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tetradecanoylphorbol acetate and Cell Transformation, Neoplastic

tetradecanoylphorbol acetate has been researched along with Cell Transformation, Neoplastic in 934 studies

Research

Studies (934)

TimeframeStudies, this research(%)All Research%
pre-1990428 (45.82)18.7374
1990's267 (28.59)18.2507
2000's144 (15.42)29.6817
2010's88 (9.42)24.3611
2020's7 (0.75)2.80

Authors

AuthorsStudies
Chou, P; Kong, AN; Kuo, HC; Li, S; Phadnis, A; Sargsyan, D; Sarwar, MS; Su, S; Su, X; Wang, L; Wang, Y; Wu, R1
Abe, K; Kamei, A; Ohmori, K; Watanabe, Y1
Kong, AT; Kuo, HD; Sargsyan, D; Sarwar, MS; Suh, N; Wang, C; Wu, R; Zheng, M1
Akira, S; Morisaka, H; Sano, S; Takaishi, M1
Gaté, L; Guichard, Y; Savoy, C1
Hudlikar, RR; Kong, AN; Sargsyan, D; Su, S; Wu, R; Zheng, M1
Kreft, M; Krotenberg Garcia, A; Ramovs, V; Sonnenberg, A1
Chen, Y; Qiao, Y; Sun, F; Wang, J; Wu, Q; Zhang, X; Zhao, Y; Zhu, G1
Baek, M; DiGiovanni, J; Jang, IS; Kim, DJ; Kim, M; Lee, H; Morales, LD; Slaga, TJ1
Callejas-Valera, JL; Cimas, FJ; Fernandez-Aroca, DM; Garcia-Gil, E; García-Olmo, DC; Gutkind, JS; Hernández-Losa, J; Marcos, P; Melgar-Rojas, P; Ortega-Muelas, M; Pascual-Serra, R; Ramón Y Cajal, S; Roche, O; Ruiz-Hidalgo, MJ; Sanchez-Prieto, R1
Jeong, WS; Kong, AN; Truong, VL1
Franco, R; Hernández-Franco, P; Rojas, E; Silva, M; Valverde, M1
Cao, M; Fang, M; Guo, Y; Kong, AN; Su, ZY; Wu, R; Yang, I; Yang, Y1
Balmain, A; Del Rosario, R; Harris, S; Kandyba, E; Reeves, MQ1
Balaiya, V; Johnson, LK; Koster, MI; Lakshmanachetty, S1
Li, Y; Liu, X; Lu, Y; Pei, B; Shen, W; Sun, D; Wang, X; Xiu, L; Xu, J; Yue, X; Zhang, X1
Hall, JR; House, JS; Jima, DD; Messenger, ZJ; Smart, RC; Tam, HW; Tokarz, DA1
Asfaha, S; Boland, K; Gordon, D; Jin, G; Johnson, K; Lad, S; Londono, D; Morris, RJ; Park, H; Patterson, KS; Readio, N; Singh, A; Trempus, C; Wang, TC; Yang, X1
Gubareva, EA; Maidin, MA; Panchenko, AV; Tyndyk, ML; Vinogradova, LA1
Kong, AN; Li, S; Raskin, I; Sargsyan, D; Su, S; Wang, C; Wu, R; Yin, R; Zheng, M1
DeCicco-Skinner, KL; Dempsey, TA; Deshpande, MM; Nolan, SJ; Trovato, EL; Wiest, JS1
Bajpai, P; Kumar, S; Nigam, A; Priya, S1
Cescon, D; Chio, II; Dominguez-Brauer, C; Elia, AJ; Ghazarian, D; Gorrini, C; Haight, J; Hao, Z; Harris, IS; Inoue, S; Itsumi, M; Li, WY; Mak, TW; McCracken, S; Melino, G; Penn, LJ; Sasaki, M; Silvester, J; Snow, B; Ueda, T; Wakeham, A; Yamamoto, K; You-Ten, A; Zhou, L1
Arora, N; Bansal, MP; Koul, A1
Hong, JI; Jung, BG; Kim, TH; Ko, JH; Lee, BJ; Lee, JA; Park, YS1
Hanausek, M; Junco, JJ; Kowalczyk, MC; Kowalczyk, P; Slaga, TJ; Sosnowska, R; Tolstykh, O; Walaszek, Z1
Chen, H; Ding, F; He, H; Jin, Q; Li, Y; Liu, Z; Luo, A; Ma, J; Sunkel, B; Wang, Q; Xu, C; Zhang, S1
DiGiovanni, J; Jiang, G; Kiguchi, K; Rho, O1
Fujiwara, K; Ghosh, S; Liang, P; Morien, E; Nagase, H; Soma, M1
Ahn, JS; Bode, AM; Choi, TW; Dong, Z; Erikson, RL; Huang, Z; Hwang, J; Jang, JH; Kim, BY; Lee, KW; Li, W; Liu, H; Liu, K; Ryoo, IJ; Thimmegowda, NR; Yang, Y; Zhou, X1
Ali, F; Hamiza, OO; Hasan, SK; Khan, AQ; Khan, R; Lateef, A; Rehman, MU; Sultana, S; Tahir, M1
Scott, G1
Hogg, N; McNeill, E1
Conney, AH; Khor, TO; Kong, AN; Lee, JH; Lu, YP; Shu, L; Su, ZY; Wu, TY; Zhang, C1
Abel, EL; Beltran, L; Bozeman, R; Cheng, T; DiGiovanni, J; Macias, E1
Cline, JM; Endo, Y; Fonseca, LL; Ji, J; Lorenzo, PS; Rajani, C; Ramos, JW; Sharma, A; Stone, JC; Yanagida, JK1
Chawsheen, HA; Colburn, NH; Gerard, M; Jiang, H; Mishra, M; Toledano, MB; Wei, Q; Wu, L; Young, MR1
Cipolat, S; Hoste, E; Natsuga, K; Quist, SR; Watt, FM1
Aoto, Y; Goitsuka, R; Hachiya, T; Hirose, S; Isogai, E; Katsuragi, Y; Kominami, R; Nakamura, T; Okumura, K; Saito, M; Sakakibara, Y; Wakabayashi, Y1
Artoni, E; Corsi, L; Gatti, AM; Sighinolfi, GL1
Hisanaga, A; Hou, DX; Ishida, H; Kumamoto, T; Sakao, K; Sogo, T; Terahara, N; Wada, K1
Celis, E; Condamine, T; Donthireddy, L; Gabrilovich, D; Knight, SC; Kumar, V; Lee, GH; Lenox, B; Luetteke, N; Malietzis, G; Martner, A; Mony, S; Moorghen, M; Ortiz, ML; Seykora, J1
Carr, TD; Feehan, RP; Hall, MN; Rüegg, MA; Shantz, LM1
Anders, J; Blumenberg, M; Cataisson, C; Efimova, T; Kiss, A; Koppel, AC; Yuspa, SH1
Heo, YS; Jang, YJ; Jung, SK; Kim, JE; Kim, JR; Lee, CC; Lee, CY; Lee, E; Lee, HJ; Lee, JH; Lee, KW; Lim, SS; Lim, TG; Seo, SG; Son, JE1
Bao, R; Bechill, J; Bindokas, VP; Faber, PW; Lingen, MW; Spiotto, MT; Zhong, R1
Abdul Hamid, R; Khaza'ai, H; Mohtarrudin, N; Saiful Yazan, L; Yeong, LT1
de Gruijl, F; Rebel, H; Tensen, K; van de Glind, G; van Kempen, M1
Bountra, C; Guo, Y; Kong, AN; Pung, D; Shu, L; Su, ZY; Wang, L; Yang, Y; Zhang, C1
Dai, X; Dang, Y; Gu, J; Liu, M; Liu, X; Ren, X; Wang, L; Xu, P; Ye, X1
Berx, G; Declercq, W; Denecker, G; Devos, M; Gilbert, B; Haigh, J; Hochepied, T; Lambert, J; Lemeire, K; Leurs, K; Libbrecht, L; Lippens, S; Mc Guire, C; Van Den Broecke, C; Vandenabeele, P; Vuylsteke, M1
Asai, M; Asai, N; Enomoto, A; Kato, T; Mii, S; Murakumo, Y; Nagino, M; Shiraki, Y; Sunagawa, M; Takahashi, M1
Cheng, PS; Chung, WC; Hu, CC; Lee, YJ; Tseng, TH; Wang, CJ1
Bode, AM; Dong, Z; Heo, YS; Kang, NJ; Lee, HJ; Lee, KW; Oh, SM; Pugliese, A; Rogozin, EA1
Bility, MT; Blazanin, N; Devlin-Durante, MK; Glick, AB; Gonzalez, FJ; Kang, BH; Kennett, MJ; Peters, JM; Ward, JM1
Hori, Y; Iigo, M; Imai, T; Kitahashi, T; Sugimura, T; Takahashi, M; Takasuka, N; Wakabayashi, K; Yoshimi, N1
Ashton, GH; Baldeschi, C; Brunton, VG; Canel, M; Doyle, B; Frame, MC; Green, TP; Mackintosh, LJ; Mason, SM; Sansom, OJ; Serrels, A; Serrels, B1
Cataisson, C; Hennings, H; Jay, S; Ohman, R; Patel, G; Pearson, A; Tsien, M; Wright, L; Yuspa, SH1
Bode, AM; Cho, YY; Dong, Z; Ericson, ME; Ma, WY; Yao, K; Zheng, D; Zhu, F1
Antonucci, L; Canettieri, G; Coni, S; Della Guardia, M; Di Magno, L; Giannini, G; Gulino, A; Nocerino, V; Screaton, R; Screpanti, I1
Barragan, DI; Charron, J; Dumesic, PA; Harada, K; Khavari, PA; Scholl, FA1
Colburn, NH; Hou, DX; Murakami, A; Nishizawa, T; Ohigashi, H; Tanaka, T; Yasuda, M1
Cheepala, SB; Clifford, JL; Cvek, U; Gill, JN; Kleiner, HE; Loganantharaj, R; Lynch, M; McMillian, A; Syed, Z; Trutschl, M; Yin, W1
Bode, AM; Cho, YY; Dong, Z; Malakhova, ML; Pugliese, A; Yao, K1
Boily, G; He, XH; Jardine, K; McBurney, MW; Pearce, B1
Dziadziuszko, H; Glosnicka, R; Graczyk, A; Jankowski, D; Jaskiewicz, K; Juzeniene, A; Kaliszewski, M; Kunikowska, D; Kwasny, M; Kwitniewski, M; Ma, LW; Moan, J; Peksa, R1
Bandyopadhyay, S; Chrisler, WB; Opresko, LK; Quesenberry, RD; Tan, R; Waters, KM; Weber, TJ1
Anagnostopoulos, I; Jöhrens, K; Moos, V; Schneider, T1
Adegboyega, P; Batra, V; Cheepala, SB; Clifford, JL; Digiovanni, J; Gill, JN; Kleiner, HE; Nathan, C; Stein, J; Syed, Z1
Kim, DH; Liu, D; Na, HK; Park, JM; Surh, YJ1
Glick, AB; Hogan, KA; Markell, LM; Pérez-Lorenzo, R; Yuspa, SH1
Hitomi, T; Tanaka, R; Tokuda, H; Wada, S1
Decicco-Skinner, KL; Lepage, PK; Simmons, JK; Trovato, EL; Wiest, JS1
Coste, I; Druillennec, S; Eychene, A; Hainaut, P; Hmitou, I; Kfoury, A; Le Corf, K; Lebecque, S; Renno, T1
Fukami, K; Hara, E; Hirao, A; Ishikawa, Y; Motoi, N; Ohtani, N; Sone, S; Tajima, T; Takahashi, A; Takeuchi, S; Yamakoshi, K; Yanagi, S; Yoshimoto, S1
Pardoll, DM; Wang, L; Yi, T; Yu, H; Zhang, W1
Ahn, SG; Choi, HK; Choi, HS; Khanal, P; Kwon, SM; Namgoong, GM; Oh, WK; Yun, HJ1
Chen, L; Qin, Z; Wang, C; Xiao, M; Zhang, J1
Chao, DC; Ho, TY; Hsiang, CY; Kao, ST; Li, CC; Liang, JA; Lin, LJ; Lo, HY; Wu, SL1
Chang, CS; Chao, DC; Ho, TY; Hsiang, CY; Huang, HC; Kao, ST; Liang, JA; Lin, LJ; Wu, SL1
Ahn, SG; Choi, HK; Choi, HS; Khanal, P; Namgoong, GM; Sohn, H; Yoon, JH1
Lee, SJ; Mar, W; Nam, KW1
Arai, T; Hamashima, Y; Hasegawa, J; Kajimoto, T; Node, M; Suzuki, N; Tanaka, R; Tokuda, H; Tsujii, H; Yamada, T1
Barker, JR; Becker Buscaglia, LE; Choudhury, SN; Kanakamedala, K; Kumar, M; Li, Y; Liu, MF; Ma, X1
Codarin, S; Huang, TT; Kevil, CG; Richardson, A; Robbins, D; Shen, X; Van Remmen, H; Wang, F; Wittwer, JA; Zhao, Y1
Brotman, JJ; Judd, NP; Lewis, JS; Pittman, ME; Schreiber, RD; Uppaluri, R; Winkler, AE1
Fukayama, M; Fukushima, N; Ishikawa, S; Kokudo, N; Shibahara, J; Shinozaki, A; Tanaka, M; Umeda, M1
Bhui, K; Chaturvedi, PK; George, J; Roy, P; Shukla, Y; Singh, M; Srivastava, AK1
Kim, SH; Li, Q; Lu, H; Lu, HJ; Lu, Q; Sambandam, SA; Thomson, A; Xin, Y1
Boudreau, NS; Cayer, ML; Heckman, CA; Varghese, M1
Arbeit, JM; Chung, CH; Day, R; Dong, Y; Grabowska, D; Humphrey, P; Kladney, RD; Lewis, J; Li, A; Michel, LS; Wang, J; Weber, JD; Zhang, K1
DaSilva, SC; Konger, RL; Kozman, AA; Martel, KC; Rezania, S; Sahu, RP; Travers, JB; Warren, SJ; Yao, Y1
Bohrman, JS; Fischer, SM; Gleason, GL; Hardin, LG; Slaga, TJ1
Akihisa, T; Fukatsu, M; Kikuchi, T; Kimura, Y; Motoi, T; Seki, A; Suzuki, N; Tokuda, H1
Akihisa, T; Huang, Y; Inafuku, K; Kikuchi, T; Miura, M; Motohashi, S; Suzuki, N; Suzuki, T; Tokuda, H; Zhang, J1
Chen, C; Huang, Y; Li, Y; Ruan, Z; Zhang, D1
Cotsarelis, G; Gordon, D; Li, S; Liu, Y; Morris, RJ; Park, H; Trempus, CS1
Ai, W; Huang, S; Li, J; Liu, C; Wang, TC; Yu, F; Yu, T; Zheng, H1
Gong, JN; Luo, ZM; Shen, C; Tan, ZQ; Wang, F; Wang, XS; Yang, GH; Yin, XL; Yu, J; Zhang, JW; Zhang, XH1
Chae, JI; Cho, JH; Cho, MK; Kim, DJ; Lee, KA; Lee, SH; Nam, HS; Shim, JH; Woo, KM1
Eilers, M; Elsässer, HP; Hönnemann, J; Sanz-Moreno, A; Wolf, E1
Cho, YS; Cho, YY; Kim, DJ; Lee, KA; Lee, SH; Lee, YJ; Park, SY; Shim, JH; Woo, KM1
Adegboyega, P; Batra, V; Clifford, JL; Coburn, MA; DiGiovanni, J; Gill, JN; Kleiner-Hancock, HE; Mathis, JM; Shi, R; Syed, Z1
Alameda, JP; Bravo, A; Casanova, ML; Dupuy, AJ; Navarro, M; Page, A; Quintana, RM; Ramírez, A; Sánchez-Viera, M1
Clarke, M; Das, S; Huels, D; Jamieson, T; Jung, A; Neumann, J; Nibbs, RJ; Olson, MF; Samuel, MS; Sansom, OJ; Steele, CW1
Bonsignore, L; Drexler, SK; Gross, O; Hermeking, H; Jackstadt, R; Masin, M; Schneider, P; Tardivel, A; Tschopp, J; Yazdi, AS1
Belloli, S; Beltrami, E; Fassina, A; Fazio, F; Giorgio, M; Marcu, R; Moresco, R; Pelicci, P; Valtorta, S1
Li, W; Zhao, Y1
Chen, HD; He, CD; Liu, CH; Lu, T; Ma, GZ; Qiao, J; Wei, B; Wei, HC1
Jung, BG; Lee, BJ; Lee, JA1
Cho, NP; Cho, SD; Choi, ES; Li, C; Shin, JA1
Li, W; Liu, J; Zhao, Y1
Cheng, KH; Chiou, YS; Ho, CT; Pan, MH; Sang, S; Wang, YJ1
Anagnostopoulos, I; Bommert, K; Dörken, B; Hinz, M; Jundt, F; Krappmann, D; Lietz, A; Mathas, S; Mechta-Grigoriou, F; Scheidereit, C; Stein, H1
Conti, CJ; Kiyokawa, H; LaCava, M; Miliani de Marval, PL; Moons, DS; Rodriguez-Puebla, ML1
Brown, EM; Chattopadhyay, N; Tfelt-Hansen, J1
Chen, YC; Hou, WC; Ko, CH; Lee, WR; Lin, HY; Shen, SC; Yang, LL1
Black, EJ; Clark, W; Gillespie, DA; MacLaren, A; Walker, M1
Bortner, CD; Cannon, RE; Tennant, RW; Trempus, CS; Wei, SJ1
Bode, AM; Dong, Z; Liu, G; Ma, WY; Zhang, Y1
Grenman, R; Hieta, N; Impola, U; Jahkola, T; Jeskanen, L; Kähäri, VM; Saarialho-Kere, U; Suomela, S; Toriseva, M1
Fujii, M; Hou, DX; Li, JJ; Lin, S1
Aoki, M; Aronheim, A; Blazek, E; Kruse, U; Vogt, PK; Wasmer, S1
Kupper, TS; Morales, RE; Murphy, JE; Scott, J1
Wölfle, D1
Cao, M; Chang, PL; Hicks, P1
Colburn, N; Fujii, M; Hou, DX; Kai, K; Li, JJ; Lin, S; Terahara, N; Wakamatsu, M; Young, MR1
Bowden, GT; Chen, QM; Dilley, TK1
Albor, A; Babcock, M; Bowden, GT; El-Hizawi, S; Hennings, H; Horn, EJ; Kulesz-Martin, M; Liu, Y; Lozano, G; Vanderbeek, GE; Weinberg, WC1
Ali, RC; Hansen, LA; Tennant, RW; Trempus, CS; Wei, SJ1
Aronheim, A; Ben-Izhak, O; Heinrich, R; Livne, E1
Bowman, L; Castranova, V; Ding, M; Huang, C; Leonard, S; Lu, Y; Shi, X; Vallyathan, V; Wang, L1
Bernstein, LR; Samuel, S1
Chen, TJ; Chen, YC; Chien, LL; Lin, HY; Shen, SC1
Brindley, JM; Citro, ML; Colburn, NH; Dhar, A; Keefer, LK; Stark, C1
Hedley, D; Karasarides, M; Marais, R; Martin, J; Niculescu-Duvaz, D; Ogilvie, L; Springer, CJ; Wellbrock, C1
Colburn, NH; Dhar, A; Hu, J; Reeves, R; Resar, LM1
Barnes, J; Boudreau, N; Cayer, M; Hall, C; Heckman, CA; Kozma, R; Li, Y; Lim, L; Plummer, HK; Urban, JM1
Bode, AM; Cho, YY; Choi, BY; Choi, HS; Dong, Z; Mizuno, H1
Chimeno Zoth, SA; Collet, AM; Heber, E; Itoiz, ME; Schwint, AE1
Jahnen-Dechent, W; King, LE; Leite-Browning, ML; Matrisian, LM; McCawley, LJ; Ochieng, J1
Fisher, PB; Laskin, JD; Mufson, RA; Weinstein, IB1
Cao, ZY; Du, HJ; Liao, QP; Sun, YT; Zeng, Y; Zhao, J1
Chignell, CF; He, YY; Huang, JL1
Fujii, M; Hou, DX; Komine, S; Rabah, IO1
Benavides, F; Fischer, SM; Kim, E; Newman, RA; Rundhaug, JE; Yang, P1
Bowman, LL; Castranova, V; Ding, M; Feng, R; Jiang, BH; Leonard, SS; Lu, Y; Shi, X; Vallyathan, V1
Bai, Y; Edamatsu, H; Kataoka, T; Maeda, S; Saito, H; Satoh, T; Suzuki, N1
Blasco, MA; Cayuela, ML; Flores, JM1
Aplan, PD; Lin, YW; Slape, C; Zhang, Z1
Ao, L; Cao, J; Huang, MH; Liu, JY; Wu, YZ; Yang, MS; Zeng, ZX; Zhang, YQ1
Fischer, SM; He, G; Lubet, RA; Muga, S; Thuillier, P1
Bowman, LL; Castranova, V; Ding, M; Feng, R; Lu, Y; Qian, Y1
Adamson, ED; English, C; Krones-Herzig, A; Liang, H; Mercola, D; Mittal, S; Soni, T; Urcis, R; Yule, K1
Angel, P; Breitenbach, U; Fürstenberger, G; Gebhardt, C; Hess, J; Mauch, C; Richter, KH1
Liu, GT; Sun, H2
Beguinot, F; Formisano, P; Libertini, S; Miele, C; Oriente, F; Perruolo, G; Portella, G; Raciti, GA; Santopietro, S; Troncone, G1
Aoki, I; Colledge, WH; Foidart, JM; Hata, R; Kato, Y; Koshika, S; Kubota, Y; Nagashima, Y; Sakai, N; Thompson, EW; Tsukuda, M; Yao, M1
Hayashi, M; Kinae, N; Masuda, S; Mizuhashi, F; Nagai, M; Nakajima, M; Shimada, S; Sugiyama, C1
Furuya, T; Inomata, K; Kawauchi, S; Oga, A; Sasaki, K1
Fischer, SM; He, G; Sung, YM1
Araki, H; Asakura, M; Asasda, S; Baba, H; Fushiwaki, Y; Hamada, S; Kitou, N; Nakamura, T; Nakamura, Y; Ohmori, K; Oishi, H; Sakai, A; Sasaki, K; Sasaki, S; Shimada, S; Takagi, H; Tanaka, N; Tsuchiya, T; Umeda, M; Uno, Y; Washizuka, M; Yajima, S; Yamamoto, Y; Yamamura, E; Yatsushiro, T; Yoshimura, I1
Alexander, CL; Greenhalgh, DA; Porter, MJ; Quinn, JA; Wu, H; Yao, D1
Bai, Z; Cheng, B; He, P; Ke, L; Yu, Q1
Chen, Z; Hicks, J; Honeycutt, KA; Koster, MI; Miers, M; Nuchtern, J; Roop, DR; Shohet, JM1
Davies, R; Edwards, RE; Gant, TW; Greaves, P; Ridd, K; Smith, AG; Wolfreys, A; Zhang, SD1
Chen, YC; Chien, LL; Lee, HM; Lin, CW; Shen, SC1
Bakthavatchalu, V; Chaiswing, L; Oberley, TD; St Clair, DK; Zhao, Y1
Cameron-Smith, D; Carey, KA; Collier, GR; Klein, R; Sanigorski, A; Segal, D; Walder, K1
Aguilar-Quesada, R; García Del Moral, R; Martin-Oliva, D; Martínez-Romero, R; Muñoz-Gámez, JA; O'valle, F; Oliver, FJ; Piris, MA; Ruiz de Almodóvar, JM; Villuendas, R1
Bode, AM; Cho, YY; Dong, Z; He, Z; Mizuno, H; Seok Choi, H; Tatsumi, Y1
Denning, MF; Gerber, L; Gilliam, AC; Guo, H; Miao, H; Singh, J; Wang, B1
Beard, P; Chambon, P; Dubey, C; Dubois, N; Essers, MA; Hummler, E; Metzger, D; Offner, S; Oskarsson, T; Roger, C; Trumpp, A1
Chan, EL; Collins, MH; Kader, SA; Pathrose, P; Peace, BE; Toney, K; Waltz, SE1
Choi, HG; Kim, JA; Kim, SJ; Lee, ES; Lee, YS; Paek, SH; Park, BC; Yong, CS1
Castranova, V; Kisin, ER; Kommineni, C; Murray, AR; Shvedova, AA; Vallyathan, V1
Antal, MC; Castaneda, E; Chambon, P; Desvergne, B; Gariglio, P; Indra, AK; Jiang, M; Kato, S; Loehr, CV; Meng, X; Messaddeq, N; Metzger, D; Wahli, W1
Hur, HJ; Kwon, JY; Lee, HJ; Lee, KW1
Niemann, C; Owens, DM; Schettina, P; Watt, FM1
Gu, Q; Sun, Y; Tan, M1
Chen, TT; Gao, J; Pan, LL; Sun, L; Yuan, LX; Zhou, CY; Zhu, YP1
Bae, DS; Darwiche, N; Glick, AB; Hennings, H; Perez-Lorenzo, R; Ryscavage, A; Wright, L; Yuspa, SH1
Chiu, RJ; Meyskens, FL; Misner, BJ; Yang, S1
Fischer, SM; Kim, E; Pavone, A; Rundhaug, JE1
Horie, S; Katsuki, M; Muto, S1
Bode, AM; Bowden, GT; Cho, YY; Dong, Z; Kang, NJ; Kim, HG; Lee, HJ; Lee, KW; Rogozin, EA; Surh, YJ1
Andrée, B; Bylaite, M; Kellermann, S; Kloepper, JE; Paus, R; Reifenberger, J; Rüther, U; Ruzicka, T; Walz, M1
Bower, KA; Chen, G; Ding, M; Gao, TW; Gao, Y; Ke, Z; Luo, J; Ma, C; Odetallah, M; Wang, J1
Abel, E; Beltran, L; Carbajal, S; Chan, KS; Clifford, J; Digiovanni, J; Kataoka, K; Peavey, M; Sano, S; Shen, J1
Bode, AM; Cho, YY; Dong, Z; Kang, BS; Kim, HG; Yao, K; Zheng, D1
Bowden, GT; Gu, Q; Normolle, D; Sun, Y1
Dai, C; Lindquist, S; Rogers, AB; Whitesell, L1
Kim, Y; Klein-Szanto, A; Macias, E; Miliani de Marval, PL; Rodriguez-Puebla, ML1
Hara-Chikuma, M; Verkman, AS1
Chiappetta, G; Costinean, S; Croce, CM; De Martino, I; Fedele, M; Fusco, A; Iuliano, R; Kusewitt, DF; Oberyszyn, TM; Palmieri, D; Server, IN; Visone, R1
Gao, J; Huang, C; Li, J; Ouyang, W; Song, L; Zhang, D1
Bode, AM; Bowden, GT; Dong, Z; Heo, YS; Hwang, MK; Kang, NJ; Lee, HJ; Lee, KW; Pugliese, A; Rogozin, EA1
Baker, AR; Colburn, NH; Hagan, JP; Hegamyer, G; Jansen, AP; Schmid, T1
Choi, HK; Choi, HS; Ermakova, SP; Kusaykin, MI; Lee, NY; Shevchenko, NM; Zvyagintseva, TN1
Arlt, VM; Baird, WM; Bildfell, R; Courter, LA; Fischer, K; Luch, A; Musafia-Jeknic, T; Pereira, C; Phillips, DH; Poirier, MC1
Bode, AM; Cho, YY; Dong, Z; Kang, NJ; Kim, HG; Lee, KW; Oh, SM1
Krishnan, R; Maru, G; Patel, R; Ramchandani, A1
Carbajal, S; Clifford, JL; DiGiovanni, J; Kataoka, K; Kim, DJ1
Beltran, L; Carbajal, S; Digiovanni, J; Hursting, SD; Leroith, D; Moore, T; Perkins, SN; Yakar, S1
Guo, QN; Li, Y; Meng, G1
Fujita, J; Sugawara, K; Tokuda, H; Yoshida, O1
Deegan, MJ; Maeda, K1
Hirakawa, T; Kakunaga, T; Shimomura, K; Sugimura, T1
Arcoleo, J; Backer, J; Gattoni-Celli, S; Hsiao, WL; Jeffrey, A; Kirschmeier, P; Okin, E; Weinstein, IB1
Dorsch-Häsler, K; Fisher, PB; Ginsberg, HS; Weinstein, IB1
Hennings, H; Kulesz-Martin, M; Lichti, U; Yuspa, SH1
Kaufman, DG; Siegfried, JM1
Ben, T; Lichti, U; Yuspa, SH1
Andreotti, PE1
Borek, C; Troll, W1
Emmerson, A; Grabham, P; Parkinson, EK1
Kakinuma, K; Kitagawa, S; Miura, Y; Nojiri, H; Ohta, M; Saito, M; Takaku, F1
Emmerson, A; Parkinson, EK1
Emmerson, A; Gorman, PA; Parkinson, EK; Pera, MF1
Antecol, MH; Mukherjee, BB1
Bollum, FJ; Breviario, D; LeBien, TV; Sacchi, N; Trost, S1
Leister, KJ; Tomei, LD; Wenner, CE1
Fisher, PB; Lee, LS; Weinstein, IB1
Seif, R1
Borek, C; Geard, CR; Guernsey, D; Mason, H; Miller, RC; Ong, A; Osmak, RS; Rutledge-Freeman, M1
Colburn, NH; Gindhart, TD1
Weinstein, IB3
Hemstad, J; Rivedal, E; Sanner, T1
Chechik, BE; Gelfand, EW; Letarte, M; Mak, TW; Nagasawa, K; Sengupta, S1
DiPaolo, JA; Evans, CH1
August, JT; Skubitz, KM; Zhen, YS1
De Larco, JE; Shoyab, M; Todaro, GJ1
Bockman, RS; Honn, KV; Marnett, LJ1
Rivedal, E2
Davies, C; Rivedal, E; Sanner, T1
Georg-Fries, B; Mueller-Lantzsch, N1
Rivedal, E; Sanner, T3
Abutbul, H; Rotter, V; Wolf, D1
Borek, C1
Herschman, HR1
Poulin, L; Wainberg, MA1
Abe, E; Chida, K; Kuroki, T; Sasaki, K; Suda, T1
Iyer, N; King, L; Krebs, C; Kucera, LS; Waite, BM1
Billing, R; Bohman, R; Koeffler, HP; Ranyard, J; Yelton, L1
Haugen, A; Lechner, JF; McClendon, IA; Tokiwa, T1
Nagasawa, K1
Dokhelar, MC; Fradelizi, D; Harel, A; Tursz, T; Wakasugi, H1
Colburn, NH; Gindhart, TD; Lerman, MI; Nakamura, Y; Srinivas, L1
Borek, C; Cleaver, JE; Fujiki, H1
Yuspa, SH2
Butler, AP; Slaga, TJ1
DiPaolo, JA; Evans, CH; Greiner, JW1
Dederer, E; Goerttler, K; Hesse, B; Loehrke, H; Rosenkranz, G; Schweizer, J1
Liu, CK; Qian, GX; Rosen, A; Schmied, R; Schreiber, C; Waxman, S1
Harris, CC; Lechner, JF; Ozanne, C; Saladino, AJ; Willey, JC1
Cerutti, P; Zimmerman, R1
Carter, C; Dehazya, P; Gilmore, T; Martin, GS; Moss, P; Radke, K1
Blenis, J; Hawkes, SP1
Fürstenberger, G; Goerttler, K; Kinzel, V; Loehrke, H; Marks, F1
Gattoni-Celli, S; Hsiao, WL; Weinstein, IB1
Chou, TC; Kopelovich, L1
Barrett, JC; Gray, TE; Mass, MJ; Nettesheim, P; Steele, VE1
Fürstenberger, G; Marks, F3
Baumbach, L; Sydow, G; Wunderlich, V1
Gelfand, EW; Letarte, M; Okamura, J; Sigal, NH; Stein, LD1
Borek, C; Geard, CR; Guernsey, DL; Miller, RC; Smith, JE1
Copley, MP; Gindhart, TD; Stevens, L1
Cerni, C2
Gainer, HS; Kinsella, AR; Schor, S1
Kennedy, AR; Little, JB; Troll, W1
Kennedy, AR; Radner, BS1
Cohen, M; Colburn, NH; Dion, LD; Gindhart, TD; Hegamyer, GA; Srinivas, L; Wendel, EJ1
Bertram, JS; Hui, SW; Mordan, LJ1
Blaese, RM; Decker, JM; Hall, RE; Muchmore, AV1
Price, BJ; Whittington, K; Zucker, RM1
Kornatowski, G; Kumar, SA; O'Connor, D; Walsh, J; Yourno, J1
Aman, P; Biberfeld, P; Gordon, J; Klein, G; Mellstedt, H1
Grotendorst, GR1
DeMarinis, AJ; DiPaolo, JA; Doniger, J; Evans, CH3
Colburn, NH; Srinivas, L2
Dutton, RW; Swain, SL; Wetzel, GD1
Brodie, RA; Gans, PJ; Larsen, NE; McCarroll, LA; Sullivan, R1
Kadin, ME; Nasu, K; Sako, D; Su, IJ1
DiPaolo, JA2
Fusenig, NE1
Colburn, NH; Gindhart, TD; Talmadge, CB2
Gainer, HS; Kinsella, AR1
Abernethy, DJ; Boreiko, CJ; Frazelle, JH2
Alitalo, K; Hautanen, A; Keski-Oja, J; Rapp, UR1
Kokunai, T; Matsumoto, S; Tamaki, N; Taomoto, K1
Kopelovich, L4
Enaka, K; Ono, T; Umeda, M1
Kennedy, AR; Long, SD; Quigley, JP; Troll, W1
Fisher, PB; Fujiki, H; Miranda, AF; Mufson, RA; Sugimura, T; Weinstein, IB; Weinstein, LS1
Abernethy, DJ; Boreiko, CJ; Frazelle, JH; Ragan, DL1
Sugimura, T1
Wigley, CB1
Colburn, N; Copley, M; Gindhart, T1
Fjose, A; Kleppe, K; Lillehaug, JR; Pryme, IF1
Nettesheim, P; Steele, V; Vanderlaan, M1
Ben, T; Hennings, H; Kulesz-Martin, M; Yuspa, SH1
Bradley, MO; Diamond, L; O'Brien, TG; Sina, JF1
Mahlum, DD; Springer, DL; Swanger, D1
Belman, S1
Boreiko, CJ; Butterworth, BE; Dorman, BH1
Abrahm, J; Cooper, RA; Lange, B; Levis, A; Meo, P; Pegoraro, L; Rovera, G1
Cooper, RA; Ip, SH1
Cassileth, PA; Cooper, RA; Suholet, D1
Abruzzo, G; Ben, T; Colburn, NH; Jardini, E; Lichti, U; Ozanne, S; Wendel, E; Yuspa, SH1
Ben, T; Hennings, H; Lichti, U; Yuspa, SH1
Ip, SH; Lebman, D; Perussia, B; Rovera, G; Trinchieri, G1
Abruzzo, G; Colburn, NH; Wendel, EJ1
Bussolino, F; Camussi, G; Ghezzo, F; Pegoraro, L1
Bosmann, HB; Miska, D1
Colburn, NH; Gindhart, TD; Srinivas, L2
Bateman, J; Bear, J; Colburn, NH; De Luca, LM; Dion, LD1
Brown, G; Bunce, CM; Michell, RH; Stone, PC; Toksoz, D1
Carchman, RA; Laskin, DL; Laskin, JD; Weinstein, IB1
Hoffman-Liebermann, B; Liebermann, D; Sachs, L1
Ashman, RF; Billing, R; Chan, G; Golde, DW; Lusis, AJ; Weisbart, RH1
Kennedy, AR; Little, JB2
De Luca, LM; Jetten, AM1
Evans, CH; Ransom, JH1
Halper, JP; Pernis, B; Roth, P; Weinstein, IB1
Bonnard, GD; Fruehauf, JP; Herberman, RB1
Croop, J; Dlugosz, AA; Holtzer, H; Toyama, Y1
Blumberg, PM2
Friedman, EA1
Cherington, PV; Medrano, EE; Pardee, AB1
Bollum, FJ; Kersey, JH; LeBien, TW; Yasmineh, WG1
Dzarlieva, RT; Fusenig, NE1
Chang, C; Trosko, JE; Tsushimoto, G; Warren, ST; Yotti, LP1
Sachs, L; Symonds, G1
Sivak, A1
Elkind, MM; Han, A1
Diamond, L; O'Brien, TG; Saladik, D2
Kinzel, V; Krombholz-Nolinski, I; Richards, J; Stöhr, M1
Cockle, SM; Dean, RT1
Colburn, NH; Dion, LD; Wendel, EJ1
DiPaolo, JA; Doniger, JN; Evans, CH; Popescu, NC1
Argyris, TS1
Bergin, LM; Bertram, JS; Budnick, JE; Meegan, RR; Mordan, LJ1
Backer, JM; Boersig, MR; Weinstein, IB1
Cooper, PD; Marshall, SA; Masinello, GR1
Albino, AP; Cairncross, JG; Eisinger, M; Houghton, AN; Old, LJ1
Bias, NE; Kopelovich, L1
Claisse, PJ; Hince, TA; Roscoe, JP; Winslow, DP1
Sivak, A; Tu, AS1
Fisher, PB; Weinstein, IB1
Hennings, H; Lichti, U; Morgan, D; Yuspa, SH1
Marchok, AC; Nettesheim, P; Steele, VE2
Boreiko, CJ; Ragan, DL1
Hennings, H; Lichti, U; Yuspa, SH1
Arnstein, P; Huebner, RJ; Rhim, JS1
Marsh, WH; Parsa, I; Sutton, AL1
Kennedy, AR; Little, JB; Murphy, G1
Bärlin, E; Gemsa, D; Grimm, W; Kramer, W; Leser, HG1
Borek, C; Geard, CR; Harisiadis, L; Mason, H; Miller, RC; Napholz, A; Ong, A; Osmak, RS; Perez, N; Rutledge-Freeman, M1
Hayashi, M; Honma, M; Mizusawa, H; Ohno, T; Sasaki, K; Sofuni, T; Tanaka, N1
Eckhardt, JN; Greenhalgh, DA; Roop, DR; Wang, XJ1
Chang, RL; Conney, AH; Fisher, C; Huang, MT; Lu, YP; Ma, W; Manchand, PS; Newmark, HL1
Owens, DM; Smart, RC; Spalding, JW; Tennant, RW1
Biaglow, J; Kennedy, SH; Manevich, Y1
Tsuchiya, T; Umeda, M2
Kennedy, AR2
Garrido, C; Gospodarowicz, D; Li, RP; Samarut, J; Saule, S1
Albino, AP; Dosik, JS; Loganzo, F; Nanus, DM; Sudol, M; Vidal, MJ; Zhao, Y1
Miyata, N; Sakai, A; Takahashi, A2
Ip, C; Scimeca, JA; Thompson, HJ1
Rubin, AL1
Ben-Ari, ET; Bernstein, LR; Birrer, MJ; Colburn, NH; Watts, RG; Wendel, E; Winterstein, D1
Mukherjee, AB; Mukherjee, BB; Su, L1
Chang, PL; Prince, CW; Yang, WC1
Aloj, SM; Bifulco, M; Laezza, C; Perillo, B; Romano, A; Santillo, M; Tedesco, I1
Qiu, SL; Wang, ML; Wu, J; Xu, Z; Zhu, DX; Zhu, JQ1
Fürstenberger, G; Marks, F; Müller-Decker, K; Scholz, K1
Asano, Y; Enomoto, T2
Bessi, H; Nguyen-Ba, G; Rast, C; Rether, B; Vasseur, P1
Kennedy, AR; Krinsky, NI1
Dertinger, SD; Tometsko, AM; Torous, DK1
Cao, J; Elkind, MM; He, L; Wells, RL; Xing, Y1
Cmarik, JL; Colburn, NH; Herschman, H1
Boukamp, P; Fitzgerald, DJ; Fusenig, NE; Mesnil, M; Piccoli, C; Yamasaki, H1
Israel, L; Mainguene, C; Nehme, A; Planchon, P; Prevost, G; Salle, V; Spanakis, E; Starzec, AB; Valette, A; Veber, N1
Cecchi, C; Mapelli, E; Sanfilippo, O; Supino, R1
Chang, RL; Conney, AH; Huang, MT; Lou, YR; Lu, YP; Newmark, HL; Reuhl, KR1
Elkind, MM1
Guo, CY; Han, R1
Haliday, E; Hirst, M; Lou, L; Nakamura, J1
Coppock, DL; Nathanson, L1
Hall, EJ; Hei, TK; Piao, CQ; Thomas, S; Willey, JC1
Rubin, AL; Rubin, H1
Cmarik, JL; Colburn, NH; Dong, Z; Wendel, EJ1
Bhisey, RA; Borges, AM; Ramchandani, AG1
Frampton, J; Graf, T; Kraut, N; McNagny, KM1
Birrer, MJ; Colburn, NH; Dong, Z; Matrisian, LM; Watts, RG1
Lipsick, JS; Smarda, J1
Borek, C; Merrill, AH1
Arita, Y; O'Driscoll, KR; Weinstein, IB1
Finkenzeller, G; Heidecker, G; Hummel, R; Kochs, G; Kolch, W; Marmé, D; Mischak, H; Rapp, UR; Vahidi, H1
Cacace, AM; Fabbro, D; Guadagno, SN; Krauss, RS; Weinstein, IB1
Brückner, A; Tony, HP; Wilhelm, M1
Honda, I; Nishi, Y; Semba, M; Shibagaki, M1
Garrett, LR; McDougall, JK; Perez-Reyes, N; Smith, PP1
Rivedal, E; Roseng, LE1
Bols, BL; Gillis, KC; Lohman, PH; Naaktgeboren, JM; Niericker, M; Simons, JW1
Bishop, JM; McMahon, M; Samuels, ML; Weber, MJ1
Bassin, RH; Heidecker, G; Kolch, W; Rapp, UR; Troppmair, J; Yanagihara, K1
Autrup, H; Christensen, B; Kieler, J; Skouv, J1
Mikalsen, SO; Sanner, T1
Harris, PE; Hong, B; Lupu, F; Reed, EF; Suciu-Foca, N1
Atherton, GT; Bianchi, SM; Deed, RW; Johnston, D; Murphy, JJ; Norton, JD; Santibanez-Koref, M1
Blackshear, PJ; Macara, IG; Stumpo, DJ; Wojtaszek, PA1
Blumberg, PM; Goodnight, JA; Kazanietz, MG; Kolch, W; Martiny-Baron, G; Mischak, H; Mushinski, JF; Pierce, JH; Schaechtle, C1
Alani, R; Birrer, MJ; Brown, PH; Preis, LH; Szabo, E1
Ackland-Berglund, CE; Cuchens, MA; Garrett, LR; Jones, CJ1
Chang, PL; Prince, CW1
Craig, RW; Guggino, WB; Lu, L; Markakis, D; Yang, T1
Adey, WR; Cain, CD; Thomas, DL2
Arbeit, JM; Ayer, DE; Eisenman, RN; Foley, KP; Hanahan, D; Hurlin, PJ1
Engelmann, H; Hess, S1
Dusinská, M; Kolman, A1
Colburn, NH; Dawson, MI; Dong, Z; Li, JJ1
Hakomori, S; Igarashi, Y; Masamune, A; Ohta, H; Sakakura, C; Shirahama, T; Sweeney, EA1
Colacci, A; Da Vià, C; Grilli, S; Horn, W; Manzini, E; Perocco, P; Silingardi, P; Vaccari, M1
Herlyn, M; Montone, KT; Nesbit, M; Satyamoorthy, K; Soballe, PW1
Folini, M; Lin, HC; Mischak, H; Perletti, GP; Piccinini, F; Tashjian, AH1
Harms-Ringdahl, M; Kolman, A1
Marquardt, H; Wölfle, D1
Colburn, N; Dong, Z; Lavrovsky, V; Ma, WY1
Degawa, H; Nakamura, A; Nakaoka, R; Tsuchiya, T1
George, K; Kampherstein, JA; Laughlin, KV; Mullin, JM; O'Brien, TG; Russo, LM; Saladik, DT; Shurina, RD; Soler, AP1
Donehower, LA; Greenhalgh, DA; Roop, DR; Wang, XJ1
Isfort, RJ; Kerckaert, GA; LeBoeuf, RA1
Agarwal, R; Ahmad, N; Mohan, RR; Mukhtar, H1
Cano, A; Conti, CJ; Duran, H; Jorcano, JL; Larcher, F; Murillas, R; Quintanilla, M; Robles, AI1
Cacace, AM; Han, EK; Kolch, W; Philipp, A; Ueffing, M; Weinstein, IB1
Caldeira, AA; Parfett, CL; Pilon, R1
Dong, Z; Huang, C; Ma, WY; Schmid, HH; Schmid, PC1
Amstad, PA; Berezesky, IK; Ichimiya, M; Liu, H; Trump, BF1
Brown, RE; Dong, Z; Huang, C; Ma, WY1
Baldi, A; Mladovan, AG; Shayo, CC1
Foster, DA; Hornia, A; Jiang, YW; Lu, Z; Ohno, S; Zang, Q1
Chen, Z; He, Z; Shao, X; Yao, K1
Colburn, NH; Dong, Z; Strickland, J; Sun, Y1
Dorsman, JC; Israël, A; Schouten, GJ; Toebes, M; van der Eb, AJ; Vertegaal, AC; Whiteside, ST; Zantema, A1
Dong, Z; Hecht, SS; Huang, C; Ma, WY1
Chen, G; Colburn, NH; Saffer, JD; Thurston, SJ1
Colburn, NH; Crawford, HC; Dong, Z; Lavrovsky, V; Matrisian, LM; Taub, D; Watts, R1
Hamano, T; Konoshima, T; Takasaki, M; Tokuda, H; Yasuda, I1
Benehacene, A; Kamps, M; Scheele, JS; White, FC1
Colburn, NH; Ghosh, P; Li, JJ; Westergaard, C1
Lee, SF; Lin, JK1
Ji, ZW; Li, BM; Liu, ZS; Zeng, Y1
Fischer, SM; Li-Stiles, B; Lo, HH1
Dong, Z; Huang, C; Ma, W; Yang, CS1
Chang, PL; Garretson, K; Lee, TF; Prince, CW1
Amstad, PA; Berezesky, IK; Chang, S; Ichimiya, M; Liu, H; Trump, BF1
Gong, Y; Shou, J; Wu, D1
Chen, ZH; Gopalakrishna, R; Gundimeda, U1
Kaneko, T; Miyazaki, K; Moriyama, K; Okubo, T; Sakamoto, Y; Shoji, A; Tsuchiya, T; Umeda, M1
Linder, S; Ljungdahl, S; Shoshan, MC; Sollerbrant, K; Svensson, C1
Colburn, N; Dong, Z; Huang, C; Ma, WY; Young, MR1
Gschwendt, M; Kittstein, W; Krammer, PH; Möller, P; Sträter, J; von Reyher, U1
Acs, P; Blumberg, PM; Goodnight, J; Mischak, H; Mushinski, JF; Wang, QJ1
Bessi, H; Cruciani, V; Dhalluin, S; Elias, Z; Gate, L; Nguyen-Ba, G; Pages, N; Poirot, O; Rast, C; Tapiero, H; Vasseur, P1
Aiba, S; Tagami, H1
Darwiche, N; De Luca, LM; Gartsbein, M; Hansen, L; Hennings, H; Lowry, D; Morgan, DL; Tennenbaum, T; Yuspa, SH1
Cacace, AM; Han, EK; Marmè, D; Ueffing, M; Weinstein, IB1
Buddenbaum, W; Elkind, MM; Hill, CK; Hu, Q; Wells, RL; Xing, Y1
Lavrovskiĭ, VA; Subkhankulova, TN1
Janik, P; Kowalczyk, D; Miłoszewska, J1
Cmarik, JL; Colburn, NH; Li, Y; Min, H; Ogram, SA; Reeves, R1
Hui, SW; Jahreis, GP; Johnson, PG; Zhao, YL1
Colburn, NH; Dong, Z; Huang, C; Li, JJ; Pennie, WD; Watts, RG; Young, MR1
Snawder, JE1
Chow, DA; Wang, H1
Dhalluin, S; Elias, Z; Gate, L; Nguyen-Ba, G; Pages, N; Poirot, O; Tapiero, H; Vasseur, P1
Fusco, A; Li, Z; Portella, G; Santoro, M; Sferratore, F; Vecchio, G; Vitagliano, D1
Arturi, F; Chiefari, E; Filetti, S; Fusco, A; Iuliano, R; Russo, D; Stella, A; Trapasso, F1
Bahram, F; Larsson, LG; Lüscher, B; Oberg, F; Wu, S1
Matsunaga, S; Tanaka, R1
Chen, XN; Elisei, R; Fagin, JA; Gonsky, R; Knauf, JA; Korenberg, JR; Liron, T; Mochly-Rosen, D1
Colburn, N; Flavell, RA; Hunziker, R; Li, JJ; Rincón, M; Sathyanarayana, BK; Young, MR1
Jiang, J; Wu, Y; Yu, B; Yu, Z1
Gurley, KE; Kemp, CJ; Philipp, J; Seidel, K; Vo, K1
Owens, DM; Smart, RC; Wei, S1
Dong, Z; Huang, C; Li, J; Ma, WY1
Foster, DA; Frankel, P; Hornia, A; Joseph, T; Lu, Z; Sukezane, T; Zhong, M1
Colburn, NH; Jansen, AP; Verma, AK1
Greenhalgh, DA; Liefer, KM; Roop, DR; Wang, XJ1
Cmarik, JL; Colburn, NH; Hegamyer, G; Kulesz-Martin, M; Matsuhashi, S; Min, H; Yoshinaga, H; Zhan, S1
Hiranuma, H; Jikko, A; Maeda, T1
Dartsch, D; Marotzki, S; Marquardt, H; Schäfer, W; Wölfle, D1
Gau, E; Geisen, C; Haas, K; Karsunky, H; Möröy, T; Schmidt, T; Zevnik, B1
Chou, C; Lin, Y; Mettling, C1
Ali, AM; Koshimizu, K; Mat-Salleh, K; Murakami, A; Ohigashi, H1
Heckman, CA; Mukherjee, R; Plummer, HK1
Guan, KL; Stewart, S1
Blalock, WL; Bosch, E; Cherwinski, H; Franklin, RA; Hoyle, PE; McCubrey, JA; McMahon, M; Moye, PW; Pearce, M; Steelman, LS1
Acs, P; Beheshti, M; Blumberg, PM; Li, L; Szállási, Z; Yuspa, SH1
Chambers, AF; Chang, PL1
Nakamura, Y; Noda, Y; Noro, K; Noro, T; Ohki, T; Tomita, I; Warashina, T1
Blank, M; Goodman, R; Jin, M1
Cmarik, J; Colburn, NH; Hsu, TC; Young, MR1
Conigrave, AD; Morris, MB; van der Weyden, L1
Brinkley, BR; Go, C; He, W; Huang, J; Li, P; Wang, XJ; Zhong, L1
Beltrán, L; Bol, D; Carbajal, S; Chan, K; DiGiovanni, J; Jorcano, J; Kiguchi, K; Moats, S1
Bode, AM; Chen, N; Dong, Z; Ma, W; Nomura, M1
Bureau, JP; Carillo, S; Guiraud, I; Henry, L; Lavabre-Bertrand, T1
Kato-Masatsuji, E; Tsuchiya, T; Tsuzuki, T; Umeda, M1
Dolnikov, A; Millington, M; Sun, LQ; Symonds, G1
Colburn, NH1
Klein-Szanto, A; Zhang, S1
Cmarik, JL; Colburn, NH; Jansen, AP; Nair, R; Shibahara, K; Verma, AK; Yang, HS1
Abbas, T; Barile, N; Chatakondu, K; Foster, DA; Hornia, A; Kaplan, P; Lu, Z; Zhong, M1
Bode, AM; Chen, N; Dong, Z; Flavell, RA; Ma, WY; Nomura, M; She, QB; Wang, L1
Camalier, CE; Colburn, NH; Hegamyer, GA; Hsu, TC; Nair, R; Tulsian, P; Young, MR1
Peng, Z; Wei, Y; Zhao, X1
Cho, MH; Fang, MZ; Kim, DY; Lee, HW1
Bibus, DM; Bode, AM; Dong, Z; Holman, RT; Liu, G; Ma, WY1
Dong, Z; Kaji, A; Ma, W; Miyamoto, K; Nomura, M1
Owens, DM; Watt, FM1
Kriehuber, R; Richard, D; Simkó, M; Weiss, DG1
DiPaolo, JA; Doniger, J; Evans, CH; Popescu, NC2
Bode, A; Dong, Z; Ho, CT; Liu, G; Ma, WY; Sang, S1
Sakai, A1
Bode, AM; Chen, N; Dong, Z; Liu, G; Ma, WY; She, QB; Wu, E1
Fujiki, H; Iida, N; Kishimoto, T; Kurusu, M; Ohshima, S; Okabe, S; Saeki, Y; Suganuma, M1
Conti, CJ; Gómez-Casero, E; Jorcano, JL; Larcher, F; Navarro, M; Paramio, JM; Rodríguez-Puebla, ML1
Czaja, MJ; Dannenberg, AJ; de Lédinghen, V; Liu, H; Lo, CR; Subbaramaiah, K; Zhang, F1
Brown, N; Bucheimer, N; Chapp, C; Colburn, NH; Hsu, TC; Nair, R; Tulsian, P; Young, MR1
Davie, JR; Strelkov, IS1
Clark, SS; Elegbede, JA; Jenkins, GJ; Perman, SM; Sahin, MB1
Bias, NE; Helson, L; Kopelovich, L1
Christman, JK; Copp, RP; Pedrinan, L; Whalen, CE1
Chouroulinkov, I; Lasne, C1
Fisher, PB; Goldstein, NI; Weinstein, IB1
Stenbäck, F1
Blumberg, PM; Driedger, PE1
Goldfarb, RH; Quigley, JP1
Easton, TG; Maelicke, A; Miskin, R; Reich, E1
Easton, TG; Miskin, R; Reich, E1
Bissell, MJ; Calvin, M; Hatié, C1
Reich, E; Wilson, EL1
Blumberg, PM; Delclos, KB1
Edwards, CA; Martin, RG; Setlow, VP; Vembu, D1
Basilico, C; Zouzias, D1
Comoglio, PM; Monti-Bragadin, C; Pani, B; Prat, M; Tarone, G1
Eisenberg, D; Fisher, PB; Ginsberg, HS; Weinstein, IB1
Kinsella, AR; Radman, M1
Marx, JL1
Bozzone, JH; Fisher, PB; Weinstein, IB1
Fisher, PB; Lee, LS; Mufson, A; Weinstein, IB; Yamasaki, H1
Goerttler, K; Komitowski, D; Löhrke, H1
Kennedy, AR; Little, JB; Nagasawa, H1
Colburn, NH; Former, BF; Nelson, KA; Yuspa, SH1
Diamond, L; O'Brien, TG3
Brankow, DW; Heidelberger, C; Mondal, S; Peterson, AR; Thon, W1
Holtzer, H; Pacifici, M1
Heidelberger, C; Kennedy, AR; Little, JB; Mondal, S1
Bates, JR; Bruegge, WF; Colburn, NH; Gray, RH; Kelsey, WH; Rossen, JD; Shimada, T1
Getz, MJ; Moses, HL; Proper, JA; Volkenant, ME; Wells, DJ1
Brankow, DW; Heidelberger, C; Mondal, S2
Heidelberger, C; Mondal, S1
Pienta, RJ; Poiley, JA; Raineri, R1
Blumberg, PM; Driedger, PE; Rossow, PW1
Weinstein, IB; Wigler, M1
Hilberg, F; Wagner, EF1
Endo, Y; Kida, Y; Mai, M; Sasaki, T; Sato, H; Seiki, M; Tanaka, J1
Inoue, T; Ishida, Y; Kaku, K; Kaneko, T; Sasaki, H; Yoshida, T1
Caamano, J; Garcia-Palazzo, I; Harris, CC; Iizasa, T; Klein-Szanto, AJ; Metcalf, R; Momiki, S; Welsh, J1
Cabot, MC; Huang, C1
Daub, R; Garcia, JG; Harrington, MA; Song, A; Stasek, J1
Hu, P; Li, W; Schlessinger, J; Skolnik, EY; Ullrich, A1
Enomoto, T; Sawada, S; Tauchi, H1
Glick, A; Greenhalgh, D; Hennings, H; Morgan, D; Welty, D; Yuspa, SH1
Dlugosz, AA; Mischak, H; Mushinski, JF; Yuspa, SH1
Dougherty, N; Larue, L; Mintz, B; Porter, S1
Holmsen, H; Lillehaug, JR; Skar, R; Vassbotn, FS1
Rivedal, E; Roseng, LE; Sanner, T1
Jooss, K; Müller, R1
Baxter, CS; Leikauf, GD; Smith, JS; Wey, HE1
Zwijsen, RM1
Kumar, S; Rani, AS1
Hosick, HL; Kanazawa, T1
Auwerx, J; Sassone-Corsi, P1
Lin, JK; Wu, FY; Wu, WS1
Aguelon, AM; Nakazawa, H; Yamasaki, H1
Albino, AP; Houghton, AN; Jhanwar, SC; Nanus, DM; Sozzi, G1
Hawkes, SP; Yang, TT1
Bernstein, LR; Bravo, R; Colburn, NH1
Mesnil, M; Nakazawa, H; Yamasaki, H1
Borowski, P; Buck, F; Fanick, W; Harbers, M; Hilz, H; Hinsch, KD; Lengyel, H1
Kato, R; Wang, JC; Yamamoto, S1
Ben-Ari, ET; Bernstein, LR; Colburn, NH1
Boswell, HS; Burgess, GS; Litz-Jackson, S; Miller, AH1
Colburn, NH; Hirano, K; Smith, BM1
Benusiglio, E; Granger-Schnarr, M; Sassone-Corsi, P; Schnarr, M1
DiGregorio, FM; Hashimoto, K; Ishihara, M; Pietruk, T; Richards, J; Setoyama, M; Zarbo, RJ1
Birnie, GD; Mitchell, LS; Neill, RA1
Chang, C; Kumar, CC1
Chieco-Bianchi, L; Forino, M; Majone, F; Saggioro, D; Turchetto, L1
Bartoli, S; Colacci, A; Da Via, C; Grilli, S; Perocco, P; Silingardi, P; Vaccari, M1
Coder, DM; Garrett, LR; McDougall, JK1
Brissette, JL; Dotto, GP; Gilula, NB; Kumar, NM1
Bonham, K; Bowden, GT; Krieg, P; Ostrowski, LE1
Cheng, SJ; Li, MX; Lu, FX1
Hsu, PL; Hsu, SM1
Austin, SJ; Beeman, DK; Lasley, JA; Mass, MJ; Schorschinsky, NS2
Afar, DE; Bell, JC; Braun, PE; Roder, J; Salzer, JL1
Datta, R; Kharbanda, S; Kufe, D; Nakamura, T; Sherman, ML1
Berkovic, D; Doenecke, D; Eibl, H; Hochhuth, C; Unger, C1
Dorkin, HL; Grubman, SA; Iannuzzi, MC; Jefferson, DM; Klinger, KW; Li, M; Marini, FC; Valentich, JD; Welsh, MJ1
Alitalo, K; Comoglio, PM; Di Renzo, MF; Koskinen, P; Lehtola, L; Lehväslaiho, H; Sistonen, L1
Fürstenberger, G; Krieg, P; Marks, F; Schnapke, R; Vogt, I1
Meadows, GG; Thrall, BD1
Faller, DV; Mundschau, LJ; Quiñones, MA; Rake, JB1
Hara, J; Inoue, M; Ishihara, S; Koizumi, S; Kurahashi, H; Murayama, N; Okamura, J; Tawa, A; Toyoda, Y; Yumura-Yagi, K1
el-Okda, MO; Hsu, PL; Hsu, SM; Xie, SS1
Carney, DH; Fenton, JW; Morris, DL; Nechay, P; Ward, JB; Whorton, EB1
Gélinas, C; Kumar, S; McDonnell, PC; Rabson, AB1
Colburn, NH; De Benedetti, F; Falk, L; Faltynek, CR; Oppenheim, JJ; Ruscetti, FW1
Bauer, G; Götschl, M; Höfler, P1
Embleton, MJ; Noy, RJ1
Das, UN1
Rieber, M; Rieber, MS1
Godwin, AK; Lieberman, MW1
Borner, C; Filipuzzi, I; Imber, R; Weinstein, IB1
Cuddy, MP; Rapp, UR; Reed, JC; Turner, BC; Yum, S1
Biozzi, G1
Carbone, A; Gusella, GL; Radzioch, D; Varesio, L1
Goppelt-Struebe, M; Hass, R; Rehfeldt, W1
Greenhalgh, DG; Hennings, H; Robinson, VA; Welty, DJ; Yuspa, SH1
Crawford, DR; Greenberger, JS1
Balmain, A; Burns, PA; Haddow, S; Jack, A; Neilson, F1
Mikalsen, SO; Rivedal, E; Sanner, T2
Chiu, R; Karin, M; Yang-Yen, HF1
Alitalo, K; Bravo, R; Koskinen, PJ; Lehtola, L; Lehväslaiho, H; Sistonen, L1
Greene, MI; Qian, XL; Wada, T1
Ishidate, M; Mizusawa, H; Sakai, A; Sasaki, K1
Fabbro, D; Imber, R1
Mason, SN; Weinberg, JB1
Borek, C; Merrill, AH; Ong, A; Stevens, VL; Wang, E1
Kennedy, AR; Su, LN; Toscano, WA1
Balcer-Kubiczek, EK; Harrison, GH5
Anderson, WB; Kiss, Z; Pettit, GR; Rapp, UR1
Furukawa, M; Hamada, T; Ishii, M; Kono, T; Mizuno, N; Taniguchi, S; Tanii, T; Yoshizato, K1
Kuroki, T; Nose, K; Saito, H1
Katoh, S; Matsuda, I; Matsumoto, R; Migita, M; Mita, S; Sonoda, E; Takatsu, K; Tominaga, A; Tsuchiya, H; Yamaguchi, N1
Hirayama, C; Hirayoshi, K; Nagata, K; Nakai, A; Ohtsuka, K1
Nori, M; Shawver, LK; Weber, MJ1
Belman, S; Bosland, MC; Estensen, RD; Savarese, K; Sellakumar, A1
Fialkow, PJ; Reddy, AL1
Han, KK; Wu, J; Zhu, DX; Zhu, JQ1
Datta, R; Imamura, K; Kufe, DW; Sherman, ML; Stone, RM1
Lin, MC; Wu, YY1
Bernard, HU; Chan, WK; Chong, T; Klock, G1
Collier, IE; Frisch, SM; Genrich, LT; Goldberg, GI; Martin, G; Reich, R1
Han, JW; Macara, IG; Sadowski, H; Young, DA1
Alitalo, K; Alitalo, R; Andersson, L; Hölttä, E; Partanen, J; Pertovaara, L; Sistonen, L1
Brennan, A; Estridge, JK; Katz, DR; Kemp, LM; Latchman, DS1
Flaegstad, T; Moens, U; Sundsfjord, A; Traavik, T1
Hsu, PL; Hsu, SM; Xie, SS1
Etscheid, BG; Jamieson, GA; Toscas, K; Villereal, ML1
Nebert, DW; Owens, RA1
Garcin, D; Jacquemont, B; Madjar, JJ; Massé, T1
Chambers, AF; Craig, AM; Denhardt, DT; Edwards, DR; Guo, XJ; Murphy, LC; Parfett, CL; Reid, RE; Waterhouse, P1
Burstein, DE; Lacal, JC; Pellicer, A; Thomson, TM; Trotta, RJ1
Ishidate, M; Mizusawa, H; Sasaki, K; Tanaka, N1
Boswell, HS; Burgess, GS; Gabig, TG; Harrington, MA; Inhorn, L; Nahreini, TS; Srivastava, A; Srour, EF1
Burns, FJ1
Facy, P; Hubert, J; Hubert, M; Monsigny, M; Seve, AP1
Arcuri, RA; De Souza, MH; Marques-Silva, VM; Rumjanek, VM; Teixeira, MC1
Kolman, A; Näslund, M; Osterman-Golkar, S1
Cardiff, RD; Kuo, A; Leder, A; Leder, P; Sinn, E1
Earp, HS; Grisham, JW; Raymond, VW1
Birnie, GD; Jamieson, T; Neill, R; Vass, JK1
Château, MT; Marti, J; Pacaud, M; Taimi, M1
Aronow, BJ; Fugman, DA; Jones, CL; Lieberman, MA; Witte, DP1
Inui, N; Semba, M2
Archer, LT; Bales, WD; Bass, RA; Bell, PB; Hemstreet, GP; Hurst, RE; Jones, PL; Rao, JY1
Chouroulinkov, I; Lasne, C; Lu, YP; Orfila, L; Ventura, L1
Heine, UI; Kenney, S; Rice, JM; Riggs, CW; Yamadori, I1
Chandra, A; Chandra, P; Gerber, T; Massa, T; Pfaffenholz, V; Schlatterer, B1
Bortner, DM; Ostrowski, MC; Owen, RD1
Billings, PC; Habres, JM; Kennedy, AR1
Baron, PL; Carchman, RA; Collins, JM; Koretz, MJ; Parker, GA; Tokarz, AS1
Crowcroft, NS; Parkinson, EK; Quigley, JP; Stanley, MA1
Parkinson, EK2
Albino, AP; Eisinger, M; Houghton, AN; Kantor, RR; Lee, JS; Old, LJ; Oliff, AI1
Jani, H; Knowles, MA1
Olson, SA; Shawver, LK; Weber, MJ; White, MK1
Kuratomi, Y; Kuwano, M; Masumi, S; Ono, M; Yasutake, C1
Alcorta, DA; Blenis, J; Erikson, RL; Kuo, CJ1
Cheng, CK; Krieg, TM; Mehrel, T; Roop, DR; Yuspa, SH1
Aldaz, CM; Conti, CJ1
Conklin, BR; Felder, CC; Ma, AL1
Buchou, T; Charollais, RH; Fagot, D; Mester, J1
Choi, JK; Shalloway, D; Yaciuk, P1
Cole, MD; Mango, SE; Schuler, GD; Steele, ME1
Aller, P; Rius, C1
Miller, DR; Morris, RJ; O'Connell, JF; Patskan, GP; Slaga, TJ; Tacker, K; Viaje, AV1
Athar, M; Bickers, DR; Lloyd, JR; Mukhtar, H1
Fujita, H; Kuzumaki, N; Oda, A; Ogiso, Y; Suzuki, H; Uchino, J1
Imler, JL; Wasylyk, B1
Cheng, SJ1
Bernstein, LR; Colburn, NH1
Ibaraki, T; Ito, Y; Satake, M; Yamaguchi, Y1
Bonfil, RD; Fridman, R; Harris, CC; Klein-Szanto, A; Momiki, S; Reddel, R; Reich, R1
Bonham, K; Bowden, GT; Cress, AE; Embry, T; Gibson, D; Jaffe, DR; Roberts, RA1
Steele, VE1
Dull, TJ; Honegger, AM; Riedel, H; Schlessinger, J; Ullrich, A1
Bowden, GT; Jaffe, DR1
Jain, AK; Nakamura, Y; Sano, M; Shimoi, K; Tomita, I1
Chan, TC1
Borowski, P; Harbers, M; Hilz, H; Kischel, T; Müller, K; Stabel, S1
Gilmour, SK; O'Brien, TG1
Hsiao, WL; Lopez, CA; Weinstein, IB1
Cooper, CS; Darling, J; Lantos, PL; Pilkington, GJ; Reeves, BR; Stratton, MR1
Dotto, GP; el-Fouly, MH; Nelson, C; Trosko, JE1
Birnbaum, MJ; Garcia de Herreros, A; Hiraki, Y1
Fujiki, H; Ikeda, I; Kitani, H; Nagao, M; Rapp, U; Sakai, R; Sugimura, T; Takaku, F1
Fiebig, H; Grunicke, H; Hofmann, J; Maly, K; Oberhuber, H; Posch, L; Uberall, F1
Barrett, JC; Gray, T; Nelson, K; Nettesheim, P; Tanaka, N1
Craig, AM; Denhardt, DT; Smith, JH1
Alitalo, K; Bos, TJ; Keski-Oja, J; Pertovaara, L; Sistonen, L; Vogt, PK1
Dugina, VB1
Elkind, MM; Han, A; Hill, CK2
Barni, S; Meloni, MA; Pippia, P; Sciola, L; Tilloca, G1
Collins, RD; Cousar, JB; Kinney, MC; Vogler, LB; Whitlock, J1
Earp, HS; Grisham, JW; Lee, DC; Raymond, VW1
Inoue, R; Kitani, T; Kuratsune, H; Machii, T; Nakamura, Y; Nishimori, Y; Tokumine, Y; Ueda, E; Waki, K1
Arita, I; Mitani, H; Sasaki, MS; Tachibana, A; Takebe, H; Tatsumi, K; Toyoda, M1
Sakai, A; Sato, M1
Colburn, NH; Kligman, D; Patel, J; Simek, SL1
Antony, M; Mehrotra, NK; Shukla, Y1
Colburn, NH; Gindhart, TD; Nakamura, Y; Seed, JL; Tomita, I; Winterstein, D1
Bailly, J; Bernard, BA; Darmon, M; Delescluse, C; Fürstenberger, G; Marks, F; Sorg, B1
Obom, KM; Pogo, BG1
Barber, JR; Sassone-Corsi, P; Verma, IM2
Cabot, MC; Cao, HT; Chabbott, H; Lebowitz, M; Welsh, CJ; Zhang, ZC1
Daniel, LW; Krebs, CR; Kucera, LS; Roddick, VL; Waite, M1
Ashmun, RA; Downing, JR; Rettenmier, CW; Roussel, MF; Sherr, CJ1
Bentley, KS; Fatteh, MV; Grisham, JW; Lee, LW; Smith, GJ1
Morgan, EH; Sorokin, LM; Yeoh, GC1
Chouroulinkov, I; Lasne, C; Lowy, R; Lu, YP1
Cohen, B; Druker, B; Kaplan, D; Keller, T; Mamon, H; Morgan, W; Piwnica-Worms, H; Roberts, TM; Schaffhausen, B; Whitman, M1
Dooley, TP; Hart, IR; Jones, NC; Wilson, RE1
Kaufman, DG; Nelson, KG; Siegfried, JM1
Lichti, U; Yuspa, SH1
Aujard, C; Lafarge-Frayssinet, C; Morel-Chany, E1
Delhanty, JD; Rider, SH1
Abernethy, DJ; Boreiko, CJ; Rickert, DE; Stedman, DB1
Aumailley, M; Chu, ML; Hatamochi, A; Krieg, T; Mauch, C; Timpl, R1
Carter, T; Chan, E; Greene, B; James, C1
Blaney, C; Finn, T; Lawlor, E; McCann, SR; Temperley, IJ; Whelan, A1
Fujinaga, K; Kato, H; Yamashita, T1
Colburn, NH; Gindhart, TD; Nakamura, Y1
Pelling, JC; Slaga, TJ1
Colburn, NH; Gindhart, TD; Hegamyer, GA; Lerman, MI1
Kensler, TW; Kozumbo, WJ; Trush, MA1
Gentry, LE; Purchio, AF; Shoyab, M1
Issinger, OG; Rance, AJ; Thönnes, M1
Fairbairn, S; Gilbert, R; Ojakian, G; Quigley, JP; Schwimmer, R1
Abe, E; Chida, K; Hashiba, H; Hosoi, J; Hosomi, J; Kuroki, T; Sasaki, K; Suda, T1
Chen, KY; Liu, AY1
Altman, A; Isakov, N1
Abe, E; Chida, K; Hashiba, H; Kamata, N; Kuroki, T; Sasaki, K; Suda, T1
Kanno, Y1
Garte, SJ1
Colburn, NH; Hegamyer, GA; Lerman, MI1
Angel, P; Herrlich, P; Lücke-Huhle, C; Pöting, A; Rahmsdorf, HJ1
Kraft, AS1
Buzhiyevskaya, TI; Lukash, LL; Shapiro, NI; Varshaver, NB1
Müller, R1
Bertram, JS; Martner, JE2
Kakunaga, T; Sagara, J; Yamada, KM1
Abe, E; Colburn, NH; Hosoi, J; Kuroki, T; Suda, T1
Bishop, JM; Klempnauer, KH; Moscovici, C; Moscovici, G; Snyder, M; Symonds, G1
Ono, T; Tanaka, K; Umeda, M2
Barrett, JC; Gilmer, TM; Jetten, AM1
Hiwasa, T; Sakiyama, S; Tanigawara, C1
Colburn, NH; Lerman, MI; Sakai, A; Yao, KT1
Clark, EJ; Frisch, SM; Werb, Z1
Inui, N; Ohkawa, Y; Saito, M; Tanaka, N1
Kennedy, AR; Symons, MC1
Poulin, L; Skalski, V; Wainberg, MA1
Gorbunova, LV; Raevskaia, GB; Shapiro, NI; Varshaver, NB1
Ashendel, CL; Taparowsky, EJ; Weyman, CM; Wolfson, M1
Callaham, MF; Huberman, E; Jones, CA1
Kakunaga, T; Kawamoto, T; Makino, K; Niwa, H; Orita, S; Sugiyama, H1
Huang, M; Kamata, N; Kuroki, T; Nose, K1
Colburn, NH; Gindhart, TD; Smith, BM2
Blumenson, L; Kulesz-Martin, M; Lisafeld, B1
Mehta, RG; Moon, RC1
Ernst, SM; Hixson, DC; Nairn, RS; Patskan, G; Pelling, JC; Rhode, SL; Slaga, TJ1
Hsiao, WL; Weinstein, IB; Wu, T1
Lockney, MW; Marvel, CC; Moskal, JR; Sweeley, CC; Trosko, JE1
Danner, MW; Marian, B1
Flier, JS; Lodish, HF; Mueckler, MM; Usher, P1
Benjamin, CW; Gorman, RR; Tarpley, WG1
Brown, CC; Chu, KC; Tan, WY; Tarone, RE1
Garland, JM1
Kitagawa, S; Miura, Y; Ohta, M; Saito, M; Takaku, F1
Colburn, NH; Nakamura, Y; Smith, BM; Wendel, EJ; Winterstein, D1
Ishidate, M; Mizusawa, H; Sasaki, K1
Bryan, GT; Reznikoff, CA; Verma, AK1
Colburn, NH; Gindhart, TD; Hegameyer, GA; Nakamura, Y; Smith, BM; Stevens, LA; West, MW1
Alitalo, K; Alitalo, R; Andersson, LC; Koskinen, P; Mäkelä, TP1
Horiuchi, T; Kusaba, T; Mayumi, T; Nagasawa, K1
Colburn, NH; Dion, LD; Gindhart, TD1
Horikoshi, J; Kaneko, M1
Baturay, NZ; Trombetta, LD1
Lichtman, MA; Segel, GB; Woodlock, TJ1
Gschwendt, M; Kittstein, W; Marks, F1
Colburn, NH; Dowjat, WK; Shimada, T; Smith, BM; Wendel, EJ1
Firestein, GS; Gruber, HE; Reifler, D; Richman, D1
Kennedy, AR; Umans, RS1
Mordan, LJ1
Hirokawa, M; Kudo, K; Miura, AB; Takahashi, T; Takatsu, H; Yoshida, K1
Bowden, GT; Gensler, HL; Moriguchi, S; Watson, RR1
Dugina, VB; Gelfand, IM; Svitkina, TM; Vasiliev, JM1
Bhoopalam, N; Drexler, HG; Gaedicke, G; Klein, M; Minowada, J1
Campisi, J; Dean, M; Levine, RA; Ran, W1
Baserga, R; Calabretta, B; Heintz, N; Kaczmarek, L; Kao, HT; Nevins, J1
Almendral, JM; Bravo, R; Húbsch, D; Macdonald-Bravo, H; Müller, R1
Colburn, NH; Dowjat, WK; Gindhart, TD; Lerman, MI; Shimada, T1
Brown, MA; Falco, J; Ihle, JN; Paul, WE; Pierce, JH; Watson, CJ1
Castagnola, J; MacLeod, C; Mendelsohn, J; Sunada, H; Taetle, R1
Kodama, M1
Brankow, DW; Herschman, HR2
Colburn, NH; Smith, BM1
Djurhuus, R; Laerum, OD; Lillehaug, JR1
Bian, SG; Wang, ZC; Yan, WW1
Bjerkvig, R; Lillehaug, JR; Male, R1
Baldwin, JK; Fischer, SM; Jasheway, DW; Patrick, KE1
Brodskaia, RM1
Chouroulinkov, I; Lasne, C; Lu, YP1
Kokunai, T; Korosue, K; Matsumoto, S; Tamaki, N1
Kuroki, T1
Cerutti, PA; Kozumbo, WJ1
Abernethy, DJ; Boreiko, CJ; Sanchez, JH1
Angel, P; Herrlich, P; Mallick, U; Pöting, A; Rahmsdorf, HJ; Schorpp, M1
Haarr, L; Kleppe, K; Lillehaug, JR1
Inui, N; Ohkawa, Y; Saito, M1
Henschler, D; Hildebrandt, AG; Kahl, R; Potenberg, J; Schiffmann, D1
Best, JB; Hall, F; Morita, M2
Abernethy, DJ; Boreiko, CJ; Stedman, DB1
Chouroulinkov, I; Sala, M; Tran, PL1
Carter, TH; Zelinsky-Papez, K; Zimmerman, JA1
Chouroulinkov, I; Lasne, C; Lu, YP; Sala, M1
Aguelon-Pegouries, AM; Enomoto, T; Furstenberger, G; Marks, F; Martel, N; Yamasaki, H1
Elkind, MM; Hill, CK1
Brankow, D; Herschman, HR1
Mitchell, RL; Schreiber, RD; Verma, IM; Zokas, L1
Arthur, DC; Kersey, JH; Korsmeyer, SJ; Parkin, JL; Stong, RC1
Gschwendt, M; Horn, F; Kittstein, W; Marks, F1
Hennings, H; Yuspa, SH1
Fürstenberger, G; Kinzel, V; Marks, F; Schwarz, M1
Huberman, E; Jones, CA1
Bravo, R; Curran, T; Müller, R1
Aarsaether, N; Berge, RK; Lillehaug, JR; Male, R1
Borek, C; Cleaver, JE1
Yamasaki, H1
Enomoto, T; Kakunaga, T; Kanno, Y; Shiba, Y; Yamasaki, H1
Wolf, G; Zerlauth, G1
Johnson, J; Munker, R; Petersmann, I; Riethmüller, G; Schmoeckel, C; Ziegler-Heitbrock, HW1
Revoltella, RP; Sambuy, Y; Spagnoli, LG; Vigneti, E1
Clark, EP; Stossel, TP; Weitberg, AB; Weitzman, SA1
Buzhievskaia, TI; Bykorez, AI; Kononenko, LI; Lukash, LL; Shapiro, NI1
Barrett, JC; Gray, TE; Nettesheim, P1
Beeman, DK; Leavitt, SA; Mass, MJ; Siegfried, JM1
Boreiko, CJ2
Barrett, JC1
Abernethy, DJ; Boreiko, CJ; Greenlee, WF; Huband, JC1
Enomoto, T; Rivedal, E; Sanner, T; Yamasaki, H1
Gibson, NW; Hartley, JA; Yuspa, SH; Zwelling, LA1
Higgins, PJ1
Buzhievskaia, TI; Lukash, LL; Shapiro, NI; Varshaver, NB1
Barrett, JC; Gray, T; Nettesheim, P1
Barrett, JC; Nettesheim, P1
Abernethy, DJ; Boreiko, CJ; Huband, JC1
De Luca, LM1
Bruce, SA; Horng, CB; Ts'o, PO1

