequence; Blood Platelets; Calcium; Cell Line; Chromatography; Durapatite; Humans; Hydroxyapatites; Immunoblotting; Isoenzymes; Leukemia, Erythroblastic, Acute; Molecular Sequence Data; Neoplasm Proteins; Oligodeoxyribonucleotides; Phosphorylation; Protein Kinase C; RNA; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Thrombin | 1992 |
Maturation of murine erythroleukemia cells committed to differentiation requires protein kinase C.
Topics: Actins; Animals; Anion Exchange Protein 1, Erythrocyte; Blotting, Northern; Cell Differentiation; Cell Membrane; Globins; Leukemia, Erythroblastic, Acute; Mice; Phosphoproteins; Protein Kinase C; Receptors, Fibronectin; Receptors, Immunologic; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
Differential expression of ras protooncogenes during in vitro differentiation of human erythroleukemia cells.
Topics: Cell Differentiation; Cytarabine; Gene Expression Regulation, Leukemic; Genes, ras; Humans; Leukemia, Erythroblastic, Acute; Macrophages; Megakaryocytes; RNA, Messenger; Tetradecanoylphorbol Acetate | 1992 |
A rise and fall in 1,2-diacylglycerol content signal hexamethylene bisacetamide-induced erythropoiesis.
Topics: Acetamides; Animals; Diglycerides; Drug Resistance; Erythropoiesis; Genetic Variation; Kinetics; Leukemia, Erythroblastic, Acute; Mice; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vincristine | 1992 |
Role of activator protein-1 and methylation function in 12-O-tetradecanoylphorbol-13-acetate--mediated inhibition of differentiation of Friend erythroleukemia cells.
Topics: Animals; Base Sequence; Cell Differentiation; Electrophoresis, Polyacrylamide Gel; Friend murine leukemia virus; Gene Expression Regulation; Globins; Leukemia, Erythroblastic, Acute; Methylation; Mice; Molecular Sequence Data; Proto-Oncogene Proteins c-jun; Tetradecanoylphorbol Acetate; Transcriptional Activation; Transfection; Tumor Cells, Cultured | 1992 |
Induction of leukotriene C4 synthase activity in differentiating human erythroleukemia cells.
Topics: Calcitriol; Cell Differentiation; Dimethyl Sulfoxide; Enzyme Induction; Glutathione Transferase; Humans; Kinetics; Leukemia, Erythroblastic, Acute; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1992 |
Protein kinase C isotypes in human erythroleukemia cell proliferation and differentiation.
Topics: Bryostatins; Cell Division; Enzyme Activation; Erythropoiesis; Humans; Immunoblotting; Isoenzymes; Kinetics; Lactones; Lamins; Leukemia, Erythroblastic, Acute; Macrolides; Nuclear Proteins; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
Retention of the transforming growth factor-beta 1 precursor in the Golgi complex in a latent endoglycosidase H-sensitive form.
Topics: Animals; Cell Line; DNA Replication; Fluorescent Antibody Technique; Golgi Apparatus; Humans; Leukemia, Erythroblastic, Acute; Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase; Models, Biological; Protein Precursors; Recombinant Proteins; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta | 1992 |
Nuclear protein kinase C activity is decreased in Friend erythroleukemia cells induced to differentiate.
Topics: Acetamides; Alkaloids; Cell Division; Cell Nucleus; Cell Transformation, Viral; Dimethyl Sulfoxide; DNA; Friend murine leukemia virus; Hematinics; Humans; Leukemia, Erythroblastic, Acute; Protein Kinase C; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Thymidine; Tritium; Tumor Cells, Cultured | 1992 |
Tumor necrosis factor-alpha modulation of glycoprotein Ib alpha expression in human endothelial and erythroleukemia cells.
Topics: Blotting, Western; Cells, Cultured; Endothelium, Vascular; Gene Expression; Humans; In Vitro Techniques; Interferon-gamma; Interleukin-1; Leukemia, Erythroblastic, Acute; Platelet Membrane Glycoproteins; Recombinant Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Tumor Necrosis Factor-alpha | 1992 |
Induction of thromboxane synthase and prostaglandin endoperoxide synthase mRNAs in human erythroleukemia cells by phorbol ester.
