tetradecanoylphorbol acetate has been researched along with Cell Transformation, Neoplastic in 934 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 428 (45.82) | 18.7374 |
1990's | 267 (28.59) | 18.2507 |
2000's | 144 (15.42) | 29.6817 |
2010's | 88 (9.42) | 24.3611 |
2020's | 7 (0.75) | 2.80 |
Authors | Studies |
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Chou, P; Kong, AN; Kuo, HC; Li, S; Phadnis, A; Sargsyan, D; Sarwar, MS; Su, S; Su, X; Wang, L; Wang, Y; Wu, R | 1 |
Abe, K; Kamei, A; Ohmori, K; Watanabe, Y | 1 |
Kong, AT; Kuo, HD; Sargsyan, D; Sarwar, MS; Suh, N; Wang, C; Wu, R; Zheng, M | 1 |
Akira, S; Morisaka, H; Sano, S; Takaishi, M | 1 |
Gaté, L; Guichard, Y; Savoy, C | 1 |
Hudlikar, RR; Kong, AN; Sargsyan, D; Su, S; Wu, R; Zheng, M | 1 |
Kreft, M; Krotenberg Garcia, A; Ramovs, V; Sonnenberg, A | 1 |
Chen, Y; Qiao, Y; Sun, F; Wang, J; Wu, Q; Zhang, X; Zhao, Y; Zhu, G | 1 |
Baek, M; DiGiovanni, J; Jang, IS; Kim, DJ; Kim, M; Lee, H; Morales, LD; Slaga, TJ | 1 |
Callejas-Valera, JL; Cimas, FJ; Fernandez-Aroca, DM; Garcia-Gil, E; García-Olmo, DC; Gutkind, JS; Hernández-Losa, J; Marcos, P; Melgar-Rojas, P; Ortega-Muelas, M; Pascual-Serra, R; Ramón Y Cajal, S; Roche, O; Ruiz-Hidalgo, MJ; Sanchez-Prieto, R | 1 |
Jeong, WS; Kong, AN; Truong, VL | 1 |
Franco, R; Hernández-Franco, P; Rojas, E; Silva, M; Valverde, M | 1 |
Cao, M; Fang, M; Guo, Y; Kong, AN; Su, ZY; Wu, R; Yang, I; Yang, Y | 1 |
Balmain, A; Del Rosario, R; Harris, S; Kandyba, E; Reeves, MQ | 1 |
Balaiya, V; Johnson, LK; Koster, MI; Lakshmanachetty, S | 1 |
Li, Y; Liu, X; Lu, Y; Pei, B; Shen, W; Sun, D; Wang, X; Xiu, L; Xu, J; Yue, X; Zhang, X | 1 |
Hall, JR; House, JS; Jima, DD; Messenger, ZJ; Smart, RC; Tam, HW; Tokarz, DA | 1 |
Asfaha, S; Boland, K; Gordon, D; Jin, G; Johnson, K; Lad, S; Londono, D; Morris, RJ; Park, H; Patterson, KS; Readio, N; Singh, A; Trempus, C; Wang, TC; Yang, X | 1 |
Gubareva, EA; Maidin, MA; Panchenko, AV; Tyndyk, ML; Vinogradova, LA | 1 |
Kong, AN; Li, S; Raskin, I; Sargsyan, D; Su, S; Wang, C; Wu, R; Yin, R; Zheng, M | 1 |
DeCicco-Skinner, KL; Dempsey, TA; Deshpande, MM; Nolan, SJ; Trovato, EL; Wiest, JS | 1 |
Bajpai, P; Kumar, S; Nigam, A; Priya, S | 1 |
Cescon, D; Chio, II; Dominguez-Brauer, C; Elia, AJ; Ghazarian, D; Gorrini, C; Haight, J; Hao, Z; Harris, IS; Inoue, S; Itsumi, M; Li, WY; Mak, TW; McCracken, S; Melino, G; Penn, LJ; Sasaki, M; Silvester, J; Snow, B; Ueda, T; Wakeham, A; Yamamoto, K; You-Ten, A; Zhou, L | 1 |
Arora, N; Bansal, MP; Koul, A | 1 |
Hong, JI; Jung, BG; Kim, TH; Ko, JH; Lee, BJ; Lee, JA; Park, YS | 1 |
Hanausek, M; Junco, JJ; Kowalczyk, MC; Kowalczyk, P; Slaga, TJ; Sosnowska, R; Tolstykh, O; Walaszek, Z | 1 |
Chen, H; Ding, F; He, H; Jin, Q; Li, Y; Liu, Z; Luo, A; Ma, J; Sunkel, B; Wang, Q; Xu, C; Zhang, S | 1 |
DiGiovanni, J; Jiang, G; Kiguchi, K; Rho, O | 1 |
Fujiwara, K; Ghosh, S; Liang, P; Morien, E; Nagase, H; Soma, M | 1 |
Ahn, JS; Bode, AM; Choi, TW; Dong, Z; Erikson, RL; Huang, Z; Hwang, J; Jang, JH; Kim, BY; Lee, KW; Li, W; Liu, H; Liu, K; Ryoo, IJ; Thimmegowda, NR; Yang, Y; Zhou, X | 1 |
Ali, F; Hamiza, OO; Hasan, SK; Khan, AQ; Khan, R; Lateef, A; Rehman, MU; Sultana, S; Tahir, M | 1 |
Scott, G | 1 |
Hogg, N; McNeill, E | 1 |
Conney, AH; Khor, TO; Kong, AN; Lee, JH; Lu, YP; Shu, L; Su, ZY; Wu, TY; Zhang, C | 1 |
Abel, EL; Beltran, L; Bozeman, R; Cheng, T; DiGiovanni, J; Macias, E | 1 |
Cline, JM; Endo, Y; Fonseca, LL; Ji, J; Lorenzo, PS; Rajani, C; Ramos, JW; Sharma, A; Stone, JC; Yanagida, JK | 1 |
Chawsheen, HA; Colburn, NH; Gerard, M; Jiang, H; Mishra, M; Toledano, MB; Wei, Q; Wu, L; Young, MR | 1 |
Cipolat, S; Hoste, E; Natsuga, K; Quist, SR; Watt, FM | 1 |
Aoto, Y; Goitsuka, R; Hachiya, T; Hirose, S; Isogai, E; Katsuragi, Y; Kominami, R; Nakamura, T; Okumura, K; Saito, M; Sakakibara, Y; Wakabayashi, Y | 1 |
Artoni, E; Corsi, L; Gatti, AM; Sighinolfi, GL | 1 |
Hisanaga, A; Hou, DX; Ishida, H; Kumamoto, T; Sakao, K; Sogo, T; Terahara, N; Wada, K | 1 |
Celis, E; Condamine, T; Donthireddy, L; Gabrilovich, D; Knight, SC; Kumar, V; Lee, GH; Lenox, B; Luetteke, N; Malietzis, G; Martner, A; Mony, S; Moorghen, M; Ortiz, ML; Seykora, J | 1 |
Carr, TD; Feehan, RP; Hall, MN; Rüegg, MA; Shantz, LM | 1 |
Anders, J; Blumenberg, M; Cataisson, C; Efimova, T; Kiss, A; Koppel, AC; Yuspa, SH | 1 |
Heo, YS; Jang, YJ; Jung, SK; Kim, JE; Kim, JR; Lee, CC; Lee, CY; Lee, E; Lee, HJ; Lee, JH; Lee, KW; Lim, SS; Lim, TG; Seo, SG; Son, JE | 1 |
Bao, R; Bechill, J; Bindokas, VP; Faber, PW; Lingen, MW; Spiotto, MT; Zhong, R | 1 |
Abdul Hamid, R; Khaza'ai, H; Mohtarrudin, N; Saiful Yazan, L; Yeong, LT | 1 |
de Gruijl, F; Rebel, H; Tensen, K; van de Glind, G; van Kempen, M | 1 |
Bountra, C; Guo, Y; Kong, AN; Pung, D; Shu, L; Su, ZY; Wang, L; Yang, Y; Zhang, C | 1 |
Dai, X; Dang, Y; Gu, J; Liu, M; Liu, X; Ren, X; Wang, L; Xu, P; Ye, X | 1 |
Berx, G; Declercq, W; Denecker, G; Devos, M; Gilbert, B; Haigh, J; Hochepied, T; Lambert, J; Lemeire, K; Leurs, K; Libbrecht, L; Lippens, S; Mc Guire, C; Van Den Broecke, C; Vandenabeele, P; Vuylsteke, M | 1 |
Asai, M; Asai, N; Enomoto, A; Kato, T; Mii, S; Murakumo, Y; Nagino, M; Shiraki, Y; Sunagawa, M; Takahashi, M | 1 |
Cheng, PS; Chung, WC; Hu, CC; Lee, YJ; Tseng, TH; Wang, CJ | 1 |
Bode, AM; Dong, Z; Heo, YS; Kang, NJ; Lee, HJ; Lee, KW; Oh, SM; Pugliese, A; Rogozin, EA | 1 |
Bility, MT; Blazanin, N; Devlin-Durante, MK; Glick, AB; Gonzalez, FJ; Kang, BH; Kennett, MJ; Peters, JM; Ward, JM | 1 |
Hori, Y; Iigo, M; Imai, T; Kitahashi, T; Sugimura, T; Takahashi, M; Takasuka, N; Wakabayashi, K; Yoshimi, N | 1 |
Ashton, GH; Baldeschi, C; Brunton, VG; Canel, M; Doyle, B; Frame, MC; Green, TP; Mackintosh, LJ; Mason, SM; Sansom, OJ; Serrels, A; Serrels, B | 1 |
Cataisson, C; Hennings, H; Jay, S; Ohman, R; Patel, G; Pearson, A; Tsien, M; Wright, L; Yuspa, SH | 1 |
Bode, AM; Cho, YY; Dong, Z; Ericson, ME; Ma, WY; Yao, K; Zheng, D; Zhu, F | 1 |
Antonucci, L; Canettieri, G; Coni, S; Della Guardia, M; Di Magno, L; Giannini, G; Gulino, A; Nocerino, V; Screaton, R; Screpanti, I | 1 |
Barragan, DI; Charron, J; Dumesic, PA; Harada, K; Khavari, PA; Scholl, FA | 1 |
Colburn, NH; Hou, DX; Murakami, A; Nishizawa, T; Ohigashi, H; Tanaka, T; Yasuda, M | 1 |
Cheepala, SB; Clifford, JL; Cvek, U; Gill, JN; Kleiner, HE; Loganantharaj, R; Lynch, M; McMillian, A; Syed, Z; Trutschl, M; Yin, W | 1 |
Bode, AM; Cho, YY; Dong, Z; Malakhova, ML; Pugliese, A; Yao, K | 1 |
Boily, G; He, XH; Jardine, K; McBurney, MW; Pearce, B | 1 |
Dziadziuszko, H; Glosnicka, R; Graczyk, A; Jankowski, D; Jaskiewicz, K; Juzeniene, A; Kaliszewski, M; Kunikowska, D; Kwasny, M; Kwitniewski, M; Ma, LW; Moan, J; Peksa, R | 1 |
Bandyopadhyay, S; Chrisler, WB; Opresko, LK; Quesenberry, RD; Tan, R; Waters, KM; Weber, TJ | 1 |
Anagnostopoulos, I; Jöhrens, K; Moos, V; Schneider, T | 1 |
Adegboyega, P; Batra, V; Cheepala, SB; Clifford, JL; Digiovanni, J; Gill, JN; Kleiner, HE; Nathan, C; Stein, J; Syed, Z | 1 |
Kim, DH; Liu, D; Na, HK; Park, JM; Surh, YJ | 1 |
Glick, AB; Hogan, KA; Markell, LM; Pérez-Lorenzo, R; Yuspa, SH | 1 |
Hitomi, T; Tanaka, R; Tokuda, H; Wada, S | 1 |
Decicco-Skinner, KL; Lepage, PK; Simmons, JK; Trovato, EL; Wiest, JS | 1 |
Coste, I; Druillennec, S; Eychene, A; Hainaut, P; Hmitou, I; Kfoury, A; Le Corf, K; Lebecque, S; Renno, T | 1 |
Fukami, K; Hara, E; Hirao, A; Ishikawa, Y; Motoi, N; Ohtani, N; Sone, S; Tajima, T; Takahashi, A; Takeuchi, S; Yamakoshi, K; Yanagi, S; Yoshimoto, S | 1 |
Pardoll, DM; Wang, L; Yi, T; Yu, H; Zhang, W | 1 |
Ahn, SG; Choi, HK; Choi, HS; Khanal, P; Kwon, SM; Namgoong, GM; Oh, WK; Yun, HJ | 1 |
Chen, L; Qin, Z; Wang, C; Xiao, M; Zhang, J | 1 |
Chao, DC; Ho, TY; Hsiang, CY; Kao, ST; Li, CC; Liang, JA; Lin, LJ; Lo, HY; Wu, SL | 1 |
Chang, CS; Chao, DC; Ho, TY; Hsiang, CY; Huang, HC; Kao, ST; Liang, JA; Lin, LJ; Wu, SL | 1 |
Ahn, SG; Choi, HK; Choi, HS; Khanal, P; Namgoong, GM; Sohn, H; Yoon, JH | 1 |
Lee, SJ; Mar, W; Nam, KW | 1 |
Arai, T; Hamashima, Y; Hasegawa, J; Kajimoto, T; Node, M; Suzuki, N; Tanaka, R; Tokuda, H; Tsujii, H; Yamada, T | 1 |
Barker, JR; Becker Buscaglia, LE; Choudhury, SN; Kanakamedala, K; Kumar, M; Li, Y; Liu, MF; Ma, X | 1 |
Codarin, S; Huang, TT; Kevil, CG; Richardson, A; Robbins, D; Shen, X; Van Remmen, H; Wang, F; Wittwer, JA; Zhao, Y | 1 |
Brotman, JJ; Judd, NP; Lewis, JS; Pittman, ME; Schreiber, RD; Uppaluri, R; Winkler, AE | 1 |
Fukayama, M; Fukushima, N; Ishikawa, S; Kokudo, N; Shibahara, J; Shinozaki, A; Tanaka, M; Umeda, M | 1 |
Bhui, K; Chaturvedi, PK; George, J; Roy, P; Shukla, Y; Singh, M; Srivastava, AK | 1 |
Kim, SH; Li, Q; Lu, H; Lu, HJ; Lu, Q; Sambandam, SA; Thomson, A; Xin, Y | 1 |
Boudreau, NS; Cayer, ML; Heckman, CA; Varghese, M | 1 |
Arbeit, JM; Chung, CH; Day, R; Dong, Y; Grabowska, D; Humphrey, P; Kladney, RD; Lewis, J; Li, A; Michel, LS; Wang, J; Weber, JD; Zhang, K | 1 |
DaSilva, SC; Konger, RL; Kozman, AA; Martel, KC; Rezania, S; Sahu, RP; Travers, JB; Warren, SJ; Yao, Y | 1 |
