tetradecanoylphorbol acetate has been researched along with Contact Dermatitis in 92 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (10.87) | 18.7374 |
| 1990's | 33 (35.87) | 18.2507 |
| 2000's | 17 (18.48) | 29.6817 |
| 2010's | 24 (26.09) | 24.3611 |
| 2020's | 8 (8.70) | 2.80 |
| Authors | Studies |
|---|---|
| Fernandez, JR; Fitzgerald, C; Perez, E; Rouzard, K; Savile, C; Tamura, M | 1 |
| Feng, X; Guo, P; Hu, L; Huang, J; Li, M; Li, Y; Sun, M; Wang, X; Wu, J; Yu, H; Zeng, J; Zhang, J; Zhang, S | 1 |
| Alves, APNN; Nunes, PIG; Santos, FA; Santos, SMD; Sasahara, GL; Silveira, ER; Viana, AFSC | 1 |
| Hashimoto, K; Matsumoto, T; Nakamura, A; Nozawa, N; Uratsuji, H; Yamada, Y | 1 |
| Assreuy, J; Bresolin, TMB; Cabrini, DA; Farias, IV; Ferreira, BGA; Horinouchi, CDDS; Krueger, CMA; Mendes, DAGB; Meyre-Silva, C; Otuki, MF; Soley, BDS; Zuffellato-Ribas, KC | 1 |
| Baretta, IP; Brandenburg, MM; Cabrini, DA; Costa, SCA; Meinerz, CC; Otuki, MF; Pawloski, PL; Rocha, FG; Soley, BDS | 1 |
| Ascari, J; Cabrini, DA; Cretella, ABM; Otuki, MF; Pawloski, PL; Ruziska, RM; Scharf, DR; Soley, BDS | 1 |
| Gomez, LA; Perez, JJ; Porras, M | 1 |
| Demidov, ON; Goloudina, AR; Grigorash, BB; Kochetkova, EY; Uyanik, B | 1 |
| Kojima, Y; Nakamura, T; Yasoshima, M; Yoshida, N | 1 |
| Chen, F; Fu, R; Guo, YR; Huang, QL; Peng, T; Tang, L; Xu, Y; Zhang, YT | 1 |
| Nakae, D; Nakajima, J; Yasukawa, K | 1 |
| Bahrami, S; Duch, M; Funding, A; Iversen, L; Johansen, C; Pedersen, FS; Toft, L; Tolstrup, M; Østergaard, L | 1 |
| Choi, SY; Eum, WS; Han, KH; Jeong, HJ; Jo, HS; Kim, DS; Kim, DW; Kim, HA; Kim, MJ; Park, EY; Park, J; Park, JH; Sohn, EJ; Son, O | 1 |
| Guan, X; Guo, J; Han, Q; Li, B; Wang, L; Zhang, H; Zhang, M; Zhou, J | 1 |
| Ahn, SK; Hong, SP; Jeon, JE; Jeong, SK; Kim, B; Kim, HJ; Lee, SH; Mann, S; Park, BM | 1 |
| Libert, C; Sklyarova, T; van Hengel, J; van Roy, F; Van Wonterghem, E; Vandenbroucke, RE | 1 |
| Gao, Z; Rakariyatham, K; Song, M; Wang, M; Wu, X; Xiao, H; Xu, F; Zheng, J | 1 |
| Jaks, V; Kingo, K; Klaas, M; Langel, K; Langel, Ü; Lorents, A; Maimets, T; Padari, K; Pooga, M; Rebane, A; Runnel, T; Tkaczyk, E; Urgard, E; Viil, J | 1 |
| Brito, PS; Cabrini, DA; Facundo, VA; Favero, GM; Horinouchi, CD; Mendes, DA; Nolte, S; Otuki, MF; Santos, AR; Soley, BD | 1 |
| Brito, GA; Calou, IB; Cunha, GM; Rao, VS; Santos, FA; Silveira, ER; Sousa, DI | 1 |
| Han, MH; Han, SB; Jeong, SK; Kang, JS; Kim, HM; Lee, CW; Lee, H; Lee, K; Moon, EY; Park, BD; Park, SK; Yang, KH; Yoon, WK; Youm, JK | 1 |
| Han, G; Han, MH; Han, SB; Jeong, SK; Kang, JS; Kim, HM; Lee, CW; Lee, H; Lee, K; Park, BD; Park, SK; Youm, JK | 1 |
| Chandler, PR; Duhadaway, JB; Everhart, ME; Johnson, BA; Kahler, DJ; Mellor, AL; Muller, AJ; Munn, DH; Pihkala, J; Prendergast, GC; Sharma, MD; Soler, AP | 1 |
| Dellinger, A; Kepley, CL; Lenk, R; MacFarland, D; Zhou, Z | 1 |
| Hirasawa, N; Hong, J; Ishihara, K; Ohsawa, Y; Ohuchi, K; Seyama, T | 1 |
| Bailey, K; Blumberg, H; Dean, C; Dinh, H; Holland, PM; Peschon, JJ; Rountree, RB; Willis, CR | 1 |
| Asadullah, K; Becker, A; Buchmann, B; Döcke, WD; Friedrich, A; Gaestel, M; Grütz, G; Mengel, A; Naundorf, S; Röse, L; Schottelius, AJ; Zollner, TM; Zügel, U | 1 |
| Andrade, GM; Brito, GA; Carvalho, KM; Morais, TC; Pessoa, OD; Pinto, NB; Rao, VS; Santos, FA; Silva, CR; Veras, ML | 1 |
| Cheng, AC; Kuo, DH; Lai, YS; Lo, CY; Pan, MH; Wu, H | 1 |
| Choi, G; Choo, BK; Kim, HK; Lee, AY; Lee, DY; Yoon, T | 1 |
| Boller, S; Cabrini, DA; Marques, MC; Otuki, MF; Pizzolatti, MG; Santos, EP; Soldi, C; Zampronio, AR | 1 |
| Cužić, S; Eraković Haber, V; Ivetić Tkalčević, V; Kramarić, MD; Parnham, MJ | 1 |
| Meretski, S; Otuki, MF; Rosenblat, G; Schwob, O; Segal, J; Silveira Prudente, A; Yedgar, S; Zaltsman, I | 1 |
| Chen, YJ; Huang, CY; Lin, SY; Palanisamy, A; Sheu, JH; Wei, WC; Wen, CC; Yang, NS | 1 |
| Clarke, M; Das, S; Huels, D; Jamieson, T; Jung, A; Neumann, J; Nibbs, RJ; Olson, MF; Samuel, MS; Sansom, OJ; Steele, CW | 1 |
| Cabrini, DA; Facundo, VA; Horinouchi, CD; Mendes, DA; Otuki, MF; Pietrovski, EF; Santos, AR; Soley, Bda S | 1 |
| Gao, ZF; Guo, J; Li, LF | 1 |
| Fukuda, Y; Murakawa, M; Tanaka, Y; Yamaoka, K | 1 |
| Ha, HY; Kim, TY; Kim, Y; Ryoo, ZY | 1 |
| Avellar, MC; Calixto, JB; Medeiros, R; Otuki, MF | 1 |
| Babad, JM; Garay, M; Liebel, FT; Southall, MD; Sur, R | 1 |
| Edamatsu, H; Hu, L; Ikuta, S; Kataoka, T; Li, M | 1 |