Topics: Cyclooxygenase Inhibitors; Enzyme Induction; Humans; Kinetics; Leukemia, Erythroblastic, Acute; RNA, Messenger; Tetradecanoylphorbol Acetate; Thromboxane-A Synthase; Tumor Cells, Cultured | 1992 |
Tumor cell lysis by activated human neutrophils: analysis of neutrophil-delivered oxidative attack and role of leukocyte function-associated antigen 1.
Topics: Antibodies, Monoclonal; Burkitt Lymphoma; Cell Aggregation; Cells, Cultured; Cytotoxicity, Immunologic; Humans; Hydrogen Peroxide; Hypochlorous Acid; Leukemia, Erythroblastic, Acute; Lymphocyte Function-Associated Antigen-1; Neutrophils; Oxidation-Reduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
Interferon alpha-induced modulation of leukocyte cell surface antigens: immunocytofluorometric study with human leukaemia/lymphoma cell lines.
Topics: Antigens, CD; Antigens, Differentiation; Antigens, Neoplasm; Antigens, Surface; Gene Expression Regulation, Neoplastic; Humans; Interferon alpha-2; Interferon-alpha; Leukemia, Erythroblastic, Acute; Leukemia, Promyelocytic, Acute; Leukocytes; Lymphoma, Large B-Cell, Diffuse; Neprilysin; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Receptors, Transferrin; Recombinant Proteins; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
K562 erythroleukemia cells express cytokeratins 8, 18, and 19 and epithelial membrane antigen that disappear after induced differentiation.
Topics: Blotting, Western; Breast Neoplasms; Butyrates; Butyric Acid; Cell Differentiation; Epithelial Cells; Fluorescent Antibody Technique; Hemin; Humans; In Vitro Techniques; Keratins; Leukemia, Erythroblastic, Acute; Membrane Glycoproteins; Mucin-1; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Localization of beta 1, beta 3, alpha 5, alpha v, and alpha IIb subunits of the integrin family in spreading human erythroleukemia cells.
Topics: Cell Adhesion; Cell Movement; Fibronectins; Fluorescent Antibody Technique; Glass; Glycoproteins; Humans; Integrins; Leukemia, Erythroblastic, Acute; Membrane Glycoproteins; Peptide Fragments; Tetradecanoylphorbol Acetate; Thrombospondins; Tumor Cells, Cultured; Vitronectin | 1990 |
Erythropoietin induces cytosolic protein phosphorylation and dephosphorylation in erythroid cells.
Topics: Animals; Cell Line; Cytosol; Erythropoietin; Female; Hematopoietic Stem Cells; Kinetics; Leukemia, Erythroblastic, Acute; Leukemia, Experimental; Mice; Mice, Inbred Strains; Molecular Weight; Peptide Fragments; Phosphates; Phosphopeptides; Phosphoproteins; Phosphorylation; Spleen; Tetradecanoylphorbol Acetate | 1991 |
Purification and characterization of the human platelet TXA2/PGH2 receptor.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Binding, Competitive; Blood Platelets; Bridged Bicyclo Compounds; Cell Membrane; Fatty Acids, Monounsaturated; Humans; Leukemia, Erythroblastic, Acute; Neoplasm Proteins; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins H; Receptors, Prostaglandin; Receptors, Thromboxane; Receptors, Thromboxane A2, Prostaglandin H2; Tetradecanoylphorbol Acetate; Thromboxane A2; Tumor Cells, Cultured | 1991 |
Platelet factor 4 mRNA expression in human erythroleukemic cells: regulation by phorbol esters and certain cytokines.
Topics: Antigens, Surface; Blood Platelets; Cell Line; Cycloheximide; Cytokines; DNA; Gene Expression; Humans; Leukemia, Erythroblastic, Acute; Platelet Factor 4; Platelet Membrane Glycoproteins; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta | 1991 |
Eicosanoid forming enzyme mRNA in human tissues. Analysis by quantitative polymerase chain reaction.