Reviews

43 review(s) available for tetradecanoylphorbol acetate and Cell Transformation, Neoplastic

ArticleYear
Molecular mechanisms of tumor promotion and multistage carcinogenesis.
    Princess Takamatsu symposia, 1983, Volume: 14

    Topics: Adenosine Triphosphate; Animals; Base Sequence; Caenorhabditis elegans Proteins; Carrier Proteins; Cell Transformation, Neoplastic; ErbB Receptors; Humans; Lyngbya Toxins; Molecular Conformation; Neoplasms; Oncogenes; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Kinase C; Protein Kinases; Receptors, Cell Surface; Receptors, Drug; Receptors, Immunologic; Structure-Activity Relationship; Tetradecanoylphorbol Acetate

1983
Interactions between initiating chemical carcinogens, tumor promoters, and adenovirus in cell transformation.
    Teratogenesis, carcinogenesis, and mutagenesis, 1980, Volume: 1, Issue:3

    Topics: Adenoviridae; Animals; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Clone Cells; DNA; Embryo, Mammalian; Female; Pregnancy; Rats; Tetradecanoylphorbol Acetate

1980
Cell culture systems for studying multifactor interactions in carcinogenesis.
    Developments in toxicology and environmental science, 1980, Volume: 8

    Topics: Animals; Carcinogens; Cell Differentiation; Cell Membrane; Cell Transformation, Neoplastic; Cells, Cultured; Cocarcinogenesis; DNA; Drug Evaluation, Preclinical; ErbB Receptors; Humans; Models, Biological; Oncogenic Viruses; Phospholipids; Receptors, Cell Surface; Tetradecanoylphorbol Acetate

1980
Epidermal growth factor receptors interact with transforming growth factors produced by certain human tumor cells and are distinct from specific membrane receptors for phorbol and ingenol esters.
    Carcinogenesis; a comprehensive survey, 1982, Volume: 7

    Topics: Animals; Caenorhabditis elegans Proteins; Carcinogens; Carrier Proteins; Cell Adhesion; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cocarcinogenesis; ErbB Receptors; Humans; Neoplasms; Peptides; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Transforming Growth Factors

1982
Prostaglandins and cancer: a review of tumor initiation through tumor metastasis.
    Prostaglandins, 1981, Volume: 21, Issue:5

    Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Cell Differentiation; Cell Division; Cell Transformation, Neoplastic; Cyclooxygenase Inhibitors; DNA; Epoprostenol; Female; Hematopoietic Stem Cells; Humans; Kidney; Male; Mutagens; Neoplasm Metastasis; Neoplasms; Oxidation-Reduction; Prostaglandins; Prostaglandins D; Prostaglandins E; Prostaglandins F; Skin; Tetradecanoylphorbol Acetate; Thromboxane A2

1981
[Effect of tumor promotor on neoplastic cell transformation].
    Nihon rinsho. Japanese journal of clinical medicine, 1983, Volume: 41, Issue:2

    Topics: Animals; Carcinogens; Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; Guinea Pigs; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Macrophages; Mice; Phorbols; T-Lymphocytes; Tetradecanoylphorbol Acetate

1983
Membrane and genetic events in tumor promotion: studies with promoter resistant variants of JB6 cells.
    Princess Takamatsu symposia, 1983, Volume: 14

    Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Clone Cells; Drug Resistance; Epidermis; Gangliosides; Genes; Mice; Mice, Inbred BALB C; Oxygen; Phenotype; Superoxide Dismutase; Tetradecanoylphorbol Acetate

1983
Critical biochemical and regulatory events in malignant transformation in vitro.
    Princess Takamatsu symposia, 1983, Volume: 14

    Topics: Animals; Benzamides; Cell Transformation, Neoplastic; Cricetinae; DNA Repair; Humans; In Vitro Techniques; Mice; Mutation; Neoplasms; Poly Adenosine Diphosphate Ribose; Sister Chromatid Exchange; Tetradecanoylphorbol Acetate; Thyroid Hormones

1983
Molecular and cellular basis for tumor promotion in mouse skin.
    Princess Takamatsu symposia, 1983, Volume: 14

    Topics: Animals; Calcium; Cell Division; Cell Transformation, Neoplastic; Mice; Oncogenes; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate

1983
Cellular and biochemical changes during multistage skin tumor promotion.
    Princess Takamatsu symposia, 1983, Volume: 14

    Topics: Animals; Antioxidants; Cell Transformation, Neoplastic; Free Radicals; Gene Amplification; Humans; Mice; Ornithine Decarboxylase; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate

1983
Genetic predisposition to cancer in man: in vitro studies.
    International review of cytology, 1982, Volume: 77

    Topics: Adenoma; Antigens, Neoplasm; Carcinogens; Cell Division; Cell Membrane; Cell Transformation, Neoplastic; Cells, Cultured; Cholesterol; Colonic Neoplasms; Cytoskeleton; Disease Susceptibility; Fibroblasts; Fibronectins; Genes, Dominant; Humans; Mitochondria; Mutation; Neoplasms; Rectal Neoplasms; Tetradecanoylphorbol Acetate

1982
Potent tumor promoters other than phorbol ester and their significance.
    Gan, 1982, Volume: 73, Issue:4

    Topics: Alkaloids; Animals; Cell Adhesion; Cell Aggregation; Cell Transformation, Neoplastic; Enzyme Induction; Humans; Isomerism; Lactones; Lyngbya Toxins; Marine Toxins; Mice; Mollusk Venoms; Neoplasms; Ornithine Decarboxylase; Phorbols; Tetradecanoylphorbol Acetate

1982
In vitro studies on the mode of action of the phorbol esters, potent tumor promoters: part 1.
    Critical reviews in toxicology, 1980, Volume: 8, Issue:2

    Topics: Animals; Blood Cells; Cell Membrane; Cell Transformation, Neoplastic; Cells, Cultured; Chick Embryo; Hormones; Humans; Mice; Microtubules; Mitosis; Nucleotides, Cyclic; Phorbol Esters; Phorbols; Phospholipids; Polyamines; Tetradecanoylphorbol Acetate

1980
In vitro studies on the mode of action of the phorbol esters, potent tumor promoters, part 2.
    Critical reviews in toxicology, 1981, Volume: 8, Issue:3

    Topics: Animals; Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; Clone Cells; DNA Repair; Models, Biological; Mutagens; Mutation; Neoplasms, Experimental; Phorbol Esters; Phorbols; Structure-Activity Relationship; Tetradecanoylphorbol Acetate

1981
Phenotypic and chromosomal alterations in cell cultures as indicators of tumor-promoting activity.
    Carcinogenesis; a comprehensive survey, 1982, Volume: 7

    Topics: Animals; Carcinogens; Cell Adhesion; Cell Communication; Cell Differentiation; Cell Division; Cell Membrane; Cell Transformation, Neoplastic; Cells, Cultured; Chromosome Aberrations; Cocarcinogenesis; Fibronectins; Humans; Neoplasms, Experimental; Ornithine Decarboxylase; Plasminogen Activators; Tetradecanoylphorbol Acetate; Tretinoin

1982
Inhibition of cell-cell communication by tumor promoters.
    Carcinogenesis; a comprehensive survey, 1982, Volume: 7

    Topics: Animals; Biological Assay; Calcium; Carcinogens; Cell Communication; Cell Differentiation; Cell Division; Cell Line; Cell Membrane; Cell Transformation, Neoplastic; Cocarcinogenesis; Contact Inhibition; Gene Expression Regulation; Intercellular Junctions; Models, Biological; Mutation; Receptors, Drug; Tetradecanoylphorbol Acetate

1982
International Commission for Protection against Environmental Mutagens and Carcinogens ICPEMC working paper 2/8: An evaluation of assay procedures for detection of tumor promotors.
    Mutation research, 1982, Volume: 98, Issue:3

    Topics: Animals; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cocarcinogenesis; Mice; Mutagenicity Tests; Rats; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate

1982
Effect of conjugated linoleic acid on carcinogenesis.
    Advances in experimental medicine and biology, 1994, Volume: 364

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antimutagenic Agents; Cell Transformation, Neoplastic; Female; Gastrointestinal Neoplasms; Linoleic Acids; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred ICR; Rats; Rats, Inbred F344; Signal Transduction; Tetradecanoylphorbol Acetate

1994
Positive and negative growth regulation in melanoma: growth factors, intracellular signalling, and the cell cycle.
    Cancer treatment and research, 1993, Volume: 65

    Topics: Animals; Cell Cycle; Cell Transformation, Neoplastic; Fibroblast Growth Factor 2; Growth Substances; Humans; Melanocytes; Melanoma; Protein Kinase C; Protein Kinases; Signal Transduction; Tetradecanoylphorbol Acetate

1993
[Terpenoids and steroids from several euphorbiaceae and pinaceae plants].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1999, Volume: 119, Issue:5

    Topics: Animals; Cell Transformation, Neoplastic; Euphorbiaceae; HeLa Cells; Humans; Mice; Molecular Conformation; Steroids; Terpenes; Tetradecanoylphorbol Acetate; Topoisomerase I Inhibitors; Trees

1999
Activator protein 1 (AP-1)- and nuclear factor kappaB (NF-kappaB)-dependent transcriptional events in carcinogenesis.
    Free radical biology & medicine, 2000, May-01, Volume: 28, Issue:9

    Topics: Animals; Apoptosis Regulatory Proteins; Carcinogens; Cell Transformation, Neoplastic; Clone Cells; Epidermal Cells; Epidermal Growth Factor; Epidermis; Gene Expression Regulation, Neoplastic; Humans; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neoplasm Proteins; NF-kappa B; Oxidation-Reduction; Oxidative Stress; Phenotype; Protein Biosynthesis; Proteins; Reactive Oxygen Species; RNA-Binding Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription, Genetic; Transcriptional Activation; Transfection; Tumor Necrosis Factor-alpha

2000
Signal transduction and white cell maturation via extracellular ATP and the P2Y11 receptor.
    Immunology and cell biology, 2000, Volume: 78, Issue:4

    Topics: Actins; Adenosine Triphosphate; Blotting, Northern; Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; Flow Cytometry; HL-60 Cells; Humans; Leukocytes; N-Formylmethionine Leucyl-Phenylalanine; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; Receptors, Purinergic P2; RNA, Messenger; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate

2000
[The proteasome and malignant hemopathies].
    Morphologie : bulletin de l'Association des anatomistes, 2000, Volume: 84, Issue:265

    Topics: Biomarkers, Tumor; Cell Differentiation; Cell Membrane; Cell Nucleus; Cell Transformation, Neoplastic; Cysteine Endopeptidases; Cytoplasm; Enzyme-Linked Immunosorbent Assay; Hematologic Neoplasms; Humans; L-Lactate Dehydrogenase; Leukemia-Lymphoma, Adult T-Cell; Multienzyme Complexes; Neoplasm Proteins; Neoplasms; Proteasome Endopeptidase Complex; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured; U937 Cells; Vitamin D

2000
Synergistic effect of tumor virus transformation and tumor promoter treatment on the production of plasminogen activator by chick embryo fibroblasts.
    Cancer research, 1978, Volume: 38, Issue:12

    Topics: Avian Sarcoma Viruses; Cell Transformation, Neoplastic; Cells, Cultured; Models, Biological; Phorbols; Plasminogen Activators; Tetradecanoylphorbol Acetate

1978
Action of phorbol esters in cell culture: mimicry of transformation, altered differentiation, and effects on cell membranes.
    Journal of supramolecular structure, 1979, Volume: 12, Issue:2

    Topics: Adenoviruses, Human; Animals; Arachidonic Acids; Cell Differentiation; Cell Membrane; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Female; HeLa Cells; Humans; Kinetics; Membrane Fluidity; Membrane Lipids; Mice; Phorbols; Prostaglandins; Rats; Tetradecanoylphorbol Acetate

1979
Interaction and distinction of genotoxic and non-genotoxic events in carcinogenesis.
    Toxicology letters, 1992, Volume: 64-65 Spec No

    Topics: 3T3 Cells; 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Humans; Mice; Mutagens; Neoplasms; Risk Factors; Tetradecanoylphorbol Acetate

1992
Differential gene expression during tumor promotion and progression in the mouse skin model.
    Basic life sciences, 1991, Volume: 57

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Actins; Animals; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cocarcinogenesis; DNA; Gene Expression Regulation, Neoplastic; Matrix Metalloproteinase 3; Metalloendopeptidases; Methylnitronitrosoguanidine; Mice; Neoplasm Metastasis; Neoplasm Proteins; Neoplasms, Multiple Primary; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Ubiquitins

1991
Nonmutagenic mechanisms in carcinogenesis: role of protein kinase C in signal transduction and growth control.
    Environmental health perspectives, 1991, Volume: 93

    Topics: Animals; Bacteria; Cell Line, Transformed; Cell Transformation, Neoplastic; Cocarcinogenesis; Colon; Colonic Neoplasms; Diglycerides; Enzyme Activation; Enzyme Induction; Fibroblasts; Gene Expression Regulation, Neoplastic; Humans; Isoenzymes; Mice; Protein Kinase C; Proto-Oncogenes; Signal Transduction; Tetradecanoylphorbol Acetate

1991
Arachidonic acid as a mediator of some of the actions of phorbolmyristate acetate, a tumor promoter and inducer of differentiation.
    Prostaglandins, leukotrienes, and essential fatty acids, 1991, Volume: 42, Issue:4

    Topics: Animals; Arachidonic Acids; Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; Humans; Oncogenes; Tetradecanoylphorbol Acetate

1991
Promotion and progression in carcinogenesis.
    Progress in clinical and biological research, 1990, Volume: 340D

    Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Disease Models, Animal; Mice; Papilloma; Rats; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors

1990
The conversion stage of skin carcinogenesis.
    Carcinogenesis, 1990, Volume: 11, Issue:12

    Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Mice; Models, Biological; Papilloma; Phorbol Esters; Precancerous Conditions; Skin Neoplasms; Tetradecanoylphorbol Acetate

1990
Defective responses of transformed keratinocytes to terminal differentiation stimuli. Their role in epidermal tumour promotion by phorbol esters and by deep skin wounding.
    British journal of cancer, 1985, Volume: 52, Issue:4

    Topics: Animals; Carcinogens; Cell Differentiation; Cell Transformation, Neoplastic; Epidermis; In Vitro Techniques; Keratins; Mice; Mitosis; Oncogenes; Papilloma; Peptides; Phenotype; Phorbols; Protein Kinase C; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transforming Growth Factors

1985
The premalignant nature of mouse skin papillomas: histopathologic, cytogenetic, and biochemical evidence.
    Carcinogenesis; a comprehensive survey, 1989, Volume: 11

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biomarkers, Tumor; Cell Transformation, Neoplastic; Chromosome Aberrations; Chromosome Disorders; Karyotyping; Keratins; Mice; Papilloma; Precancerous Conditions; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors

1989
Investigations of multistage carcinogenesis: applications of in vitro-in vivo studies.
    Carcinogenesis; a comprehensive survey, 1989, Volume: 11

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Differentiation; Cell Line, Transformed; Cell Transformation, Neoplastic; Cells, Cultured; Methylnitronitrosoguanidine; Mice; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1989
AP1, a composite transcription factor implicated in abnormal growth control.
    Progress in growth factor research, 1989, Volume: 1, Issue:2

    Topics: Animals; Cell Division; Cell Transformation, Neoplastic; DNA-Binding Proteins; Humans; Oncogenes; Proto-Oncogene Proteins c-jun; Tetradecanoylphorbol Acetate; Transcription Factors

1989
Cellular mechanisms for tumor promotion and enhancement.
    Carcinogenesis; a comprehensive survey, 1985, Volume: 8

    Topics: Animals; Cell Transformation, Neoplastic; Cocarcinogenesis; ErbB Receptors; Humans; Kidney Neoplasms; Liver Neoplasms; Oncogenes; Protein Kinase C; Protein Kinases; Receptors, Cell Surface; Skin Neoplasms; Tetradecanoylphorbol Acetate

1985
Modulation of cell communication and carcinogenesis.
    The Japanese journal of physiology, 1985, Volume: 35, Issue:5

    Topics: Animals; Antigens, Surface; Calcium; Carcinogens; Carrier Proteins; Cell Adhesion Molecules; Cell Communication; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cyclic AMP; Diterpenes; Humans; Intercellular Junctions; Mice; Mice, Inbred BALB C; Permeability; Phorbol Esters; Phospholipids; Protein Kinases; Sodium-Hydrogen Exchangers; Sodium-Potassium-Exchanging ATPase; Terpenes; Tetradecanoylphorbol Acetate

1985
Cellular and viral fos genes: structure, regulation of expression and biological properties of their encoded products.
    Biochimica et biophysica acta, 1986, Volume: 823, Issue:3

    Topics: Amino Acid Sequence; Animals; Base Sequence; Bone Neoplasms; Cell Differentiation; Cell Division; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Cell Transformation, Viral; Fibroblasts; Gene Expression Regulation; Gene Products, gag; Hematopoiesis; Humans; Leukemia, Myeloid, Acute; Male; Mice; Oncogenes; Osteosarcoma; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogenes; Rats; Retroviridae Proteins; Sarcoma Viruses, Murine; Teratoma; Tetradecanoylphorbol Acetate

1986
Molecular mechanisms of induction of transcription of beta-actin gene by tumour promoters and serum factors.
    IARC scientific publications, 1988, Issue:92

    Topics: Actins; Animals; Carcinogens; Cell Transformation, Neoplastic; Gene Expression Regulation; Mice; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transforming Growth Factors

1988
The origins of human cancer: molecular mechanisms of carcinogenesis and their implications for cancer prevention and treatment--twenty-seventh G.H.A. Clowes memorial award lecture.
    Cancer research, 1988, Aug-01, Volume: 48, Issue:15

    Topics: Carcinogens; Cell Transformation, Neoplastic; DNA; Environmental Exposure; Gene Amplification; Humans; Models, Biological; Neoplasms; Oncogenes; Polycyclic Compounds; Protein Kinase C; Tetradecanoylphorbol Acetate

1988
[Biophysics of the neoplastic process].
    Nihon rinsho. Japanese journal of clinical medicine, 1986, Volume: 44, Issue:2

    Topics: Animals; Carcinogens; Carcinogens, Environmental; Cell Transformation, Neoplastic; Colonic Neoplasms; DNA; Free Radicals; Humans; Neoplasms, Experimental; Peptide Chain Termination, Translational; Smoking; Tetradecanoylphorbol Acetate

1986
Control of cell differentiation and cell transformation in vitro by phorbol 12-myristate 13-acetate and 1 alpha,25-dihydroxyvitamin D3.
    Carcinogenesis; a comprehensive survey, 1985, Volume: 10

    Topics: Animals; Calcitriol; Carcinogens; Cell Differentiation; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Esterases; Humans; Lyngbya Toxins; Macrophages; Muramidase; Phorbols; Tetradecanoylphorbol Acetate

1985
Transient induction of c-fos and c-myc in an immediate consequence of growth factor stimulation.
    Cancer surveys, 1985, Volume: 4, Issue:4

    Topics: Animals; Blood; Calcimycin; Cell Line; Cell Transformation, Neoplastic; Colony-Stimulating Factors; Gene Expression Regulation; Growth Substances; Humans; Leukemia, Myeloid, Acute; Macrophages; Proto-Oncogenes; RNA, Messenger; Tetradecanoylphorbol Acetate

1985

Other Studies

891 other study(ies) available for tetradecanoylphorbol acetate and Cell Transformation, Neoplastic

ArticleYear
Nfe2l2 Regulates Metabolic Rewiring and Epigenetic Reprogramming in Mediating Cancer Protective Effect by Fucoxanthin.
    The AAPS journal, 2022, 01-18, Volume: 24, Issue:1

    Topics: Animals; Antioxidants; Cell Line; Cell Transformation, Neoplastic; Epigenesis, Genetic; Gene Expression Regulation; Gene Knockdown Techniques; Mice; NF-E2-Related Factor 2; Oxidation-Reduction; Reactive Oxygen Species; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Xanthophylls

2022
Gene Expression over Time during Cell Transformation Due to Non-Genotoxic Carcinogen Treatment of Bhas 42 Cells.
    International journal of molecular sciences, 2022, Mar-16, Volume: 23, Issue:6

    Topics: Animals; BALB 3T3 Cells; Butylated Hydroxyanisole; Carcinogenicity Tests; Carcinogens; Cell Transformation, Neoplastic; Gene Expression; Mice; Tetradecanoylphorbol Acetate

2022
DNA Methylome and Transcriptome Study of Triterpenoid CDDO in TPA-Mediated Skin Carcinogenesis Model.
    The AAPS journal, 2022, 11-02, Volume: 24, Issue:6

    Topics: Cell Transformation, Neoplastic; Epigenome; Humans; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcriptome; Triterpenes; Ultraviolet Rays

2022
Keratinocyte Regnase-1, a Downregulator of Skin Inflammation, Contributes to Protection against Tumor Promotion by Limiting Cyclooxygenase-2 Expression.
    The Journal of investigative dermatology, 2023, Volume: 143, Issue:5

    Topics: Acetates; Animals; Carcinogenesis; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cyclooxygenase 2; Dermatitis; Humans; Inflammation; Keratinocytes; Lithostathine; Mice; RNA, Messenger; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate

2023
Can a 12-gene expression signature predict the cell transforming potential of tumor promoting agents in Bhas 42 cells?
    Toxicology letters, 2023, Nov-01, Volume: 389

    Topics: Animals; BALB 3T3 Cells; Butylated Hydroxyanisole; Carcinogenicity Tests; Carcinogens; Cell Transformation, Neoplastic; Cholic Acid; Mice; Quercetin; Reproducibility of Results; Tetradecanoylphorbol Acetate; Transcriptome

2023
Triterpenoid corosolic acid modulates global CpG methylation and transcriptome of tumor promotor TPA induced mouse epidermal JB6 P+ cells.
    Chemico-biological interactions, 2020, Apr-25, Volume: 321

    Topics: Animals; Carcinogens; Cell Line; Cell Survival; Cell Transformation, Neoplastic; CpG Islands; DNA Methylation; Epidermal Cells; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Mice; Phytochemicals; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcriptome; Triterpenes

2020
Integrin α3β1 Is a Key Regulator of Several Protumorigenic Pathways during Skin Carcinogenesis.
    The Journal of investigative dermatology, 2021, Volume: 141, Issue:4

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Adhesion; Cell Adhesion Molecules; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Epidermis; Humans; Integrin alpha3beta1; Kalinin; Keratinocytes; Mice; Neoplasms, Experimental; Signal Transduction; Skin Neoplasms; Spheroids, Cellular; Tetradecanoylphorbol Acetate; Tetraspanin 24

2021
12-O-Tetradecanoylphorbol-13-acetate (TPA) is anti-tumorigenic in liver cancer cells via inhibiting YAP through AMOT.
    Scientific reports, 2017, 03-21, Volume: 7

    Topics: Angiomotins; Animals; Antineoplastic Agents; Caspase 3; Caspase 7; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Disease Models, Animal; Gene Expression; Heterografts; Humans; Intercellular Signaling Peptides and Proteins; Liver Neoplasms; Membrane Proteins; Mice; Microfilament Proteins; Nuclear Proteins; Phenotype; Protein Transport; Tetradecanoylphorbol Acetate; Transcription Factors

2017
Targeted disruption of TC-PTP in the proliferative compartment augments STAT3 and AKT signaling and skin tumor development.
    Scientific reports, 2017, 03-21, Volume: 7

    Topics: Alleles; Animals; Apoptosis; Cell Proliferation; Cell Transformation, Neoplastic; Disease Models, Animal; Epidermis; Gene Knockout Techniques; Gene Targeting; Hyperplasia; Keratinocytes; Mice; Mice, Knockout; Organ Specificity; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 2; Proto-Oncogene Proteins c-akt; Signal Transduction; Skin Neoplasms; STAT3 Transcription Factor; Tetradecanoylphorbol Acetate

2017
E1a is an exogenous in vivo tumour suppressor.
    Cancer letters, 2017, 07-28, Volume: 399

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenovirus E1A Proteins; Animals; Cell Proliferation; Cell Transformation, Neoplastic; Female; HCT116 Cells; Humans; Melanoma, Experimental; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Nude; Mice, Transgenic; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Transfection; Tumor Burden; Tumor Suppressor Proteins

2017
Red Ginseng Oil Inhibits TPA-Induced Transformation of Skin Epidermal JB6 Cells.
    Journal of medicinal food, 2018, Volume: 21, Issue:4

    Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Cell Line; Cell Transformation, Neoplastic; Cyclins; Cyclooxygenase 2; Epidermis; Extracellular Signal-Regulated MAP Kinases; Glycogen Synthase Kinases; Heme Oxygenase-1; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Mice; NF-E2-Related Factor 2; NF-kappa B; Panax; Plant Oils; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factor AP-1

2018
Lead facilitates foci formation in a Balb/c-3T3 two-step cell transformation model: role of Ape1 function.
    Environmental science and pollution research international, 2018, Volume: 25, Issue:12

    Topics: Animals; BALB 3T3 Cells; Carcinogens, Environmental; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Comet Assay; DNA Damage; DNA-(Apurinic or Apyrimidinic Site) Lyase; Gene Expression; Humans; Lead; Methylnitronitrosoguanidine; Mice; Models, Biological; Tetradecanoylphorbol Acetate

2018
Fucoxanthin Elicits Epigenetic Modifications, Nrf2 Activation and Blocking Transformation in Mouse Skin JB6 P+ Cells.
    The AAPS journal, 2018, 02-20, Volume: 20, Issue:2

    Topics: Animals; Antioxidant Response Elements; Cell Transformation, Neoplastic; CpG Islands; DNA Demethylation; Epidermal Cells; Epigenesis, Genetic; Gene Knockdown Techniques; Hep G2 Cells; Humans; Mice; NF-E2-Related Factor 2; RNA, Small Interfering; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Xanthophylls

2018
Multicolour lineage tracing reveals clonal dynamics of squamous carcinoma evolution from initiation to metastasis.
    Nature cell biology, 2018, Volume: 20, Issue:6

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cell Lineage; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Clonal Evolution; Epithelial Cells; Female; Gene Expression Regulation, Neoplastic; Genes, ras; Genetic Predisposition to Disease; Male; Mice, Transgenic; Mutation; Neoplasms, Experimental; Phenotype; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Tumor Burden

2018
TRP63/TP63 loss accelerates skin tumorigenesis through activation of Wnt/β-catenin signaling.
    Journal of dermatological science, 2018, Volume: 91, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cell Differentiation; Cell Line; Cell Proliferation; Cell Transformation, Neoplastic; Gene Expression Regulation, Neoplastic; Genetic Predisposition to Disease; Humans; Mice, Knockout; Mice, Nude; Phosphoproteins; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Trans-Activators; Transcription Factors; Tumor Burden; Tumor Suppressor Proteins; Wnt Signaling Pathway

2018
Xiao Tan He Wei Decoction reverses MNNG-induced precancerous lesions of gastric carcinoma in vivo and vitro: Regulation of apoptosis through NF-κB pathway.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 108

    Topics: Animals; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Disease Models, Animal; Drugs, Chinese Herbal; Epithelial-Mesenchymal Transition; Humans; Hyperplasia; Methylnitronitrosoguanidine; NF-kappa B; Precancerous Conditions; Rats, Wistar; Stomach Neoplasms; Tetradecanoylphorbol Acetate

2018
C/EBPβ deletion in oncogenic Ras skin tumors is a synthetic lethal event.
    Cell death & disease, 2018, 10-15, Volume: 9, Issue:11

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; CCAAT-Enhancer-Binding Protein-beta; Cell Differentiation; Cell Transformation, Neoplastic; Gene Expression Regulation, Neoplastic; Genes, Lethal; Keratinocytes; Mice; Mice, Knockout; ras Proteins; Receptors, Death Domain; Signal Transduction; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53

2018
Bone marrow-derived epithelial cells and hair follicle stem cells contribute to development of chronic cutaneous neoplasms.
    Nature communications, 2018, 12-13, Volume: 9, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bone Marrow Cells; Bone Marrow Transplantation; Bone Morphogenetic Protein 5; Cell Movement; Cell Plasticity; Cell Transformation, Neoplastic; Coculture Techniques; Epithelial Cells; Female; Hair Follicle; HMGB1 Protein; Keratinocytes; Keratins; Male; Mice; Mice, Inbred C57BL; Neoplasm Invasiveness; Papilloma; Skin Neoplasms; Stem Cells; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

2018
[Role of clock proteins in skin carcinogenesis in 14-month-old SHR mice maintained under disrupted light regimen].
    Voprosy onkologii, 2016, Volume: 62, Issue:5

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; ARNTL Transcription Factors; Cell Transformation, Neoplastic; CLOCK Proteins; Cryptochromes; Gene Expression Regulation, Neoplastic; Lighting; Male; Mice; Neoplasm Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate

2016
CpG methyl-seq and RNA-seq epigenomic and transcriptomic studies on the preventive effects of Moringa isothiocyanate in mouse epidermal JB6 cells induced by the tumor promoter TPA.
    The Journal of nutritional biochemistry, 2019, Volume: 68

    Topics: Animals; Anticarcinogenic Agents; Carcinogens; Cell Line; Cell Transformation, Neoplastic; CpG Islands; DNA Methylation; Epidermal Cells; Epigenome; Isothiocyanates; Mice; Moringa; Sequence Analysis, RNA; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate

2019
Altered prostanoid signaling contributes to increased skin tumorigenesis in Tpl2 knockout mice.
    PloS one, 2013, Volume: 8, Issue:2

    Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Female; Gene Deletion; Gene Expression Regulation, Neoplastic; Keratinocytes; Male; MAP Kinase Kinase Kinases; Mice; Mice, Inbred C57BL; Prostaglandins; Proto-Oncogene Proteins; Receptors, Prostaglandin; Signal Transduction; Skin; Tetradecanoylphorbol Acetate

2013
Dysregulation of pathways involved in the processing of cancer and microenvironment information in MCA + TPA transformed C3H/10T1/2 cells.
    In vitro cellular & developmental biology. Animal, 2013, Volume: 49, Issue:4

    Topics: Animals; Carcinogens; Cell Line, Transformed; Cell Transformation, Neoplastic; Methylcholanthrene; Mice; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Microenvironment

2013
Mule/Huwe1/Arf-BP1 suppresses Ras-driven tumorigenesis by preventing c-Myc/Miz1-mediated down-regulation of p21 and p15.
    Genes & development, 2013, May-15, Volume: 27, Issue:10

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p15; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p21; Down-Regulation; Female; Genes, ras; Keratinocytes; Male; Mice; Mice, Knockout; Nuclear Proteins; Oncogene Protein p21(ras); Protein Inhibitors of Activated STAT; Proto-Oncogene Proteins c-myc; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Ubiquitin-Protein Ligases

2013
Modulatory effects of Azadirachta indica leaf extract on cutaneous and hepatic biochemical status during promotion phase of DMBA/TPA-induced skin tumorigenesis in mice.
    Indian journal of biochemistry & biophysics, 2013, Volume: 50, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Antioxidants; Azadirachta; Cell Transformation, Neoplastic; Cytochrome P-450 Enzyme System; Cytochromes b5; Gene Expression Regulation, Neoplastic; Glutathione Transferase; Lipid Peroxidation; Liver; Male; Mice; Micronucleus Tests; Neoplasms, Experimental; Phytotherapy; Plant Extracts; Plant Leaves; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Xenobiotics

2013
Fermented Prunus mume with probiotics inhibits 7,12-dimethylbenz[a]anthracene and 12-o-tetradecanoyl phorbol-13-acetate induced skin carcinogenesis through alleviation of oxidative stress.
    Asian Pacific journal of cancer prevention : APJCP, 2013, Volume: 14, Issue:5

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Antioxidants; Cell Proliferation; Cell Transformation, Neoplastic; Diet; Female; Fermentation; Lipid Peroxidation; Mice; Mice, Inbred BALB C; Oxidative Stress; Plant Preparations; Probiotics; Prunus; Skin; Skin Neoplasms; Superoxide Dismutase; Tetradecanoylphorbol Acetate

2013
The effects of dissociated glucocorticoids RU24858 and RU24782 on TPA-induced skin tumor promotion biomarkers in SENCAR mice.
    Molecular carcinogenesis, 2014, Volume: 53, Issue:6

    Topics: Animals; Animals, Outbred Strains; Anticarcinogenic Agents; Biomarkers; Cell Proliferation; Cell Transformation, Neoplastic; Cyclooxygenase 2; Desoximetasone; Epidermis; Female; Gene Expression Regulation; Glucocorticoids; Hyperplasia; Interleukin-6; Mice; Nitric Oxide Synthase Type II; Proto-Oncogene Proteins c-jun; RNA, Messenger; Skin Neoplasms; Tetradecanoylphorbol Acetate

2014
S100A14: novel modulator of terminal differentiation in esophageal cancer.
    Molecular cancer research : MCR, 2013, Volume: 11, Issue:12

    Topics: Calcium; Calcium-Binding Proteins; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Filaggrin Proteins; G1 Phase Cell Cycle Checkpoints; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Intermediate Filament Proteins; Neoplasm Grading; Neoplasm Staging; Protein Precursors; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription Factors

2013
Impact of mTORC1 inhibition on keratinocyte proliferation during skin tumor promotion in wild-type and BK5.AktWT mice.
    Molecular carcinogenesis, 2014, Volume: 53, Issue:11

    Topics: Animals; Antibiotics, Antineoplastic; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Chromones; ErbB Receptors; Female; Flavonoids; Hair Follicle; Hyperplasia; Keratinocytes; Male; Mechanistic Target of Rapamycin Complex 1; Mice; Mice, Inbred ICR; Mice, Transgenic; Morpholines; Multiprotein Complexes; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Proto-Oncogene Proteins c-akt; Signal Transduction; Sirolimus; Skin Neoplasms; Tetradecanoylphorbol Acetate; TOR Serine-Threonine Kinases

2014
Genome-wide screening of aberrant DNA methylation which associated with gene expression in mouse skin cancers.
    Molecular carcinogenesis, 2015, Volume: 54, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Azacitidine; Cell Line, Tumor; Cell Transformation, Neoplastic; DNA Methylation; Enzyme Inhibitors; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Mice, Inbred C57BL; Papilloma; Promoter Regions, Genetic; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factor AP-2

2015
A derivative of chrysin suppresses two-stage skin carcinogenesis by inhibiting mitogen- and stress-activated kinase 1.
    Cancer prevention research (Philadelphia, Pa.), 2014, Volume: 7, Issue:1

    Topics: Animals; Anticarcinogenic Agents; Cell Cycle; Cell Proliferation; Cell Transformation, Neoplastic; Flavones; Flavonoids; Histones; Male; Mice; p38 Mitogen-Activated Protein Kinases; Papilloma; Phenethylamines; Phosphorylation; Protein Structure, Tertiary; Ribosomal Protein S6 Kinases, 90-kDa; Signal Transduction; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate

2014
Silibinin inhibits tumor promotional triggers and tumorigenesis against chemically induced two-stage skin carcinogenesis in Swiss albino mice: possible role of oxidative stress and inflammation.
    Nutrition and cancer, 2014, Volume: 66, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Carcinogenesis; Catalase; Cell Transformation, Neoplastic; Chemoprevention; Cyclooxygenase 2; Down-Regulation; Female; Glucosephosphate Dehydrogenase; Inflammation; Interleukin-1beta; Interleukin-6; Lipid Peroxidation; Mice; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidative Stress; Silybin; Silymarin; Skin; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Up-Regulation; Vascular Endothelial Growth Factor A

2014
Selective proliferation of normal human melanocytes in vitro in the presence of phorbol ester and cholera toxin by Eisinger and Marko.
    Experimental dermatology, 2014, Volume: 23, Issue:1

    Topics: Cell Culture Techniques; Cell Proliferation; Cell Transformation, Neoplastic; Cholera Toxin; Culture Media; Dermatology; History, 20th Century; Humans; Melanocytes; Tetradecanoylphorbol Acetate

2014
S100A9 has a protective role in inflammation-induced skin carcinogenesis.
    International journal of cancer, 2014, Aug-15, Volume: 135, Issue:4

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Calgranulin A; Calgranulin B; Carcinogenesis; Cell Transformation, Neoplastic; Dimerization; Female; Gene Deletion; Gene Expression Regulation, Neoplastic; Inflammation; Keratinocytes; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neutrophils; Skin Neoplasms; T-Lymphocytes; Tetradecanoylphorbol Acetate

2014
Requirement and epigenetics reprogramming of Nrf2 in suppression of tumor promoter TPA-induced mouse skin cell transformation by sulforaphane.
    Cancer prevention research (Philadelphia, Pa.), 2014, Volume: 7, Issue:3

    Topics: Animals; Anticarcinogenic Agents; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Isothiocyanates; Mice; NF-E2-Related Factor 2; Skin Neoplasms; Sulfoxides; Tetradecanoylphorbol Acetate

2014
A novel mechanism of skin tumor promotion involving interferon-gamma (IFNγ)/signal transducer and activator of transcription-1 (Stat1) signaling.
    Molecular carcinogenesis, 2015, Volume: 54, Issue:8

    Topics: Animals; Anthracenes; Cell Transformation, Neoplastic; Cells, Cultured; Female; Humans; Interferon Regulatory Factor-1; Interferon-gamma; Keratinocytes; Mice; Neoplasms, Experimental; Phosphorylation; Signal Transduction; Skin Neoplasms; STAT1 Transcription Factor; Tetradecanoylphorbol Acetate

2015
Targeted deletion of RasGRP1 impairs skin tumorigenesis.
    Carcinogenesis, 2014, Volume: 35, Issue:5

    Topics: Animals; Cell Transformation, Neoplastic; Codon; Gene Deletion; Gene Targeting; Genes, ras; Guanine Nucleotide Exchange Factors; Hyperplasia; Mice; Mice, Knockout; Mutation; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcriptional Activation

2014
Tumor promoter-induced sulfiredoxin is required for mouse skin tumorigenesis.
    Carcinogenesis, 2014, Volume: 35, Issue:5

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Cell Line; Cell Proliferation; Cell Transformation, Neoplastic; Disease Models, Animal; Gene Expression Regulation; JNK Mitogen-Activated Protein Kinases; Mice; Mice, Knockout; Mitogen-Activated Protein Kinases; Oxidation-Reduction; Oxidoreductases Acting on Sulfur Group Donors; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcriptional Activation

2014
Epidermal barrier defects link atopic dermatitis with altered skin cancer susceptibility.
    eLife, 2014, May-05, Volume: 3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cell Communication; Cell Differentiation; Cell Transformation, Neoplastic; Cytokines; Dermatitis, Atopic; Disease Models, Animal; Epidermis; Keratinocytes; Membrane Proteins; Mice, 129 Strain; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Mice, Nude; NK Cell Lectin-Like Receptor Subfamily K; Papilloma; Permeability; Plakins; Protein Precursors; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Thymic Stromal Lymphopoietin; Time Factors

2014
Meis1 regulates epidermal stem cells and is required for skin tumorigenesis.
    PloS one, 2014, Volume: 9, Issue:7

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adult Stem Cells; Animals; Carcinogens; Carcinoma; Cell Differentiation; Cell Proliferation; Cell Transformation, Neoplastic; Disease Progression; Gene Expression Regulation, Neoplastic; Hair Follicle; Homeodomain Proteins; Keratinocytes; Mice; Mice, Transgenic; Multipotent Stem Cells; Myeloid Ecotropic Viral Integration Site 1 Protein; Neoplasm Proteins; Papilloma; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate

2014
Carcinogenic potential of metal nanoparticles in BALB/3T3 cell transformation assay.
    Environmental toxicology, 2016, Volume: 31, Issue:5

    Topics: 3T3 Cells; Animals; Carcinogens; Cell Survival; Cell Transformation, Neoplastic; Cerium; Ferrosoferric Oxide; Gold; Metal Nanoparticles; Methylcholanthrene; Mice; Mice, Inbred BALB C; Microscopy, Electron; Tetradecanoylphorbol Acetate

2016
Comparison of the inhibitory effects of delphinidin and its glycosides on cell transformation.
    Planta medica, 2015, Volume: 81, Issue:1

    Topics: Animals; Anthocyanins; Cell Line; Cell Transformation, Neoplastic; Drug Evaluation, Preclinical; Glucosides; MAP Kinase Kinase 1; Mice; Models, Molecular; Molecular Structure; Phosphorylation; Quartz Crystal Microbalance Techniques; Tetradecanoylphorbol Acetate

2015
Immature myeloid cells directly contribute to skin tumor development by recruiting IL-17-producing CD4+ T cells.
    The Journal of experimental medicine, 2015, Mar-09, Volume: 212, Issue:3

    Topics: Animals; Calgranulin B; CD4-Positive T-Lymphocytes; Cell Transformation, Neoplastic; Chemokine CCL4; Colitis; Female; Humans; Mice, Transgenic; Myeloid Cells; Skin Neoplasms; Tetradecanoylphorbol Acetate

2015
Conditional disruption of rictor demonstrates a direct requirement for mTORC2 in skin tumor development and continued growth of established tumors.
    Carcinogenesis, 2015, Volume: 36, Issue:4

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogens; Carrier Proteins; Caspase 3; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; Chemoprevention; Keratinocytes; Mechanistic Target of Rapamycin Complex 2; Mice; Mice, Inbred C57BL; Mice, Transgenic; Multiprotein Complexes; Proto-Oncogene Proteins c-akt; Rapamycin-Insensitive Companion of mTOR Protein; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; TOR Serine-Threonine Kinases; Ultraviolet Rays

2015
Keratinocyte p38δ loss inhibits Ras-induced tumor formation, while systemic p38δ loss enhances skin inflammation in the early phase of chemical carcinogenesis in mouse skin.
    Molecular carcinogenesis, 2016, Volume: 55, Issue:5

    Topics: Animals; Benz(a)Anthracenes; Cell Transformation, Neoplastic; Inflammation; Mice; Mice, Nude; Mitogen-Activated Protein Kinase 13; ras Proteins; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate

2016
Dehydroglyasperin C suppresses TPA-induced cell transformation through direct inhibition of MKK4 and PI3K.
    Molecular carcinogenesis, 2016, Volume: 55, Issue:5

    Topics: Animals; Benzopyrans; Carcinogens; Cell Line; Cell Line, Tumor; Cell Survival; Cell Transformation, Neoplastic; Cyclooxygenase 2; Gene Expression Regulation, Neoplastic; Humans; MAP Kinase Kinase 4; Mice; NF-kappa B; Phosphatidylinositol 3-Kinases; Protein Binding; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factor AP-1

2016
Notch1 Activation or Loss Promotes HPV-Induced Oral Tumorigenesis.
    Cancer research, 2015, Sep-15, Volume: 75, Issue:18

    Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Carcinogens; Carcinoma, Verrucous; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cocarcinogenesis; Disease Progression; DNA Transposable Elements; Female; Humans; Mice; Mice, Transgenic; Mouth Neoplasms; Mutagenesis, Insertional; Neoplasm Invasiveness; Oncogenes; Papilloma; Papillomaviridae; Receptor, Notch1; Skin Neoplasms; Specific Pathogen-Free Organisms; Tamoxifen; Tetradecanoylphorbol Acetate; Tumor Virus Infections; Uterine Cervical Neoplasms

2015
Low dose triterpene-quinone fraction from Ardisia crispa root precludes chemical-induced mouse skin tumor promotion.
    BMC complementary and alternative medicine, 2015, Dec-05, Volume: 15, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Anticarcinogenic Agents; Ardisia; Cell Transformation, Neoplastic; Chemical Fractionation; Chemoprevention; Curcumin; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Male; Mice; Mice, Inbred ICR; Plant Extracts; Plant Roots; Quinones; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Triterpenes

2015
Fractionation of a tumor-initiating UV dose introduces DNA damage-retaining cells in hairless mouse skin and renders subsequent TPA-promoted tumors non-regressing.
    Oncotarget, 2016, Feb-16, Volume: 7, Issue:7

    Topics: Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; DNA Damage; Epidermis; Female; Hyperplasia; Immunoenzyme Techniques; Male; Mice; Mice, Hairless; Mutation; Real-Time Polymerase Chain Reaction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53; Ultraviolet Rays

2016
Epigenetic blockade of neoplastic transformation by bromodomain and extra-terminal (BET) domain protein inhibitor JQ-1.
    Biochemical pharmacology, 2016, 10-01, Volume: 117

    Topics: Acetylation; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Azepines; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Cyclooxygenase 2; E1A-Associated p300 Protein; Epidermis; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Genes, Reporter; Histones; Humans; Mice; Nuclear Proteins; Promoter Regions, Genetic; Protein Processing, Post-Translational; RNA Interference; Tetradecanoylphorbol Acetate; Transcription Factors; Triazoles

2016
Lgr4 is crucial for skin carcinogenesis by regulating MEK/ERK and Wnt/β-catenin signaling pathways.
    Cancer letters, 2016, 12-28, Volume: 383, Issue:2

    Topics: Animals; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Cyclin D1; Extracellular Signal-Regulated MAP Kinases; Genetic Predisposition to Disease; Humans; Keratinocytes; MAP Kinase Kinase 1; Mice, Knockout; Neoplasms, Experimental; Papilloma; Phenotype; Receptors, G-Protein-Coupled; RNA Interference; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Transcription Factor AP-1; Transfection; Wnt Signaling Pathway

2016
Elevated ΔNp63α Levels Facilitate Epidermal and Biliary Oncogenic Transformation.
    The Journal of investigative dermatology, 2017, Volume: 137, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bile Duct Neoplasms; Cell Transformation, Neoplastic; Cells, Cultured; Cellular Senescence; Hyperplasia; Mice; Mice, Inbred C57BL; Mice, Transgenic; Phosphoproteins; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Trans-Activators

2017
Suppression of skin tumorigenesis in CD109-deficient mice.
    Oncotarget, 2016, Dec-13, Volume: 7, Issue:50

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, CD; Apoptosis; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; DNA Damage; Genes, ras; Genetic Predisposition to Disease; Keratinocytes; Mice, Knockout; Mutation; Neoplasm Proteins; NF-E2-Related Factor 2; Papilloma; Phenotype; Phosphorylation; Signal Transduction; Skin Neoplasms; Smad2 Protein; Tetradecanoylphorbol Acetate; Time Factors; Transforming Growth Factor beta1

2016
Involvement of the antioxidative property of morusin in blocking phorbol ester-induced malignant transformation of JB6 P
    Chemico-biological interactions, 2017, Feb-25, Volume: 264

    Topics: Animals; Anticarcinogenic Agents; Antioxidants; Carcinogens; Cell Line; Cell Movement; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Cyclooxygenase 2; Epidermal Cells; Epidermis; Flavonoids; Mice; Mice, Inbred BALB C; NF-kappa B; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Transcription Factor AP-1

2017
The resveratrol analogue 3,5,3',4',5'-pentahydroxy-trans-stilbene inhibits cell transformation via MEK.
    International journal of cancer, 2008, Dec-01, Volume: 123, Issue:11

    Topics: Adenosine Triphosphate; Animals; Cell Line; Cell Transformation, Neoplastic; Extracellular Signal-Regulated MAP Kinases; Mice; Mitogen-Activated Protein Kinase Kinases; Models, Molecular; Molecular Structure; Phosphorylation; Promoter Regions, Genetic; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-raf; Resveratrol; Ribosomal Protein S6 Kinases, 90-kDa; Stilbenes; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcriptional Activation

2008
Ligand activation of peroxisome proliferator-activated receptor beta/delta (PPAR beta/delta) inhibits chemically induced skin tumorigenesis.
    Carcinogenesis, 2008, Volume: 29, Issue:12

    Topics: Acetone; Animals; Carcinogens; Cell Differentiation; Cell Proliferation; Cell Transformation, Neoplastic; Enzyme Activation; Female; Keratinocytes; Ligands; Mice; Mice, Mutant Strains; PPAR delta; PPAR-beta; Skin Neoplasms; Tetradecanoylphorbol Acetate; Thiazoles

2008
Promotion of mouse two-stage skin carcinogenesis by diacylglycerol-rich edible oil.
    Cancer letters, 2009, Mar-08, Volume: 275, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Diglycerides; Fatty Acids; Female; Fluocinolone Acetonide; Linoleic Acid; Mice; Oils; Oleic Acid; Protein Kinase C; Skin Neoplasms; Tetradecanoylphorbol Acetate

2009
A novel Src kinase inhibitor reduces tumour formation in a skin carcinogenesis model.
    Carcinogenesis, 2009, Volume: 30, Issue:2

    Topics: Adult; Aged; Animals; Anticarcinogenic Agents; Benzodioxoles; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Disease Models, Animal; Female; Humans; Keratinocytes; Keratosis; Male; Mice; Middle Aged; Papilloma; Precancerous Conditions; Quinazolines; Skin Neoplasms; src-Family Kinases; Tetradecanoylphorbol Acetate

2009
Inducible cutaneous inflammation reveals a protumorigenic role for keratinocyte CXCR2 in skin carcinogenesis.
    Cancer research, 2009, Jan-01, Volume: 69, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Drug Eruptions; Enzyme Activation; Female; Hair Follicle; HeLa Cells; Humans; Keratinocytes; Ligands; Male; Mice; Neutrophils; Protein Kinase C-alpha; Receptors, Interleukin-8B; Skin Neoplasms; Tetradecanoylphorbol Acetate

2009
Transient receptor potential type vanilloid 1 suppresses skin carcinogenesis.
    Cancer research, 2009, Feb-01, Volume: 69, Issue:3

    Topics: Animals; Carcinogens; Cell Line, Tumor; Cell Transformation, Neoplastic; Down-Regulation; ErbB Receptors; Lysosomes; Mice; Mice, Knockout; Protein Structure, Tertiary; Proto-Oncogene Proteins c-cbl; Skin Neoplasms; Tetradecanoylphorbol Acetate; TRPV Cation Channels; Ubiquitin

2009
The coactivator CRTC1 promotes cell proliferation and transformation via AP-1.
    Proceedings of the National Academy of Sciences of the United States of America, 2009, Feb-03, Volume: 106, Issue:5

    Topics: Cell Proliferation; Cell Transformation, Neoplastic; DNA-Binding Proteins; HeLa Cells; Humans; Immunoprecipitation; Nuclear Proteins; Promoter Regions, Genetic; Proto-Oncogene Mas; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Tetradecanoylphorbol Acetate; Trans-Activators; Transcription Factor AP-1; Transcription Factors; Transcriptional Activation

2009
Selective role for Mek1 but not Mek2 in the induction of epidermal neoplasia.
    Cancer research, 2009, May-01, Volume: 69, Issue:9

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Differentiation; Cell Transformation, Neoplastic; Genotype; Hyperplasia; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Mice; Mice, Knockout; Mice, Transgenic; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Oncogene Protein v-akt; Papilloma; Phosphorylation; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate

2009
Linoleic acid metabolite suppresses skin inflammation and tumor promotion in mice: possible roles of programmed cell death 4 induction.
    Carcinogenesis, 2009, Volume: 30, Issue:7

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Apoptosis Regulatory Proteins; Cell Transformation, Neoplastic; Dermatitis; Extracellular Signal-Regulated MAP Kinases; Fatty Acids, Unsaturated; Female; Linoleic Acid; Lipopolysaccharides; Mice; Mice, Inbred ICR; RNA-Binding Proteins; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Tumor Suppressor Proteins

2009
Identification of the B-Raf/Mek/Erk MAP kinase pathway as a target for all-trans retinoic acid during skin cancer promotion.
    Molecular cancer, 2009, May-11, Volume: 8

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Blotting, Western; Carcinogens; Cell Transformation, Neoplastic; Extracellular Signal-Regulated MAP Kinases; Female; Gene Expression; Immunohistochemistry; MAP Kinase Kinase Kinases; Mice; Oligonucleotide Array Sequence Analysis; Proto-Oncogene Proteins B-raf; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin

2009
A regulatory mechanism for RSK2 NH(2)-terminal kinase activity.
    Cancer research, 2009, May-15, Volume: 69, Issue:10

    Topics: Binding Sites; Cell Division; Cell Line, Tumor; Cell Transformation, Neoplastic; Epidermal Growth Factor; Humans; Kaempferols; Kinetics; Lysine; Neoplasms; Phosphorylation; Protein Kinases; Recombinant Proteins; Reference Values; Ribosomal Protein S6 Kinases, 90-kDa; Skin; Tetradecanoylphorbol Acetate; Tissue Array Analysis; Valine

2009
SirT1-null mice develop tumors at normal rates but are poorly protected by resveratrol.
    Oncogene, 2009, Aug-13, Volume: 28, Issue:32

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Angiogenesis Inhibitors; Animals; Blood Vessels; Carcinogens; Cell Transformation, Neoplastic; Female; Genotype; Immunohistochemistry; Intestinal Polyps; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Knockout; Neoplasms, Experimental; NIH 3T3 Cells; Resveratrol; Sirtuin 1; Sirtuins; Skin Neoplasms; Stilbenes; Tetradecanoylphorbol Acetate; Transfection