| Chang, S; Demerjian, M; Elias, PM; Feingold, KR; Lee, SH; Man, M; Man, MQ; Shi, Y | 1 |
| Bourin, MC; Delescluse, C; Fürstenberger, G; Klein-Szanto, AJ; Marks, F; Prunieras, M; Schweizer, J | 1 |
| Chang, CH; Furue, M; Osada, A; Tamaki, K | 1 |
| Jiang, H; Kato, R; Nishikawa, K; Yamamoto, S | 1 |
| Djuric, SW; Isakson, PC; Rao, TS; Yu, SS | 1 |
| Fischer, SM; Maldve, RE | 1 |
| Jiang, H; Kato, R; Yamamoto, S | 1 |
| Currie, JL; Isakson, PC; Rao, TS; Shaffer, AF | 1 |
| Dandie, GW; Muller, HK; O'Connell, PJ; Ragg, SJ; Woods, GM | 1 |
| Kodari, E; Pavone, A; Reiners, JJ | 3 |
| Conney, AH; Ferraro, T; Georgiadis, C; Ho, CT; Huang, MT; Laskin, JD; Lou, YR; Ma, W; Stauber, K; Wang, ZY | 1 |
| Agarwal, R; Ekker, S; Katiyar, SK; Mukhtar, H; Wood, GS | 1 |
| Goodell, AL; Meyer, SA; Oh, HS; Smart, RC | 1 |
| Albert, RE; French, JE; Maronpot, R; Spalding, J; Tennant, R | 1 |
| Fujisawa, H; Kondo, S; Sauder, DN; Shivji, GM; Wang, B | 1 |
| Reiners, JJ; Singh, KP | 1 |
| Groves, RW; Kupper, TS; Rauschmayr, T | 1 |
| Puigneró, V; Queralt, J | 1 |
| Giner, RM; Máñez, S; Recio, MC; Ríos, JL | 1 |
| Cerdá, M; Cuéllar, MJ; Giner, RM; Hostettmann, K; Just, MJ; Máñez, S; Recio, MC; Ríos, JL | 1 |
| Badger, AM; Breton, J; Chabot-Fletcher, M; Griswold, DE; Martin, LD | 1 |
| Griswold, DE; Newsholme, SJ; Tzimas, MN; Webb, EF | 1 |
| Fisher, GJ; Reynolds, NJ; Voorhees, JJ | 1 |
| Akihisa, T; Kimura, Y; Takido, M; Tamura, T; Yasukawa, K | 1 |
| Hiraiwa, N; Irie, S; Koyama, Y; Kusakabe, M; Kusubata, M; Ohashi, T; Yoshiki, A | 1 |
| Bergman, J; Möller, L; Rozell, BL; Skarin, T; Toftgård, R | 1 |
| Kawabata, K; Koshimizu, K; Murakami, A; Nakamura, Y; Ohigashi, H; Takahashi, D; Tanaka, T | 1 |
| Murakami, A; Nakamura, Y; Ohigashi, H; Ohto, Y; Tanaka, T; Torikai, K | 1 |
| Nakamura, Y; Ohigashi, H; Torikai, K | 1 |
| Ueda, H; Yamazaki, M | 1 |
| Boutwell, RK; Fischer, SM; Gleason, GL; Mufson, RA; Slaga, TJ; Verma, AK | 1 |
| Maté, U; Melchionne, S; Segal, A; Seidman, I; Smith, A; Solomon, JJ; Van Duuren, BL | 1 |
| Maté, U; Segal, A; Van Duuren, BL | 1 |
| Alford, JG; Stanley, PL; Todderud, G; Tramposch, KM | 1 |
| Blumberg, PM; Krausz, KW; Szallasi, Z | 1 |
| Burtin, C; Canu, P; Paupe, J; Ponvert, C | 1 |
| Havens, M; Stanley, PL; Steiner, S; Tramposch, KM | 1 |
| Abidi, TF; Conney, AH; Ferraro, T; Huang, MT; Laskin, JD; Lysz, T | 1 |
| Aizu, E; Jiang, H; Kato, R; Kiyoto, I; Nakadate, T; Wang, JC; Yamamoto, S | 1 |
| Aizu, E; Kato, R; Nakadate, T; Yamamoto, S | 1 |
| Daynes, RA; Huang, K; Im, SY; Samlowski, WE | 1 |
| Dickinson, JL; Halliday, GM; Muller, HK | 1 |
| Halliday, GM; Muller, HK; Odling, KA; Ruby, JC | 1 |
| Czerniecki, B; Gad, SC; Reilly, C; Witz, G | 1 |
| Blackham, A; Griffiths, RJ; Li, S; Wood, BE | 1 |
| Bailly, J; Delescluse, C; Hensby, CN; Vaigot, P | 1 |
| Braisted, J; Dranchak, P; Earnest, TW; Gu, X; Hoon, MA; Inglese, J; Oliphant, E; Solinski, HJ | 1 |
1 review(s) available for tetradecanoylphorbol acetate and Contact Dermatitis
| Article | Year |
|---|---|
Analysis of the mechanism for the development of allergic skin inflammation and the application for its treatment:establishment of a modified allergic dermatitis model in mouse ear lobes by application of 12-O-tetradecanoyl phorbol 13-acetate: putative in
Topics: Animals; Cytokines; Dermatitis, Atopic; Dermatitis, Contact; Disease Models, Animal; Ear; Histamine; Male; Mice; Mice, Inbred BALB C; Picryl Chloride; Tetradecanoylphorbol Acetate; Thymic Stromal Lymphopoietin | 2009 |
91 other study(ies) available for tetradecanoylphorbol acetate and Contact Dermatitis
| Article | Year |
|---|---|
In Vitro and Clinical Evaluation of Cannabigerol (CBG) Produced via Yeast Biosynthesis: A Cannabinoid with a Broad Range of Anti-Inflammatory and Skin Health-Boosting Properties.
Topics: Anti-Inflammatory Agents; Antioxidants; Cannabidiol; Cannabinoids; Cells, Cultured; Dermatitis, Contact; Dermatologic Agents; Female; Gene Expression Regulation; Healthy Volunteers; Humans; Inflammation; Male; Models, Biological; Propionibacteriaceae; Saccharomyces cerevisiae; Skin; Skin Aging; Skin Irritancy Tests; Sodium Dodecyl Sulfate; Tetradecanoylphorbol Acetate; Tissue Array Analysis; Ultraviolet Rays | 2022 |
Aberrant HO-1/NQO1-Reactive Oxygen Species-ERK Signaling Pathway Contributes to Aggravation of TPA-Induced Irritant Contact Dermatitis in Nrf2-Deficient Mice.