Topics: Actins; Arachidonate 12-Lipoxygenase; Arachidonate 15-Lipoxygenase; Arachidonate 5-Lipoxygenase; Asthma; Base Sequence; Blood Platelets; Bronchoalveolar Lavage Fluid; Epoxide Hydrolases; Erythrocytes; Humans; Leukemia, Erythroblastic, Acute; Leukocytes; Molecular Sequence Data; Plasmids; Polymerase Chain Reaction; Prostaglandin-Endoperoxide Synthases; Reticulocytes; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
Early changes in phosphoprotein patterns of Friend erythroleukaemia cells induced by dimethylsulphoxide or phorbol esters.
Topics: Animals; Calcimycin; Cell Differentiation; Cyclic AMP; Cyclic GMP; Dimethyl Sulfoxide; Friend murine leukemia virus; Kinetics; Leukemia, Erythroblastic, Acute; Mice; Phosphoproteins; Phosphorylation; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Conversion of differentiation inducer resistance to differentiation inducer sensitivity in erythroleukemia cells.
Topics: Acetamides; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Differentiation; Cell Line; Cycloheximide; Dexamethasone; Drug Resistance; Kinetics; Leukemia, Erythroblastic, Acute; Leukemia, Experimental; Membrane Glycoproteins; Mice; Neoplasm Proteins; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Verapamil; Vinblastine; Vincristine | 1990 |
A role of the latent TGF-beta 1-binding protein in the assembly and secretion of TGF-beta 1.
Topics: Carrier Proteins; Humans; Hydrolysis; Intracellular Signaling Peptides and Proteins; Latent TGF-beta Binding Proteins; Leukemia, Erythroblastic, Acute; Molecular Weight; Precipitin Tests; Protein Precursors; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta; Trypsin; Tumor Cells, Cultured | 1991 |
Negative regulation of globin gene expression during megakaryocytic differentiation of a human erythroleukemic cell line.
Topics: Cell Differentiation; Cell Nucleus; Gene Expression Regulation, Neoplastic; Globins; Humans; Leukemia, Erythroblastic, Acute; Megakaryocytes; Phenotype; Plasmids; Restriction Mapping; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection | 1991 |
Regulation of synthesis and activity of NAD(+)-dependent 15-hydroxy-prostaglandin dehydrogenase (15-PGDH) by dexamethasone and phorbol ester in human erythroleukemia (HEL) cells.
Topics: Blotting, Western; Carcinogens; Cell Line; Dexamethasone; Dinoprostone; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Humans; Hydroxyprostaglandin Dehydrogenases; Kinetics; Leukemia, Erythroblastic, Acute; Methionine; NAD; Phorbol Esters; Steroids; Sulfur Radioisotopes; Tetradecanoylphorbol Acetate | 1991 |
Evidence for the calcium-dependent activation of phospholipase D in thrombin-stimulated human erythroleukaemia cells.
Topics: Adenosine Diphosphate; Calcimycin; Calcium; Cell Line; Enzyme Activation; Epinephrine; Glycerophospholipids; Humans; Kinetics; Leukemia, Erythroblastic, Acute; Myristic Acid; Myristic Acids; Phosphatidic Acids; Phosphatidylinositols; Phospholipase D; Phospholipases; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Thrombin; Tumor Cells, Cultured | 1990 |
Vimentin in human erythroleukemia (HEL) cells is modulated with differentiation inducers.
Topics: Butyrates; Butyric Acid; Cell Differentiation; Cytoskeleton; Fluorescent Antibody Technique; Hemin; Humans; Immunohistochemistry; Intermediate Filaments; Leukemia, Erythroblastic, Acute; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured; Vimentin | 1990 |
Myeloid leukemia differentiation by phorbol ester and retinoic acid: a practical approach.
Topics: Cell Transformation, Neoplastic; Diagnosis, Differential; Humans; Leukemia, Erythroblastic, Acute; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid; Leukemia, Promyelocytic, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tetradecanoylphorbol Acetate; Tretinoin | 1990 |
Molecular cloning and expression of human arachidonate 12-lipoxygenase.