Bohrman, JS; Fischer, SM; Gleason, GL; Hardin, LG; Slaga, TJ | 1 |
Akihisa, T; Fukatsu, M; Kikuchi, T; Kimura, Y; Motoi, T; Seki, A; Suzuki, N; Tokuda, H | 1 |
Akihisa, T; Huang, Y; Inafuku, K; Kikuchi, T; Miura, M; Motohashi, S; Suzuki, N; Suzuki, T; Tokuda, H; Zhang, J | 1 |
Chen, C; Huang, Y; Li, Y; Ruan, Z; Zhang, D | 1 |
Cotsarelis, G; Gordon, D; Li, S; Liu, Y; Morris, RJ; Park, H; Trempus, CS | 1 |
Ai, W; Huang, S; Li, J; Liu, C; Wang, TC; Yu, F; Yu, T; Zheng, H | 1 |
Gong, JN; Luo, ZM; Shen, C; Tan, ZQ; Wang, F; Wang, XS; Yang, GH; Yin, XL; Yu, J; Zhang, JW; Zhang, XH | 1 |
Chae, JI; Cho, JH; Cho, MK; Kim, DJ; Lee, KA; Lee, SH; Nam, HS; Shim, JH; Woo, KM | 1 |
Eilers, M; Elsässer, HP; Hönnemann, J; Sanz-Moreno, A; Wolf, E | 1 |
Cho, YS; Cho, YY; Kim, DJ; Lee, KA; Lee, SH; Lee, YJ; Park, SY; Shim, JH; Woo, KM | 1 |
Adegboyega, P; Batra, V; Clifford, JL; Coburn, MA; DiGiovanni, J; Gill, JN; Kleiner-Hancock, HE; Mathis, JM; Shi, R; Syed, Z | 1 |
Alameda, JP; Bravo, A; Casanova, ML; Dupuy, AJ; Navarro, M; Page, A; Quintana, RM; Ramírez, A; Sánchez-Viera, M | 1 |
Clarke, M; Das, S; Huels, D; Jamieson, T; Jung, A; Neumann, J; Nibbs, RJ; Olson, MF; Samuel, MS; Sansom, OJ; Steele, CW | 1 |
Bonsignore, L; Drexler, SK; Gross, O; Hermeking, H; Jackstadt, R; Masin, M; Schneider, P; Tardivel, A; Tschopp, J; Yazdi, AS | 1 |
Belloli, S; Beltrami, E; Fassina, A; Fazio, F; Giorgio, M; Marcu, R; Moresco, R; Pelicci, P; Valtorta, S | 1 |
Li, W; Zhao, Y | 1 |
Chen, HD; He, CD; Liu, CH; Lu, T; Ma, GZ; Qiao, J; Wei, B; Wei, HC | 1 |
Jung, BG; Lee, BJ; Lee, JA | 1 |
Cho, NP; Cho, SD; Choi, ES; Li, C; Shin, JA | 1 |
Li, W; Liu, J; Zhao, Y | 1 |
Cheng, KH; Chiou, YS; Ho, CT; Pan, MH; Sang, S; Wang, YJ | 1 |
Anagnostopoulos, I; Bommert, K; Dörken, B; Hinz, M; Jundt, F; Krappmann, D; Lietz, A; Mathas, S; Mechta-Grigoriou, F; Scheidereit, C; Stein, H | 1 |
Conti, CJ; Kiyokawa, H; LaCava, M; Miliani de Marval, PL; Moons, DS; Rodriguez-Puebla, ML | 1 |
Brown, EM; Chattopadhyay, N; Tfelt-Hansen, J | 1 |
Chen, YC; Hou, WC; Ko, CH; Lee, WR; Lin, HY; Shen, SC; Yang, LL | 1 |
Black, EJ; Clark, W; Gillespie, DA; MacLaren, A; Walker, M | 1 |
Bortner, CD; Cannon, RE; Tennant, RW; Trempus, CS; Wei, SJ | 1 |
Bode, AM; Dong, Z; Liu, G; Ma, WY; Zhang, Y | 1 |
Grenman, R; Hieta, N; Impola, U; Jahkola, T; Jeskanen, L; Kähäri, VM; Saarialho-Kere, U; Suomela, S; Toriseva, M | 1 |
Fujii, M; Hou, DX; Li, JJ; Lin, S | 1 |
Aoki, M; Aronheim, A; Blazek, E; Kruse, U; Vogt, PK; Wasmer, S | 1 |
Kupper, TS; Morales, RE; Murphy, JE; Scott, J | 1 |
Wölfle, D | 1 |
Cao, M; Chang, PL; Hicks, P | 1 |
Colburn, N; Fujii, M; Hou, DX; Kai, K; Li, JJ; Lin, S; Terahara, N; Wakamatsu, M; Young, MR | 1 |
Bowden, GT; Chen, QM; Dilley, TK | 1 |
Albor, A; Babcock, M; Bowden, GT; El-Hizawi, S; Hennings, H; Horn, EJ; Kulesz-Martin, M; Liu, Y; Lozano, G; Vanderbeek, GE; Weinberg, WC | 1 |
Ali, RC; Hansen, LA; Tennant, RW; Trempus, CS; Wei, SJ | 1 |
Aronheim, A; Ben-Izhak, O; Heinrich, R; Livne, E | 1 |
Bowman, L; Castranova, V; Ding, M; Huang, C; Leonard, S; Lu, Y; Shi, X; Vallyathan, V; Wang, L | 1 |
Bernstein, LR; Samuel, S | 1 |
Chen, TJ; Chen, YC; Chien, LL; Lin, HY; Shen, SC | 1 |
Brindley, JM; Citro, ML; Colburn, NH; Dhar, A; Keefer, LK; Stark, C | 1 |
Hedley, D; Karasarides, M; Marais, R; Martin, J; Niculescu-Duvaz, D; Ogilvie, L; Springer, CJ; Wellbrock, C | 1 |
Colburn, NH; Dhar, A; Hu, J; Reeves, R; Resar, LM | 1 |
Barnes, J; Boudreau, N; Cayer, M; Hall, C; Heckman, CA; Kozma, R; Li, Y; Lim, L; Plummer, HK; Urban, JM | 1 |
Bode, AM; Cho, YY; Choi, BY; Choi, HS; Dong, Z; Mizuno, H | 1 |
Chimeno Zoth, SA; Collet, AM; Heber, E; Itoiz, ME; Schwint, AE | 1 |
Jahnen-Dechent, W; King, LE; Leite-Browning, ML; Matrisian, LM; McCawley, LJ; Ochieng, J | 1 |
Fisher, PB; Laskin, JD; Mufson, RA; Weinstein, IB | 1 |
Cao, ZY; Du, HJ; Liao, QP; Sun, YT; Zeng, Y; Zhao, J | 1 |
Chignell, CF; He, YY; Huang, JL | 1 |
Fujii, M; Hou, DX; Komine, S; Rabah, IO | 1 |
Benavides, F; Fischer, SM; Kim, E; Newman, RA; Rundhaug, JE; Yang, P | 1 |
Bowman, LL; Castranova, V; Ding, M; Feng, R; Jiang, BH; Leonard, SS; Lu, Y; Shi, X; Vallyathan, V | 1 |
Bai, Y; Edamatsu, H; Kataoka, T; Maeda, S; Saito, H; Satoh, T; Suzuki, N | 1 |
Blasco, MA; Cayuela, ML; Flores, JM | 1 |
Aplan, PD; Lin, YW; Slape, C; Zhang, Z | 1 |
Ao, L; Cao, J; Huang, MH; Liu, JY; Wu, YZ; Yang, MS; Zeng, ZX; Zhang, YQ | 1 |
Fischer, SM; He, G; Lubet, RA; Muga, S; Thuillier, P | 1 |
Bowman, LL; Castranova, V; Ding, M; Feng, R; Lu, Y; Qian, Y | 1 |
Adamson, ED; English, C; Krones-Herzig, A; Liang, H; Mercola, D; Mittal, S; Soni, T; Urcis, R; Yule, K | 1 |
Angel, P; Breitenbach, U; Fürstenberger, G; Gebhardt, C; Hess, J; Mauch, C; Richter, KH | 1 |
Liu, GT; Sun, H | 2 |
Beguinot, F; Formisano, P; Libertini, S; Miele, C; Oriente, F; Perruolo, G; Portella, G; Raciti, GA; Santopietro, S; Troncone, G | 1 |
Aoki, I; Colledge, WH; Foidart, JM; Hata, R; Kato, Y; Koshika, S; Kubota, Y; Nagashima, Y; Sakai, N; Thompson, EW; Tsukuda, M; Yao, M | 1 |
Hayashi, M; Kinae, N; Masuda, S; Mizuhashi, F; Nagai, M; Nakajima, M; Shimada, S; Sugiyama, C | 1 |
Furuya, T; Inomata, K; Kawauchi, S; Oga, A; Sasaki, K | 1 |
Fischer, SM; He, G; Sung, YM | 1 |
Araki, H; Asakura, M; Asasda, S; Baba, H; Fushiwaki, Y; Hamada, S; Kitou, N; Nakamura, T; Nakamura, Y; Ohmori, K; Oishi, H; Sakai, A; Sasaki, K; Sasaki, S; Shimada, S; Takagi, H; Tanaka, N; Tsuchiya, T; Umeda, M; Uno, Y; Washizuka, M; Yajima, S; Yamamoto, Y; Yamamura, E; Yatsushiro, T; Yoshimura, I | 1 |
Alexander, CL; Greenhalgh, DA; Porter, MJ; Quinn, JA; Wu, H; Yao, D | 1 |
Bai, Z; Cheng, B; He, P; Ke, L; Yu, Q | 1 |
Chen, Z; Hicks, J; Honeycutt, KA; Koster, MI; Miers, M; Nuchtern, J; Roop, DR; Shohet, JM | 1 |
Davies, R; Edwards, RE; Gant, TW; Greaves, P; Ridd, K; Smith, AG; Wolfreys, A; Zhang, SD | 1 |
Chen, YC; Chien, LL; Lee, HM; Lin, CW; Shen, SC | 1 |
Bakthavatchalu, V; Chaiswing, L; Oberley, TD; St Clair, DK; Zhao, Y | 1 |
Cameron-Smith, D; Carey, KA; Collier, GR; Klein, R; Sanigorski, A; Segal, D; Walder, K | 1 |
Aguilar-Quesada, R; García Del Moral, R; Martin-Oliva, D; Martínez-Romero, R; Muñoz-Gámez, JA; O'valle, F; Oliver, FJ; Piris, MA; Ruiz de Almodóvar, JM; Villuendas, R | 1 |
Bode, AM; Cho, YY; Dong, Z; He, Z; Mizuno, H; Seok Choi, H; Tatsumi, Y | 1 |
Denning, MF; Gerber, L; Gilliam, AC; Guo, H; Miao, H; Singh, J; Wang, B | 1 |
Beard, P; Chambon, P; Dubey, C; Dubois, N; Essers, MA; Hummler, E; Metzger, D; Offner, S; Oskarsson, T; Roger, C; Trumpp, A | 1 |
Chan, EL; Collins, MH; Kader, SA; Pathrose, P; Peace, BE; Toney, K; Waltz, SE | 1 |
Choi, HG; Kim, JA; Kim, SJ; Lee, ES; Lee, YS; Paek, SH; Park, BC; Yong, CS | 1 |
Castranova, V; Kisin, ER; Kommineni, C; Murray, AR; Shvedova, AA; Vallyathan, V | 1 |
Antal, MC; Castaneda, E; Chambon, P; Desvergne, B; Gariglio, P; Indra, AK; Jiang, M; Kato, S; Loehr, CV; Meng, X; Messaddeq, N; Metzger, D; Wahli, W | 1 |
Hur, HJ; Kwon, JY; Lee, HJ; Lee, KW | 1 |
Niemann, C; Owens, DM; Schettina, P; Watt, FM | 1 |
Gu, Q; Sun, Y; Tan, M | 1 |
Chen, TT; Gao, J; Pan, LL; Sun, L; Yuan, LX; Zhou, CY; Zhu, YP | 1 |
Bae, DS; Darwiche, N; Glick, AB; Hennings, H; Perez-Lorenzo, R; Ryscavage, A; Wright, L; Yuspa, SH | 1 |
Chiu, RJ; Meyskens, FL; Misner, BJ; Yang, S | 1 |
Fischer, SM; Kim, E; Pavone, A; Rundhaug, JE | 1 |
Horie, S; Katsuki, M; Muto, S | 1 |
Bode, AM; Bowden, GT; Cho, YY; Dong, Z; Kang, NJ; Kim, HG; Lee, HJ; Lee, KW; Rogozin, EA; Surh, YJ | 1 |
Andrée, B; Bylaite, M; Kellermann, S; Kloepper, JE; Paus, R; Reifenberger, J; Rüther, U; Ruzicka, T; Walz, M | 1 |
Bower, KA; Chen, G; Ding, M; Gao, TW; Gao, Y; Ke, Z; Luo, J; Ma, C; Odetallah, M; Wang, J | 1 |
Abel, E; Beltran, L; Carbajal, S; Chan, KS; Clifford, J; Digiovanni, J; Kataoka, K; Peavey, M; Sano, S; Shen, J | 1 |
Bode, AM; Cho, YY; Dong, Z; Kang, BS; Kim, HG; Yao, K; Zheng, D | 1 |
Bowden, GT; Gu, Q; Normolle, D; Sun, Y | 1 |
Dai, C; Lindquist, S; Rogers, AB; Whitesell, L | 1 |
Kim, Y; Klein-Szanto, A; Macias, E; Miliani de Marval, PL; Rodriguez-Puebla, ML | 1 |
Hara-Chikuma, M; Verkman, AS | 1 |
Chiappetta, G; Costinean, S; Croce, CM; De Martino, I; Fedele, M; Fusco, A; Iuliano, R; Kusewitt, DF; Oberyszyn, TM; Palmieri, D; Server, IN; Visone, R | 1 |
Gao, J; Huang, C; Li, J; Ouyang, W; Song, L; Zhang, D | 1 |
Bode, AM; Bowden, GT; Dong, Z; Heo, YS; Hwang, MK; Kang, NJ; Lee, HJ; Lee, KW; Pugliese, A; Rogozin, EA | 1 |
Baker, AR; Colburn, NH; Hagan, JP; Hegamyer, G; Jansen, AP; Schmid, T | 1 |
Choi, HK; Choi, HS; Ermakova, SP; Kusaykin, MI; Lee, NY; Shevchenko, NM; Zvyagintseva, TN | 1 |
Arlt, VM; Baird, WM; Bildfell, R; Courter, LA; Fischer, K; Luch, A; Musafia-Jeknic, T; Pereira, C; Phillips, DH; Poirier, MC | 1 |
Bode, AM; Cho, YY; Dong, Z; Kang, NJ; Kim, HG; Lee, KW; Oh, SM | 1 |
Krishnan, R; Maru, G; Patel, R; Ramchandani, A | 1 |