Topics: Animals; Dermatitis, Contact; Fibroblasts; Heme Oxygenase-1; Inflammation; Irritants; Mice; Mice, Knockout; NF-E2-Related Factor 2; Reactive Oxygen Species; Signal Transduction; Tetradecanoylphorbol Acetate | 2022 |
N-Methyl-(2S,4R)-trans-4-hydroxy-L-proline isolated Sideroxylon obtusifolium attenuates TPA-induced irritant contact dermatitis in mice.
Topics: Animals; Anti-Inflammatory Agents; Cytokines; Dermatitis; Dermatitis, Contact; Interleukin-6; Irritants; Mice; Sapotaceae; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2023 |
Anti-inflammatory effect of lanoconazole on 12-O-tetradecanoylphorbol-13-acetate- and 2,4,6-trinitrophenyl chloride-induced skin inflammation in mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antifungal Agents; Dermatitis, Contact; Dose-Response Relationship, Drug; Ear, External; Female; Imidazoles; Mice; Mice, Inbred BALB C; Picrates; Tetradecanoylphorbol Acetate; Tinea Pedis | 2020 |
Corticoid-like anti-inflammatory effect of Vochysia bifalcata Warm.: Preclinical evidence of efficacy and safety.
Topics: Adrenal Cortex Hormones; Animals; Anti-Inflammatory Agents; Atrophy; Cell Line; Croton Oil; Dermatitis, Contact; Edema; Female; Humans; Interleukin-6; Mice; Myrtales; Phytotherapy; Plant Extracts; Plant Leaves; Receptors, Glucocorticoid; Skin; Tetradecanoylphorbol Acetate; Treatment Outcome; Tumor Necrosis Factor-alpha | 2020 |
Preclinical study of the topical anti-inflammatory activity of Cyperus rotundus L. extract (Cyperaceae) in models of skin inflammation.
Topics: Adrenal Glands; Animals; Anti-Inflammatory Agents; Arachidonic Acid; Atrophy; Cell Proliferation; Cyperus; Dermatitis, Contact; Edema; Female; Irritants; Keratinocytes; Lymph Nodes; Mice; Phytochemicals; Phytotherapy; Plant Extracts; Rhizome; Skin; Spleen; Tetradecanoylphorbol Acetate; Thymus Gland | 2020 |
Expanding the anti-inflammatory potential of Moringa oleifera: topical effect of seed oil on skin inflammation and hyperproliferation.
Topics: Adrenal Glands; Animals; Anti-Inflammatory Agents; Atrophy; Cell Proliferation; Dermatitis, Contact; Edema; Female; Irritants; Keratinocytes; Lymph Nodes; Mice; Moringa oleifera; Oleic Acid; Plant Oils; Receptors, Glucocorticoid; Seeds; Skin; Spleen; Tetradecanoylphorbol Acetate; Thymus Gland | 2020 |
Anti-inflammatory effect of amygdalin analogs following topical administration on the TPA-induced irritant contact dermatitis model in mice.
Topics: Administration, Topical; Amygdalin; Animals; Anti-Inflammatory Agents; Dermatitis, Contact; Dermatitis, Irritant; Disease Models, Animal; Male; Mice; Mice, Inbred BALB C; Tetradecanoylphorbol Acetate | 2021 |
Wip1 inhibition leads to severe pro-inflammatory phenotype in skin in response to chemical irritation.
Topics: Animals; Dermatitis, Contact; Mice, Inbred C57BL; Mice, Knockout; Protein Phosphatase 2C; Skin; Tetradecanoylphorbol Acetate | 2017 |
Effect of tannic acid on skin barrier function.
Topics: Animals; Dermatitis, Contact; Disease Models, Animal; Epidermis; Fluorescent Dyes; Inflammation; Isoquinolines; Male; Mice; Mice, Inbred ICR; Permeability; Skin; Skin Diseases; Sweat; Tannins; Tetradecanoylphorbol Acetate | 2018 |
Antioxidant and anti-inflammatory activities of the phenolic extracts of Sapium sebiferum (L.) Roxb. leaves.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Catalase; Dermatitis, Contact; Edema; Flavonoids; Glutathione; Male; Mice; Nitrites; Phenols; Phytotherapy; Plant Extracts; Plant Leaves; Sapium; Superoxide Dismutase; Superoxides; Tetradecanoylphorbol Acetate | 2013 |
Structure-dependent inhibitory effects of synthetic cannabinoids against 12-O-tetradecanoylphorbol-13-acetate-induced inflammation and skin tumour promotion in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Cannabinoids; Cocarcinogenesis; Dermatitis, Contact; Female; Mice; Mice, Inbred ICR; Molecular Structure; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 2013 |
Anti-inflammatory effect of a retrovirus-derived immunosuppressive peptide in mouse models.
Topics: Amino Acid Sequence; Animals; Chemokine CXCL2; Dermatitis, Contact; Dermatitis, Irritant; Dimerization; Disease Models, Animal; Gene Expression; Humans; Immunosuppressive Agents; Interleukin-17; Interleukin-6; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Molecular Sequence Data; Oxazolone; Peptides; Retroviridae; Reverse Transcriptase Polymerase Chain Reaction; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2013 |
PEP-1-PON1 protein regulates inflammatory response in raw 264.7 macrophages and ameliorates inflammation in a TPA-induced animal model.
Topics: 4-Butyrolactone; Animals; Anti-Inflammatory Agents; Cell Line; Cell Survival; Cyclooxygenase 2; Cytokines; Dermatitis, Contact; Disease Models, Animal; Lipopolysaccharides; Macrophages; Male; MAP Kinase Signaling System; Mice; Mice, Inbred ICR; NF-kappa B; Oxidative Stress; Reactive Oxygen Species; Tetradecanoylphorbol Acetate | 2014 |
Caffeic acid reduces cutaneous tumor necrosis factor alpha (TNF-α), IL-6 and IL-1β levels and ameliorates skin edema in acute and chronic model of cutaneous inflammation in mice.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Caffeic Acids; Dermatitis, Contact; Dose-Response Relationship, Drug; Edema; Humans; Inflammation; Inflammation Mediators; Interleukin-1beta; Interleukin-6; Keratinocytes; Mice; Mice, Inbred BALB C; Neutrophils; NF-kappa B; Peroxidase; Plant Extracts; RNA, Messenger; Skin; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2014 |
Topical cannabinoid receptor 1 agonist attenuates the cutaneous inflammatory responses in oxazolone-induced atopic dermatitis model.
Topics: Acute Disease; Administration, Cutaneous; Animals; Cannabinoid Receptor Agonists; Chronic Disease; Dermatitis, Atopic; Dermatitis, Contact; Disease Models, Animal; Fatty Acids, Unsaturated; Female; Mice, Inbred BALB C; Oxazolone; Permeability; Propanolamines; Receptor, Cannabinoid, CB1; Skin; Skin Physiological Phenomena; Tetradecanoylphorbol Acetate; Water Loss, Insensible | 2015 |
Hematopoietic plakophilin-3 regulates acute tissue-specific and systemic inflammation in mice.