Topics: Amino Acid Sequence; Arachidonate 12-Lipoxygenase; Arachidonate 15-Lipoxygenase; Arachidonate 5-Lipoxygenase; Base Sequence; Chromatography, High Pressure Liquid; Cloning, Molecular; Dimethyl Sulfoxide; DNA; Gene Expression Regulation, Enzymologic; Genomic Library; Humans; Leukemia, Erythroblastic, Acute; Molecular Sequence Data; Open Reading Frames; Restriction Mapping; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Potent selective inhibition of 7-O-methyl UCN-01 against protein kinase C.
Topics: Alkaloids; Animals; Antineoplastic Agents; Cell Survival; Cells, Cultured; Enzyme Activation; Kinetics; Leukemia, Erythroblastic, Acute; Mice; Protein Kinase C; Protein Kinase Inhibitors; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
The extinction of erythroid genes after tetradecanoylphorbol acetate treatment of erythroleukemic cells correlates with down-regulation of the tissue-specific factors NF-E1 and NF-E2.
Topics: Base Sequence; Cell Line; DNA-Binding Proteins; Erythroid-Specific DNA-Binding Factors; Gene Expression; Humans; Hydroxymethylbilane Synthase; Kinetics; Leukemia, Erythroblastic, Acute; Molecular Sequence Data; NF-E2 Transcription Factor; NF-E2 Transcription Factor, p45 Subunit; Oligonucleotide Probes; Promoter Regions, Genetic; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription Factors; Zinc Fingers | 1990 |
Regulation of megakaryocyte phenotype in human erythroleukemia cells.
Topics: Antigens; Cell Differentiation; Cell Division; Cell Fusion; Humans; Interphase; Leukemia, Erythroblastic, Acute; Megakaryocytes; Phenotype; Phorbol 12,13-Dibutyrate; Protein Kinase C; Proto-Oncogene Mas; Proto-Oncogenes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Regulation and secretion of plasminogen activators and their inhibitors in a human leukemic cell line (K562).
Topics: Cell Differentiation; Cell Division; Cell Line; Glycoproteins; Humans; Kinetics; Leukemia, Erythroblastic, Acute; Plasminogen Inactivators; Tetradecanoylphorbol Acetate; Tissue Plasminogen Activator; Tumor Cells, Cultured; Urokinase-Type Plasminogen Activator | 1989 |
Expression of thromboxane A2 receptor in cultured human erythroleukemia cells and its induction by 12-O-tetradecanoylphorbol-13-acetate.
Topics: Animals; Bridged Bicyclo Compounds; Dactinomycin; Fatty Acids, Monounsaturated; Humans; Iodine Radioisotopes; Kinetics; Leukemia; Leukemia, Erythroblastic, Acute; Mice; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins H; Receptors, Prostaglandin; Receptors, Thromboxane; Tetradecanoylphorbol Acetate; Thromboxane A2; Tumor Cells, Cultured | 1989 |
Phorbol ester induces increased expression, altered glycosylation, and reduced adhesion of K562 erythroleukemia cell fibronectin receptors.
Topics: Cell Adhesion; Cell Line; Chromatography, Affinity; Electrophoresis, Polyacrylamide Gel; Fibronectins; Glycosylation; Humans; Kinetics; Leukemia, Erythroblastic, Acute; Neuraminidase; Phorbol Esters; Receptors, Fibronectin; Receptors, Immunologic; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
Two overlapping sequence motifs within the polyomavirus enhancer are independently the targets of stimulation by both the tumor promoter 12-O-tetradecanoylphorbol-13-acetate and the Ha-ras oncogene.
Topics: Animals; Cattle; Colforsin; Cycloheximide; Enhancer Elements, Genetic; Gene Expression Regulation; Genes, ras; Leukemia, Erythroblastic, Acute; Polyomavirus; Regulatory Sequences, Nucleic Acid; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 1989 |
Purification and sequencing of glycosylation variants of BSF-1, as a MAF, from the EL-4 leukaemia cell line.