2009
Photodynamic therapy with 5-aminolevulinic acid and diamino acid derivatives of protoporphyrin IX reduces papillomas in mice without eliminating transformation into squamous cell carcinoma of the skin.
    International journal of cancer, 2009, Oct-01, Volume: 125, Issue:7

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Aminolevulinic Acid; Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Kaplan-Meier Estimate; Mice; Mice, Inbred Strains; Papilloma; Photochemotherapy; Photosensitizing Agents; Protoporphyrins; Skin Neoplasms; Tetradecanoylphorbol Acetate

2009
Cellular dichotomy between anchorage-independent growth responses to bFGF and TPA reflects molecular switch in commitment to carcinogenesis.
    Molecular carcinogenesis, 2009, Volume: 48, Issue:11

    Topics: Animals; Base Sequence; Basic-Leucine Zipper Transcription Factors; Cell Adhesion; Cell Division; Cell Line, Tumor; Cell Transformation, Neoplastic; DNA Primers; DNA-Binding Proteins; Fibroblast Growth Factor 2; Humans; Mice; Oligonucleotide Array Sequence Analysis; Tetradecanoylphorbol Acetate; Transcription Factors; Transcription, Genetic

2009
T-box-expressed-in-T-cells (T-bet) expression by the tumor cells of hairy-cell leukemia correlates with interferon-gamma production.
    Leukemia & lymphoma, 2009, Volume: 50, Issue:10

    Topics: Antigens, CD; Antigens, CD19; Antigens, Neoplasm; B-Lymphocyte Subsets; Cell Transformation, Neoplastic; Cells, Cultured; Cytokines; Enterotoxins; Gene Expression Regulation, Leukemic; Humans; Immunophenotyping; Integrin alpha Chains; Interferon-gamma; Ionomycin; Leukemia, Hairy Cell; Neoplasm Proteins; T-Box Domain Proteins; T-Lymphocytes; Tetradecanoylphorbol Acetate

2009
All-trans retinoic acid suppresses Stat3 signaling during skin carcinogenesis.
    Cancer prevention research (Philadelphia, Pa.), 2009, Volume: 2, Issue:10

    Topics: Animals; Antineoplastic Agents; Blotting, Western; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Extracellular Signal-Regulated MAP Kinases; Female; Immunohistochemistry; MAP Kinase Kinase Kinases; Mice; Mice, Inbred SENCAR; Mice, Transgenic; raf Kinases; Signal Transduction; Skin Neoplasms; STAT3 Transcription Factor; Tetradecanoylphorbol Acetate; Tretinoin

2009
Piceatannol inhibits phorbol ester-induced NF-kappa B activation and COX-2 expression in cultured human mammary epithelial cells.
    Nutrition and cancer, 2009, Volume: 61, Issue:6

    Topics: Anti-Inflammatory Agents; Antioxidants; Breast; Breast Neoplasms; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Cyclooxygenase 2; DNA-Binding Proteins; Dose-Response Relationship, Drug; Down-Regulation; Epithelial Cells; Female; Humans; I-kappa B Kinase; NF-kappa B; Phosphorylation; Protein Transport; Stilbenes; Tetradecanoylphorbol Acetate

2009
Transforming growth factor beta1 enhances tumor promotion in mouse skin carcinogenesis.
    Carcinogenesis, 2010, Volume: 31, Issue:6

    Topics: Animals; Carcinogens; Cell Proliferation; Cell Transformation, Neoplastic; Mice; Mice, Inbred BALB C; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta1

2010
Anti-tumor-initiating effects of spiro-biflavonoids from Abies sachalinensis.
    Chemistry & biodiversity, 2010, Volume: 7, Issue:9

    Topics: Abies; Animals; Anticarcinogenic Agents; Biflavonoids; Carcinogenicity Tests; Cell Transformation, Neoplastic; Cells, Cultured; Cocarcinogenesis; Female; Humans; Mice; Mice, Inbred ICR; Molecular Structure; Peroxynitrous Acid; Plant Bark; Skin Neoplasms; Spiro Compounds; Tetradecanoylphorbol Acetate

2010
Loss of tumor progression locus 2 (tpl2) enhances tumorigenesis and inflammation in two-stage skin carcinogenesis.
    Oncogene, 2011, Jan-27, Volume: 30, Issue:4

    Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Cytokines; Female; Immunoblotting; Immunohistochemistry; Inflammation; Male; MAP Kinase Kinase Kinases; Mice; Mice, Inbred C57BL; Mice, Transgenic; Proto-Oncogene Proteins; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate

2011
Dual function of MyD88 in RAS signaling and inflammation, leading to mouse and human cell transformation.
    The Journal of clinical investigation, 2010, Volume: 120, Issue:10

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Cycle; Cell Transformation, Neoplastic; Extracellular Signal-Regulated MAP Kinases; Humans; Inflammation; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Myeloid Differentiation Factor 88; Phosphorylation; ras Proteins; Signal Transduction; Tetradecanoylphorbol Acetate

2010
Intrinsic cooperation between p16INK4a and p21Waf1/Cip1 in the onset of cellular senescence and tumor suppression in vivo.
    Cancer research, 2010, Nov-15, Volume: 70, Issue:22

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Blotting, Western; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p15; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p21; Embryo, Mammalian; Fibroblasts; Histones; Mice; Mice, Inbred C57BL; Mice, Knockout; Octamer Transcription Factor-3; ras Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Skin Neoplasms; Tetradecanoylphorbol Acetate

2010
IL-17 enhances tumor development in carcinogen-induced skin cancer.
    Cancer research, 2010, Dec-15, Volume: 70, Issue:24

    Topics: Aniline Compounds; Animals; Carcinogens; CD11b Antigen; Cell Growth Processes; Cell Transformation, Neoplastic; Gene Expression Regulation, Neoplastic; Interferon-gamma; Interleukin-17; Mice; Mice, Inbred C57BL; Mice, Knockout; Skin; Skin Neoplasms; STAT3 Transcription Factor; Tetradecanoylphorbol Acetate; Tumor Microenvironment

2010
p-HPEA-EDA, a phenolic compound of virgin olive oil, activates AMP-activated protein kinase to inhibit carcinogenesis.
    Carcinogenesis, 2011, Volume: 32, Issue:4

    Topics: Aldehydes; AMP-Activated Protein Kinases; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Survival; Cell Transformation, Neoplastic; Cyclooxygenase 2; Cyclopentane Monoterpenes; Enzyme Activation; Humans; Olive Oil; Phenols; Plant Oils; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53

2011
FSP1+ fibroblasts promote skin carcinogenesis by maintaining MCP-1-mediated macrophage infiltration and chronic inflammation.
    The American journal of pathology, 2011, Volume: 178, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Proliferation; Cell Transformation, Neoplastic; Chemokine CCL2; Chronic Disease; Fibroblasts; Humans; Inflammation; Macrophages; Mice; Mice, Inbred BALB C; Mice, Transgenic; Skin Neoplasms; Tetradecanoylphorbol Acetate

2011
Evodiamine inhibits 12-O-tetradecanoylphorbol-13-acetate-induced activator protein 1 transactivation and cell transformation in human hepatocytes.
    Phytotherapy research : PTR, 2011, Volume: 25, Issue:7

    Topics: Antineoplastic Agents, Phytogenic; Cell Line; Cell Transformation, Neoplastic; Evodia; Extracellular Signal-Regulated MAP Kinases; Hepatocytes; Humans; Phosphorylation; Plant Extracts; Quinazolines; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcriptional Activation; Transfection

2011
Inhibitory effects of Zuo-Jin-Wan and its alkaloidal ingredients on activator protein 1, nuclear factor-κB, and cellular transformation in HepG2 cells.
    Fitoterapia, 2011, Volume: 82, Issue:4

    Topics: Antineoplastic Agents, Phytogenic; Berberine; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Coptis; Drugs, Chinese Herbal; Evodia; Hep G2 Cells; Humans; Liver Neoplasms; NF-kappa B; Plant Extracts; Quinazolines; Tetradecanoylphorbol Acetate; Transcription Factor AP-1

2011
5'-Nitro-indirubinoxime inhibits epidermal growth factor- and phorbol ester-induced AP-1 activity and cell transformation through inhibition of phosphorylation of Pin1.
    Molecular carcinogenesis, 2011, Volume: 50, Issue:12

    Topics: Animals; Anticarcinogenic Agents; Cell Line; Cell Transformation, Neoplastic; Epidermal Growth Factor; Indoles; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinases; NIMA-Interacting Peptidylprolyl Isomerase; Oximes; Peptidylprolyl Isomerase; Phosphorylation; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-raf; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription, Genetic; Transcriptional Activation

2011
Effects of psoralen from Psoralea corylifolia on quinone reductase, ornithine decarboxylase, and JB6 cells transformation promotion.
    Archives of pharmacal research, 2011, Volume: 34, Issue:1

    Topics: Animals; Anticarcinogenic Agents; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Enzyme Induction; Epidermal Cells; Epidermis; Ficusin; Inhibitory Concentration 50; Mice; NAD(P)H Dehydrogenase (Quinone); Ornithine Decarboxylase; Psoralea; Seeds; Tetradecanoylphorbol Acetate

2011
Conjugates of 3α-methoxyserrat-14-en-21β-ol (PJ-1) and 3β-methoxyserrat-14-en-21β-ol (PJ-2) as cancer chemopreventive agents.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:8

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antigens, Viral; Carcinogenicity Tests; Cell Transformation, Neoplastic; Epstein-Barr Virus Infections; Flavanones; Genistein; Herpesvirus 4, Human; Hesperidin; Isoflavones; Mice; Oleanolic Acid; Skin Neoplasms; Tetradecanoylphorbol Acetate; Triterpenes

2011
Loss of the miR-21 allele elevates the expression of its target genes and reduces tumorigenesis.
    Proceedings of the National Academy of Sciences of the United States of America, 2011, Jun-21, Volume: 108, Issue:25

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogens; Cell Proliferation; Cell Transformation, Neoplastic; Epidermal Cells; Epidermis; Female; Gene Expression Regulation, Neoplastic; Keratinocytes; Mice; Mice, Knockout; MicroRNAs; ras Proteins; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate

2011
Enhancing mitochondrial respiration suppresses tumor promoter TPA-induced PKM2 expression and cell transformation in skin epidermal JB6 cells.
    Cancer prevention research (Philadelphia, Pa.), 2011, Volume: 4, Issue:9

    Topics: Animals; Cell Respiration; Cell Transformation, Neoplastic; Humans; Malates; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mitochondria; Protein Isoforms; Pyruvate Kinase; Pyruvic Acid; RNA, Small Interfering; Skin; Skin Neoplasms; Succinic Acid; Superoxide Dismutase; Tetradecanoylphorbol Acetate

2011
CXCR3 enhances a T-cell-dependent epidermal proliferative response and promotes skin tumorigenesis.
    Cancer research, 2011, Sep-01, Volume: 71, Issue:17

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cell Proliferation; Cell Transformation, Neoplastic; Epidermis; Humans; Lymphocytes, Tumor-Infiltrating; Methylcholanthrene; Mice; Mice, Mutant Strains; Receptors, CXCR3; Skin Neoplasms; T-Lymphocytes; Tetradecanoylphorbol Acetate

2011
Claudin-18 is an early-stage marker of pancreatic carcinogenesis.
    The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 2011, Volume: 59, Issue:10

    Topics: Adenocarcinoma, Mucinous; Biomarkers, Tumor; Carcinoma, Pancreatic Ductal; Carcinoma, Papillary; Cell Transformation, Neoplastic; Claudins; Enzyme Inhibitors; Humans; Indoles; Maleimides; Membrane Proteins; Pancreas; Pancreatic Neoplasms; Pancreatitis, Chronic; Protein Kinase C; Retrospective Studies; Stomach Neoplasms; Tetradecanoylphorbol Acetate

2011
Resveratrol and black tea polyphenol combination synergistically suppress mouse skin tumors growth by inhibition of activated MAPKs and p53.
    PloS one, 2011, Volume: 6, Issue:8

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Biomarkers, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Chemoprevention; Drug Screening Assays, Antitumor; Drug Synergism; Enzyme Activation; Male; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinases; Phosphorylation; Polyphenols; Proliferating Cell Nuclear Antigen; Protein Stability; Remission Induction; Resveratrol; Skin Neoplasms; Stilbenes; Tea; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53

2011
14-3-3σ and p63 play opposing roles in epidermal tumorigenesis.
    Carcinogenesis, 2011, Volume: 32, Issue:12

    Topics: 14-3-3 Proteins; 9,10-Dimethyl-1,2-benzanthracene; Animals; Blotting, Western; Carcinogens; Cell Differentiation; Cell Proliferation; Cell Transformation, Neoplastic; Gene Silencing; Homeostasis; Keratinocytes; Mice; Mice, Mutant Strains; Phosphoproteins; Polymerase Chain Reaction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Trans-Activators

2011
Origin of ruffles: linkage to other protrusions, filopodia and lamellae.
    Cellular signalling, 2012, Volume: 24, Issue:1

    Topics: Animals; Cell Line; Cell Shape; Cell Surface Extensions; Cell Transformation, Neoplastic; Epithelial Cells; Rats; Respiratory Mucosa; Signal Transduction; Tetradecanoylphorbol Acetate

2012
Loss of Trop2 promotes carcinogenesis and features of epithelial to mesenchymal transition in squamous cell carcinoma.
    Molecular cancer research : MCR, 2011, Volume: 9, Issue:12

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Neoplasm; Carcinoma, Squamous Cell; Cell Adhesion Molecules; Cell Dedifferentiation; Cell Line, Tumor; Cell Transformation, Neoplastic; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Keratinocytes; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Skin Neoplasms; Tetradecanoylphorbol Acetate

2011
Loss of the platelet activating factor receptor in mice augments PMA-induced inflammation and cutaneous chemical carcinogenesis.
    Carcinogenesis, 2012, Volume: 33, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Inflammation; Mice; Mice, Inbred C57BL; Mice, Knockout; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled; Signal Transduction; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate

2012
Prostaglandin modulation of phorbol ester skin tumor promotion.
    Carcinogenesis, 1980, Volume: 1, Issue:3

    Topics: Animals; Arachidonic Acid; Carcinogens; Cell Transformation, Neoplastic; Cocarcinogenesis; Dinoprost; Dinoprostone; Female; Mice; Mice, Inbred SENCAR; Oxytocics; Papilloma; Prostaglandins; Skin Neoplasms; Tetradecanoylphorbol Acetate

1980
Cytotoxic activities and anti-tumor-promoting effects of microbial transformation products of prenylated chalcones from Angelica keiskei.
    Chemistry & biodiversity, 2012, Volume: 9, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Angelica; Animals; Antigens, Viral; Antineoplastic Agents, Phytogenic; Apoptosis; Aspergillus; Carcinogenicity Tests; Carcinogens; Cell Transformation, Neoplastic; Chalcones; Humans; Mice; Molecular Structure; Prenylation; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

2012
Cucurbitane triterpenoids from the leaves of Momordica charantia, and their cancer chemopreventive effects and cytotoxicities.
    Chemistry & biodiversity, 2012, Volume: 9, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Viral; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinogens; Cell Transformation, Neoplastic; Glycosides; Humans; Mice; Molecular Structure; Momordica charantia; Plant Leaves; Skin Neoplasms; Tetradecanoylphorbol Acetate; Triterpenes; Tumor Cells, Cultured

2012
MicroRNA-212 displays tumor-promoting properties in non-small cell lung cancer cells and targets the hedgehog pathway receptor PTCH1.
    Molecular biology of the cell, 2012, Volume: 23, Issue:8

    Topics: Antibodies, Monoclonal; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Gene Expression Regulation, Neoplastic; Hedgehog Proteins; Humans; Lung Neoplasms; MicroRNAs; Patched Receptors; Patched-1 Receptor; Receptors, Cell Surface; RNA Interference; RNA, Small Interfering; Signal Transduction; Tetradecanoylphorbol Acetate

2012
A keratin 15 containing stem cell population from the hair follicle contributes to squamous papilloma development in the mouse.
    Molecular carcinogenesis, 2013, Volume: 52, Issue:10

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Transformation, Neoplastic; Female; Genes, ras; Hair Follicle; Humans; Integrases; Keratin-15; Keratinocytes; Laser Capture Microdissection; Mice; Mice, Transgenic; Mutation; Papilloma; Skin; Skin Neoplasms; Stem Cells; Tetradecanoylphorbol Acetate

2013
Deficiency of the Kruppel-like factor KLF4 correlates with increased cell proliferation and enhanced skin tumorigenesis.
    Carcinogenesis, 2012, Volume: 33, Issue:6

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cell Adhesion; Cell Differentiation; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; Female; Gene Expression Regulation, Neoplastic; Humans; Keratinocytes; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Mice; Mice, Transgenic; RNA Interference; RNA, Small Interfering; Skin Neoplasms; Tamoxifen; Tetradecanoylphorbol Acetate

2012
MicroRNA-29a and microRNA-142-3p are regulators of myeloid differentiation and acute myeloid leukemia.
    Blood, 2012, May-24, Volume: 119, Issue:21

    Topics: Antineoplastic Agents; Carcinogens; Cell Differentiation; Cell Line, Tumor; Cell Transformation, Neoplastic; Gene Expression Regulation, Leukemic; HEK293 Cells; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; MicroRNAs; Myeloid Cells; Tetradecanoylphorbol Acetate; Transfection; Tretinoin

2012
Phosphoinositol 3-kinase, a novel target molecule for the inhibitory effects of juglone on TPA-induced cell transformation.
    International journal of molecular medicine, 2012, Volume: 30, Issue:1

    Topics: Androstadienes; Animals; Cell Line; Cell Transformation, Neoplastic; Chromones; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Endothelial Growth Factors; Extracellular Signal-Regulated MAP Kinases; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Mice; Morpholines; Naphthoquinones; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-fos; Ribosomal Protein S6 Kinases, 90-kDa; Skin; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Wortmannin

2012
Miz1 is a critical repressor of cdkn1a during skin tumorigenesis.
    PloS one, 2012, Volume: 7, Issue:4

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Differentiation; Cell Proliferation; Cell Transformation, Neoplastic; Cyclin-Dependent Kinase Inhibitor p15; Cyclin-Dependent Kinase Inhibitor p21; Mice; Mice, Transgenic; Neoplasms, Experimental; Nuclear Proteins; Protein Inhibitors of Activated STAT; Protein Structure, Tertiary; Skin Neoplasms; Tetradecanoylphorbol Acetate; Ubiquitin-Protein Ligases

2012
TPA-induced cell transformation provokes a complex formation between Pin1 and 90 kDa ribosomal protein S6 kinase 2.
    Molecular and cellular biochemistry, 2012, Volume: 367, Issue:1-2

    Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Enzyme Activation; Humans; Mice; NIMA-Interacting Peptidylprolyl Isomerase; Peptidylprolyl Isomerase; Phosphorylation; Protein Binding; Protein Interaction Mapping; Protein Processing, Post-Translational; Ribosomal Protein S6 Kinases, 90-kDa; Tetradecanoylphorbol Acetate

2012
Effects of the tropical ginger compound,1'-acetoxychavicol acetate, against tumor promotion in K5.Stat3C transgenic mice.
    Journal of experimental & clinical cancer research : CR, 2012, Jun-15, Volume: 31

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Alpinia; Animals; Benzyl Alcohols; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Fluocinolone Acetonide; Humans; Mice; Mice, Transgenic; NF-kappa B; Plant Extracts; Skin Neoplasms; STAT3 Transcription Factor; Tetradecanoylphorbol Acetate; Zingiber officinale

2012
A transposon-based analysis of gene mutations related to skin cancer development.
    The Journal of investigative dermatology, 2013, Volume: 133, Issue:1

    Topics: Animals; Carcinogens; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Carrier Proteins; Cell Transformation, Neoplastic; DNA Mutational Analysis; DNA Transposable Elements; Genes, ras; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Humans; Intracellular Signaling Peptides and Proteins; Keratin-15; Keratin-5; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Transgenic; Mutation; Nuclear Proteins; Promoter Regions, Genetic; Receptor, Notch1; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transposases

2013
Inhibition of CXCR2 profoundly suppresses inflammation-driven and spontaneous tumorigenesis.
    The Journal of clinical investigation, 2012, Volume: 122, Issue:9

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenoma; Animals; Animals, Inbred Strains; Azoxymethane; Cell Transformation, Neoplastic; Chemokines, CXC; Colitis; Colonic Neoplasms; Dermatitis, Contact; Dextran Sulfate; Gene Expression; Mice; Mice, 129 Strain; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Neutrophils; Papilloma; Peroxidase; Precancerous Conditions; Receptors, Interleukin-8B; Skin Neoplasms; Statistics, Nonparametric; Tetradecanoylphorbol Acetate; Tumor Burden

2012
Tissue-specific opposing functions of the inflammasome adaptor ASC in the regulation of epithelial skin carcinogenesis.
    Proceedings of the National Academy of Sciences of the United States of America, 2012, Nov-06, Volume: 109, Issue:45

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adaptor Proteins, Signal Transducing; Animals; Apoptosis Regulatory Proteins; CARD Signaling Adaptor Proteins; Caspase 1; Cell Proliferation; Cell Transformation, Neoplastic; Cytokines; Cytoskeletal Proteins; Down-Regulation; Epithelium; Humans; Inflammasomes; Inflammation; Keratinocytes; Mice; Mice, Knockout; Myeloid Cells; Neoplasms, Squamous Cell; Organ Specificity; Receptors, Interleukin-1; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Microenvironment; Tumor Suppressor Protein p53

2012
The p53-p66Shc apoptotic pathway is dispensable for tumor suppression whereas the p66Shc-generated oxidative stress initiates tumorigenesis.
    Current pharmaceutical design, 2013, Volume: 19, Issue:15

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogens; Cell Transformation, Neoplastic; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxidative Stress; Shc Signaling Adaptor Proteins; Src Homology 2 Domain-Containing, Transforming Protein 1; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53; Ultraviolet Rays

2013
Withaferin A suppresses tumor promoter 12-O-tetradecanoylphorbol 13-acetate-induced decreases in isocitrate dehydrogenase 1 activity and mitochondrial function in skin epidermal JB6 cells.
    Cancer science, 2013, Volume: 104, Issue:2

    Topics: Animals; Cell Line, Tumor; Cell Proliferation; Cell Respiration; Cell Transformation, Neoplastic; Down-Regulation; Epidermis; Female; Glycolysis; Isocitrate Dehydrogenase; Ketoglutaric Acids; Lactic Acid; Membrane Potential, Mitochondrial; Mice; Mice, Inbred DBA; Mitochondria; Tetradecanoylphorbol Acetate; Withanolides

2013
Baicalein inhibits DMBA/TPA-induced skin tumorigenesis in mice by modulating proliferation, apoptosis, and inflammation.
    Inflammation, 2013, Volume: 36, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Apoptosis; Cell Proliferation; Cell Transformation, Neoplastic; Female; Flavanones; Hyperplasia; Inflammation; Mice; Mice, Inbred C57BL; Plant Extracts; Scutellaria baicalensis; Skin Neoplasms; Tetradecanoylphorbol Acetate

2013
Inhibitory effects of Opuntia humifusa on 7, 12-dimethyl- benz[a]anthracene and 12-O-tetradecanoylphorbol-13- acetate induced two-stage skin carcinogenesis.
    Asian Pacific journal of cancer prevention : APJCP, 2012, Volume: 13, Issue:9

    Topics: Analysis of Variance; Animals; Anticarcinogenic Agents; Apoptosis; Benz(a)Anthracenes; Cell Transformation, Neoplastic; Female; Glutathione Transferase; Lipid Peroxidation; Mice; Mice, Inbred BALB C; Opuntia; Oxidative Stress; Phytotherapy; Plant Preparations; Skin; Skin Neoplasms; Statistics, Nonparametric; Superoxide Dismutase; Tetradecanoylphorbol Acetate

2012
High expression of microRNA‑127 is involved in cell cycle arrest in MC‑3 mucoepidermoid carcinoma cells.
    Molecular medicine reports, 2013, Volume: 7, Issue:2

    Topics: Animals; Carcinoma, Mucoepidermoid; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Fibroblasts; G1 Phase Cell Cycle Checkpoints; Humans; Mice; MicroRNAs; S Phase Cell Cycle Checkpoints; Salivary Gland Neoplasms; Sp1 Transcription Factor; Tetradecanoylphorbol Acetate; Transfection

2013
PKM2 inhibitor shikonin suppresses TPA-induced mitochondrial malfunction and proliferation of skin epidermal JB6 cells.
    Molecular carcinogenesis, 2014, Volume: 53, Issue:5

    Topics: AMP-Activated Protein Kinases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Blotting, Western; Carrier Proteins; Cell Adhesion; Cell Proliferation; Cell Respiration; Cell Transformation, Neoplastic; Cells, Cultured; Epidermis; Humans; Membrane Potential, Mitochondrial; Membrane Proteins; Mice; Mitochondria; Naphthoquinones; Oxygen Consumption; Tetradecanoylphorbol Acetate; Thyroid Hormone-Binding Proteins; Thyroid Hormones

2014
Peracetylated (-)-epigallocatechin-3-gallate (AcEGCG) potently prevents skin carcinogenesis by suppressing the PKD1-dependent signaling pathway in CD34+ skin stem cells and skin tumors.
    Carcinogenesis, 2013, Volume: 34, Issue:6

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetates; Animals; Antigens, CD34; Catechin; CCAAT-Enhancer-Binding Proteins; Cell Proliferation; Cell Transformation, Neoplastic; Chemoprevention; Cyclic AMP Response Element-Binding Protein; Cyclooxygenase 2; Extracellular Signal-Regulated MAP Kinases; Male; Mice; Mice, Inbred ICR; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinase 9; Mitotic Index; Nitric Oxide Synthase Type II; Ornithine Decarboxylase; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinase; Phosphorylation; Protein Kinase C; Proto-Oncogene Proteins c-akt; Skin Neoplasms; Stem Cells; Tetradecanoylphorbol Acetate; Vascular Endothelial Growth Factor A

2013
Aberrantly expressed c-Jun and JunB are a hallmark of Hodgkin lymphoma cells, stimulate proliferation and synergize with NF-kappa B.
    The EMBO journal, 2002, Aug-01, Volume: 21, Issue:15

    Topics: Cell Division; Cell Transformation, Neoplastic; Cyclin D2; Cyclins; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; Genes, jun; Hodgkin Disease; Humans; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; MAP Kinase Signaling System; Mitogens; Neoplasm Proteins; NF-kappa B; Proto-Oncogene Mas; Proto-Oncogene Proteins c-jun; Proto-Oncogene Proteins c-met; Receptors, CCR7; Receptors, Chemokine; Recombinant Fusion Proteins; Reed-Sternberg Cells; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription, Genetic; Transfection; Tumor Cells, Cultured; Ultraviolet Rays

2002
Cdk4 deficiency inhibits skin tumor development but does not affect normal keratinocyte proliferation.
    The American journal of pathology, 2002, Volume: 161, Issue:2

    Topics: Animals; Carcinogens; Cell Division; Cell Transformation, Neoplastic; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinases; Keratinocytes; Mice; Mice, Inbred C57BL; Mice, Knockout; Proto-Oncogene Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate

2002
PKC, p42/44 MAPK and p38 MAPK regulate hepatocyte growth factor secretion from human astrocytoma cells.
    Brain research. Molecular brain research, 2002, Jun-15, Volume: 102, Issue:1-2

    Topics: Astrocytoma; Cell Division; Cell Transformation, Neoplastic; Enzyme Inhibitors; Hepatocyte Growth Factor; Humans; MAP Kinase Kinase 1; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Neoplasm Invasiveness; p38 Mitogen-Activated Protein Kinases; Protein Kinase C; Protein Serine-Threonine Kinases; Protein Synthesis Inhibitors; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

2002
Flavanones structure-related inhibition on TPA-induced tumor promotion through suppression of extracellular signal-regulated protein kinases: involvement of prostaglandin E2 in anti-promotive process.
    Journal of cellular physiology, 2002, Volume: 193, Issue:1

    Topics: 3T3 Cells; Animals; Biphenyl Compounds; Carcinogens; Cell Division; Cell Transformation, Neoplastic; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Fibroblasts; Flavonoids; Free Radical Scavengers; Gene Expression Regulation; Isoenzymes; JNK Mitogen-Activated Protein Kinases; Mice; Mitogen-Activated Protein Kinases; Ornithine Decarboxylase; Phosphorylation; Picrates; Prostaglandin-Endoperoxide Synthases; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Thymidine

2002
Cell transformation by v-Jun deactivates ERK MAP kinase signalling.
    Oncogene, 2002, Sep-19, Volume: 21, Issue:42

    Topics: Animals; Blotting, Western; Cell Division; Cell Transformation, Neoplastic; Chick Embryo; Down-Regulation; Fibroblasts; Humans; Immunoenzyme Techniques; MAP Kinase Kinase Kinase 1; Mitogen-Activated Protein Kinases; Oncogene Protein p65(gag-jun); Phosphorylation; Protein Serine-Threonine Kinases; Retroviridae; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

2002
Identification of Dss1 as a 12-O-tetradecanoylphorbol-13-acetate-responsive gene expressed in keratinocyte progenitor cells, with possible involvement in early skin tumorigenesis.
    The Journal of biological chemistry, 2003, Jan-17, Volume: 278, Issue:3

    Topics: Animals; Base Sequence; Cell Cycle Proteins; Cell Division; Cell Transformation, Neoplastic; DNA Primers; Gene Expression Profiling; Gene Expression Regulation; In Situ Hybridization; Keratinocytes; Male; Mice; Proteins; Reverse Transcriptase Polymerase Chain Reaction; Skin Neoplasms; Subcellular Fractions; Tetradecanoylphorbol Acetate

2003
NS-398 and piroxicam suppress UVB-induced activator protein 1 activity by mechanisms independent of cyclooxygenase-2.
    The Journal of biological chemistry, 2003, Jan-24, Volume: 278, Issue:4

    Topics: Animals; Blotting, Western; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; DNA; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Isoenzymes; JNK Mitogen-Activated Protein Kinases; Luciferases; MAP Kinase Kinase 4; Membrane Proteins; Mice; Mitogen-Activated Protein Kinase Kinases; Nitrobenzenes; Phosphorylation; Piroxicam; Prostaglandin-Endoperoxide Synthases; Sulfonamides; Tetradecanoylphorbol Acetate; Time Factors; Transcription Factor AP-1; Transcription Factors; Ultraviolet Rays

2003
Matrix metalloproteinase-19 is expressed by proliferating epithelium but disappears with neoplastic dedifferentiation.
    International journal of cancer, 2003, Mar-01, Volume: 103, Issue:6

    Topics: Blotting, Northern; Blotting, Western; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cell Differentiation; Cell Division; Cell Transformation, Neoplastic; Down-Regulation; Female; Fibroblasts; Humans; Immunoenzyme Techniques; Keratinocytes; Male; Matrix Metalloproteinases, Secreted; Metalloendopeptidases; Middle Aged; RNA, Messenger; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

2003
Rhein inhibits TPA-induced activator protein-1 activation and cell transformation by blocking the JNK-dependent pathway.
    International journal of oncology, 2003, Volume: 22, Issue:4

    Topics: Animals; Anthraquinones; Blotting, Western; Cell Line; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Enzyme Inhibitors; JNK Mitogen-Activated Protein Kinases; Luciferases; MAP Kinase Kinase 4; Mice; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Models, Chemical; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Tetradecanoylphorbol Acetate; Time Factors; Transcription Factor AP-1; Transcription, Genetic; Transcriptional Activation

2003
Partial oncogenic transformation of chicken embryo fibroblasts by Jun dimerization protein 2, a negative regulator of TRE- and CRE-dependent transcription.
    Oncogene, 2003, Apr-10, Volume: 22, Issue:14

    Topics: Activating Transcription Factor 2; Animals; Cell Transformation, Neoplastic; Chick Embryo; Cyclic AMP Response Element-Binding Protein; Fibroblasts; Gene Expression Regulation, Neoplastic; Repressor Proteins; Response Elements; Tetradecanoylphorbol Acetate; Transcription Factors; Transfection

2003
IL-1 alpha, innate immunity, and skin carcinogenesis: the effect of constitutive expression of IL-1 alpha in epidermis on chemical carcinogenesis.
    Journal of immunology (Baltimore, Md. : 1950), 2003, Jun-01, Volume: 170, Issue:11

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; DNA-Binding Proteins; Epidermis; Female; Humans; Immunity, Innate; Interleukin-1; Keratin-14; Keratins; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Nuclear Proteins; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transgenes

2003
Enhancement of carcinogen-induced malignant cell transformation by prostaglandin F(2 alpha).
    Toxicology, 2003, Jun-30, Volume: 188, Issue:2-3

    Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Drug Synergism; Fibroblasts; Methylcholanthrene; Methylnitronitrosoguanidine; Mice; Mice, Inbred C3H; Nitrobenzenes; Polychlorinated Dibenzodioxins; Sulfonamides; Tetradecanoylphorbol Acetate

2003
Osteopontin induction is required for tumor promoter-induced transformation of preneoplastic mouse cells.
    Carcinogenesis, 2003, Volume: 24, Issue:11

    Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Dexamethasone; Fibronectins; Mice; Osteopontin; Precancerous Conditions; Serum Albumin, Bovine; Sialoglycoproteins; Tetradecanoylphorbol Acetate

2003
Anthocyanidins inhibit activator protein 1 activity and cell transformation: structure-activity relationship and molecular mechanisms.
    Carcinogenesis, 2004, Volume: 25, Issue:1

    Topics: Animals; Anthocyanins; Anthracenes; Anticarcinogenic Agents; Butadienes; Cell Transformation, Neoplastic; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinases; Nitriles; Phosphorylation; Structure-Activity Relationship; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Transcription Factor AP-1

2004
Novel mechanisms of sublethal oxidant toxicity: induction of premature senescence in human fibroblasts confers tumor promoter activity.
    Experimental cell research, 2003, Oct-15, Volume: 290, Issue:1

    Topics: Carcinogens; Cell Adhesion; Cell Communication; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cellular Senescence; Coculture Techniques; Connexin 43; Culture Media, Conditioned; Extracellular Matrix; Fibroblasts; Gap Junctions; Humans; Keratinocytes; Models, Biological; Neoplasms; Oxidants; Oxidative Stress; Tetradecanoylphorbol Acetate; Tumor Stem Cell Assay

2003
RING protein Trim32 associated with skin carcinogenesis has anti-apoptotic and E3-ubiquitin ligase properties.
    Carcinogenesis, 2004, Volume: 25, Issue:2

    Topics: Animals; Apoptosis; Carcinoma, Squamous Cell; Cell Division; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; Genes, p53; Head and Neck Neoplasms; Humans; Keratinocytes; Mice; Mice, Nude; RNA, Messenger; Skin Neoplasms; Skin Transplantation; Tetradecanoylphorbol Acetate; Transcription Factors; Transduction, Genetic; Tripartite Motif Proteins; Tumor Necrosis Factor-alpha; Ubiquitin-Protein Ligases; Ultraviolet Rays

2004
12-O-tetradecanoylphorbol-13-acetate and UV radiation-induced nucleoside diphosphate protein kinase B mediates neoplastic transformation of epidermal cells.
    The Journal of biological chemistry, 2004, Feb-13, Volume: 279, Issue:7

    Topics: Animals; Antigens, CD34; Arginine; Aspartic Acid; Cell Transformation, Neoplastic; Cells, Cultured; Cloning, Molecular; Culture Media, Serum-Free; DNA, Complementary; Epidermal Cells; Epidermis; Female; Gene Dosage; Glycine; Homozygote; Humans; Immunoblotting; In Situ Hybridization; Keratinocytes; Kinetics; Mice; Mutagenesis, Site-Directed; Mutation; Nucleoside-Diphosphate Kinase; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Reverse Transcriptase Polymerase Chain Reaction; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Tissue Distribution; Transfection; Ultraviolet Rays; Up-Regulation

2004
The c-Jun dimerization protein 2 inhibits cell transformation and acts as a tumor suppressor gene.
    The Journal of biological chemistry, 2004, Feb-13, Volume: 279, Issue:7

    Topics: Animals; Blotting, Western; Cell Cycle Proteins; Cell Differentiation; Cell Division; Cell Line, Tumor; Cell Separation; Cell Transformation, Neoplastic; Chick Embryo; Cyclic AMP; Cyclin D; Cyclin-Dependent Kinase Inhibitor p27; Cyclins; DNA; Fibroblasts; Flow Cytometry; Genes, Tumor Suppressor; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Mice; Mice, SCID; Muscle, Skeletal; NIH 3T3 Cells; Osteoclasts; Protein Structure, Tertiary; Repressor Proteins; Tetradecanoylphorbol Acetate; Time Factors; Transcription Factor AP-1; Transcription, Genetic; Transfection; Tumor Suppressor Proteins

2004
Inhibition of AP-1 and neoplastic transformation by fresh apple peel extract.
    The Journal of biological chemistry, 2004, Mar-12, Volume: 279, Issue:11

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Division; Cell Line; Cell Transformation, Neoplastic; Electron Spin Resonance Spectroscopy; Genes, Reporter; Hydrogen Peroxide; Hydroxyl Radical; Luciferases; Malus; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neoplasms, Experimental; Phosphorylation; Plant Extracts; Reactive Oxygen Species; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate; Time Factors; Transcription Factor AP-1; Transcriptional Activation; Transgenes; Ultraviolet Rays

2004
Adhesion, migration, transcriptional, interferon-inducible, and other signaling molecules newly implicated in cancer susceptibility and resistance of JB6 cells by cDNA microarray analyses.
    Molecular carcinogenesis, 2004, Volume: 39, Issue:1

    Topics: Animals; Antineoplastic Agents; Biomarkers, Tumor; Carcinogens; Cell Adhesion; Cell Movement; Cell Transformation, Neoplastic; Drug Resistance, Neoplasm; Gene Expression Profiling; Genetic Predisposition to Disease; Interferons; Mice; Neoplasm Proteins; Oligonucleotide Array Sequence Analysis; RNA, Messenger; RNA, Neoplasm; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription, Genetic

2004
Lipopolysaccharide enhancement of 12-o-tetradecanoylphorbol 13-acetate-mediated transformation in rat glioma C6, accompanied by induction of inducible nitric oxide synthase.
    Toxicology letters, 2004, Feb-28, Volume: 147, Issue:1

    Topics: Animals; Carcinogens; Cell Line, Tumor; Cell Survival; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Induction; Enzyme Inhibitors; Flavanones; Gene Expression; Glioma; Lipopolysaccharides; Matrix Metalloproteinase 9; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Quercetin; Rats; Tetradecanoylphorbol Acetate

2004
Nitric oxide does not mediate but inhibits transformation and tumor phenotype.
    Molecular cancer therapeutics, 2003, Volume: 2, Issue:12

    Topics: Animals; Apoptosis; Base Sequence; Cell Line; Cell Transformation, Neoplastic; DNA Primers; Mice; NF-kappa B; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Phenotype; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Transcriptional Activation; Tumor Necrosis Factor-alpha

2003
V599EB-RAF is an oncogene in melanocytes.
    Cancer research, 2004, Apr-01, Volume: 64, Issue:7

    Topics: Animals; Carcinogens; Cell Line, Tumor; Cell Transformation, Neoplastic; Female; Humans; MAP Kinase Signaling System; Melanocytes; Melanoma; Mice; Mice, Nude; Oncogenes; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-raf; Tetradecanoylphorbol Acetate; Transfection

2004
Dominant-negative c-Jun (TAM67) target genes: HMGA1 is required for tumor promoter-induced transformation.
    Oncogene, 2004, May-27, Volume: 23, Issue:25

    Topics: Animals; Butadienes; Cell Line; Cell Transformation, Neoplastic; Clone Cells; Cyclin D1; Disease Susceptibility; DNA, Complementary; Epidermal Cells; Epidermis; Gene Expression Profiling; Genes, jun; HMGA1a Protein; HMGA1b Protein; MAP Kinase Kinase Kinase 1; MAP Kinase Kinase Kinases; MAP Kinase Signaling System; Mice; Mice, Transgenic; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Nitriles; Oligonucleotide Array Sequence Analysis; Oligonucleotides, Antisense; Osteopontin; Proto-Oncogene Proteins c-jun; Sialoglycoproteins; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription, Genetic

2004
Novel p21-activated kinase-dependent protrusions characteristically formed at the edge of transformed cells.
    Experimental cell research, 2004, May-01, Volume: 295, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Actins; Animals; Calcium-Binding Proteins; Carcinogens; cdc42 GTP-Binding Protein; Cell Cycle Proteins; Cell Line, Transformed; Cell Line, Tumor; Cell Size; Cell Surface Extensions; Cell Transformation, Neoplastic; Enzyme Activation; Epithelial Cells; Guanine Nucleotide Exchange Factors; Lysophospholipids; Microscopy, Electron, Scanning; Models, Biological; p21-Activated Kinases; Protein Serine-Threonine Kinases; Rats; Rats, Inbred F344; Rho Guanine Nucleotide Exchange Factors; Tetradecanoylphorbol Acetate; Time Factors; Trachea

2004
A novel role for mixed-lineage kinase-like mitogen-activated protein triple kinase alpha in neoplastic cell transformation and tumor development.
    Cancer research, 2004, Jun-01, Volume: 64, Issue:11

    Topics: Animals; Base Sequence; Carcinogens; Cell Adhesion; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Epidermal Growth Factor; MAP Kinase Kinase Kinases; MAP Kinase Signaling System; Mice; Mice, Nude; Molecular Sequence Data; Phosphorylation; RNA, Small Interfering; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factors

2004
Early detection of alterations associated to oral cancer.
    Acta odontologica latinoamericana : AOL, 2000, Volume: 13, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Analysis of Variance; Animals; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cheek; Cricetinae; Hyperplasia; Mesocricetus; Mouth Neoplasms; Neoplasms, Radiation-Induced; Nucleolus Organizer Region; Silver Staining; Statistics, Nonparametric; Tetradecanoylphorbol Acetate

2000
Alpha 2-HS glycoprotein (fetuin-A) modulates murine skin tumorigenesis.
    International journal of oncology, 2004, Volume: 25, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; alpha-2-HS-Glycoprotein; Animals; Apoptosis; Blood Proteins; Cell Proliferation; Cell Transformation, Neoplastic; Mice; Mice, Inbred C57BL; Mutation; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate

2004
Melittin shares certain cellular effects with phorbol ester tumour promoters.
    Nature, 1979, Jul-05, Volume: 280, Issue:5717

    Topics: Animals; Arachidonic Acid; Bee Venoms; Bees; Cell Differentiation; Cell Division; Cell Line; Cell Line, Tumor; Cell Transformation, Neoplastic; Melanoma; Melitten; Mice; Prostaglandins; Tetradecanoylphorbol Acetate

1979
[Induction of human oral carcinoma by human papillomavirus 16 E6/E7 and TPA].
    Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology, 2003, Volume: 17, Issue:3

    Topics: Animals; Carcinogens; Carcinoma; Cell Transformation, Neoplastic; Cells, Cultured; Human papillomavirus 16; Humans; Mice; Mice, SCID; Mouth Neoplasms; Oncogene Proteins, Viral; Papillomavirus E7 Proteins; Papillomavirus Infections; Repressor Proteins; Tetradecanoylphorbol Acetate

2003
Delayed and sustained activation of extracellular signal-regulated kinase in human keratinocytes by UVA: implications in carcinogenesis.
    The Journal of biological chemistry, 2004, Dec-17, Volume: 279, Issue:51

    Topics: Animals; Apoptosis; Blotting, Western; Calcium; Carbazoles; Caspase 3; Caspases; Cell Line; Cell Line, Tumor; Cell Membrane; Cell Survival; Cell Transformation, Neoplastic; Chelating Agents; COS Cells; Cytosol; Dose-Response Relationship, Radiation; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; ErbB Receptors; Estrenes; Flow Cytometry; Genes, Dominant; Golgi Apparatus; Humans; Indoles; Keratinocytes; Mitogen-Activated Protein Kinase 3; Models, Biological; Neoplasms; Plasmids; Protein Kinase C; Pyrrolidinones; ras Proteins; Skin Neoplasms; Subcellular Fractions; Tetradecanoylphorbol Acetate; Time Factors; Transfection; Ultraviolet Rays

2004
Potential chemopreventive properties of extract from baked sweet potato (Ipomoea batatas Lam. Cv. Koganesengan).
    Journal of agricultural and food chemistry, 2004, Nov-17, Volume: 52, Issue:23

    Topics: Animals; Anticarcinogenic Agents; Apoptosis; Cell Line; Cell Transformation, Neoplastic; Chemoprevention; HL-60 Cells; Hot Temperature; Humans; Ipomoea batatas; Mice; Plant Extracts; Plant Tubers; Tetradecanoylphorbol Acetate

2004
An antitumorigenic role for murine 8S-lipoxygenase in skin carcinogenesis.
    Oncogene, 2005, Feb-10, Volume: 24, Issue:7

    Topics: Animals; Arachidonate Lipoxygenases; Carcinoma; Cell Line; Cell Proliferation; Cell Transformation, Neoplastic; Female; Gene Expression; Genes, Tumor Suppressor; Hydroxyeicosatetraenoic Acids; Linoleic Acids, Conjugated; Membrane Proteins; Mice; Mice, Transgenic; Papilloma; Promoter Regions, Genetic; RNA, Messenger; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transgenes

2005
Blackberry extracts inhibit activating protein 1 activation and cell transformation by perturbing the mitogenic signaling pathway.
    Nutrition and cancer, 2004, Volume: 50, Issue:1

    Topics: Antioxidants; Cell Division; Cell Line, Tumor; Cell Transformation, Neoplastic; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Fruit; Humans; Mitogen-Activated Protein Kinase Kinases; Plant Extracts; Reactive Oxygen Species; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factor AP-1

2004
Crucial role of phospholipase Cepsilon in chemical carcinogen-induced skin tumor development.
    Cancer research, 2004, Dec-15, Volume: 64, Issue:24

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Proliferation; Cell Transformation, Neoplastic; Mice; Mice, Inbred C57BL; Mutation; Phosphoinositide Phospholipase C; ras Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Type C Phospholipases

2004
The telomerase RNA component Terc is required for the tumour-promoting effects of Tert overexpression.
    EMBO reports, 2005, Volume: 6, Issue:3

    Topics: Animals; Cell Transformation, Neoplastic; Chromosomal Instability; Chromosome Aberrations; DNA-Binding Proteins; Gene Deletion; In Situ Hybridization, Fluorescence; Keratinocytes; Mice; Mice, Knockout; Mutation; Neoplasms; Protein Subunits; RNA; Skin Neoplasms; Telomerase; Tetradecanoylphorbol Acetate; Wound Healing

2005
NUP98-HOXD13 transgenic mice develop a highly penetrant, severe myelodysplastic syndrome that progresses to acute leukemia.
    Blood, 2005, Jul-01, Volume: 106, Issue:1

    Topics: Acute Disease; Animals; Carcinogens; Cell Differentiation; Cell Transformation, Neoplastic; Disease Models, Animal; Homeodomain Proteins; Humans; K562 Cells; Leukemia; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myelodysplastic Syndromes; Myeloid Ecotropic Viral Integration Site 1 Protein; Neoplasm Proteins; Nuclear Pore Complex Proteins; Penetrance; Phenotype; Severity of Illness Index; Tetradecanoylphorbol Acetate; Transcription Factors; Translocation, Genetic

2005
[Gene expression profiles in early stage of BALB/c 3T3 cells' transformation promoted with 12-O-tetradecanoylphorbol-13-acetate].
    Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine], 2005, Volume: 39, Issue:2

    Topics: Animals; Apoptosis; BALB 3T3 Cells; Cell Cycle; Cell Differentiation; Cell Proliferation; Cell Transformation, Neoplastic; Flow Cytometry; Gene Expression; Gene Expression Profiling; Methylnitronitrosoguanidine; Mice; Oligonucleotide Array Sequence Analysis; Tetradecanoylphorbol Acetate

2005
The effect of PPARgamma ligands on UV- or chemically-induced carcinogenesis in mouse skin.
    Molecular carcinogenesis, 2005, Volume: 43, Issue:4

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Proliferation; Cell Transformation, Neoplastic; Chromans; Diet; Female; Keratinocytes; Ligands; Mice; PPAR gamma; RNA, Messenger; Rosiglitazone; Skin Neoplasms; Tetradecanoylphorbol Acetate; Thiazolidinediones; Troglitazone; Ultraviolet Rays

2005
Inhibition of activator protein-1, NF-kappaB, and MAPKs and induction of phase 2 detoxifying enzyme activity by chlorogenic acid.
    The Journal of biological chemistry, 2005, Jul-29, Volume: 280, Issue:30

    Topics: Agar; Animals; Antineoplastic Agents; Antioxidants; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Chlorogenic Acid; Cytosol; DNA-Binding Proteins; Dose-Response Relationship, Drug; Electric Impedance; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Genes, Reporter; Glutathione Transferase; Humans; Immunohistochemistry; Isoenzymes; Luciferases; MAP Kinase Signaling System; Mice; NADH, NADPH Oxidoreductases; NF-E2-Related Factor 2; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Plasmids; Protein Transport; Tetradecanoylphorbol Acetate; Trans-Activators; Transcription Factor AP-1; Transcriptional Activation; Ultraviolet Rays

2005
Early growth response 1 acts as a tumor suppressor in vivo and in vitro via regulation of p53.
    Cancer research, 2005, Jun-15, Volume: 65, Issue:12

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Growth Processes; Cell Transformation, Neoplastic; Chromosome Mapping; DNA Damage; DNA-Binding Proteins; Early Growth Response Protein 1; Female; Fibroblasts; Gene Expression Profiling; Genes, Tumor Suppressor; Immediate-Early Proteins; Male; Mice; Mice, Inbred C57BL; Promoter Regions, Genetic; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factors; Tumor Suppressor Protein p53; Up-Regulation

2005
c-Fos-dependent induction of the small ras-related GTPase Rab11a in skin carcinogenesis.
    The American journal of pathology, 2005, Volume: 167, Issue:1

    Topics: Animals; Blotting, Northern; Blotting, Western; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Electrophoretic Mobility Shift Assay; Female; Fibroblasts; Fluorescent Antibody Technique; Humans; In Situ Hybridization; Keratinocytes; Mice; Mice, Transgenic; Promoter Regions, Genetic; Proto-Oncogene Proteins c-fos; rab GTP-Binding Proteins; Reverse Transcriptase Polymerase Chain Reaction; Skin Neoplasms; Tetradecanoylphorbol Acetate

2005
Chemopreventive effect of bicyclol on malignant transformation of WB-F344 rat liver epithelial cells and its effect on related signal transduction in vitro.
    Cancer letters, 2006, May-18, Volume: 236, Issue:2

    Topics: Animals; Antineoplastic Agents; Benz(a)Anthracenes; Biphenyl Compounds; Cell Communication; Cell Line; Cell Proliferation; Cell Transformation, Neoplastic; Colony-Forming Units Assay; Enzyme Induction; Epithelial Cells; I-kappa B Proteins; Liver Neoplasms; Male; Methylcholanthrene; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NF-KappaB Inhibitor alpha; Protein Kinase C-alpha; Rats; Rats, Inbred F344; Signal Transduction; Tetradecanoylphorbol Acetate

2006
Raised expression of the antiapoptotic protein ped/pea-15 increases susceptibility to chemically induced skin tumor development.
    Oncogene, 2005, Oct-27, Volume: 24, Issue:47

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Apoptosis Regulatory Proteins; Blotting, Western; Carcinogens; Caspase 3; Caspases; Cell Transformation, Neoplastic; Cells, Cultured; Cocarcinogenesis; DNA, Antisense; Enzyme Activation; Humans; Intracellular Signaling Peptides and Proteins; Keratinocytes; Male; Mice; Mice, Inbred C57BL; Mice, Nude; Mice, Transgenic; Papilloma; Phosphoproteins; Sarcoma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transfection

2005
Reduced excision repair cross-complementing 1 expression associates with enhanced papilloma formation and fibroblast transformation after genetic disruption of secreted protein acidic and rich in cysteine.
    International journal of oncology, 2005, Volume: 27, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cells, Cultured; DNA Adducts; DNA-Binding Proteins; Embryo, Mammalian; Endonucleases; Female; Fibroblasts; Gene Expression; Genotype; Male; Mice; Mice, Inbred Strains; Mice, Knockout; Osteonectin; Papilloma; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Skin; Tetradecanoylphorbol Acetate; Time Factors

2005
3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone [MX] shows initiating and promoting activities in a two-stage BALB/c 3T3 cell transformation assay.
    Mutagenesis, 2005, Volume: 20, Issue:5

    Topics: Animals; BALB 3T3 Cells; Biological Assay; Carcinogens; Cell Transformation, Neoplastic; Coculture Techniques; Furans; Mice; Tetradecanoylphorbol Acetate; Thioguanine

2005
Global genomic changes induced by two-stage carcinogen exposure are precancerous alterations in non-transformed human liver epithelial THLE-3 cells.
    International journal of oncology, 2005, Volume: 27, Issue:4

    Topics: Benzo(a)pyrene; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 17; DNA; DNA Damage; G1 Phase; Gene Expression Regulation, Neoplastic; Genome, Human; Genotype; Humans; In Situ Hybridization, Fluorescence; Laser Scanning Cytometry; Liver; Methylnitronitrosoguanidine; Neoplasms; Nucleic Acid Hybridization; Phenotype; Ploidies; Resting Phase, Cell Cycle; Tetradecanoylphorbol Acetate; Time Factors

2005
Chemopreventive effect of dimethyl dicarboxylate biphenyl on malignant transformation of WB-F344 rat liver epithelial cells.
    Acta pharmacologica Sinica, 2005, Volume: 26, Issue:11

    Topics: Animals; Antineoplastic Agents; Carcinogens; Cell Communication; Cell Transformation, Neoplastic; Cells, Cultured; Dioxoles; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Epithelial Cells; Gap Junctions; Hepatocytes; Rats; Rats, Inbred F344; Tetradecanoylphorbol Acetate

2005
Lack of expression of the EP2 but not EP3 receptor for prostaglandin E2 results in suppression of skin tumor development.
    Cancer research, 2005, Oct-15, Volume: 65, Issue:20

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogens; Cell Growth Processes; Cell Transformation, Neoplastic; Cyclic AMP; Dinoprostone; Drug Eruptions; Female; Hyperplasia; Keratinocytes; Mice; Mice, Knockout; Neovascularization, Pathologic; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP3 Subtype; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate

2005
An inter-laboratory collaborative study by the Non-Genotoxic Carcinogen Study Group in Japan, on a cell transformation assay for tumour promoters using Bhas 42 cells.
    Alternatives to laboratory animals : ATLA, 2005, Volume: 33, Issue:6

    Topics: Animal Testing Alternatives; Animals; BALB 3T3 Cells; Carcinogenicity Tests; Carcinogens; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Japan; Lithocholic Acid; Mice; Reproducibility of Results; Tetradecanoylphorbol Acetate; Time Factors

2005
PTEN loss promotes rasHa-mediated papillomatogenesis via dual up-regulation of AKT activity and cell cycle deregulation but malignant conversion proceeds via PTEN-associated pathways.
    Cancer research, 2006, Feb-01, Volume: 66, Issue:3

    Topics: Animals; Carcinogens; Cell Differentiation; Cell Transformation, Neoplastic; Keratin-13; Keratins; MAP Kinase Signaling System; Mice; Mice, Transgenic; Mifepristone; Oncogene Protein v-akt; Papilloma; PTEN Phosphohydrolase; ras Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate; Up-Regulation

2006
Mechanisms of increased expression of toll-like receptor-4 in human monocyte/macrophage-derived foam cells.
    Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 2005, Volume: 25, Issue:5

    Topics: Cell Line, Tumor; Cell Transformation, Neoplastic; Foam Cells; Gene Expression Regulation; Humans; Leukemia, Monocytic, Acute; Lipoproteins, LDL; Tetradecanoylphorbol Acetate; Toll-Like Receptor 4

2005
Deregulated minichromosomal maintenance protein MCM7 contributes to oncogene driven tumorigenesis.
    Oncogene, 2006, Jul-06, Volume: 25, Issue:29

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biomarkers, Tumor; Carcinogens; Carcinoma, Squamous Cell; Cell Cycle Proteins; Cell Proliferation; Cell Transformation, Neoplastic; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; Genes, ras; Humans; Mice; Mice, Transgenic; Minichromosome Maintenance Complex Component 7; Mutation; Neoplasm Proteins; Neoplasms, Experimental; Nuclear Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate

2006
Association of gene expression with sequential proliferation, differentiation and tumor formation in murine skin.
    Carcinogenesis, 2006, Volume: 27, Issue:8

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biomarkers; Carcinogens; Cell Differentiation; Cell Proliferation; Cell Transformation, Neoplastic; Female; Filaggrin Proteins; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genes, ras; Humans; Mice; Mice, Transgenic; Oligonucleotide Array Sequence Analysis; Papilloma; Reverse Transcriptase Polymerase Chain Reaction; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate

2006
Lipopolysaccharide plus 12-o-tetradecanoylphorbol 13-acetate induction of migration and invasion of glioma cells in vitro and in vivo: Differential inhibitory effects of flavonoids.
    Neuroscience, 2006, Jun-30, Volume: 140, Issue:2

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Carcinogens; Cell Movement; Cell Transformation, Neoplastic; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Flavanones; Flavonoids; Glioma; Humans; Kaempferols; Lipopolysaccharides; MAP Kinase Signaling System; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Nitric Oxide; Nitric Oxide Synthase; Rats; Tetradecanoylphorbol Acetate

2006
Ras mutation promotes p53 activation and apoptosis of skin keratinocytes.
    Carcinogenesis, 2006, Volume: 27, Issue:8

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogens; Cell Transformation, Neoplastic; Enzyme Inhibitors; Genes, ras; Keratinocytes; Mice; Mice, Inbred C57BL; Mitochondria; Mutation; NADPH Oxidases; Onium Compounds; Protein Transport; rac1 GTP-Binding Protein; Reactive Oxygen Species; RNA, Small Interfering; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53

2006
Identification of novel genes expressed during rhabdomyosarcoma differentiation using cDNA microarrays.
    Pathology international, 2006, Volume: 56, Issue:5

    Topics: Adult; Cell Line, Tumor; Cell Transformation, Neoplastic; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Male; Membrane Proteins; Mitochondrial Precursor Protein Import Complex Proteins; Muscle, Skeletal; Oligonucleotide Array Sequence Analysis; Protein Precursors; Reverse Transcriptase Polymerase Chain Reaction; Rhabdomyosarcoma; RNA, Messenger; RNA, Neoplasm; Saccharomyces cerevisiae Proteins; Soft Tissue Neoplasms; Tetradecanoylphorbol Acetate; Thymosin

2006
Inhibition of poly(ADP-ribose) polymerase modulates tumor-related gene expression, including hypoxia-inducible factor-1 activation, during skin carcinogenesis.
    Cancer research, 2006, Jun-01, Volume: 66, Issue:11

    Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; Hypoxia-Inducible Factor 1, alpha Subunit; Isoquinolines; Mice; Mice, Inbred C57BL; NF-kappa B; Piperidines; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Reverse Transcriptase Polymerase Chain Reaction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factor AP-1

2006
Involvement of the paxillin pathway in JB6 Cl41 cell transformation.
    Cancer research, 2006, Jun-01, Volume: 66, Issue:11

    Topics: Animals; Base Sequence; Cell Growth Processes; Cell Line; Cell Transformation, Neoplastic; Down-Regulation; Epidermal Growth Factor; MAP Kinase Kinase 4; Mice; Molecular Sequence Data; Paxillin; Phosphorylation; Proto-Oncogene Proteins c-jun; RNA, Small Interfering; Serine; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transfection

2006
Disruption of EphA2 receptor tyrosine kinase leads to increased susceptibility to carcinogenesis in mouse skin.
    Cancer research, 2006, Jul-15, Volume: 66, Issue:14

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Growth Processes; Cell Transformation, Neoplastic; Enzyme Activation; Ephrin-A1; Female; Genetic Predisposition to Disease; Keratinocytes; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Receptor, EphA2; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate

2006
Skin epidermis lacking the c-Myc gene is resistant to Ras-driven tumorigenesis but can reacquire sensitivity upon additional loss of the p21Cip1 gene.
    Genes & development, 2006, Aug-01, Volume: 20, Issue:15

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Cyclin-Dependent Kinase Inhibitor p21; Epidermis; Female; Gene Expression Regulation, Neoplastic; Genes, ras; Male; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Proto-Oncogene Proteins c-myc; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Up-Regulation

2006
Homozygous K5Cre transgenic mice have wavy hair and accelerated malignant progression in a murine model of skin carcinogenesis.
    Molecular carcinogenesis, 2007, Volume: 46, Issue:1

    Topics: Alopecia; Animals; Carcinogens; Cell Transformation, Neoplastic; Cocarcinogenesis; Disease Models, Animal; Disease Progression; DNA Damage; Female; Genes, ras; Genotype; Hair; Hair Follicle; Homozygote; Integrases; Keratin-15; Keratin-5; Keratinocytes; Male; Mammary Glands, Animal; Mice; Mice, Transgenic; Papilloma; Recombination, Genetic; Skin Neoplasms; Tetradecanoylphorbol Acetate

2007
Inhibitory effects of asiatic acid on 7,12-dimethylbenz[a]anthracene and 12-O-tetradecanoylphorbol 13-acetate-induced tumor promotion in mice.
    Biological & pharmaceutical bulletin, 2007, Volume: 30, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogens; Cell Transformation, Neoplastic; Cocarcinogenesis; Cyclooxygenase 2; Dose-Response Relationship, Drug; Enzyme Induction; Female; Mice; Mice, Inbred ICR; Nitric Oxide; Nitric Oxide Synthase Type II; Papilloma; Pentacyclic Triterpenes; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Triterpenes

2007
Pro/antioxidant status and AP-1 transcription factor in murine skin following topical exposure to cumene hydroperoxide.
    Carcinogenesis, 2007, Volume: 28, Issue:7

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzene Derivatives; Cell Line; Cell Proliferation; Cell Transformation, Neoplastic; Female; Gene Expression Regulation, Neoplastic; Glutathione; Mice; Mice, Transgenic; Oxidation-Reduction; Oxidative Stress; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factor AP-1

2007
Malignant transformation of DMBA/TPA-induced papillomas and nevi in the skin of mice selectively lacking retinoid-X-receptor alpha in epidermal keratinocytes.
    The Journal of investigative dermatology, 2007, Volume: 127, Issue:5

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Transformation, Neoplastic; Epidermis; Gene Expression Regulation, Neoplastic; Keratinocytes; Mice; Mice, Transgenic; Nevus, Pigmented; Papilloma; PPAR gamma; Retinoid X Receptor alpha; Skin Neoplasms; Tetradecanoylphorbol Acetate

2007
Peonidin inhibits phorbol-ester-induced COX-2 expression and transformation in JB6 P+ cells by blocking phosphorylation of ERK-1 and -2.
    Annals of the New York Academy of Sciences, 2007, Volume: 1095

    Topics: Animals; Anthocyanins; Antineoplastic Agents, Phytogenic; Cell Line, Transformed; Cell Transformation, Neoplastic; Cyclooxygenase 2 Inhibitors; Growth Inhibitors; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Protein Kinase Inhibitors; Tetradecanoylphorbol Acetate

2007
Dual role of inactivating Lef1 mutations in epidermis: tumor promotion and specification of tumor type.
    Cancer research, 2007, Apr-01, Volume: 67, Issue:7

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma, Sebaceous; Animals; Cell Transformation, Neoplastic; Cocarcinogenesis; Cyclin-Dependent Kinase Inhibitor p21; Epidermis; Female; Genes, ras; Lymphoid Enhancer-Binding Factor 1; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Transgenic; Mutation; Sebaceous Gland Neoplasms; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53

2007
SAG/ROC2/Rbx2 is a novel activator protein-1 target that promotes c-Jun degradation and inhibits 12-O-tetradecanoylphorbol-13-acetate-induced neoplastic transformation.
    Cancer research, 2007, Apr-15, Volume: 67, Issue:8

    Topics: Binding Sites; Carrier Proteins; Cell Transformation, Neoplastic; Cloning, Molecular; Consensus Sequence; Doublecortin Protein; Gene Expression Regulation, Neoplastic; Gene Silencing; HeLa Cells; Humans; Promoter Regions, Genetic; Proto-Oncogene Proteins c-jun; RNA-Binding Proteins; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Ubiquitin-Protein Ligases; Ubiquitins

2007
[Expression of mitochondrial ferritin in K562 leukemic cell during TPA-induced cell differentiation].
    Zhongguo shi yan xue ye xue za zhi, 2007, Volume: 15, Issue:2

    Topics: Antigens, CD; Cell Proliferation; Cell Transformation, Neoplastic; Ferritins; Humans; Iron-Regulatory Proteins; K562 Cells; Mitochondria; Receptors, Transferrin; RNA, Messenger; Tetradecanoylphorbol Acetate

2007
Expression profile of skin papillomas with high cancer risk displays a unique genetic signature that clusters with squamous cell carcinomas and predicts risk for malignant conversion.
    Oncogene, 2007, Oct-18, Volume: 26, Issue:48

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biomarkers, Tumor; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Female; Gene Expression Profiling; Immunity, Cellular; Immunophenotyping; Mice; Mice, Inbred SENCAR; Oligonucleotide Array Sequence Analysis; Papilloma; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; Risk Factors; RNA, Messenger; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate

2007
Redox effector factor-1, combined with reactive oxygen species, plays an important role in the transformation of JB6 cells.
    Carcinogenesis, 2007, Volume: 28, Issue:11

    Topics: Animals; Annexin A5; Apoptosis; Base Sequence; Cadmium Chloride; Cell Line; Cell Transformation, Neoplastic; DNA Damage; DNA-(Apurinic or Apyrimidinic Site) Lyase; Hydrogen Peroxide; Mice; Oxidative Stress; Reactive Oxygen Species; RNA, Small Interfering; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Ultraviolet Rays

2007
The effect of cyclooxygenase-2 overexpression on skin carcinogenesis is context dependent.
    Molecular carcinogenesis, 2007, Volume: 46, Issue:12

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anthralin; Blotting, Northern; Blotting, Western; Carcinogens; Cell Proliferation; Cell Transformation, Neoplastic; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclooxygenase 2; Dermatologic Agents; Drug Resistance, Neoplasm; Female; Humans; Interleukin-1alpha; Mice; Mice, Transgenic; Ornithine Decarboxylase; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