Topics: Animals; Colitis; Dermatitis, Contact; Dextran Sulfate; Gene Expression Regulation; Inflammation; Lipopolysaccharides; Mice; Mice, Knockout; Neutrophils; Plakophilins; Tetradecanoylphorbol Acetate | 2015 |
Inhibitory Effects of 4'-Demethylnobiletin, a Metabolite of Nobiletin, on 12-O-Tetradecanoylphorbol-13-acetate (TPA)-Induced Inflammation in Mouse Ears.
Topics: Animals; Anti-Inflammatory Agents; Cyclooxygenase 2; Cytokines; Dermatitis; Dermatitis, Contact; Ear; Edema; Flavones; Male; Matrix Metalloproteinase 9; Mice; Nitric Oxide Synthase Type II; Phosphatidylinositol 3-Kinases; Phosphorylation; Phytotherapy; Skin; Tetradecanoylphorbol Acetate | 2015 |
Pre-administration of PepFect6-microRNA-146a nanocomplexes inhibits inflammatory responses in keratinocytes and in a mouse model of irritant contact dermatitis.
Topics: Animals; Anti-Inflammatory Agents; Cell Survival; Cells, Cultured; Cytokines; Dermatitis, Contact; Disease Models, Animal; Humans; Irritants; Keratinocytes; Lipopeptides; Mice, Inbred C57BL; MicroRNAs; Microscopy, Electron, Transmission; Nanoparticles; Quinolines; Tetradecanoylphorbol Acetate | 2016 |
Anti-proliferative and anti-inflammatory effects of 3β,6β,16β-Trihydroxylup-20(29)-ene on cutaneous inflammation.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Cell Line; Cell Proliferation; Chronic Disease; Dermatitis, Contact; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Female; Hormone Antagonists; Humans; Keratinocytes; Mice; Mifepristone; Proliferating Cell Nuclear Antigen; Psoriasis; Receptors, Glucocorticoid; Skin; Tetradecanoylphorbol Acetate; Time Factors; Triterpenes | 2017 |
Topically applied diterpenoids from Egletes viscosa (Asteraceae) attenuate the dermal inflammation in mouse ear induced by tetradecanoylphorbol 13-acetate- and oxazolone.
Topics: Acute Disease; Administration, Topical; Animals; Anti-Inflammatory Agents; Asteraceae; Chronic Disease; Dermatitis, Contact; Diterpenes; Ear, External; Fatty Acids, Unsaturated; Flowers; Furans; Interferon-gamma; Lactones; Male; Mice; Oxazolone; Peroxidase; Skin; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2008 |
Inhibition of atopic dermatitis-like skin lesions by topical application of a novel ceramide derivative, K6PC-9p, in NC/Nga mice.
Topics: Administration, Topical; Animals; Antigens, Dermatophagoides; Cell Movement; Cell Survival; Ceramides; Dermatitis, Atopic; Dermatitis, Contact; Disease Models, Animal; Ear, External; Female; Fibroblasts; Gene Expression; Humans; Hydrocortisone; Interleukin-4; Keratinocytes; Macrophage Activation; Mast Cells; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Reverse Transcriptase Polymerase Chain Reaction; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2008 |
Inhibition of skin inflammation and atopic dermatitis by topical application of a novel ceramide derivative, K112PC-5, in mice.
Topics: Administration, Topical; Allergens; Animals; Cell Proliferation; Ceramides; Dermatitis, Atopic; Dermatitis, Contact; Dermatologic Agents; Ear, External; Female; Interleukin-1; Interleukin-4; Macrophages; Mice; Mice, Inbred BALB C; Nitric Oxide; Pyroglyphidae; Skin; T-Lymphocytes; Tetradecanoylphorbol Acetate | 2008 |
Chronic inflammation that facilitates tumor progression creates local immune suppression by inducing indoleamine 2,3 dioxygenase.
Topics: Animals; Dendritic Cells; Dermatitis, Contact; Disease Progression; Immune Tolerance; Indoleamine-Pyrrole 2,3,-Dioxygenase; Lymph Nodes; Mice; Mice, Inbred C57BL; Models, Animal; Papilloma; Signal Transduction; Skin Neoplasms; T-Lymphocytes; Tetradecanoylphorbol Acetate | 2008 |
Fullerene nanomaterials inhibit phorbol myristate acetate-induced inflammation.
Topics: Animals; Dermatitis, Contact; Ear Auricle; Edema; Fullerenes; Inflammation; Injections, Subcutaneous; Male; Mice; Mice, Inbred Strains; Molecular Structure; Nanostructures; Tetradecanoylphorbol Acetate | 2009 |
RIP4 regulates epidermal differentiation and cutaneous inflammation.
Topics: 14-3-3 Proteins; 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Differentiation; Dermatitis, Contact; Epidermis; Female; Humans; I-kappa B Kinase; Keratin-14; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Pregnancy; Promoter Regions, Genetic; Protein Kinase C; Protein Kinases; Protein Serine-Threonine Kinases; Receptors, Tumor Necrosis Factor, Type I; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2010 |
The role of mitogen-activated protein kinase-activated protein kinase 2 in the p38/TNF-alpha pathway of systemic and cutaneous inflammation.
Topics: Animals; Dermatitis, Contact; Dinitrofluorobenzene; Female; Granulocytes; Homozygote; Inflammation; Intracellular Signaling Peptides and Proteins; Mice; Mice, Inbred C57BL; p38 Mitogen-Activated Protein Kinases; Protein Serine-Threonine Kinases; Receptors, Antigen, T-Cell; Skin; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2010 |
Topical anti-inflammatory potential of Physalin E from Physalis angulata on experimental dermatitis in mice.
Topics: Animals; Anti-Inflammatory Agents; Dermatitis, Contact; Immunohistochemistry; Male; Mice; Oxazolone; Physalis; Secosteroids; Tetradecanoylphorbol Acetate | 2010 |
Inhibitory effect of magnolol on TPA-induced skin inflammation and tumor promotion in mice.