Topics: Amino Acid Sequence; Animals; Glycosylation; Interleukin-4; Interleukins; Leukemia, Erythroblastic, Acute; Lymphokines; Macrophage-Activating Factors; Molecular Sequence Data; Molecular Weight; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
In vitro modulation of leucocyte-function-associated antigen-1 expression on two leukemic cell lines.
Topics: Antigens, Differentiation; Cell Line; Cytotoxicity, Immunologic; Humans; Immunity, Cellular; Kinetics; Leukemia, Erythroblastic, Acute; Leukemia, T-Cell; Lymphocyte Activation; Lymphocyte Function-Associated Antigen-1; T-Lymphocytes, Cytotoxic; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
Induction of in vitro differentiation of mouse embryonal carcinoma (F9) and erythroleukemia (MEL) cells by herbimycin A, an inhibitor of protein phosphorylation.
Topics: Animals; Benzoquinones; Cell Differentiation; Dexamethasone; Enzyme Induction; Gene Expression Regulation; Globins; Lactams, Macrocyclic; Leukemia, Erythroblastic, Acute; Mice; Phosphoproteins; Phosphorylation; Plasminogen Activators; Quinones; Rifabutin; Teratoma; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
Loss of copper-zinc superoxide dismutase gene expression in differentiated cells of myelo-monocytic origin.
Topics: Cell Differentiation; Cell Line; Diglycerides; Gene Expression; Genes; Humans; Kinetics; Leukemia, Erythroblastic, Acute; Leukemia, Promyelocytic, Acute; Macrophages; Monocytes; RNA, Messenger; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1989 |
Differential expression of protein kinase C isozymes and erythroleukemia cell differentiation.
Topics: Acetamides; Animals; Calcium; Cell Differentiation; Drug Resistance; Genetic Variation; Isoenzymes; Leukemia, Erythroblastic, Acute; Mice; Phospholipids; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vincristine | 1989 |
Cytoplasmic pH is differently regulated in the monoblastic U-937 and erythroleukemic K-562 cell lines.
Topics: Calcium; Carrier Proteins; Cell Compartmentation; Cell Line; Cytoplasm; Ethers; Humans; Hydrogen-Ion Concentration; Ionomycin; Leukemia, Erythroblastic, Acute; Leukemia, Experimental; Microscopy, Electron; Monocytes; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate | 1988 |
Identification of the receptor for erythropoietin on human and murine erythroleukemia cells and modulation by phorbol ester and dimethyl sulfoxide.
Topics: Animals; Cell Line; Dimethyl Sulfoxide; Erythropoietin; Humans; Kinetics; Leukemia, Erythroblastic, Acute; Mice; Molecular Weight; Receptors, Cell Surface; Receptors, Erythropoietin; Recombinant Proteins; Tetradecanoylphorbol Acetate | 1988 |
Tumor-promoting, phorbol ester-induced phosphorylation of cell-surface transferrin receptors in human erythroleukemia cells.
Topics: Animals; Antibodies, Monoclonal; Cell Line; Cell Membrane; Electrophoresis, Polyacrylamide Gel; Humans; Leukemia, Erythroblastic, Acute; Mice; Phorbols; Phosphorylation; Receptors, Cell Surface; Receptors, Transferrin; Tetradecanoylphorbol Acetate; Transferrin | 1985 |
[Relationship between expression of c-myc and P53 genes and terminal differentiation during induced differentiation in Friend erythroleukemia cells].
Topics: Animals; Cell Differentiation; Cell Division; Cell Line; Friend murine leukemia virus; Gene Expression Regulation; Genes; Leukemia, Erythroblastic, Acute; Mice; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myc; Tetradecanoylphorbol Acetate | 1988 |
Expression of c-fos in human normal and neoplastic monocyte-macrophage differentiation.
Topics: Calcitriol; Cell Differentiation; Gene Expression Regulation; Humans; Leukemia; Leukemia, Erythroblastic, Acute; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Macrophages; Monocytes; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1987 |
Enhanced expression of transforming growth factor beta during megakaryoblastic differentiation of K562 leukemia cells.