2007
Decreased c-kit function inhibits enhanced skin carcinogenesis in c-Ha-ras protooncogene transgenic mice.
    Cancer science, 2007, Volume: 98, Issue:10

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Blotting, Western; Carcinogens; Cell Transformation, Neoplastic; Female; Genes, ras; Humans; Male; Mast Cells; Mice; Mice, Inbred C57BL; Mice, Transgenic; Papilloma; Polymerase Chain Reaction; Promoter Regions, Genetic; Proto-Oncogene Proteins c-kit; Proto-Oncogene Proteins p21(ras); Skin Neoplasms; Tetradecanoylphorbol Acetate; Transgenes

2007
Myricetin is a novel natural inhibitor of neoplastic cell transformation and MEK1.
    Carcinogenesis, 2007, Volume: 28, Issue:9

    Topics: Animals; Antineoplastic Agents; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Enzyme Inhibitors; Epidermal Growth Factor; Fireflies; Flavonoids; Genes, Reporter; Luciferases; MAP Kinase Kinase 1; Mice; Recombinant Proteins; Tetradecanoylphorbol Acetate

2007
Expression of the human Cathepsin L inhibitor hurpin in mice: skin alterations and increased carcinogenesis.
    Experimental dermatology, 2007, Volume: 16, Issue:9

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogens; Cathepsin L; Cathepsins; Cell Transformation, Neoplastic; Cysteine Endopeptidases; Humans; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Transgenic; Microarray Analysis; Serpins; Skin; Tetradecanoylphorbol Acetate; Ultraviolet Rays

2007
The role of glycogen synthase kinase 3beta in the transformation of epidermal cells.
    Cancer research, 2007, Aug-15, Volume: 67, Issue:16

    Topics: Animals; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Enzyme Activation; Epidermal Growth Factor; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Male; Mice; Mice, Inbred BALB C; Oncogene Protein v-akt; Phosphatidylinositol 3-Kinases; Protein Kinase C; Signal Transduction; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transfection

2007
Forced expression of a constitutively active form of Stat3 in mouse epidermis enhances malignant progression of skin tumors induced by two-stage carcinogenesis.
    Oncogene, 2008, Feb-14, Volume: 27, Issue:8

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Cell Line, Tumor; Cell Transformation, Neoplastic; Disease Models, Animal; Disease Progression; Epidermis; Keratinocytes; Mice; Mice, Transgenic; Skin Neoplasms; STAT3 Transcription Factor; Tetradecanoylphorbol Acetate

2008
Ribosomal S6 kinase 2 is a key regulator in tumor promoter induced cell transformation.
    Cancer research, 2007, Sep-01, Volume: 67, Issue:17

    Topics: Animals; Base Sequence; Carcinogens; Cell Adhesion; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; Epidermal Growth Factor; G1 Phase; Mice; Molecular Sequence Data; NIH 3T3 Cells; Ribosomal Protein S6 Kinases, 90-kDa; Sequence Homology, Nucleic Acid; Tetradecanoylphorbol Acetate; Transfection

2007
SAG/ROC2 E3 ligase regulates skin carcinogenesis by stage-dependent targeting of c-Jun/AP1 and IkappaB-alpha/NF-kappaB.
    The Journal of cell biology, 2007, Sep-10, Volume: 178, Issue:6

    Topics: Animals; Cell Proliferation; Cell Transformation, Neoplastic; Enzyme Activation; Epidermis; Humans; I-kappa B Proteins; Mice; Mice, Transgenic; NF-kappa B; NF-KappaB Inhibitor alpha; Proto-Oncogene Proteins c-jun; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Ubiquitin-Protein Ligases

2007
Heat shock factor 1 is a powerful multifaceted modifier of carcinogenesis.
    Cell, 2007, Sep-21, Volume: 130, Issue:6

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; DNA-Binding Proteins; Fibroblasts; Gene Expression Regulation, Neoplastic; Genotype; Glucose; Heat Shock Transcription Factors; Humans; Methylnitronitrosoguanidine; Mice; Mice, Inbred BALB C; Mice, Knockout; Mutation; Phenotype; Protein Biosynthesis; Proto-Oncogene Proteins c-sis; ras Proteins; RNA Interference; RNA, Small Interfering; Signal Transduction; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Transcription Factors; Transduction, Genetic; Tumor Suppressor Protein p53

2007
Cdk2 deficiency decreases ras/CDK4-dependent malignant progression, but not myc-induced tumorigenesis.
    Cancer research, 2007, Oct-15, Volume: 67, Issue:20

    Topics: Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Disease Progression; Enzyme Activation; Female; Male; Mice; Mice, Transgenic; Proto-Oncogene Proteins c-myc; ras Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate

2007
Prevention of skin tumorigenesis and impairment of epidermal cell proliferation by targeted aquaporin-3 gene disruption.
    Molecular and cellular biology, 2008, Volume: 28, Issue:1

    Topics: Adenosine Triphosphate; Animals; Aquaporin 3; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; Epidermis; Glycerol; Humans; Keratinocytes; Mice; Mice, Knockout; Neoplasms, Squamous Cell; Skin Neoplasms; Tetradecanoylphorbol Acetate

2008
Hmga1 null mice are less susceptible to chemically induced skin carcinogenesis.
    European journal of cancer (Oxford, England : 1990), 2008, Volume: 44, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Transformation, Neoplastic; Genetic Predisposition to Disease; HMGA Proteins; Keratinocytes; Mice; Mice, Knockout; Papilloma; Proto-Oncogene Proteins c-fos; rab GTP-Binding Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate

2008
A JNK1/AP-1-dependent, COX-2 induction is implicated in 12-O-tetradecanoylphorbol-13-acetate-induced cell transformation through regulating cell cycle progression.
    Molecular cancer research : MCR, 2008, Volume: 6, Issue:1

    Topics: Animals; Cell Cycle; Cell Transformation, Neoplastic; Cyclooxygenase 2; Enzyme Induction; Fibroblasts; Humans; I-kappa B Kinase; Mice; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinase 9; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription Factor RelA

2008
Raf and MEK protein kinases are direct molecular targets for the chemopreventive effect of quercetin, a major flavonol in red wine.
    Cancer research, 2008, Feb-01, Volume: 68, Issue:3

    Topics: Animals; Anticarcinogenic Agents; Antioxidants; Cell Transformation, Neoplastic; Cells, Cultured; MAP Kinase Kinase 1; Mice; NF-kappa B; Proto-Oncogene Proteins c-raf; Quercetin; Resveratrol; Skin; Skin Neoplasms; Stilbenes; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcriptional Activation; Wine

2008
Translation inhibitor Pdcd4 is targeted for degradation during tumor promotion.
    Cancer research, 2008, Mar-01, Volume: 68, Issue:5

    Topics: Animals; Apoptosis Regulatory Proteins; Cell Transformation, Neoplastic; Disease Progression; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Transgenic; Proteasome Endopeptidase Complex; Ribosomal Protein S6 Kinases, 70-kDa; RNA-Binding Proteins; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate

2008
Fucoidan from Laminaria cichorioides inhibits AP-1 transactivation and cell transformation in the mouse epidermal JB6 cells.
    Molecular carcinogenesis, 2008, Volume: 47, Issue:8

    Topics: Animals; Cell Adhesion; Cell Line; Cell Transformation, Neoplastic; Epidermal Cells; Epidermal Growth Factor; Laminaria; MAP Kinase Signaling System; Mice; Phosphorylation; Polysaccharides; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcriptional Activation

2008
The influence of diesel exhaust on polycyclic aromatic hydrocarbon-induced DNA damage, gene expression, and tumor initiation in Sencar mice in vivo.
    Cancer letters, 2008, Jun-28, Volume: 265, Issue:1

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Cell Transformation, Neoplastic; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; DNA Adducts; DNA Damage; Mice; Mice, Inbred SENCAR; Particulate Matter; Polycyclic Aromatic Hydrocarbons; Skin Neoplasms; Tetradecanoylphorbol Acetate; Vehicle Emissions

2008
Mitogen- and stress-activated kinase 1-mediated histone H3 phosphorylation is crucial for cell transformation.
    Cancer research, 2008, Apr-01, Volume: 68, Issue:7

    Topics: Animals; Cell Growth Processes; Cell Transformation, Neoplastic; Enzyme Activation; Epidermal Growth Factor; G1 Phase; Histones; Isoquinolines; Mice; Phosphorylation; Protein Kinase Inhibitors; Ribosomal Protein S6 Kinases, 90-kDa; RNA, Small Interfering; Skin; Sulfonamides; Tetradecanoylphorbol Acetate; Transcription Factor AP-1

2008
Polymeric black tea polyphenols inhibit mouse skin chemical carcinogenesis by decreasing cell proliferation.
    Cell proliferation, 2008, Volume: 41, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Cell Nucleus; Cell Proliferation; Cell Transformation, Neoplastic; Cyclin-Dependent Kinase Inhibitor p21; Enzyme Activation; Epidermis; Female; Flavonoids; Inflammation Mediators; MAP Kinase Signaling System; Mice; Ornithine Decarboxylase; Phenols; Polymers; Polyphenols; Precancerous Conditions; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Skin Neoplasms; Tea; Tetradecanoylphorbol Acetate; Transcription Factors; Tumor Suppressor Protein p53

2008
Stage-specific disruption of Stat3 demonstrates a direct requirement during both the initiation and promotion stages of mouse skin tumorigenesis.
    Carcinogenesis, 2008, Volume: 29, Issue:6

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Blotting, Western; Carcinogens; Cell Transformation, Neoplastic; Immunohistochemistry; Mice; Mice, Transgenic; Polymerase Chain Reaction; Signal Transduction; Skin Neoplasms; STAT3 Transcription Factor; Tamoxifen; Tetradecanoylphorbol Acetate

2008
Reduced susceptibility to two-stage skin carcinogenesis in mice with low circulating insulin-like growth factor I levels.
    Cancer research, 2008, May-15, Volume: 68, Issue:10

    Topics: Animals; Benz(a)Anthracenes; Cell Proliferation; Cell Transformation, Neoplastic; Epidermis; Female; Genetic Predisposition to Disease; Insulin-Like Growth Factor I; Mice; Models, Biological; Neoplasms; Protein Kinases; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; TOR Serine-Threonine Kinases

2008
Changes in genomic imprinting and gene expression associated with transformation in a model of human osteosarcoma.
    Experimental and molecular pathology, 2008, Volume: 84, Issue:3

    Topics: Bone Neoplasms; Carcinogens; Cell Line; Cell Transformation, Neoplastic; DNA Methylation; Gene Expression Regulation, Neoplastic; Genomic Imprinting; Humans; Methylnitronitrosoguanidine; Oligonucleotide Array Sequence Analysis; Osteoblasts; Osteosarcoma; Tetradecanoylphorbol Acetate

2008
Effect of an anticancer agent, vinblastine, on mouse skin.
    Toxicology letters, 1984, Volume: 22, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Cell Transformation, Viral; Female; Herpesvirus 4, Human; Hyperplasia; Mice; Skin; Tetradecanoylphorbol Acetate; Vinblastine; Virus Activation

1984
Differentiation of chronic lymphocytic leukemia cells after in vitro treatment with Epstein-Barr virus or phorbol ester. I. Immunologic and morphologic studies.
    American journal of hematology, 1984, Volume: 17, Issue:4

    Topics: Aged; Antibody-Producing Cells; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cytoplasm; Female; Herpesvirus 4, Human; Humans; Immunoglobulins; Leukemia, Lymphoid; Lymphocyte Activation; Male; Middle Aged; Phorbols; Tetradecanoylphorbol Acetate

1984
Promoter-induced cellular responses closely correlated with the enhancement of cell transformation.
    Princess Takamatsu symposia, 1983, Volume: 14

    Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; ErbB Receptors; Lyngbya Toxins; Methylcholanthrene; Mice; Phorbol Esters; Receptors, Cell Surface; Tetradecanoylphorbol Acetate

1983
The study of tumor promotion in a cell culture model for mouse skin--a tissue that exhibits multistage carcinogenesis in vivo.
    Carcinogenesis; a comprehensive survey, 1982, Volume: 7

    Topics: Animals; Carcinogens; Cell Differentiation; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Clone Cells; Cocarcinogenesis; Enzyme Induction; Epidermis; gamma-Glutamyltransferase; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate

1982
Enhancement by TPA of phenotypes associated with transformation in carcinogen-treated human cells: evidence for a selective mechanism.
    International journal of cancer, 1983, Oct-15, Volume: 32, Issue:4

    Topics: Cell Aggregation; Cell Transformation, Neoplastic; Cells, Cultured; Cocarcinogenesis; Culture Media; Female; gamma-Glutamyltransferase; Humans; Methylnitronitrosoguanidine; Phenotype; Phorbols; Tetradecanoylphorbol Acetate; Uterus

1983
Regulation of epidermal transglutaminase activity and terminal differentiation by retinoids and phorbol esters.
    Cancer research, 1983, Volume: 43, Issue:12 Pt 1

    Topics: Acyltransferases; Animals; Animals, Newborn; Cell Transformation, Neoplastic; Cells, Cultured; Enzyme Induction; Kinetics; Mice; Mice, Inbred BALB C; Phorbols; Protein Biosynthesis; Retinoids; Skin; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transglutaminases; Tretinoin

1983
Phorbol ester tumor promoter modulation of alloantigen-specific T lymphocyte responses.
    Journal of immunology (Baltimore, Md. : 1950), 1982, Volume: 129, Issue:1

    Topics: Cell Separation; Cell Transformation, Neoplastic; Cytotoxicity, Immunologic; Epitopes; Flow Cytometry; HLA Antigens; Humans; Interferon Inducers; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Phorbols; T-Lymphocytes; Tetradecanoylphorbol Acetate

1982
Modifiers of free radicals inhibit in vitro the oncogenic actions of x-rays, bleomycin, and the tumor promoter 12-O-tetradecanoylphorbol 13-acetate.
    Proceedings of the National Academy of Sciences of the United States of America, 1983, Volume: 80, Issue:5

    Topics: Animals; Bleomycin; Carcinogens; Catalase; Cell Transformation, Neoplastic; Cricetinae; Embryo, Nonmammalian; Female; Free Radicals; Mesocricetus; Phorbols; Pregnancy; Superoxide Dismutase; Tetradecanoylphorbol Acetate

1983
A subpopulation of cultured human keratinocytes which is resistant to the induction of terminal differentiation-related changes by phorbol, 12-myristate, 13-acetate: evidence for an increase in the resistant population following transformation.
    Carcinogenesis, 1983, Volume: 4, Issue:7

    Topics: Animals; Carcinoma, Squamous Cell; Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Child; Cholera Toxin; Epidermal Growth Factor; Female; Fetus; Humans; Hydrocortisone; Keratins; Male; Mice; Phorbols; Pregnancy; Simian virus 40; Skin; Skin Physiological Phenomena; Tetradecanoylphorbol Acetate

1983
Functional maturation of membrane potential changes and superoxide-producing capacity during differentiation of human granulocytes.
    The Journal of clinical investigation, 1984, Volume: 73, Issue:4

    Topics: Adult; Calcimycin; Cell Differentiation; Cell Transformation, Neoplastic; Deoxyglucose; Dimethyl Sulfoxide; Gramicidin; Granulocytes; Humans; Leukemia, Myeloid; Membrane Potentials; Phagocytosis; Superoxides; Tetradecanoylphorbol Acetate; Tretinoin

1984
Non-promoting hyperplasiogenic agents do not mimic the effects of phorbol, 12-myristate, 13-acetate on terminal differentiation of normal and transformed human keratinocytes.
    Carcinogenesis, 1984, Volume: 5, Issue:5

    Topics: Alkynes; Calcimycin; Carcinoma, Squamous Cell; Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Clone Cells; Humans; Hyperplasia; Keratins; Phorbols; Skin; Tetradecanoylphorbol Acetate

1984
Differential effects of complete and second-stage tumour promoters in normal but not transformed human and mouse keratinocytes.
    Carcinogenesis, 1984, Volume: 5, Issue:8

    Topics: Carcinogens; Carcinoma, Squamous Cell; Cell Line; Cell Transformation, Neoplastic; Diterpenes; Drug Resistance; Epidermal Cells; Epidermis; Humans; Keratins; Phorbol Esters; Phorbols; Terpenes; Tetradecanoylphorbol Acetate

1984
Effects of 12-O-tetradecanoylphorbol-13-acetate on fibroblasts from individuals genetically predisposed to cancer.
    Cancer research, 1982, Volume: 42, Issue:9

    Topics: Cell Adhesion; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cytoskeleton; Disease Susceptibility; Down Syndrome; Epidermal Growth Factor; Fanconi Anemia; Female; Fibroblasts; Humans; Intestinal Polyps; Male; Neoplasms; Phorbols; Tetradecanoylphorbol Acetate; Trypsin; Xeroderma Pigmentosum

1982
Phorbol ester-induced changes in human leukemic pre-B lines.
    Cellular immunology, 1984, Volume: 84, Issue:1

    Topics: Antigens, Neoplasm; B-Lymphocytes; Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; Humans; Immunoglobulin mu-Chains; Leukemia; Leukemia, Lymphoid; Neprilysin; Phorbols; Stem Cells; Tetradecanoylphorbol Acetate

1984
Tumor promoters: an overview of membrane-associated alterations and intracellular events.
    Transplantation proceedings, 1984, Volume: 16, Issue:2

    Topics: Animals; Carcinogens; Cell Membrane; Cell Nucleus; Cell Transformation, Neoplastic; Cells, Cultured; DNA Replication; Fibroblasts; Mice; Protein Kinase C; Protein Kinases; Tetradecanoylphorbol Acetate

1984
Changes in epidermal growth factor receptors associated with adenovirus transformation, chemical carcinogen transformation and exposure to a phorbol ester tumor promoter.
    Biochemical and biophysical research communications, 1980, Apr-29, Volume: 93, Issue:4

    Topics: Adenoviruses, Human; Animals; Carcinogens; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Epidermal Growth Factor; Mice; Peptides; Phorbols; Rats; Receptors, Cell Surface; Tetradecanoylphorbol Acetate

1980
Factors which disorganize microtubules or microfilaments increase the frequency of cell transformation by polyoma virus.
    Journal of virology, 1980, Volume: 36, Issue:2

    Topics: Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Colchicine; Cytochalasin B; Epidermal Growth Factor; Griseofulvin; Melitten; Mutagens; Podophyllotoxin; Polyomavirus; Tetradecanoylphorbol Acetate; Vinblastine

1980
The modulating effect of retinoids and a tumor promoter on malignant transformation, sister chromatid exchanges, and Na/K ATPase.
    Annals of the New York Academy of Sciences, 1981, Feb-27, Volume: 359

    Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Crossing Over, Genetic; Mice; Mice, Inbred C3H; Phorbols; Sister Chromatid Exchange; Sodium-Potassium-Exchanging ATPase; Tetradecanoylphorbol Acetate; Vitamin A

1981
Specific binding of transforming growth factor correlates with promotion of anchorage independence in EGF receptorless mouse JB6 cells.
    Biochemical and biophysical research communications, 1981, Sep-30, Volume: 102, Issue:2

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Clone Cells; Epidermal Growth Factor; ErbB Receptors; Humans; Mice; Peptides; Receptors, Cell Surface; Skin; Tetradecanoylphorbol Acetate; Transforming Growth Factors

1981
Synergistic effects of cigarette smoke extracts, benz (a) pyrene and nickel sulphate on morphological transformation of hamster embryo cells.
    Developments in toxicology and environmental science, 1980, Volume: 8

    Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Cell Transformation, Neoplastic; Cells, Cultured; Cocarcinogenesis; Cricetinae; Embryo, Mammalian; Mesocricetus; Nickel; Smoking; Tetradecanoylphorbol Acetate

1980
Modulation of human T-cell differentiation markers by 12-O-tetradecanoylphorbol-13-acetate.
    Thymus, 1981, Volume: 3, Issue:4-5

    Topics: 5'-Nucleotidase; Adenosine Deaminase; Adult; Animals; Cell Transformation, Neoplastic; Colony-Forming Units Assay; Cytarabine; DNA; DNA Nucleotidylexotransferase; Histocompatibility Antigens Class II; Humans; Leukemia, Experimental; Nucleotidases; Phorbols; Phytohemagglutinins; Rosette Formation; Sheep; T-Lymphocytes; Tetradecanoylphorbol Acetate

1981
Equivalency of endothelial cell growth supplement to irradiated feeder cells in carcinogen-induced morphologic transformation of Syrian hamster embryo cells.
    Journal of the National Cancer Institute, 1982, Volume: 68, Issue:1

    Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Cell Line; Cell Transformation, Neoplastic; Cocarcinogenesis; Cricetinae; Cytological Techniques; Embryo, Mammalian; Growth Substances; Lymphotoxin-alpha; Mesocricetus; Tetradecanoylphorbol Acetate; Ultraviolet Rays

1982
Dexamethasone synergistically induces chemotactic peptide receptor expression in HL-60 cells.
    Blood, 1982, Volume: 59, Issue:3

    Topics: Cell Line; Cell Transformation, Neoplastic; Dexamethasone; Dimethyl Sulfoxide; Dimethylformamide; Dose-Response Relationship, Drug; Drug Synergism; Humans; Indomethacin; Methionine; Methyltestosterone; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Oligopeptides; Progesterone; Receptors, Cell Surface; Receptors, Formyl Peptide; Receptors, Steroid; Tetradecanoylphorbol Acetate; Tretinoin

1982
Reversal of the promotional effect of 12-O-tetradecanoylphorbol-13-acetate on morphological transformation of hamster embryo cells by glucocorticoids.
    Cancer letters, 1982, Volume: 15, Issue:2

    Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Cell Line; Cell Transformation, Neoplastic; Cocarcinogenesis; Corticosterone; Cricetinae; Dexamethasone; Embryo, Mammalian; Glucocorticoids; Hydrocortisone; Mesocricetus; Phorbols; Tetradecanoylphorbol Acetate

1982
Fibrinolytic activity and morphological transformation of hamster embryo cells.
    Carcinogenesis, 1982, Volume: 3, Issue:6

    Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Embryo, Mammalian; Fibrinolysis; Mesocricetus; Plasminogen Activators; Protease Inhibitors; Tetradecanoylphorbol Acetate

1982
Epstein-Barr virus induced proteins V: comparison of EBV-specific polypeptides from different virus strains.
    Medical microbiology and immunology, 1982, Volume: 171, Issue:1

    Topics: Animals; Antigens, Viral; Burkitt Lymphoma; Capsid Proteins; Cell Transformation, Neoplastic; Chlorocebus aethiops; Glycoproteins; Herpesvirus 4, Human; Humans; Molecular Weight; Peptide Biosynthesis; Peptides; Tetradecanoylphorbol Acetate

1982
Promotional effect of different phorbol esters on morphological transformation of hamster embryo cells.
    Cancer letters, 1982, Volume: 17, Issue:1

    Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Clone Cells; Cricetinae; Embryo, Mammalian; Mesocricetus; Phorbol Esters; Phorbols; Tetradecanoylphorbol Acetate

1982
Role of plasma fibronectin in the morphological transformation of hamster embryo cells.
    Cancer letters, 1982, Volume: 17, Issue:1

    Topics: Animals; Benzo(a)pyrene; Benzoates; Benzopyrenes; Cell Movement; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Embryo, Mammalian; Fibronectins; Mesocricetus; Tetradecanoylphorbol Acetate

1982
The presence of p53 transformation-related protein in Ab-MuLV transformed cells is required for their development into lethal tumors in mice.
    International journal of cancer, 1983, Mar-15, Volume: 31, Issue:3

    Topics: Abelson murine leukemia virus; Animals; Cell Line; Cell Transformation, Neoplastic; Cocarcinogenesis; Female; Leukemia Virus, Murine; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Phorbols; Phosphoproteins; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53

1983
Nutritional and hormonal factors in the prevention of carcinogen-induced neoplastic development in vitro.
    Cancer detection and prevention, 1981, Volume: 4, Issue:1-4

    Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Mice; Sister Chromatid Exchange; Sodium-Potassium-Exchanging ATPase; Tetradecanoylphorbol Acetate; Thyroid Hormones; Vitamin A

1981
Teleocidin is not mitogenic for 12-O-tetradecanoylphorbol-13-acetate non-proliferative variants of 3T3 cells.
    Carcinogenesis, 1983, Volume: 4, Issue:4

    Topics: Alkaloids; Animals; Carcinogens; Cell Division; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; Epidermal Growth Factor; ErbB Receptors; Genetic Variation; Lyngbya Toxins; Mice; Phorbols; Receptors, Cell Surface; Tetradecanoylphorbol Acetate

1983
Expression of transformed morphology and anchorage independent growth of hamster embryo cells.
    Carcinogenesis, 1983, Volume: 4, Issue:7

    Topics: Agar; Animals; Benzo(a)pyrene; Benzopyrenes; Cell Adhesion; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cricetinae; Culture Media; Embryo, Mammalian; Neoplasms, Experimental; Teratoma; Tetradecanoylphorbol Acetate

1983
Alteration of phenotype of 'regressor' avian sarcoma cells following treatment with phorbol ester.
    Cancer letters, 1983, Volume: 19, Issue:3

    Topics: Animals; Avian Sarcoma Viruses; Cell Transformation, Neoplastic; Chick Embryo; Chickens; Female; Fibroblasts; Fluorescent Antibody Technique; Male; Phenotype; Phorbols; Sarcoma, Avian; Tetradecanoylphorbol Acetate

1983
1 alpha,25-Dihydroxyvitamin D3 markedly enhances chemically-induced transformation in BALB 3T3 cells.
    Gan, 1983, Volume: 74, Issue:5

    Topics: Animals; Calcitriol; Cell Transformation, Neoplastic; Cells, Cultured; Cytosol; Dose-Response Relationship, Drug; Methylcholanthrene; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Protein Binding; Receptors, Calcitriol; Receptors, Steroid; Tetradecanoylphorbol Acetate

1983
Calcium ionophore A-23187 and 12-O-tetradecanoyl-phorbol-13-acetate stimulation of prostaglandin synthesis in herpes simplex virus type 2-transformed rat cells.
    Cancer research, 1984, Volume: 44, Issue:4

    Topics: Animals; Calcimycin; Cell Division; Cell Transformation, Neoplastic; Clone Cells; Dinoprost; Dinoprostone; Embryo, Mammalian; Fibrosarcoma; Kinetics; Neoplasm Metastasis; Phorbols; Prostaglandins; Prostaglandins E; Prostaglandins F; Rats; Simplexvirus; Tetradecanoylphorbol Acetate

1984
Gamma-interferon induces expression of the HLA-D antigens on normal and leukemic human myeloid cells.
    Proceedings of the National Academy of Sciences of the United States of America, 1984, Volume: 81, Issue:13

    Topics: B-Lymphocytes; Calcitriol; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Deltaretrovirus; Genes, MHC Class II; Histocompatibility Antigens Class II; Humans; Interferon Type I; Leukemia, Myeloid, Acute; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate

1984
Effects of nickel sulfate on growth and differentiation of normal human bronchial epithelial cells.
    Carcinogenesis, 1984, Volume: 5, Issue:12

    Topics: Bronchi; Cell Division; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Epidermal Growth Factor; Epithelium; Humans; In Vitro Techniques; Nickel; Tetradecanoylphorbol Acetate

1984
Accessory function and interleukin 1 production by human leukemic cell lines.
    Journal of immunology (Baltimore, Md. : 1950), 1984, Volume: 132, Issue:6

    Topics: Cell Line; Cell Transformation, Neoplastic; Histocompatibility Antigens Class II; HLA-DR Antigens; Humans; Interleukin-1; Isoelectric Focusing; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lymphocyte Activation; Lymphocyte Cooperation; Lymphoma, Large B-Cell, Diffuse; Monocytes; Phenotype; Phytohemagglutinins; T-Lymphocytes; Tetradecanoylphorbol Acetate

1984
Carcinogen-induced phenotypic alterations in mammary epithelial cells accompanying the development of neoplastic transformation.
    Cancer research, 1983, Volume: 43, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Epithelium; Female; Mammary Glands, Animal; Phenotype; Rats; Rats, Inbred Strains; Tamoxifen; Tetradecanoylphorbol Acetate

1983
On the persistence of tumor initiation in two-stage carcinogenesis on mouse skin.
    Carcinogenesis, 1983, Volume: 4, Issue:6

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Age Factors; Animals; Cell Transformation, Neoplastic; Male; Mice; Skin Neoplasms; Tetradecanoylphorbol Acetate

1983
Glycosyltransferase alterations are cell type related when human promyelocytic leukemia (HL-60) cells are treated with various inducers of differentiation.
    Experimental hematology, 1983, Volume: 11, Issue:8

    Topics: Cell Line; Cell Transformation, Neoplastic; Decarboxylation; Deoxyglucose; Dimethyl Sulfoxide; Fucosyltransferases; Galactosyltransferases; Hexosyltransferases; Humans; Leukemia, Myeloid, Acute; Sialyltransferases; Substrate Specificity; Tetradecanoylphorbol Acetate; Tretinoin

1983
Acute effects of 12-O-tetradecanoylphorbol-13-acetate, teleocidin B, or 2,3,7,8-tetrachlorodibenzo-p-dioxin on cultured normal human bronchial epithelial cells.
    Carcinogenesis, 1984, Volume: 5, Issue:2

    Topics: Alkaloids; Bronchi; Carcinogens; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Dioxins; DNA Replication; Epithelium; Humans; Kinetics; Lyngbya Toxins; Phorbols; Polychlorinated Dibenzodioxins; Tetradecanoylphorbol Acetate; Transcription, Genetic

1984
Active oxygen acts as a promoter of transformation in mouse embryo C3H/10T1/2/C18 fibroblasts.
    Proceedings of the National Academy of Sciences of the United States of America, 1984, Volume: 81, Issue:7

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Benzopyrenes; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Fibroblasts; Gamma Rays; Mice; Mice, Inbred C3H; Oxygen; Tetradecanoylphorbol Acetate; Xanthine; Xanthine Oxidase; Xanthines

1984
The role of protein phosphorylation at tyrosine in transformation and mitogenesis.
    Journal of cellular physiology. Supplement, 1984, Volume: 3

    Topics: Alpharetrovirus; Animals; Cell Transformation, Neoplastic; Cell Transformation, Viral; Diglycerides; Fluorescent Antibody Technique; Molecular Weight; Oncogene Protein pp60(v-src); Phosphoproteins; Phosphorylation; Protein Kinases; Protein-Tyrosine Kinases; Retroviridae; Tetradecanoylphorbol Acetate; Viral Proteins

1984
Characterization of a transformation-sensitive protein in the extracellular matrix of chicken embryo fibroblasts.
    The Journal of biological chemistry, 1984, Sep-25, Volume: 259, Issue:18

    Topics: Animals; Cell Transformation, Neoplastic; Chick Embryo; Culture Media; Egtazic Acid; Extracellular Matrix; Fibroblasts; Lactoperoxidase; Molecular Weight; Proteins; Tetradecanoylphorbol Acetate

1984
Suppression of the first stage of phorbol 12-tetradecanoate 13-acetate-effected tumor promotion in mouse skin by nontoxic inhibition of DNA synthesis.
    Proceedings of the National Academy of Sciences of the United States of America, 1984, Volume: 81, Issue:18

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; DNA Replication; Female; Hydroxyurea; Mice; Mice, Inbred Strains; Phorbol Esters; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate

1984
Oncogene-induced transformation of C3H 10T1/2 cells is enhanced by tumor promoters.
    Science (New York, N.Y.), 1984, Nov-02, Volume: 226, Issue:4674

    Topics: Animals; Carcinogens; Cell Line; Cell Transformation, Neoplastic; DNA, Neoplasm; Humans; Lyngbya Toxins; Mice; Mice, Inbred C3H; Oncogenes; Tetradecanoylphorbol Acetate; Transfection

1984
The proliferative response of low-density human cell cultures to tumor promoters and its relevance to carcinogenic mechanisms in vitro.
    International journal of cancer, 1984, Dec-15, Volume: 34, Issue:6

    Topics: Caenorhabditis elegans Proteins; Carcinogens; Carrier Proteins; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Diterpenes; Fibroblasts; Humans; Lyngbya Toxins; Protein Kinase C; Receptors, Drug; Receptors, Immunologic; Terpenes; Tetradecanoylphorbol Acetate

1984
Studies on the action of tumour promoters and antipromoters on respiratory-tract epithelium.
    IARC scientific publications, 1984, Issue:56

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Epithelial Cells; Epithelium; Humans; Methylnitronitrosoguanidine; Mice; Rats; Respiratory Tract Neoplasms; Tetradecanoylphorbol Acetate; Trachea; Tracheal Neoplasms

1984
Stages of tumour promotion in skin.
    IARC scientific publications, 1984, Issue:56

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Aging; Animals; Animals, Newborn; Carcinogens; Cell Division; Cell Transformation, Neoplastic; Hyperplasia; Mice; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Wounds and Injuries

1984
Enhancement of primate retrovirus synthesis by tumour promoters.
    IARC scientific publications, 1984, Issue:56

    Topics: Carcinogens; Cell Line; Cell Transformation, Neoplastic; DNA Replication; Female; Humans; Kidney; Leukemia, Lymphoid; Lyngbya Toxins; Ovarian Neoplasms; Phorbols; Retroviridae; Rhabdomyosarcoma; Species Specificity; Tetradecanoylphorbol Acetate; Virus Replication

1984
Modulation of chronic lymphocytic leukemia cells by phorbol ester: increase in Ia expression, IgM secretion and MLR stimulatory capacity.
    Journal of immunology (Baltimore, Md. : 1950), 1982, Volume: 128, Issue:5

    Topics: Aged; Animals; Binding Sites, Antibody; Cell Transformation, Neoplastic; Dose-Response Relationship, Immunologic; Female; Histocompatibility Antigens Class II; Humans; Immunoglobulin M; Leukemia, Lymphoid; Lymphocyte Culture Test, Mixed; Mice; Mice, Inbred A; Phorbols; Rabbits; Receptors, Antigen, B-Cell; Tetradecanoylphorbol Acetate

1982
In vitro modulation of oncogenesis and differentiation by retinoids and tumor promoters.
    Carcinogenesis; a comprehensive survey, 1982, Volume: 7

    Topics: Adenosine Triphosphatases; Animals; Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Cocarcinogenesis; Cricetinae; Embryo, Mammalian; Mice; Phorbols; Retinol-Binding Proteins; Sister Chromatid Exchange; Tetradecanoylphorbol Acetate; Tretinoin; X-Rays

1982
Transformation and tumor promoter sensitive phosphoproteins in JB-6 mouse epidermal cells: one is also sensitive to heat stress.
    Carcinogenesis, 1984, Volume: 5, Issue:9

    Topics: Animals; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Epidermis; Hot Temperature; Mice; Molecular Weight; Phosphoproteins; Phosphorylation; Proteins; Tetradecanoylphorbol Acetate

1984
Chronic application of a tumor promoter to confluent nontransformed rat cells induces the irreversible expression of transformed phenotype.
    Oncology, 1984, Volume: 41, Issue:5

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Clone Cells; Female; Phenotype; Phorbols; Pregnancy; Rats; Rats, Inbred F344; Tetradecanoylphorbol Acetate; Time Factors

1984
The transformation of a rat cell line induced by a tumor promoter occurs without affecting sister chromatid exchange.
    Oncology, 1984, Volume: 41, Issue:5

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Crossing Over, Genetic; Female; Phenotype; Phorbols; Pregnancy; Rats; Rats, Inbred F344; Sister Chromatid Exchange; Tetradecanoylphorbol Acetate

1984
Susceptibility of skin fibroblasts from individuals genetically predisposed to cancer, to transformation by the tumour promoter 12-O-tetradecanoylphorbol-13-acetate.
    International journal of cancer, 1984, Sep-15, Volume: 34, Issue:3

    Topics: Adult; Animals; Cell Division; Cell Line; Cell Movement; Cell Transformation, Neoplastic; Cells, Cultured; Child; Child, Preschool; Colonic Polyps; Eye Neoplasms; Female; Fetus; Fibroblasts; Humans; Infant; Male; Mice; Mice, Nude; Middle Aged; Neoplasm Transplantation; Phorbols; Pregnancy; Retinoblastoma; Skin; Tetradecanoylphorbol Acetate; Transplantation, Heterologous

1984
Role of free radicals in the initiation and promotion of radiation transformation in vitro.
    Carcinogenesis, 1984, Volume: 5, Issue:10

    Topics: Animals; Catalase; Cell Transformation, Neoplastic; Free Radicals; Hydrogen Peroxide; Mice; Salicylates; Superoxide Dismutase; Tetradecanoylphorbol Acetate

1984
Effects of agents known to antagonize the enhancement of in vitro transformation by 12-tetradecanoyl-phorbol-13-acetate (TPA) on the TPA suppression of metabolic cooperation.
    Cancer letters, 1984, Volume: 25, Issue:2

    Topics: Animals; Antipain; Cell Communication; Cell Line; Cell Transformation, Neoplastic; Cricetinae; Oligopeptides; Phorbols; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Tretinoin; Trypsin Inhibitors

1984
Role of specific membrane and genetic changes in the mechanism of tumour promotion. Studies with promoter-resistant variants.
    IARC scientific publications, 1984, Issue:56

    Topics: Animals; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Clone Cells; DNA, Neoplasm; Drug Resistance; Gangliosides; Genes; Genetic Variation; Mice; Rats; Skin; Tetradecanoylphorbol Acetate; Transfection

1984
Modulation by retinyl acetate of microfilament bundle formation in C3H/10T1/2 cells.
    Journal of cellular biochemistry, 1984, Volume: 24, Issue:1

    Topics: Actins; Animals; Cell Adhesion; Cell Line; Cell Transformation, Neoplastic; Cytoskeleton; Diterpenes; Mice; Microscopy, Electron; Retinyl Esters; Tetradecanoylphorbol Acetate; Vitamin A

1984
Induction of cytotoxic effector activity in the HL-60 promyelocytic cell line by incubation with phorbol myristate acetate: a model system of human spontaneous monocyte-mediated cytotoxicity.
    Cellular immunology, 1983, Feb-15, Volume: 76, Issue:1

    Topics: Animals; Antimetabolites; Cell Line; Cell Transformation, Neoplastic; Cellobiose; Chickens; Cytotoxicity, Immunologic; Disaccharides; Humans; Kinetics; Leukemia, Myeloid, Acute; Models, Biological; Monocytes; Tetradecanoylphorbol Acetate

1983
Differentiation of HL-60 cells: cell volume and cell cycle changes.
    Cytometry, 1983, Volume: 3, Issue:6

    Topics: Butyrates; Butyric Acid; Cell Count; Cell Cycle; Cell Transformation, Neoplastic; Dimethyl Sulfoxide; Flow Cytometry; Humans; Leukemia, Myeloid, Acute; Macrophages; Tetradecanoylphorbol Acetate; Tretinoin

1983
Nonspecific esterases of leukemia cell lines: evidence for activation of myeloid-associated zymogens in HL-60 by phorbol esters.
    Blood, 1984, Volume: 63, Issue:1

    Topics: Cell Line; Cell Transformation, Neoplastic; Enzyme Activation; Enzyme Precursors; Esterases; Humans; Isoenzymes; Leukemia, Myeloid; Phorbols; Tetradecanoylphorbol Acetate

1984
Phenotypic modulation of chronic lymphocytic leukemia cells by phorbol ester: induction of IgM secretion and changes in the expression of B cell-associated surface antigens.
    Journal of immunology (Baltimore, Md. : 1950), 1984, Volume: 132, Issue:1

    Topics: Antigens, Neoplasm; Antigens, Surface; B-Lymphocytes; Cell Differentiation; Cell Transformation, Neoplastic; Humans; Immunoglobulin M; Kinetics; Leukemia, Lymphoid; Phenotype; Phorbols; Receptors, Antigen, B-Cell; Tetradecanoylphorbol Acetate

1984
Alteration of the chemotactic response of NIH/3T3 cells to PDGF by growth factors, transformation, and tumor promoters.
    Cell, 1984, Volume: 36, Issue:2

    Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Chemotaxis; Epidermal Growth Factor; Epithelium; Fibroblast Growth Factors; Fibroblasts; Growth Substances; Kirsten murine sarcoma virus; Mice; Phorbols; Platelet-Derived Growth Factor; Tetradecanoylphorbol Acetate

1984
Inhibition of radiation-initiated and -promoted transformation of Syrian hamster embryo cells by lymphotoxin.
    Cancer research, 1984, Volume: 44, Issue:4

    Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Embryo, Mammalian; Galactose; Kinetics; Lymphotoxin-alpha; Mesocricetus; Tetradecanoylphorbol Acetate

1984
Reduced trisialoganglioside synthesis in chemically but not mos-transformed mouse epidermal cells.
    Cancer research, 1984, Volume: 44, Issue:4

    Topics: Animals; Carbon Radioisotopes; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Diterpenes; Epidermal Growth Factor; Gangliosides; Glucosamine; Mice; Phorbol Esters; Phorbols; Skin; Terpenes; Tetradecanoylphorbol Acetate

1984
Partial purification and characterization of a BCGFII from EL4 culture supernatants.
    Journal of immunology (Baltimore, Md. : 1950), 1984, Volume: 132, Issue:5

    Topics: Animals; B-Lymphocytes; Cell Line; Cell Transformation, Neoplastic; Chromatography, Gel; Chromatography, Ion Exchange; Growth Substances; Interleukin-4; Isoelectric Focusing; Kinetics; Lymphocyte Activation; Lymphokines; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Tetradecanoylphorbol Acetate

1984
The effects of tumor-promoting phorbol esters on human granulopoiesis in vitro.
    Blood, 1984, Volume: 64, Issue:2

    Topics: Bone Marrow; Bone Marrow Cells; Cell Transformation, Neoplastic; Colony-Forming Units Assay; Colony-Stimulating Factors; Granulocytes; Hematopoiesis; Hematopoietic Stem Cells; Humans; Macrophages; Monocytes; Phorbol Esters; Phorbols; Tetradecanoylphorbol Acetate

1984
Distinctive phorbol ester-induced morphological and surface antigen changes in mycosis fungoides, the Sézary syndrome, and adult T-cell leukemia.
    Cancer research, 1984, Volume: 44, Issue:8

    Topics: Adult; Antigens, Surface; Cell Transformation, Neoplastic; Cells, Cultured; Humans; Kinetics; Leukemia; Mycosis Fungoides; Phenotype; Phorbols; Sezary Syndrome; T-Lymphocytes; Tetradecanoylphorbol Acetate

1984
Factors that modify in vitro transformation.
    Progress in clinical and biological research, 1983, Volume: 132B

    Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Culture Media; Humans; Mesocricetus; Mice; Phytohemagglutinins; Tetradecanoylphorbol Acetate

1983
Malignant transformation of epithelial cells in culture.
    Progress in clinical and biological research, 1983, Volume: 132B

    Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Chromosome Aberrations; Epithelium; Humans; Mice; Skin; Tetradecanoylphorbol Acetate

1983
Transfer of phorbol ester promotability by transfection of DNA from promotable into nonpromotable cells.
    Progress in nucleic acid research and molecular biology, 1983, Volume: 29

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Mice; Mice, Inbred BALB C; Phorbols; Skin; Tetradecanoylphorbol Acetate; Transfection

1983
In vitro studies of the possible mechanisms whereby tumour promoters mediate their responses.
    Princess Takamatsu symposia, 1983, Volume: 14

    Topics: Carcinogens; Cell Movement; Cell Transformation, Neoplastic; Cells, Cultured; Chromosome Aberrations; Colonic Neoplasms; Eye Neoplasms; Fibroblasts; Humans; Methylnitronitrosoguanidine; Mutation; Retinoblastoma; Skin; Tetradecanoylphorbol Acetate

1983
Enhanced sensitivity of the C3H/10T1/2 cell transformation system to alkylating and chemotherapeutic agents by treatment with 12-O-tetradecanoylphorbol-13-acetate.
    Environmental mutagenesis, 1984, Volume: 6, Issue:1

    Topics: Alkylating Agents; Animals; Antineoplastic Agents; Cell Transformation, Neoplastic; Cells, Cultured; Fibroblasts; Mice; Phorbols; Tetradecanoylphorbol Acetate

1984
Transformation of cultured epithelial cells by ethylnitrosourea. Altered expression of type I procollagen chains.
    Biochimica et biophysica acta, 1984, Mar-23, Volume: 803, Issue:3

    Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Epithelium; Ethylnitrosourea; Kinetics; Macromolecular Substances; Molecular Weight; Nitrosourea Compounds; Peptides; Procollagen; Rats; Tetradecanoylphorbol Acetate

1984
[Effect of tumor promoting agents on the in vitro malignant transformation of the fetal rat brain cells exposed in utero to ethylnitrosourea].
    No to shinkei = Brain and nerve, 1984, Volume: 36, Issue:2

    Topics: Animals; Brain Neoplasms; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Drug Interactions; Ethylnitrosourea; Female; Fetus; In Vitro Techniques; Maternal-Fetal Exchange; Nitrosourea Compounds; Phenobarbital; Phorbols; Pregnancy; Rats; Tetradecanoylphorbol Acetate

1984
Properties of cell lots suitable for focus assay in the chemical transformation of Syrian hamster cells in culture.
    Gan, 1980, Volume: 71, Issue:5

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Drug Evaluation, Preclinical; Mesocricetus; Tetradecanoylphorbol Acetate

1980
Protease inhibitor antipain suppresses 12-O-tetradecanoyl-phorbol-13-acetate induction of plasminogen activator in transformable mouse embryo fibroblasts.
    Carcinogenesis, 1981, Volume: 2, Issue:9

    Topics: Animals; Antipain; Cell Transformation, Neoplastic; Cells, Cultured; Enzyme Induction; Female; Fibroblasts; Leupeptins; Mice; Oligopeptides; Phorbols; Plasminogen Activators; Plasminogen Inactivators; Pregnancy; Tetradecanoylphorbol Acetate; Time Factors; Trypsin Inhibitor, Bowman-Birk Soybean

1981
Effects of teleocidin and the phorbol ester tumor promoters on cell transformation, differentiation, and phospholipid metabolism.
    Cancer research, 1982, Volume: 42, Issue:7

    Topics: Adenoviruses, Human; Alkaloids; Animals; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Choline; Humans; Lyngbya Toxins; Melanins; Melanoma; Mice; Muscles; Phorbols; Phospholipids; Rats; Tetradecanoylphorbol Acetate

1982
Initiation of C3H/10T1/2 cell transformation by N-methyl-N'-nitro-N-nitrosoguanidine and aflatoxin B1.
    Carcinogenesis, 1982, Volume: 3, Issue:4

    Topics: Aflatoxin B1; Aflatoxins; Animals; Cell Line; Cell Transformation, Neoplastic; Methylcholanthrene; Methylnitronitrosoguanidine; Mice; Tetradecanoylphorbol Acetate

1982
TPA affects early and late stages of chemically-induced transformation in mouse submandibular salivary epithelial cells in vitro.
    Carcinogenesis, 1983, Volume: 4, Issue:1

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Dimethyl Sulfoxide; Epithelial Cells; Epithelium; Male; Mice; Phenotype; Phorbols; Submandibular Gland; Tetradecanoylphorbol Acetate; Thymidine; Time Factors

1983
Hexose uptake as an indicator of JB6 mouse epidermal cell resistance to the mitogenic activity of TPA.
    Journal of cellular physiology, 1983, Volume: 114, Issue:2

    Topics: Animals; Biological Transport, Active; Cell Division; Cell Line; Cell Transformation, Neoplastic; Deoxy Sugars; Deoxyglucose; Drug Resistance; Epidermis; Interphase; Kinetics; Mice; Mitogens; Phorbols; Tetradecanoylphorbol Acetate

1983
The nuclear-associated endoplasmic reticulum is an early target for the action of the tumor promoter 12-O-tetradecanoyl phorbol-13-acetate in C3H/10T1/2 fibroblasts.
    FEBS letters, 1983, Feb-07, Volume: 152, Issue:1

    Topics: Animals; Cell Nucleus; Cell Transformation, Neoplastic; Cells, Cultured; Choline; Endoplasmic Reticulum; Intracellular Membranes; Membrane Lipids; Mice; Phorbols; Tetradecanoylphorbol Acetate

1983
Prevention of hereditary large bowel cancer: tissue culture assays and logistics.
    Progress in clinical and biological research, 1983, Volume: 115

    Topics: Actins; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Colonic Neoplasms; Humans; Oncogenic Viruses; Rectal Neoplasms; Tetradecanoylphorbol Acetate

1983
Increased DNA content as an early marker of transformation in carcinogen-exposed rat tracheal cell cultures.
    Carcinogenesis, 1983, Volume: 4, Issue:6

    Topics: Aneuploidy; Animals; Cell Transformation, Neoplastic; DNA; Interphase; Male; Methylnitronitrosoguanidine; Rats; Rats, Inbred F344; Tetradecanoylphorbol Acetate; Trachea

1983
Factors influencing the promotion of transformation in chemically-initiated C3H/10T1/2 Cl 8 mouse embryo fibroblasts.
    Carcinogenesis, 1983, Volume: 4, Issue:6

    Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Female; Fibroblasts; Methylnitronitrosoguanidine; Mice; Mice, Inbred C3H; Phorbols; Pregnancy; Tetradecanoylphorbol Acetate; Time Factors

1983
Growth stimulation and tumor promotion in skin.
    The Journal of investigative dermatology, 1983, Volume: 81, Issue:1 Suppl

    Topics: Animals; Cell Division; Cell Transformation, Neoplastic; Mice; Phorbol Esters; Phorbols; Prostaglandins; Skin; Tetradecanoylphorbol Acetate

1983
Transformation of epidermal cells in culture.
    The Journal of investigative dermatology, 1983, Volume: 81, Issue:1 Suppl

    Topics: Animals; Calcium; Cell Transformation, Neoplastic; Cells, Cultured; DNA Replication; Epidermal Cells; Epidermis; Mice; Mice, Inbred BALB C; Tetradecanoylphorbol Acetate

1983
Ornithine decarboxylase activity and DNA synthesis in primary and transformed hamster epidermal cells exposed to tumor promoter.
    Cancer research, 1983, Volume: 43, Issue:9

    Topics: Animals; Animals, Newborn; Carboxy-Lyases; Cell Cycle; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; DNA Replication; Kinetics; Mesocricetus; Ornithine Decarboxylase; Phorbols; Skin; Tetradecanoylphorbol Acetate

1983
Ornithine decarboxylase induction by chemically complex liquids from two solvent refined coal processes.
    Carcinogenesis, 1983, Volume: 4, Issue:7

    Topics: Animals; Carboxy-Lyases; Cell Transformation, Neoplastic; Coal; Enzyme Induction; Female; Kinetics; Mice; Ornithine Decarboxylase; Skin; Solvents; Tetradecanoylphorbol Acetate

1983
Onion and garlic oils inhibit tumor promotion.
    Carcinogenesis, 1983, Volume: 4, Issue:8

    Topics: Animals; Cell Transformation, Neoplastic; Drug Antagonism; Female; Garlic; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Oils; Phorbols; Plants, Medicinal; Skin Neoplasms; Tetradecanoylphorbol Acetate

1983
Role of intercellular communication in the promotion of C3H/10T1/2 cell transformation.
    Carcinogenesis, 1983, Volume: 4, Issue:9

    Topics: Animals; Cell Communication; Cell Transformation, Neoplastic; Cells, Cultured; Dose-Response Relationship, Drug; Kinetics; Mice; Mice, Inbred C3H; Phorbols; Ribonucleotides; Tetradecanoylphorbol Acetate; Transcription, Genetic; Uridine

1983
Transfer of sensitivity to tumor promoters by transfection of DNA from sensitive into insensitive mouse JB6 epidermal cells.
    Molecular and cellular biology, 1983, Volume: 3, Issue:7

    Topics: Animals; Cell Adhesion; Cell Transformation, Neoplastic; Clone Cells; DNA; Mice; Phenotype; Skin; Tetradecanoylphorbol Acetate; Transfection

1983
Differentiation of human leukemias in response to 12-0-tetradecanoylphorbol-13-acetate in vitro.
    Blood, 1980, Volume: 55, Issue:5

    Topics: Cell Adhesion; Cell Aggregation; Cell Transformation, Neoplastic; Esterases; Humans; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Phagocytosis; Phorbols; Tetradecanoylphorbol Acetate

1980
Decreased membrane fluidity during differentiation of human promyelocytic leukemia cells in culture.
    Blood, 1980, Volume: 56, Issue:2

    Topics: Cell Membrane; Cell Transformation, Neoplastic; Cells, Cultured; Cholesterol; Dimethyl Sulfoxide; Humans; Leukemia, Myeloid, Acute; Membrane Lipids; Phospholipids; Tetradecanoylphorbol Acetate

1980
Early changes in phosphatidylcholine metabolism in human acute promyelocytic leukemia cells stimulated to differentiate by phorbol ester.
    Blood, 1981, Volume: 58, Issue:2

    Topics: Cell Transformation, Neoplastic; Humans; Leukemia, Myeloid, Acute; Methylation; Phorbol Esters; Phorbols; Phosphatidylcholines; Phospholipids; Tetradecanoylphorbol Acetate; Time Factors

1981
Retinoids inhibit promoter-dependent preneoplastic progression in mouse epidermal cell lines.
    Annals of the New York Academy of Sciences, 1981, Feb-27, Volume: 359

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Mice; Phorbols; Skin; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Tretinoin

1981
Modulation of terminal differentiation and responses to tumor promoters by retinoids in mouse epidermal cell cultures.
    Annals of the New York Academy of Sciences, 1981, Feb-27, Volume: 359

    Topics: Animals; Cell Differentiation; Cell Division; Cell Line; Cell Transformation, Neoplastic; Enzyme Induction; Mice; Ornithine Decarboxylase; Phorbols; Skin; Tetradecanoylphorbol Acetate; Tretinoin

1981
Terminal differentiation surface antigens of myelomonocytic cells are expressed in human promyelocytic leukemia cells (HL60) treated with chemical inducers.
    Blood, 1981, Volume: 58, Issue:4

    Topics: Animals; Antibodies, Monoclonal; Antigens, Surface; Blood Cells; Bone Marrow; Bone Marrow Cells; Cell Transformation, Neoplastic; Dimethyl Sulfoxide; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Mice; Rabbits; Tetradecanoylphorbol Acetate; Tretinoin

1981
Dissociation of mitogenesis and late-stage promotion of tumor cell phenotype by phorbol esters: mitogen-resistant variants are sensitive to promotion.
    Proceedings of the National Academy of Sciences of the United States of America, 1981, Volume: 78, Issue:11

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Clone Cells; Colchicine; Drug Resistance; Genetic Variation; Mice; Mitogens; Phenotype; Phorbols; Skin; Tetradecanoylphorbol Acetate

1981
Release of platelet-activating factor from HL-60 human leukemic cells following macrophage-like differentiation.
    Blood, 1982, Volume: 59, Issue:1

    Topics: Cell Line; Cell Transformation, Neoplastic; Humans; Leukemia, Myeloid, Acute; Leukocytes; Lysophosphatidylcholines; Macrophages; Platelet Activating Factor; Receptors, Complement; Tetradecanoylphorbol Acetate

1982
Resting state depth and saturation density as modulated by tumor promoters and culture conditions: relationship to chemical transformation in C3H/10T1/2 cells.
    Journal of the National Cancer Institute, 1982, Volume: 68, Issue:2

    Topics: Animals; Carcinogens; Cell Count; Cell Cycle; Cell Line; Cell Transformation, Neoplastic; Mice; Mice, Inbred C3H; Phorbols; Saccharin; Tetradecanoylphorbol Acetate

1982
Ganglioside changes induced by tumor promoters in promotable JB6 mouse epidermal cells: antagonism by an antipromoter.
    Journal of the National Cancer Institute, 1982, Volume: 68, Issue:3

    Topics: Animals; Cell Division; Cell Line; Cell Transformation, Neoplastic; Epidermis; Gangliosides; Mice; Phorbols; Tetradecanoylphorbol Acetate; Time Factors; Tretinoin

1982
Tumor-promoter-resistant cells lack trisialoganglioside response.
    Proceedings of the National Academy of Sciences of the United States of America, 1982, Volume: 79, Issue:16

    Topics: Animals; Cell Adhesion; Cell Division; Cell Line; Cell Transformation, Neoplastic; Drug Resistance; Gangliosides; Membrane Fluidity; Mice; Phorbol Esters; Phorbols; Tetradecanoylphorbol Acetate

1982
Inhibition by tumor-promoting phorbol esters of procollagen synthesis in promotable JB6 mouse epidermal cells.
    Journal of the National Cancer Institute, 1982, Volume: 69, Issue:5

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Epidermis; Mice; Phorbol Esters; Phorbols; Procollagen; Tetradecanoylphorbol Acetate; Tretinoin

1982
Variant cell lines from the human promyelocyte line HL60.
    Leukemia research, 1982, Volume: 6, Issue:4

    Topics: Cell Division; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Clone Cells; Dimethyl Sulfoxide; Humans; Karyotyping; Leukemia, Myeloid, Acute; Microscopy, Electron; Phenotype; Tetradecanoylphorbol Acetate

1982
Modulation of phagocytosis by tumor promoters and epidermal growth factor in normal and transformed macrophages.
    Cancer research, 1980, Volume: 40, Issue:4

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Diterpenes; Epidermal Growth Factor; Erythrocytes; Female; In Vitro Techniques; Macrophages; Mice; Microscopy, Electron, Scanning; Peptides; Phagocytosis; Phorbols; Pyran Copolymer; Tetradecanoylphorbol Acetate; Thioglycolates

1980
Regulation of gene expression by tumor promoters. II. Control of cell shape and developmental programs for macrophages and granulocytes in human myeloid leukemic cells.
    International journal of cancer, 1981, Sep-15, Volume: 28, Issue:3

    Topics: Carcinogens; Cell Line; Cell Transformation, Neoplastic; Colony-Stimulating Factors; Cytoplasm; Dimethyl Sulfoxide; Gene Expression Regulation; Granulocytes; Humans; Leukemia, Myeloid; Macrophages; Neoplasm Proteins; Tetradecanoylphorbol Acetate

1981
Neutrophil migration inhibition factor from T lymphocytes (NIF-T): selective removal of biologic activity by human peripheral blood neutrophils, myelocytic leukemia cells, and differentiated HL-60 cells.
    Journal of immunology (Baltimore, Md. : 1950), 1982, Volume: 128, Issue:1

    Topics: Animals; Cell Line; Cell Membrane; Cell Movement; Cell Transformation, Neoplastic; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Formaldehyde; Horses; Humans; Isoelectric Focusing; Leukemia, Myeloid; Lymphokines; Mice; Mice, Inbred Strains; Neutrophils; Rabbits; T-Lymphocytes; Tetradecanoylphorbol Acetate

1982
Expression of initiated and promoted stages of irradiation carcinogenesis in vitro.
    Cancer letters, 1981, Volume: 14, Issue:3

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Cocarcinogenesis; Cricetinae; Embryo, Mammalian; Lymphotoxin-alpha; Mesocricetus; Neoplasms, Radiation-Induced; Phenotype; Tetradecanoylphorbol Acetate; Time Factors; Ultraviolet Rays; X-Rays

1981
Promotion of x-ray transformation in vitro.
    Carcinogenesis; a comprehensive survey, 1982, Volume: 7

    Topics: Animals; Anti-Inflammatory Agents; Cell Count; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cocarcinogenesis; DNA Repair; Epidermal Growth Factor; Mice; Mitomycins; Mutation; Phorbols; Radiation, Ionizing; Tetradecanoylphorbol Acetate; X-Rays

1982
Studies on antagonistic actions of TPA and retinoic acid.
    Carcinogenesis; a comprehensive survey, 1982, Volume: 7

    Topics: Animals; Cell Adhesion; Cell Division; Cell Line; Cell Transformation, Neoplastic; Clone Cells; Contact Inhibition; Epidermal Growth Factor; Mice; Phorbols; Tetradecanoylphorbol Acetate; Tretinoin

1982
Lymphotoxin enhances the susceptibility of neoplastic and preneoplastic cells to natural killer cell mediated destruction.
    International journal of cancer, 1982, Apr-15, Volume: 29, Issue:4

    Topics: Animals; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cytotoxicity, Immunologic; Guinea Pigs; Humans; Immunity, Innate; Killer Cells, Natural; Leukocytes; Lymphotoxin-alpha; Precancerous Conditions; Tetradecanoylphorbol Acetate

1982
A phorbol ester tumor promoter induces changes in the expression of immunoglobulins and DR antigens in human lymphoblastoid cells.
    Journal of immunology (Baltimore, Md. : 1950), 1982, Volume: 129, Issue:2

    Topics: Antibody-Producing Cells; B-Lymphocytes; Cell Line; Cell Transformation, Neoplastic; Histocompatibility Antigens Class II; HLA-DR Antigens; Humans; Immunoglobulin D; Immunoglobulin M; Immunoglobulins; Lymphocyte Activation; Phorbols; Receptors, Antigen, B-Cell; Tetradecanoylphorbol Acetate

1982
The effect of lentinan on production of interleukin-1 by human monocytes.
    Immunopharmacology, 1982, Volume: 5, Issue:1

    Topics: Adjuvants, Immunologic; Animals; Cell Transformation, Neoplastic; Humans; Interleukin-1; Lentinan; Leukemia, Myeloid; Lymphocyte Activation; Mice; Mice, Inbred C3H; Monocytes; Phytohemagglutinins; Polysaccharides; T-Lymphocytes; Tetradecanoylphorbol Acetate

1982
Phytohemagglutinin inhibits phorbol diester promotion of UV-irradiation initiated transformation in Syrian hamster embryo cells.
    International journal of cancer, 1982, Dec-15, Volume: 30, Issue:6

    Topics: Agglutinins; Animals; Cell Transformation, Neoplastic; Concanavalin A; Cricetinae; Galactose; Leukocytes; Lymphotoxin-alpha; Neoplasms, Radiation-Induced; Phorbols; Phytohemagglutinins; Tetradecanoylphorbol Acetate

1982
Selective effects of phorbol 12-myristate 13-acetate on myofibrils and 10-nm filaments.
    Proceedings of the National Academy of Sciences of the United States of America, 1980, Volume: 77, Issue:9

    Topics: Animals; Cell Transformation, Neoplastic; Chick Embryo; Fluorescent Antibody Technique; Microscopy, Fluorescence; Muscles; Myofibrils; Myosin Subfragments; Phorbols; Tetradecanoylphorbol Acetate

1980
Differential response of premalignant epithelial cell classes to phorbol ester tumor promoters and to deoxycholic acid.
    Cancer research, 1981, Volume: 41, Issue:11 Pt 1

    Topics: Cell Division; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Colonic Neoplasms; Deoxycholic Acid; DNA Replication; Epithelium; Humans; Peptide Hydrolases; Phorbols; Plasminogen Activators; Precancerous Conditions; Protease Inhibitors; Tetradecanoylphorbol Acetate

1981
On deciding which factors regulate cell growth.
    Progress in clinical and biological research, 1981, Volume: 66 Pt A

    Topics: Animals; Caffeine; Cell Cycle; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Cycloheximide; Epidermal Growth Factor; Humans; Insulin; Kinetics; Lectins; Mutation; Tetradecanoylphorbol Acetate; Thrombin

1981
Phorbol ester-induced differentiation of a non-T, non-B leukemic cell line: model for human lymphoid progenitor cell development.
    Journal of immunology (Baltimore, Md. : 1950), 1982, Volume: 128, Issue:3

    Topics: Adolescent; Antibodies, Monoclonal; Antigens, Neoplasm; Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; DNA Nucleotidylexotransferase; Female; Fluorescent Antibody Technique; Histocompatibility Antigens Class II; Humans; Leukemia, Lymphoid; Lymphocytes; Phenotype; Phorbols; Tetradecanoylphorbol Acetate

1982
Cell competence for industion of differentiation by insulin and other compounds in myeloid leukemic clones continuously cultured in serum-free medium.
    Blood, 1982, Volume: 60, Issue:1

    Topics: Animals; Cell Differentiation; Cell Transformation, Neoplastic; Clone Cells; Colony-Stimulating Factors; Culture Media; Dexamethasone; Hematopoietic Stem Cells; Insulin; Leukemia, Myeloid; Mice; Mice, Inbred Strains; Muramidase; Tetradecanoylphorbol Acetate; Transferrin

1982
Enhanced transformation of mouse 10T1/2 cells by 12-O-tetradecanoylphorbol-13-acetate following exposure to X-rays or to fission-spectrum neutrons.
    Cancer research, 1982, Volume: 42, Issue:2

    Topics: Animals; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Cocarcinogenesis; Fast Neutrons; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Neoplasms, Radiation-Induced; Neutrons; Phorbols; Radiation Dosage; Tetradecanoylphorbol Acetate; X-Rays

1982
Effects of tumor-promoting phorbol diesters on neoplastic progression of Syrian hamster embryo cells.
    Cancer research, 1982, Volume: 42, Issue:4

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Cricetinae; Embryo, Mammalian; Mesocricetus; Neoplasms, Experimental; Ornithine Decarboxylase; Phorbol Esters; Phorbols; Polyamines; Precancerous Conditions; Tetradecanoylphorbol Acetate

1982
Effects of retinoic acid and tumor promoter 12-o-tetradecanoylphorbol-13-acetate (TPA) on the cell cycle of HeLa cells.
    International journal of cancer, 1982, Jan-15, Volume: 29, Issue:1

    Topics: Cell Cycle; Cell Division; Cell Transformation, Neoplastic; DNA; Drug Interactions; Flow Cytometry; HeLa Cells; Humans; Mitosis; Phorbols; Tetradecanoylphorbol Acetate; Thymidine; Tretinoin

1982
Derangement of regulation of protein degradation in transforming fibroblasts.
    Bioscience reports, 1982, Volume: 2, Issue:2

    Topics: Animals; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Fibroblasts; Kinetics; Mice; Proteins; Tetradecanoylphorbol Acetate

1982
The role of mitogenic stimulation and specific glycoprotein changes in the mechanism of late-stage promotion in JB-6 epidermal cell lines.
    Carcinogenesis; a comprehensive survey, 1982, Volume: 7

    Topics: Animals; Cell Adhesion; Cell Line; Cell Transformation, Neoplastic; Epidermis; Mice; Mitogens; Phorbols; Procollagen; Tetradecanoylphorbol Acetate; Tretinoin