Carbajal, S; Clifford, JL; DiGiovanni, J; Kataoka, K; Kim, DJ | 1 |
Beltran, L; Carbajal, S; Digiovanni, J; Hursting, SD; Leroith, D; Moore, T; Perkins, SN; Yakar, S | 1 |
Guo, QN; Li, Y; Meng, G | 1 |
Fujita, J; Sugawara, K; Tokuda, H; Yoshida, O | 1 |
Deegan, MJ; Maeda, K | 1 |
Hirakawa, T; Kakunaga, T; Shimomura, K; Sugimura, T | 1 |
Arcoleo, J; Backer, J; Gattoni-Celli, S; Hsiao, WL; Jeffrey, A; Kirschmeier, P; Okin, E; Weinstein, IB | 1 |
Dorsch-Häsler, K; Fisher, PB; Ginsberg, HS; Weinstein, IB | 1 |
Hennings, H; Kulesz-Martin, M; Lichti, U; Yuspa, SH | 1 |
Kaufman, DG; Siegfried, JM | 1 |
Ben, T; Lichti, U; Yuspa, SH | 1 |
Andreotti, PE | 1 |
Borek, C; Troll, W | 1 |
Emmerson, A; Grabham, P; Parkinson, EK | 1 |
Kakinuma, K; Kitagawa, S; Miura, Y; Nojiri, H; Ohta, M; Saito, M; Takaku, F | 1 |
Emmerson, A; Parkinson, EK | 1 |
Emmerson, A; Gorman, PA; Parkinson, EK; Pera, MF | 1 |
Antecol, MH; Mukherjee, BB | 1 |
Bollum, FJ; Breviario, D; LeBien, TV; Sacchi, N; Trost, S | 1 |
Leister, KJ; Tomei, LD; Wenner, CE | 1 |
Fisher, PB; Lee, LS; Weinstein, IB | 1 |
Seif, R | 1 |
Borek, C; Geard, CR; Guernsey, D; Mason, H; Miller, RC; Ong, A; Osmak, RS; Rutledge-Freeman, M | 1 |
Colburn, NH; Gindhart, TD | 1 |
Weinstein, IB | 3 |
Hemstad, J; Rivedal, E; Sanner, T | 1 |
Chechik, BE; Gelfand, EW; Letarte, M; Mak, TW; Nagasawa, K; Sengupta, S | 1 |
DiPaolo, JA; Evans, CH | 1 |
August, JT; Skubitz, KM; Zhen, YS | 1 |
De Larco, JE; Shoyab, M; Todaro, GJ | 1 |
Bockman, RS; Honn, KV; Marnett, LJ | 1 |
Rivedal, E | 2 |
Davies, C; Rivedal, E; Sanner, T | 1 |
Georg-Fries, B; Mueller-Lantzsch, N | 1 |
Rivedal, E; Sanner, T | 3 |
Abutbul, H; Rotter, V; Wolf, D | 1 |
Borek, C | 1 |
Herschman, HR | 1 |
Poulin, L; Wainberg, MA | 1 |
Abe, E; Chida, K; Kuroki, T; Sasaki, K; Suda, T | 1 |
Iyer, N; King, L; Krebs, C; Kucera, LS; Waite, BM | 1 |
Billing, R; Bohman, R; Koeffler, HP; Ranyard, J; Yelton, L | 1 |
Haugen, A; Lechner, JF; McClendon, IA; Tokiwa, T | 1 |
Nagasawa, K | 1 |
Dokhelar, MC; Fradelizi, D; Harel, A; Tursz, T; Wakasugi, H | 1 |
Colburn, NH; Gindhart, TD; Lerman, MI; Nakamura, Y; Srinivas, L | 1 |
Borek, C; Cleaver, JE; Fujiki, H | 1 |
Yuspa, SH | 2 |
Butler, AP; Slaga, TJ | 1 |
DiPaolo, JA; Evans, CH; Greiner, JW | 1 |
Dederer, E; Goerttler, K; Hesse, B; Loehrke, H; Rosenkranz, G; Schweizer, J | 1 |
Liu, CK; Qian, GX; Rosen, A; Schmied, R; Schreiber, C; Waxman, S | 1 |
Harris, CC; Lechner, JF; Ozanne, C; Saladino, AJ; Willey, JC | 1 |
Cerutti, P; Zimmerman, R | 1 |
Carter, C; Dehazya, P; Gilmore, T; Martin, GS; Moss, P; Radke, K | 1 |
Blenis, J; Hawkes, SP | 1 |
Fürstenberger, G; Goerttler, K; Kinzel, V; Loehrke, H; Marks, F | 1 |
Gattoni-Celli, S; Hsiao, WL; Weinstein, IB | 1 |
Chou, TC; Kopelovich, L | 1 |
Barrett, JC; Gray, TE; Mass, MJ; Nettesheim, P; Steele, VE | 1 |
Fürstenberger, G; Marks, F | 3 |
Baumbach, L; Sydow, G; Wunderlich, V | 1 |
Gelfand, EW; Letarte, M; Okamura, J; Sigal, NH; Stein, LD | 1 |
Borek, C; Geard, CR; Guernsey, DL; Miller, RC; Smith, JE | 1 |
Copley, MP; Gindhart, TD; Stevens, L | 1 |
Cerni, C | 2 |
Gainer, HS; Kinsella, AR; Schor, S | 1 |
Kennedy, AR; Little, JB; Troll, W | 1 |
Kennedy, AR; Radner, BS | 1 |
Cohen, M; Colburn, NH; Dion, LD; Gindhart, TD; Hegamyer, GA; Srinivas, L; Wendel, EJ | 1 |
Bertram, JS; Hui, SW; Mordan, LJ | 1 |
Blaese, RM; Decker, JM; Hall, RE; Muchmore, AV | 1 |
Price, BJ; Whittington, K; Zucker, RM | 1 |
Kornatowski, G; Kumar, SA; O'Connor, D; Walsh, J; Yourno, J | 1 |
Aman, P; Biberfeld, P; Gordon, J; Klein, G; Mellstedt, H | 1 |
Grotendorst, GR | 1 |
DeMarinis, AJ; DiPaolo, JA; Doniger, J; Evans, CH | 3 |
Colburn, NH; Srinivas, L | 2 |
Dutton, RW; Swain, SL; Wetzel, GD | 1 |
Brodie, RA; Gans, PJ; Larsen, NE; McCarroll, LA; Sullivan, R | 1 |
Kadin, ME; Nasu, K; Sako, D; Su, IJ | 1 |
DiPaolo, JA | 2 |
Fusenig, NE | 1 |
Colburn, NH; Gindhart, TD; Talmadge, CB | 2 |
Gainer, HS; Kinsella, AR | 1 |
Abernethy, DJ; Boreiko, CJ; Frazelle, JH | 2 |
Alitalo, K; Hautanen, A; Keski-Oja, J; Rapp, UR | 1 |
Kokunai, T; Matsumoto, S; Tamaki, N; Taomoto, K | 1 |
Kopelovich, L | 4 |
Enaka, K; Ono, T; Umeda, M | 1 |
Kennedy, AR; Long, SD; Quigley, JP; Troll, W | 1 |
Fisher, PB; Fujiki, H; Miranda, AF; Mufson, RA; Sugimura, T; Weinstein, IB; Weinstein, LS | 1 |
Abernethy, DJ; Boreiko, CJ; Frazelle, JH; Ragan, DL | 1 |
Sugimura, T | 1 |
Wigley, CB | 1 |
Colburn, N; Copley, M; Gindhart, T | 1 |
Fjose, A; Kleppe, K; Lillehaug, JR; Pryme, IF | 1 |
Nettesheim, P; Steele, V; Vanderlaan, M | 1 |
Ben, T; Hennings, H; Kulesz-Martin, M; Yuspa, SH | 1 |
Bradley, MO; Diamond, L; O'Brien, TG; Sina, JF | 1 |
Mahlum, DD; Springer, DL; Swanger, D | 1 |
Belman, S | 1 |
Boreiko, CJ; Butterworth, BE; Dorman, BH | 1 |
Abrahm, J; Cooper, RA; Lange, B; Levis, A; Meo, P; Pegoraro, L; Rovera, G | 1 |
Cooper, RA; Ip, SH | 1 |
Cassileth, PA; Cooper, RA; Suholet, D | 1 |
Abruzzo, G; Ben, T; Colburn, NH; Jardini, E; Lichti, U; Ozanne, S; Wendel, E; Yuspa, SH | 1 |
Ben, T; Hennings, H; Lichti, U; Yuspa, SH | 1 |
Ip, SH; Lebman, D; Perussia, B; Rovera, G; Trinchieri, G | 1 |
Abruzzo, G; Colburn, NH; Wendel, EJ | 1 |
Bussolino, F; Camussi, G; Ghezzo, F; Pegoraro, L | 1 |
Bosmann, HB; Miska, D | 1 |
Colburn, NH; Gindhart, TD; Srinivas, L | 2 |
Bateman, J; Bear, J; Colburn, NH; De Luca, LM; Dion, LD | 1 |
Brown, G; Bunce, CM; Michell, RH; Stone, PC; Toksoz, D | 1 |
Carchman, RA; Laskin, DL; Laskin, JD; Weinstein, IB | 1 |
Hoffman-Liebermann, B; Liebermann, D; Sachs, L | 1 |
Ashman, RF; Billing, R; Chan, G; Golde, DW; Lusis, AJ; Weisbart, RH | 1 |
Kennedy, AR; Little, JB | 2 |
De Luca, LM; Jetten, AM | 1 |
Evans, CH; Ransom, JH | 1 |
Halper, JP; Pernis, B; Roth, P; Weinstein, IB | 1 |
Bonnard, GD; Fruehauf, JP; Herberman, RB | 1 |
Croop, J; Dlugosz, AA; Holtzer, H; Toyama, Y | 1 |
Blumberg, PM | 2 |
Friedman, EA | 1 |
Cherington, PV; Medrano, EE; Pardee, AB | 1 |
Bollum, FJ; Kersey, JH; LeBien, TW; Yasmineh, WG | 1 |
Dzarlieva, RT; Fusenig, NE | 1 |
Chang, C; Trosko, JE; Tsushimoto, G; Warren, ST; Yotti, LP | 1 |
Sachs, L; Symonds, G | 1 |
Sivak, A | 1 |
Elkind, MM; Han, A | 1 |
Diamond, L; O'Brien, TG; Saladik, D | 2 |
Kinzel, V; Krombholz-Nolinski, I; Richards, J; Stöhr, M | 1 |
Cockle, SM; Dean, RT | 1 |
Colburn, NH; Dion, LD; Wendel, EJ | 1 |
DiPaolo, JA; Doniger, JN; Evans, CH; Popescu, NC | 1 |
Argyris, TS | 1 |
Bergin, LM; Bertram, JS; Budnick, JE; Meegan, RR; Mordan, LJ | 1 |
Backer, JM; Boersig, MR; Weinstein, IB | 1 |
Cooper, PD; Marshall, SA; Masinello, GR | 1 |
Albino, AP; Cairncross, JG; Eisinger, M; Houghton, AN; Old, LJ | 1 |
Bias, NE; Kopelovich, L | 1 |
Claisse, PJ; Hince, TA; Roscoe, JP; Winslow, DP | 1 |
Sivak, A; Tu, AS | 1 |
Fisher, PB; Weinstein, IB | 1 |
Hennings, H; Lichti, U; Morgan, D; Yuspa, SH | 1 |
Marchok, AC; Nettesheim, P; Steele, VE | 2 |
Boreiko, CJ; Ragan, DL | 1 |
Hennings, H; Lichti, U; Yuspa, SH | 1 |
Arnstein, P; Huebner, RJ; Rhim, JS | 1 |
Marsh, WH; Parsa, I; Sutton, AL | 1 |
Kennedy, AR; Little, JB; Murphy, G | 1 |
Bärlin, E; Gemsa, D; Grimm, W; Kramer, W; Leser, HG | 1 |
Borek, C; Geard, CR; Harisiadis, L; Mason, H; Miller, RC; Napholz, A; Ong, A; Osmak, RS; Perez, N; Rutledge-Freeman, M | 1 |
Hayashi, M; Honma, M; Mizusawa, H; Ohno, T; Sasaki, K; Sofuni, T; Tanaka, N | 1 |
Eckhardt, JN; Greenhalgh, DA; Roop, DR; Wang, XJ | 1 |
Chang, RL; Conney, AH; Fisher, C; Huang, MT; Lu, YP; Ma, W; Manchand, PS; Newmark, HL | 1 |
Owens, DM; Smart, RC; Spalding, JW; Tennant, RW | 1 |
Biaglow, J; Kennedy, SH; Manevich, Y | 1 |
Tsuchiya, T; Umeda, M | 2 |
Kennedy, AR | 2 |
Garrido, C; Gospodarowicz, D; Li, RP; Samarut, J; Saule, S | 1 |
Albino, AP; Dosik, JS; Loganzo, F; Nanus, DM; Sudol, M; Vidal, MJ; Zhao, Y | 1 |
Miyata, N; Sakai, A; Takahashi, A | 2 |
Ip, C; Scimeca, JA; Thompson, HJ | 1 |
Rubin, AL | 1 |
Ben-Ari, ET; Bernstein, LR; Birrer, MJ; Colburn, NH; Watts, RG; Wendel, E; Winterstein, D | 1 |
Mukherjee, AB; Mukherjee, BB; Su, L | 1 |
Chang, PL; Prince, CW; Yang, WC | 1 |
Aloj, SM; Bifulco, M; Laezza, C; Perillo, B; Romano, A; Santillo, M; Tedesco, I | 1 |
Qiu, SL; Wang, ML; Wu, J; Xu, Z; Zhu, DX; Zhu, JQ | 1 |
Fürstenberger, G; Marks, F; Müller-Decker, K; Scholz, K | 1 |
Asano, Y; Enomoto, T | 2 |
Bessi, H; Nguyen-Ba, G; Rast, C; Rether, B; Vasseur, P | 1 |
Kennedy, AR; Krinsky, NI | 1 |
Dertinger, SD; Tometsko, AM; Torous, DK | 1 |
Cao, J; Elkind, MM; He, L; Wells, RL; Xing, Y | 1 |
Cmarik, JL; Colburn, NH; Herschman, H | 1 |
Boukamp, P; Fitzgerald, DJ; Fusenig, NE; Mesnil, M; Piccoli, C; Yamasaki, H | 1 |
Israel, L; Mainguene, C; Nehme, A; Planchon, P; Prevost, G; Salle, V; Spanakis, E; Starzec, AB; Valette, A; Veber, N | 1 |
Cecchi, C; Mapelli, E; Sanfilippo, O; Supino, R | 1 |
Chang, RL; Conney, AH; Huang, MT; Lou, YR; Lu, YP; Newmark, HL; Reuhl, KR | 1 |
Elkind, MM | 1 |
Guo, CY; Han, R | 1 |
Haliday, E; Hirst, M; Lou, L; Nakamura, J | 1 |
Coppock, DL; Nathanson, L | 1 |