Topics: Animals; Base Sequence; Biphenyl Compounds; Carcinogens; Dermatitis, Contact; DNA Primers; Electrophoretic Mobility Shift Assay; Lignans; Mice; Neoplasms, Experimental; Reverse Transcriptase Polymerase Chain Reaction; Tetradecanoylphorbol Acetate | 2010 |
Anti-inflammatory effects of Glehnia littoralis extract in acute and chronic cutaneous inflammation.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Apiaceae; Capillary Permeability; Chromatography, High Pressure Liquid; Dermatitis, Contact; Ear; Edema; Interleukin-1beta; Male; Mice; Mice, Inbred C57BL; Peroxidase; Plant Extracts; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2010 |
Anti-inflammatory effect of crude extract and isolated compounds from Baccharis illinita DC in acute skin inflammation.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Arachidonic Acid; Baccharis; Capsaicin; Dermatitis, Contact; Disease Models, Animal; Diterpenes; Dose-Response Relationship, Drug; Ear; Edema; Male; Mice; Neutrophil Infiltration; Oleanolic Acid; Plant Leaves; Plant Preparations; Stigmasterol; Tetradecanoylphorbol Acetate | 2010 |
Topical azithromycin and clarithromycin inhibit acute and chronic skin inflammation in sensitized mice, with apparent selectivity for Th2-mediated processes in delayed-type hypersensitivity.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Azithromycin; Cell Degranulation; Clarithromycin; Dermatitis, Contact; Dexamethasone; Ear; Hypersensitivity, Delayed; Immunoglobulin E; Interferon-gamma; Interleukin-1beta; Interleukin-4; Mast Cells; Mice; Oxazolone; Skin; Tetradecanoylphorbol Acetate; Th2 Cells; Tumor Necrosis Factor-alpha | 2012 |
Attenuation of experimental TPA-induced dermatitis by acetylenic acetogenins is associated with inhibition of PLA₂ activity.
Topics: Acetogenins; Acetylene; Animals; Anti-Inflammatory Agents; Cell Line; Dermatitis, Contact; Enzyme Inhibitors; Humans; Male; Mice; Phospholipase A2 Inhibitors; Phospholipases A2; Tetradecanoylphorbol Acetate | 2011 |
Topical application of marine briarane-type diterpenes effectively inhibits 12-O-tetradecanoylphorbol-13-acetate-induced inflammation and dermatitis in murine skin.
Topics: Administration, Cutaneous; Animals; Cyclooxygenase 2; Dermatitis, Contact; Diterpenes; Edema; Inflammation; Interleukin-6; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase Type II; Skin; Tetradecanoylphorbol Acetate | 2011 |
Inhibition of CXCR2 profoundly suppresses inflammation-driven and spontaneous tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenoma; Animals; Animals, Inbred Strains; Azoxymethane; Cell Transformation, Neoplastic; Chemokines, CXC; Colitis; Colonic Neoplasms; Dermatitis, Contact; Dextran Sulfate; Gene Expression; Mice; Mice, 129 Strain; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Neutrophils; Papilloma; Peroxidase; Precancerous Conditions; Receptors, Interleukin-8B; Skin Neoplasms; Statistics, Nonparametric; Tetradecanoylphorbol Acetate; Tumor Burden | 2012 |
Combretum leprosum Mart. (Combretaceae): potential as an antiproliferative and anti-inflammatory agent.
Topics: Acetylglucosaminidase; Animals; Anti-Inflammatory Agents; Arachidonic Acid; Cell Line; Cell Proliferation; Combretum; Croton Oil; Dermatitis, Contact; Disease Models, Animal; Dose-Response Relationship, Drug; Ear; Edema; Ethanol; Female; Flowers; Interleukin-6; Mice; Peroxidase; Phytotherapy; Plant Extracts; Proliferating Cell Nuclear Antigen; Skin; Tetradecanoylphorbol Acetate | 2013 |
Overexpression of skin protein kinase C-alpha in anagen hair follicles during induced growth of mouse hair.
Topics: Administration, Topical; Animals; Dermatitis, Contact; Female; Hair; Hair Follicle; Hair Removal; Irritants; Mice; Mice, Inbred C57BL; Protein Kinase C; Protein Kinase C-alpha; Tetradecanoylphorbol Acetate | 2003 |
Involvement of tumor necrosis factor (TNF)-alpha in phorbol ester 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced skin edema in mice.
Topics: Animals; Dermatitis, Contact; Dinoprostone; Disease Models, Animal; Etanercept; Immunoglobulin G; Mice; Mice, Inbred BALB C; Receptors, Tumor Necrosis Factor; Skin; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2006 |
Inhibition of the TPA-induced cutaneous inflammation and hyperplasia by EC-SOD.
Topics: Animals; Dermatitis, Contact; Hyperplasia; Interleukin-1; Mice; Mice, Transgenic; Oxidative Stress; Superoxide Dismutase; Tetradecanoylphorbol Acetate | 2006 |
Mechanisms underlying the inhibitory actions of the pentacyclic triterpene alpha-amyrin in the mouse skin inflammation induced by phorbol ester 12-O-tetradecanoylphorbol-13-acetate.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Cyclooxygenase 1; Cyclooxygenase 2; Dermatitis, Contact; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Induction; Extracellular Signal-Regulated MAP Kinases; I-kappa B Proteins; Male; MAP Kinase Signaling System; Membrane Proteins; Mice; NF-kappa B; Oleanolic Acid; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C-alpha; Skin; Tetradecanoylphorbol Acetate; Time Factors; Transcription Factor RelA | 2007 |
Anti-inflammatory activity of sertaconazole nitrate is mediated via activation of a p38-COX-2-PGE2 pathway.
Topics: Acne Vulgaris; Animals; Anti-Inflammatory Agents; Antifungal Agents; Biopsy; Carcinogens; Cell Line; Cyclooxygenase 2; Cytokines; Dermatitis, Contact; Dinoprostone; Enzyme Activation; Gram-Positive Bacterial Infections; Humans; Imidazoles; Irritants; Keratinocytes; Leukocytes, Mononuclear; Mice; p38 Mitogen-Activated Protein Kinases; Propionibacterium acnes; RNA, Small Interfering; Signal Transduction; Tetradecanoylphorbol Acetate; Thiophenes | 2008 |
Crucial role of phospholipase C epsilon in skin inflammation induced by tumor-promoting phorbol ester.
Topics: Animals; Carcinogens; Dermatitis, Contact; Fibroblasts; Interleukin-1; Keratinocytes; Mice; Mice, Mutant Strains; Phosphoinositide Phospholipase C; rap1 GTP-Binding Proteins; ras Guanine Nucleotide Exchange Factors; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2008 |
Chinese herbal medicine (Tuhuai extract) exhibits topical anti-proliferative and anti-inflammatory activity in murine disease models.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Cell Proliferation; Dermatitis, Allergic Contact; Dermatitis, Contact; Disease Models, Animal; Drugs, Chinese Herbal; Fabaceae; Female; Glycyrrhiza; Humans; Hyperplasia; Male; Mice; Mice, Hairless; Oxazolone; Phytotherapy; Psoriasis; Skin; Smilax; Tetradecanoylphorbol Acetate | 2008 |
Effect of phorbol esters on guniea pig skin in vivo.
Topics: Animals; Cell Division; Dermatitis, Contact; DNA; Epidermis; Female; Guinea Pigs; Indomethacin; Ornithine Decarboxylase; Phorbols; Prostaglandins; Skin; Tetradecanoylphorbol Acetate | 1982 |
Immunosuppressive effects of azelastine hydrochloride on contact hypersensitivity and T-cell proliferative response: a comparative study with FK-506.