1982
Genetic forms of neoplasia in man: a model for the study of tumor promotion in vitro.
    Carcinogenesis; a comprehensive survey, 1982, Volume: 7

    Topics: Adenoma; Bile Acids and Salts; Cell Adhesion; Cell Cycle; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Cocarcinogenesis; DNA; Dose-Response Relationship, Drug; Fibroblasts; Humans; Intestinal Neoplasms; Mutation; Phorbols; Skin; Tetradecanoylphorbol Acetate; Thymidine

1982
Regulation of mammalian cell transformation.
    Carcinogenesis; a comprehensive survey, 1982, Volume: 7

    Topics: Animals; Antipain; Caffeine; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Cocarcinogenesis; Cricetinae; DNA Repair; Lymphokines; Methylnitronitrosoguanidine; Mutation; Sister Chromatid Exchange; Tetradecanoylphorbol Acetate; Ultraviolet Rays; X-Rays

1982
Tumor promotion by regenerative epidermal hyperplasia in mouse skin.
    Journal of cutaneous pathology, 1982, Volume: 9, Issue:1

    Topics: Animals; Cell Transformation, Neoplastic; Hyperplasia; Mice; Regeneration; Skin; Skin Neoplasms; Skin Physiological Phenomena; Tetradecanoylphorbol Acetate

1982
Isolation of methylcholanthrene-"initiated" C3H/10T1/2 cells by inhibiting neoplastic progression with retinyl acetate.
    Carcinogenesis, 1982, Volume: 3, Issue:3

    Topics: Animals; Cell Line; Cell Separation; Cell Transformation, Neoplastic; Cocarcinogenesis; Contact Inhibition; Diterpenes; Methylcholanthrene; Mice; Mice, Inbred C3H; Mice, Nude; Neoplasm Transplantation; Retinyl Esters; Tetradecanoylphorbol Acetate; Vitamin A

1982
Inhibition of respiration by a phorbol ester tumor promoter in murine cultured cells.
    Biochemical and biophysical research communications, 1982, Apr-14, Volume: 105, Issue:3

    Topics: Animals; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cell Line; Cell Transformation, Neoplastic; Embryo, Mammalian; Fibroblasts; Methylcholanthrene; Mice; Mice, Inbred C3H; Oligomycins; Oxygen Consumption; Phorbols; Tetradecanoylphorbol Acetate

1982
Enhancement of altered-cell foci in baby mouse skin cultures by antitubulin treatment: nuclear mechanisms.
    Journal of cellular physiology, 1982, Volume: 113, Issue:2

    Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Colchicine; Cytochalasin D; Cytochalasins; Demecolcine; DNA; Light; Mice; Oxygen; Polyploidy; Skin; Tetradecanoylphorbol Acetate

1982
Surface antigens of melanocytes and melanomas. Markers of melanocyte differentiation and melanoma subsets.
    The Journal of experimental medicine, 1982, Dec-01, Volume: 156, Issue:6

    Topics: Adult; Animals; Antibodies, Monoclonal; Antigens, Neoplasm; Antigens, Surface; Cell Differentiation; Cell Transformation, Neoplastic; Cholera Toxin; Female; Humans; Infant, Newborn; Melanoma; Mice; Pregnancy; Skin; Tetradecanoylphorbol Acetate

1982
Tumor promoter induces loss of anchorage dependence in human skin fibroblasts from individuals genetically predisposed to cancer.
    Experimental cell biology, 1980, Volume: 48, Issue:3

    Topics: Adenoma; Agar; Animals; Cell Transformation, Neoplastic; Cells, Cultured; Colonic Neoplasms; Fibroblasts; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Phorbols; Rectal Neoplasms; Skin; Tetradecanoylphorbol Acetate

1980
Effect of 12-O-tetradecanoylphorbol-13-acetate on two charateristics of transformation acquired sequentially by ENU-exposed rat brain cells.
    British journal of cancer, 1980, Volume: 42, Issue:5

    Topics: Agar; Animals; Brain; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Ethylnitrosourea; Phorbols; Plasminogen Activators; Rats; Tetradecanoylphorbol Acetate

1980
Cell culture tumor promotion experiments with saccharin, phorbol myristate acetate and several common food materials.
    Cancer letters, 1980, Volume: 10, Issue:1

    Topics: Animals; Ascorbic Acid; Cell Transformation, Neoplastic; Cells, Cultured; Mice; Pantothenic Acid; Phorbols; Saccharin; Tetradecanoylphorbol Acetate; Tryptophan

1980
Effects of tumor promoters and extracellular calcium on the growth of normal, transformed and temperature sensitive rat liver epithelial cells.
    Cancer letters, 1980, Volume: 10, Issue:1

    Topics: Animals; Calcium; Cell Line; Cell Transformation, Neoplastic; Epithelium; Liver; Mutation; Phorbols; Rats; Temperature; Tetradecanoylphorbol Acetate

1980
Chemical carcinogenesis studies in mouse epidermal cell cultures.
    Current problems in dermatology, 1980, Volume: 10

    Topics: Animals; Carcinogens; Cell Differentiation; Cell Transformation, Neoplastic; Cells, Cultured; Environmental Exposure; Enzyme Induction; Epidermal Cells; Epidermis; Methylnitronitrosoguanidine; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin

1980
Enhancement of carcinogenesis in cultured respiratory tract epithelium by 12-0-tetradecanoylphorbol-13-acetate.
    International journal of cancer, 1980, Sep-15, Volume: 26, Issue:3

    Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Epithelium; Female; Methylnitronitrosoguanidine; Neoplasms, Experimental; Phorbols; Rats; Tetradecanoylphorbol Acetate; Time Factors; Trachea; Tracheal Neoplasms

1980
Initiation of C3H/10T1/2 cell transformation by formaldehyde.
    Cancer letters, 1981, Volume: 13, Issue:4

    Topics: Animals; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Drug Interactions; Formaldehyde; Formates; Methanol; Mice; Phorbols; Tetradecanoylphorbol Acetate

1981
Initiator and promoter induced specific changes in epidermal function and biological potential.
    Journal of supramolecular structure and cellular biochemistry, 1981, Volume: 17, Issue:3

    Topics: Animals; Animals, Newborn; Calcium; Cell Differentiation; Cell Transformation, Neoplastic; Cells, Cultured; Enzyme Induction; Kinetics; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Ornithine Decarboxylase; Phorbols; Skin; Skin Physiological Phenomena; Tetradecanoylphorbol Acetate

1981
Chemical transformation of cultured skin fibroblasts from humans genetically predisposed to cancer.
    Cancer detection and prevention, 1981, Volume: 4, Issue:1-4

    Topics: Cell Transformation, Neoplastic; Cells, Cultured; Fibroblasts; Gardner Syndrome; Humans; Methylnitronitrosoguanidine; Skin; Tetradecanoylphorbol Acetate

1981
An in vitro model of pancreas carcinogenesis: two-stage MNU--TPA effect.
    The American journal of pathology, 1980, Volume: 98, Issue:3

    Topics: Animals; Cell Transformation, Neoplastic; Hyperplasia; Methylnitrosourea; Mice; Mice, Nude; Models, Biological; Necrosis; Neoplasm Transplantation; Nitrosourea Compounds; Organ Culture Techniques; Pancreas; Pancreatic Neoplasms; Phorbols; Rats; Tetradecanoylphorbol Acetate; Transplantation, Heterologous

1980
Effect of time and duration of exposure to 12-O-tetradecanoylphorbol-13-acetate on x-ray transformation of C3H 10T 1/2 cells.
    Cancer research, 1980, Volume: 40, Issue:6

    Topics: Animals; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Cocarcinogenesis; Mice; Phorbols; Tetradecanoylphorbol Acetate; Time Factors; X-Rays

1980
Regulation of polyamine biosynthesis in normal and transformed hamster cells in culture.
    Biochimica et biophysica acta, 1980, Oct-01, Volume: 632, Issue:2

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Cricetinae; Enzyme Induction; Fibroblasts; Ornithine Decarboxylase; Phorbols; Polyamines; Putrescine; Spermidine; Spermine; Tetradecanoylphorbol Acetate

1980
Induction of tumor cytostatic macrophages by 12-0-tetradecanoyl phorbol-13-acetate (TPA).
    Clinical immunology and immunopathology, 1980, Volume: 17, Issue:4

    Topics: Animals; Cell Transformation, Neoplastic; Cytoplasmic Granules; Growth Inhibitors; Hexosephosphates; Lymphoma; Macrophages; Mice; Mice, Inbred C57BL; Pinocytosis; Tetradecanoylphorbol Acetate; Thymidine; Time Factors

1980
Modification of sister chromatid exchanges and radiation-induced transformation in rodent cells by the tumor promoter 12-O-tetradecanoylphorbol-13-acetate and two retinoids.
    Cancer research, 1981, Volume: 41, Issue:2

    Topics: Animals; Cell Division; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; Cocarcinogenesis; Cricetinae; Crossing Over, Genetic; Mice; Phorbols; Sister Chromatid Exchange; Tetradecanoylphorbol Acetate; Tretinoin

1981
Demonstration by DNA fingerprint analysis of genomic instability in mouse BALB 3T3 cells during cell transformation.
    Mutation research, 1994, Jan-16, Volume: 304, Issue:2

    Topics: 3T3 Cells; Animals; Base Sequence; Cell Line, Transformed; Cell Transformation, Neoplastic; Cloning, Molecular; DNA Damage; DNA Fingerprinting; DNA Probes; DNA, Satellite; Methylcholanthrene; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Mutagenesis; Mutagens; Tetradecanoylphorbol Acetate; Ultraviolet Rays

1994
12-O-tetradecanoylphorbol-13-acetate promotion of transgenic mice expressing epidermal-targeted v-fos induces rasHA-activated papillomas and carcinomas without p53 mutation: association of v-fos expression with promotion and tumor autonomy.
    Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1995, Volume: 6, Issue:5

    Topics: Animals; Base Sequence; Biomarkers; Carcinoma; Cell Differentiation; Cell Transformation, Neoplastic; DNA, Neoplasm; Epidermis; Gene Expression Regulation, Neoplastic; Genes, fos; Genes, p53; Genes, ras; Hyperplasia; Keratins; Keratosis; Mice; Mice, Transgenic; Molecular Sequence Data; Mutation; Oncogene Proteins v-fos; Papilloma; ras Proteins; RNA, Neoplasm; Tetradecanoylphorbol Acetate

1995
Effects of curcumin, demethoxycurcumin, bisdemethoxycurcumin and tetrahydrocurcumin on 12-O-tetradecanoylphorbol-13-acetate-induced tumor promotion.
    Carcinogenesis, 1995, Volume: 16, Issue:10

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Cell Line; Cell Transformation, Neoplastic; Coumaric Acids; Curcumin; Diarylheptanoids; Dose-Response Relationship, Drug; Enzyme Induction; Female; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; Skin; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Time Factors

1995
Genetic alterations cooperate with v-Ha-ras to accelerate multistage carcinogenesis in TG.AC transgenic mouse skin.
    Cancer research, 1995, Jul-15, Volume: 55, Issue:14

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Base Composition; Base Sequence; Carcinoma, Squamous Cell; Cell Division; Cell Transformation, Neoplastic; Cocarcinogenesis; Diglycerides; Female; Fibrosarcoma; Genes, p53; Genes, ras; Mice; Mice, Transgenic; Molecular Sequence Data; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate

1995
Benzoyl peroxide acts as a promoter of radiation induced malignant transformation in vitro.
    Biochemical and biophysical research communications, 1995, Jul-06, Volume: 212, Issue:1

    Topics: Animals; Ascorbic Acid; Benzoyl Peroxide; Cell Line; Cell Transformation, Neoplastic; Dose-Response Relationship, Radiation; Free Radicals; Hydroxyl Radical; Hydroxylation; Iron; Kinetics; Mice; Radiation-Sensitizing Agents; Tetradecanoylphorbol Acetate; X-Rays

1995
Improvement in the efficiency of the in vitro transformation assay method using BALB/3T3 A31-1-1 cells.
    Carcinogenesis, 1995, Volume: 16, Issue:8

    Topics: 3T3 Cells; Animals; Cell Transformation, Neoplastic; Culture Media; Dimethylnitrosamine; Methylnitronitrosoguanidine; Mice; Tetradecanoylphorbol Acetate

1995
Effects of the 6 beta-7 beta-epoxide of 12-O-tetradecanoyl-phorbol-13-acetate on radiation transformation in vitro.
    Cancer letters, 1995, Aug-16, Volume: 95, Issue:1-2

    Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Croton Oil; Epoxy Compounds; In Vitro Techniques; Mice; Tetradecanoylphorbol Acetate

1995
v-erbA cooperates with bFGF in neuroretina cell transformation.
    Virology, 1993, Volume: 192, Issue:2

    Topics: Animals; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Chick Embryo; Cloning, Molecular; Fibroblast Growth Factor 2; Genes, fos; Genes, gag; Genes, jun; Genes, ras; Insulin; Oncogene Proteins v-erbA; Oncogene Proteins v-raf; Oncogene Proteins, Viral; Oncogenes; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ets; Proto-Oncogenes; Proviruses; Receptor, ErbB-2; Retinal Ganglion Cells; Retroviridae Proteins, Oncogenic; RNA; Tetradecanoylphorbol Acetate; Transcription Factors

1993
Elevated expression of protein tyrosine kinase c-Yes, but not c-Src, in human malignant melanoma.
    Oncogene, 1993, Volume: 8, Issue:10

    Topics: Blotting, Western; Cell Transformation, Neoplastic; DNA Mutational Analysis; Humans; Melanocytes; Melanoma; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-yes; Proto-Oncogene Proteins pp60(c-src); Proto-Oncogenes; RNA, Messenger; src-Family Kinases; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1993
Initiating activity of quinones in the two-stage transformation of BALB/3T3 cells.
    Carcinogenesis, 1995, Volume: 16, Issue:3

    Topics: 3T3 Cells; Animals; Carcinogens; Cell Survival; Cell Transformation, Neoplastic; Mice; Mice, Inbred BALB C; Quinones; Tetradecanoylphorbol Acetate

1995
Induction of pseudofoci and inhibition of density-mediated neoplastic transformation by PMA in NIH 3T3 cells after short-term exposures.
    In vitro cellular & developmental biology. Animal, 1995, Volume: 31, Issue:3

    Topics: 3T3 Cells; Animals; Cell Aggregation; Cell Count; Cell Division; Cell Transformation, Neoplastic; DNA; Mice; Phorbol Esters; Tetradecanoylphorbol Acetate

1995
c-jun and multistage carcinogenesis: association of overexpression of introduced c-jun with progression toward a neoplastic endpoint in mouse JB6 cells sensitive to tumor promoter-induced transformation.
    Molecular carcinogenesis, 1995, Volume: 13, Issue:1

    Topics: Animals; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Gene Expression; Genes, jun; Humans; Mice; Phenotype; Proto-Oncogene Proteins c-jun; RNA, Messenger; Sensitivity and Specificity; Skin; Skin Neoplasms; Skin Physiological Phenomena; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transfection

1995
Expression of antisense osteopontin RNA inhibits tumor promoter-induced neoplastic transformation of mouse JB6 epidermal cells.
    Oncogene, 1995, Jun-01, Volume: 10, Issue:11

    Topics: Animals; Carcinogens; Cell Line, Transformed; Cell Transformation, Neoplastic; Dexamethasone; DNA, Complementary; Mammary Tumor Virus, Mouse; Mice; Mice, Inbred BALB C; Osteopontin; Phosphoproteins; RNA, Antisense; Sialoglycoproteins; Tetradecanoylphorbol Acetate

1995
Effects of okadaic acid on calcitriol- and phorbol ester-induced expression and phosphorylation of osteopontin in mouse JB6 epidermal cells.
    Annals of the New York Academy of Sciences, 1995, Apr-21, Volume: 760

    Topics: Animals; Calcitriol; Cell Adhesion; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Ethers, Cyclic; Gene Expression; In Vitro Techniques; Mice; Okadaic Acid; Osteopontin; Phosphoproteins; Phosphorylation; RNA, Messenger; Sialoglycoproteins; Tetradecanoylphorbol Acetate

1995
Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase gene expression in FRTL-5 cells. II. Down-regulation by v-K-ras oncogene.
    The Journal of biological chemistry, 1995, Jun-23, Volume: 270, Issue:25

    Topics: Acetates; Activating Transcription Factor 2; Animals; Antibodies; Cell Line; Cell Line, Transformed; Cell Transformation, Neoplastic; Colforsin; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Gene Expression Regulation, Enzymologic; Genes, ras; Hydroxymethylglutaryl CoA Reductases; Kinetics; Kirsten murine sarcoma virus; Leucine Zippers; Moloney murine sarcoma virus; Mutagenesis; Protein Kinase C; Rats; RNA, Messenger; Temperature; Tetradecanoylphorbol Acetate; Thyroid Gland; Transcription Factors

1995
[The role of TNF-alpha in the growth and differentiation of U937 cells induced by PMA and IFN-gamma].
    Shi yan sheng wu xue bao, 1994, Volume: 27, Issue:3

    Topics: Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Humans; Interferon-gamma; Leukemia, Monocytic, Acute; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

1994
Differential expression of prostaglandin H synthase isozymes during multistage carcinogenesis in mouse epidermis.
    Molecular carcinogenesis, 1995, Volume: 12, Issue:1

    Topics: Amino Acid Sequence; Animals; Carcinoma; Cell Transformation, Neoplastic; Cocarcinogenesis; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Isoenzymes; Keratinocytes; Mice; Molecular Sequence Data; Papilloma; Prostaglandin-Endoperoxide Synthases; Skin Neoplasms; Tetradecanoylphorbol Acetate

1995
Differential susceptibility of morphologically TPA-resistant and -sensitive Balb/c 3T3 variants to TPA-induced cell transformation: relationship to induction of membrane ruffling.
    Cell structure and function, 1994, Volume: 19, Issue:4

    Topics: 3T3 Cells; Actins; Animals; Cell Membrane; Cell Transformation, Neoplastic; Contact Inhibition; DNA Replication; Mice; Phosphorylation; Platelet-Derived Growth Factor; Protein Kinase C; Tetradecanoylphorbol Acetate

1994
Synergistic effects of chlordane and TPA in multistage morphological transformation of SHE cells.
    Carcinogenesis, 1995, Volume: 16, Issue:2

    Topics: Animals; Autoradiography; Carcinogens; Cell Communication; Cell Transformation, Neoplastic; Cells, Cultured; Chlordan; Cricetinae; DNA Adducts; Drug Synergism; Embryo, Mammalian; Mesocricetus; Phosphorus Radioisotopes; Tetradecanoylphorbol Acetate

1995
Effects of retinoids, beta-carotene, and canthaxanthin on UV- and X-ray-induced transformation of C3H10T1/2 cells in vitro.
    Nutrition and cancer, 1994, Volume: 22, Issue:3

    Topics: Animals; Antineoplastic Agents; beta Carotene; Canthaxanthin; Carotenoids; Cell Transformation, Neoplastic; Cells, Cultured; Mice; Mice, Inbred C3H; Retinoids; Tetradecanoylphorbol Acetate; Time Factors; Ultraviolet Rays; X-Rays

1994
Modulation of phorbol ester-induced HL-60 differentiation by prostaglandin E2.
    Mutation research, 1995, Volume: 328, Issue:1

    Topics: Carcinogenicity Tests; Carcinogens; Cell Differentiation; Cell Separation; Cell Transformation, Neoplastic; Dinoprostone; Dose-Response Relationship, Drug; Drug Synergism; Fibroblasts; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Leukemia; Phagocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1995
Transformation-sensitive cells in G2/M-phase are not promoted by TPA following 137Cs gamma-rays.
    International journal of radiation biology, 1993, Volume: 64, Issue:6

    Topics: Animals; Cell Transformation, Neoplastic; Cesium Radioisotopes; G2 Phase; Mice; Mice, Inbred C3H; Mitosis; Tetradecanoylphorbol Acetate

1993
Preferential primary-response gene expression in promotion-resistant versus promotion-sensitive JB6 cells.
    Molecular carcinogenesis, 1994, Volume: 11, Issue:2

    Topics: 3T3 Cells; Animals; Carcinogens; Cell Transformation, Neoplastic; DNA-Binding Proteins; Epidermal Growth Factor; Gene Expression; Genes; Immediate-Early Proteins; Mice; Mice, Inbred BALB C; Multigene Family; Proteins; Tetradecanoylphorbol Acetate; Tristetraprolin

1994
Expression and function of connexin in normal and transformed human keratinocytes in culture.
    Carcinogenesis, 1994, Volume: 15, Issue:9

    Topics: Carcinoma, Squamous Cell; Cell Communication; Cell Line, Transformed; Cell Transformation, Neoplastic; Cells, Cultured; Connexins; Gap Junctions; Humans; Keratinocytes; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transfection

1994
Proliferative responses of epithelial cells to 8-bromo-cyclic AMP and to a phorbol ester change during breast pathogenesis.
    Journal of cellular physiology, 1994, Volume: 161, Issue:1

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Biopsy; Breast; Breast Neoplasms; Cell Division; Cell Line; Cell Line, Transformed; Cell Transformation, Neoplastic; Cholera Toxin; Epithelium; Humans; Reference Values; Tetradecanoylphorbol Acetate; Time Factors

1994
Modification of invasion and differentiation in human melanoma cell clones.
    Melanoma research, 1994, Volume: 4, Issue:4

    Topics: Cell Survival; Cell Transformation, Neoplastic; Chemotaxis; Doxorubicin; Humans; Melanoma; Neoplasm Invasiveness; Plasminogen Activators; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured

1994
Effect of curcumin on 12-O-tetradecanoylphorbol-13-acetate- and ultraviolet B light-induced expression of c-Jun and c-Fos in JB6 cells and in mouse epidermis.
    Carcinogenesis, 1994, Volume: 15, Issue:10

    Topics: Animals; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Cocarcinogenesis; Curcumin; Drug Interactions; Female; Gene Expression Regulation; Hyperplasia; Mice; Mice, Hairless; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Ultraviolet Rays

1994
Enhanced tumorigenesis by small, protracted doses of densely ionizing radiation.
    Chinese medical journal, 1994, Volume: 107, Issue:6

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Dose-Response Relationship, Radiation; G2 Phase; Mice; Mice, Inbred C3H; Neoplasms, Radiation-Induced; Radiation Dosage; Radiation, Ionizing; Radon; Tetradecanoylphorbol Acetate; Time Factors

1994
[Inhibitory effect of a third generation retinoid R8923 and all-trans retinoic acid on two-stage chemical carcinogenesis of BALB/3T3-A31 cells in vitro].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 1994, Volume: 16, Issue:3

    Topics: 3T3 Cells; Animals; Antineoplastic Agents; Cell Transformation, Neoplastic; Methylcholanthrene; Mice; Mice, Inbred BALB C; Retinoids; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured

1994
Deficiency of tyrosine phosphorylation in a Balb/c 3T3 cell variant hypersensitive to phorbol ester-induced cell transformation.
    Carcinogenesis, 1994, Volume: 15, Issue:6

    Topics: 3T3 Cells; Animals; Cell Transformation, Neoplastic; Methylcholanthrene; Mice; Mice, Inbred BALB C; Phosphorylation; Tetradecanoylphorbol Acetate; Tyrosine

1994
Human GMP synthetase. Protein purification, cloning, and functional expression of cDNA.
    The Journal of biological chemistry, 1994, Sep-23, Volume: 269, Issue:38

    Topics: Amino Acid Sequence; Base Sequence; Carbon-Nitrogen Ligases; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cloning, Molecular; DNA Primers; DNA, Complementary; Gene Expression; Genetic Complementation Test; Humans; Ligases; Molecular Sequence Data; RNA, Messenger; Sequence Alignment; Sequence Homology, Amino Acid; Tetradecanoylphorbol Acetate

1994
Malignant transformation of human bronchial epithelial cells by radon-simulated alpha-particles.
    Carcinogenesis, 1994, Volume: 15, Issue:3

    Topics: Animals; Base Sequence; Bronchi; Cell Line, Transformed; Cell Transformation, Neoplastic; Genes, ras; Humans; Mice; Mice, Nude; Molecular Sequence Data; Mutation; Polymerase Chain Reaction; Radiation Dosage; Radon Daughters; Tetradecanoylphorbol Acetate

1994
Selective nature of phorbol 12-myristate 13-acetate-induced neoplastic transformation in NIH 3T3 cells.
    Proceedings of the National Academy of Sciences of the United States of America, 1994, Mar-15, Volume: 91, Issue:6

    Topics: 3T3 Cells; Animals; Cell Division; Cell Transformation, Neoplastic; Culture Media; Mice; Phenotype; Tetradecanoylphorbol Acetate

1994
Differential transformation efficiency but not AP-1 induction under anchorage-dependent and -independent conditions.
    Carcinogenesis, 1994, Volume: 15, Issue:5

    Topics: Animals; Cell Adhesion; Cell Transformation, Neoplastic; Cells, Cultured; Culture Media; DNA-Binding Proteins; Homeodomain Proteins; Mice; Minor Histocompatibility Antigens; Models, Biological; Proto-Oncogene Proteins c-bcl-2; Replication Protein C; Repressor Proteins; Saccharomyces cerevisiae Proteins; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate

1994
Inversion of carcinogen-promoter sequence: effects on mouse skin tumorigenesis and cellular growth kinetics.
    Indian journal of experimental biology, 1993, Volume: 31, Issue:8

    Topics: Animals; Cell Division; Cell Transformation, Neoplastic; Disease Models, Animal; Female; Humans; Hyperplasia; Methylcholanthrene; Mice; Mice, Inbred Strains; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate

1993
A functional Ets DNA-binding domain is required to maintain multipotency of hematopoietic progenitors transformed by Myb-Ets.
    Genes & development, 1994, Volume: 8, Issue:1

    Topics: Binding Sites; Cell Differentiation; Cell Transformation, Neoplastic; DNA; Gene Expression Regulation; Hematopoietic Stem Cells; Leukemia, Myelomonocytic, Acute; Mutation; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myb; Recombinant Fusion Proteins; Retroviridae Proteins, Oncogenic; Temperature; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1994
Blocking of tumor promoter-induced AP-1 activity inhibits induced transformation in JB6 mouse epidermal cells.
    Proceedings of the National Academy of Sciences of the United States of America, 1994, Jan-18, Volume: 91, Issue:2

    Topics: Animals; Base Sequence; Binding Sites; Cell Line; Cell Transformation, Neoplastic; DNA; Epidermal Growth Factor; Fluocinolone Acetonide; Gene Expression; Genes, fos; Genes, jun; Genes, Reporter; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Point Mutation; Proto-Oncogene Proteins c-jun; Skin; Tetradecanoylphorbol Acetate; Transfection; Tretinoin

1994
c-Myb prevents TPA-induced differentiation and cell death in v-Myb transformed monoblasts.
    Oncogene, 1994, Volume: 9, Issue:1

    Topics: Animals; Cell Cycle; Cell Death; Cell Differentiation; Cell Transformation, Neoplastic; Chickens; Oncogenes; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myb; Proto-Oncogenes; Tetradecanoylphorbol Acetate

1994
Sphingolipids inhibit multistage carcinogenesis and protein kinase C.
    Basic life sciences, 1993, Volume: 61

    Topics: Animals; Anticarcinogenic Agents; Carcinogenicity Tests; Cell Line; Cell Transformation, Neoplastic; Gamma Rays; Mice; Mice, Inbred C3H; Protein Kinase C; Sphingolipids; Sphingosine; Tetradecanoylphorbol Acetate

1993
Growth inhibition of human melanoma-derived cells by 12-O-tetradecanoyl phorbol 13-acetate.
    International journal of cancer, 1994, Jan-15, Volume: 56, Issue:2

    Topics: Cell Division; Cell Transformation, Neoplastic; Down-Regulation; Humans; Isoenzymes; Melanoma; Protein Kinase C; Sensitivity and Specificity; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1994
Protein kinase C alpha activates RAF-1 by direct phosphorylation.
    Nature, 1993, Jul-15, Volume: 364, Issue:6434

    Topics: 3T3 Cells; Amino Acid Sequence; Animals; Cell Line; Cell Transformation, Neoplastic; Cloning, Molecular; Enzyme Activation; Escherichia coli; Mice; Molecular Sequence Data; Moths; Mutation; Peptides; Protein Kinase C; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Rats; Recombinant Proteins; Serine; Tetradecanoylphorbol Acetate

1993
The epsilon isoform of protein kinase C is an oncogene when overexpressed in rat fibroblasts.
    Oncogene, 1993, Volume: 8, Issue:8

    Topics: Animals; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Down-Regulation; Fibroblasts; Isoenzymes; Oncogenes; Phenotype; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate

1993
Differential signal requirement for upregulation of HLA-class II molecules in human lymphoma B cells.
    Hematologic pathology, 1993, Volume: 7, Issue:2

    Topics: Antibodies; Calcimycin; Cell Transformation, Neoplastic; Gene Expression Regulation, Neoplastic; Histocompatibility Antigens Class II; Humans; Immunoglobulin M; Interleukin-4; Lymphoma, B-Cell; Protein Kinase C; Receptors, Fc; Receptors, IgE; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Up-Regulation

1993
Antipromoting effects of 5-lipoxygenase inhibitors, 3-nitro-2,4,6- trihydroxybenzamide derivatives, on TPA-promoted transformation in BALB 3T3 cells.
    Cancer letters, 1993, Jul-30, Volume: 71, Issue:1-3

    Topics: 3T3 Cells; Animals; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Hydroxamic Acids; Lipoxygenase Inhibitors; Methylcholanthrene; Mice; Tetradecanoylphorbol Acetate

1993
Interaction of HPV-18 and nitrosomethylurea in the induction of squamous cell carcinoma.
    Carcinogenesis, 1993, Volume: 14, Issue:2

    Topics: Animals; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cocarcinogenesis; DNA, Viral; Humans; Keratinocytes; Methylnitrosourea; Mice; Mice, Inbred BALB C; Mice, Nude; Papillomaviridae; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1993
Effect of glucocorticoids on TPA-induced inhibition of gap-junctional communication and morphological transformation in Syrian hamster embryo cells.
    Cancer letters, 1993, Aug-16, Volume: 72, Issue:1-2

    Topics: Animals; Cell Communication; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Embryo, Mammalian; Gap Junctions; Glucocorticoids; Tetradecanoylphorbol Acetate

1993
Immortalization of Syrian hamster embryo cells: probabilistic event or deterministic process.
    Cancer research, 1993, Oct-15, Volume: 53, Issue:20

    Topics: Animals; Benzo(a)pyrene; Cell Count; Cell Cycle; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Cellular Senescence; Cricetinae; Culture Techniques; Embryo, Mammalian; Kinetics; Mesocricetus; Models, Biological; Tetradecanoylphorbol Acetate; Time Factors

1993
Conditional transformation of cells and rapid activation of the mitogen-activated protein kinase cascade by an estradiol-dependent human raf-1 protein kinase.
    Molecular and cellular biology, 1993, Volume: 13, Issue:10

    Topics: 3T3 Cells; Animals; Base Sequence; Cell Transformation, Neoplastic; Cloning, Molecular; DNA; Enzyme Activation; Estradiol; Ethers, Cyclic; Humans; Kinetics; Mice; Mitogen-Activated Protein Kinase 1; Molecular Sequence Data; Okadaic Acid; Phosphorylation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Rats; Receptors, Estrogen; Retroviridae; Signal Transduction; Tetradecanoylphorbol Acetate

1993
Raf revertant cells resist transformation by non-nuclear oncogenes and are deficient in the induction of early response genes by TPA and serum.
    Oncogene, 1993, Volume: 8, Issue:2

    Topics: 3T3 Cells; Animals; Blood Physiological Phenomena; Cell Transformation, Neoplastic; Gene Expression; Genes, fos; Mice; Oncogene Proteins v-raf; Oncogenes; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-fos; Retroviridae Proteins, Oncogenic; Tetradecanoylphorbol Acetate

1993
Two phorbol ester receptor affinities in partially transformed human urothelial cells and decrease of receptor binding in desensitized cells.
    Experientia, 1993, Jan-15, Volume: 49, Issue:1

    Topics: Caenorhabditis elegans Proteins; Carrier Proteins; Cell Line, Transformed; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Humans; Phorbol 12,13-Dibutyrate; Protein Kinase C; Receptors, Drug; Tetradecanoylphorbol Acetate; Urinary Bladder; Urinary Bladder Neoplasms

1993
Intercellular communication in colonies of Syrian hamster embryo cells and the susceptibility for morphological transformation.
    Carcinogenesis, 1993, Volume: 14, Issue:2

    Topics: Animals; Cell Communication; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Dieldrin; Diethylhexyl Phthalate; Down-Regulation; Embryo, Mammalian; Intercellular Junctions; Mesocricetus; Tetradecanoylphorbol Acetate; Vanadates

1993
Differentiation-stage specific self-peptides bound by major histocompatibility complex class I molecules.
    The Journal of experimental medicine, 1993, Mar-01, Volume: 177, Issue:3

    Topics: Amino Acid Sequence; Cell Differentiation; Cell Transformation, Neoplastic; Chromatography, High Pressure Liquid; Flow Cytometry; Fluorescent Antibody Technique; Histocompatibility Antigens Class I; Humans; Leukemia, Myeloid; Major Histocompatibility Complex; Molecular Sequence Data; Peptides; Phenotype; Precipitin Tests; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1993
An immediate early human gene encodes an Id-like helix-loop-helix protein and is regulated by protein kinase C activation in diverse cell types.
    Oncogene, 1993, Volume: 8, Issue:3

    Topics: 3T3 Cells; Amino Acid Sequence; Animals; Base Sequence; Cell Transformation, Neoplastic; DNA-Binding Proteins; Enzyme Activation; Gene Expression Regulation; Genome, Human; Humans; Immunoglobulin Idiotypes; Inhibitor of Differentiation Proteins; Mice; Molecular Sequence Data; Protein Kinase C; Proteins; Sequence Homology, Amino Acid; Tetradecanoylphorbol Acetate; Transcription Factors

1993
Severely decreased MARCKS expression correlates with ras reversion but not with mitogenic responsiveness.
    Oncogene, 1993, Volume: 8, Issue:3

    Topics: 3T3 Cells; Animals; Cell Transformation, Neoplastic; Cells, Cultured; DNA; Genes, ras; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Mice; Myristoylated Alanine-Rich C Kinase Substrate; Phenotype; Phosphorylation; Protein Kinase C; Proteins; Tetradecanoylphorbol Acetate; Transfection

1993
Overexpression of protein kinase C-delta and -epsilon in NIH 3T3 cells induces opposite effects on growth, morphology, anchorage dependence, and tumorigenicity.
    The Journal of biological chemistry, 1993, Mar-25, Volume: 268, Issue:9

    Topics: 3T3 Cells; Animals; Biological Transport; Blotting, Northern; Blotting, Western; Brain; Cell Adhesion; Cell Division; Cell Transformation, Neoplastic; Cloning, Molecular; Enzyme Activation; Enzyme Stability; Indoles; Isoenzymes; Kinetics; Maleimides; Mice; Mice, Inbred C57BL; Mice, Nude; Neoplasms, Experimental; Protein Kinase C; Tetradecanoylphorbol Acetate

1993
Suppression of oncogene-induced transformation by a deletion mutant of c-jun.
    Oncogene, 1993, Volume: 8, Issue:4

    Topics: Animals; Base Sequence; Binding, Competitive; Cell Transformation, Neoplastic; Cells, Cultured; DNA Mutational Analysis; DNA-Binding Proteins; Genes, Dominant; Genes, ras; Genes, Suppressor; Humans; In Vitro Techniques; Molecular Sequence Data; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats; Sequence Deletion; Tetradecanoylphorbol Acetate; Transcriptional Activation

1993
Differential effects of TPA and pristane on gene expression and transformation in mouse epidermal cells.
    Experimental cell research, 1993, Volume: 205, Issue:2

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Epidermal Cells; Gene Expression; In Vitro Techniques; Mice; Promoter Regions, Genetic; Regulatory Sequences, Nucleic Acid; Terpenes; Tetradecanoylphorbol Acetate; Transcription, Genetic

1993
1 alpha,25-Dihydroxyvitamin D3 enhances 12-O-tetradecanoylphorbol-13-acetate- induced tumorigenic transformation and osteopontin expression in mouse JB6 epidermal cells.
    Cancer research, 1993, May-15, Volume: 53, Issue:10 Suppl

    Topics: Animals; Calcitriol; Cell Adhesion; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Cocarcinogenesis; Drug Synergism; Gene Expression; Mice; Osteopontin; Phosphorylation; RNA, Messenger; Sialoglycoproteins; Skin; Skin Neoplasms; Skin Physiological Phenomena; Tetradecanoylphorbol Acetate

1993
Alterations in a voltage-gated K+ current during the differentiation of ML-1 human myeloblastic leukemia cells.
    The Journal of membrane biology, 1993, Volume: 132, Issue:3

    Topics: 4-Aminopyridine; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Humans; Ion Channel Gating; Leukemia, Myeloid, Acute; Membrane Potentials; Potassium Channels; Tetradecanoylphorbol Acetate; Tetraethylammonium Compounds; Tumor Cells, Cultured

1993
60 Hz magnetic field acts as co-promoter in focus formation of C3H/10T1/2 cells.
    Carcinogenesis, 1993, Volume: 14, Issue:5

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Fibroblasts; Magnetics; Mice; Mice, Inbred C3H; Tetradecanoylphorbol Acetate; Video Recording

1993
Regulation of Myc and Mad during epidermal differentiation and HPV-associated tumorigenesis.
    Oncogene, 1995, Dec-21, Volume: 11, Issue:12

    Topics: Animals; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Cell Differentiation; Cell Transformation, Neoplastic; Cells, Cultured; DNA-Binding Proteins; Humans; Keratinocytes; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Transgenic; Papillomaviridae; Proto-Oncogene Proteins c-myc; Repressor Proteins; Tetradecanoylphorbol Acetate

1995
A novel function of CD40: induction of cell death in transformed cells.
    The Journal of experimental medicine, 1996, Jan-01, Volume: 183, Issue:1

    Topics: Animals; Antibodies; Apoptosis; CD40 Antigens; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Dose-Response Relationship, Drug; Drug Synergism; Epithelial Cells; Epithelium; fas Receptor; Growth Inhibitors; Humans; Interleukin-1; Mesoderm; Mice; Receptors, Tumor Necrosis Factor; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

1996
Comparison of propylene oxide and epichlorohydrin effects in two transformation tests (C3H/10T1/2 and SHE cells).
    Toxicology letters, 1995, Nov-15, Volume: 81, Issue:2-3

    Topics: Animals; Carcinogens; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Epichlorohydrin; Epoxy Compounds; Female; Mice; Mice, Inbred C3H; Mutagenicity Tests; Pregnancy; Tetradecanoylphorbol Acetate

1995
Inhibition of tumor promoter-induced transformation by retinoids that transrepress AP-1 without transactivating retinoic acid response element.
    Cancer research, 1996, Feb-01, Volume: 56, Issue:3

    Topics: Animals; Anticarcinogenic Agents; Base Sequence; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Gene Expression; Genes, Reporter; Luciferases; Mice; Molecular Sequence Data; Promoter Regions, Genetic; Regulatory Sequences, Nucleic Acid; Retinoids; Sensitivity and Specificity; Skin; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcriptional Activation; Transfection; Tretinoin

1996
Sphingosine and its methylated derivative N,N-dimethylsphingosine (DMS) induce apoptosis in a variety of human cancer cell lines.
    International journal of cancer, 1996, May-03, Volume: 66, Issue:3

    Topics: Animals; Apoptosis; Cell Line; Cell Line, Transformed; Cell Transformation, Neoplastic; Cells, Cultured; Colonic Neoplasms; DNA, Neoplasm; Endothelium, Vascular; Flow Cytometry; Glomerular Mesangium; HL-60 Cells; Humans; Kinetics; Rats; Sphingosine; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Umbilical Veins

1996
Enhancement of BALB/c 3T3 cells transformation by 1,2-dibromoethane promoting effect.
    Carcinogenesis, 1996, Volume: 17, Issue:2

    Topics: 3T3 Cells; Animals; Carcinogens; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Ethane; Ethylene Dibromide; Hydrocarbons, Chlorinated; Methylnitronitrosoguanidine; Mice; Tetradecanoylphorbol Acetate

1996
Carcinogenesis in human skin grafted to SCID mice.
    Cancer research, 1996, Feb-15, Volume: 56, Issue:4

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Neoplasm; Carcinogens; Cell Differentiation; Cell Division; Cell Transformation, Neoplastic; Humans; Keratins; Ki-67 Antigen; Mice; Mice, SCID; Neoplasm Proteins; Nuclear Proteins; Papilloma; Skin Neoplasms; Skin Transplantation; Tetradecanoylphorbol Acetate; Transplantation, Heterologous; Ultraviolet Rays

1996
Overexpression of protein kinase C epsilon is oncogenic in rat colonic epithelial cells.
    Oncogene, 1996, Feb-15, Volume: 12, Issue:4

    Topics: Animals; Blotting, Western; Cell Adhesion; Cell Division; Cell Line; Cell Transformation, Neoplastic; Colon; Colonic Neoplasms; Epithelial Cells; Epithelium; Gene Expression; Genes, ras; Isoenzymes; Mice; Mice, Nude; Protein Kinase C; Rats; Recombinant Proteins; Tetradecanoylphorbol Acetate; Transfection; Transplantation, Heterologous

1996
Radiation-induced neoplastic transformation of stationary phase C3H/10T1/2 cells in response to different dose rates and to post-irradiation treatment with tumor promoter.
    Chemico-biological interactions, 1996, Volume: 101, Issue:1

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Embryo, Mammalian; Fibroblasts; Mice; Tetradecanoylphorbol Acetate

1996
Antioxidants inhibit the enhancement of malignant cell transformation induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin.
    Carcinogenesis, 1996, Volume: 17, Issue:6

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Anticarcinogenic Agents; Antioxidants; Ascorbic Acid; Carcinogens; Cell Transformation, Neoplastic; Drug Interactions; Enzyme Inhibitors; Fibroblasts; Isoquinolines; Mannitol; Methylnitronitrosoguanidine; Mice; Mice, Inbred C3H; Piperazines; Polychlorinated Dibenzodioxins; Protein Kinase C; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Vitamin E

1996
Drug-induced reversion of progression phenotype is accompanied by reversion of AP-1 phenotype in JB6 cells.
    In vitro cellular & developmental biology. Animal, 1996, Volume: 32, Issue:4

    Topics: 3T3 Cells; Animals; Cell Division; Cell Line; Cell Transformation, Neoplastic; Clone Cells; Colforsin; Epidermal Growth Factor; Fluocinolone Acetonide; Glucocorticoids; Mice; Phenotype; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transfection

1996
Studies on the mechanisms of tumorigenesis induced by polyetherurethanes in rats: leachable and biodegradable oligomers involving the diphenyl carbamate structure acted as an initiator on the transformation of Balb 3T3 cells.
    Journal of biomedical materials research, 1996, Volume: 31, Issue:3

    Topics: 3T3 Cells; Animals; Biocompatible Materials; Butylated Hydroxytoluene; Carbamates; Carcinogens; Cell Transformation, Neoplastic; Colony-Forming Units Assay; Methanol; Mice; Mice, Inbred BALB C; Polyurethanes; Tetradecanoylphorbol Acetate

1996
Chronic exposure of LLC-PK1 epithelia to the phorbol ester TPA produces polyp-like foci with leaky tight junctions and altered protein kinase C-alpha expression and localization.
    Experimental cell research, 1996, Aug-25, Volume: 227, Issue:1

    Topics: Animals; Carcinoma; Cell Membrane; Cell Membrane Permeability; Cell Transformation, Neoplastic; Clone Cells; Coloring Agents; Cytosol; Electric Impedance; Epithelial Cells; Epithelium; Isoenzymes; LLC-PK1 Cells; Mannitol; Protein Kinase C; Protein Kinase C-alpha; Ruthenium Red; Swine; Tetradecanoylphorbol Acetate; Tight Junctions

1996
Paradoxical tumor inhibitory effect of p53 loss in transgenic mice expressing epidermal-targeted v-rasHa, v-fos, or human transforming growth factor alpha.
    Cancer research, 1996, Oct-01, Volume: 56, Issue:19

    Topics: Animals; Animals, Newborn; Cell Differentiation; Cell Division; Cell Transformation, Neoplastic; Cocarcinogenesis; Crosses, Genetic; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Epidermis; Genes, fos; Genes, p53; Genes, ras; Hyperplasia; Keratinocytes; Mice; Mice, Knockout; Mice, Transgenic; Oncogene Protein p21(ras); Oncogene Proteins v-fos; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha; Transgenes

1996
pH effects on the lifespan and transformation frequency of Syrian hamster embryo (SHE) cells.
    Carcinogenesis, 1996, Volume: 17, Issue:9

    Topics: Animals; Benzo(a)pyrene; Carcinogens; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; Cellular Senescence; Cricetinae; Embryo, Mammalian; Hydrogen-Ion Concentration; Mesocricetus; Nickel; Tetradecanoylphorbol Acetate; Time Factors; X-Rays

1996
Protection against malignant conversion in SENCAR mouse skin by all trans retinoic acid: inhibition of the ras p21-processing enzyme farnesyltransferase and Ha-ras p21 membrane localization.
    Molecular carcinogenesis, 1996, Volume: 17, Issue:1

    Topics: Alkyl and Aryl Transferases; Animals; Carcinoma; Cell Compartmentation; Cell Membrane; Cell Transformation, Neoplastic; Cytosol; Diterpenes; Enzyme Inhibitors; Mice; Papilloma; Proto-Oncogene Proteins p21(ras); Skin; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate; Transferases; Tretinoin

1996
Up-regulation of vascular endothelial growth factor/vascular permeability factor in mouse skin carcinogenesis correlates with malignant progression state and activated H-ras expression levels.
    Cancer research, 1996, Dec-01, Volume: 56, Issue:23

    Topics: Animals; Carcinoma, Squamous Cell; Cell Line, Transformed; Cell Transformation, Neoplastic; Disease Progression; Endothelial Growth Factors; Female; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Genes, ras; Interleukin 1 Receptor Antagonist Protein; Keratinocytes; Lymphokines; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred SENCAR; Neoplasm Metastasis; Neoplasm Proteins; Neovascularization, Pathologic; Oncogene Protein p21(ras); Papilloma; Precancerous Conditions; Proto-Oncogene Proteins p21(ras); RNA, Messenger; RNA, Neoplasm; Sialoglycoproteins; Skin Neoplasms; Species Specificity; Tetradecanoylphorbol Acetate; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

1996
PKC epsilon functions as an oncogene by enhancing activation of the Raf kinase.
    Oncogene, 1996, Dec-19, Volume: 13, Issue:12

    Topics: Animals; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Colony-Forming Units Assay; Enzyme Activation; Fibroblasts; Genes, ras; Genetic Vectors; Isoenzymes; Oncogenes; Protein Kinase C; Protein Kinase C-epsilon; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Rats; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection

1996
Asbestos promotes morphological transformation and elevates expression of a gene family invariably induced by tumor promoters in C3H/10T1/2 cells.
    Carcinogenesis, 1996, Volume: 17, Issue:12

    Topics: Animals; Antioxidants; Asbestos; Asbestos, Crocidolite; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Gene Expression Regulation; Glycoproteins; Intercellular Signaling Peptides and Proteins; Mice; Mice, Inbred C3H; Prolactin; RNA, Messenger; Tetradecanoylphorbol Acetate

1996
Phosphatidylinositol-3 kinase is necessary for 12-O-tetradecanoylphorbol-13-acetate-induced cell transformation and activated protein 1 activation.
    The Journal of biological chemistry, 1997, Feb-14, Volume: 272, Issue:7

    Topics: Androstadienes; Animals; Cell Line; Cell Transformation, Neoplastic; Chromones; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Epidermal Cells; Epidermis; Insulin; Mice; Morpholines; Phosphatidylinositol 3-Kinases; Phosphotransferases (Alcohol Group Acceptor); Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Wortmannin

1997
Manganese superoxide dismutase expression inhibits soft agar growth in JB6 clone41 mouse epidermal cells.
    Carcinogenesis, 1997, Volume: 18, Issue:3

    Topics: Animals; Carcinogens; Cell Line, Transformed; Cell Transformation, Neoplastic; Disease Susceptibility; Enzyme Induction; Epidermal Cells; Gene Expression Regulation; Genes, fos; Genes, jun; Humans; Mice; Oxidative Stress; Recombinant Fusion Proteins; Signal Transduction; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transfection

1997
Inhibition of activator protein 1 activity and neoplastic transformation by aspirin.
    The Journal of biological chemistry, 1997, Apr-11, Volume: 272, Issue:15

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Aspirin; Calcium-Calmodulin-Dependent Protein Kinases; Carcinogens; Cell Adhesion; Cell Transformation, Neoplastic; Cyclooxygenase Inhibitors; Diethylstilbestrol; Genes, jun; Genes, ras; Hydrogen-Ion Concentration; Indomethacin; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphorylation; Sodium Salicylate; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Tumor Cells, Cultured

1997
Focus formation of C3H/10T1/2 cells and exposure to a 836.55 MHz modulated radiofrequency field.
    Bioelectromagnetics, 1997, Volume: 18, Issue:3

    Topics: Analysis of Variance; Animals; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Coculture Techniques; Dose-Response Relationship, Drug; Electromagnetic Fields; Fibroblasts; Mice; Mice, Inbred C3H; Microscopy, Video; Radio Waves; Tetradecanoylphorbol Acetate

1997
Differentiating agents modulate topoisomerase I activity in U-937 promonocytic cells.
    European journal of pharmacology, 1997, Apr-11, Volume: 324, Issue:1

    Topics: Acetamides; Antineoplastic Agents; Blotting, Northern; Blotting, Western; Carcinogens; Cell Transformation, Neoplastic; DNA Topoisomerases, Type I; Electrophoresis, Polyacrylamide Gel; Humans; Leukemia, Myeloid; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tretinoin; Tumor Cells, Cultured

1997
Tumor promotion by depleting cells of protein kinase C delta.
    Molecular and cellular biology, 1997, Volume: 17, Issue:6

    Topics: Animals; Antineoplastic Agents; Bryostatins; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Down-Regulation; Fibroblasts; Isoenzymes; Lactones; Macrolides; Phenotype; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-delta; Protein Kinase C-epsilon; Proto-Oncogene Proteins pp60(c-src); Rats; Tetradecanoylphorbol Acetate; Transfection

1997
Expression of an Epstein-Barr-virus receptor and Epstein-Barr-virus-dependent transformation of human nasopharyngeal epithelial cells.
    International journal of cancer, 1997, May-29, Volume: 71, Issue:5

    Topics: Base Sequence; Binding Sites; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; DNA; DNA, Viral; Embryo, Mammalian; Epithelium; Gene Expression; Herpesvirus 4, Human; Humans; Molecular Sequence Data; Nasopharyngeal Neoplasms; Nasopharynx; Polymerase Chain Reaction; Receptors, Complement 3d; Receptors, Virus; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1997
Grafting assay distinguishes promotion sensitive from promotion resistant JB6 cells.
    Carcinogenesis, 1997, Volume: 18, Issue:6

    Topics: Animals; Carcinogens; Cell Line, Transformed; Cell Transformation, Neoplastic; Disease Models, Animal; Fibroblasts; Male; Mice; Mice, Inbred BALB C; Mice, Inbred SENCAR; Mice, Nude; Mutation; Neoplasm Transplantation; Phenotype; Sensitivity and Specificity; Skin; Skin Neoplasms; Skin Physiological Phenomena; Tetradecanoylphorbol Acetate; Transcription Factor AP-1

1997
IkappaB alpha is a target for the mitogen-activated 90 kDa ribosomal S6 kinase.
    The EMBO journal, 1997, Jun-02, Volume: 16, Issue:11

    Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Transformation, Neoplastic; Cell Transformation, Viral; COS Cells; DNA-Binding Proteins; Humans; I-kappa B Proteins; Mitogens; Mutation; NF-kappa B; NF-kappa B p50 Subunit; NF-KappaB Inhibitor alpha; Phosphorylation; Precipitin Tests; Protein Binding; Protein Precursors; Protein Serine-Threonine Kinases; Ribosomal Protein S6 Kinases; Serine; Signal Transduction; Substrate Specificity; Tetradecanoylphorbol Acetate

1997
Inositol hexaphosphate inhibits cell transformation and activator protein 1 activation by targeting phosphatidylinositol-3' kinase.
    Cancer research, 1997, Jul-15, Volume: 57, Issue:14

    Topics: Animals; Anticarcinogenic Agents; Cell Line; Cell Transformation, Neoplastic; Epidermal Growth Factor; Mice; Phosphatidylinositol 3-Kinases; Phosphotransferases (Alcohol Group Acceptor); Phytic Acid; Tetradecanoylphorbol Acetate; Transcription Factor AP-1

1997
Power frequency magnetic fields do not contribute to transformation of JB6 cells.
    Carcinogenesis, 1997, Volume: 18, Issue:7

    Topics: Animals; Blood Physiological Phenomena; Cell Transformation, Neoplastic; Cells, Cultured; Dose-Response Relationship, Drug; Magnetics; Mice; Tetradecanoylphorbol Acetate

1997
A dominant negative mutant of jun blocking 12-O-tetradecanoylphorbol-13-acetate-induced invasion in mouse keratinocytes.
    Molecular carcinogenesis, 1997, Volume: 19, Issue:3

    Topics: Animals; Anticarcinogenic Agents; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Glycoproteins; Keratinocytes; Matrix Metalloproteinases, Membrane-Associated; Metalloendopeptidases; Mice; Mutation; NF-kappa B; Proto-Oncogene Proteins c-jun; RNA, Messenger; Tetradecanoylphorbol Acetate; Tissue Inhibitor of Metalloproteinases; Transcription Factor AP-1; Transcriptional Activation; Transfection; Tumor Suppressor Protein p53

1997
Inhibitory effects of shouseiryu-to on two-stage carcinogenesis. II. Anti-tumor-promoting activities of lignans from Asiasarum heterotropoides var. mandshuricum.
    Biological & pharmaceutical bulletin, 1997, Volume: 20, Issue:7

    Topics: Animals; Anticarcinogenic Agents; Antigens, Viral; Cell Line; Cell Transformation, Neoplastic; Dioxoles; Female; Furans; Lignans; Lung Neoplasms; Mice; Mice, Inbred ICR; Phenols; Skin Neoplasms; Tetradecanoylphorbol Acetate

1997
VEGF mRNA is stabilized by ras and tyrosine kinase oncogenes, as well as by UV radiation--evidence for divergent stabilization pathways.
    Growth factors (Chur, Switzerland), 1997, Volume: 14, Issue:2-3

    Topics: 3T3 Cells; Acetylcysteine; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Hypoxia; Cell Transformation, Neoplastic; DNA-Binding Proteins; Endothelial Growth Factors; Genes, ras; Genistein; Humans; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Isoflavones; Lymphokines; Mice; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Nuclear Proteins; Phosphorylation; Protein-Tyrosine Kinases; ras Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription Factors; Tumor Cells, Cultured; Ultraviolet Rays; Up-Regulation; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

1997
Inhibitors of both nuclear factor-kappaB and activator protein-1 activation block the neoplastic transformation response.
    Cancer research, 1997, Aug-15, Volume: 57, Issue:16

    Topics: Animals; Anticarcinogenic Agents; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; DNA; Genes, Reporter; Mice; NF-kappa B; Pyrrolidines; Retinoids; Tetradecanoylphorbol Acetate; Thiocarbamates; Time Factors; Transcription Factor AP-1; Transcriptional Activation; Transfection; Tumor Necrosis Factor-alpha

1997
Inhibitory effects of phytopolyphenols on TPA-induced transformation, PKC activation, and c-jun expression in mouse fibroblast cells.
    Nutrition and cancer, 1997, Volume: 28, Issue:2

    Topics: 3T3 Cells; Animals; Carcinogens; Catechin; Cell Line; Cell Transformation, Neoplastic; Curcumin; Down-Regulation; Fibroblasts; Flavonoids; Flavonols; Gene Expression Regulation, Neoplastic; Genes, jun; Mice; Phenols; Polymers; Protein Kinase C; Tetradecanoylphorbol Acetate

1997
Epstein-Barr virus in synergy with tumor-promoter-induced malignant transformation of immortalized human epithelial cells.
    Journal of cancer research and clinical oncology, 1997, Volume: 123, Issue:8

    Topics: Animals; Carcinogens; Cell Division; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Cocarcinogenesis; DNA, Viral; Epithelium; Female; Herpesvirus 4, Human; Humans; Kidney; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Receptors, Complement 3d; Receptors, Virus; Tetradecanoylphorbol Acetate

1997
Differential activation of keratinocyte phospholipase A2S by tumor promoters and other irritants.
    Advances in experimental medicine and biology, 1997, Volume: 407

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Cytosol; Eicosanoids; Enzyme Activation; Enzyme Inhibitors; Epidermal Cells; Fatty Acids; Isoenzymes; Keratinocytes; Membrane Lipids; Mice; Naphthalenes; Oligonucleotides, Antisense; Papilloma; Phosphatidylcholines; Phospholipases A; Phospholipids; Pyrones; Recombinant Fusion Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured

1997
Inhibition of tumor promoter-induced activator protein 1 activation and cell transformation by tea polyphenols, (-)-epigallocatechin gallate, and theaflavins.
    Cancer research, 1997, Oct-01, Volume: 57, Issue:19

    Topics: Animals; Anticarcinogenic Agents; Biflavonoids; Catechin; Cell Transformation, Neoplastic; Chemoprevention; Epidermal Growth Factor; Mice; Phosphorylation; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-jun; Signal Transduction; Tea; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcriptional Activation

1997
Relationship between exposure to TPA and appearance of transformed cells in MNNG-initiated transformation of BALB/c 3T3 cells.
    International journal of cancer, 1997, Oct-09, Volume: 73, Issue:2

    Topics: 3T3 Cells; Animals; Carcinogens; Cell Count; Cell Line, Transformed; Cell Transformation, Neoplastic; Methylnitronitrosoguanidine; Mice; Mice, Inbred BALB C; Tetradecanoylphorbol Acetate; Time Factors

1997
Calcitriol enhancement of TPA-induced tumorigenic transformation is mediated through vitamin D receptor-dependent and -independent pathways.
    Clinical & experimental metastasis, 1997, Volume: 15, Issue:6

    Topics: 25-Hydroxyvitamin D3 1-alpha-Hydroxylase; Animals; Calcitriol; Cell Division; Cell Line; Cell Transformation, Neoplastic; Epidermal Cells; Mice; Osteopontin; Receptors, Calcitriol; Sialoglycoproteins; Tetradecanoylphorbol Acetate; Transfection; Vitamin D

1997
bcl-2 enhancement of malignant transformation in mouse epidermal JB6 cells.
    Molecular carcinogenesis, 1997, Volume: 20, Issue:2

    Topics: Animals; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Clone Cells; Cocarcinogenesis; Gene Expression; Genes, fos; Genes, jun; Mice; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; RNA, Messenger; Skin; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcriptional Activation; Transfection

1997
Oncogenic transformation of Syrian hamster embryo cells by 5.3-MeV alpha particles and a tumor promoter phorbol ester.
    Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih, 1996, Volume: 11, Issue:4

    Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Embryo, Mammalian; Mesocricetus; Plutonium; Tetradecanoylphorbol Acetate

1996
Selenocompounds induce a redox modulation of protein kinase C in the cell, compartmentally independent from cytosolic glutathione: its role in inhibition of tumor promotion.
    Archives of biochemistry and biophysics, 1997, Dec-01, Volume: 348, Issue:1

    Topics: Animals; Anticarcinogenic Agents; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Chromatography, DEAE-Cellulose; Cystine; Cytosol; Glutathione; Glutathione Disulfide; Isoenzymes; Kinetics; Mice; Organoselenium Compounds; Oxidation-Reduction; Phorbol 12,13-Dibutyrate; Protein Kinase C; Sodium Selenite; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1997
Inhibition of tumor promoter activity toward mouse fibroblasts and their in vitro transformation by tissue inhibitor of metalloproteinases-1 (TIMP-1).
    Carcinogenesis, 1997, Volume: 18, Issue:11

    Topics: 3T3 Cells; Animals; Antineoplastic Agents; Cell Communication; Cell Transformation, Neoplastic; Fibroblasts; Gap Junctions; Metalloendopeptidases; Methylnitronitrosoguanidine; Mice; Protease Inhibitors; Tetradecanoylphorbol Acetate; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2

1997
Signal transduction in fibroblasts stably transformed by [Val12]Ras--the activities of extracellular-signal-regulated kinase and Jun N-terminal kinase are only moderately increased, and the activity of the delta-inhibitor of c-Jun is not alleviated.
    European journal of biochemistry, 1997, Nov-01, Volume: 249, Issue:3

    Topics: Animals; Benzodiazepines; Blotting, Northern; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line, Transformed; Cell Transformation, Neoplastic; Genes, ras; Histones; Humans; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases; Myelin Basic Protein; Proto-Oncogene Proteins c-jun; Rats; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factors; Transcriptional Activation; Tumor Cells, Cultured

1997
Shortage of mitogen-activated protein kinase is responsible for resistance to AP-1 transactivation and transformation in mouse JB6 cells.
    Proceedings of the National Academy of Sciences of the United States of America, 1998, Jan-06, Volume: 95, Issue:1

    Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Epidermal Growth Factor; Epidermis; Mice; Phosphorylation; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcriptional Activation

1998
Colon carcinoma cells use different mechanisms to escape CD95-mediated apoptosis.
    Cancer research, 1998, Feb-01, Volume: 58, Issue:3

    Topics: Antigens, Neoplasm; Apoptosis; Brefeldin A; Carcinoma; Cell Transformation, Neoplastic; Colonic Neoplasms; Cycloheximide; Cyclopentanes; Dactinomycin; Enzyme Inhibitors; Fas Ligand Protein; fas Receptor; Humans; Immunologic Capping; Interferon-gamma; Intestinal Mucosa; Membrane Glycoproteins; Nucleic Acid Synthesis Inhibitors; Phorbol Esters; Protein Kinase C; Protein Synthesis Inhibitors; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1998
The catalytic domain of PKC-epsilon, in reciprocal PKC-delta and -epsilon chimeras, is responsible for conferring tumorgenicity to NIH3T3 cells, whereas both regulatory and catalytic domains of PKC-epsilon contribute to in vitro transformation.
    Oncogene, 1998, Jan-08, Volume: 16, Issue:1

    Topics: 3T3 Cells; Animals; Catalysis; Cell Division; Cell Transformation, Neoplastic; Isoenzymes; Mice; Mice, Nude; Protein Kinase C; Protein Kinase C-delta; Protein Kinase C-epsilon; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate

1998
Two-stage exposure of Syrian-hamster-embryo cells to environmental carcinogens: superinduction of ornithine decarboxylase correlates with increase of morphological-transformation frequency.
    International journal of cancer, 1998, Mar-02, Volume: 75, Issue:5

    Topics: Animals; Benzo(a)pyrene; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Clofibrate; Cricetinae; Drug Administration Schedule; Enzyme Induction; Mesocricetus; Ornithine Decarboxylase; Tetradecanoylphorbol Acetate

1998
Phorbol 12-myristate 13-acetate can transform monocyte-derived dendritic cells to different cell types similar to those found in dermatofibroma. A possible in vitro model of the histogenesis of dermatofibroma.
    Journal of cutaneous pathology, 1998, Volume: 25, Issue:2

    Topics: Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Cytokines; Dendritic Cells; Flow Cytometry; Histiocytoma, Benign Fibrous; Humans; Immunohistochemistry; Leukocytes, Mononuclear; Lipopolysaccharide Receptors; Skin Neoplasms; Tetradecanoylphorbol Acetate

1998
Topical retinoic acid reduces skin papilloma formation but resistant papillomas are at high risk for malignant conversion.
    Cancer research, 1998, Apr-01, Volume: 58, Issue:7

    Topics: Administration, Topical; Animals; Anticarcinogenic Agents; Antineoplastic Agents; Biomarkers, Tumor; Carcinogens; Carcinoma, Basal Cell; Cell Transformation, Neoplastic; Disease Progression; Diterpenes; Female; Immunohistochemistry; Mice; Mice, Inbred BALB C; Mice, Inbred SENCAR; Papilloma; Phenotype; Precancerous Conditions; Receptors, Retinoic Acid; Retinoid X Receptors; Risk Factors; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate; Transcription Factors; Transforming Growth Factor beta; Tretinoin

1998
Overexpression of PKCepsilon in R6 fibroblasts causes increased production of active TGFbeta.
    Journal of cellular physiology, 1998, Volume: 175, Issue:3

    Topics: Animals; Cell Adhesion; Cell Division; Cell Line; Cell Transformation, Neoplastic; Culture Media, Conditioned; DNA; Fibroblasts; Isoenzymes; Mitogens; Molecular Weight; Protein Kinase C; Protein Kinase C-epsilon; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta

1998
Phase transitions in the growth of C3H 10T1/2 cells.
    Radiation research, 1998, Volume: 149, Issue:5

    Topics: Animals; Anticarcinogenic Agents; Carcinogens; Cell Cycle Proteins; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclins; Dose-Response Relationship, Radiation; Linear Energy Transfer; Mice; Mice, Inbred C3H; Microtubule-Associated Proteins; RNA, Messenger; S Phase; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Suppressor Proteins

1998
[Spontaneous reversion of tumor cells as a source of dormant metastases].
    Tsitologiia, 1998, Volume: 40, Issue:4

    Topics: Animals; Carcinogens; Cell Division; Cell Transformation, Neoplastic; Culture Media; Growth Substances; Mice; Neoplasm Metastasis; Proto-Oncogene Proteins c-jun; Sarcoma, Experimental; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Stem Cell Assay

1998
Migration induction of contact inhibited C3H 10T1/2 cells by protein kinase C (PKC) dependent process.
    Neoplasma, 1998, Volume: 45, Issue:2

    Topics: Animals; Blotting, Western; Carcinogens; Cell Movement; Cell Transformation, Neoplastic; Collagen; Contact Inhibition; Diglycerides; Enzyme Activation; Fibronectins; Integrins; MAP Kinase Kinase Kinase 1; Mice; Mice, Inbred C3H; Polymerase Chain Reaction; Protein Kinase C; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Tetradecanoylphorbol Acetate

1998
Tumor promoter induces high mobility group HMG-Y protein expression in transformation-sensitive but not -resistant cells.
    Oncogene, 1998, Jul-02, Volume: 16, Issue:26