Hall, EJ; Hei, TK; Piao, CQ; Thomas, S; Willey, JC | 1 |
Rubin, AL; Rubin, H | 1 |
Cmarik, JL; Colburn, NH; Dong, Z; Wendel, EJ | 1 |
Bhisey, RA; Borges, AM; Ramchandani, AG | 1 |
Frampton, J; Graf, T; Kraut, N; McNagny, KM | 1 |
Birrer, MJ; Colburn, NH; Dong, Z; Matrisian, LM; Watts, RG | 1 |
Lipsick, JS; Smarda, J | 1 |
Borek, C; Merrill, AH | 1 |
Arita, Y; O'Driscoll, KR; Weinstein, IB | 1 |
Finkenzeller, G; Heidecker, G; Hummel, R; Kochs, G; Kolch, W; Marmé, D; Mischak, H; Rapp, UR; Vahidi, H | 1 |
Cacace, AM; Fabbro, D; Guadagno, SN; Krauss, RS; Weinstein, IB | 1 |
Brückner, A; Tony, HP; Wilhelm, M | 1 |
Honda, I; Nishi, Y; Semba, M; Shibagaki, M | 1 |
Garrett, LR; McDougall, JK; Perez-Reyes, N; Smith, PP | 1 |
Rivedal, E; Roseng, LE | 1 |
Bols, BL; Gillis, KC; Lohman, PH; Naaktgeboren, JM; Niericker, M; Simons, JW | 1 |
Bishop, JM; McMahon, M; Samuels, ML; Weber, MJ | 1 |
Bassin, RH; Heidecker, G; Kolch, W; Rapp, UR; Troppmair, J; Yanagihara, K | 1 |
Autrup, H; Christensen, B; Kieler, J; Skouv, J | 1 |
Mikalsen, SO; Sanner, T | 1 |
Harris, PE; Hong, B; Lupu, F; Reed, EF; Suciu-Foca, N | 1 |
Atherton, GT; Bianchi, SM; Deed, RW; Johnston, D; Murphy, JJ; Norton, JD; Santibanez-Koref, M | 1 |
Blackshear, PJ; Macara, IG; Stumpo, DJ; Wojtaszek, PA | 1 |
Blumberg, PM; Goodnight, JA; Kazanietz, MG; Kolch, W; Martiny-Baron, G; Mischak, H; Mushinski, JF; Pierce, JH; Schaechtle, C | 1 |
Alani, R; Birrer, MJ; Brown, PH; Preis, LH; Szabo, E | 1 |
Ackland-Berglund, CE; Cuchens, MA; Garrett, LR; Jones, CJ | 1 |
Chang, PL; Prince, CW | 1 |
Craig, RW; Guggino, WB; Lu, L; Markakis, D; Yang, T | 1 |
Adey, WR; Cain, CD; Thomas, DL | 2 |
Arbeit, JM; Ayer, DE; Eisenman, RN; Foley, KP; Hanahan, D; Hurlin, PJ | 1 |
Engelmann, H; Hess, S | 1 |
Dusinská, M; Kolman, A | 1 |
Colburn, NH; Dawson, MI; Dong, Z; Li, JJ | 1 |
Hakomori, S; Igarashi, Y; Masamune, A; Ohta, H; Sakakura, C; Shirahama, T; Sweeney, EA | 1 |
Colacci, A; Da Vià, C; Grilli, S; Horn, W; Manzini, E; Perocco, P; Silingardi, P; Vaccari, M | 1 |
Herlyn, M; Montone, KT; Nesbit, M; Satyamoorthy, K; Soballe, PW | 1 |
Folini, M; Lin, HC; Mischak, H; Perletti, GP; Piccinini, F; Tashjian, AH | 1 |
Harms-Ringdahl, M; Kolman, A | 1 |
Marquardt, H; Wölfle, D | 1 |
Colburn, N; Dong, Z; Lavrovsky, V; Ma, WY | 1 |
Degawa, H; Nakamura, A; Nakaoka, R; Tsuchiya, T | 1 |
George, K; Kampherstein, JA; Laughlin, KV; Mullin, JM; O'Brien, TG; Russo, LM; Saladik, DT; Shurina, RD; Soler, AP | 1 |
Donehower, LA; Greenhalgh, DA; Roop, DR; Wang, XJ | 1 |
Isfort, RJ; Kerckaert, GA; LeBoeuf, RA | 1 |
Agarwal, R; Ahmad, N; Mohan, RR; Mukhtar, H | 1 |
Cano, A; Conti, CJ; Duran, H; Jorcano, JL; Larcher, F; Murillas, R; Quintanilla, M; Robles, AI | 1 |
Cacace, AM; Han, EK; Kolch, W; Philipp, A; Ueffing, M; Weinstein, IB | 1 |
Caldeira, AA; Parfett, CL; Pilon, R | 1 |
Dong, Z; Huang, C; Ma, WY; Schmid, HH; Schmid, PC | 1 |
Amstad, PA; Berezesky, IK; Ichimiya, M; Liu, H; Trump, BF | 1 |
Brown, RE; Dong, Z; Huang, C; Ma, WY | 1 |
Baldi, A; Mladovan, AG; Shayo, CC | 1 |
Foster, DA; Hornia, A; Jiang, YW; Lu, Z; Ohno, S; Zang, Q | 1 |
Chen, Z; He, Z; Shao, X; Yao, K | 1 |
Colburn, NH; Dong, Z; Strickland, J; Sun, Y | 1 |
Dorsman, JC; Israël, A; Schouten, GJ; Toebes, M; van der Eb, AJ; Vertegaal, AC; Whiteside, ST; Zantema, A | 1 |
Dong, Z; Hecht, SS; Huang, C; Ma, WY | 1 |
Chen, G; Colburn, NH; Saffer, JD; Thurston, SJ | 1 |
Colburn, NH; Crawford, HC; Dong, Z; Lavrovsky, V; Matrisian, LM; Taub, D; Watts, R | 1 |
Hamano, T; Konoshima, T; Takasaki, M; Tokuda, H; Yasuda, I | 1 |
Benehacene, A; Kamps, M; Scheele, JS; White, FC | 1 |
Colburn, NH; Ghosh, P; Li, JJ; Westergaard, C | 1 |
Lee, SF; Lin, JK | 1 |
Ji, ZW; Li, BM; Liu, ZS; Zeng, Y | 1 |
Fischer, SM; Li-Stiles, B; Lo, HH | 1 |
Dong, Z; Huang, C; Ma, W; Yang, CS | 1 |
Chang, PL; Garretson, K; Lee, TF; Prince, CW | 1 |
Amstad, PA; Berezesky, IK; Chang, S; Ichimiya, M; Liu, H; Trump, BF | 1 |
Gong, Y; Shou, J; Wu, D | 1 |
Chen, ZH; Gopalakrishna, R; Gundimeda, U | 1 |
Kaneko, T; Miyazaki, K; Moriyama, K; Okubo, T; Sakamoto, Y; Shoji, A; Tsuchiya, T; Umeda, M | 1 |
Linder, S; Ljungdahl, S; Shoshan, MC; Sollerbrant, K; Svensson, C | 1 |
Colburn, N; Dong, Z; Huang, C; Ma, WY; Young, MR | 1 |
Gschwendt, M; Kittstein, W; Krammer, PH; Möller, P; Sträter, J; von Reyher, U | 1 |
Acs, P; Blumberg, PM; Goodnight, J; Mischak, H; Mushinski, JF; Wang, QJ | 1 |
Bessi, H; Cruciani, V; Dhalluin, S; Elias, Z; Gate, L; Nguyen-Ba, G; Pages, N; Poirot, O; Rast, C; Tapiero, H; Vasseur, P | 1 |
Aiba, S; Tagami, H | 1 |
Darwiche, N; De Luca, LM; Gartsbein, M; Hansen, L; Hennings, H; Lowry, D; Morgan, DL; Tennenbaum, T; Yuspa, SH | 1 |
Cacace, AM; Han, EK; Marmè, D; Ueffing, M; Weinstein, IB | 1 |
Buddenbaum, W; Elkind, MM; Hill, CK; Hu, Q; Wells, RL; Xing, Y | 1 |
Lavrovskiĭ, VA; Subkhankulova, TN | 1 |
Janik, P; Kowalczyk, D; Miłoszewska, J | 1 |
Cmarik, JL; Colburn, NH; Li, Y; Min, H; Ogram, SA; Reeves, R | 1 |
Hui, SW; Jahreis, GP; Johnson, PG; Zhao, YL | 1 |
Colburn, NH; Dong, Z; Huang, C; Li, JJ; Pennie, WD; Watts, RG; Young, MR | 1 |
Snawder, JE | 1 |
Chow, DA; Wang, H | 1 |
Dhalluin, S; Elias, Z; Gate, L; Nguyen-Ba, G; Pages, N; Poirot, O; Tapiero, H; Vasseur, P | 1 |
Fusco, A; Li, Z; Portella, G; Santoro, M; Sferratore, F; Vecchio, G; Vitagliano, D | 1 |
Arturi, F; Chiefari, E; Filetti, S; Fusco, A; Iuliano, R; Russo, D; Stella, A; Trapasso, F | 1 |
Bahram, F; Larsson, LG; Lüscher, B; Oberg, F; Wu, S | 1 |
Matsunaga, S; Tanaka, R | 1 |
Chen, XN; Elisei, R; Fagin, JA; Gonsky, R; Knauf, JA; Korenberg, JR; Liron, T; Mochly-Rosen, D | 1 |
Colburn, N; Flavell, RA; Hunziker, R; Li, JJ; Rincón, M; Sathyanarayana, BK; Young, MR | 1 |
Jiang, J; Wu, Y; Yu, B; Yu, Z | 1 |
Gurley, KE; Kemp, CJ; Philipp, J; Seidel, K; Vo, K | 1 |
Owens, DM; Smart, RC; Wei, S | 1 |
Dong, Z; Huang, C; Li, J; Ma, WY | 1 |
Foster, DA; Frankel, P; Hornia, A; Joseph, T; Lu, Z; Sukezane, T; Zhong, M | 1 |
Colburn, NH; Jansen, AP; Verma, AK | 1 |
Greenhalgh, DA; Liefer, KM; Roop, DR; Wang, XJ | 1 |
Cmarik, JL; Colburn, NH; Hegamyer, G; Kulesz-Martin, M; Matsuhashi, S; Min, H; Yoshinaga, H; Zhan, S | 1 |
Hiranuma, H; Jikko, A; Maeda, T | 1 |
Dartsch, D; Marotzki, S; Marquardt, H; Schäfer, W; Wölfle, D | 1 |
Gau, E; Geisen, C; Haas, K; Karsunky, H; Möröy, T; Schmidt, T; Zevnik, B | 1 |
Chou, C; Lin, Y; Mettling, C | 1 |
Ali, AM; Koshimizu, K; Mat-Salleh, K; Murakami, A; Ohigashi, H | 1 |
Heckman, CA; Mukherjee, R; Plummer, HK | 1 |
Guan, KL; Stewart, S | 1 |
Blalock, WL; Bosch, E; Cherwinski, H; Franklin, RA; Hoyle, PE; McCubrey, JA; McMahon, M; Moye, PW; Pearce, M; Steelman, LS | 1 |
Acs, P; Beheshti, M; Blumberg, PM; Li, L; Szállási, Z; Yuspa, SH | 1 |
Chambers, AF; Chang, PL | 1 |
Nakamura, Y; Noda, Y; Noro, K; Noro, T; Ohki, T; Tomita, I; Warashina, T | 1 |
Blank, M; Goodman, R; Jin, M | 1 |
Cmarik, J; Colburn, NH; Hsu, TC; Young, MR | 1 |
Conigrave, AD; Morris, MB; van der Weyden, L | 1 |
Brinkley, BR; Go, C; He, W; Huang, J; Li, P; Wang, XJ; Zhong, L | 1 |
Beltrán, L; Bol, D; Carbajal, S; Chan, K; DiGiovanni, J; Jorcano, J; Kiguchi, K; Moats, S | 1 |
Bode, AM; Chen, N; Dong, Z; Ma, W; Nomura, M | 1 |
Bureau, JP; Carillo, S; Guiraud, I; Henry, L; Lavabre-Bertrand, T | 1 |
Kato-Masatsuji, E; Tsuchiya, T; Tsuzuki, T; Umeda, M | 1 |
Dolnikov, A; Millington, M; Sun, LQ; Symonds, G | 1 |
Colburn, NH | 1 |
Klein-Szanto, A; Zhang, S | 1 |
Cmarik, JL; Colburn, NH; Jansen, AP; Nair, R; Shibahara, K; Verma, AK; Yang, HS | 1 |
Abbas, T; Barile, N; Chatakondu, K; Foster, DA; Hornia, A; Kaplan, P; Lu, Z; Zhong, M | 1 |
Bode, AM; Chen, N; Dong, Z; Flavell, RA; Ma, WY; Nomura, M; She, QB; Wang, L | 1 |
Camalier, CE; Colburn, NH; Hegamyer, GA; Hsu, TC; Nair, R; Tulsian, P; Young, MR | 1 |
Peng, Z; Wei, Y; Zhao, X | 1 |
Cho, MH; Fang, MZ; Kim, DY; Lee, HW | 1 |
Bibus, DM; Bode, AM; Dong, Z; Holman, RT; Liu, G; Ma, WY | 1 |
Dong, Z; Kaji, A; Ma, W; Miyamoto, K; Nomura, M | 1 |
Owens, DM; Watt, FM | 1 |
Kriehuber, R; Richard, D; Simkó, M; Weiss, DG | 1 |
DiPaolo, JA; Doniger, J; Evans, CH; Popescu, NC | 2 |
Bode, A; Dong, Z; Ho, CT; Liu, G; Ma, WY; Sang, S | 1 |
Sakai, A | 1 |
Bode, AM; Chen, N; Dong, Z; Liu, G; Ma, WY; She, QB; Wu, E | 1 |
Fujiki, H; Iida, N; Kishimoto, T; Kurusu, M; Ohshima, S; Okabe, S; Saeki, Y; Suganuma, M | 1 |
Conti, CJ; Gómez-Casero, E; Jorcano, JL; Larcher, F; Navarro, M; Paramio, JM; Rodríguez-Puebla, ML | 1 |
Czaja, MJ; Dannenberg, AJ; de Lédinghen, V; Liu, H; Lo, CR; Subbaramaiah, K; Zhang, F | 1 |
Brown, N; Bucheimer, N; Chapp, C; Colburn, NH; Hsu, TC; Nair, R; Tulsian, P; Young, MR | 1 |
Davie, JR; Strelkov, IS | 1 |
Clark, SS; Elegbede, JA; Jenkins, GJ; Perman, SM; Sahin, MB | 1 |
Bias, NE; Helson, L; Kopelovich, L | 1 |
Christman, JK; Copp, RP; Pedrinan, L; Whalen, CE | 1 |
Chouroulinkov, I; Lasne, C | 1 |
Fisher, PB; Goldstein, NI; Weinstein, IB | 1 |
Stenbäck, F | 1 |
Blumberg, PM; Driedger, PE | 1 |