Topics: Administration, Topical; Animals; Bronchodilator Agents; Cell Division; Cells, Cultured; Dermatitis, Contact; DNA; Immunosuppressive Agents; In Vitro Techniques; Interleukin-2; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Phthalazines; Receptors, Interleukin-2; T-Lymphocytes; Tacrolimus; Tetradecanoylphorbol Acetate; Thymidine; Time Factors; Tritium | 1994 |
Anti-tumor-promoting action of FK506, a potent immunosuppressive agent.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Dermatitis, Contact; Enzyme Induction; Female; Mice; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Papilloma; Phosphorylation; Skin Neoplasms; Tacrolimus; Tetradecanoylphorbol Acetate | 1993 |
Phorbol ester-induced dermal inflammation in mice: evaluation of inhibitors of 5-lipoxygenase and antagonists of leukotriene B4 receptor.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Benzamides; Benzopyrans; Dermatitis, Contact; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Indomethacin; Leukotriene B4; Lipoxygenase Inhibitors; Male; Mice; Mice, Inbred BALB C; Receptors, Leukotriene B4; Tetradecanoylphorbol Acetate | 1994 |
Tumor-promoting activity of 2,4-dinitrofluorobenzene.
Topics: Animals; Carcinogens; Dermatitis, Contact; Dinitrofluorobenzene; Dose-Response Relationship, Drug; Enzyme Induction; Female; Gene Expression Regulation, Neoplastic; Genes, fos; Genes, jun; Hyperplasia; Mice; Mice, Inbred SENCAR; Ornithine Decarboxylase; Papilloma; Protein Kinase C; RNA, Small Nuclear; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1995 |
Anti-inflammatory action of orally active 5-lipoxygenase inhibitor TMK688.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cells, Cultured; Cyclooxygenase Inhibitors; Dermatitis, Contact; Dinoprostone; Dose-Response Relationship, Drug; Female; Leukotriene B4; Lipoxygenase Inhibitors; Mice; Piperidines; Tetradecanoylphorbol Acetate | 1994 |
Comparative evaluation of arachidonic acid (AA)- and tetradecanoylphorbol acetate (TPA)-induced dermal inflammation.
Topics: Acetylglucosaminidase; Animals; Arachidonic Acid; Capillary Permeability; Cyclooxygenase Inhibitors; Dermatitis, Contact; Disease Models, Animal; Edema; Eicosanoids; Female; Leukotriene Antagonists; Lipoxygenase Inhibitors; Lymphocytes; Male; Mast Cells; Mice; Mice, Inbred BALB C; Neutrophils; Peroxidase; Tetradecanoylphorbol Acetate | 1993 |
Langerhans cell migration patterns from sheep skin following topical application of carcinogens.
Topics: Acetone; Animals; Benzopyrenes; Carcinogens; Cell Movement; Dermatitis, Contact; Kinetics; Langerhans Cells; Mice; Mice, Inbred BALB C; Sheep; Skin; Tetradecanoylphorbol Acetate; Urethane | 1994 |
Differential modulation of contact hypersensitivity and delayed hypersensitivity reactions by topical application of 12-O-tetradecanoylphorbol-13-acetate.
Topics: Administration, Topical; Animals; Cocarcinogenesis; Dermatitis, Contact; Female; Hypersensitivity, Delayed; Immunosuppressive Agents; Immunotherapy, Adoptive; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Skin Neoplasms; T-Lymphocytes, Regulatory; Tetradecanoylphorbol Acetate | 1993 |
Inhibition of skin tumorigenesis by rosemary and its constituents carnosol and ursolic acid.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Abietanes; Animals; Anticarcinogenic Agents; Antioxidants; Arachidonic Acid; Benzo(a)pyrene; Dermatitis, Contact; DNA; Drug Interactions; Enzyme Induction; Epidermis; Female; Hyperplasia; Magnoliopsida; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; Phenanthrenes; Plant Extracts; Skin; Skin Neoplasms; Spices; Tetradecanoylphorbol Acetate; Triterpenes; Tritium; Ursolic Acid | 1994 |
Protection against 12-O-tetradecanoylphorbol-13-acetate-caused inflammation in SENCAR mouse ear skin by polyphenolic fraction isolated from green tea.
Topics: Animals; Anticarcinogenic Agents; Dermatitis, Contact; Ear; Edema; Female; Flavonoids; Hyperplasia; Mice; Neutrophils; Phenols; Polymers; Polyphenols; Skin; Tea; Tetradecanoylphorbol Acetate | 1993 |
Epidermal protein kinase C-beta 2 is highly sensitive to downregulation and is exclusively expressed in Langerhans cells: downregulation is associated with attenuated contact hypersensitivity.
Topics: Animals; Dermatitis, Contact; Diglycerides; Down-Regulation; Epidermis; Female; Immunohistochemistry; Isoenzymes; Langerhans Cells; Mice; Mice, Inbred Strains; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-alpha; Tetradecanoylphorbol Acetate | 1996 |
Mechanism of skin tumorigenesis by contact sensitizers: the effect of the corticosteroid fluocinolone acetonide on inflammation and tumor induction by 2,4 dinitro-1-fluorobenzene in the skin of the TG.AC (v-Ha-ras) mouse.
Topics: Animals; Dermatitis, Contact; Dinitrofluorobenzene; Dose-Response Relationship, Drug; Female; Fluocinolone Acetonide; Genes, ras; Glucocorticoids; Mice; Mice, Transgenic; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1996 |
The role of CD4 molecules in the induction phase of contact hypersensitivity cytokine profiles in the skin and lymph nodes.
Topics: Animals; CD4 Antigens; Cytokines; Dermatitis, Contact; Gene Expression; Interferon-gamma; Interleukin-1; Interleukin-10; Interleukin-2; Interleukin-4; Lymph Nodes; Mice; Mice, Inbred C57BL; Mice, Knockout; Polymerase Chain Reaction; RNA, Messenger; Skin; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1996 |
Susceptibility of 129/SvEv mice in two-stage carcinogenesis protocols to 12-O-tetradecanoylphorbol-13-acetate promotion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Cutaneous; Animals; Biomarkers; Carcinogens; Carcinoma, Squamous Cell; Cocarcinogenesis; Dermatitis, Contact; Disease Susceptibility; Dose-Response Relationship, Drug; Drug Synergism; Epidermis; Hyperplasia; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Mutant Strains; Neutrophils; Papilloma; Peroxidase; Skin Neoplasms; Species Specificity; Tetradecanoylphorbol Acetate | 1997 |
Keratinocyte expression of the type 2 interleukin 1 receptor mediates local and specific inhibition of interleukin 1-mediated inflammation.
Topics: Animals; Animals, Genetically Modified; Cell Adhesion; Cells, Cultured; Dermatitis, Contact; Epidermal Cells; Epidermis; Granulocyte-Macrophage Colony-Stimulating Factor; Immunohistochemistry; Inflammation; Interleukin-1; Keratinocytes; Mice; Receptors, Interleukin-1; Receptors, Interleukin-1 Type II; Recombinant Proteins; Tetradecanoylphorbol Acetate | 1997 |
Effect of topically applied cyclosporin A on arachidonic acid (AA)- and tetradecanoylphorbol acetate (TPA)-induced dermal inflammation in mouse ear.