    Topics: Alternative Splicing; Animals; Carcinogens; Cell Transformation, Neoplastic; Gene Expression Regulation, Neoplastic; Genetic Variation; High Mobility Group Proteins; HMGA1a Protein; Mice; Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factors; Transcription, Genetic

1998
Increased DNA synthesis in INIT/10T1/2 cells after exposure to a 60 Hz magnetic field: a magnetic-field or a thermal effect?
    Radiation research, 1999, Volume: 151, Issue:2

    Topics: Animals; Carcinogens; Cell Division; Cell Transformation, Neoplastic; CHO Cells; Cricetinae; DNA; Electromagnetic Fields; Fibroblasts; Hot Temperature; Humans; Jurkat Cells; Methylcholanthrene; Mice; Mice, Inbred C3H; Proto-Oncogene Proteins c-myc; Tetradecanoylphorbol Acetate; Thymidine; Tritium

1999
Expression of dominant negative Erk2 inhibits AP-1 transactivation and neoplastic transformation.
    Oncogene, 1998, Dec-31, Volume: 17, Issue:26

    Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Epidermal Cells; Epidermal Growth Factor; Gene Expression Regulation, Neoplastic; Genes, Dominant; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Mutation; Phosphorylation; Recombinant Proteins; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcriptional Activation; Transfection

1998
Effect of magnetic field exposure on anchorage-independent growth of a promoter-sensitive mouse epidermal cell line (JB6).
    Environmental health perspectives, 1999, Volume: 107, Issue:3

    Topics: Analysis of Variance; Animals; Carcinogens; Cell Division; Cell Line, Transformed; Cell Transformation, Neoplastic; Clone Cells; Cocarcinogenesis; Dose-Response Relationship, Drug; Electromagnetic Fields; Epidermal Cells; Epidermis; Epithelial Cells; Mice; Neoplasms, Radiation-Induced; Single-Blind Method; Tetradecanoylphorbol Acetate

1999
Protein kinase C expression links natural antibody binding with surveillance of activated and preneoplastic cells.
    Scandinavian journal of immunology, 1999, Volume: 49, Issue:4

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Binding Sites, Antibody; Cell Transformation, Neoplastic; Enzyme Activation; Enzyme Inhibitors; Fibroblasts; Genes, ras; Immunity, Innate; Isoenzymes; Male; Mice; Mice, Inbred C3H; Precancerous Conditions; Protein Kinase C; Protein Kinase C beta; Rats; Tetradecanoylphorbol Acetate; Tumor Stem Cell Assay

1999
Apoptosis inhibition and ornithine decarboxylase superinduction as early epigenetic events in morphological transformation of Syrian hamster embryo cells exposed to 2-methoxyacetaldehyde, a metabolite of 2-methoxyethanol.
    Toxicology letters, 1999, Mar-29, Volume: 105, Issue:2

    Topics: Acetaldehyde; Animals; Apoptosis; bcl-X Protein; Carcinogenicity Tests; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; DNA Fragmentation; Embryo, Mammalian; Enzyme Induction; Ethylene Glycols; Female; Mesocricetus; Ornithine Decarboxylase; Proto-Oncogene Proteins c-bcl-2; Teratogens; Tetradecanoylphorbol Acetate; Xenobiotics

1999
TPA induces a block of differentiation and increases the susceptibility to neoplastic transformation of a rat thyroid epithelial cell line.
    Oncology research, 1998, Volume: 10, Issue:9

    Topics: Animals; Antigens, Polyomavirus Transforming; Carcinogens; Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; Epithelial Cells; Genes, mos; Genes, ras; Genes, src; Iodide Peroxidase; Nuclear Proteins; Protein Kinase C; Rats; Rats, Inbred Strains; Receptors, Thyrotropin; Retroviridae; Tetradecanoylphorbol Acetate; Thyroglobulin; Thyroid Gland; Thyroid Nuclear Factor 1; Transcription Factors

1998
Iodide symporter gene expression in normal and transformed rat thyroid cells.
    European journal of endocrinology, 1999, Volume: 140, Issue:5

    Topics: Animals; Blotting, Northern; Carrier Proteins; Cell Transformation, Neoplastic; Colforsin; Cyclic AMP; Down-Regulation; Gene Expression Regulation; Insulin; Iodides; Iodine; Membrane Proteins; Rats; RNA, Messenger; Symporters; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin; Tumor Cells, Cultured; Up-Regulation

1999
Posttranslational regulation of Myc function in response to phorbol ester/interferon-gamma-induced differentiation of v-Myc-transformed U-937 monoblasts.
    Blood, 1999, Jun-01, Volume: 93, Issue:11

    Topics: Antineoplastic Agents; Carcinogens; Cell Differentiation; Cell Transformation, Neoplastic; Genes, myc; Humans; Interferon-gamma; Monocytes; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-myc; Tetradecanoylphorbol Acetate; U937 Cells

1999
Involvement of protein kinase Cepsilon (PKCepsilon) in thyroid cell death. A truncated chimeric PKCepsilon cloned from a thyroid cancer cell line protects thyroid cells from apoptosis.
    The Journal of biological chemistry, 1999, Aug-13, Volume: 274, Issue:33

    Topics: Amino Acid Sequence; Animals; Apoptosis; Base Sequence; Cell Transformation, Neoplastic; Chromosome Mapping; Chromosomes, Human, Pair 2; Cloning, Molecular; Humans; In Situ Hybridization, Fluorescence; Isoenzymes; Mice; Mice, Nude; Molecular Sequence Data; Protein Kinase C; Protein Kinase C-epsilon; Recombinant Proteins; Tetradecanoylphorbol Acetate; Thyroid Gland; Tumor Cells, Cultured

1999
Transgenic mice demonstrate AP-1 (activator protein-1) transactivation is required for tumor promotion.
    Proceedings of the National Academy of Sciences of the United States of America, 1999, Aug-17, Volume: 96, Issue:17

    Topics: Animals; Cell Transformation, Neoplastic; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Transgenic; Promoter Regions, Genetic; Proto-Oncogene Proteins c-jun; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcriptional Activation

1999
Effects of superoxide anion, B(alpha)P and TPA on the membrane fluidity of NIH3T3 cells.
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 1997, Volume: 19, Issue:3

    Topics: 3T3 Cells; Animals; Benzo(a)pyrene; Carcinogens; Cell Transformation, Neoplastic; Free Radicals; Membrane Fluidity; Mice; Oxygen; Tetradecanoylphorbol Acetate

1997
Tumor suppression by p27Kip1 and p21Cip1 during chemically induced skin carcinogenesis.
    Oncogene, 1999, Aug-19, Volume: 18, Issue:33

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoma; Animals; Carcinogens; Carcinoma; Cell Cycle Proteins; Cell Transformation, Neoplastic; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Cyclins; Genes, ras; Genes, Tumor Suppressor; Intestinal Neoplasms; Keratinocytes; Mice; Mice, Knockout; Microtubule-Associated Proteins; Mutation; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Suppressor Proteins

1999
A multihit, multistage model of chemical carcinogenesis.
    Carcinogenesis, 1999, Volume: 20, Issue:9

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cocarcinogenesis; DNA Mutational Analysis; DNA, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Genes, ras; Keratinocytes; Keratins; Mice; Models, Biological; Neoplasm Proteins; Papilloma; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; S Phase; Skin Neoplasms; Tetradecanoylphorbol Acetate

1999
JNK activation is required for JB6 cell transformation induced by tumor necrosis factor-alpha but not by 12-O-tetradecanoylphorbol-13-acetate.
    The Journal of biological chemistry, 1999, Oct-15, Volume: 274, Issue:42

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Enzyme Activation; JNK Mitogen-Activated Protein Kinases; Mice; Mitogen-Activated Protein Kinases; Mutation; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

1999
Antagonistic effects of protein kinase C alpha and delta on both transformation and phospholipase D activity mediated by the epidermal growth factor receptor.
    Molecular and cellular biology, 1999, Volume: 19, Issue:11

    Topics: Acetophenones; Animals; Benzopyrans; Carbazoles; Cell Transformation, Neoplastic; Cells, Cultured; Crosses, Genetic; Epidermal Growth Factor; ErbB Receptors; Indoles; Isoenzymes; Models, Genetic; Mutagenesis, Insertional; Phospholipase D; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-delta; Rats; Recombinant Proteins; Tetradecanoylphorbol Acetate

1999
Tumor promoter-induced ornithine decarboxylase gene expression occurs independently of AP-1 activation.
    Oncogene, 1999, Oct-14, Volume: 18, Issue:42

    Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Eflornithine; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Mice; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Proto-Oncogene Proteins c-jun; Tetradecanoylphorbol Acetate; Transcription Factor AP-1

1999
12-O-tetradecanoylphorbol-13-acetate promotion of transgenic mouse epidermis coexpressing transforming growth factor-alpha and v-fos: acceleration of autonomous papilloma formation and malignant conversion via c-Ha-ras activation.
    Molecular carcinogenesis, 1999, Volume: 26, Issue:4

    Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Gene Expression Regulation, Neoplastic; Genes, fos; Genes, ras; Humans; Mice; Mice, Transgenic; Oncogene Proteins v-fos; Papilloma; Proto-Oncogene Proteins p21(ras); Skin Neoplasms; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha

1999
Differentially expressed protein Pdcd4 inhibits tumor promoter-induced neoplastic transformation.
    Proceedings of the National Academy of Sciences of the United States of America, 1999, Nov-23, Volume: 96, Issue:24

    Topics: Animals; Apoptosis Regulatory Proteins; Cell Line; Cell Transformation, Neoplastic; Gene Expression; Humans; Immunoblotting; Keratinocytes; Mice; Mice, Inbred BALB C; Phenotype; Protein Biosynthesis; Proteins; Rabbits; RNA-Binding Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1999
Differential expression of the splicing regulatory factor genes during two-step chemical transformation in a BALB/3T3-derived cell line, MT-5.
    Carcinogenesis, 1999, Volume: 20, Issue:12

    Topics: 3T3 Cells; Animals; Base Sequence; Cell Line; Cell Transformation, Neoplastic; DNA Primers; Methylnitronitrosoguanidine; Mice; Mice, Inbred BALB C; Nuclear Proteins; RNA Splicing; RNA-Binding Proteins; Serine-Arginine Splicing Factors; Tetradecanoylphorbol Acetate

1999
Induction of cyclooxygenase expression and enhancement of malignant cell transformation by 2,3,7,8-tetrachlorodibenzo-p-dioxin.
    Carcinogenesis, 2000, Volume: 21, Issue:1

    Topics: Animals; Arachidonic Acid; Cell Transformation, Neoplastic; Enzyme Induction; Fibroblasts; Mice; Mice, Inbred C3H; Polychlorinated Dibenzodioxins; Prostaglandin-Endoperoxide Synthases; Prostaglandins; RNA, Messenger; Tetradecanoylphorbol Acetate

2000
Oncogenic potential of cyclin E in T-cell lymphomagenesis in transgenic mice: evidence for cooperation between cyclin E and Ras but not Myc.
    Oncogene, 1999, Dec-16, Volume: 18, Issue:54

    Topics: Animals; Cell Transformation, Neoplastic; Cyclin E; Embryo, Mammalian; Fibroblasts; Genes, myc; Genes, ras; Hyperplasia; Ionomycin; Locus Control Region; Lymphoid Tissue; Lymphoma, T-Cell; Methylnitrosourea; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Transgenic; Point Mutation; Protamine Kinase; Rats; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymus Gland

1999
Rap1-suppressed tumorigenesis is concomitant with the interference in ras effector signaling.
    FEBS letters, 2000, Feb-11, Volume: 467, Issue:2-3

    Topics: Animals; Cell Division; Cell Transformation, Neoplastic; Enzyme Activation; Epidermal Growth Factor; Humans; Insulin; Mice; Mice, Inbred BALB C; Mice, Nude; Mitogen-Activated Protein Kinases; Nerve Growth Factor; rap1 GTP-Binding Proteins; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured

2000
Screening for the in vitro anti-tumor-promoting activities of edible plants from Malaysia.
    Bioscience, biotechnology, and biochemistry, 2000, Volume: 64, Issue:1

    Topics: Antineoplastic Agents; Cell Transformation, Neoplastic; Drug Screening Assays, Antitumor; Herpesvirus 4, Human; Malaysia; Plant Extracts; Plants, Edible; Plants, Medicinal; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

2000
Enhancement of the transformed shape phenotype by microtubule inhibitors and reversal by an inhibitor combination.
    International journal of oncology, 2000, Volume: 16, Issue:4

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Colchicine; Insulin; Microtubules; Monensin; Paclitaxel; Phenotype; Rats; Tetradecanoylphorbol Acetate; Valinomycin

2000
The dominant negative Ras mutant, N17Ras, can inhibit signaling independently of blocking Ras activation.
    The Journal of biological chemistry, 2000, Mar-24, Volume: 275, Issue:12

    Topics: Cell Transformation, Neoplastic; DNA-Binding Proteins; ets-Domain Protein Elk-1; Genes, ras; Growth Substances; Guanosine Diphosphate; Guanosine Triphosphate; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Mutation; Phosphorylation; Proto-Oncogene Proteins; ras Proteins; Ribosomal Protein S6 Kinases, 90-kDa; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factors; Transcriptional Activation

2000
Differential abilities of the Raf family of protein kinases to abrogate cytokine dependency and prevent apoptosis in murine hematopoietic cells by a MEK1-dependent mechanism.
    Leukemia, 2000, Volume: 14, Issue:4

    Topics: Animals; Apoptosis; Autocrine Communication; Cell Division; Cell Line; Cell Line, Transformed; Cell Transformation, Neoplastic; Dimethyl Sulfoxide; Enzyme Activation; Estradiol; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic Stem Cells; Interleukin-3; MAP Kinase Kinase 1; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Multigene Family; Phosphorylation; Protein Isoforms; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-raf; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Transfection

2000
Effect of a tyrosine 155 to phenylalanine mutation of protein kinase cdelta on the proliferative and tumorigenic properties of NIH 3T3 fibroblasts.
    Carcinogenesis, 2000, Volume: 21, Issue:5

    Topics: 3T3 Cells; Animals; Base Sequence; Biological Transport; Cell Line; Cell Transformation, Neoplastic; DNA; Fibroblasts; Humans; Isoenzymes; Mice; Mutagenesis, Site-Directed; Phenylalanine; Protein Kinase C; Protein Kinase C-delta; Subcellular Fractions; Tetradecanoylphorbol Acetate; Tyrosine

2000
Transforming JB6 cells exhibit enhanced integrin-mediated adhesion to osteopontin.
    Journal of cellular biochemistry, 2000, Volume: 78, Issue:1

    Topics: Animals; beta-N-Acetylhexosaminidases; Cell Adhesion; Cell Line; Cell Transformation, Neoplastic; Epidermis; Integrins; Kinetics; Mice; Osteopontin; Precancerous Conditions; Receptors, Cell Surface; Sialoglycoproteins; Tetradecanoylphorbol Acetate

2000
Inhibitory effects of hydrolyzable tannins on tumor promoting activities induced by 12-O-tetradecanoyl-phorbol-13-acetate (TPA) in JB6 mouse epidermal cells.
    Basic life sciences, 1999, Volume: 66

    Topics: Animals; Anticarcinogenic Agents; Cell Transformation, Neoplastic; Cells, Cultured; Hydrolysis; Mice; Mice, Inbred BALB C; Molecular Structure; Skin; Tannins; Tetradecanoylphorbol Acetate

1999
ERK1/2 phosphorylation, induced by electromagnetic fields, diminishes during neoplastic transformation.
    Journal of cellular biochemistry, 2000, Jun-06, Volume: 78, Issue:3

    Topics: Animals; Blotting, Western; Cell Transformation, Neoplastic; Cells, Cultured; Diterpenes; DNA; Electromagnetic Fields; Electrophoresis, Agar Gel; Fibroblasts; HSP110 Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Phosphorylation; Proto-Oncogene Proteins c-fos; Retinyl Esters; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Vitamin A

2000
Aberrant cell cycle progression contributes to the early-stage accelerated carcinogenesis in transgenic epidermis expressing the dominant negative TGFbetaRII.
    Oncogene, 2000, Jul-27, Volume: 19, Issue:32

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bromodeoxyuridine; Carcinogens; Carcinoma, Squamous Cell; Carrier Proteins; Cell Cycle; Cell Cycle Proteins; Cell Transformation, Neoplastic; Centrosome; Cyclin-Dependent Kinase Inhibitor p15; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p27; Epidermal Cells; Gene Expression; Mice; Mice, Transgenic; Microtubule-Associated Proteins; Mitosis; Papilloma; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; Tetradecanoylphorbol Acetate; Time Factors; Tumor Suppressor Proteins

2000
Constitutive expression of erbB2 in epidermis of transgenic mice results in epidermal hyperproliferation and spontaneous skin tumor development.
    Oncogene, 2000, Aug-31, Volume: 19, Issue:37

    Topics: Animals; Carcinogens; Carcinoma, Squamous Cell; Cattle; Cell Differentiation; Cell Division; Cell Transformation, Neoplastic; Cocarcinogenesis; Dimerization; Disease Progression; Epidermis; ErbB Receptors; Female; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Genes, erbB-2; Genes, ras; Genes, Synthetic; Hyperplasia; Keratins; Male; Mice; Mice, Inbred ICR; Mice, Transgenic; Neoplasm Proteins; Papilloma; Phosphorylation; Promoter Regions, Genetic; Protein Processing, Post-Translational; Rats; Receptor, ErbB-2; Receptor, ErbB-3; Recombinant Fusion Proteins; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transgenes

2000
Inhibition of 12-O-tetradecanoylphorbol-13-acetate-induced NF-kappaB activation by tea polyphenols, (-)-epigallocatechin gallate and theaflavins.
    Carcinogenesis, 2000, Volume: 21, Issue:10

    Topics: Animals; Anticarcinogenic Agents; Biflavonoids; Carcinogens; Catechin; Cell Line; Cell Transformation, Neoplastic; DNA; Epidermis; Flavonoids; I-kappa B Proteins; Mice; NF-kappa B; Phenols; Phosphorylation; Polymers; Tea; Tetradecanoylphorbol Acetate; Transcriptional Activation

2000
Anti-transforming nature of ascorbic acid and its derivatives examined by two-stage cell transformation using BALB/c 3T3 cells.
    Cancer letters, 2000, Nov-10, Volume: 160, Issue:1

    Topics: 3T3 Cells; Animals; Ascorbic Acid; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Methylcholanthrene; Mice; Mice, Inbred BALB C; Tetradecanoylphorbol Acetate; Time Factors; Tumor Necrosis Factor-alpha

2000
Induced p21WAF1 expression acts to reverse myc myelomonocytic cell transformation.
    Cancer gene therapy, 2000, Volume: 7, Issue:11

    Topics: Animals; Apoptosis; Blotting, Northern; Caffeine; Carcinogens; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Dose-Response Relationship, Drug; Electrophoresis, Agar Gel; Flow Cytometry; G1 Phase; G2 Phase; Immunohistochemistry; In Situ Nick-End Labeling; Interleukin-3; Macrophage Colony-Stimulating Factor; Mice; Mitomycin; Monocytes; Nucleic Acid Synthesis Inhibitors; Oncogene Protein p55(v-myc); Phenotype; Plasmids; Polymerase Chain Reaction; Proto-Oncogene Proteins c-myc; Retroviridae; RNA, Catalytic; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Transfection; Tumor Suppressor Protein p53

2000
Tumor promoter produces anchorage independence in mouse epidermal cells by an induction mechanism.
    Carcinogenesis, 1980, Volume: 1, Issue:11

    Topics: Animals; Carcinogens; Cell Adhesion; Cell Line; Cell Transformation, Neoplastic; Epidermal Cells; Epidermis; Mice; Tetradecanoylphorbol Acetate

1980
[p53 gene mutations in mouse skin tumors induced by DMBA-TPA-MNNG].
    Zhonghua bing li xue za zhi = Chinese journal of pathology, 1998, Volume: 27, Issue:4

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Exons; Genes, p53; Methylnitronitrosoguanidine; Mice; Mice, Inbred SENCAR; Papilloma; Point Mutation; Skin Neoplasms; Tetradecanoylphorbol Acetate

1998
Investigation of the mechanism for enhancement of radiation transformation in vitro by 12-O-tetradecanoylphorbol-13-acetate.
    Carcinogenesis, 1980, Volume: 1, Issue:12

    Topics: Animals; Carcinogens; Cell Line, Transformed; Cell Transformation, Neoplastic; Cells, Cultured; Cocarcinogenesis; DNA Damage; Dose-Response Relationship, Radiation; Fibroblasts; Mice; Mice, Inbred C3H; Radiation-Sensitizing Agents; Tetradecanoylphorbol Acetate

1980
A novel transformation suppressor, Pdcd4, inhibits AP-1 transactivation but not NF-kappaB or ODC transactivation.
    Oncogene, 2001, Feb-08, Volume: 20, Issue:6

    Topics: Animals; Apoptosis Regulatory Proteins; Cell Transformation, Neoplastic; Genes, Tumor Suppressor; Mice; NF-kappa B; Ornithine Decarboxylase; Proteins; RNA-Binding Proteins; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcriptional Activation

2001
Novel tumor-promoting property of tamoxifen.
    Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 2001, Volume: 12, Issue:4

    Topics: Animals; Carcinogens; Cell Division; Cell Line; Cell Transformation, Neoplastic; Down-Regulation; Endometrial Neoplasms; Estradiol Congeners; Female; Fibroblasts; Gene Expression Regulation, Neoplastic; Genes, src; Humans; Neoplasms; Protein Kinase C; Protein Kinase C-delta; Rats; Tamoxifen; Tetradecanoylphorbol Acetate

2001
Suppression of skin tumorigenesis in c-Jun NH(2)-terminal kinase-2-deficient mice.
    Cancer research, 2001, May-15, Volume: 61, Issue:10

    Topics: Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; DNA; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinase 9; Mitogen-Activated Protein Kinases; Papilloma; Phosphorylation; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factor AP-1

2001
Transformation nonresponsive cells owe their resistance to lack of p65/nuclear factor-kappaB activation.
    Cancer research, 2001, May-15, Volume: 61, Issue:10

    Topics: Animals; Carcinogens; Cell Line; Cell Nucleus; Cell Transformation, Neoplastic; DNA; DNA-Binding Proteins; Humans; I-kappa B Proteins; Mice; NF-kappa B; NF-kappa B p50 Subunit; NF-KappaB Inhibitor alpha; Skin; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription Factor RelA; Transcriptional Activation; Tumor Necrosis Factor-alpha

2001
[Phorbol-12-myristate-13-acetate and interferon-gamma synergistic induction of B7-1 expression in ovary carcinoma cells and immunological value].
    Zhonghua fu chan ke za zhi, 1999, Volume: 34, Issue:7

    Topics: B7-1 Antigen; Cell Transformation, Neoplastic; Cystadenocarcinoma, Mucinous; Cystadenocarcinoma, Serous; Drug Synergism; Female; Humans; Interferon-gamma; Ovarian Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1999
Improvement of in vitro two-stage transformation assay and determination of the promotional effect of cadmium.
    Toxicology in vitro : an international journal published in association with BIBRA, 2001, Volume: 15, Issue:3

    Topics: 3T3 Cells; Animals; Cadmium; Carcinogenicity Tests; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; In Vitro Techniques; Methylnitronitrosoguanidine; Mice; Mice, Inbred BALB C; Polychlorinated Dibenzodioxins; Tetradecanoylphorbol Acetate; Time Factors

2001
Omega 3 but not omega 6 fatty acids inhibit AP-1 activity and cell transformation in JB6 cells.
    Proceedings of the National Academy of Sciences of the United States of America, 2001, Jun-19, Volume: 98, Issue:13

    Topics: Animals; Cell Adhesion; Cell Line; Cell Transformation, Neoplastic; Epidermal Growth Factor; Fatty Acids, Omega-3; Fatty Acids, Omega-6; Fatty Acids, Unsaturated; Genes, Reporter; JNK Mitogen-Activated Protein Kinases; Kinetics; Luciferases; Mice; Mitogen-Activated Protein Kinases; Oligodeoxyribonucleotides; p38 Mitogen-Activated Protein Kinases; Skin; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcriptional Activation; Transfection

2001
Suppression of cell transformation and induction of apoptosis by caffeic acid phenethyl ester.
    Molecular carcinogenesis, 2001, Volume: 31, Issue:2

    Topics: Animals; Apoptosis; Blotting, Western; Boron Compounds; Caffeic Acids; Carcinogens; Caspase 3; Caspases; Cell Division; Cell Line; Cell Transformation, Neoplastic; DNA Fragmentation; Dose-Response Relationship, Drug; Humans; Methacrylates; Methylmethacrylates; Mice; Phenylethyl Alcohol; Phosphorylation; Precipitin Tests; Serine; Tetradecanoylphorbol Acetate; Time Factors; Transcription, Genetic; Transfection; Tumor Suppressor Protein p53

2001
Influence of beta1 integrins on epidermal squamous cell carcinoma formation in a transgenic mouse model: alpha3beta1, but not alpha2beta1, suppresses malignant conversion.
    Cancer research, 2001, Jul-01, Volume: 61, Issue:13

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, CD; Antigens, Neoplasm; Basigin; Carcinogens; Carcinoma, Squamous Cell; Cell Division; Cell Transformation, Neoplastic; Female; Integrin alpha3beta1; Integrins; Keratinocytes; Membrane Glycoproteins; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Transgenic; Papilloma; Receptors, Collagen; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tetraspanin 28

2001
Micronucleus induction in Syrian hamster embryo cells following exposure to 50 Hz magnetic fields, benzo(a)pyrene, and TPA in vitro.
    Mutation research, 2001, Aug-22, Volume: 495, Issue:1-2

    Topics: Animals; Benzo(a)pyrene; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Dose-Response Relationship, Drug; Electromagnetic Fields; Embryo, Mammalian; Mesocricetus; Micronucleus Tests; Mitotic Index; Mutagens; Tetradecanoylphorbol Acetate

2001
Modulation of radiation induced transformation by combinations of a phorbol diester and a lymphotoxin.
    Toxicologic pathology, 1984, Volume: 12, Issue:2

    Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Embryo, Mammalian; Lymphotoxin-alpha; Mesocricetus; Neoplasms, Radiation-Induced; Tetradecanoylphorbol Acetate; Ultraviolet Rays

1984
Two novel glycosides from the fruits of Morinda citrifolia (noni) inhibit AP-1 transactivation and cell transformation in the mouse epidermal JB6 cell line.
    Cancer research, 2001, Aug-01, Volume: 61, Issue:15

    Topics: Animals; Anticarcinogenic Agents; Cell Adhesion; Cell Line; Cell Transformation, Neoplastic; DNA; Epidermal Growth Factor; Fruit; Glucosides; Glycosides; Mice; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Plant Extracts; Plants, Medicinal; Proto-Oncogene Proteins c-jun; Rubiaceae; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcriptional Activation

2001
p-Nonylphenol acts as a promoter in the BALB/3T3 cell transformation.
    Mutation research, 2001, Jun-27, Volume: 493, Issue:1-2

    Topics: 3T3 Cells; Animals; Carcinogens; Cell Transformation, Neoplastic; Cocarcinogenesis; Environmental Pollutants; Estradiol; Methylcholanthrene; Mice; Phenols; Receptors, Estrogen; Tetradecanoylphorbol Acetate

2001
Transactivation of the epidermal growth factor receptor is involved in 12-O-tetradecanoylphorbol-13-acetate-induced signal transduction.
    The Journal of biological chemistry, 2001, Dec-14, Volume: 276, Issue:50

    Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Embryo, Mammalian; Enzyme Inhibitors; ErbB Receptors; Ligands; Mice; Mitogen-Activated Protein Kinases; Models, Biological; Phenylalanine; Phosphorylation; Protein Binding; Protein Structure, Tertiary; Quinazolines; Signal Transduction; Tetradecanoylphorbol Acetate; Thiophenes; Transcription Factor AP-1; Transcriptional Activation; Tyrphostins

2001
Discrete roles of cytokines, TNF-alpha, IL-1, IL-6 in tumor promotion and cell transformation.
    International journal of oncology, 2002, Volume: 20, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Division; Cell Transformation, Neoplastic; DNA Primers; Female; Humans; Interleukin-1; Interleukin-6; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Okadaic Acid; Polymerase Chain Reaction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transfection; Tumor Necrosis Factor-alpha

2002
Regulation of the differentiation-related gene Drg-1 during mouse skin carcinogenesis.
    Molecular carcinogenesis, 2001, Volume: 32, Issue:2

    Topics: Animals; Carcinogens; Cell Cycle Proteins; Cell Differentiation; Cell Transformation, Neoplastic; Genes, ras; Intracellular Signaling Peptides and Proteins; Keratinocytes; Mice; Mice, Inbred C57BL; Papilloma; RNA, Messenger; Skin Neoplasms; Tetradecanoylphorbol Acetate

2001
Induction of cyclooxygenase-2 by tumor promoters in transformed and cytochrome P450 2E1-expressing hepatocytes.
    Carcinogenesis, 2002, Volume: 23, Issue:1

    Topics: Animals; Blotting, Western; Carcinogens; CCAAT-Enhancer-Binding Proteins; Cell Line, Transformed; Cell Transformation, Neoplastic; Chenodeoxycholic Acid; Cyclooxygenase 2; Cytochrome P-450 CYP2E1; Electrophoretic Mobility Shift Assay; Enzyme Induction; Hepatocytes; Inflammation; Isoenzymes; Mitogen-Activated Protein Kinases; NF-kappa B; Phosphatidylinositol 3-Kinases; Prostaglandin-Endoperoxide Synthases; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate

2002
Transactivation of Fra-1 and consequent activation of AP-1 occur extracellular signal-regulated kinase dependently.
    Molecular and cellular biology, 2002, Volume: 22, Issue:2

    Topics: Animals; Base Sequence; Binding Sites; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Genes, fos; Genetic Variation; Mice; Mitogen-Activated Protein Kinases; Plasmids; Protein Structure, Tertiary; Proto-Oncogene Proteins c-fos; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcriptional Activation

2002
Ser-10 phosphorylation of histone H3 and immediate early gene expression in oncogene-transformed mouse fibroblasts.
    Cancer research, 2002, Jan-01, Volume: 62, Issue:1

    Topics: 3T3 Cells; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Transformation, Neoplastic; Epidermal Growth Factor; Fibroblasts; Gene Expression Regulation; Genes, fos; Genes, Immediate-Early; Histones; MAP Kinase Signaling System; Mice; Phosphorylation; ras Proteins; Ribosomal Protein S6 Kinases; Ribosomal Protein S6 Kinases, 90-kDa; Serine; Tetradecanoylphorbol Acetate; Urokinase-Type Plasminogen Activator

2002
Antileukemia activity of perillyl alcohol (POH): uncoupling apoptosis from G0/G1 arrest suggests that the primary effect of POH on Bcr/Abl-transformed cells is to induce growth arrest.
    Leukemia, 2002, Volume: 16, Issue:2

    Topics: Amiloride; Animals; Apoptosis; Cell Line, Transformed; Cell Transformation, Neoplastic; Cytoplasm; DNA Fragmentation; Enzyme Inhibitors; Fusion Proteins, bcr-abl; G1 Phase; Hematopoietic Stem Cells; Hydrogen-Ion Concentration; Interleukin-3; Lovastatin; Membrane Lipids; Mice; Monoterpenes; Naphthalenes; Neoplastic Stem Cells; Phosphatidylserines; Phosphorylation; Protein Processing, Post-Translational; Recombinant Fusion Proteins; Resting Phase, Cell Cycle; Signal Transduction; Sodium-Hydrogen Exchangers; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate

2002
Tumour promoter alone induces neoplastic transformation of fibroblasts from humans genetically predisposed to cancer.
    Nature, 1979, Dec-06, Volume: 282, Issue:5739

    Topics: Animals; Cell Adhesion; Cell Transformation, Neoplastic; Eye; Humans; Mice; Mice, Nude; Multiple Endocrine Neoplasia; Neoplasm Transplantation; Neoplasms, Experimental; Phorbols; Tetradecanoylphorbol Acetate

1979
Specificity of response in hamster cells induced to produce plasminogen activator by the tumor promoter, 12-O-tetradecanoylphorbol-13-acetate.
    Cancer research, 1978, Volume: 38, Issue:11 Pt 1

    Topics: Animals; Antibodies; Cell Transformation, Neoplastic; Cricetinae; Epitopes; Immunoglobulin G; Lung; Organ Specificity; Phorbols; Plasminogen Activators; Simian virus 40; Tetradecanoylphorbol Acetate

1978
Two-stage (initiation-promotion) carcinogenesis in vivo and in vitro.
    Bulletin du cancer, 1978, Volume: 65, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzopyrenes; Cell Transformation, Neoplastic; Cells, Cultured; Cocarcinogenesis; Croton Oil; Female; In Vitro Techniques; Mice; Models, Biological; Neoplasms, Experimental; Rats; Skin Neoplasms; Tetradecanoylphorbol Acetate

1978
Phenotypic properties and tumor promotor-induced alterations in rat embryo cells transformed by adenovirus.
    Cancer research, 1979, Volume: 39, Issue:8

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoviruses, Human; Animals; Benzopyrenes; Cell Aggregation; Cell Division; Cell Transformation, Neoplastic; Cell Transformation, Viral; Clone Cells; Cocarcinogenesis; Concanavalin A; Embryo, Mammalian; Membrane Proteins; Phenotype; Phorbols; Plasminogen Activators; Rats; Tetradecanoylphorbol Acetate

1979
Tumor persistence and regression in skin carcinogenesis. An experimental study.
    Zeitschrift fur Krebsforschung und klinische Onkologie. Cancer research and clinical oncology, 1978, Volume: 91, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Female; Mice; Neoplasm Regression, Spontaneous; Neoplasms, Experimental; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors

1978
The effect of phorbol diesters on chicken embryo fibroblasts.
    Cancer research, 1977, Volume: 37, Issue:9

    Topics: Animals; Avian Sarcoma Viruses; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Chick Embryo; Deoxyglucose; Fibroblasts; Mitosis; Models, Biological; Phorbol Esters; Phorbols; Sarcoma, Experimental; Tetradecanoylphorbol Acetate; Time Factors; Tumor Virus Infections

1977
Metabolism of acetylcholine receptor in chick embryo muscle cells: effects of RSV and PMA.
    Cell, 1978, Volume: 15, Issue:4

    Topics: Animals; Avian Sarcoma Viruses; Cell Survival; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Chick Embryo; Culture Media; Defective Viruses; Kinetics; Membrane Proteins; Muscles; Phorbols; Receptors, Cholinergic; Tetradecanoylphorbol Acetate

1978
Plasminogen activator in chick embryo muscle cells: induction of enzyme by RSV, PMA and retinoic acid.
    Cell, 1978, Volume: 15, Issue:4

    Topics: Animals; Avian Sarcoma Viruses; Bucladesine; Cell Differentiation; Cell Fusion; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; Chick Embryo; Cholera Toxin; Muscles; Phorbols; Plasminogen Activators; Tetradecanoylphorbol Acetate; Tretinoin; Vitamin A

1978
Is the product of the src gene a promoter?
    Proceedings of the National Academy of Sciences of the United States of America, 1979, Volume: 76, Issue:1

    Topics: Avian Sarcoma Viruses; Cell Transformation, Neoplastic; Cell Transformation, Viral; Deoxyglucose; DNA; Genes, Viral; Models, Biological; Phorbols; Tetradecanoylphorbol Acetate

1979
Modulation of plasminogen activator synthesis in chick embryo fibroblasts by cyclic nucleotides and phorobol myristate acetate.
    Cancer research, 1979, Volume: 39, Issue:5

    Topics: Animals; Avian Sarcoma Viruses; Bucladesine; Cell Transformation, Neoplastic; Cells, Cultured; Chick Embryo; Cholera Toxin; Cyclic AMP; Fibroblasts; Phorbols; Plasminogen Activators; Tetradecanoylphorbol Acetate

1979
Decrease in collagen production in normal and Rous sarcoma virus-transformed chick embryo fibroblasts induced by phorbol myristate acetate.
    Cancer research, 1979, Volume: 39, Issue:5

    Topics: Animals; Avian Sarcoma Viruses; Cell Differentiation; Cell Transformation, Neoplastic; Cells, Cultured; Chick Embryo; Collagen; Dimethyl Sulfoxide; Fibroblasts; Phorbols; Tetradecanoylphorbol Acetate

1979
The roles of the simian virus 40 tumor antigens in transformation of Chinese hamster lung cells.
    Cell, 1979, Volume: 17, Issue:3

    Topics: Animals; Antigens, Neoplasm; Antigens, Viral; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Lung; Mice; Mice, Nude; Mutation; Neoplasm Transplantation; Neoplasms, Experimental; Simian virus 40; Tetradecanoylphorbol Acetate; Transplantation, Heterologous

1979
T-antigen expression in proliferating and non-proliferating simian virus 40-transformed mouse cells.
    Journal of virology, 1979, Volume: 30, Issue:3

    Topics: Animals; Antigens, Viral; Cell Cycle; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cycloheximide; Cytarabine; Dactinomycin; DNA, Viral; Mice; Simian virus 40; Temperature; Tetradecanoylphorbol Acetate

1979
Relationship between Rous sarcoma virus-induced expression of membrane antigen and phenotypic transformation.
    Cancer research, 1979, Volume: 39, Issue:11

    Topics: Animals; Antigens, Surface; Antigens, Viral; Avian Sarcoma Viruses; Bucladesine; Cell Line; Cell Transformation, Neoplastic; Cricetinae; Genes; Phenotype; Tetradecanoylphorbol Acetate

1979
Interactions between adenovirus, a tumor promoter, and chemical carcinogens in transformation of rat embryo cell cultures.
    Proceedings of the National Academy of Sciences of the United States of America, 1978, Volume: 75, Issue:5

    Topics: Adenoviruses, Human; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Cocarcinogenesis; Phorbols; Polycyclic Compounds; Tetradecanoylphorbol Acetate; Time Factors

1978
Tumor promoter induces sister chromatid exchanges: relevance to mechanisms of carcinogenesis.
    Proceedings of the National Academy of Sciences of the United States of America, 1978, Volume: 75, Issue:12

    Topics: Cell Line; Cell Transformation, Neoplastic; Chromatids; Chromosome Aberrations; Chromosomes; Crossing Over, Genetic; Fluocinolone Acetonide; Leupeptins; Phorbols; Recombination, Genetic; Structure-Activity Relationship; Tetradecanoylphorbol Acetate

1978
Tumor promoters: carcinogenesis gets more complicated.
    Science (New York, N.Y.), 1978, Aug-11, Volume: 201, Issue:4355

    Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Cocarcinogenesis; Dietary Fats; Epidermal Growth Factor; Humans; Neoplasms; Ornithine Decarboxylase; Phenobarbital; Plasminogen Activators; Receptors, Drug; Saccharin; Smoking; Tetradecanoylphorbol Acetate

1978
Tumor promoters and epidermal growth factor stimulate anchorage-independent growth of adenovirus-tranformed rat embryo cells.
    Cell, 1979, Volume: 18, Issue:3

    Topics: Adenoviruses, Human; Animals; Cell Adhesion; Cell Division; Cell Transformation, Neoplastic; Clone Cells; Dexamethasone; Diterpenes; Embryo, Mammalian; Epidermal Growth Factor; Peptides; Phorbols; Protease Inhibitors; Rats; Tetradecanoylphorbol Acetate; Tretinoin

1979
Epidermal intercellular relationships during carcinogenesis and cocarcinogenesis as revealed by scanning electron microscopy.
    Virchows Archiv. B, Cell pathology, 1977, Sep-15, Volume: 24, Issue:4

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Autoradiography; Cell Transformation, Neoplastic; Cocarcinogenesis; Epithelium; Extracellular Space; Female; Hyperplasia; Intercellular Junctions; Mice; Microscopy, Electron, Scanning; Skin; Tetradecanoylphorbol Acetate

1977
DNA repair and malignant transformation: effect of X irradiation, 12-O-tetradecanoyl-phorbol-13-acetate, and protease inhibitors on transformation and sister-chromatid exchanges in mouse 10T 1/2 cells.
    Radiation research, 1979, Volume: 79, Issue:2

    Topics: Animals; Antipain; Cell Survival; Cell Transformation, Neoplastic; Chromosome Aberrations; DNA Repair; Dose-Response Relationship, Radiation; In Vitro Techniques; Leupeptins; Mice; Phorbols; Protease Inhibitors; Sister Chromatid Exchange; Tetradecanoylphorbol Acetate; X-Rays

1979
Tumour promoter induces anchorage independence irreversibly.
    Nature, 1979, Oct-18, Volume: 281, Issue:5732

    Topics: Animals; Antigens, Surface; Cell Adhesion; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Dose-Response Relationship, Drug; Epidermal Cells; Epidermis; Mice; Phorbol Esters; Phorbols; Structure-Activity Relationship; Tetradecanoylphorbol Acetate

1979
Effects of tumor-promoting phorbol diesters on hamster cells in culture.
    Progress in experimental tumor research, 1979, Volume: 24

    Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; DNA; Embryo, Mammalian; Enzyme Induction; Inactivation, Metabolic; Mesocricetus; Mice; Ornithine Decarboxylase; Phorbol Esters; Phorbols; Skin; Tetradecanoylphorbol Acetate

1979
Effects of promoters on DNA synthesis in C3H/10T1/2 mouse fibroblasts.
    Cancer research, 1977, Volume: 37, Issue:9

    Topics: Animals; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; DNA; Fibroblasts; Methylcholanthrene; Mice; Phorbol Esters; Phorbols; Tetradecanoylphorbol Acetate; Thymidine

1977
Effects of a tumor-promoting agent on chondrogenesis.
    The American journal of anatomy, 1977, Volume: 150, Issue:1

    Topics: Animals; Carcinogens; Cartilage; Cell Division; Cell Line; Cell Transformation, Neoplastic; Chickens; Phorbols; Proteoglycans; Tetradecanoylphorbol Acetate

1977
Enhancement of X-ray transformation by 12-O-tetradecanoyl-phorbol-13-acetate in a cloned line of C3H mouse embryo cells.
    Cancer research, 1978, Volume: 38, Issue:2

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Clone Cells; Dose-Response Relationship, Radiation; In Vitro Techniques; Mice; Mice, Inbred C3H; Neoplasms, Radiation-Induced; Phorbols; Tetradecanoylphorbol Acetate; Time Factors

1978
Correlation of anchorage-independent growth with tumorigenicity of chemically transformed mouse epidermal cells.
    Cancer research, 1978, Volume: 38, Issue:3

    Topics: Agar; Animals; Cell Adhesion; Cell Division; Cell Transformation, Neoplastic; Clone Cells; Methylnitronitrosoguanidine; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Neoplasms, Experimental; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transplantation, Isogeneic

1978
A cell culture bioassay to analyze metabolism of phorbol diester tumor promoters.
    Cancer research, 1978, Volume: 38, Issue:8

    Topics: Animals; Carboxy-Lyases; Cell Transformation, Neoplastic; Cells, Cultured; Chick Embryo; Chromatography, Thin Layer; Cricetinae; Fibroblasts; Humans; Mice; Ornithine Decarboxylase; Phorbol Esters; Phorbols; Rats; Species Specificity; Tetradecanoylphorbol Acetate

1978
Mechanism of growth arrest of chemically transformed cells in culture.
    Cancer research, 1978, Volume: 38, Issue:9

    Topics: Amino Acids; Cell Cycle; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Culture Media; DNA, Neoplasm; Glucose; Growth Substances; Tetradecanoylphorbol Acetate; Thymidine; Time Factors

1978
Enhancement of oncogenesis in C3H/10T1/2 mouse embryo cell cultures by saccharin.
    Science (New York, N.Y.), 1978, Sep-22, Volume: 201, Issue:4361

    Topics: Animals; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Cocarcinogenesis; Embryo, Mammalian; Methylcholanthrene; Mice; Mice, Inbred C3H; Saccharin; Tetradecanoylphorbol Acetate

1978
Establishment of epithelial cell lines following exposure of cultured tracheal epithelium to 12-O-tetradecanoyl-phorbol-13-acetate.
    Cancer research, 1978, Volume: 38, Issue:10

    Topics: Animals; Cell Division; Cell Line; Cell Transformation, Neoplastic; Epithelium; Phorbols; Rats; Tetradecanoylphorbol Acetate; Time Factors; Trachea

1978
Ultraviolet light in the oncogenic transformation of cultured C3H/10T1/2 mouse embryo cells.
    National Cancer Institute monograph, 1978, Issue:50

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Cocarcinogenesis; Dose-Response Relationship, Radiation; Embryo, Mammalian; Fibroblasts; Mice; Tetradecanoylphorbol Acetate; Time Factors; Ultraviolet Rays

1978
Two-stage malignant transformation in hamster embryo cells.
    British journal of cancer, 1979, Volume: 39, Issue:1

    Topics: Agar; Animals; Benz(a)Anthracenes; Cell Transformation, Neoplastic; Cricetinae; Methylcholanthrene; Neoplasm Transplantation; Neoplasms, Experimental; Phorbols; Tetradecanoylphorbol Acetate; Time Factors

1979
Two-stage chemical oncogenesis in cultures of C3H/10T1/2 cells.
    Cancer research, 1976, Volume: 36, Issue:7 PT 1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Benzopyrenes; Cell Transformation, Neoplastic; Cells, Cultured; Drug Administration Schedule; Methylcholanthrene; Phorbol Esters; Phorbols; Tetradecanoylphorbol Acetate

1976
Ornithine decarboxylase induction and DNA synthesis in hamster embryo cell cultures treated with tumor-promoting phorbol diesters.
    Cancer research, 1977, Volume: 37, Issue:11

    Topics: Carboxy-Lyases; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; DNA; Enzyme Induction; Ornithine Decarboxylase; Phorbols; Putrescine; Spermidine; Spermine; Tetradecanoylphorbol Acetate

1977
Effect of a phorbol ester on a transformation-sensitive surface protein of chick fibroblasts.
    Nature, 1976, Dec-02, Volume: 264, Issue:5585

    Topics: Animals; Cell Division; Cell Membrane; Cell Transformation, Neoplastic; Cells, Cultured; Chick Embryo; Fibroblasts; Membrane Proteins; Phorbols; Tetradecanoylphorbol Acetate; Time Factors

1976
Tumour promotor induces plasminogen activator.
    Nature, 1976, Jan-22, Volume: 259, Issue:5540

    Topics: Cell Transformation, Neoplastic; Fibroblasts; HeLa Cells; Phorbols; Plasminogen Activators; Tetradecanoylphorbol Acetate

1976
Embryonic stem (ES) cells lacking functional c-jun: consequences for growth and differentiation, AP-1 activity and tumorigenicity.
    Oncogene, 1992, Volume: 7, Issue:12

    Topics: Alleles; Animals; Base Sequence; Cell Differentiation; Cell Division; Cell Line; Cell Transformation, Neoplastic; Chloramphenicol O-Acetyltransferase; DNA; Embryo, Mammalian; Gene Expression; Genes, jun; Genetic Vectors; Mice; Mice, Inbred Strains; Molecular Sequence Data; Neoplasm Transplantation; Oligodeoxyribonucleotides; Polymerase Chain Reaction; Proto-Oncogene Proteins c-jun; Restriction Mapping; RNA; Stem Cells; Teratoma; Tetradecanoylphorbol Acetate; Transfection

1992
Expression of genes encoding type IV collagen-degrading metalloproteinases and tissue inhibitors of metalloproteinases in various human tumor cells.
    Oncogene, 1992, Volume: 7, Issue:1

    Topics: Cell Transformation, Neoplastic; Fibroblasts; Gene Expression Regulation, Enzymologic; Glycoproteins; Humans; Matrix Metalloproteinase 9; Microbial Collagenase; Neoplasms; RNA, Messenger; Tetradecanoylphorbol Acetate; Tissue Inhibitor of Metalloproteinases; Tumor Cells, Cultured

1992
Expression of high affinity binding sites for erythropoietin on L8057 cells, a mouse megakaryoblastic cell line, associated with cell differentiation.
    American journal of hematology, 1992, Volume: 39, Issue:1

    Topics: Acetylcholinesterase; Animals; Antigens; Cell Differentiation; Cell Transformation, Neoplastic; DNA, Neoplasm; Erythropoietin; Iodine Radioisotopes; Leucine; Leukemia, Experimental; Leukemia, Megakaryoblastic, Acute; Megakaryocytes; Mice; Platelet Membrane Glycoproteins; Protein Binding; Receptors, Cell Surface; Receptors, Erythropoietin; Recombinant Proteins; Tetradecanoylphorbol Acetate; Thymidine; Tumor Cells, Cultured

1992
A tobacco-specific N-nitrosamine or cigarette smoke condensate causes neoplastic transformation of xenotransplanted human bronchial epithelial cells.
    Proceedings of the National Academy of Sciences of the United States of America, 1992, Aug-01, Volume: 89, Issue:15

    Topics: Animals; Biomarkers, Tumor; Bronchi; Carcinogens; Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; Chemotaxis; Epithelium; ErbB Receptors; Gelatinases; Humans; Isoenzymes; Lung Neoplasms; Mice; Mice, Nude; Neoplasm Invasiveness; Nitrosamines; Pepsin A; Rats; Smoke; Smoking; Tetradecanoylphorbol Acetate; Trachea; Transforming Growth Factor alpha; Transplantation, Heterologous

1992
Phospholipase D activity in nontransformed and transformed fibroblasts.
    Biochimica et biophysica acta, 1992, Aug-19, Volume: 1127, Issue:3

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Cell-Free System; Fibroblasts; Kinetics; Lipid Metabolism; Lipids; Myristic Acid; Myristic Acids; Phospholipase D; Rats; Simian virus 40; Tetradecanoylphorbol Acetate

1992
Interleukin 1 alpha mediated inhibition of myogenic terminal differentiation: increased sensitivity of Ha-ras transformed cultures.
    Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1992, Volume: 3, Issue:4

    Topics: Actins; Animals; Cell Differentiation; Cell Line, Transformed; Cell Transformation, Neoplastic; Depression, Chemical; Fibroblasts; Gene Expression Regulation, Neoplastic; Interleukin-1; Mice; Mice, Inbred C3H; Muscle Proteins; Muscles; MyoD Protein; Myogenin; Nuclear Proteins; Phosphoproteins; Protein Kinase C; Proto-Oncogene Proteins p21(ras); Tetradecanoylphorbol Acetate

1992
The SH2 and SH3 domain-containing Nck protein is oncogenic and a common target for phosphorylation by different surface receptors.
    Molecular and cellular biology, 1992, Volume: 12, Issue:12

    Topics: 3T3 Cells; Adaptor Proteins, Signal Transducing; Animals; Cell Line; Cell Transformation, Neoplastic; Epidermal Growth Factor; Humans; Mice; Oncogene Proteins; Organ Specificity; Phosphorylation; Platelet-Derived Growth Factor; Precipitin Tests; Protein-Tyrosine Kinases; Rats; Receptors, Cell Surface; Signal Transduction; Sulfhydryl Compounds; Tetradecanoylphorbol Acetate; Transfection; Vanadates

1992
Effect of TPA, okadaic acid and 1 alpha,25-dihydroxyvitamin D3 on neoplastic transformation induced by 60Co gamma-rays or 252Cf fission neutrons in Balb/c 3T3 cells.
    International journal of radiation biology, 1992, Volume: 61, Issue:2

    Topics: 3T3 Cells; Animals; Calcitriol; Cell Transformation, Neoplastic; Ethers, Cyclic; Gamma Rays; Mice; Mice, Inbred BALB C; Neutrons; Okadaic Acid; Tetradecanoylphorbol Acetate

1992
Development of an in vitro model to study carcinogen-induced neoplastic progression of initiated mouse epidermal cells.
    Cancer research, 1992, Jun-01, Volume: 52, Issue:11

    Topics: Animals; Animals, Newborn; Base Sequence; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cells, Cultured; Epidermal Cells; Epidermis; Genes, ras; Keratinocytes; Keratins; Methylnitronitrosoguanidine; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Oligodeoxyribonucleotides; Papilloma; Polymerase Chain Reaction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transfection

1992
Transcripts encoding protein kinase C-alpha, -delta, -epsilon, -zeta, and -eta are expressed in basal and differentiating mouse keratinocytes in vitro and exhibit quantitative changes in neoplastic cells.
    Molecular carcinogenesis, 1992, Volume: 5, Issue:4

    Topics: Animals; Animals, Newborn; Blotting, Northern; Calcium; Cell Differentiation; Cell Transformation, Neoplastic; Cells, Cultured; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Genes, ras; Humans; Isoenzymes; Keratinocytes; Mice; Poly A; Protein Kinases; RNA; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured

1992
Spontaneous malignant transformation of melanocytes explanted from Wf/Wf mice with a Kit kinase-domain mutation.
    Proceedings of the National Academy of Sciences of the United States of America, 1992, Aug-15, Volume: 89, Issue:16

    Topics: Animals; Base Sequence; Cell Death; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Genes, Dominant; Genotype; Melanocytes; Melanoma, Experimental; Mice; Mice, Inbred C3H; Mice, Mutant Strains; Molecular Sequence Data; Mutation; Oligodeoxyribonucleotides; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-kit; Proto-Oncogenes; Skin Neoplasms; Tetradecanoylphorbol Acetate

1992
Absence of PDGF-induced, PKC-independent c-fos expression in a chemically transformed C3H/10T1/2 cell clone.
    Experimental cell research, 1992, Volume: 202, Issue:1

    Topics: Adenosine Triphosphate; Animals; Blotting, Northern; Cell Transformation, Neoplastic; Clone Cells; Deoxycytosine Nucleotides; DNA Probes; DNA Replication; Genes, fos; Kinetics; Mice; Mice, Inbred C3H; Phosphorus Radioisotopes; Platelet-Derived Growth Factor; Protein Kinase C; Receptors, Cell Surface; Receptors, Platelet-Derived Growth Factor; RNA; RNA, Messenger; Swine; Tetradecanoylphorbol Acetate; Thymidine

1992
Effect of cAMP elevating compounds on inhibition of gap junctional communication and induction of morphological transformation in Syrian hamster embryo cells.
    Carcinogenesis, 1992, Volume: 13, Issue:10

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Cell Communication; Cell Transformation, Neoplastic; Cells, Cultured; Cholera Toxin; Colforsin; Cricetinae; Cyclic AMP; Embryo, Mammalian; Intercellular Junctions; Mesocricetus; Tetradecanoylphorbol Acetate; Theophylline

1992
Analysis of temperature-sensitive functions of Fos: lack of a correlation between transformation and TRE-dependent trans-activation.
    Oncogene, 1992, Volume: 7, Issue:10

    Topics: Cell Transformation, Neoplastic; DNA; Gene Expression; HeLa Cells; Humans; Mutation; Oncogene Proteins v-fos; Proto-Oncogene Proteins c-jun; Temperature; Tetradecanoylphorbol Acetate; Transcriptional Activation

1992
Carba-prostacyclin inhibits 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced transformation in sensitive murine epidermal JB6 cells.
    Carcinogenesis, 1992, Volume: 13, Issue:10

    Topics: Animals; Cell Adhesion; Cell Transformation, Neoplastic; Cells, Cultured; Epidermal Cells; Epidermis; Epoprostenol; Kinetics; Mice; Sensitivity and Specificity; Stem Cells; Tetradecanoylphorbol Acetate

1992
Cell-transforming potential of low-density lipoproteins.
    Carcinogenesis, 1992, Volume: 13, Issue:10

    Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Fibroblasts; Lipoproteins, HDL; Lipoproteins, LDL; Methylcholanthrene; Mice; Mice, Inbred C3H; Tetradecanoylphorbol Acetate

1992
Transformation of non-tumorigenic osteoblast-like human osteosarcoma cells by hexavalent chromates: alteration of morphology, induction of anchorage-independence and proteolytic function.
    Carcinogenesis, 1992, Volume: 13, Issue:11

    Topics: Animals; Carcinogens; Cell Adhesion; Cell Division; Cell Survival; Cell Transformation, Neoplastic; Chromates; Electrochemistry; Humans; Hydrolysis; Male; Methylcholanthrene; Mice; Mice, Nude; Neoplasms, Experimental; Osteoblasts; Osteosarcoma; Plasminogen Activators; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Urokinase-Type Plasminogen Activator

1992
Transformed growth phenotype of mouse mammary epithelium in primary culture induced by specific fetal mesenchymes.
    Journal of cellular physiology, 1992, Volume: 153, Issue:2

    Topics: Animals; Cell Transformation, Neoplastic; Culture Techniques; Cytological Techniques; Epithelial Cells; Epithelium; Fetal Tissue Transplantation; Mammary Glands, Animal; Mesoderm; Mice; Mice, Inbred BALB C; Phenotype; Sepharose; Stem Cells; Stromal Cells; Tetradecanoylphorbol Acetate

1992
AP-1 (Fos-Jun) regulation by IP-1: effect of signal transduction pathways and cell growth.
    Oncogene, 1992, Volume: 7, Issue:11

    Topics: 3T3 Cells; Animals; Blood Physiological Phenomena; Calcium; Cell Transformation, Neoplastic; Cycloheximide; DNA; Genes, fos; Genes, jun; Humans; Mice; Protein Kinase C; Protein Kinases; Proteins; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-jun; Signal Transduction; Tetradecanoylphorbol Acetate; Tretinoin

1992
Differential induction of c-fos and c-jun proto-oncogenes and AP-1 activity by tumor promoter 12-O-tetradecanoyl phorbol 13-acetate in cells at different stages of tumor promotion in vitro.
    Oncogene, 1992, Volume: 7, Issue:11

    Topics: Animals; Base Sequence; Cell Transformation, Neoplastic; Cells, Cultured; DNA; Down-Regulation; Gene Expression Regulation; Genes, fos; Mice; Molecular Sequence Data; Protein Kinase C; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Proto-Oncogenes; Tetradecanoylphorbol Acetate

1992
Identification and quantification of a carcinogen-induced molecular initiation event in cell transformation.
    Oncogene, 1992, Volume: 7, Issue:11

    Topics: 3T3 Cells; 9,10-Dimethyl-1,2-benzanthracene; Animals; Base Sequence; Carcinogens; Cell Transformation, Neoplastic; Gene Expression; Genes, ras; Mice; Molecular Sequence Data; Mutation; Tetradecanoylphorbol Acetate

1992
Malignant transformation of human melanocytes: induction of a complete melanoma phenotype and genotype.
    Oncogene, 1992, Volume: 7, Issue:11

    Topics: 3T3 Cells; Animals; Antigens, Surface; Cell Transformation, Neoplastic; Chromosome Aberrations; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 6; Genes, ras; Genotype; HLA-DR Antigens; Humans; Melanocytes; Melanoma; Mice; Phenotype; Tetradecanoylphorbol Acetate

1992
Role of the 21-kDa protein TIMP-3 in oncogenic transformation of cultured chicken embryo fibroblasts.
    Proceedings of the National Academy of Sciences of the United States of America, 1992, Nov-15, Volume: 89, Issue:22

    Topics: Animals; Cell Adhesion; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Chick Embryo; Extracellular Matrix; Fibroblasts; Histones; Metalloendopeptidases; Models, Biological; Molecular Weight; Neoplasm Proteins; Tetradecanoylphorbol Acetate; Tissue Inhibitor of Metalloproteinase-3

1992
12-O-tetradecanoylphorbol-13-acetate--induced levels of AP-1 proteins: a 46-kDa protein immunoprecipitated by anti-fra-1 and induced in promotion-resistant but not promotion-sensitive JB6 cells.
    Molecular carcinogenesis, 1992, Volume: 6, Issue:3

    Topics: Amino Acid Sequence; Animals; Cell Line; Cell Transformation, Neoplastic; Electrophoresis, Polyacrylamide Gel; Gene Expression Regulation, Neoplastic; Mice; Molecular Sequence Data; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors; Transcriptional Activation

1992
Epigenetic activation of Gi-2 protein, the product of a putative protooncogene, mediates tumor promotion in vitro.
    Carcinogenesis, 1992, Volume: 13, Issue:12

    Topics: Adrenal Gland Neoplasms; Amino Acid Sequence; Animals; Cell Transformation, Neoplastic; Cells, Cultured; Epidermal Growth Factor; Female; GTP-Binding Proteins; Mice; Molecular Sequence Data; Mutation; Ovarian Neoplasms; Pertussis Toxin; Phenotype; Phospholipases A; Phospholipases A2; Proto-Oncogene Proteins; Rats; Sequence Homology, Amino Acid; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha; Virulence Factors, Bordetella

1992
Phenotypic expression of carcinogen-initiated epidermal cells to tumor cells by 12-O-tetradecanoylphorbol-13-acetate in a manner dependent on 3T3 fibroblast-derived humoral factor(s).
    Carcinogenesis, 1992, Volume: 13, Issue:8

    Topics: 3T3 Cells; 9,10-Dimethyl-1,2-benzanthracene; Animals; Calcium; Cell Transformation, Neoplastic; Cells, Cultured; Epidermis; Macrophages; Mice; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors

1992
Differential c-jun expression in response to tumor promoters in JB6 cells sensitive or resistant to neoplastic transformation.
    Molecular carcinogenesis, 1992, Volume: 5, Issue:1

    Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Epidermal Growth Factor; Gene Expression; Genes, fos; Genes, jun; In Vitro Techniques; Mice; Neoplasm Transplantation; Proto-Oncogene Proteins c-jun; RNA, Messenger; Tetradecanoylphorbol Acetate

1992
Dissociation of nuclear events on p21 RAS transformation of FDC-P1 myeloid cells: c-jun/AP-1 expression versus c-myc transcription.
    Blood, 1992, May-01, Volume: 79, Issue:9

    Topics: Cell Line; Cell Nucleus; Cell Transformation, Neoplastic; Enhancer Elements, Genetic; Enzyme Activation; Genes, myc; Humans; Interleukin-3; Protein Kinase C; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Proto-Oncogene Proteins p21(ras); Tetradecanoylphorbol Acetate; Transcription, Genetic

1992
Differential induction of 15 and 16 kDa nuclear proteins in promotion sensitive and promotion resistant mouse JB6 cells.
    Oncology research, 1992, Volume: 4, Issue:1

    Topics: Animals; Carcinogens; Cell Line; Cell Transformation, Neoplastic; In Vitro Techniques; Mice; Molecular Weight; Nuclear Proteins; Tetradecanoylphorbol Acetate

1992
Transformation and transactivation suppressor activity of the c-Jun leucine zipper fused to a bacterial repressor.
    Proceedings of the National Academy of Sciences of the United States of America, 1992, May-15, Volume: 89, Issue:10

    Topics: 3T3 Cells; Amino Acid Sequence; Animals; Bacterial Proteins; Cell Transformation, Neoplastic; Chloramphenicol O-Acetyltransferase; Choriocarcinoma; Escherichia coli; Genes, ras; Genes, Regulator; Humans; Leucine Zippers; Mice; Mutagenesis; Proto-Oncogene Proteins c-jun; Recombinant Fusion Proteins; Repressor Proteins; Restriction Mapping; Serine Endopeptidases; Suppression, Genetic; Tetradecanoylphorbol Acetate; Transfection

1992
Monoclonal anti-melanoma antibodies IKH-1 and IKH-2 which work on formalin-fixed, paraffin embedded tissues: characterization, clinical trials and comparative studies with HMB-45.
    Journal of dermatological science, 1992, Volume: 3, Issue:1

    Topics: Animals; Antibodies, Monoclonal; Antigens, Neoplasm; Biomarkers, Tumor; Cell Transformation, Neoplastic; Clinical Trials as Topic; Formaldehyde; Humans; Hybridomas; Immunohistochemistry; Melanoma; Melanoma, Experimental; Mice; Microscopy, Immunoelectron; Paraffin; Tetradecanoylphorbol Acetate; Tissue Fixation; Tumor Cells, Cultured

1992
Temporal relationships between induced changes in c-myc mRNA abundance, proliferation, and differentiation in HL60 cells.
    Differentiation; research in biological diversity, 1992, Volume: 49, Issue:2

    Topics: Cell Differentiation; Cell Division; Cell Transformation, Neoplastic; Dimethyl Sulfoxide; Down-Regulation; Granulocytes; Humans; Leukemia, Experimental; Leukemia, Myeloid; Proto-Oncogene Proteins c-myc; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1992
Human smooth muscle myosin light chain-2 gene expression is repressed in ras transformed fibroblast cells.
    Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1992, Volume: 3, Issue:1

    Topics: Cell Line, Transformed; Cell Transformation, Neoplastic; Fibroblasts; Gene Expression Regulation, Neoplastic; Genes, ras; Humans; Muscle, Smooth; Myosins; RNA, Messenger; Stereoisomerism; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1992
Studies on the mechanisms of HTLV-I leukemogenesis.
    Leukemia, 1992, Volume: 6 Suppl 3

    Topics: Cell Transformation, Neoplastic; DNA Damage; Genes, pX; HTLV-I Infections; Humans; Leukemia, T-Cell; Methylation; Micronucleus Tests; Plasmids; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Tumor Cells, Cultured

1992
Initiating activity of 1,1,2,2-tetrachloroethane in two-stage BALB/c 3T3 cell transformation.
    Cancer letters, 1992, Jun-15, Volume: 64, Issue:2

    Topics: 3T3 Cells; Animals; Cell Division; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Ethane; Hydrocarbons, Chlorinated; Liver Extracts; Mice; Mice, Inbred BALB C; Sister Chromatid Exchange; Tetradecanoylphorbol Acetate

1992
Increased intracellular calcium is associated with progression of HPV-18 immortalized human keratinocytes to tumorigenicity.
    Cell calcium, 1991, Volume: 12, Issue:5

    Topics: Calcium; Cell Differentiation; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Flow Cytometry; Humans; Indoles; Keratinocytes; Papillomaviridae; Spectrometry, Fluorescence; Tetradecanoylphorbol Acetate

1991
The tumor promoter 12-O-tetradecanoylphorbol-13-acetate and the ras oncogene modulate expression and phosphorylation of gap junction proteins.
    Molecular and cellular biology, 1991, Volume: 11, Issue:10

    Topics: Animals; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Connexins; Fluorescent Antibody Technique; Gene Expression Regulation; Genes, ras; Harvey murine sarcoma virus; Keratinocytes; Membrane Proteins; Mice; Moloney murine leukemia virus; Phosphorylation; Tetradecanoylphorbol Acetate