Goldfarb, RH; Quigley, JP | 1 |
Easton, TG; Maelicke, A; Miskin, R; Reich, E | 1 |
Easton, TG; Miskin, R; Reich, E | 1 |
Bissell, MJ; Calvin, M; Hatié, C | 1 |
Reich, E; Wilson, EL | 1 |
Blumberg, PM; Delclos, KB | 1 |
Edwards, CA; Martin, RG; Setlow, VP; Vembu, D | 1 |
Basilico, C; Zouzias, D | 1 |
Comoglio, PM; Monti-Bragadin, C; Pani, B; Prat, M; Tarone, G | 1 |
Eisenberg, D; Fisher, PB; Ginsberg, HS; Weinstein, IB | 1 |
Kinsella, AR; Radman, M | 1 |
Marx, JL | 1 |
Bozzone, JH; Fisher, PB; Weinstein, IB | 1 |
Fisher, PB; Lee, LS; Mufson, A; Weinstein, IB; Yamasaki, H | 1 |
Goerttler, K; Komitowski, D; Löhrke, H | 1 |
Kennedy, AR; Little, JB; Nagasawa, H | 1 |
Colburn, NH; Former, BF; Nelson, KA; Yuspa, SH | 1 |
Diamond, L; O'Brien, TG | 3 |
Brankow, DW; Heidelberger, C; Mondal, S; Peterson, AR; Thon, W | 1 |
Holtzer, H; Pacifici, M | 1 |
Heidelberger, C; Kennedy, AR; Little, JB; Mondal, S | 1 |
Bates, JR; Bruegge, WF; Colburn, NH; Gray, RH; Kelsey, WH; Rossen, JD; Shimada, T | 1 |
Getz, MJ; Moses, HL; Proper, JA; Volkenant, ME; Wells, DJ | 1 |
Brankow, DW; Heidelberger, C; Mondal, S | 2 |
Heidelberger, C; Mondal, S | 1 |
Pienta, RJ; Poiley, JA; Raineri, R | 1 |
Blumberg, PM; Driedger, PE; Rossow, PW | 1 |
Weinstein, IB; Wigler, M | 1 |
Hilberg, F; Wagner, EF | 1 |
Endo, Y; Kida, Y; Mai, M; Sasaki, T; Sato, H; Seiki, M; Tanaka, J | 1 |
Inoue, T; Ishida, Y; Kaku, K; Kaneko, T; Sasaki, H; Yoshida, T | 1 |
Caamano, J; Garcia-Palazzo, I; Harris, CC; Iizasa, T; Klein-Szanto, AJ; Metcalf, R; Momiki, S; Welsh, J | 1 |
Cabot, MC; Huang, C | 1 |
Daub, R; Garcia, JG; Harrington, MA; Song, A; Stasek, J | 1 |
Hu, P; Li, W; Schlessinger, J; Skolnik, EY; Ullrich, A | 1 |
Enomoto, T; Sawada, S; Tauchi, H | 1 |
Glick, A; Greenhalgh, D; Hennings, H; Morgan, D; Welty, D; Yuspa, SH | 1 |
Dlugosz, AA; Mischak, H; Mushinski, JF; Yuspa, SH | 1 |
Dougherty, N; Larue, L; Mintz, B; Porter, S | 1 |
Holmsen, H; Lillehaug, JR; Skar, R; Vassbotn, FS | 1 |
Rivedal, E; Roseng, LE; Sanner, T | 1 |
Jooss, K; Müller, R | 1 |
Baxter, CS; Leikauf, GD; Smith, JS; Wey, HE | 1 |
Zwijsen, RM | 1 |
Kumar, S; Rani, AS | 1 |
Hosick, HL; Kanazawa, T | 1 |
Auwerx, J; Sassone-Corsi, P | 1 |
Lin, JK; Wu, FY; Wu, WS | 1 |
Aguelon, AM; Nakazawa, H; Yamasaki, H | 1 |
Albino, AP; Houghton, AN; Jhanwar, SC; Nanus, DM; Sozzi, G | 1 |
Hawkes, SP; Yang, TT | 1 |
Bernstein, LR; Bravo, R; Colburn, NH | 1 |
Mesnil, M; Nakazawa, H; Yamasaki, H | 1 |
Borowski, P; Buck, F; Fanick, W; Harbers, M; Hilz, H; Hinsch, KD; Lengyel, H | 1 |
Kato, R; Wang, JC; Yamamoto, S | 1 |
Ben-Ari, ET; Bernstein, LR; Colburn, NH | 1 |
Boswell, HS; Burgess, GS; Litz-Jackson, S; Miller, AH | 1 |
Colburn, NH; Hirano, K; Smith, BM | 1 |
Benusiglio, E; Granger-Schnarr, M; Sassone-Corsi, P; Schnarr, M | 1 |
DiGregorio, FM; Hashimoto, K; Ishihara, M; Pietruk, T; Richards, J; Setoyama, M; Zarbo, RJ | 1 |
Birnie, GD; Mitchell, LS; Neill, RA | 1 |
Chang, C; Kumar, CC | 1 |
Chieco-Bianchi, L; Forino, M; Majone, F; Saggioro, D; Turchetto, L | 1 |
Bartoli, S; Colacci, A; Da Via, C; Grilli, S; Perocco, P; Silingardi, P; Vaccari, M | 1 |
Coder, DM; Garrett, LR; McDougall, JK | 1 |
Brissette, JL; Dotto, GP; Gilula, NB; Kumar, NM | 1 |
Bonham, K; Bowden, GT; Krieg, P; Ostrowski, LE | 1 |
Cheng, SJ; Li, MX; Lu, FX | 1 |
Hsu, PL; Hsu, SM | 1 |
Austin, SJ; Beeman, DK; Lasley, JA; Mass, MJ; Schorschinsky, NS | 2 |
Afar, DE; Bell, JC; Braun, PE; Roder, J; Salzer, JL | 1 |
Datta, R; Kharbanda, S; Kufe, D; Nakamura, T; Sherman, ML | 1 |
Berkovic, D; Doenecke, D; Eibl, H; Hochhuth, C; Unger, C | 1 |
Dorkin, HL; Grubman, SA; Iannuzzi, MC; Jefferson, DM; Klinger, KW; Li, M; Marini, FC; Valentich, JD; Welsh, MJ | 1 |
Alitalo, K; Comoglio, PM; Di Renzo, MF; Koskinen, P; Lehtola, L; Lehväslaiho, H; Sistonen, L | 1 |
Fürstenberger, G; Krieg, P; Marks, F; Schnapke, R; Vogt, I | 1 |
Meadows, GG; Thrall, BD | 1 |
Faller, DV; Mundschau, LJ; Quiñones, MA; Rake, JB | 1 |
Hara, J; Inoue, M; Ishihara, S; Koizumi, S; Kurahashi, H; Murayama, N; Okamura, J; Tawa, A; Toyoda, Y; Yumura-Yagi, K | 1 |
el-Okda, MO; Hsu, PL; Hsu, SM; Xie, SS | 1 |
Carney, DH; Fenton, JW; Morris, DL; Nechay, P; Ward, JB; Whorton, EB | 1 |
Gélinas, C; Kumar, S; McDonnell, PC; Rabson, AB | 1 |
Colburn, NH; De Benedetti, F; Falk, L; Faltynek, CR; Oppenheim, JJ; Ruscetti, FW | 1 |
Bauer, G; Götschl, M; Höfler, P | 1 |
Embleton, MJ; Noy, RJ | 1 |
Das, UN | 1 |
Rieber, M; Rieber, MS | 1 |
Godwin, AK; Lieberman, MW | 1 |
Borner, C; Filipuzzi, I; Imber, R; Weinstein, IB | 1 |
Cuddy, MP; Rapp, UR; Reed, JC; Turner, BC; Yum, S | 1 |
Biozzi, G | 1 |
Carbone, A; Gusella, GL; Radzioch, D; Varesio, L | 1 |
Goppelt-Struebe, M; Hass, R; Rehfeldt, W | 1 |
Greenhalgh, DG; Hennings, H; Robinson, VA; Welty, DJ; Yuspa, SH | 1 |
Crawford, DR; Greenberger, JS | 1 |
Balmain, A; Burns, PA; Haddow, S; Jack, A; Neilson, F | 1 |
Mikalsen, SO; Rivedal, E; Sanner, T | 2 |
Chiu, R; Karin, M; Yang-Yen, HF | 1 |
Alitalo, K; Bravo, R; Koskinen, PJ; Lehtola, L; Lehväslaiho, H; Sistonen, L | 1 |
Greene, MI; Qian, XL; Wada, T | 1 |
Ishidate, M; Mizusawa, H; Sakai, A; Sasaki, K | 1 |
Fabbro, D; Imber, R | 1 |
Mason, SN; Weinberg, JB | 1 |
Borek, C; Merrill, AH; Ong, A; Stevens, VL; Wang, E | 1 |
Kennedy, AR; Su, LN; Toscano, WA | 1 |
Balcer-Kubiczek, EK; Harrison, GH | 5 |
Anderson, WB; Kiss, Z; Pettit, GR; Rapp, UR | 1 |
Furukawa, M; Hamada, T; Ishii, M; Kono, T; Mizuno, N; Taniguchi, S; Tanii, T; Yoshizato, K | 1 |
Kuroki, T; Nose, K; Saito, H | 1 |
Katoh, S; Matsuda, I; Matsumoto, R; Migita, M; Mita, S; Sonoda, E; Takatsu, K; Tominaga, A; Tsuchiya, H; Yamaguchi, N | 1 |
Hirayama, C; Hirayoshi, K; Nagata, K; Nakai, A; Ohtsuka, K | 1 |
Nori, M; Shawver, LK; Weber, MJ | 1 |
Belman, S; Bosland, MC; Estensen, RD; Savarese, K; Sellakumar, A | 1 |
Fialkow, PJ; Reddy, AL | 1 |
Han, KK; Wu, J; Zhu, DX; Zhu, JQ | 1 |
Datta, R; Imamura, K; Kufe, DW; Sherman, ML; Stone, RM | 1 |
Lin, MC; Wu, YY | 1 |
Bernard, HU; Chan, WK; Chong, T; Klock, G | 1 |
Collier, IE; Frisch, SM; Genrich, LT; Goldberg, GI; Martin, G; Reich, R | 1 |
Han, JW; Macara, IG; Sadowski, H; Young, DA | 1 |
Alitalo, K; Alitalo, R; Andersson, L; Hölttä, E; Partanen, J; Pertovaara, L; Sistonen, L | 1 |
Brennan, A; Estridge, JK; Katz, DR; Kemp, LM; Latchman, DS | 1 |
Flaegstad, T; Moens, U; Sundsfjord, A; Traavik, T | 1 |
Hsu, PL; Hsu, SM; Xie, SS | 1 |
Etscheid, BG; Jamieson, GA; Toscas, K; Villereal, ML | 1 |
Nebert, DW; Owens, RA | 1 |
Garcin, D; Jacquemont, B; Madjar, JJ; Massé, T | 1 |
Chambers, AF; Craig, AM; Denhardt, DT; Edwards, DR; Guo, XJ; Murphy, LC; Parfett, CL; Reid, RE; Waterhouse, P | 1 |
Burstein, DE; Lacal, JC; Pellicer, A; Thomson, TM; Trotta, RJ | 1 |
Ishidate, M; Mizusawa, H; Sasaki, K; Tanaka, N | 1 |
Boswell, HS; Burgess, GS; Gabig, TG; Harrington, MA; Inhorn, L; Nahreini, TS; Srivastava, A; Srour, EF | 1 |
Burns, FJ | 1 |
Facy, P; Hubert, J; Hubert, M; Monsigny, M; Seve, AP | 1 |
Arcuri, RA; De Souza, MH; Marques-Silva, VM; Rumjanek, VM; Teixeira, MC | 1 |
Kolman, A; Näslund, M; Osterman-Golkar, S | 1 |
Cardiff, RD; Kuo, A; Leder, A; Leder, P; Sinn, E | 1 |
Earp, HS; Grisham, JW; Raymond, VW | 1 |
Birnie, GD; Jamieson, T; Neill, R; Vass, JK | 1 |
Château, MT; Marti, J; Pacaud, M; Taimi, M | 1 |
Aronow, BJ; Fugman, DA; Jones, CL; Lieberman, MA; Witte, DP | 1 |
Inui, N; Semba, M | 2 |
Archer, LT; Bales, WD; Bass, RA; Bell, PB; Hemstreet, GP; Hurst, RE; Jones, PL; Rao, JY | 1 |
Chouroulinkov, I; Lasne, C; Lu, YP; Orfila, L; Ventura, L | 1 |
Heine, UI; Kenney, S; Rice, JM; Riggs, CW; Yamadori, I | 1 |
Chandra, A; Chandra, P; Gerber, T; Massa, T; Pfaffenholz, V; Schlatterer, B | 1 |
Bortner, DM; Ostrowski, MC; Owen, RD | 1 |
Billings, PC; Habres, JM; Kennedy, AR | 1 |
Baron, PL; Carchman, RA; Collins, JM; Koretz, MJ; Parker, GA; Tokarz, AS | 1 |
Crowcroft, NS; Parkinson, EK; Quigley, JP; Stanley, MA | 1 |
Parkinson, EK | 2 |
Albino, AP; Eisinger, M; Houghton, AN; Kantor, RR; Lee, JS; Old, LJ; Oliff, AI | 1 |
Jani, H; Knowles, MA | 1 |
Olson, SA; Shawver, LK; Weber, MJ; White, MK | 1 |
Kuratomi, Y; Kuwano, M; Masumi, S; Ono, M; Yasutake, C | 1 |
Alcorta, DA; Blenis, J; Erikson, RL; Kuo, CJ | 1 |
Cheng, CK; Krieg, TM; Mehrel, T; Roop, DR; Yuspa, SH | 1 |
Aldaz, CM; Conti, CJ | 1 |
Conklin, BR; Felder, CC; Ma, AL | 1 |
Buchou, T; Charollais, RH; Fagot, D; Mester, J | 1 |
Choi, JK; Shalloway, D; Yaciuk, P | 1 |
Cole, MD; Mango, SE; Schuler, GD; Steele, ME | 1 |
Aller, P; Rius, C | 1 |
Miller, DR; Morris, RJ; O'Connell, JF; Patskan, GP; Slaga, TJ; Tacker, K; Viaje, AV | 1 |
Athar, M; Bickers, DR; Lloyd, JR; Mukhtar, H | 1 |
Fujita, H; Kuzumaki, N; Oda, A; Ogiso, Y; Suzuki, H; Uchino, J | 1 |
Imler, JL; Wasylyk, B | 1 |
Cheng, SJ | 1 |
Bernstein, LR; Colburn, NH | 1 |
Ibaraki, T; Ito, Y; Satake, M; Yamaguchi, Y | 1 |
Bonfil, RD; Fridman, R; Harris, CC; Klein-Szanto, A; Momiki, S; Reddel, R; Reich, R | 1 |