Topics: Acetylglucosaminidase; Administration, Topical; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Capillary Permeability; Cyclooxygenase Inhibitors; Cyclosporine; Dermatitis, Contact; Dexamethasone; Eicosanoids; Glucocorticoids; Immunosuppressive Agents; Indomethacin; Lipoxygenase Inhibitors; Male; Mice; Peroxidase; Pyrazoles; Tetradecanoylphorbol Acetate | 1997 |
Effect of selected triterpenoids on chronic dermal inflammation.
Topics: Animals; Anti-Inflammatory Agents; Betulinic Acid; Dermatitis, Contact; Dexamethasone; Drug Evaluation, Preclinical; Female; Mice; Oleanolic Acid; Pentacyclic Triterpenes; Tetradecanoylphorbol Acetate; Triterpenes; Ursolic Acid | 1997 |
Zanhasaponins A and B, antiphospholipase A2 saponins from an antiinflammatory extract of Zanha africana root bark.
Topics: Adjuvants, Immunologic; Animals; Anti-Inflammatory Agents; Dermatitis, Contact; Edema; Enzyme Inhibitors; Female; Mice; Oxazolone; Peroxidase; Phospholipases A; Phospholipases A2; Saponins; Skin; Tetradecanoylphorbol Acetate; Triterpenes | 1997 |
Evaluation of the cutaneous anti-inflammatory activity of azaspiranes.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Cell Line; Cyclooxygenase 1; Dermatitis, Contact; Dinoprostone; Ear; Edema; Humans; Immunosuppressive Agents; Isoenzymes; Leukotriene B4; Male; Membrane Proteins; Mice; Mice, Inbred BALB C; Monocytes; NF-kappa B; Peroxidase; Piperidines; Prostaglandin-Endoperoxide Synthases; Spiro Compounds; Tetradecanoylphorbol Acetate | 1998 |
Intralesional cytokines in chronic oxazolone-induced contact sensitivity suggest roles for tumor necrosis factor alpha and interleukin-4.
Topics: Animals; Chronic Disease; Dermatitis, Contact; Immunoglobulin E; Interferon-gamma; Interleukin-4; Male; Mast Cells; Mice; Mice, Inbred BALB C; Oxazolone; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1998 |
Cyclosporin A inhibits 12-O-tetradecanoyl-phorbol-13-acetate-induced cutaneous inflammation in severe combined immunodeficient mice that lack functional lymphocytes.
Topics: Animals; Cyclosporine; Dermatitis, Contact; Epidermis; Immune Tolerance; Immunosuppressive Agents; Lymphocytes; Mice; Mice, SCID; Tetradecanoylphorbol Acetate | 1998 |
Inhibitory effect of cycloartenol ferulate, a component of rice bran, on tumor promotion in two-stage carcinogenesis in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogens; Cocarcinogenesis; Dermatitis, Contact; Female; Hypolipidemic Agents; Mice; Mice, Inbred ICR; Oryza; Phenylpropionates; Phytosterols; Plant Extracts; Skin; Skin Neoplasms; Sterols; Tetradecanoylphorbol Acetate; Triterpenes | 1998 |
Effect of tenascin-C deficiency on chemically induced dermatitis in the mouse.
Topics: Animals; Dermatitis, Contact; Dinitrofluorobenzene; Ear; Genotype; Immunohistochemistry; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Knockout; Skin; Tenascin; Tetradecanoylphorbol Acetate | 1998 |
Protection against 12-O-tetradecanoylphorbol-13-acetate induced skin-hyperplasia and tumor promotion, in a two-stage carcinogenesis mouse model, by the 2,3-dimethyl-6(2-dimethylaminoethyl)-6H-indolo-[2,3-b]quinoxaline analogue of ellipticine.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Benzoyl Peroxide; Carcinogens; Dermatitis, Contact; Female; Hyperplasia; Indoles; Mice; Mice, Inbred SENCAR; Precancerous Conditions; Quinoxalines; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1999 |
Suppression by citrus auraptene of phorbol ester-and endotoxin-induced inflammatory responses: role of attenuation of leukocyte activation.
Topics: Animals; Anticarcinogenic Agents; Carcinogens; Cell Division; Coumarins; Cyclooxygenase 2; Dermatitis, Contact; Edema; Female; Hydrogen Peroxide; Isoenzymes; Leukocytes; Lipopolysaccharides; Macrophage Activation; Macrophages; Mice; Mice, Inbred ICR; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Prostaglandin-Endoperoxide Synthases; Skin; Skin Neoplasms; Superoxides; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Umbelliferones | 2000 |
A simple phenolic antioxidant protocatechuic acid enhances tumor promotion and oxidative stress in female ICR mouse skin: dose-and timing-dependent enhancement and involvement of bioactivation by tyrosinase.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antioxidants; Biotransformation; Carcinogens; Dermatitis, Contact; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Synergism; Female; Glutathione; Glutathione Peroxidase; Glutathione Transferase; Hydrogen Peroxide; Hydroxybenzoates; Mice; Mice, Inbred ICR; Monophenol Monooxygenase; Oxidative Stress; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2000 |
A catechol antioxidant protocatechuic acid potentiates inflammatory leukocyte-derived oxidative stress in mouse skin via a tyrosinase bioactivation pathway.
Topics: Animals; Antioxidants; Cell Survival; Dermatitis, Contact; Drug Synergism; Female; HL-60 Cells; Humans; Hydroxybenzoates; Inflammation; Leukocytes; Mice; Mice, Inbred ICR; Models, Biological; Monophenol Monooxygenase; Oxidative Stress; Skin; Tetradecanoylphorbol Acetate | 2001 |
Anti-inflammatory and anti-allergic actions by oral administration of a perilla leaf extract in mice.
Topics: Administration, Oral; Animals; Anti-Allergic Agents; Anti-Inflammatory Agents; Arachidonic Acid; Dermatitis, Contact; Disease Models, Animal; Edema; Magnoliopsida; Male; Mice; Mice, Inbred ICR; Oxazolone; Plant Extracts; Tetradecanoylphorbol Acetate | 2001 |
Effects of 12-O-tetradecanoylphorbol-13-acetate and mezerein on epidermal ornithine decarboxylase activity, isoproterenol-stimulated levels of cyclic adenosine 3':5'-monophosphate, and induction of mouse skin tumors in vivo.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Division; Cyclic AMP; Dermatitis, Contact; Diterpenes; Female; Isoproterenol; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Papilloma; Phorbol Esters; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1979 |
Tumor-promoting activity of 2,3-dihydrophorbol myristate acetate and phorbolol myristate acetate in mouse skin.