Topics: Cell Line; Cell Transformation, Neoplastic; Cycloheximide; Humans; Leukemia, Erythroblastic, Acute; Leukemia, Megakaryoblastic, Acute; Neoplasm Proteins; Peptide Biosynthesis; Peptides; Platelet-Derived Growth Factor; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Transforming Growth Factors; Tumor Cells, Cultured | 1988 |
Cellular-oncogene expression in Friend erythroleukemia cells: relationship to differentiation, commitment and TPA effects.
Topics: Cell Differentiation; Friend murine leukemia virus; Leukemia, Erythroblastic, Acute; Proto-Oncogenes; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1988 |
Vincristine-resistant erythroleukemia cell line has marked increased sensitivity to hexamethylenebisacetamide-induced differentiation.
Topics: Acetamides; Animals; Cell Differentiation; Cell Division; Dexamethasone; Drug Resistance; Erythropoiesis; Globins; Hemoglobins; Leukemia, Erythroblastic, Acute; Mice; Protein Kinase C; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vincristine | 1988 |
Surface antigenic profile and globin phenotype of two new human erythroleukemia lines: characterization and interpretations.
Topics: Antigens, Surface; Cell Line; Clone Cells; Culture Media; Globins; Growth Substances; Hematopoietic Stem Cells; Heme; Histocytochemistry; Humans; Leukemia, Erythroblastic, Acute; Male; Middle Aged; Phenotype; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1988 |
Heterogeneity of the response to inducers of differentiation and to cytostatics of tumor cell populations.
Topics: Antineoplastic Agents; Cell Differentiation; Cisplatin; Cytarabine; Dacarbazine; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Doxorubicin; Fluorouracil; Humans; Leukemia, Erythroblastic, Acute; Leukemia, Promyelocytic, Acute; Melanoma; Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1988 |
Tumor promoter and fibronectin induce actin stress fibers and focal adhesion sites in spreading human erythroleukemia (HEL) cells.
Topics: Actins; Autoradiography; Cell Adhesion; Cytoskeleton; Electrophoresis, Polyacrylamide Gel; Fibroblasts; Fibronectins; Fluorescent Antibody Technique; Humans; Immunoassay; Leukemia, Erythroblastic, Acute; Phenotype; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1987 |
1-Oleoyl 2-acetyl glycerol inhibits differentiation of TPA-sensitive but not of TPA-resistant Friend cells.
Topics: Acetamides; Animals; Cell Adhesion; Cell Differentiation; Diglycerides; Dose-Response Relationship, Drug; Drug Resistance; Friend murine leukemia virus; Glycerides; Leukemia, Erythroblastic, Acute; Phorbols; Protein Kinase C; Tetradecanoylphorbol Acetate | 1986 |
Constitutive and inducible secretion of platelet-derived growth factor analogs by human leukemic cell lines coexpressing erythroid and megakaryocytic markers.
Topics: Cell Differentiation; Cell Line; Erythrocytes; Hematopoietic Stem Cells; Humans; Kinetics; Leukemia, Erythroblastic, Acute; Megakaryocytes; Platelet Membrane Glycoproteins; Platelet-Derived Growth Factor; RNA, Messenger; Tetradecanoylphorbol Acetate | 1987 |
Purification and characterization of erythroid differentiation factor (EDF) isolated from human leukemia cell line THP-1.
Topics: Activins; Amino Acid Sequence; Animals; Cell Differentiation; Cell Line; Friend murine leukemia virus; Humans; Inhibins; Leukemia; Leukemia, Erythroblastic, Acute; Leukemia, Experimental; Macromolecular Substances; Mice; Molecular Weight; Neoplasm Proteins; Peptide Fragments; Tetradecanoylphorbol Acetate | 1987 |
Protein kinase C activity and hexamethylenebisacetamide-induced erythroleukemia cell differentiation.
Topics: Acetamides; Animals; Calcium; Cell Differentiation; Cells, Cultured; Hemoglobins; Leukemia, Erythroblastic, Acute; Leupeptins; Mice; Phospholipids; Protein Kinase C; Tetradecanoylphorbol Acetate | 1987 |
[Tumoricidal activity of neutrophils].