Bonham, K; Bowden, GT; Cress, AE; Embry, T; Gibson, D; Jaffe, DR; Roberts, RA | 1 |
Steele, VE | 1 |
Dull, TJ; Honegger, AM; Riedel, H; Schlessinger, J; Ullrich, A | 1 |
Bowden, GT; Jaffe, DR | 1 |
Jain, AK; Nakamura, Y; Sano, M; Shimoi, K; Tomita, I | 1 |
Chan, TC | 1 |
Borowski, P; Harbers, M; Hilz, H; Kischel, T; Müller, K; Stabel, S | 1 |
Gilmour, SK; O'Brien, TG | 1 |
Hsiao, WL; Lopez, CA; Weinstein, IB | 1 |
Cooper, CS; Darling, J; Lantos, PL; Pilkington, GJ; Reeves, BR; Stratton, MR | 1 |
Dotto, GP; el-Fouly, MH; Nelson, C; Trosko, JE | 1 |
Birnbaum, MJ; Garcia de Herreros, A; Hiraki, Y | 1 |
Fujiki, H; Ikeda, I; Kitani, H; Nagao, M; Rapp, U; Sakai, R; Sugimura, T; Takaku, F | 1 |
Fiebig, H; Grunicke, H; Hofmann, J; Maly, K; Oberhuber, H; Posch, L; Uberall, F | 1 |
Barrett, JC; Gray, T; Nelson, K; Nettesheim, P; Tanaka, N | 1 |
Craig, AM; Denhardt, DT; Smith, JH | 1 |
Alitalo, K; Bos, TJ; Keski-Oja, J; Pertovaara, L; Sistonen, L; Vogt, PK | 1 |
Dugina, VB | 1 |
Elkind, MM; Han, A; Hill, CK | 2 |
Barni, S; Meloni, MA; Pippia, P; Sciola, L; Tilloca, G | 1 |
Collins, RD; Cousar, JB; Kinney, MC; Vogler, LB; Whitlock, J | 1 |
Earp, HS; Grisham, JW; Lee, DC; Raymond, VW | 1 |
Inoue, R; Kitani, T; Kuratsune, H; Machii, T; Nakamura, Y; Nishimori, Y; Tokumine, Y; Ueda, E; Waki, K | 1 |
Arita, I; Mitani, H; Sasaki, MS; Tachibana, A; Takebe, H; Tatsumi, K; Toyoda, M | 1 |
Sakai, A; Sato, M | 1 |
Colburn, NH; Kligman, D; Patel, J; Simek, SL | 1 |
Antony, M; Mehrotra, NK; Shukla, Y | 1 |
Colburn, NH; Gindhart, TD; Nakamura, Y; Seed, JL; Tomita, I; Winterstein, D | 1 |
Bailly, J; Bernard, BA; Darmon, M; Delescluse, C; Fürstenberger, G; Marks, F; Sorg, B | 1 |
Obom, KM; Pogo, BG | 1 |
Barber, JR; Sassone-Corsi, P; Verma, IM | 2 |
Cabot, MC; Cao, HT; Chabbott, H; Lebowitz, M; Welsh, CJ; Zhang, ZC | 1 |
Daniel, LW; Krebs, CR; Kucera, LS; Roddick, VL; Waite, M | 1 |
Ashmun, RA; Downing, JR; Rettenmier, CW; Roussel, MF; Sherr, CJ | 1 |
Bentley, KS; Fatteh, MV; Grisham, JW; Lee, LW; Smith, GJ | 1 |
Morgan, EH; Sorokin, LM; Yeoh, GC | 1 |
Chouroulinkov, I; Lasne, C; Lowy, R; Lu, YP | 1 |
Cohen, B; Druker, B; Kaplan, D; Keller, T; Mamon, H; Morgan, W; Piwnica-Worms, H; Roberts, TM; Schaffhausen, B; Whitman, M | 1 |
Dooley, TP; Hart, IR; Jones, NC; Wilson, RE | 1 |
Kaufman, DG; Nelson, KG; Siegfried, JM | 1 |
Lichti, U; Yuspa, SH | 1 |
Aujard, C; Lafarge-Frayssinet, C; Morel-Chany, E | 1 |
Delhanty, JD; Rider, SH | 1 |
Abernethy, DJ; Boreiko, CJ; Rickert, DE; Stedman, DB | 1 |
Aumailley, M; Chu, ML; Hatamochi, A; Krieg, T; Mauch, C; Timpl, R | 1 |
Carter, T; Chan, E; Greene, B; James, C | 1 |
Blaney, C; Finn, T; Lawlor, E; McCann, SR; Temperley, IJ; Whelan, A | 1 |
Fujinaga, K; Kato, H; Yamashita, T | 1 |
Colburn, NH; Gindhart, TD; Nakamura, Y | 1 |
Pelling, JC; Slaga, TJ | 1 |
Colburn, NH; Gindhart, TD; Hegamyer, GA; Lerman, MI | 1 |
Kensler, TW; Kozumbo, WJ; Trush, MA | 1 |
Gentry, LE; Purchio, AF; Shoyab, M | 1 |
Issinger, OG; Rance, AJ; Thönnes, M | 1 |
Fairbairn, S; Gilbert, R; Ojakian, G; Quigley, JP; Schwimmer, R | 1 |
Abe, E; Chida, K; Hashiba, H; Hosoi, J; Hosomi, J; Kuroki, T; Sasaki, K; Suda, T | 1 |
Chen, KY; Liu, AY | 1 |
Altman, A; Isakov, N | 1 |
Abe, E; Chida, K; Hashiba, H; Kamata, N; Kuroki, T; Sasaki, K; Suda, T | 1 |
Kanno, Y | 1 |
Garte, SJ | 1 |
Colburn, NH; Hegamyer, GA; Lerman, MI | 1 |
Angel, P; Herrlich, P; Lücke-Huhle, C; Pöting, A; Rahmsdorf, HJ | 1 |
Kraft, AS | 1 |
Buzhiyevskaya, TI; Lukash, LL; Shapiro, NI; Varshaver, NB | 1 |
Müller, R | 1 |
Bertram, JS; Martner, JE | 2 |
Kakunaga, T; Sagara, J; Yamada, KM | 1 |
Abe, E; Colburn, NH; Hosoi, J; Kuroki, T; Suda, T | 1 |
Bishop, JM; Klempnauer, KH; Moscovici, C; Moscovici, G; Snyder, M; Symonds, G | 1 |
Ono, T; Tanaka, K; Umeda, M | 2 |
Barrett, JC; Gilmer, TM; Jetten, AM | 1 |
Hiwasa, T; Sakiyama, S; Tanigawara, C | 1 |
Colburn, NH; Lerman, MI; Sakai, A; Yao, KT | 1 |
Clark, EJ; Frisch, SM; Werb, Z | 1 |
Inui, N; Ohkawa, Y; Saito, M; Tanaka, N | 1 |
Kennedy, AR; Symons, MC | 1 |
Poulin, L; Skalski, V; Wainberg, MA | 1 |
Gorbunova, LV; Raevskaia, GB; Shapiro, NI; Varshaver, NB | 1 |
Ashendel, CL; Taparowsky, EJ; Weyman, CM; Wolfson, M | 1 |
Callaham, MF; Huberman, E; Jones, CA | 1 |
Kakunaga, T; Kawamoto, T; Makino, K; Niwa, H; Orita, S; Sugiyama, H | 1 |
Huang, M; Kamata, N; Kuroki, T; Nose, K | 1 |
Colburn, NH; Gindhart, TD; Smith, BM | 2 |
Blumenson, L; Kulesz-Martin, M; Lisafeld, B | 1 |
Mehta, RG; Moon, RC | 1 |
Ernst, SM; Hixson, DC; Nairn, RS; Patskan, G; Pelling, JC; Rhode, SL; Slaga, TJ | 1 |
Hsiao, WL; Weinstein, IB; Wu, T | 1 |
Lockney, MW; Marvel, CC; Moskal, JR; Sweeley, CC; Trosko, JE | 1 |
Danner, MW; Marian, B | 1 |
Flier, JS; Lodish, HF; Mueckler, MM; Usher, P | 1 |
Benjamin, CW; Gorman, RR; Tarpley, WG | 1 |
Brown, CC; Chu, KC; Tan, WY; Tarone, RE | 1 |
Garland, JM | 1 |
Kitagawa, S; Miura, Y; Ohta, M; Saito, M; Takaku, F | 1 |
Colburn, NH; Nakamura, Y; Smith, BM; Wendel, EJ; Winterstein, D | 1 |
Ishidate, M; Mizusawa, H; Sasaki, K | 1 |
Bryan, GT; Reznikoff, CA; Verma, AK | 1 |
Colburn, NH; Gindhart, TD; Hegameyer, GA; Nakamura, Y; Smith, BM; Stevens, LA; West, MW | 1 |
Alitalo, K; Alitalo, R; Andersson, LC; Koskinen, P; Mäkelä, TP | 1 |
Horiuchi, T; Kusaba, T; Mayumi, T; Nagasawa, K | 1 |
Colburn, NH; Dion, LD; Gindhart, TD | 1 |
Horikoshi, J; Kaneko, M | 1 |
Baturay, NZ; Trombetta, LD | 1 |
Lichtman, MA; Segel, GB; Woodlock, TJ | 1 |
Gschwendt, M; Kittstein, W; Marks, F | 1 |
Colburn, NH; Dowjat, WK; Shimada, T; Smith, BM; Wendel, EJ | 1 |
Firestein, GS; Gruber, HE; Reifler, D; Richman, D | 1 |
Kennedy, AR; Umans, RS | 1 |
Mordan, LJ | 1 |
Hirokawa, M; Kudo, K; Miura, AB; Takahashi, T; Takatsu, H; Yoshida, K | 1 |
Bowden, GT; Gensler, HL; Moriguchi, S; Watson, RR | 1 |
Dugina, VB; Gelfand, IM; Svitkina, TM; Vasiliev, JM | 1 |
Bhoopalam, N; Drexler, HG; Gaedicke, G; Klein, M; Minowada, J | 1 |
Campisi, J; Dean, M; Levine, RA; Ran, W | 1 |
Baserga, R; Calabretta, B; Heintz, N; Kaczmarek, L; Kao, HT; Nevins, J | 1 |
Almendral, JM; Bravo, R; Húbsch, D; Macdonald-Bravo, H; Müller, R | 1 |
Colburn, NH; Dowjat, WK; Gindhart, TD; Lerman, MI; Shimada, T | 1 |
Brown, MA; Falco, J; Ihle, JN; Paul, WE; Pierce, JH; Watson, CJ | 1 |
Castagnola, J; MacLeod, C; Mendelsohn, J; Sunada, H; Taetle, R | 1 |
Kodama, M | 1 |
Brankow, DW; Herschman, HR | 2 |
Colburn, NH; Smith, BM | 1 |
Djurhuus, R; Laerum, OD; Lillehaug, JR | 1 |
Bian, SG; Wang, ZC; Yan, WW | 1 |
Bjerkvig, R; Lillehaug, JR; Male, R | 1 |
Baldwin, JK; Fischer, SM; Jasheway, DW; Patrick, KE | 1 |
Brodskaia, RM | 1 |
Chouroulinkov, I; Lasne, C; Lu, YP | 1 |
Kokunai, T; Korosue, K; Matsumoto, S; Tamaki, N | 1 |
Kuroki, T | 1 |
Cerutti, PA; Kozumbo, WJ | 1 |
Abernethy, DJ; Boreiko, CJ; Sanchez, JH | 1 |
Angel, P; Herrlich, P; Mallick, U; Pöting, A; Rahmsdorf, HJ; Schorpp, M | 1 |
Haarr, L; Kleppe, K; Lillehaug, JR | 1 |
Inui, N; Ohkawa, Y; Saito, M | 1 |
Henschler, D; Hildebrandt, AG; Kahl, R; Potenberg, J; Schiffmann, D | 1 |
Best, JB; Hall, F; Morita, M | 2 |
Abernethy, DJ; Boreiko, CJ; Stedman, DB | 1 |
Chouroulinkov, I; Sala, M; Tran, PL | 1 |
Carter, TH; Zelinsky-Papez, K; Zimmerman, JA | 1 |
Chouroulinkov, I; Lasne, C; Lu, YP; Sala, M | 1 |
Aguelon-Pegouries, AM; Enomoto, T; Furstenberger, G; Marks, F; Martel, N; Yamasaki, H | 1 |
Elkind, MM; Hill, CK | 1 |
Brankow, D; Herschman, HR | 1 |
Mitchell, RL; Schreiber, RD; Verma, IM; Zokas, L | 1 |
Arthur, DC; Kersey, JH; Korsmeyer, SJ; Parkin, JL; Stong, RC | 1 |
Gschwendt, M; Horn, F; Kittstein, W; Marks, F | 1 |
Hennings, H; Yuspa, SH | 1 |
Fürstenberger, G; Kinzel, V; Marks, F; Schwarz, M | 1 |
Huberman, E; Jones, CA | 1 |
Bravo, R; Curran, T; Müller, R | 1 |
Aarsaether, N; Berge, RK; Lillehaug, JR; Male, R | 1 |
Borek, C; Cleaver, JE | 1 |
Yamasaki, H | 1 |
Enomoto, T; Kakunaga, T; Kanno, Y; Shiba, Y; Yamasaki, H | 1 |
Wolf, G; Zerlauth, G | 1 |
Johnson, J; Munker, R; Petersmann, I; Riethmüller, G; Schmoeckel, C; Ziegler-Heitbrock, HW | 1 |
Revoltella, RP; Sambuy, Y; Spagnoli, LG; Vigneti, E | 1 |
Clark, EP; Stossel, TP; Weitberg, AB; Weitzman, SA | 1 |
Buzhievskaia, TI; Bykorez, AI; Kononenko, LI; Lukash, LL; Shapiro, NI | 1 |
Barrett, JC; Gray, TE; Nettesheim, P | 1 |
Beeman, DK; Leavitt, SA; Mass, MJ; Siegfried, JM | 1 |
Boreiko, CJ | 2 |
Barrett, JC | 1 |
Abernethy, DJ; Boreiko, CJ; Greenlee, WF; Huband, JC | 1 |
Enomoto, T; Rivedal, E; Sanner, T; Yamasaki, H | 1 |
Gibson, NW; Hartley, JA; Yuspa, SH; Zwelling, LA | 1 |
Higgins, PJ | 1 |
Buzhievskaia, TI; Lukash, LL; Shapiro, NI; Varshaver, NB | 1 |
Barrett, JC; Gray, T; Nettesheim, P | 1 |
Barrett, JC; Nettesheim, P | 1 |
Abernethy, DJ; Boreiko, CJ; Huband, JC | 1 |
De Luca, LM | 1 |
Bruce, SA; Horng, CB; Ts'o, PO | 1 |
43 review(s) available for tetradecanoylphorbol acetate and Cell Transformation, Neoplastic
Article | Year |
---|---|
Molecular mechanisms of tumor promotion and multistage carcinogenesis.