Topics: Animals; Dermatitis, Contact; Female; Mice; Mice, Inbred ICR; Neoplasms, Experimental; Papilloma; Phorbols; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1978 |
The identification of phorbolol myristate acetate as a new metabolite of phorbol myristate acetate in mouse skin.
Topics: Animals; Dermatitis, Contact; Female; Mice; Mice, Inbred ICR; Mitosis; Phorbols; Skin; Stimulation, Chemical; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Thymidine | 1975 |
Temporal infiltration of leukocyte subsets into mouse skin inflamed with phorbol ester.
Topics: Animals; Dermatitis, Contact; Female; Hydrocortisone; Immunohistochemistry; Leukocytes; Lymphocytes; Macrophages; Mice; Neutrophils; Peroxidase; Skin; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1992 |
Non-promoting 12-deoxyphorbol 13-esters as potent inhibitors of phorbol 12-myristate 13-acetate-induced acute and chronic biological responses in CD-1 mouse skin.
Topics: Animals; Dermatitis, Contact; Drug Antagonism; Enzyme Induction; Hyperplasia; Keratins; Mice; Ornithine Decarboxylase; Peroxidase; Phorbol Esters; Skin; Tetradecanoylphorbol Acetate | 1992 |
Modifications in tissue histamine levels in mice treated with chronic epicutaneous application of phorbol-12-myristate-13-acetate.
Topics: Administration, Cutaneous; Animals; Dermatitis, Contact; Female; Gastric Mucosa; Histamine; Mice; Mice, Inbred C57BL; Muscles; Skin; Stomach; Tetradecanoylphorbol Acetate; Time Factors | 1992 |
Mouse skin inflammation induced by multiple topical applications of 12-O-tetradecanoylphorbol-13-acetate.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Dermatitis, Contact; Disease Models, Animal; Ear, External; Edema; Female; Hyperplasia; Mice; Mice, Inbred Strains; Neutrophils; Skin; Tetradecanoylphorbol Acetate; Time Factors | 1991 |
Induction of suppressor T cells and inhibition of contact hypersensitivity in mice by 12-O-tetradecanoylphorbol-13-acetate and its analogs.
Topics: Administration, Cutaneous; Animals; Capillary Permeability; Dermatitis, Contact; Dinitrofluorobenzene; Female; Immunotherapy, Adoptive; Kinetics; Langerhans Cells; Mice; T-Lymphocytes, Regulatory; Terpenes; Tetradecanoylphorbol Acetate | 1991 |
Inhibitory effects of curcumin on in vitro lipoxygenase and cyclooxygenase activities in mouse epidermis.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Caffeic Acids; Chlorogenic Acid; Coumaric Acids; Curcumin; Dermatitis, Contact; Female; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Lipoxygenase; Mice; Peroxidases; Prostaglandin-Endoperoxide Synthases; Tetradecanoylphorbol Acetate | 1991 |
The potent anti-tumor-promoting agent isoliquiritigenin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Aldehyde Reductase; Animals; Arachidonate 12-Lipoxygenase; Arachidonate 5-Lipoxygenase; Benz(a)Anthracenes; Blood Platelets; Chalcone; Chalcones; Dermatitis, Contact; Enzyme Induction; Female; Mice; Mice, Inbred Strains; Neutrophils; Ornithine Decarboxylase; Phospholipases A; Phospholipases A2; Prostaglandins; Skin; Skin Neoplasms; Sonication; Tetradecanoylphorbol Acetate | 1991 |
Local- and systemic-mediated suppression of contact hypersensitivity in mice by several structurally unrelated classes of tumor promoters.
Topics: Administration, Topical; Alkanes; Alkynes; Animals; Anthralin; Antibody Formation; Benzoyl Peroxide; Carcinogens; Dermatitis, Contact; Dinitrofluorobenzene; Female; Langerhans Cells; Mice; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1991 |
Anti-tumor promoting action of phthalic acid mono-n-butyl ester cupric salt, a biomimetic superoxide dismutase.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Antineoplastic Agents; Benz(a)Anthracenes; Cells, Cultured; Dermatitis, Contact; Dibutyl Phthalate; Ear Diseases; Edema; Enzyme Induction; Epidermal Cells; Epidermis; Female; Mice; Ornithine Decarboxylase; Papilloma; Phthalic Acids; Skin Neoplasms; Superoxide Dismutase; Tetradecanoylphorbol Acetate | 1990 |
Molecular mechanisms of lymphocyte extravasation. III. The loss of lymphocyte extravasation potential induced by pertussis toxin is not mediated via the activation of protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Antigens, Surface; Cell Adhesion; Cell Adhesion Molecules; Cell Movement; Dermatitis, Contact; Dinitrofluorobenzene; Endothelium, Lymphatic; Enzyme Activation; Immunization, Passive; Intestines; Isoquinolines; Lymph Nodes; Lymphocytes; Mice; Mice, Inbred C3H; Pertussis Toxin; Piperazines; Protein Kinase C; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1989 |
Retinoic acid protects Langerhans' cells from the effects of the tumour promotor 12-O-tetradecanoylphorbol 13-acetate.
Topics: Animals; Cell Count; Dermatitis, Contact; Langerhans Cells; Male; Mice; Mice, Inbred BALB C; Tetradecanoylphorbol Acetate; Tretinoin | 1989 |
Suppressor cell activation and enhanced skin allograft survival after tumor promotor but not initiator induced depletion of cutaneous Langerhans cells.
Topics: Animals; Dermatitis, Contact; Graft Survival; Langerhans Cells; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Skin; Skin Transplantation; T-Lymphocytes, Regulatory; Tetradecanoylphorbol Acetate; Urethane | 1988 |
The development of contact hypersensitivity in mouse skin is suppressed by tumor promoters.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Benzoyl Peroxide; Carcinogens; Dermatitis, Contact; Dinitrochlorobenzene; Diterpenes; Female; Immunosuppressive Agents; Mice; Terpenes; Tetradecanoylphorbol Acetate | 1988 |
Pharmacological modification of 12-0-tetradecanoylphorbol-13-acetate induced inflammation and epidermal cell proliferation in mouse skin.
Topics: Animals; Colchicine; Cyclooxygenase Inhibitors; Dermatitis, Contact; Dinoprostone; Ear; Edema; Epidermis; Female; Lipoxygenase Inhibitors; Mice; Neutrophils; Prednisolone; Protein Biosynthesis; Tetradecanoylphorbol Acetate | 1988 |
Effects of antiinflammatory agents on edema and DNA synthesis induced by 12-O-tetradecanoylphorbol-13-acetate in the guinea pig.
Topics: Animals; Anti-Inflammatory Agents; Dermatitis, Contact; DNA; Edema; Guinea Pigs; Hyperplasia; Male; Tetradecanoylphorbol Acetate | 1987 |
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, Spinal; Humans; Mice, Inbred C57BL; Mice, Knockout; Neurons; Pruritus; Receptors, Atrial Natriuretic Factor; Reproducibility of Results; Signal Transduction; Small Molecule Libraries | 2019 |