1991
In vitro transformation of rat esophageal epithelial cells by fusarin C.
    Science in China. Series B, Chemistry, life sciences & earth sciences, 1991, Volume: 34, Issue:12

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Epithelial Cells; Esophageal Neoplasms; Esophagus; Gene Expression Regulation, Neoplastic; Genes, myc; Mice; Mice, Nude; Mutagens; Oncogene Proteins v-erbB; Oncogenes; Polyenes; Rats; Rats, Inbred Strains; Retroviridae Proteins, Oncogenic; Tetradecanoylphorbol Acetate

1991
Lack of effect of colony-stimulating factors, interleukins, interferons, and tumor necrosis factor on the growth and differentiation of cultured Reed-Sternberg cells. Comparison with effects of phorbol ester and retinoic acid.
    The American journal of pathology, 1990, Volume: 136, Issue:1

    Topics: Aged; Biological Factors; Cell Line; Cell Transformation, Neoplastic; Colony-Stimulating Factors; Cytokines; Hodgkin Disease; Humans; Interferons; Interleukins; Lymphoma; Male; Phorbol Esters; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Necrosis Factor-alpha

1990
Oncogene alterations in in vitro transformed rat tracheal epithelial cells.
    Mutation research, 1990, Volume: 243, Issue:4

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Blotting, Northern; Cell Line; Cell Transformation, Neoplastic; DNA; Epithelium; Gene Amplification; Gene Rearrangement; Genes, ras; Male; Nucleic Acid Hybridization; Oncogene Protein p21(ras); Oncogenes; Polymorphism, Restriction Fragment Length; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myc; Rats; RNA; Tetradecanoylphorbol Acetate; Trachea; Transfection

1990
Differential phosphorylation of myelin-associated glycoprotein isoforms in cell culture.
    Journal of neurochemistry, 1990, Volume: 55, Issue:4

    Topics: Animals; Bucladesine; Cell Line; Cell Transformation, Neoplastic; Cyclic AMP; Epidermal Growth Factor; Insulin; Insulin-Like Growth Factor I; Mice; Myelin Proteins; Myelin-Associated Glycoprotein; Phosphorylation; Tetradecanoylphorbol Acetate; Transfection

1990
Induction of monocytic differentiation by tumor necrosis factor in phorbol ester-resistant KG-1a cells.
    Cancer communications, 1990, Volume: 2, Issue:10

    Topics: Blotting, Northern; Cell Adhesion; Cell Adhesion Molecules; Cell Transformation, Neoplastic; Flow Cytometry; Gene Expression Regulation; Humans; In Vitro Techniques; Leukemia, Myeloid, Acute; Macrophage Colony-Stimulating Factor; Monocytes; Phospholipases A; Phospholipases A2; RNA; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

1990
Effects of antineoplastic phospholipids on parameters of cell differentiation in U937 cells.
    Journal of cancer research and clinical oncology, 1990, Volume: 116, Issue:5

    Topics: Antigens, Surface; Antineoplastic Agents; Blotting, Northern; Cell Transformation, Neoplastic; DNA Probes; Fatty Alcohols; Gene Expression Regulation, Neoplastic; Histones; Leukemia, Promyelocytic, Acute; Lysophosphatidylcholines; Phorbol Esters; Phospholipid Ethers; Phospholipids; Phosphorylcholine; RNA; RNA, Messenger; Tetradecanoylphorbol Acetate

1990
Expression of normal and cystic fibrosis phenotypes by continuous airway epithelial cell lines.
    The American journal of physiology, 1990, Volume: 259, Issue:6 Pt 1

    Topics: Antigens, Polyomavirus Transforming; Base Sequence; Biomarkers; Blood Proteins; Bradykinin; Calcimycin; Calgranulin A; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Chloride Channels; Chlorides; Colforsin; Cystic Fibrosis; Epithelial Cells; Epithelium; Genotype; Humans; Ion Channels; Keratins; Membrane Potentials; Membrane Proteins; Molecular Sequence Data; Nasal Mucosa; Oligonucleotide Probes; Phenotype; Polymerase Chain Reaction; Reference Values; Retroviridae; Simian virus 40; Tetradecanoylphorbol Acetate; Theophylline

1990
Constitutively activated neu oncoprotein tyrosine kinase interferes with growth factor-induced signals for gene activation.
    Journal of cellular biochemistry, 1991, Volume: 45, Issue:1

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; ErbB Receptors; Gene Expression; Genes, ras; Humans; Phosphotyrosine; Poly A; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogenes; Receptor, ErbB-2; RNA; RNA, Messenger; Tetradecanoylphorbol Acetate; Transfection; Tyrosine

1991
TGF-beta 1 and skin carcinogenesis: antiproliferative effect in vitro and TGF-beta 1 mRNA expression during epidermal hyperproliferation and multistage tumorigenesis.
    Molecular carcinogenesis, 1991, Volume: 4, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Animals, Newborn; Blotting, Northern; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; DNA; DNA Replication; DNA, Neoplasm; Female; Gene Expression; Keratinocytes; Mice; Mice, Inbred Strains; Phorbol Esters; RNA; RNA, Messenger; RNA, Neoplasm; Skin; Skin Neoplasms; Skin Physiological Phenomena; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta

1991
Induction of glutathione content in murine melanocytes after transformation with c-H-ras oncogene.
    Carcinogenesis, 1991, Volume: 12, Issue:7

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Genes, ras; Glutathione; Glutathione Transferase; Melanocytes; Mice; RNA; Tetradecanoylphorbol Acetate; Transfection

1991
Dissociation of platelet-derived growth factor (PDGF) receptor autophosphorylation from other PDGF-mediated second messenger events.
    The Journal of biological chemistry, 1991, Jul-25, Volume: 266, Issue:21

    Topics: 1-Phosphatidylinositol 4-Kinase; Animals; Calcium; Cell Division; Cell Line; Cell Transformation, Neoplastic; Chemokine CCL2; Chemotactic Factors; Cyclic AMP; DNA; Gene Expression; Genes, ras; GTP-Binding Proteins; Mice; Phosphorylation; Phosphotransferases; Phosphotyrosine; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-myc; rap GTP-Binding Proteins; Receptors, Cell Surface; Receptors, Platelet-Derived Growth Factor; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection; Type C Phospholipases; Tyrosine

1991
Clinical significance of CD7-positive stem cell leukemia. A distinct subtype of mixed lineage leukemia.
    Cancer, 1991, Nov-15, Volume: 68, Issue:10

    Topics: Acute Disease; Adolescent; Antigens, CD; Antigens, CD7; Antigens, Differentiation, T-Lymphocyte; Cell Transformation, Neoplastic; Child; Child, Preschool; DNA, Neoplasm; Female; Gene Rearrangement; Genotype; Humans; Immunophenotyping; Infant; Karyotyping; Leukemia; Male; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Transcription, Genetic

1991
Correlation of c-fos/c-jun expression with histiocytic differentiation in Hodgkin's Reed-Sternberg cells. Examination in HDLM-1 subclones with spontaneous differentiation.
    The American journal of pathology, 1992, Volume: 140, Issue:1

    Topics: Adult; Aged; Base Sequence; Cell Transformation, Neoplastic; DNA, Neoplasm; Fluorescent Antibody Technique; Histiocytes; Hodgkin Disease; Humans; Male; Phenotype; Pleural Effusion; Proto-Oncogene Mas; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Reed-Sternberg Cells; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1992
Highly purified human alpha-thrombin promotes morphological transformation of BALB/c 3T3 cells.
    Carcinogenesis, 1992, Volume: 13, Issue:1

    Topics: 3T3 Cells; Animals; Cell Transformation, Neoplastic; Epidermal Growth Factor; Mice; Tetradecanoylphorbol Acetate; Thrombin

1992
Transcriptional activity of rel family proteins.
    Oncogene, 1992, Volume: 7, Issue:1

    Topics: Base Sequence; Cell Transformation, Neoplastic; Chloramphenicol O-Acetyltransferase; Enzyme Activation; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Viral; HeLa Cells; HIV Long Terminal Repeat; Humans; Molecular Sequence Data; Neurofibromin 1; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-rel; Tetradecanoylphorbol Acetate; Transfection

1992
Synergistic inhibition of phorbol ester-induced transformation of JB6 cells by transforming growth factor-beta and retinoic acid.
    Cancer research, 1991, Feb-15, Volume: 51, Issue:4

    Topics: Animals; Cell Division; Cell Line; Cell Transformation, Neoplastic; Colony-Forming Units Assay; Dose-Response Relationship, Drug; Drug Synergism; Mice; Mice, Inbred BALB C; Receptors, Cell Surface; Receptors, Transforming Growth Factor beta; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta; Tretinoin

1991
Tumor-promoting activity of Epstein-Barr-virus-inducing factor transforming growth factor type beta (EIF/TGF-beta) is due to the induction of irreversible transformation.
    International journal of cancer, 1991, Apr-01, Volume: 47, Issue:6

    Topics: Animals; Blood Platelets; Cell Line; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Herpesvirus 4, Human; Humans; Mice; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta

1991
Inhibition of chemically induced neoplastic transformation in vitro by saturated fatty acids.
    Pathobiology : journal of immunopathology, molecular and cellular biology, 1991, Volume: 59, Issue:2

    Topics: Animals; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Dose-Response Relationship, Drug; Fatty Acids; In Vitro Techniques; Methylcholanthrene; Oleic Acid; Oleic Acids; Rats; Tetradecanoylphorbol Acetate

1991
Differential genomic susceptibility in malignancy correlates with changes in ATATAT DNA-binding proteins.
    Biochemical and biophysical research communications, 1991, Aug-15, Volume: 178, Issue:3

    Topics: Animals; Base Sequence; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Cholera Toxin; DNA-Binding Proteins; Embryo, Mammalian; Ethers, Cyclic; Genetic Predisposition to Disease; Melanocytes; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Nuclear Proteins; Okadaic Acid; Substrate Specificity; Tetradecanoylphorbol Acetate

1991
Elevation of glucose transporter, c-myc, and transin RNA levels by Ha-rasT24 is independent of its effect on the cell cycle.
    Molecular carcinogenesis, 1991, Volume: 4, Issue:4

    Topics: Animals; Cell Cycle; Cell Line; Cell Transformation, Neoplastic; DNA Replication; Epidermal Growth Factor; Fibroblasts; G1 Phase; Gene Expression; Genes, myc; Genes, ras; Kinetics; Matrix Metalloproteinase 3; Metalloendopeptidases; Monosaccharide Transport Proteins; Neoplasm Proteins; Rats; RNA, Messenger; S Phase; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection

1991
Failure of wild-type or a mutant form of protein kinase C-alpha to transform fibroblasts.
    Nature, 1991, Sep-05, Volume: 353, Issue:6339

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; DNA; Fibroblasts; Fibrosarcoma; Gene Expression; Mice; Mice, Inbred BALB C; Mice, Nude; Mutation; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Transfection

1991
Differential regulation of the p72-74 RAF-1 kinase in 3T3 fibroblasts expressing ras or src oncogenes.
    Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1991, Volume: 2, Issue:5

    Topics: Animals; Cell Line; Cell Membrane; Cell Transformation, Neoplastic; Genes, src; In Vitro Techniques; Mice; Molecular Weight; Oncogene Protein p21(ras); Oncogene Protein pp60(v-src); Phosphoproteins; Phosphorylation; Platelet-Derived Growth Factor; Protein Kinase C; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Tetradecanoylphorbol Acetate

1991
[Genetics of cancerogenesis. Experimental model in mice].
    Pathologie-biologie, 1991, Volume: 39, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Drug Resistance; Incidence; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Phenotype; Tetradecanoylphorbol Acetate

1991
Human Harvey-ras is biochemically different from Kirsten- or N-ras.
    Oncogene, 1991, Volume: 6, Issue:5

    Topics: Animals; Blotting, Northern; Caenorhabditis elegans Proteins; Carrier Proteins; Cell Line; Cell Transformation, Neoplastic; Gene Expression; Genes, ras; Humans; Mice; Oncogenes; Protein Kinase C; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogenes; Receptors, Drug; RNA, Messenger; Tetradecanoylphorbol Acetate; Transfection

1991
Characterization of phospholipase A2 in monocytic cell lines. Functional and biochemical aspects of membrane association.
    The Biochemical journal, 1991, Jun-15, Volume: 276 ( Pt 3)

    Topics: Arachidonic Acid; Arachidonic Acids; Calcium; Cell Line; Cell Membrane; Cell Transformation, Neoplastic; Cytosol; Edetic Acid; Enzyme Activation; Humans; Leukemia, Myeloid; Magnesium; Membrane Proteins; Phospholipases A; Phospholipases A2; Substrate Specificity; Tetradecanoylphorbol Acetate

1991
Activation of the rasHa gene in urethane-initiated papillomas induced by protocols with high and low frequencies of malignant conversion.
    Cancer communications, 1991, Volume: 3, Issue:9

    Topics: 3T3 Cells; Animals; Blotting, Southern; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; DNA, Neoplasm; Drug Interactions; Female; Gene Expression Regulation, Neoplastic; Genes, ras; Male; Mice; Mice, Nude; Neoplasm Transplantation; Papilloma; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured; Urethane

1991
Active oxygen transforms murine myeloid progenitor cells in vitro.
    International journal of cancer, 1991, Nov-11, Volume: 49, Issue:5

    Topics: Animals; Cell Count; Cell Division; Cell Line; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Granulocytes; Hematopoietic Stem Cells; Hot Temperature; Hydrogen Peroxide; Interleukin-3; Male; Mice; Mice, Inbred DBA; Neoplasm Transplantation; Oxygen; Peroxides; Sodium Fluoride; tert-Butylhydroperoxide; Tetradecanoylphorbol Acetate; Vitamin K

1991
Transformation of mouse skin endothelial cells in vivo by direct application of plasmid DNA encoding the human T24 H-ras oncogene.
    Oncogene, 1991, Volume: 6, Issue:11

    Topics: Animals; Base Sequence; Blotting, Southern; Cell Transformation, Neoplastic; Cloning, Molecular; Electrophoresis, Polyacrylamide Gel; Genes, ras; Humans; Mice; Mice, Inbred Strains; Molecular Sequence Data; Neoplasms, Experimental; Plasmids; Polymerase Chain Reaction; Precipitin Tests; Skin Neoplasms; Tetradecanoylphorbol Acetate

1991
Hepatic peroxisome proliferators induce morphologic transformation of Syrian hamster embryo cells, but not peroxisomal beta oxidation.
    Progress in clinical and biological research, 1991, Volume: 369

    Topics: 2,4-Dichlorophenoxyacetic Acid; 2,4,5-Trichlorophenoxyacetic Acid; Animals; Cell Transformation, Neoplastic; Cells, Cultured; Clofibrate; Cricetinae; Diethylhexyl Phthalate; Digitonin; Embryo, Mammalian; Fatty Alcohols; Hypolipidemic Agents; Liver; Mesocricetus; Microbodies; Nicotinic Acids; Rats; Tetradecanoylphorbol Acetate

1991
Elevation of AP1 activity during F9 cell differentiation is due to increased c-jun transcription.
    The New biologist, 1990, Volume: 2, Issue:4

    Topics: Base Sequence; Cell Differentiation; Cell Transformation, Neoplastic; Colforsin; Cyclic AMP; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; Genetic Markers; Humans; Molecular Sequence Data; Multigene Family; Proto-Oncogene Proteins c-jun; RNA, Messenger; Stem Cells; Tetradecanoylphorbol Acetate; Transcription Factors; Transcription, Genetic; Tretinoin; Tumor Cells, Cultured

1990
Downregulation of the early genomic growth factor response in neu oncogene-transformed cells.
    Oncogene, 1990, Volume: 5, Issue:6

    Topics: Animals; Cell Line, Transformed; Cell Transformation, Neoplastic; Chimera; Down-Regulation; ErbB Receptors; Gene Expression; Growth Substances; Immunohistochemistry; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); Receptor, ErbB-2; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection

1990
Intermolecular association of the p185neu protein and EGF receptor modulates EGF receptor function.
    Cell, 1990, Jun-29, Volume: 61, Issue:7

    Topics: Animals; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cross-Linking Reagents; DNA Replication; Down-Regulation; Epidermal Growth Factor; ErbB Receptors; Fibroblasts; Gene Expression; Kinetics; Macromolecular Substances; Mice; Molecular Weight; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogenes; Receptor, ErbB-2; Tetradecanoylphorbol Acetate; Thymidine

1990
Effects of quercetin, a plant flavonol, on the two-stage transformation in vitro.
    Teratogenesis, carcinogenesis, and mutagenesis, 1990, Volume: 10, Issue:4

    Topics: Animals; Antineoplastic Agents; Cell Transformation, Neoplastic; Clone Cells; Dose-Response Relationship, Drug; Mice; Mice, Inbred BALB C; Quercetin; Tetradecanoylphorbol Acetate

1990
Tumor-promoting phorbol ester and activated Ha-ras synergistically reduce the interleukin 3 requirement in a mast cell line.
    Cancer research, 1991, Jan-15, Volume: 51, Issue:2

    Topics: Animals; Blotting, Northern; Cell Division; Cell Line; Cell Transformation, Neoplastic; Genes, ras; Genetic Vectors; Interleukin-3; Mast Cells; Mice; Phorbol 12,13-Dibutyrate; Protein Kinase C; Restriction Mapping; Tetradecanoylphorbol Acetate; Transfection

1991
Relationship of acivicin-induced monocytoid differentiation of human myeloid leukemia cells to acivicin-induced modulation of growth factor, cytokine, and protooncogene mRNA expression.
    Cancer research, 1991, Feb-15, Volume: 51, Issue:4

    Topics: Antibiotics, Antineoplastic; Cell Differentiation; Cell Transformation, Neoplastic; Cytokines; Gene Expression Regulation, Neoplastic; Genes, myc; Granulocyte-Macrophage Colony-Stimulating Factor; Heat-Shock Proteins; Humans; Interleukin-1; Interleukin-3; Interleukin-6; Isoxazoles; Leukemia, Myeloid; Monocytes; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myb; Proto-Oncogenes; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Necrosis Factor-alpha

1991
Long-chain (sphingoid) bases inhibit multistage carcinogenesis in mouse C3H/10T1/2 cells treated with radiation and phorbol 12-myristate 13-acetate.
    Proceedings of the National Academy of Sciences of the United States of America, 1991, Mar-01, Volume: 88, Issue:5

    Topics: Animals; Biological Transport; Cell Line; Cell Transformation, Neoplastic; Gamma Rays; Kinetics; Mice; Mice, Inbred C3H; Protein Kinase C; Sphingosine; Tetradecanoylphorbol Acetate

1991
Suppression of phorbol ester-enhanced radiation-induced malignancy in vitro by protease inhibitors is independent of protein kinase C.
    Biochemical and biophysical research communications, 1991, Apr-15, Volume: 176, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cell Line; Cell Membrane; Cell Transformation, Neoplastic; Cytosol; DNA Replication; Isoquinolines; Kinetics; Mice; Mice, Inbred C3H; Piperazines; Protease Inhibitors; Protein Kinase C; Tetradecanoylphorbol Acetate; Thymidine; Time Factors; Tosylphenylalanyl Chloromethyl Ketone; X-Rays

1991
Neoplastic transformation of C3H/10T1/2 cells following exposure to 120-Hz modulated 2.45-GHz microwaves and phorbol ester tumor promoter.
    Radiation research, 1991, Volume: 126, Issue:1

    Topics: Animals; Cell Transformation, Neoplastic; Dose-Response Relationship, Radiation; Electromagnetic Fields; Microwaves; Tetradecanoylphorbol Acetate

1991
Phorbol ester and bryostatin differentially regulate the hydrolysis of phosphatidylethanolamine in Ha-ras- and raf-oncogene-transformed NIH 3T3 cells.
    The Biochemical journal, 1991, Jun-01, Volume: 276 ( Pt 2)

    Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Bryostatins; Cell Line; Cell Transformation, Neoplastic; Genes, ras; Guanosine 5'-O-(3-Thiotriphosphate); Hydrolysis; Kinetics; Lactones; Macrolides; Mice; Mice, Inbred Strains; Oncogene Proteins v-raf; Oncogenes; Phosphatidylethanolamines; Phospholipase D; Protein Kinase C; Protein-Tyrosine Kinases; Retroviridae Proteins, Oncogenic; Rubidium; Tetradecanoylphorbol Acetate

1991
Effect of tretinoin on collagen gel contraction induced by mouse 3T3 fibroblasts.
    Journal of dermatological science, 1991, Volume: 2, Issue:1

    Topics: Animals; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Collagen; Fibroblasts; Gels; Mice; Tetradecanoylphorbol Acetate; Tretinoin

1991
Isolation of a gene sequence induced later by tumor-promoting 12-O-tetradecanoylphorbol-13-acetate in mouse osteoblastic cells (MC3T3-E1) and expressed constitutively in ras-transformed cells.
    Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1990, Volume: 1, Issue:11

    Topics: Amino Acid Sequence; Animals; Base Sequence; Blotting, Northern; Cell Line; Cell Transformation, Neoplastic; Cycloheximide; DNA; Gene Expression; Genes; Genes, ras; Mice; Molecular Sequence Data; Osteoblasts; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Tissue Distribution

1990
Elevated expression of proto-oncogenes during interleukin-5-induced growth and differentiation of murine B lineage cells.
    Microbiology and immunology, 1990, Volume: 34, Issue:11

    Topics: Animals; Cell Transformation, Neoplastic; Chronic Disease; Female; Gene Expression Regulation; Immunoglobulin M; Interleukin-5; Kinetics; Leukemia; Mice; Mice, Inbred Strains; Proto-Oncogene Proteins c-myc; Proto-Oncogenes; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1990
Novel ATP-binding heat-inducible protein of Mr = 37,000 that is sensitive to transformation in BALB/3T3 cells.
    Journal of cellular physiology, 1990, Volume: 143, Issue:3

    Topics: 2,2'-Dipyridyl; Adenosine Triphosphate; Animals; Arsenic; Arsenites; Calcimycin; Carrier Proteins; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Chick Embryo; Electrophoresis, Polyacrylamide Gel; Endoplasmic Reticulum Chaperone BiP; Fibroblasts; Heat-Shock Proteins; Methionine; Mice; Mice, Inbred BALB C; Precipitin Tests; Sepharose; Sulfur Radioisotopes; Tetradecanoylphorbol Acetate; Tunicamycin

1990
A Swiss 3T3 variant cell line resistant to the effects of tumor promoters cannot be transformed by src.
    Molecular and cellular biology, 1990, Volume: 10, Issue:8

    Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Deoxyglucose; DNA Probes; DNA Replication; Drug Resistance; Epidermal Growth Factor; Mice; Oncogene Protein pp60(v-src); Oncogenes; Plasmids; Retroviridae; Tetradecanoylphorbol Acetate; Transfection

1990
Papilloma and carcinoma production in DMBA-initiated, onion oil-promoted mouse skin.
    Nutrition and cancer, 1990, Volume: 14, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Allium; Animals; Carcinoma; Cell Transformation, Neoplastic; Female; Garlic; Mice; Papilloma; Plant Oils; Plants, Medicinal; Skin Neoplasms; Tetradecanoylphorbol Acetate

1990
Evidence that weak promotion of carcinogen-initiated cells prevents their progression to malignancy.
    Carcinogenesis, 1990, Volume: 11, Issue:12

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzoflavones; Benzyl Alcohols; Cell Transformation, Neoplastic; Cortisone; Dose-Response Relationship, Drug; Indoles; Mice; Mice, Inbred BALB C; Papilloma; Precancerous Conditions; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin; Vitamin E

1990
The role of the c-fms oncogene in the regulation of HL-60 cell differentiation.
    Oncogene, 1990, Volume: 5, Issue:6

    Topics: Base Sequence; Calcitriol; Cell Transformation, Neoplastic; Colony-Stimulating Factors; Dimethyl Sulfoxide; Gene Expression; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Substances; Humans; Leukemia, Promyelocytic, Acute; Macrophage Colony-Stimulating Factor; Macrophages; Molecular Sequence Data; Oligonucleotides; Polymerase Chain Reaction; Proto-Oncogene Proteins; Receptor, Macrophage Colony-Stimulating Factor; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured

1990
Inhibition of phorbol ester-induced monocytic differentiation and c-fms gene expression by dexamethasone: potential involvement of arachidonic acid metabolites.
    Blood, 1990, Sep-15, Volume: 76, Issue:6

    Topics: Arachidonic Acids; Cell Transformation, Neoplastic; Dexamethasone; Gene Expression Regulation, Leukemic; Humans; Leukemia; Monocytes; Phenotype; Proto-Oncogene Proteins; Receptor, Macrophage Colony-Stimulating Factor; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1990
Induction of differentiation in v-Ha-ras-transformed MDCK cells by prostaglandin E2 and 8-bromo-cyclic AMP is associated with a decrease in steady-state level of inositol 1,4,5-trisphosphate.
    Molecular and cellular biology, 1990, Volume: 10, Issue:1

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; Cyclic AMP; Diglycerides; Dinoprostone; Dogs; Genes, ras; GTP-Binding Proteins; Guanine Nucleotides; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Isoproterenol; Oncogene Protein p21(ras); Phospholipids; Tetradecanoylphorbol Acetate; Time Factors; Virulence Factors, Bordetella

1990
Transcription of the transforming genes of the oncogenic human papillomavirus-16 is stimulated by tumor promotors through AP1 binding sites.
    Nucleic acids research, 1990, Feb-25, Volume: 18, Issue:4

    Topics: Base Sequence; Cell Line; Cell Transformation, Neoplastic; Chloramphenicol O-Acetyltransferase; DNA-Binding Proteins; Genes, Viral; HeLa Cells; Humans; Molecular Sequence Data; Oligonucleotide Probes; Papillomaviridae; Plasmids; Promoter Regions, Genetic; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-jun; Tetradecanoylphorbol Acetate; Transcription Factors; Transcription, Genetic; Transfection

1990
Adenovirus E1A represses protease gene expression and inhibits metastasis of human tumor cells.
    Oncogene, 1990, Volume: 5, Issue:1

    Topics: Adenovirus Early Proteins; Base Sequence; Cell Transformation, Neoplastic; Chloramphenicol O-Acetyltransferase; DNA-Binding Proteins; Gene Expression; Humans; Metalloendopeptidases; Microbial Collagenase; Molecular Sequence Data; Neoplasm Invasiveness; Neoplasm Metastasis; Oncogene Proteins, Viral; Peptide Hydrolases; Proto-Oncogene Proteins c-jun; Proto-Oncogenes; Tetradecanoylphorbol Acetate; Transcription Factors; Transcription, Genetic; Transfection

1990
Persistent induction of cyclooxygenase in p60v-src-transformed 3T3 fibroblasts.
    Proceedings of the National Academy of Sciences of the United States of America, 1990, Volume: 87, Issue:9

    Topics: Animals; Avian Sarcoma Viruses; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Dexamethasone; Enzyme Induction; Kinetics; Methionine; Mice; Mutation; Oncogene Protein pp60(v-src); Platelet-Derived Growth Factor; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Protein-Tyrosine Kinases; Temperature; Tetradecanoylphorbol Acetate

1990
Increased erythroid potentiating activity/tissue inhibitor of metalloproteinases and jun/fos transcription factor complex characterize tumor promoter-induced megakaryoblastic differentiation of K562 leukemia cells.
    Blood, 1990, May-15, Volume: 75, Issue:10

    Topics: Cell Line; Cell Transformation, Neoplastic; DNA-Binding Proteins; Gene Expression; Glycoproteins; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Lymphokines; Microbial Collagenase; Protein Biosynthesis; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; RNA, Messenger; Tetradecanoylphorbol Acetate; Tissue Inhibitor of Metalloproteinases; Transcription Factors

1990
Mononuclear phagocytes and HSV-1 infection: increased permissivity in differentiated U937 cells is mediated by post-transcriptional regulation of viral immediate-early gene expression.
    Journal of leukocyte biology, 1990, Volume: 47, Issue:6

    Topics: Cell Line; Cell Transformation, Neoplastic; Dihydroxycholecalciferols; Gene Expression Regulation, Viral; Genes, Regulator; Genes, Viral; Herpes Simplex; Humans; Leukemia, Myelomonocytic, Acute; Phagocytes; RNA, Viral; Simplexvirus; Tetradecanoylphorbol Acetate; Transcription, Genetic

1990
BK virus early RNA transcripts in stably transformed cells: enhanced levels induced by dibutyryl cyclic AMP, forskolin and 12-O-tetradecanoylphorbol-13-acetate treatment.
    The Journal of general virology, 1990, Volume: 71 ( Pt 7)

    Topics: Animals; Base Sequence; BK Virus; Blotting, Southern; Bucladesine; Cell Line; Cell Transformation, Neoplastic; Colforsin; Cricetinae; DNA, Single-Stranded; DNA, Viral; Genes, Viral; Molecular Sequence Data; Nucleic Acid Hybridization; Oligonucleotide Probes; Polymerase Chain Reaction; Polyomavirus; RNA, Viral; Tetradecanoylphorbol Acetate; Transcription, Genetic

1990
Cultured Reed-Sternberg cells HDLM-1 and KM-H2 can be induced to become histiocytelike cells. H-RS cells are not derived from lymphocytes.
    The American journal of pathology, 1990, Volume: 137, Issue:2

    Topics: Adult; Antigens, Differentiation; Antigens, Neoplasm; Arachidonic Acids; Biological Factors; Cell Transformation, Neoplastic; Cytokines; Extracellular Matrix; Gene Rearrangement; Histiocytes; Hodgkin Disease; Humans; Ki-1 Antigen; Lymphocytes; Male; Phagocytosis; Phenotype; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured

1990
Loss of bradykinin receptors and TPA-stimulated Na+ influx in SV40-transformed WI-38 cells.
    The American journal of physiology, 1990, Volume: 259, Issue:4 Pt 1

    Topics: Amiloride; Bradykinin; Cell Division; Cell Line; Cell Transformation, Neoplastic; Growth Substances; Humans; Inositol Phosphates; Kinetics; Receptors, Bradykinin; Receptors, Neurotransmitter; Simian virus 40; Sodium; Tetradecanoylphorbol Acetate

1990
Expression of the chloramphenicol acetyltransferase (CAT) reporter gene by the murine Cyp1a-2 (cytochrome P3(450)) promoter in hepatoma cell cultures.
    Biochemical and biophysical research communications, 1990, Nov-15, Volume: 172, Issue:3

    Topics: Animals; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Chloramphenicol O-Acetyltransferase; Cytochrome P-450 Enzyme System; Gene Expression Regulation, Enzymologic; Mice; Mice, Inbred C57BL; Plasmids; Promoter Regions, Genetic; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1990
Herpes simplex virus type-1-induced stimulation of ribosomal protein S6 phosphorylation is inhibited in neomycin-treated human epidermoid carcinoma 2 cells and in ras-transformed cells.
    European journal of biochemistry, 1990, Nov-26, Volume: 194, Issue:1

    Topics: Animals; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Genes, ras; Herpes Simplex; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Neomycin; Phosphatidylinositols; Phosphorylation; Protein Kinase C; Rats; Ribosomal Protein S6; Ribosomal Proteins; Simplexvirus; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1990
Identification of a serum-inducible messenger RNA (5B10) as the mouse homologue of calcyclin: tissue distribution and expression in metastatic, ras-transformed NIH 3T3 cells.
    Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1990, Volume: 1, Issue:7

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Amino Acid Sequence; Animals; Base Sequence; Calcium-Binding Proteins; Cell Cycle Proteins; Cell Division; Cell Line, Transformed; Cell Transformation, Neoplastic; Cell Transformation, Viral; Chick Embryo; Fibroblasts; Gene Expression Regulation; Mice; Mice, Nude; Molecular Sequence Data; Neoplasm Metastasis; Neoplasm Proteins; Neoplasm Transplantation; Oncogene Protein p21(ras); Organ Specificity; S100 Calcium Binding Protein A6; S100 Proteins; Simian virus 40; Species Specificity; Tetradecanoylphorbol Acetate

1990
Potentiation of oncogenic N-ras-induced neurite outgrowth and ornithine decarboxylase activity by phorbol dibutyrate and protein kinase inhibitor H-8.
    Journal of cellular physiology, 1990, Volume: 143, Issue:1

    Topics: Animals; Cell Differentiation; Cell Transformation, Neoplastic; Colforsin; Dexamethasone; Epidermal Growth Factor; Isoquinolines; Nerve Growth Factors; Neurons; Oncogene Protein p21(ras); Ornithine Decarboxylase; Phorbol 12,13-Dibutyrate; Protein Kinase C; Protein Kinase Inhibitors; Rats; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured

1990
Establishment of a highly reproducible transformation assay of a ras-transfected BALB 3T3 clone by treatment with promoters.
    Basic life sciences, 1990, Volume: 52

    Topics: Animals; Carcinogenicity Tests; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Clone Cells; Cocarcinogenesis; Fibroblasts; Mice; Mice, Inbred BALB C; Oncogene Protein p21(ras); Tetradecanoylphorbol Acetate

1990
A RAS oncogene imparts growth factor independence to myeloid cells that abnormally regulate protein kinase C: a nonautocrine transformation pathway.
    Experimental hematology, 1990, Volume: 18, Issue:5

    Topics: Cell Division; Cell Line; Cell Transformation, Neoplastic; Down-Regulation; Drug Resistance; Enzyme Activation; Gene Expression; Genes, ras; Genetic Vectors; Granulocytes; Humans; Interleukin-3; Mutation; Neomycin; Protein Kinase C; Tetradecanoylphorbol Acetate; Transfection

1990
Analysis of nuclear sugar-binding components in undifferentiated and in vitro differentiated human promyelocytic leukemia cells (HL60).
    Experimental cell research, 1990, Volume: 190, Issue:2

    Topics: Carrier Proteins; Cell Differentiation; Cell Nucleus; Cell Transformation, Neoplastic; Dimethyl Sulfoxide; DNA; Fluorescein; Fluoresceins; Humans; Lectins; Leukemia, Promyelocytic, Acute; Microscopy, Fluorescence; Nuclear Proteins; Phenotype; Receptors, Cell Surface; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1990
Initiating activity of 3-tert-butyl-4-hydroxyanisole (3-BHA) and its metabolites in two-stage transformation of BALB/3T3 cells.
    Carcinogenesis, 1990, Volume: 11, Issue:11

    Topics: Animals; Benzoquinones; Butylated Hydroxyanisole; Carcinogenicity Tests; Cell Transformation, Neoplastic; Cells, Cultured; Dimethyl Sulfoxide; Mice; Tetradecanoylphorbol Acetate

1990
Myeloid leukemia differentiation by phorbol ester and retinoic acid: a practical approach.
    Journal of clinical laboratory analysis, 1990, Volume: 4, Issue:5

    Topics: Cell Transformation, Neoplastic; Diagnosis, Differential; Humans; Leukemia, Erythroblastic, Acute; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid; Leukemia, Promyelocytic, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tetradecanoylphorbol Acetate; Tretinoin

1990
Studies of the rad-equivalence of ethylene oxide in the presence and absence of 12-O-tetradecanoylphorbol-13-acetate (TPA) in C3H/10T1/2 cells.
    Toxicology letters, 1990, Volume: 53, Issue:3

    Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Culture Media; Ethylene Oxide; Fibroblasts; Gamma Rays; Linear Models; Mice; Radiation Dosage; Tetradecanoylphorbol Acetate; Time Factors

1990
v-Ha-ras transgene abrogates the initiation step in mouse skin tumorigenesis: effects of phorbol esters and retinoic acid.
    Proceedings of the National Academy of Sciences of the United States of America, 1990, Volume: 87, Issue:23

    Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Genes, ras; Keratinocytes; Mice; Mice, Inbred Strains; Mice, Transgenic; Plasmids; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin

1990
Characterization of epidermal growth factor receptor induction by retinoic acid in a chemically transformed rat liver cell line.
    Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1990, Volume: 1, Issue:9

    Topics: Animals; Blotting, Northern; Cell Line; Cell Transformation, Neoplastic; Cycloheximide; Epidermal Growth Factor; Epithelial Cells; ErbB Receptors; Gene Expression; In Vitro Techniques; Methylnitronitrosoguanidine; Precipitin Tests; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Tretinoin

1990
Regulation of the relative abundances of c-myc mRNAs in human promyelocytic HL60 cells.
    Differentiation; research in biological diversity, 1990, Volume: 45, Issue:1

    Topics: Cell Transformation, Neoplastic; Dimethyl Sulfoxide; Gene Expression Regulation, Neoplastic; Humans; Leukemia, Promyelocytic, Acute; Promoter Regions, Genetic; Proto-Oncogene Proteins c-myc; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured

1990
Induction of differentiation of the human histiocytic lymphoma cell line U937 in the absence of vimentin expression.
    Differentiation; research in biological diversity, 1990, Volume: 45, Issue:1

    Topics: Calcitriol; Cell Transformation, Neoplastic; Fluorescent Antibody Technique; Gene Expression Regulation, Neoplastic; Humans; Immunoblotting; Intermediate Filaments; Lymphoma, Large B-Cell, Diffuse; Phagocytosis; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured; Vimentin

1990
In vitro establishment and characterization of a human megakaryoblastic cell line.
    Blood, 1990, Mar-15, Volume: 75, Issue:6

    Topics: Blotting, Northern; Bone Marrow; Bone Marrow Cells; Cell Differentiation; Cell Line; Cell Nucleus; Cell Transformation, Neoplastic; Humans; Karyotyping; Leukemia, Megakaryoblastic, Acute; Megakaryocytes; Microscopy, Electron; Tetradecanoylphorbol Acetate

1990
Inhibition of 12-O-tetradecanoylphorbol-13-acetate-enhanced transformation in vitro by inhibitors of phospholipid metabolism.
    Toxicology letters, 1990, Volume: 51, Issue:1

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Cocarcinogenesis; Dose-Response Relationship, Drug; Drug Antagonism; Hydrocortisone; Methylcholanthrene; Mice; Mice, Inbred BALB C; Phospholipids; Tetradecanoylphorbol Acetate

1990
Effects of activators and inhibitors of protein kinase C on two-stage transformation in BALB/3T3 cells.
    Toxicology letters, 1990, Volume: 51, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Cell Line; Cell Transformation, Neoplastic; Cocarcinogenesis; Diglycerides; Drug Antagonism; Enzyme Activation; Glycerides; Isoquinolines; Methylcholanthrene; Mice; Palmitoylcarnitine; Piperazines; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate

1990
Cellular F-actin levels as a marker for cellular transformation: relationship to cell division and differentiation.
    Cancer research, 1990, Apr-15, Volume: 50, Issue:8

    Topics: Actins; Biomarkers, Tumor; Cell Differentiation; Cell Division; Cell Line; Cell Transformation, Neoplastic; Dimethyl Sulfoxide; Flow Cytometry; Humans; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured

1990
The non-phorbol ester tumor promoter okadaic acid does not promote morphological transformation or inhibit junctional communication in hamster embryo cells.
    Biochemical and biophysical research communications, 1990, Mar-30, Volume: 167, Issue:3

    Topics: Animals; Carcinogens; Cell Communication; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Embryo, Mammalian; Ethers, Cyclic; Intercellular Junctions; Mesocricetus; Okadaic Acid; Tetradecanoylphorbol Acetate

1990
Study of various transforming effects of the anabolic agents trenbolone and testosterone on Syrian hamster embryo cells.
    Carcinogenesis, 1990, Volume: 11, Issue:4

    Topics: Animals; Benzo(a)pyrene; Cell Line; Cell Line, Transformed; Cell Transformation, Neoplastic; Cricetinae; Estrenes; Testosterone; Tetradecanoylphorbol Acetate; Trenbolone Acetate

1990
Effect of 12-O-tetradecanoylphorbol-13-acetate on colony formation and intercellular communication in a coculture system of JB6 clones.
    Cancer research, 1990, Sep-01, Volume: 50, Issue:17

    Topics: Animals; Cell Aggregation; Cell Communication; Cell Division; Cell Line; Cell Transformation, Neoplastic; Clone Cells; Epidermis; Fluorescent Dyes; Isoquinolines; Kinetics; Mice; Tetradecanoylphorbol Acetate

1990
A host-mediated in vivo/in vitro assay with peritoneal murine macrophages for the detection of carcinogenic chemicals.
    Journal of cancer research and clinical oncology, 1990, Volume: 116, Issue:4

    Topics: 1-Naphthylamine; Animals; Carcinogenicity Tests; Carcinogens; Cell Transformation, Neoplastic; Drug Evaluation, Preclinical; Macrophages; Male; Mice; Peritoneal Cavity; Phenytoin; Tetradecanoylphorbol Acetate

1990
ras oncogene activation of a VL30 transcriptional element is linked to transformation.
    Molecular and cellular biology, 1990, Volume: 10, Issue:1

    Topics: Animals; Base Sequence; Cell Transformation, Neoplastic; DNA Mutational Analysis; Gene Expression Regulation; Genes, ras; Mice; Molecular Sequence Data; Nuclear Proteins; Oncogene Protein p21(ras); Regulatory Sequences, Nucleic Acid; Repetitive Sequences, Nucleic Acid; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factors

1990
Inhibition of radiation-induced transformation of C3H/10T1/2 cells by specific protease substrates.
    Carcinogenesis, 1990, Volume: 11, Issue:2

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Mice; Oligopeptides; Peptide Hydrolases; Protease Inhibitors; Tetradecanoylphorbol Acetate

1990
Induction of the expression of differentiation-related antigens on human colon carcinoma cells by stimulating protein kinase C.
    Archives of surgery (Chicago, Ill. : 1960), 1990, Volume: 125, Issue:3

    Topics: Antibodies, Monoclonal; Antigens, Differentiation; Antigens, Neoplasm; Autoradiography; Carcinoma; Cell Line; Cell Transformation, Neoplastic; Colonic Neoplasms; Flow Cytometry; Fluorescent Antibody Technique; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Immunoenzyme Techniques; Microscopy, Electron; Protein Kinase C; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1990
Responses of human cervical keratinocytes in vitro to tumour promoters and diethylstilboestrol.
    Carcinogenesis, 1985, Volume: 6, Issue:7

    Topics: Carcinogens; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Cervix Uteri; Clone Cells; Diethylstilbestrol; Diterpenes; Female; Humans; Keratins; Kinetics; Phorbols; Terpenes; Tetradecanoylphorbol Acetate

1985
Class II histocompatibility antigen expression in human melanocytes transformed by Harvey murine sarcoma virus (Ha-MSV) and Kirsten MSV retroviruses.
    The Journal of experimental medicine, 1986, Nov-01, Volume: 164, Issue:5

    Topics: Cell Division; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Harvey murine sarcoma virus; Histocompatibility Antigens Class II; Humans; Interferon-gamma; Kirsten murine sarcoma virus; Melanocytes; Melanoma; Oncogenes; RNA; Tetradecanoylphorbol Acetate

1986
Multistage transformation of cultured rat urothelium: the effects of N-methyl-N-nitrosourea, sodium saccharin, sodium cyclamate and 12-O-tetradecanoylphorbol-13-acetate.
    Carcinogenesis, 1986, Volume: 7, Issue:12

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Cocarcinogenesis; Cyclamates; Epithelium; Female; Hyperplasia; Methylnitrosourea; Phenotype; Rats; Rats, Inbred F344; Saccharin; Tetradecanoylphorbol Acetate; Urinary Bladder

1986
Degradation and biosynthesis of the glucose transporter protein in chicken embryo fibroblasts transformed by the src oncogene.
    Molecular and cellular biology, 1987, Volume: 7, Issue:6

    Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Chick Embryo; Culture Media; Fibroblasts; Genes; Kinetics; Monosaccharide Transport Proteins; Oncogenes; Phosphorylation; Protein Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins pp60(c-src); Tetradecanoylphorbol Acetate; Vanadates; Vanadium

1987
Phospholipase C mimics the differential effects of phorbol-12-myristate-13-acetate on the colony formation and cornification of cultured normal and transformed human keratinocytes.
    Carcinogenesis, 1987, Volume: 8, Issue:6

    Topics: Cell Transformation, Neoplastic; Cells, Cultured; Epidermal Cells; Epidermis; Humans; Keratins; Kinetics; Skin; Tetradecanoylphorbol Acetate; Type C Phospholipases

1987
Effect of 5-azacytidine on malignant transformation of a mutant derived from the mouse BALB/c 3T3 cell line resistant to transformation by chemical carcinogens.
    Cancer research, 1987, Sep-15, Volume: 47, Issue:18

    Topics: 4-Nitroquinoline-1-oxide; Animals; Azacitidine; Benzo(a)pyrene; Cell Line; Cell Transformation, Neoplastic; DNA; Epidermal Growth Factor; Metallothionein; Methylation; Methylnitronitrosoguanidine; Mice; Mice, Inbred BALB C; Mutation; Proto-Oncogenes; Tetradecanoylphorbol Acetate

1987
Role of second messengers in regulating the growth-associated S6 protein kinase activity.
    Progress in clinical and biological research, 1987, Volume: 249

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Avian Sarcoma Viruses; Bucladesine; Calcimycin; Cell Transformation, Neoplastic; Chick Embryo; Cyclic AMP; Fibroblasts; Inositol Phosphates; Kinetics; Phosphorylation; Protein Kinases; Proto-Oncogenes; Tetradecanoylphorbol Acetate

1987
Transcriptional control of high molecular weight keratin gene expression in multistage mouse skin carcinogenesis.
    Cancer research, 1988, Jun-01, Volume: 48, Issue:11

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Animals, Newborn; Carcinoma; Cell Transformation, Neoplastic; Female; Gene Expression Regulation; Genes; Keratins; Mice; Mice, Inbred Strains; Nucleic Acid Hybridization; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription, Genetic

1988
Carbachol-induced reverse transformation of Chinese hamster ovary cells transfected with and expressing the m5 muscarinic acetylcholine receptor.
    FEBS letters, 1989, Mar-13, Volume: 245, Issue:1-2

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Carbachol; Cell Line; Cell Transformation, Neoplastic; Cholecystokinin; Cricetinae; Cyclic AMP; Dinoprostone; Female; Kinetics; Ovary; Receptors, Muscarinic; Tetradecanoylphorbol Acetate; Transfection

1989
Mitogenic activity of phorbol esters and insulin-like growth factor 1 in chemically transformed mouse fibroblasts BP-A31: independent effects and differential sensitivity to inhibition by 3-isobutyl-1-methyl xanthine.
    Experimental cell research, 1989, Volume: 182, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Blotting, Northern; Cell Division; Cell Transformation, Neoplastic; Colforsin; Cyclic AMP; Cycloheximide; Epidermal Growth Factor; Gene Expression Regulation; Insulin; Insulin-Like Growth Factor I; Mice; Platelet-Derived Growth Factor; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Somatomedins; Suramin; Tetradecanoylphorbol Acetate; Theophylline

1989
Mutation of amino acids in pp60c-src that are phosphorylated by protein kinases C and A.
    Molecular and cellular biology, 1989, Volume: 9, Issue:6

    Topics: Amino Acids; Animals; Cell Transformation, Neoplastic; DNA Mutational Analysis; Gene Expression Regulation; Mice; Mutation; Phosphorylation; Plasmids; Protein Kinase C; Protein Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins pp60(c-src); Serine; Tetradecanoylphorbol Acetate

1989
Germ line c-myc is not down-regulated by loss or exclusion of activating factors in myc-induced macrophage tumors.
    Molecular and cellular biology, 1989, Volume: 9, Issue:8

    Topics: Animals; Base Sequence; Bucladesine; Cell Transformation, Neoplastic; Chromatin; Colony-Stimulating Factors; Deoxyribonuclease I; DNA; Exons; Gene Expression Regulation; Humans; Macrophages; Methylation; Mice; Molecular Sequence Data; Oncogenes; RNA; Sequence Homology, Nucleic Acid; Tetradecanoylphorbol Acetate; Transcription, Genetic

1989
Modulation of ornithine decarboxylase gene transcript levels by differentiation inducers in human promyelocytic leukemia HL60 cells.
    Cell differentiation and development : the official journal of the International Society of Developmental Biologists, 1989, Volume: 28, Issue:1

    Topics: Bucladesine; Calcitriol; Cell Line; Cell Transformation, Neoplastic; Dimethyl Sulfoxide; Gene Expression; Humans; Leukemia, Promyelocytic, Acute; Ornithine Decarboxylase; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myc; RNA; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tretinoin

1989
Malignant conversion of UV radiation and chemically induced mouse skin benign tumors by free-radical-generating compounds.
    Carcinogenesis, 1989, Volume: 10, Issue:10

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Amidines; Animals; Benzoyl Peroxide; Carcinogens; Cell Transformation, Neoplastic; Female; Free Radicals; Mice; Mice, Hairless; Mice, Inbred Strains; Neoplasms, Radiation-Induced; Papilloma; Peroxides; Skin; Skin Diseases; Skin Neoplasms; tert-Butylhydroperoxide; Tetradecanoylphorbol Acetate; Ultraviolet Rays

1989
Reduced induction of c-fos but not of c-myc expressions in a nontumorigenic revertant R1 of Ej-ras-transformed NIH/3T3 cells treated with 12-O-tetradecanoylphorbol-13-acetate (TPA).
    Experimental cell research, 1989, Volume: 184, Issue:2

    Topics: Animals; Cell Line, Transformed; Cell Transformation, Neoplastic; Fibroblasts; Gene Expression Regulation, Neoplastic; Humans; Mice; Phenotype; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-myc; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic

1989
Consistent oncogene methylation changes in epithelial cells chemically transformed in vitro.
    Biochemical and biophysical research communications, 1989, Oct-31, Volume: 164, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Base Sequence; Benzo(a)pyrene; Blotting, Southern; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; DNA; Epithelial Cells; Epithelium; Genes, ras; Male; Methylation; Proto-Oncogenes; Rats; Rats, Inbred F344; Restriction Mapping; Tetradecanoylphorbol Acetate; Trachea

1989
[Inhibitory effect of green tea extract on promotion and related action of TPA].
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 1989, Volume: 11, Issue:4

    Topics: Animals; Antioxidants; Catechin; Cell Transformation, Neoplastic; Edema; Female; Mice; Mice, Inbred BALB C; Ornithine Decarboxylase; Sister Chromatid Exchange; Tea; Tetradecanoylphorbol Acetate

1989
AP1/jun function is differentially induced in promotion-sensitive and resistant JB6 cells.
    Science (New York, N.Y.), 1989, May-05, Volume: 244, Issue:4904

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Chloramphenicol O-Acetyltransferase; Cloning, Molecular; DNA-Binding Proteins; Epidermal Growth Factor; Epidermis; Gene Expression Regulation; Genetic Variation; Kinetics; Mice; Nucleic Acid Hybridization; Plasmids; Promoter Regions, Genetic; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-jun; Simplexvirus; Tetradecanoylphorbol Acetate; Transcription Factors; Transfection

1989
Loss of responsiveness of an AP1-related factor, PEBP1, to 12-O-tetradecanoylphorbol-13-acetate after transformation of NIH 3T3 cells by the Ha-ras oncogene.
    Journal of virology, 1989, Volume: 63, Issue:9

    Topics: Animals; Binding Sites; Cell Transformation, Neoplastic; Chromatography; DNA-Binding Proteins; Enhancer Elements, Genetic; Genes, ras; Mice; Phosphoric Monoester Hydrolases; Phosphorylation; Protein Kinase C; Proto-Oncogene Proteins c-jun; Tetradecanoylphorbol Acetate; Transcription Factors

1989
Enhancement of the invasive ability of a transformed human bronchial epithelial cell line by 12-O-tetradecanoyl-phorbol-13-acetate and diacylglycerol.
    Carcinogenesis, 1989, Volume: 10, Issue:12

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Chemotaxis; Diglycerides; Epithelium; Glycerides; Humans; Lung; Mice; Mice, Nude; Microbial Collagenase; Neoplasm Invasiveness; Neoplasm Transplantation; Rats; Tetradecanoylphorbol Acetate; Trachea; Transplantation, Heterologous

1989
Activation of the cellular Harvey ras gene in mouse skin tumors initiated with urethane.
    Molecular carcinogenesis, 1989, Volume: 2, Issue:1

    Topics: Animals; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cocarcinogenesis; Codon; DNA Probes; Gene Amplification; Genes, ras; Mice; Mutation; Papilloma; Polymorphism, Restriction Fragment Length; Proto-Oncogene Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Stem Cell Assay; Urethane

1989
Multistage-promotion and carcinogenesis studies in rat tracheal epithelial cells in culture.
    Carcinogenesis; a comprehensive survey, 1985, Volume: 8

    Topics: Aneuploidy; Animals; Cell Transformation, Neoplastic; Cells, Cultured; DNA; Keratins; Methylnitronitrosoguanidine; Rats; Rats, Inbred F344; Tetradecanoylphorbol Acetate; Tracheal Neoplasms

1985
Cytoplasmic domains determine signal specificity, cellular routing characteristics and influence ligand binding of epidermal growth factor and insulin receptors.
    The EMBO journal, 1989, Volume: 8, Issue:10

    Topics: Animals; Binding Sites; Cell Division; Cell Line; Cell Membrane; Cell Transformation, Neoplastic; Chimera; Cytoplasm; DNA; ErbB Receptors; Fibroblasts; Gene Expression Regulation; Humans; Ligands; Mice; Phosphorylation; Receptor, Insulin; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection

1989
Detection of distinct transforming genes in X-ray induced tumors.
    Carcinogenesis, 1989, Volume: 10, Issue:12

    Topics: Animals; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cells, Cultured; Cocarcinogenesis; Mice; Mice, Inbred Strains; Neoplasms, Radiation-Induced; Oncogenes; Papilloma; Restriction Mapping; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transfection; X-Rays

1989
Effect of tea on 12-O tetradecanoyl-phorbol-13 acetate (TPA) induced promotion of transformation in JB6 mouse epidermal cells.
    Indian journal of cancer, 1989, Volume: 26, Issue:2

    Topics: Animals; Antioxidants; Cell Line, Transformed; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Mice; Tea; Tetradecanoylphorbol Acetate

1989
Calcium-independent growth of human ovarian carcinoma cells.
    Journal of cellular physiology, 1989, Volume: 141, Issue:3

    Topics: Animals; Calcium; Calmodulin; Carcinoma; Cell Line; Cell Transformation, Neoplastic; Cricetinae; Cricetulus; Culture Media; Dose-Response Relationship, Drug; Female; Humans; Ovarian Neoplasms; Ovary; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1989
Tumor promotion and depletion of protein kinase C in epidermal JB6 cells.
    Biochemical and biophysical research communications, 1989, Dec-29, Volume: 165, Issue:3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Cell Division; Cell Line; Cell Transformation, Neoplastic; Enzyme Activation; Epidermis; Immunoblotting; Isoquinolines; Peptide Fragments; Piperazines; Protein Kinase C; Tetradecanoylphorbol Acetate

1989
Regulation of ornithine decarboxylase gene expression in normal and transformed hamster embryo fibroblasts following stimulation by 12-O-tetradecanoylphorbol-13-acetate.
    Carcinogenesis, 1989, Volume: 10, Issue:1

    Topics: Animals; Blotting, Northern; Blotting, Southern; Cell Transformation, Neoplastic; Cricetinae; Cycloheximide; Dactinomycin; Gene Expression Regulation; Ornithine Decarboxylase; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myc; RNA, Messenger; Tetradecanoylphorbol Acetate

1989
Effects of triiodothyronine and tamoxifen on cell transformation induced by an activated c-Ha-ras oncogene.
    Cancer research, 1989, Feb-15, Volume: 49, Issue:4

    Topics: Animals; Blotting, Southern; Cell Line; Cell Transformation, Neoplastic; Clone Cells; DNA; Genes, ras; Tamoxifen; Tetradecanoylphorbol Acetate; Transfection; Triiodothyronine

1989
Characterization of the human cell line TE671.
    Carcinogenesis, 1989, Volume: 10, Issue:5

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Cerebellar Neoplasms; DNA, Neoplasm; Gene Expression Regulation; Genes, ras; Humans; Karyotyping; Medulloblastoma; Mice; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured

1989
Similar and synergistic inhibition of gap-junctional communication by ras transformation and tumor promoter treatment of mouse primary keratinocytes.
    Oncogene, 1989, Volume: 4, Issue:5

    Topics: Animals; Cell Communication; Cell Differentiation; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Epidermal Cells; Fibroblasts; Genes, ras; Mice; Mice, Inbred BALB C; Tetradecanoylphorbol Acetate

1989
Transformation stimulates glucose transporter gene expression in the absence of protein kinase C.
    Proceedings of the National Academy of Sciences of the United States of America, 1989, Volume: 86, Issue:21

    Topics: Animals; Brain; Cell Line; Cell Transformation, Neoplastic; Gene Expression Regulation; Genes, ras; Humans; Kinetics; Monosaccharide Transport Proteins; Oncogenes; Protein Kinase C; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic

1989
Flat reversion by okadaic acid of raf and ret-II transformants.
    Proceedings of the National Academy of Sciences of the United States of America, 1989, Volume: 86, Issue:24

    Topics: Animals; Blotting, Northern; Blotting, Western; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Ethers, Cyclic; Fibronectins; Fluorescent Antibody Technique; Genes, ras; Ionophores; Kinetics; Mice; Okadaic Acid; Oncogenes; Proto-Oncogenes; Tetradecanoylphorbol Acetate; Transfection

1989
The phospholipid- and calcium-dependent protein kinase as a target in tumor chemotherapy.
    Advances in enzyme regulation, 1989, Volume: 28

    Topics: Animals; Antineoplastic Agents; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Dexamethasone; Genes, ras; Kinetics; Mice; Phosphorylation; Protein Kinase C; Ribosomal Protein S6; Ribosomal Proteins; Tetradecanoylphorbol Acetate; Transfection

1989
2,3,7,8-Tetrachlorodibenzo-p-dioxin enhancement of N-methyl-N'-nitro-N-nitrosoguanidine-induced transformation of rat tracheal epithelial cells in culture.
    Cancer research, 1989, May-15, Volume: 49, Issue:10

    Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Dioxins; Dose-Response Relationship, Drug; Epithelium; Male; Methylnitronitrosoguanidine; Polychlorinated Dibenzodioxins; Rats; Rats, Inbred F344; Tetradecanoylphorbol Acetate; Trachea

1989
Osteopontin, a transformation-associated cell adhesion phosphoprotein, is induced by 12-O-tetradecanoylphorbol 13-acetate in mouse epidermis.
    The Journal of biological chemistry, 1989, Jun-05, Volume: 264, Issue:16

    Topics: Amino Acid Sequence; Animals; Base Sequence; Cell Adhesion; Cell Transformation, Neoplastic; DNA; Epidermis; Female; Mice; Molecular Sequence Data; Osteopontin; Phosphoproteins; Protein Biosynthesis; Protein Processing, Post-Translational; Sequence Homology, Nucleic Acid; Sialoglycoproteins; Tetradecanoylphorbol Acetate

1989
Enhanced jun gene expression is an early genomic response to transforming growth factor beta stimulation.
    Molecular and cellular biology, 1989, Volume: 9, Issue:3

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Gene Expression Regulation; Humans; Proto-Oncogene Mas; Proto-Oncogenes; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription Factors; Transfection; Transforming Growth Factors

1989
[Changes in the morphology of fibroblasts of different degrees of transformation under the action of 12-tetradecanoylphorbol-13-acetate].
    Tsitologiia, 1989, Volume: 31, Issue:3

    Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Embryo, Mammalian; Fibroblasts; Mice; Mice, Inbred BALB C; Mice, Inbred CBA; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1989
Promoter-enhanced neoplastic transformation after gamma-ray exposure at 10 cGy/day.
    Radiation research, 1989, Volume: 119, Issue:2

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Cobalt Radioisotopes; Gamma Rays; Mice; Stimulation, Chemical; Tetradecanoylphorbol Acetate

1989
Continuous-wave ultrasound and neoplastic transformation in vitro.
    Ultrasound in medicine & biology, 1989, Volume: 15, Issue:4

    Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Cocarcinogenesis; Fibroblasts; Mice; Mice, Inbred C3H; Neoplasms, Radiation-Induced; Tetradecanoylphorbol Acetate; Ultrasonics

1989
[Cell adhesion in rat fibroblasts: effect of tumor promoters].
    Bollettino della Societa italiana di biologia sperimentale, 1989, Volume: 65, Issue:5

    Topics: Animals; Bee Venoms; Cell Adhesion; Cell Transformation, Neoplastic; Cells, Cultured; Fibroblasts; Melitten; Rats; Tetradecanoylphorbol Acetate

1989
Response of neoplasms of B cell lineage to the proliferative effects of B cell growth factor and the phorbol ester TPA.
    The American journal of pathology, 1989, Volume: 134, Issue:4

    Topics: B-Lymphocytes; Cell Division; Cell Transformation, Neoplastic; DNA; Humans; Interleukin-4; Interleukins; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma; Lymphoma, Non-Hodgkin; Palatine Tonsil; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tetradecanoylphorbol Acetate

1989
Regulation of transforming growth factor alpha messenger RNA expression in a chemically transformed rat hepatic epithelial cell line by phorbol ester and hormones.
    Cancer research, 1989, Jul-01, Volume: 49, Issue:13

    Topics: Animals; Cell Transformation, Neoplastic; Cycloheximide; Epidermal Growth Factor; ErbB Receptors; Gene Expression Regulation; Hormones; In Vitro Techniques; Liver; Protein Kinase C; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Transcription, Genetic; Transforming Growth Factors

1989
The effect of 12-O-tetradecanoylphorbol-13-acetate (TPA) on leukemic cells from chronic B cell leukemia.
    Leukemia, 1989, Volume: 3, Issue:7

    Topics: B-Lymphocytes; Cell Adhesion; Cell Differentiation; Cell Transformation, Neoplastic; Histocytochemistry; Humans; Leukemia, Hairy Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Tetradecanoylphorbol Acetate

1989
Tumorigenic conversion of xeroderma pigmentosum lymphoblastoid cells without karyotypic alteration.
    International journal of cancer, 1989, Oct-15, Volume: 44, Issue:4

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Humans; Karyotyping; Lymphocyte Transfusion; Lymphocytes; Mice; Mice, Inbred BALB C; Mice, Nude; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Tumor Stem Cell Assay; Ultraviolet Rays; Xeroderma Pigmentosum

1989
Improvement of carcinogen identification in BALB/3T3 cell transformation by application of a 2-stage method.
    Mutation research, 1989, Volume: 214, Issue:2

    Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Methylnitronitrosoguanidine; Mice; Mice, Inbred BALB C; Mutagens; Tetradecanoylphorbol Acetate

1989
Differential expression of an 80-kDa protein kinase C substrate in preneoplastic and neoplastic mouse JB6 cells.
    Proceedings of the National Academy of Sciences of the United States of America, 1989, Volume: 86, Issue:19

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Mice; Mice, Inbred BALB C; Neoplasm Proteins; Neoplasms, Experimental; Phosphorylation; Precancerous Conditions; Protein Kinase C; Substrate Specificity; Tetradecanoylphorbol Acetate

1989
Tumour initiatory activity of a herbicide diuron on mouse skin.
    Cancer letters, 1989, Nov-30, Volume: 48, Issue:2

    Topics: Animals; Cell Transformation, Neoplastic; Diuron; Dose-Response Relationship, Drug; Drug Synergism; Mice; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors

1989
Early superoxide dismutase-sensitive event promotes neoplastic transformation in mouse epidermal JB6 cells.
    Carcinogenesis, 1988, Volume: 9, Issue:2

    Topics: Animals; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Glutathione Peroxidase; Mice; Superoxide Dismutase; Superoxides; Tetradecanoylphorbol Acetate

1988
Effect of diterpene esters on actin cytoskeleton of SV40-transformed keratinocytes is not reproduced by diacylglycerols.
    Carcinogenesis, 1988, Volume: 9, Issue:2

    Topics: Actins; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cytoskeleton; Diglycerides; Diterpenes; Esters; Glycerides; Humans; Simian virus 40; Tetradecanoylphorbol Acetate

1988
Characterization of the transformation properties of Shope fibroma virus.
    Virus research, 1988, Volume: 9, Issue:1

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cocarcinogenesis; DNA, Viral; Fibroblasts; Fibroma Virus, Rabbit; Mice; Neoplasms, Experimental; Poxviridae; Rabbits; Tetradecanoylphorbol Acetate; Transfection; Ultraviolet Rays

1988
Proto-oncogene fos: factors affecting expression and covalent modification of the gene product.
    Annals of the New York Academy of Sciences, 1987, Volume: 511

    Topics: Animals; Blood Physiological Phenomena; Cattle; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Fibroblasts; Gene Expression Regulation; Gene Products, gag; Phosphorylation; Protein Kinases; Protein Processing, Post-Translational; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogenes; Rats; Retroviridae Proteins; Sarcoma Viruses, Murine; Tetradecanoylphorbol Acetate; Transcription, Genetic

1987
Vasopressin, phorbol diesters and serum elicit choline glycerophospholipid hydrolysis and diacylglycerol formation in nontransformed cells: transformed derivatives do not respond.
    Biochimica et biophysica acta, 1988, Mar-04, Volume: 959, Issue:1

    Topics: Animals; Blood; Cell Line; Cell Transformation, Neoplastic; Culture Media; Diglycerides; Embryo, Mammalian; Glycerides; Kinetics; Phorbol Esters; Phosphatidylcholines; Rats; Simian virus 40; Tetradecanoylphorbol Acetate; Vasopressins

1988
Phospholipid-sensitive, Ca2+-dependent protein kinase activity in rat embryo fibroblasts transformed by herpes simplex virus type 2.
    Oncology, 1988, Volume: 45, Issue:3

    Topics: Animals; Cell Transformation, Neoplastic; Cell Transformation, Viral; Embryo, Mammalian; Enzyme Induction; Fibroblasts; Neoplasm Proteins; Protein Kinase C; Rats; Rats, Inbred BUF; Simplexvirus; Tetradecanoylphorbol Acetate

1988
Colony-stimulating factor 1-mediated regulation of a chimeric c-fms/v-fms receptor containing the v-fms-encoded tyrosine kinase domain.
    Proceedings of the National Academy of Sciences of the United States of America, 1988, Volume: 85, Issue:16

    Topics: Animals; Cell Transformation, Neoplastic; Cloning, Molecular; Colony-Stimulating Factors; DNA; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogenes; Rats; Receptors, Cell Surface; Receptors, Colony-Stimulating Factor; Tetradecanoylphorbol Acetate