Topics: Adenosine Triphosphate; Animals; Base Sequence; Caenorhabditis elegans Proteins; Carrier Proteins; Cell Transformation, Neoplastic; ErbB Receptors; Humans; Lyngbya Toxins; Molecular Conformation; Neoplasms; Oncogenes; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Kinase C; Protein Kinases; Receptors, Cell Surface; Receptors, Drug; Receptors, Immunologic; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1983 |
Interactions between initiating chemical carcinogens, tumor promoters, and adenovirus in cell transformation.
Topics: Adenoviridae; Animals; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Clone Cells; DNA; Embryo, Mammalian; Female; Pregnancy; Rats; Tetradecanoylphorbol Acetate | 1980 |
Cell culture systems for studying multifactor interactions in carcinogenesis.
Topics: Animals; Carcinogens; Cell Differentiation; Cell Membrane; Cell Transformation, Neoplastic; Cells, Cultured; Cocarcinogenesis; DNA; Drug Evaluation, Preclinical; ErbB Receptors; Humans; Models, Biological; Oncogenic Viruses; Phospholipids; Receptors, Cell Surface; Tetradecanoylphorbol Acetate | 1980 |
Epidermal growth factor receptors interact with transforming growth factors produced by certain human tumor cells and are distinct from specific membrane receptors for phorbol and ingenol esters.
Topics: Animals; Caenorhabditis elegans Proteins; Carcinogens; Carrier Proteins; Cell Adhesion; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cocarcinogenesis; ErbB Receptors; Humans; Neoplasms; Peptides; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Transforming Growth Factors | 1982 |
Prostaglandins and cancer: a review of tumor initiation through tumor metastasis.
Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Cell Differentiation; Cell Division; Cell Transformation, Neoplastic; Cyclooxygenase Inhibitors; DNA; Epoprostenol; Female; Hematopoietic Stem Cells; Humans; Kidney; Male; Mutagens; Neoplasm Metastasis; Neoplasms; Oxidation-Reduction; Prostaglandins; Prostaglandins D; Prostaglandins E; Prostaglandins F; Skin; Tetradecanoylphorbol Acetate; Thromboxane A2 | 1981 |
[Effect of tumor promotor on neoplastic cell transformation].
Topics: Animals; Carcinogens; Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; Guinea Pigs; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Macrophages; Mice; Phorbols; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1983 |
Membrane and genetic events in tumor promotion: studies with promoter resistant variants of JB6 cells.
Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Clone Cells; Drug Resistance; Epidermis; Gangliosides; Genes; Mice; Mice, Inbred BALB C; Oxygen; Phenotype; Superoxide Dismutase; Tetradecanoylphorbol Acetate | 1983 |
Critical biochemical and regulatory events in malignant transformation in vitro.
Topics: Animals; Benzamides; Cell Transformation, Neoplastic; Cricetinae; DNA Repair; Humans; In Vitro Techniques; Mice; Mutation; Neoplasms; Poly Adenosine Diphosphate Ribose; Sister Chromatid Exchange; Tetradecanoylphorbol Acetate; Thyroid Hormones | 1983 |
Molecular and cellular basis for tumor promotion in mouse skin.
Topics: Animals; Calcium; Cell Division; Cell Transformation, Neoplastic; Mice; Oncogenes; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1983 |
Cellular and biochemical changes during multistage skin tumor promotion.
Topics: Animals; Antioxidants; Cell Transformation, Neoplastic; Free Radicals; Gene Amplification; Humans; Mice; Ornithine Decarboxylase; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1983 |
Genetic predisposition to cancer in man: in vitro studies.
Topics: Adenoma; Antigens, Neoplasm; Carcinogens; Cell Division; Cell Membrane; Cell Transformation, Neoplastic; Cells, Cultured; Cholesterol; Colonic Neoplasms; Cytoskeleton; Disease Susceptibility; Fibroblasts; Fibronectins; Genes, Dominant; Humans; Mitochondria; Mutation; Neoplasms; Rectal Neoplasms; Tetradecanoylphorbol Acetate | 1982 |
Potent tumor promoters other than phorbol ester and their significance.
Topics: Alkaloids; Animals; Cell Adhesion; Cell Aggregation; Cell Transformation, Neoplastic; Enzyme Induction; Humans; Isomerism; Lactones; Lyngbya Toxins; Marine Toxins; Mice; Mollusk Venoms; Neoplasms; Ornithine Decarboxylase; Phorbols; Tetradecanoylphorbol Acetate | 1982 |
In vitro studies on the mode of action of the phorbol esters, potent tumor promoters: part 1.
Topics: Animals; Blood Cells; Cell Membrane; Cell Transformation, Neoplastic; Cells, Cultured; Chick Embryo; Hormones; Humans; Mice; Microtubules; Mitosis; Nucleotides, Cyclic; Phorbol Esters; Phorbols; Phospholipids; Polyamines; Tetradecanoylphorbol Acetate | 1980 |
In vitro studies on the mode of action of the phorbol esters, potent tumor promoters, part 2.
Topics: Animals; Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; Clone Cells; DNA Repair; Models, Biological; Mutagens; Mutation; Neoplasms, Experimental; Phorbol Esters; Phorbols; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1981 |
Phenotypic and chromosomal alterations in cell cultures as indicators of tumor-promoting activity.
Topics: Animals; Carcinogens; Cell Adhesion; Cell Communication; Cell Differentiation; Cell Division; Cell Membrane; Cell Transformation, Neoplastic; Cells, Cultured; Chromosome Aberrations; Cocarcinogenesis; Fibronectins; Humans; Neoplasms, Experimental; Ornithine Decarboxylase; Plasminogen Activators; Tetradecanoylphorbol Acetate; Tretinoin | 1982 |
Inhibition of cell-cell communication by tumor promoters.
Topics: Animals; Biological Assay; Calcium; Carcinogens; Cell Communication; Cell Differentiation; Cell Division; Cell Line; Cell Membrane; Cell Transformation, Neoplastic; Cocarcinogenesis; Contact Inhibition; Gene Expression Regulation; Intercellular Junctions; Models, Biological; Mutation; Receptors, Drug; Tetradecanoylphorbol Acetate | 1982 |
International Commission for Protection against Environmental Mutagens and Carcinogens ICPEMC working paper 2/8: An evaluation of assay procedures for detection of tumor promotors.
Topics: Animals; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cocarcinogenesis; Mice; Mutagenicity Tests; Rats; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1982 |
Effect of conjugated linoleic acid on carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antimutagenic Agents; Cell Transformation, Neoplastic; Female; Gastrointestinal Neoplasms; Linoleic Acids; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred ICR; Rats; Rats, Inbred F344; Signal Transduction; Tetradecanoylphorbol Acetate | 1994 |
Positive and negative growth regulation in melanoma: growth factors, intracellular signalling, and the cell cycle.
Topics: Animals; Cell Cycle; Cell Transformation, Neoplastic; Fibroblast Growth Factor 2; Growth Substances; Humans; Melanocytes; Melanoma; Protein Kinase C; Protein Kinases; Signal Transduction; Tetradecanoylphorbol Acetate | 1993 |
[Terpenoids and steroids from several euphorbiaceae and pinaceae plants].
Topics: Animals; Cell Transformation, Neoplastic; Euphorbiaceae; HeLa Cells; Humans; Mice; Molecular Conformation; Steroids; Terpenes; Tetradecanoylphorbol Acetate; Topoisomerase I Inhibitors; Trees | 1999 |
Activator protein 1 (AP-1)- and nuclear factor kappaB (NF-kappaB)-dependent transcriptional events in carcinogenesis.
Topics: Animals; Apoptosis Regulatory Proteins; Carcinogens; Cell Transformation, Neoplastic; Clone Cells; Epidermal Cells; Epidermal Growth Factor; Epidermis; Gene Expression Regulation, Neoplastic; Humans; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neoplasm Proteins; NF-kappa B; Oxidation-Reduction; Oxidative Stress; Phenotype; Protein Biosynthesis; Proteins; Reactive Oxygen Species; RNA-Binding Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription, Genetic; Transcriptional Activation; Transfection; Tumor Necrosis Factor-alpha | 2000 |
Signal transduction and white cell maturation via extracellular ATP and the P2Y11 receptor.
Topics: Actins; Adenosine Triphosphate; Blotting, Northern; Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; Flow Cytometry; HL-60 Cells; Humans; Leukocytes; N-Formylmethionine Leucyl-Phenylalanine; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; Receptors, Purinergic P2; RNA, Messenger; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate | 2000 |
[The proteasome and malignant hemopathies].
Topics: Biomarkers, Tumor; Cell Differentiation; Cell Membrane; Cell Nucleus; Cell Transformation, Neoplastic; Cysteine Endopeptidases; Cytoplasm; Enzyme-Linked Immunosorbent Assay; Hematologic Neoplasms; Humans; L-Lactate Dehydrogenase; Leukemia-Lymphoma, Adult T-Cell; Multienzyme Complexes; Neoplasm Proteins; Neoplasms; Proteasome Endopeptidase Complex; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured; U937 Cells; Vitamin D | 2000 |
Synergistic effect of tumor virus transformation and tumor promoter treatment on the production of plasminogen activator by chick embryo fibroblasts.
Topics: Avian Sarcoma Viruses; Cell Transformation, Neoplastic; Cells, Cultured; Models, Biological; Phorbols; Plasminogen Activators; Tetradecanoylphorbol Acetate | 1978 |
Action of phorbol esters in cell culture: mimicry of transformation, altered differentiation, and effects on cell membranes.
Topics: Adenoviruses, Human; Animals; Arachidonic Acids; Cell Differentiation; Cell Membrane; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Female; HeLa Cells; Humans; Kinetics; Membrane Fluidity; Membrane Lipids; Mice; Phorbols; Prostaglandins; Rats; Tetradecanoylphorbol Acetate | 1979 |
Interaction and distinction of genotoxic and non-genotoxic events in carcinogenesis.
Topics: 3T3 Cells; 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Humans; Mice; Mutagens; Neoplasms; Risk Factors; Tetradecanoylphorbol Acetate | 1992 |
Differential gene expression during tumor promotion and progression in the mouse skin model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Actins; Animals; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cocarcinogenesis; DNA; Gene Expression Regulation, Neoplastic; Matrix Metalloproteinase 3; Metalloendopeptidases; Methylnitronitrosoguanidine; Mice; Neoplasm Metastasis; Neoplasm Proteins; Neoplasms, Multiple Primary; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Ubiquitins | 1991 |
Nonmutagenic mechanisms in carcinogenesis: role of protein kinase C in signal transduction and growth control.