Topics: Cell Line; Cytotoxicity, Immunologic; Humans; Leukemia, Erythroblastic, Acute; Neutrophils; Oxygen; Tetradecanoylphorbol Acetate | 1987 |
Effects of 1-beta-D-arabinofuranosylcytosine and phorbol ester on differentiation of human K562 erythroleukemia cells.
Topics: Cell Differentiation; Cell Line; Cytarabine; DNA Replication; Globins; Glycophorins; Heme; Humans; Kinetics; Leukemia, Erythroblastic, Acute; Leukemia, Myeloid; Nucleic Acid Hybridization; Phorbols; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1985 |
Induction of a novel nuclear protein (p54) by phorbol esters in mouse erythroleukemia (Friend) cells.
Topics: Animals; Cell Differentiation; Cell Line; Drug Resistance; Friend murine leukemia virus; Leukemia, Erythroblastic, Acute; Leukemia, Experimental; Methionine; Mice; Nucleoproteins; Phorbols; Tetradecanoylphorbol Acetate | 1985 |
Isolation of three proteins that bind to mammalian RNA polymerase II.
Topics: Adrenal Cortex Neoplasms; Animals; Carrier Proteins; Cattle; Cell Line; Cell Nucleus; Chromatography, Affinity; Dimethyl Sulfoxide; HeLa Cells; Humans; Leukemia, Erythroblastic, Acute; Leukemia, Experimental; Ligands; Mice; Molecular Weight; Phosphoproteins; Protein Binding; RNA Polymerase II; Subcellular Fractions; Tetradecanoylphorbol Acetate; Thymus Gland | 1985 |
Changes in isoenzyme patterns expressed by the erythroleukemia cell lines K-562 and HEL after induction of differentiation.
Topics: Cell Differentiation; Cell Line; Glycoproteins; Growth Inhibitors; Humans; Interleukin-6; Isoenzymes; Leukemia Inhibitory Factor; Leukemia, Erythroblastic, Acute; Leukemia, Myeloid; Lymphokines; Tetradecanoylphorbol Acetate | 1985 |
Positive and negative regulation of specific gene expression by the tumor promoter TPA in human erythroleukemic K562 cells.
Topics: Actins; Cell Line; Electrophoresis, Polyacrylamide Gel; Gene Expression Regulation; Glycophorins; Humans; Leukemia, Erythroblastic, Acute; Phorbols; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Vimentin | 1985 |
Phorbol myristate acetate-protein complex mimics bioactivity of human IL-1. 1. Direct evidence that PMA temporarily enters and is released from cellular compartment during superinduction protocol.
Topics: Animals; Binding, Competitive; Cell Compartmentation; Cell Line; Dinoprostone; Humans; Immune Sera; Interleukin-1; Leukemia P388; Leukemia, Erythroblastic, Acute; Leukemia, Experimental; Lymphocyte Activation; Macrophages; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Neoplasm Proteins; Phorbols; Phytohemagglutinins; Prostaglandins E; Pyrogens; Rabbits; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1985 |
An early decrease in phosphatidylinositol turnover occurs on induction of Friend cell differentiation and precedes the decrease in c-myc expression.
Topics: Animals; Cell Differentiation; Cell Line; Diglycerides; Dimethyl Sulfoxide; Erythrocytes; Erythropoiesis; Friend murine leukemia virus; Glycerol; Hemoglobins; Inositol; Inositol Phosphates; Leukemia, Erythroblastic, Acute; Mice; Phosphatidylinositols; Proto-Oncogene Proteins; Proto-Oncogenes; RNA, Messenger; Tetradecanoylphorbol Acetate; Triglycerides | 1985 |
Requirement of spermidine for induction of both heme synthesis and globin transcription in murine erythroleukemia cells.
Topics: Animals; Cell Division; Dexamethasone; Dimethyl Sulfoxide; Eflornithine; Globins; Heme; Leukemia, Erythroblastic, Acute; Mice; Ornithine; Spermidine; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1985 |