1988
Induction of foci of morphologically transformed cells in synchronized populations of 10T1/2 cells by N-methyl-N'-nitro-N-nitrosoguanidine and the effect of spontaneous transformation on calculated transformation frequency.
    Cancer research, 1988, Nov-01, Volume: 48, Issue:21

    Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Methylnitronitrosoguanidine; Mice; Mutation; Proto-Oncogenes; Sodium-Potassium-Exchanging ATPase; Tetradecanoylphorbol Acetate

1988
Differences in transferrin receptor function between normal developing and transformed myogenic cells as revealed by differential effects of phorbol ester on receptor distribution and rates of iron uptake.
    The Journal of biological chemistry, 1988, Oct-05, Volume: 263, Issue:28

    Topics: Animals; Avian Sarcoma Viruses; Biological Transport; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; Conalbumin; DNA Replication; Iron; Kinetics; Muscles; Phorbols; Receptors, Transferrin; Tetradecanoylphorbol Acetate

1988
Use of the orthogonal design method to study the synergistic effects of asbestos fibres and 12-O-tetradecanoylphorbol-13-acetate (TPA) in the BALB/3T3 cell transformation system.
    Mutagenesis, 1988, Volume: 3, Issue:4

    Topics: Animals; Asbestos; Asbestos, Crocidolite; Asbestos, Serpentine; Cell Transformation, Neoplastic; Cells, Cultured; Dose-Response Relationship, Drug; Drug Synergism; Mice; Mice, Inbred BALB C; Mutagenicity Tests; Mutagens; Tetradecanoylphorbol Acetate

1988
Tyrosine phosphorylation in signal transduction.
    Cold Spring Harbor symposia on quantitative biology, 1988, Volume: 53 Pt 1

    Topics: 1-Phosphatidylinositol 4-Kinase; Animals; Cell Transformation, Neoplastic; Cells, Cultured; Gene Expression Regulation; Immunoblotting; Mice; Mice, Inbred Strains; Peptide Mapping; Phosphorylation; Phosphotransferases; Platelet-Derived Growth Factor; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogenes; Signal Transduction; Tetradecanoylphorbol Acetate; Tyrosine

1988
Polyoma middle T abrogates TPA requirement of murine melanocytes and induces malignant melanoma.
    Oncogene, 1988, Volume: 3, Issue:5

    Topics: Animals; Antigens, Polyomavirus Transforming; Blotting, Northern; Blotting, Western; Cell Line; Cell Transformation, Neoplastic; Melanocytes; Melanoma, Experimental; Mice; Polyomavirus; Protein Kinase C; Proto-Oncogenes; Tetradecanoylphorbol Acetate; Transfection

1988
Promotion-like enhancement of transformed phenotypes in human endometrial stromal cells.
    Carcinogenesis; a comprehensive survey, 1985, Volume: 8

    Topics: Cell Transformation, Neoplastic; Cells, Cultured; Diethylstilbestrol; Endometrium; Female; gamma-Glutamyltransferase; Humans; L-Lactate Dehydrogenase; Methylnitronitrosoguanidine; Phenotype; Tetradecanoylphorbol Acetate

1985
Inhibition of epidermal terminal differentiation and tumour promotion by retinoids.
    Ciba Foundation symposium, 1985, Volume: 113

    Topics: Acyltransferases; Animals; Antineoplastic Agents; Cell Differentiation; Cell Transformation, Neoplastic; Cells, Cultured; Enzyme Induction; Epidermis; Growth Inhibitors; Mice; Mice, Inbred BALB C; Retinoids; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transglutaminases

1985
Effects of retinoic acid on the transformation and metabolic cooperation of rat liver cells in vitro, and on the growth of hepatoma cells in vivo.
    Carcinogenesis, 1986, Volume: 7, Issue:4

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Drug Synergism; gamma-Glutamyltransferase; Liver; Liver Neoplasms, Experimental; Rats; Rats, Inbred F344; Tetradecanoylphorbol Acetate; Tretinoin

1986
Transformation studies on human fibroblasts from familial polyposis coli patients and normal donors.
    Mutation research, 1988, Volume: 199, Issue:2

    Topics: Adenomatous Polyposis Coli; Cell Division; Cell Transformation, Neoplastic; Fibroblasts; Humans; Kinetics; Methylnitronitrosoguanidine; Multiple Endocrine Neoplasia; Neoplasms; Skin; Tetradecanoylphorbol Acetate

1988
Effect of X-ray dose protraction and a tumor promoter on transformation induction in vitro.
    International journal of radiation biology, 1988, Volume: 54, Issue:1

    Topics: Animals; Carcinogens; Cell Line; Cell Survival; Cell Transformation, Neoplastic; In Vitro Techniques; Mice; Tetradecanoylphorbol Acetate; Time Factors

1988
Effect of growth state, tumor promoters, and transformation upon intercellular communication between C3H/10T1/2 murine fibroblasts.
    Carcinogenesis, 1989, Volume: 10, Issue:1

    Topics: Animals; Carcinogens; Cell Communication; Cell Line; Cell Transformation, Neoplastic; Isoquinolines; Methylcholanthrene; Methylnitronitrosoguanidine; Mice; Polychlorinated Dibenzodioxins; Tetradecanoylphorbol Acetate

1989
Regulation of collagen VI expression in fibroblasts. Effects of cell density, cell-matrix interactions, and chemical transformation.
    The Journal of biological chemistry, 1989, Feb-25, Volume: 264, Issue:6

    Topics: Actins; Animals; Blotting, Northern; Cell Count; Cell Line; Cell Transformation, Neoplastic; Collagen; Disulfides; DNA Probes; Fibronectins; Gene Expression Regulation; Guanidine; Guanidines; Humans; Mice; Nucleic Acid Hybridization; RNA, Messenger; Tetradecanoylphorbol Acetate

1989
Induction of neoplastic transformation in C3H/10T1/2 cells by 2.45-GHz microwaves and phorbol ester.
    Radiation research, 1989, Volume: 117, Issue:3

    Topics: Animals; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Microwaves; Tetradecanoylphorbol Acetate

1989
Induction of integrated adenovirus E1A and E1B genes in transformed human cells by phorbol ester tumor promoters.
    Cancer research, 1987, Feb-01, Volume: 47, Issue:3

    Topics: Adenovirus Early Proteins; Adenoviruses, Human; Cell Line; Cell Transformation, Neoplastic; Cloning, Molecular; Cycloheximide; DNA; Genes; Genes, Viral; Humans; KB Cells; Kinetics; Oncogene Proteins, Viral; Phorbol Esters; Tetradecanoylphorbol Acetate; Transcription, Genetic

1987
Myeloid antigen expression on common acute lymphatic leukaemia blasts after culture.
    Leukemia research, 1988, Volume: 12, Issue:7

    Topics: Adult; Antigens, Differentiation; Antigens, Differentiation, Myelomonocytic; Antigens, Neoplasm; Cell Transformation, Neoplastic; Child; Child, Preschool; Humans; Infant; Middle Aged; Neprilysin; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1988
Conditional immortalization and/or transformation of rat cells carrying v-abl or EJras oncogene in the presence or absence of glucocorticoid hormone.
    International journal of cancer, 1988, Dec-15, Volume: 42, Issue:6

    Topics: Adenovirus Early Proteins; Animals; Cell Transformation, Neoplastic; Cells, Cultured; DNA; Genes, ras; Glucocorticoids; Oncogene Proteins, Viral; Oncogenes; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate; Transfection

1988
Role of reactive oxygen in tumor promotion: implication of superoxide anion in promotion of neoplastic transformation in JB-6 cells by TPA.
    Carcinogenesis, 1985, Volume: 6, Issue:2

    Topics: Animals; Antioxidants; Arachidonic Acid; Arachidonic Acids; Cell Line; Cell Transformation, Neoplastic; Cocarcinogenesis; Hydroxides; Hydroxyl Radical; Lipoxygenase Inhibitors; Mannitol; Mice; Phorbols; Skin Neoplasms; Superoxide Dismutase; Superoxides; Tetradecanoylphorbol Acetate

1985
A transforming activity not detected by DNA transfer to NIH 3T3 cells is detected by JB6 mouse epidermal cells.
    Molecular and cellular biology, 1985, Volume: 5, Issue:4

    Topics: Animals; Cell Adhesion; Cell Line; Cell Transformation, Neoplastic; Contact Inhibition; DNA; DNA Restriction Enzymes; Epidermal Cells; Mice; Phenotype; Tetradecanoylphorbol Acetate; Transfection

1985
Caffeine and other phosphodiesterase inhibitors are potent inhibitors of the promotional effect of TPA on morphological transformation of hamster embryo cells.
    Cancer letters, 1985, Volume: 28, Issue:1

    Topics: Adenylyl Cyclases; Animals; Bucladesine; Caffeine; Cell Communication; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Cyclic AMP; Mesocricetus; Phorbols; Phosphodiesterase Inhibitors; Tetradecanoylphorbol Acetate

1985
Are free radicals involved in tumor promotion?
    Chemico-biological interactions, 1985, Volume: 54, Issue:2

    Topics: Animals; Antioxidants; Butylated Hydroxyanisole; Cell Transformation, Neoplastic; Cytochrome c Group; Dose-Response Relationship, Drug; Free Radicals; Hydrogen Peroxide; Nitroblue Tetrazolium; Superoxides; Tetradecanoylphorbol Acetate; Time Factors

1985
Site-specific increased phosphorylation of pp60v-src after treatment of RSV-transformed cells with a tumor promoter.
    Science (New York, N.Y.), 1985, Sep-27, Volume: 229, Issue:4720

    Topics: Animals; Arvicolinae; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Dimethyl Sulfoxide; ErbB Receptors; Mice; Mice, Inbred BALB C; Oncogene Protein pp60(v-src); Phorbol Esters; Phosphorylation; Protein Kinase C; Protein Kinases; Receptors, Cell Surface; Sarcoma, Avian; Tetradecanoylphorbol Acetate; Viral Proteins

1985
Ribosomal protein S6 phosphorylation and morphological changes in response to the tumour promoter 12-O-tetradecanoylphorbol 13-acetate in primary human tumour cells, established and transformed cell lines.
    Biochimica et biophysica acta, 1985, Oct-30, Volume: 847, Issue:1

    Topics: Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Fibroblasts; Glioma; Humans; Meningeal Neoplasms; Meningioma; Neoplasms; Phosphorylation; Ribosomal Proteins; Simian virus 40; Tetradecanoylphorbol Acetate

1985
The extracellular matrix of normal chick embryo fibroblasts: its effect on transformed chick fibroblasts and its proteolytic degradation by the transformants.
    The Journal of cell biology, 1985, Volume: 101, Issue:5 Pt 1

    Topics: Animals; Avian Sarcoma Viruses; Cell Fractionation; Cell Transformation, Neoplastic; Cells, Cultured; Chick Embryo; Extracellular Matrix; Fibroblasts; Kinetics; Microscopy, Electron; Molecular Weight; Plasminogen; Tetradecanoylphorbol Acetate

1985
Regulation of cell differentiation and tumor promotion by 1 alpha,25 dihydroxyvitamin D3.
    Carcinogenesis; a comprehensive survey, 1985, Volume: 10

    Topics: Animals; Calcitriol; Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; Cricetinae; Enzyme Induction; Humans; Lymphocytes; Melanins; Melanoma; Mice; Ornithine Decarboxylase; Protein Kinase C; Receptors, Calcitriol; Receptors, Steroid; Skin; Tetradecanoylphorbol Acetate

1985
Differential effects of the tumor promoter phorbol-12-myristate-13-acetate on the morphological and biochemical differentiation of N-18 mouse neuroblastoma cells.
    Journal of cellular physiology, 1985, Volume: 125, Issue:3

    Topics: Acetylcholinesterase; Animals; Axons; Bucladesine; Carrier Proteins; Cell Transformation, Neoplastic; Cells, Cultured; Cyclic AMP Receptor Protein; Fetal Blood; Growth Inhibitors; Mice; Neuroblastoma; Phorbols; Tetradecanoylphorbol Acetate

1985
Tumor promoters in conjunction with calcium ionophores mimic antigenic stimulation by reactivation of alloantigen-primed murine T lymphocytes.
    Journal of immunology (Baltimore, Md. : 1950), 1985, Volume: 135, Issue:6

    Topics: Animals; Calcimycin; Carcinogens; Cell Transformation, Neoplastic; Clone Cells; Cyclic AMP; Cyclosporins; Cytotoxicity, Immunologic; Drug Synergism; Egtazic Acid; Female; Immunosuppressive Agents; Interleukin-2; Isoantigens; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Protein Kinase C; Rats; Rats, Inbred Lew; Receptors, Immunologic; Receptors, Interleukin-2; T-Lymphocytes; Tetradecanoylphorbol Acetate

1985
Enhancement by 1 alpha,25-dihydroxyvitamin D3 of chemically induced transformation of BALB 3T3 cells without induction of ornithine decarboxylase or activation of protein kinase C1.
    Cancer research, 1986, Volume: 46, Issue:2

    Topics: Animals; Caenorhabditis elegans Proteins; Calcitriol; Carrier Proteins; Cell Line; Cell Survival; Cell Transformation, Neoplastic; DNA; Drug Synergism; Enzyme Activation; Enzyme Induction; Epidermal Growth Factor; ErbB Receptors; Methylcholanthrene; Mice; Ornithine Decarboxylase; Protein Kinase C; Receptors, Cell Surface; Receptors, Drug; Receptors, Immunologic; Tetradecanoylphorbol Acetate

1986
Differential effects of phorbol ester on the beta-adrenergic response of normal and ras-transformed NIH3T3 cells.
    Biochemical and biophysical research communications, 1985, Dec-17, Volume: 133, Issue:2

    Topics: Animals; Base Sequence; Cell Line; Cell Transformation, Neoplastic; Cyclic AMP; DNA, Neoplasm; Fibroblasts; Humans; Isoproterenol; Mice; Mice, Nude; Oncogenes; Phenotype; Phorbols; Receptors, Adrenergic, beta; Tetradecanoylphorbol Acetate; Urinary Bladder Neoplasms

1985
Cloning and characterization of putative genes that specify sensitivity to neoplastic transformation by tumor promoters.
    International journal of cancer, 1986, Feb-15, Volume: 37, Issue:2

    Topics: Amino Acid Sequence; Animals; Base Sequence; Cell Transformation, Neoplastic; Cloning, Molecular; DNA Restriction Enzymes; Genes; Haplorhini; Humans; Mice; Mice, Inbred BALB C; Nucleic Acid Hybridization; Oncogenes; Phenotype; Plasmids; Tetradecanoylphorbol Acetate

1986
12-O-Tetradecanoylphorbol-13-acetate (TPA)-induced gene sequences in human primary diploid fibroblasts and their expression in SV40-transformed fibroblasts.
    Journal of cellular biochemistry, 1985, Volume: 29, Issue:4

    Topics: Bloom Syndrome; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; DNA; Fibroblasts; Gene Expression Regulation; Humans; Phorbols; RNA, Messenger; Simian virus 40; Tetradecanoylphorbol Acetate; Xeroderma Pigmentosum

1985
Effect of phorbol esters on the activity of purified transforming growth factors.
    Cancer research, 1986, Volume: 46, Issue:4 Pt 1

    Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Drug Synergism; Epidermal Growth Factor; ErbB Receptors; Kidney; Peptides; Phorbols; Rats; Receptors, Cell Surface; Tetradecanoylphorbol Acetate; Transforming Growth Factors

1986
The oncogene of BAV-3 as a mutagen.
    Journal of cell science, 1985, Volume: 78

    Topics: Adenoviridae; Animals; Cattle; Cell Transformation, Neoplastic; Cricetinae; Cricetulus; Deoxyribonuclease EcoRI; DNA Restriction Enzymes; DNA, Viral; Drug Resistance; Mercaptopurine; Mesocricetus; Mutation; Oncogenes; Plasmids; Tetradecanoylphorbol Acetate

1985
Enhanced protein phosphorylation of carcinogen-initiated 10T1/2 cells accompanies their neoplastic transformation.
    Carcinogenesis, 1986, Volume: 7, Issue:8

    Topics: Animals; Calcium; Cell Transformation, Neoplastic; Cells, Cultured; Culture Media; Diterpenes; ErbB Receptors; Mice; Molecular Weight; Phosphates; Phosphoproteins; Phosphorylation; Proteins; Receptors, Cell Surface; Retinyl Esters; Tetradecanoylphorbol Acetate; Vitamin A

1986
Induction of an unusual type of shared phosphorylation in human and avian cells by tumor-promoting phorbol esters or transformation.
    Cancer research, 1986, Volume: 46, Issue:10

    Topics: Amino Acids; Animals; Avian Sarcoma Viruses; Cell Transformation, Neoplastic; Cells, Cultured; Chick Embryo; Diglycerides; Fibroblasts; Humans; Molecular Weight; Peptide Mapping; Phosphorylation; Protein Kinase C; Proteins; Tetradecanoylphorbol Acetate

1986
Induction of anchorage-independent growth of JB6 mouse epidermal cells by 1 alpha,25-dihydroxyvitamin D3.
    Cancer research, 1986, Volume: 46, Issue:11

    Topics: Animals; Calcitriol; Carcinogens; Cell Adhesion; Cell Cycle; Cell Line; Cell Transformation, Neoplastic; DNA; DNA Replication; DNA-Binding Proteins; Epidermal Cells; Mice; Receptors, Calcitriol; Receptors, Steroid; Tetradecanoylphorbol Acetate; Tretinoin

1986
Coordinate regulation of myelomonocytic phenotype by v-myb and v-myc.
    Molecular and cellular biology, 1986, Volume: 6, Issue:5

    Topics: Animals; Avian Leukosis Virus; Avian Myeloblastosis Virus; Avian Sarcoma Viruses; Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; Chick Embryo; Genes, Viral; Oncogenes; Phenotype; Tetradecanoylphorbol Acetate

1986
Inhibition of biological actions of 12-O-tetradecanoylphorbol-13-acetate by inhibitors of protein kinase C.
    Japanese journal of cancer research : Gann, 1986, Volume: 77, Issue:11

    Topics: Animals; Cell Communication; Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; Diglycerides; Mice; Palmitoylcarnitine; Phloretin; Protein Kinase C; Superoxides; Tetradecanoylphorbol Acetate

1986
Differential response to retinoic acid of Syrian hamster embryo fibroblasts expressing v-src or v-Ha-ras oncogenes.
    Molecular and cellular biology, 1986, Volume: 6, Issue:10

    Topics: Animals; Avian Sarcoma Viruses; Cell Division; Cell Line; Cell Transformation, Neoplastic; Embryo, Mammalian; Fibroblasts; Genes; Genes, Viral; Guinea Pigs; Kinetics; Oncogene Protein p21(ras); Oncogene Protein pp60(v-src); Oncogene Proteins, Viral; Oncogenes; Ornithine Decarboxylase; Retroviridae Proteins; Tetradecanoylphorbol Acetate; Tretinoin

1986
Defects of cyclic adenosine 3':5'-monophosphate-dependent protein kinases in initiated clones derived from BALB/c 3T3 mouse fibroblasts.
    Cancer research, 1987, Feb-15, Volume: 47, Issue:4

    Topics: 4-Nitroquinoline-1-oxide; Animals; Cell Division; Cell Line; Cell Transformation, Neoplastic; Clone Cells; Cyclic AMP; Ethyl Methanesulfonate; Fibroblasts; Methylnitronitrosoguanidine; Mice; Mice, Inbred BALB C; Protein Kinases; Tetradecanoylphorbol Acetate

1987
DNA sequences in human nasopharyngeal carcinoma cells that specify susceptibility to tumor promoter-induced neoplastic transformation.
    Carcinogenesis, 1987, Volume: 8, Issue:1

    Topics: Animals; Base Sequence; Cell Line; Cell Transformation, Neoplastic; DNA; DNA Restriction Enzymes; DNA, Neoplasm; Herpesvirus 4, Human; Humans; Mice; Nasopharyngeal Neoplasms; Tetradecanoylphorbol Acetate; Transfection

1987
Coordinate regulation of stromelysin and collagenase genes determined with cDNA probes.
    Proceedings of the National Academy of Sciences of the United States of America, 1987, Volume: 84, Issue:9

    Topics: Animals; Cell Transformation, Neoplastic; Cloning, Molecular; DNA; DNA Restriction Enzymes; Endopeptidases; Genes; Genes, Regulator; Matrix Metalloproteinase 3; Microbial Collagenase; Nucleic Acid Hybridization; Protein Biosynthesis; Rabbits; Synovial Fluid; Tetradecanoylphorbol Acetate; Transcription, Genetic

1987
Inhibition of 12-O-tetradecanoylphorbol-13-acetate-enhanced transformation in vitro by radical scavengers.
    Cancer letters, 1987, Volume: 35, Issue:2

    Topics: Animals; Catalase; Cell Transformation, Neoplastic; Free Radicals; Hydrogen Peroxide; Mannitol; Mice; Mice, Inbred BALB C; Superoxide Dismutase; Superoxides; Tetradecanoylphorbol Acetate

1987
'Water structure' versus 'radical scavenger' theories as explanations for the suppressive effects of DMSO and related compounds on radiation-induced transformation in vitro.
    Carcinogenesis, 1987, Volume: 8, Issue:5

    Topics: Acetamides; Cell Transformation, Neoplastic; Cells, Cultured; Dimethyl Sulfoxide; Dimethylformamide; Dose-Response Relationship, Drug; Hydroxides; Hydroxyl Radical; Neoplasms, Radiation-Induced; Tetradecanoylphorbol Acetate; Water

1987
Effect of phorbol myristate acetate on cultured tumor cells derived from different stages of avian sarcoma virus (ASV)-induced neoplastic growth.
    Experimental biology, 1987, Volume: 46, Issue:4

    Topics: Animals; Avian Sarcoma Viruses; Cell Transformation, Neoplastic; Chick Embryo; Chickens; Fibroblasts; Oncogene Protein pp60(v-src); Protein Kinases; Retroviridae Proteins; Sarcoma, Avian; Sarcoma, Experimental; Tetradecanoylphorbol Acetate

1987
[Reversal of malignant transformation induced by the oncogenic virus SV40. I. Induction of reversal to normal type for the contact inhibition trait].
    Genetika, 1987, Volume: 23, Issue:4

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Contact Inhibition; Cricetinae; Cricetulus; Mutation; Phenotype; Simian virus 40; Tetradecanoylphorbol Acetate

1987
Partial down-regulation of protein kinase C in C3H 10T 1/2 mouse fibroblasts transfected with the human Ha-ras oncogene.
    Cancer research, 1988, Nov-15, Volume: 48, Issue:22

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Fibroblasts; Genes, ras; Humans; Isoenzymes; Mice; Protein Kinase C; Tetradecanoylphorbol Acetate; Transfection

1988
Sodium fluoride promotes morphological transformation of Syrian hamster embryo cells.
    Carcinogenesis, 1988, Volume: 9, Issue:12

    Topics: Animals; Benzo(a)pyrene; Cell Transformation, Neoplastic; Cells, Cultured; Cocarcinogenesis; Fluorides; Genes, ras; Phenotype; Phosphates; Sodium Fluoride; Tetradecanoylphorbol Acetate

1988
Modified responsiveness of v-Ha-ras-transfected rat fibroblasts to growth factors and a tumor promoter.
    Molecular carcinogenesis, 1988, Volume: 1, Issue:2

    Topics: Animals; Blotting, Northern; Bombesin; Carcinogenicity Tests; Carcinogens; Cell Adhesion; Cell Transformation, Neoplastic; Cells, Cultured; Epidermal Growth Factor; Fibroblasts; Mice; Mice, Nude; Oncogenes; Phenotype; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); Rats; Tetradecanoylphorbol Acetate; Transfection

1988
Extracellular calcium requirement for promotion of transformation in JB6 cells.
    Cancer research, 1986, Volume: 46, Issue:2

    Topics: Animals; Calcimycin; Calcium; Cell Line; Cell Transformation, Neoplastic; Egtazic Acid; Extracellular Space; Lanthanum; Mice; Nifedipine; Phorbols; Tetradecanoylphorbol Acetate

1986
Retinoic acid enhancement of an early step in the transformation of mouse epidermal cells in vitro.
    Carcinogenesis, 1986, Volume: 7, Issue:9

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Cell Line; Cell Transformation, Neoplastic; Cocarcinogenesis; Dose-Response Relationship, Drug; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin

1986
Effects of 12-O-tetradecanoylphorbol-13-acetate on carcinogen-induced mouse mammary lesions in organ culture.
    Cancer research, 1986, Volume: 46, Issue:11

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Differentiation; Cell Transformation, Neoplastic; Drug Synergism; Female; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Organ Culture Techniques; Tetradecanoylphorbol Acetate

1986
Altered expression of oncogenes in mouse epidermis following exposure to benzo(a)pyrene diol epoxides.
    Advances in experimental medicine and biology, 1986, Volume: 197

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Cell Transformation, Neoplastic; Dihydroxydihydrobenzopyrenes; DNA, Neoplasm; Female; Mice; Mice, Inbred Strains; Nucleic Acid Hybridization; Oncogenes; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate

1986
Possible involvement of a lanthanide-sensitive protein kinase C substrate in lanthanide promotion of neoplastic transformation.
    Carcinogenesis, 1986, Volume: 7, Issue:12

    Topics: Calcimycin; Calcium Channel Blockers; Cell Line; Cell Transformation, Neoplastic; Enzyme Activation; ErbB Receptors; Metals, Rare Earth; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate

1986
Oncogene-induced transformation of a rat embryo fibroblast cell line is enhanced by tumor promoters.
    Molecular and cellular biology, 1986, Volume: 6, Issue:6

    Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Fibroblasts; Lyngbya Toxins; Mice; Oncogenes; Rats; Tetradecanoylphorbol Acetate; Transfection

1986
Effect of retinoic acid and phorbol-12-myristate-13-acetate on glycosyltransferase activities in normal and transformed cells.
    Cancer research, 1987, Feb-01, Volume: 47, Issue:3

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Clone Cells; Cricetinae; Galactosyltransferases; Kinetics; Retroviridae; Sialyltransferases; Tetradecanoylphorbol Acetate; Tretinoin

1987
Skin tumor promotion is associated with increased type V collagen content in the dermis.
    Carcinogenesis, 1987, Volume: 8, Issue:1

    Topics: Animals; Calcimycin; Cell Transformation, Neoplastic; Collagen; Epidermis; Female; Mice; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate

1987
Elevated levels of glucose transport and transporter messenger RNA are induced by ras or src oncogenes.
    Science (New York, N.Y.), 1987, Mar-20, Volume: 235, Issue:4795

    Topics: Animals; Cell Division; Cell Membrane; Cell Transformation, Neoplastic; Deoxyglucose; Gene Expression Regulation; Glucose; GTP-Binding Proteins; Monosaccharide Transport Proteins; Oncogenes; Protein-Tyrosine Kinases; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate; Transfection

1987
The lack of PDGE-stimulated PGE2 release from ras-transformed NIH-3T3 cells results from reduced phospholipase C but not phospholipase A2 activity.
    Biochemical and biophysical research communications, 1987, Jun-30, Volume: 145, Issue:3

    Topics: Animals; Calcimycin; Cell Transformation, Neoplastic; Cells, Cultured; Dinoprostone; Kinetics; Mice; Mice, Inbred Strains; Oncogenes; Phospholipases; Phospholipases A; Phospholipases A2; Platelet-Derived Growth Factor; Prostaglandins E; Tetradecanoylphorbol Acetate; Type C Phospholipases

1987
Pleiotropic effects of quercetin on the transformation of BALB 3T3 cells.
    Japanese journal of cancer research : Gann, 1987, Volume: 78, Issue:8

    Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Depression, Chemical; Flavonoids; In Vitro Techniques; Methylcholanthrene; Mice; Quercetin; Stimulation, Chemical; Tetradecanoylphorbol Acetate

1987
Differentiating among proposed mechanisms for tumor promotion in mouse skin with the use of the multievent model for cancer.
    Journal of the National Cancer Institute, 1987, Volume: 79, Issue:4

    Topics: 4-Nitroquinoline-1-oxide; Acetone; Animals; Cell Transformation, Neoplastic; Mathematics; Mice; Models, Biological; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Urethane

1987
Rapid phosphorylation of a specific 33-kDa protein (p33) associated with growth stimulated by murine and rat IL3 in different IL3-dependent cell lines, and its constitutive expression in a malignant independent clone.
    Leukemia, 1988, Volume: 2, Issue:2

    Topics: Adenosine Triphosphate; Animals; Calcimycin; Cell Division; Cell Line; Cell Transformation, Neoplastic; Clone Cells; Concanavalin A; Culture Media; Interleukin-3; Interleukin-4; Interleukins; Kinetics; Mice; Molecular Weight; Phosphoproteins; Phosphorylation; Protein Kinase C; Rats; Recombinant Proteins; Spleen; Tetradecanoylphorbol Acetate

1988
Clinical application of phorbol diester-induced leukemic cell differentiation for the definite diagnosis of acute leukemias.
    Japanese journal of cancer research : Gann, 1988, Volume: 79, Issue:3

    Topics: Acute Disease; Adolescent; Adult; Cell Differentiation; Cell Transformation, Neoplastic; Diagnosis, Differential; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Middle Aged; Tetradecanoylphorbol Acetate

1988
Proto-oncogene fos expression and post-translational modification.
    Progress in clinical and biological research, 1988, Volume: 266

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Fibroblasts; Gene Expression Regulation; Gene Products, gag; Mice; Phosphorylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogenes; Recombinant Fusion Proteins; Retroviridae Proteins; Tetradecanoylphorbol Acetate

1988
Comparison of mouse pro-1 and pro-2 transfectants for responses to tumor promoters and antipromoters.
    Cancer research, 1988, Nov-01, Volume: 48, Issue:21

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Diethylhexyl Phthalate; Egtazic Acid; Epidermal Growth Factor; Mice; Mice, Inbred BALB C; Protein Kinase C; Tetradecanoylphorbol Acetate; Transfection

1988
Isolation and characterization of ras-transfected BALB/3T3 clone showing morphological transformation by 12-O-tetradecanoyl-phorbol-13-acetate.
    Japanese journal of cancer research : Gann, 1988, Volume: 79, Issue:8

    Topics: Animals; Cell Division; Cell Transformation, Neoplastic; Clone Cells; DNA; Genes, ras; Mice; Nucleic Acid Hybridization; Plasmids; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured

1988
Tumor promoter 12-O-tetradecanoylphorbol-13-acetate receptors in normal human transitional epithelial cells.
    Carcinogenesis, 1985, Volume: 6, Issue:3

    Topics: Caenorhabditis elegans Proteins; Carrier Proteins; Cell Transformation, Neoplastic; Cells, Cultured; Epithelium; Humans; Phorbols; Protein Kinase C; Protein Kinases; Receptors, Drug; Receptors, Immunologic; Tetradecanoylphorbol Acetate; Tritium; Ureter

1985
Genes and signal transduction in tumor promotion: conclusions from studies with promoter resistant variants of JB-6 mouse epidermal cells.
    Carcinogenesis; a comprehensive survey, 1985, Volume: 8

    Topics: Animals; Arginine Vasopressin; Carcinogens; Carcinoma, Bronchogenic; Cell Line; Cell Transformation, Neoplastic; Cocarcinogenesis; Heat-Shock Proteins; Mice; Oncogenes; Oxidation-Reduction; Phosphatidylinositols; Protein Kinase C; Protein Kinases; Skin Neoplasms; Stress, Physiological; Tetradecanoylphorbol Acetate; Transduction, Genetic

1985
Enhanced expression of transforming growth factor beta during megakaryoblastic differentiation of K562 leukemia cells.
    Blood, 1988, Volume: 71, Issue:4

    Topics: Cell Line; Cell Transformation, Neoplastic; Cycloheximide; Humans; Leukemia, Erythroblastic, Acute; Leukemia, Megakaryoblastic, Acute; Neoplasm Proteins; Peptide Biosynthesis; Peptides; Platelet-Derived Growth Factor; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Transforming Growth Factors; Tumor Cells, Cultured

1988
Phorbol ester receptors and the induction of differentiation in the human T lymphoblastic cell line MOLT-3.
    Experimental cell biology, 1988, Volume: 56, Issue:1-2

    Topics: Caenorhabditis elegans Proteins; Carrier Proteins; Cell Differentiation; Cell Line, Transformed; Cell Transformation, Neoplastic; Drug Resistance; Humans; Leukemia-Lymphoma, Adult T-Cell; Phorbol 12,13-Dibutyrate; Protein Kinase C; Receptors, Drug; Statistics as Topic; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1988
Four-day duration of tumor promoter exposure required to transform JB6 promotion-sensitive cells to anchorage independence.
    Cancer research, 1988, Dec-15, Volume: 48, Issue:24 Pt 1

    Topics: Animals; Catalase; Cell Adhesion; Cell Line; Cell Transformation, Neoplastic; Chromatography, Affinity; Collagen; Epidermis; Hydrolases; Mice; Molecular Weight; Skin; Tetradecanoylphorbol Acetate; Time Factors

1988
Nalidixic acid and oxolinic acid reversibly suppress 3-methylcholanthrene-induced cell transformation of BALB/3T3 mouse cells.
    International journal of cancer, 1988, Dec-15, Volume: 42, Issue:6

    Topics: Animals; Cell Communication; Cell Transformation, Neoplastic; Cells, Cultured; Methylcholanthrene; Mice; Nalidixic Acid; Oxolinic Acid; Tetradecanoylphorbol Acetate; Transcription, Genetic

1988
Cocarcinogenic and tumor-promoting capabilities of anthralin.
    Archives of dermatological research, 1988, Volume: 280, Issue:7

    Topics: Animals; Anthralin; Benzo(a)pyrene; Carcinogens; Cell Transformation, Neoplastic; Cocarcinogenesis; DNA; Dose-Response Relationship, Drug; Mice; Propiolactone; Tetradecanoylphorbol Acetate

1988
Phorbol ester restores L-system amino acid transport of B lymphocytes in chronic lymphocytic leukemia.
    The Journal of clinical investigation, 1988, Volume: 81, Issue:1

    Topics: Aminoisobutyric Acids; B-Lymphocytes; Biological Transport; Cell Transformation, Neoplastic; Cycloheximide; Humans; Leucine; Leukemia, Lymphoid; Tetradecanoylphorbol Acetate

1988
Ciclosporin inhibits phorbol-ester-induced hyperplastic transformation and tumor promotion in mouse skin probably by suppression of Ca2+/calmodulin-dependent processes such as phosphorylation of elongation factor 2.
    Skin pharmacology : the official journal of the Skin Pharmacology Society, 1988, Volume: 1, Issue:2

    Topics: Animals; Calcium; Calmodulin; Cell Transformation, Neoplastic; Chromatography, DEAE-Cellulose; Cocarcinogenesis; Cycloheximide; Cyclosporins; Cytosol; Electrophoresis, Polyacrylamide Gel; Mice; Peptide Elongation Factor 2; Peptide Elongation Factors; Phosphorus Radioisotopes; Phosphorylation; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate

1988
Transfer by pro gene transfection of tumor promoter-sensitive phenotype to promotion-insensitive JB6 cells.
    Cancer research, 1988, Mar-01, Volume: 48, Issue:5

    Topics: Animals; Cell Transformation, Neoplastic; Mice; Mice, Inbred BALB C; Phenotype; Tetradecanoylphorbol Acetate; Transfection

1988
Rapid and reversible modulation of T4 (CD4) on monocytoid cells by phorbol myristate acetate: effect on HIV susceptibility.
    Cellular immunology, 1988, Apr-15, Volume: 113, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Antigens, Differentiation; Antigens, Surface; Cell Line; Cell Transformation, Neoplastic; Humans; Immunity, Innate; Kinetics; Monocytes; Tetradecanoylphorbol Acetate

1988
The transformed (initiated) human cell phenotype: study of cultured skin fibroblasts from individuals predisposed to cancer.
    Mutation research, 1988, Volume: 199, Issue:2

    Topics: Actins; Cell Transformation, Neoplastic; Cells, Cultured; Fibroblasts; Humans; Kirsten murine sarcoma virus; Moloney murine sarcoma virus; Neoplasms; Phenotype; Skin; Tetradecanoylphorbol Acetate

1988
Effects of glucocorticoid hormones on radiation induced and 12-O-tetradecanoylphorbol-13-acetate enhanced radiation transformation in vitro.
    Cancer letters, 1988, Jun-15, Volume: 40, Issue:2

    Topics: Cell Transformation, Neoplastic; Cells, Cultured; Cortisone; Dexamethasone; Glucocorticoids; Tetradecanoylphorbol Acetate

1988
Induction by growth factors from platelets of the focus-forming transformed phenotype in carcinogen-treated C3H/10T1/2 fibroblasts.
    Carcinogenesis, 1988, Volume: 9, Issue:7

    Topics: Animals; Blood Platelets; Cell Division; Cell Line; Cell Transformation, Neoplastic; Contact Inhibition; DNA; Growth Substances; Mice; Phenotype; Platelet-Derived Growth Factor; Tetradecanoylphorbol Acetate

1988
[The action mechanisms of 12-0-tetradecanoylphorbol-13-acetate (TPA) and combined effects with TPA and fibroblast growth factor on the proliferation of leukemic myeloid progenitor cells].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1987, Volume: 28, Issue:10

    Topics: Bone Marrow Cells; Cell Transformation, Neoplastic; Cells, Cultured; Fibroblast Growth Factors; Hematopoiesis; Hematopoietic Stem Cells; Humans; Leukemia; Tetradecanoylphorbol Acetate

1987
Effects of dietary retinyl palmitate or 13-cis-retinoic acid on the promotion of tumors in mouse skin.
    Cancer research, 1987, Feb-15, Volume: 47, Issue:4

    Topics: Administration, Cutaneous; Animals; Cell Transformation, Neoplastic; Diet; Diterpenes; Dose-Response Relationship, Drug; Female; Isotretinoin; Mice; Papilloma; Retinyl Esters; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Tretinoin; Vitamin A

1987
Special type of morphological reorganization induced by phorbol ester: reversible partition of cell into motile and stable domains.
    Proceedings of the National Academy of Sciences of the United States of America, 1987, Volume: 84, Issue:12

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Cytoskeleton; Fibroblasts; Microscopy, Electron; Morphogenesis; Tetradecanoylphorbol Acetate

1987
Morphological and isoenzymatic differentiation of B-chronic lymphocytic leukaemia cells induced by phorbolester.
    British journal of cancer, 1986, Volume: 53, Issue:2

    Topics: Acid Phosphatase; Aged; Antigens, Surface; B-Lymphocytes; Carboxylic Ester Hydrolases; Cell Survival; Cell Transformation, Neoplastic; Electrophoresis, Polyacrylamide Gel; Female; Hexosaminidases; Humans; In Vitro Techniques; Isoelectric Focusing; Isoenzymes; L-Lactate Dehydrogenase; Leukemia, Lymphoid; Male; Middle Aged; Tetradecanoylphorbol Acetate

1986
Activation of proto-oncogene expression by growth regulatory signals.
    Current topics in microbiology and immunology, 1986, Volume: 132

    Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Epidermal Growth Factor; Genes, Regulator; Mice; Proto-Oncogenes; Tetradecanoylphorbol Acetate

1986
Control of hsp70 RNA levels in human lymphocytes.
    The Journal of cell biology, 1987, Volume: 104, Issue:2

    Topics: Cell Line; Cell Transformation, Neoplastic; Genes; Heat-Shock Proteins; Humans; Oncogenes; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription, Genetic

1987
Bombesin induces c-fos and c-myc expression in quiescent Swiss 3T3 cells. Comparative study with other mitogens.
    Experimental cell research, 1987, Volume: 170, Issue:1

    Topics: Animals; Bombesin; Cell Transformation, Neoplastic; Cells, Cultured; DNA Replication; Epidermal Growth Factor; Mice; Mitogens; Platelet-Derived Growth Factor; Proto-Oncogenes; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic

1987
Lifespan extension of basal cell nevus syndrome fibroblasts by transfection with mouse pro or v-myc genes.
    International journal of cancer, 1987, May-15, Volume: 39, Issue:5

    Topics: Adult; Basal Cell Nevus Syndrome; Carcinoma, Basal Cell; Cell Division; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; DNA; Epidermal Growth Factor; Female; Genetic Engineering; Humans; Male; Phenotype; Tetradecanoylphorbol Acetate

1987
B cell stimulatory factor-1/interleukin-4 mRNA is expressed by normal and transformed mast cells.
    Cell, 1987, Aug-28, Volume: 50, Issue:5

    Topics: Abelson murine leukemia virus; Animals; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Female; Growth Substances; Interleukin-3; Interleukin-4; Lymphokines; Mast Cells; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Nucleic Acid Hybridization; RNA, Messenger; Tetradecanoylphorbol Acetate

1987
Effects of epidermal growth factor on transferrin receptor phosphorylation and surface expression in malignant epithelial cells.
    Journal of cellular physiology, 1987, Volume: 132, Issue:3

    Topics: Animals; Antibodies; Binding Sites; Carcinoma, Squamous Cell; Cell Line; Cell Transformation, Neoplastic; Epidermal Growth Factor; Epithelium; ErbB Receptors; Methionine; Phosphorylation; Receptors, Transferrin; Tetradecanoylphorbol Acetate; Vanadates

1987
Colony size, cell density and nature of the tumor promoter are critical variables in expression of a transformed phenotype (focus formation) in co-cultures of UV-TDTx and C3H10T1/2 cells.
    Carcinogenesis, 1987, Volume: 8, Issue:7

    Topics: Cell Count; Cell Transformation, Neoplastic; Cells, Cultured; Clone Cells; Humans; Phenotype; Tetradecanoylphorbol Acetate; Tretinoin

1987
Genes that cooperate with tumor promoters in transformation.
    Journal of cellular biochemistry, 1987, Volume: 34, Issue:2

    Topics: Animals; Base Sequence; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Genes; Humans; Protein Kinase C; Tetradecanoylphorbol Acetate; Transduction, Genetic

1987
Ornithine decarboxylase activity in foetal rat brain cells and in the mouse embryo fibroblasts C3H/10T1/2 CL8 cells: differences in response to medium change and to the tumor promoter TPA.
    The International journal of biochemistry, 1987, Volume: 19, Issue:6

    Topics: Animals; Brain; Brain Neoplasms; Cell Line; Cell Transformation, Neoplastic; Culture Media; Embryo, Mammalian; Enzyme Induction; Fibroblasts; Methylcholanthrene; Mice; Mice, Inbred C3H; Ornithine Decarboxylase; Rats; Tetradecanoylphorbol Acetate

1987
[Use of the phorbol ester differentiation test in the classification of acute leukemia].
    Zhonghua nei ke za zhi, 1987, Volume: 26, Issue:3

    Topics: Acute Disease; Adolescent; Adult; Cell Transformation, Neoplastic; Child; Child, Preschool; Diagnosis, Differential; Female; Humans; Infant; Leukemia; Male; Middle Aged; Tetradecanoylphorbol Acetate

1987
Biological and biochemical characterization of cell lines derived from initiation-promotion transformed C3H/10T1/2 cells.
    Carcinogenesis, 1987, Volume: 8, Issue:10

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; DNA; Female; Flow Cytometry; Methylcholanthrene; Mice; Mice, Inbred C3H; Molecular Weight; Peptide Biosynthesis; Tetradecanoylphorbol Acetate

1987
Possible dissociation of the phorbol ester-induced oxidant response and tumor promotion in the F1 offspring of SSIN x C57BL/6J mice.
    Carcinogenesis, 1987, Volume: 8, Issue:10

    Topics: Animals; Cell Transformation, Neoplastic; Female; Male; Mice; Mice, Inbred C57BL; Mutagenicity Tests; Oxidation-Reduction; Phorbol Esters; Tetradecanoylphorbol Acetate; Type C Phospholipases

1987
[Effect of the tumor-growth promoter 12-O-tetradecanoylphorbol-13-acetate on the proliferation of different clones of mouse tumor cells in a semiliquid medium].
    Biulleten' eksperimental'noi biologii i meditsiny, 1986, Volume: 101, Issue:4

    Topics: Animals; Cell Transformation, Neoplastic; Clone Cells; Colchicine; Culture Media; Fibroblasts; Gene Amplification; Methylcellulose; Mice; Mice, Inbred AKR; Mice, Inbred CBA; Phorbols; Sarcoma, Experimental; Tetradecanoylphorbol Acetate

1986
Use of an orthogonal design method to study two-stage chemical carcinogenesis in BALB/3T3 cells.
    Carcinogenesis, 1986, Volume: 7, Issue:6

    Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Fetal Blood; Methylnitronitrosoguanidine; Mice; Statistics as Topic; Tetradecanoylphorbol Acetate

1986
Promoting effect of 12-O-tetradecanoylphorbol-13-acetate on the in vitro malignant transformation of fetal rat brain cells exposed in utero to ethylnitrosourea.
    Cancer research, 1986, Volume: 46, Issue:3

    Topics: Animals; Brain Neoplasms; Cell Aggregation; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Cocarcinogenesis; Concanavalin A; Ethylnitrosourea; Female; Glial Fibrillary Acidic Protein; Maternal-Fetal Exchange; Neoplasm Transplantation; Neoplastic Stem Cells; Phorbols; Pregnancy; Rats; Tetradecanoylphorbol Acetate

1986
[Regulation of tumor promotion by 1 alpha, 25-dihydroxyvitamin D3, an active form of vitamin D3].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1986, Volume: 13, Issue:3 Pt 2

    Topics: Animals; Calcitriol; Calcium; Cell Differentiation; Cell Division; Cell Transformation, Neoplastic; Enzyme Activation; Mice; Mice, Inbred BALB C; Ornithine Decarboxylase; Skin Neoplasms; Tetradecanoylphorbol Acetate

1986
Antioxidants as antitumor promoters.
    Basic life sciences, 1986, Volume: 39

    Topics: Animals; Antioxidants; Cell Transformation, Neoplastic; DNA Damage; Humans; Kinetics; Mice; Nucleoproteins; Poly Adenosine Diphosphate Ribose; Skin Neoplasms; Tetradecanoylphorbol Acetate

1986
Reversible expression of morphological transformation in C3H/10T1/2 mouse embryo cultures exposed to 12-O-tetradecanoylphorbol-13-acetate.
    Carcinogenesis, 1986, Volume: 7, Issue:11

    Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Methylnitronitrosoguanidine; Mice; Phenotype; Tetradecanoylphorbol Acetate

1986
Induction of metallothionein and other mRNA species by carcinogens and tumor promoters in primary human skin fibroblasts.
    Molecular and cellular biology, 1986, Volume: 6, Issue:5

    Topics: Cell Transformation, Neoplastic; Cells, Cultured; Cloning, Molecular; DNA; Fibroblasts; Genes; Humans; Metallothionein; Nucleic Acid Hybridization; RNA, Messenger; Skin; Tetradecanoylphorbol Acetate; Transcription, Genetic

1986
Ultraviolet irradiation transforms C3H10T1/2 cells to a unique, suppressible phenotype.
    Science (New York, N.Y.), 1986, Dec-12, Volume: 234, Issue:4782

    Topics: Animals; Cell Division; Cell Line; Cell Transformation, Neoplastic; Clone Cells; Mice; Mice, Inbred C3H; Phenotype; Tetradecanoylphorbol Acetate; Ultraviolet Rays

1986
Changes in polypeptide synthesis and glycosylation in mouse embryonic fibroblast C3H/10T1/2 Cl 8 cells caused by the tumor promoter 12-O-tetradecanoylphorbol 13-acetate.
    Biochimica et biophysica acta, 1986, Dec-19, Volume: 889, Issue:3

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Embryo, Mammalian; Fibroblasts; Gene Expression Regulation; Glycoproteins; Mice; Mice, Inbred C3H; Neoplasm Proteins; Peptide Biosynthesis; Protein Processing, Post-Translational; Tetradecanoylphorbol Acetate

1986
Retinoic acid and butylated hydroxyanisole inhibit promoter-enhanced transformation in vitro.
    Cancer letters, 1986, Volume: 33, Issue:2

    Topics: Butylated Hydroxyanisole; Butylated Hydroxytoluene; Cell Transformation, Neoplastic; Cells, Cultured; Methylcholanthrene; Tetradecanoylphorbol Acetate; Tretinoin

1986
Modulation of benzo[a]pyrene-induced morphological transformation of Syrian hamster embryo cells by butylated hydroxytoluene and butylated hydroxyanisole.
    Cancer letters, 1986, Volume: 33, Issue:2

    Topics: Animals; Benzo(a)pyrene; Butylated Hydroxyanisole; Butylated Hydroxytoluene; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Mesocricetus; Tetradecanoylphorbol Acetate

1986
Neoplastic transformation in the planarian: I. Cocarcinogenesis and histopathology.
    The Journal of experimental zoology, 1986, Volume: 240, Issue:2

    Topics: Animals; Cadmium; Cadmium Compounds; Carcinogens; Cell Transformation, Neoplastic; Cocarcinogenesis; Planarians; Sulfates; Tetradecanoylphorbol Acetate; Turbellaria

1986
Neoplastic transformation in the planarian: II. Ultrastructure of malignant reticuloma.
    The Journal of experimental zoology, 1986, Volume: 240, Issue:2

    Topics: Animals; Cadmium; Cadmium Compounds; Carcinogens; Cell Transformation, Neoplastic; Cocarcinogenesis; Planarians; Sulfates; Tetradecanoylphorbol Acetate; Turbellaria

1986
Alterations of intercellular communication associated with the transformation of C3H/10T1/2 cells.
    Carcinogenesis, 1987, Volume: 8, Issue:2

    Topics: Animals; Cell Communication; Cell Line; Cell Transformation, Neoplastic; Isoquinolines; Methylcholanthrene; Mice; Polychlorinated Dibenzodioxins; Tetradecanoylphorbol Acetate

1987
Promotion, dose rate, and repair processes in radiation-induced neoplastic transformation.
    Radiation research, 1987, Volume: 109, Issue:2

    Topics: Animals; Cell Transformation, Neoplastic; DNA Repair; Dose-Response Relationship, Radiation; Mice; Mice, Inbred C3H; Tetradecanoylphorbol Acetate

1987
In vitro and in vivo activity of 12-O-3-N-dansylamino TPA.
    European journal of cancer & clinical oncology, 1986, Volume: 22, Issue:10

    Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Dansyl Compounds; Dose-Response Relationship, Drug; Mice; Tetradecanoylphorbol Acetate; Time Factors

1986
Isolation and characterization of chemically transformed pancreatic acinar cell lines from young and old mice.
    In vitro cellular & developmental biology : journal of the Tissue Culture Association, 1987, Volume: 23, Issue:2

    Topics: Acetylglucosamine; Aging; Animals; Cell Division; Cell Line; Cell Transformation, Neoplastic; Isoenzymes; Karyotyping; L-Lactate Dehydrogenase; Lectins; Male; Methylnitrosourea; Mice; Pancreatic Neoplasms; Phenotype; Plant Lectins; Soybean Proteins; Tetradecanoylphorbol Acetate

1987
Morphological transformation in three mammalian cell systems following treatment with 6-nitrochrysene and 6-nitrobenzo[a]pyrene.
    Carcinogenesis, 1987, Volume: 8, Issue:4

    Topics: Animals; Benzopyrenes; Carcinogens; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; Chrysenes; Cricetinae; Dose-Response Relationship, Drug; Phenanthrenes; Tetradecanoylphorbol Acetate

1987
Comparative effects of a complete tumor promoter, TPA, and a second-stage tumor promoter, RPA, on intercellular communication, cell differentiation and cell transformation.
    Carcinogenesis, 1985, Volume: 6, Issue:8

    Topics: Animals; Cell Communication; Cell Differentiation; Cell Transformation, Neoplastic; Cells, Cultured; Mice; Mice, Inbred BALB C; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Tetradecanoylphorbol Acetate

1985
Radiobiological issues in the anomalous enhanced effect of low-dose-rate fission-spectrum neutrons: reply to Letter to the Editor by G. W. Barendsen.
    International journal of radiation biology and related studies in physics, chemistry, and medicine, 1985, Volume: 48, Issue:1

    Topics: Animals; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; Neutrons; Radiation Dosage; Technology, Radiologic; Tetradecanoylphorbol Acetate

1985
Interaction of epidermal growth factor with initiators and complete carcinogens in the C3H10T1/2 cell culture system.
    Journal of cellular biochemistry, 1985, Volume: 28, Issue:1

    Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Cocarcinogenesis; Epidermal Growth Factor; Fibroblasts; Methylcholanthrene; Mice; Mice, Inbred C3H; Tetradecanoylphorbol Acetate; Tumor Stem Cell Assay

1985
Rapid induction of the expression of proto-oncogene fos during human monocytic differentiation.
    Cell, 1985, Volume: 40, Issue:1

    Topics: Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; Dimethyl Sulfoxide; Fluorescent Antibody Technique; Genes; Humans; Leukemia, Myeloid, Acute; Macrophages; Neoplasm Proteins; Oncogenes; Protein Biosynthesis; Proto-Oncogene Mas; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Transcription, Genetic

1985
Human acute leukemia cell line with the t(4;11) chromosomal rearrangement exhibits B lineage and monocytic characteristics.
    Blood, 1985, Volume: 65, Issue:1

    Topics: Adult; Antigens, Differentiation, B-Lymphocyte; Antigens, Neoplasm; Antigens, Surface; B-Lymphocytes; Cell Line; Cell Transformation, Neoplastic; Chromosome Aberrations; Chromosome Disorders; Clone Cells; Female; Histocytochemistry; Humans; Immunoglobulins; Karyotyping; Leukemia; Monocytes; Tetradecanoylphorbol Acetate

1985
Cyclosporin A inhibits biological effects of tumor promoting phorbol esters.
    Biochemical and biophysical research communications, 1985, Jan-16, Volume: 126, Issue:1

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cell Transformation, Neoplastic; Chromatography, Thin Layer; Cyclosporins; Edema; Female; Mice; Phorbols; Skin; Tetradecanoylphorbol Acetate; Time Factors

1985
Two-stage tumor promotion in mouse skin: an alternative interpretation.
    Journal of the National Cancer Institute, 1985, Volume: 74, Issue:4

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cocarcinogenesis; Croton Oil; Fluocinolone Acetonide; Mice; Mice, Inbred Strains; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tosylphenylalanyl Chloromethyl Ketone; Tretinoin

1985
Partial inversion of the initiation-promotion sequence of multistage tumorigenesis in the skin of NMRI mice.
    Science (New York, N.Y.), 1985, Oct-04, Volume: 230, Issue:4721

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Diterpenes; Female; Mice; Phorbol Esters; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate; Time Factors

1985
Peroxisome proliferators show tumor-promoting but no direct transforming activity in vitro.
    International journal of cancer, 1986, Jan-15, Volume: 37, Issue:1

    Topics: Adipose Tissue; Animals; Carcinogens; Cell Division; Cell Transformation, Neoplastic; Clofibrate; Dose-Response Relationship, Drug; Fatty Alcohols; Hypolipidemic Agents; Mice; Microbodies; Nicotinic Acids; Tetradecanoylphorbol Acetate

1986
Antagonistic action of a tumor promoter and a poly(adenosine diphosphoribose) synthesis inhibitor in radiation-induced transformation in vitro.
    Biochemical and biophysical research communications, 1986, Feb-13, Volume: 134, Issue:3

    Topics: Animals; Benzamides; Carcinogens; Cell Transformation, Neoplastic; Clone Cells; DNA, Neoplasm; Fibroblasts; Mice; Mice, Inbred C3H; Nucleoside Diphosphate Sugars; Poly Adenosine Diphosphate Ribose; Tetradecanoylphorbol Acetate

1986
[Role of cell-cell interaction in tumor promotion].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1986, Volume: 13, Issue:3 Pt 2

    Topics: Animals; Carcinogens; Cell Communication; Cell Transformation, Neoplastic; Cricetinae; Extracellular Space; Homeostasis; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Phorbol Esters; Protein Kinase C; Skin Neoplasms; Tetradecanoylphorbol Acetate

1986
Intercellular communication capacity as a possible determinant of transformation sensitivity of BALB/c 3T3 clonal cells.
    Cancer research, 1985, Volume: 45, Issue:2

    Topics: Animals; Cell Communication; Cell Transformation, Neoplastic; Clone Cells; Deoxyglucose; Drug Resistance; Methylcholanthrene; Mice; Mice, Inbred BALB C; Tetradecanoylphorbol Acetate

1985
Release of fibronectin is linked to tumor promotion: response of promotable and non-promotable clones of a mouse epidermal cell line.
    Carcinogenesis, 1985, Volume: 6, Issue:1

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Clone Cells; Epidermis; Fibronectins; Mice; Phorbols; Tetradecanoylphorbol Acetate; Tretinoin

1985
In vitro differentiation of human melanoma cells analyzed with monoclonal antibodies.
    Cancer research, 1985, Volume: 45, Issue:3

    Topics: Antibodies, Monoclonal; Antigens, Neoplasm; Antigens, Surface; Cell Line; Cell Transformation, Neoplastic; Humans; Melanins; Melanoma; Tetradecanoylphorbol Acetate

1985
Ultrastructural studies of spontaneous in vitro transformation of cultured marrow monocyte-macrophage cells from a patient with congenital hypoplastic anemia.
    Cancer research, 1985, Volume: 45, Issue:3

    Topics: Anemia, Aplastic; Cell Transformation, Neoplastic; Cells, Cultured; Histocytochemistry; Humans; Macrophages; Monocytes; Phagocytosis; Tetradecanoylphorbol Acetate

1985
Benzoyl peroxide promotion of transformation of JB6 mouse epidermal cells: inhibition by ganglioside GT but not retinoic acid.
    Carcinogenesis, 1985, Volume: 6, Issue:2

    Topics: Animals; Benzoyl Peroxide; Cell Line; Cell Transformation, Neoplastic; Cocarcinogenesis; Gangliosides; Mice; Peroxides; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin

1985
Phagocytes as carcinogens: malignant transformation produced by human neutrophils.
    Science (New York, N.Y.), 1985, Mar-08, Volume: 227, Issue:4691

    Topics: Animals; Cell Transformation, Neoplastic; Humans; Mice; Mice, Inbred C3H; Mice, Nude; Neutrophils; Oxidation-Reduction; Phagocytes; Tetradecanoylphorbol Acetate

1985
[TPA enhancement of the mutagenic and transforming action of bovine adenovirus type 3 on cultured mouse cells].
    Eksperimental'naia onkologiia, 1985, Volume: 7, Issue:1

    Topics: Adenoviridae; Animals; Cattle; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Mice; Mice, Inbred C3H; Mutation; Neoplasm Transplantation; Neoplasms, Experimental; Phorbols; Tetradecanoylphorbol Acetate

1985
Contrasting responses of normal and transformed rat tracheal epithelial cells to the tumor promoter 12-O-tetradecanoylphorbol-13-acetate.
    Carcinogenesis; a comprehensive survey, 1985, Volume: 8

    Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Epithelium; Phorbols; Rats; Tetradecanoylphorbol Acetate; Trachea

1985
Heterogeneity in responses of human and rodent respiratory epithelial cells to tumor promoters in culture.
    Carcinogenesis; a comprehensive survey, 1985, Volume: 8

    Topics: Animals; Bronchi; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; DNA; Epithelium; Humans; Phorbol Esters; Rats; Tetradecanoylphorbol Acetate; Trachea

1985
Enhancement and inhibition of transformation of Syrian hamster embryo cells.
    Carcinogenesis; a comprehensive survey, 1985, Volume: 8

    Topics: Animals; Asbestos; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; DNA; Embryo, Mammalian; Female; Lymphokines; Mesocricetus; Methylnitronitrosoguanidine; Polycyclic Compounds; Sulfur Dioxide; Tetradecanoylphorbol Acetate

1985
Initiation and promotion in cultures of C3H10T1/2 mouse embryo fibroblasts.
    Carcinogenesis; a comprehensive survey, 1985, Volume: 8

    Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Cocarcinogenesis; Embryo, Mammalian; Fibroblasts; Mice; Mice, Inbred C3H; Respiratory Tract Neoplasms; Skin Neoplasms; Tetradecanoylphorbol Acetate

1985
Tumor promotion and tumor progression.
    Carcinogenesis; a comprehensive survey, 1985, Volume: 8

    Topics: Animals; Cell Transformation, Neoplastic; Cocarcinogenesis; Humans; Mutation; Neoplasms; Skin Neoplasms; Tetradecanoylphorbol Acetate

1985
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) promotes the transformation of C3H/10T1/2 cells.
    Carcinogenesis, 1985, Volume: 6, Issue:4

    Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Dimethyl Sulfoxide; Dioxins; Dose-Response Relationship, Drug; Methylcholanthrene; Methylnitronitrosoguanidine; Mice; Polychlorinated Dibenzodioxins; Tetradecanoylphorbol Acetate

1985
Evidence for microwave carcinogenesis in vitro.
    Carcinogenesis, 1985, Volume: 6, Issue:6

    Topics: Animals; Benzo(a)pyrene; Cell Transformation, Neoplastic; Cocarcinogenesis; In Vitro Techniques; Mice; Microwaves; Tetradecanoylphorbol Acetate; X-Rays

1985
Inhibition of intercellular communication and enhancement of morphological transformation of Syrian hamster embryo cells by TPA. Use of TPA-sensitive and TPA-resistant cell lines.
    Carcinogenesis, 1985, Volume: 6, Issue:6

    Topics: Animals; Cell Communication; Cell Line; Cell Transformation, Neoplastic; Cricetinae; Drug Resistance; In Vitro Techniques; Mesocricetus; Phorbols; Tetradecanoylphorbol Acetate

1985
Quantitative neoplastic transformation in C3H/10T1/2 cells.
    Basic life sciences, 1985, Volume: 33

    Topics: Animals; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Kinetics; Mice; Mice, Inbred C3H; Models, Biological; Probability; Tetradecanoylphorbol Acetate

1985
Association of DNA strand breaks with accelerated terminal differentiation in mouse epidermal cells exposed to tumor promoters.
    Cancer research, 1985, Volume: 45, Issue:10

    Topics: Animals; Benzoyl Peroxide; Cell Transformation, Neoplastic; Cells, Cultured; Dimethyl Sulfoxide; DNA, Single-Stranded; Mice; Mice, Inbred BALB C; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate

1985
12-O-Tetradecanoylphorbol-13-acetate promotion of carcinogen-treated rat liver endothelial cells.
    Oncology, 1985, Volume: 42, Issue:5

    Topics: Animals; Benzo(a)pyrene; Cell Line; Cell Transformation, Neoplastic; Cocarcinogenesis; Diethylnitrosamine; Endothelium; Liver; Methylazoxymethanol Acetate; Phorbols; Rats; Tetradecanoylphorbol Acetate

1985
[Role of the oncogene in the mutagenic activity of bovine adenovirus type 3].
    Nauchnye doklady vysshei shkoly. Biologicheskie nauki, 1985, Issue:5

    Topics: Adenoviridae; Animals; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Cricetinae; Cricetulus; DNA, Viral; Dose-Response Relationship, Drug; Drug Resistance; Mercaptopurine; Mice; Mice, Inbred C3H; Mutation; Oncogenes; Tetradecanoylphorbol Acetate; Time Factors; Transfection

1985
The toxic response of preneoplastic rat tracheal epithelial cells to 12-O-tetradecanoylphorbol-13-acetate.
    Carcinogenesis, 1985, Volume: 6, Issue:10

    Topics: Animals; Cell Differentiation; Cell Division; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; Male; Phorbols; Rats; Tetradecanoylphorbol Acetate; Trachea

1985
The conditions for the modification of radiation transformation in vitro by a tumor promoter and protease inhibitors.
    Carcinogenesis, 1985, Volume: 6, Issue:10

    Topics: Animals; Antipain; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cocarcinogenesis; Mice; Oligopeptides; Phorbols; Protease Inhibitors; Tetradecanoylphorbol Acetate; Time Factors; X-Rays

1985
Mechanistic aspects of initiation and promotion in C3H/10T1/2 cells.
    Carcinogenesis; a comprehensive survey, 1985, Volume: 9

    Topics: Animals; Cell Communication; Cell Line; Cell Transformation, Neoplastic; Cocarcinogenesis; Embryo, Mammalian; Methylcholanthrene; Methylnitronitrosoguanidine; Mice; Mice, Inbred C3H; Tetradecanoylphorbol Acetate

1985
Relationship of animal cell transformation models to the study of human neoplastic cell transformation.
    Carcinogenesis; a comprehensive survey, 1985, Volume: 9

    Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Chromosome Aberrations; Cricetinae; DNA; Humans; Mesocricetus; Models, Biological; Oncogenes; Tetradecanoylphorbol Acetate

1985
Mechanisms of transformation and promotion of mouse epidermal cells.
    Carcinogenesis; a comprehensive survey, 1985, Volume: 9

    Topics: Animals; Caenorhabditis elegans Proteins; Calcium; Carrier Proteins; Cell Differentiation; Cell Transformation, Neoplastic; Cells, Cultured; Mice; Oncogenes; Protein Kinase C; Receptors, Drug; Receptors, Immunologic; Skin Neoplasms; Tetradecanoylphorbol Acetate

1985
In vitro transformation of rat tracheal epithelial cells: a model for the study of multistage carcinogenesis.
    Carcinogenesis; a comprehensive survey, 1985, Volume: 9

    Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Models, Biological; Rats; Retinoids; Tetradecanoylphorbol Acetate; Tracheal Neoplasms

1985
Potential role of treatment artifact in the effect of cell density upon frequencies of C3H/10T1/2 cell transformation.
    Cancer research, 1985, Volume: 45, Issue:12 Pt 1

    Topics: Animals; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Methylcholanthrene; Methylnitronitrosoguanidine; Mice; Research Design; Tetradecanoylphorbol Acetate

1985
Retinoids and tumorigenesis: mechanistic considerations.
    Medical oncology and tumor pharmacotherapy, 1985, Volume: 2, Issue:3

    Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Fibroblasts; Humans; Mice; Neoplasms; Retinoids; Tetradecanoylphorbol Acetate; Vitamin A; Vitamin A Deficiency

1985
A comparative study on neoplastic transformation of human and Syrian hamster cells.
    Proceedings of the National Science Council, Republic of China. Part B, Life sciences, 1985, Volume: 9, Issue:4

    Topics: Animals; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cricetinae; Embryo, Mammalian; Female; Fetus; Fibroblasts; Fibrosarcoma; Griseofulvin; Humans; Kinetics; Mesocricetus; Methylnitronitrosoguanidine; Pregnancy; Species Specificity; Tetradecanoylphorbol Acetate

1985