Topics: Animals; Bacteria; Cell Line, Transformed; Cell Transformation, Neoplastic; Cocarcinogenesis; Colon; Colonic Neoplasms; Diglycerides; Enzyme Activation; Enzyme Induction; Fibroblasts; Gene Expression Regulation, Neoplastic; Humans; Isoenzymes; Mice; Protein Kinase C; Proto-Oncogenes; Signal Transduction; Tetradecanoylphorbol Acetate | 1991 |
Arachidonic acid as a mediator of some of the actions of phorbolmyristate acetate, a tumor promoter and inducer of differentiation.
Topics: Animals; Arachidonic Acids; Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; Humans; Oncogenes; Tetradecanoylphorbol Acetate | 1991 |
Promotion and progression in carcinogenesis.
Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Disease Models, Animal; Mice; Papilloma; Rats; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1990 |
The conversion stage of skin carcinogenesis.
Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Mice; Models, Biological; Papilloma; Phorbol Esters; Precancerous Conditions; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1990 |
Defective responses of transformed keratinocytes to terminal differentiation stimuli. Their role in epidermal tumour promotion by phorbol esters and by deep skin wounding.
Topics: Animals; Carcinogens; Cell Differentiation; Cell Transformation, Neoplastic; Epidermis; In Vitro Techniques; Keratins; Mice; Mitosis; Oncogenes; Papilloma; Peptides; Phenotype; Phorbols; Protein Kinase C; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transforming Growth Factors | 1985 |
The premalignant nature of mouse skin papillomas: histopathologic, cytogenetic, and biochemical evidence.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biomarkers, Tumor; Cell Transformation, Neoplastic; Chromosome Aberrations; Chromosome Disorders; Karyotyping; Keratins; Mice; Papilloma; Precancerous Conditions; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1989 |
Investigations of multistage carcinogenesis: applications of in vitro-in vivo studies.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Differentiation; Cell Line, Transformed; Cell Transformation, Neoplastic; Cells, Cultured; Methylnitronitrosoguanidine; Mice; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
AP1, a composite transcription factor implicated in abnormal growth control.
Topics: Animals; Cell Division; Cell Transformation, Neoplastic; DNA-Binding Proteins; Humans; Oncogenes; Proto-Oncogene Proteins c-jun; Tetradecanoylphorbol Acetate; Transcription Factors | 1989 |
Cellular mechanisms for tumor promotion and enhancement.
Topics: Animals; Cell Transformation, Neoplastic; Cocarcinogenesis; ErbB Receptors; Humans; Kidney Neoplasms; Liver Neoplasms; Oncogenes; Protein Kinase C; Protein Kinases; Receptors, Cell Surface; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1985 |
Modulation of cell communication and carcinogenesis.
Topics: Animals; Antigens, Surface; Calcium; Carcinogens; Carrier Proteins; Cell Adhesion Molecules; Cell Communication; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cyclic AMP; Diterpenes; Humans; Intercellular Junctions; Mice; Mice, Inbred BALB C; Permeability; Phorbol Esters; Phospholipids; Protein Kinases; Sodium-Hydrogen Exchangers; Sodium-Potassium-Exchanging ATPase; Terpenes; Tetradecanoylphorbol Acetate | 1985 |
Cellular and viral fos genes: structure, regulation of expression and biological properties of their encoded products.
Topics: Amino Acid Sequence; Animals; Base Sequence; Bone Neoplasms; Cell Differentiation; Cell Division; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Cell Transformation, Viral; Fibroblasts; Gene Expression Regulation; Gene Products, gag; Hematopoiesis; Humans; Leukemia, Myeloid, Acute; Male; Mice; Oncogenes; Osteosarcoma; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogenes; Rats; Retroviridae Proteins; Sarcoma Viruses, Murine; Teratoma; Tetradecanoylphorbol Acetate | 1986 |
Molecular mechanisms of induction of transcription of beta-actin gene by tumour promoters and serum factors.
Topics: Actins; Animals; Carcinogens; Cell Transformation, Neoplastic; Gene Expression Regulation; Mice; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transforming Growth Factors | 1988 |
The origins of human cancer: molecular mechanisms of carcinogenesis and their implications for cancer prevention and treatment--twenty-seventh G.H.A. Clowes memorial award lecture.
Topics: Carcinogens; Cell Transformation, Neoplastic; DNA; Environmental Exposure; Gene Amplification; Humans; Models, Biological; Neoplasms; Oncogenes; Polycyclic Compounds; Protein Kinase C; Tetradecanoylphorbol Acetate | 1988 |
[Biophysics of the neoplastic process].
Topics: Animals; Carcinogens; Carcinogens, Environmental; Cell Transformation, Neoplastic; Colonic Neoplasms; DNA; Free Radicals; Humans; Neoplasms, Experimental; Peptide Chain Termination, Translational; Smoking; Tetradecanoylphorbol Acetate | 1986 |
Control of cell differentiation and cell transformation in vitro by phorbol 12-myristate 13-acetate and 1 alpha,25-dihydroxyvitamin D3.
Topics: Animals; Calcitriol; Carcinogens; Cell Differentiation; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Esterases; Humans; Lyngbya Toxins; Macrophages; Muramidase; Phorbols; Tetradecanoylphorbol Acetate | 1985 |
Transient induction of c-fos and c-myc in an immediate consequence of growth factor stimulation.
Topics: Animals; Blood; Calcimycin; Cell Line; Cell Transformation, Neoplastic; Colony-Stimulating Factors; Gene Expression Regulation; Growth Substances; Humans; Leukemia, Myeloid, Acute; Macrophages; Proto-Oncogenes; RNA, Messenger; Tetradecanoylphorbol Acetate | 1985 |
891 other study(ies) available for tetradecanoylphorbol acetate and Cell Transformation, Neoplastic
Article | Year |
---|---|
Nfe2l2 Regulates Metabolic Rewiring and Epigenetic Reprogramming in Mediating Cancer Protective Effect by Fucoxanthin.
Topics: Animals; Antioxidants; Cell Line; Cell Transformation, Neoplastic; Epigenesis, Genetic; Gene Expression Regulation; Gene Knockdown Techniques; Mice; NF-E2-Related Factor 2; Oxidation-Reduction; Reactive Oxygen Species; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Xanthophylls | 2022 |
Gene Expression over Time during Cell Transformation Due to Non-Genotoxic Carcinogen Treatment of Bhas 42 Cells.
Topics: Animals; BALB 3T3 Cells; Butylated Hydroxyanisole; Carcinogenicity Tests; Carcinogens; Cell Transformation, Neoplastic; Gene Expression; Mice; Tetradecanoylphorbol Acetate | 2022 |
DNA Methylome and Transcriptome Study of Triterpenoid CDDO in TPA-Mediated Skin Carcinogenesis Model.
Topics: Cell Transformation, Neoplastic; Epigenome; Humans; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcriptome; Triterpenes; Ultraviolet Rays | 2022 |
Keratinocyte Regnase-1, a Downregulator of Skin Inflammation, Contributes to Protection against Tumor Promotion by Limiting Cyclooxygenase-2 Expression.
Topics: Acetates; Animals; Carcinogenesis; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cyclooxygenase 2; Dermatitis; Humans; Inflammation; Keratinocytes; Lithostathine; Mice; RNA, Messenger; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2023 |
Can a 12-gene expression signature predict the cell transforming potential of tumor promoting agents in Bhas 42 cells?
Topics: Animals; BALB 3T3 Cells; Butylated Hydroxyanisole; Carcinogenicity Tests; Carcinogens; Cell Transformation, Neoplastic; Cholic Acid; Mice; Quercetin; Reproducibility of Results; Tetradecanoylphorbol Acetate; Transcriptome | 2023 |
Triterpenoid corosolic acid modulates global CpG methylation and transcriptome of tumor promotor TPA induced mouse epidermal JB6 P+ cells.
Topics: Animals; Carcinogens; Cell Line; Cell Survival; Cell Transformation, Neoplastic; CpG Islands; DNA Methylation; Epidermal Cells; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Mice; Phytochemicals; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcriptome; Triterpenes | 2020 |
Integrin α3β1 Is a Key Regulator of Several Protumorigenic Pathways during Skin Carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Adhesion; Cell Adhesion Molecules; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Epidermis; Humans; Integrin alpha3beta1; Kalinin; Keratinocytes; Mice; Neoplasms, Experimental; Signal Transduction; Skin Neoplasms; Spheroids, Cellular; Tetradecanoylphorbol Acetate; Tetraspanin 24 | 2021 |
12-O-Tetradecanoylphorbol-13-acetate (TPA) is anti-tumorigenic in liver cancer cells via inhibiting YAP through AMOT.
Topics: Angiomotins; Animals; Antineoplastic Agents; Caspase 3; Caspase 7; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Disease Models, Animal; Gene Expression; Heterografts; Humans; Intercellular Signaling Peptides and Proteins; Liver Neoplasms; Membrane Proteins; Mice; Microfilament Proteins; Nuclear Proteins; Phenotype; Protein Transport; Tetradecanoylphorbol Acetate; Transcription Factors | 2017 |
Targeted disruption of TC-PTP in the proliferative compartment augments STAT3 and AKT signaling and skin tumor development.
Topics: Alleles; Animals; Apoptosis; Cell Proliferation; Cell Transformation, Neoplastic; Disease Models, Animal; Epidermis; Gene Knockout Techniques; Gene Targeting; Hyperplasia; Keratinocytes; Mice; Mice, Knockout; Organ Specificity; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 2; Proto-Oncogene Proteins c-akt; Signal Transduction; Skin Neoplasms; STAT3 Transcription Factor; Tetradecanoylphorbol Acetate | 2017 |
E1a is an exogenous in vivo tumour suppressor.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenovirus E1A Proteins; Animals; Cell Proliferation; Cell Transformation, Neoplastic; Female; HCT116 Cells; Humans; Melanoma, Experimental; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Nude; Mice, Transgenic; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Transfection; Tumor Burden; Tumor Suppressor Proteins | 2017 |
Red Ginseng Oil Inhibits TPA-Induced Transformation of Skin Epidermal JB6 Cells.
Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Cell Line; Cell Transformation, Neoplastic; Cyclins; Cyclooxygenase 2; Epidermis; Extracellular Signal-Regulated MAP Kinases; Glycogen Synthase Kinases; Heme Oxygenase-1; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Mice; NF-E2-Related Factor 2; NF-kappa B; Panax; Plant Oils; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factor AP-1 | 2018 |
Lead facilitates foci formation in a Balb/c-3T3 two-step cell transformation model: role of Ape1 function.
Topics: Animals; BALB 3T3 Cells; Carcinogens, Environmental; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Comet Assay; DNA Damage; DNA-(Apurinic or Apyrimidinic Site) Lyase; Gene Expression; Humans; Lead; Methylnitronitrosoguanidine; Mice; Models, Biological; Tetradecanoylphorbol Acetate | 2018 |
Fucoxanthin Elicits Epigenetic Modifications, Nrf2 Activation and Blocking Transformation in Mouse Skin JB6 P+ Cells.
Topics: Animals; Antioxidant Response Elements; Cell Transformation, Neoplastic; CpG Islands; DNA Demethylation; Epidermal Cells; Epigenesis, Genetic; Gene Knockdown Techniques; Hep G2 Cells; Humans; Mice; NF-E2-Related Factor 2; RNA, Small Interfering; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Xanthophylls | 2018 |
Multicolour lineage tracing reveals clonal dynamics of squamous carcinoma evolution from initiation to metastasis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cell Lineage; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Clonal Evolution; Epithelial Cells; Female; Gene Expression Regulation, Neoplastic; Genes, ras; Genetic Predisposition to Disease; Male; Mice, Transgenic; Mutation; Neoplasms, Experimental; Phenotype; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Tumor Burden | 2018 |
TRP63/TP63 loss accelerates skin tumorigenesis through activation of Wnt/β-catenin signaling.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cell Differentiation; Cell Line; Cell Proliferation; Cell Transformation, Neoplastic; Gene Expression Regulation, Neoplastic; Genetic Predisposition to Disease; Humans; Mice, Knockout; Mice, Nude; Phosphoproteins; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Trans-Activators; Transcription Factors; Tumor Burden; Tumor Suppressor Proteins; Wnt Signaling Pathway | 2018 |
Xiao Tan He Wei Decoction reverses MNNG-induced precancerous lesions of gastric carcinoma in vivo and vitro: Regulation of apoptosis through NF-κB pathway.
Topics: Animals; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Disease Models, Animal; Drugs, Chinese Herbal; Epithelial-Mesenchymal Transition; Humans; Hyperplasia; Methylnitronitrosoguanidine; NF-kappa B; Precancerous Conditions; Rats, Wistar; Stomach Neoplasms; Tetradecanoylphorbol Acetate | 2018 |
C/EBPβ deletion in oncogenic Ras skin tumors is a synthetic lethal event.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; CCAAT-Enhancer-Binding Protein-beta; Cell Differentiation; Cell Transformation, Neoplastic; Gene Expression Regulation, Neoplastic; Genes, Lethal; Keratinocytes; Mice; Mice, Knockout; ras Proteins; Receptors, Death Domain; Signal Transduction; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53 | 2018 |
Bone marrow-derived epithelial cells and hair follicle stem cells contribute to development of chronic cutaneous neoplasms.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bone Marrow Cells; Bone Marrow Transplantation; Bone Morphogenetic Protein 5; Cell Movement; Cell Plasticity; Cell Transformation, Neoplastic; Coculture Techniques; Epithelial Cells; Female; Hair Follicle; HMGB1 Protein; Keratinocytes; Keratins; Male; Mice; Mice, Inbred C57BL; Neoplasm Invasiveness; Papilloma; Skin Neoplasms; Stem Cells; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2018 |
[Role of clock proteins in skin carcinogenesis in 14-month-old SHR mice maintained under disrupted light regimen].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; ARNTL Transcription Factors; Cell Transformation, Neoplastic; CLOCK Proteins; Cryptochromes; Gene Expression Regulation, Neoplastic; Lighting; Male; Mice; Neoplasm Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2016 |
CpG methyl-seq and RNA-seq epigenomic and transcriptomic studies on the preventive effects of Moringa isothiocyanate in mouse epidermal JB6 cells induced by the tumor promoter TPA.
Topics: Animals; Anticarcinogenic Agents; Carcinogens; Cell Line; Cell Transformation, Neoplastic; CpG Islands; DNA Methylation; Epidermal Cells; Epigenome; Isothiocyanates; Mice; Moringa; Sequence Analysis, RNA; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2019 |
Altered prostanoid signaling contributes to increased skin tumorigenesis in Tpl2 knockout mice.
Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Female; Gene Deletion; Gene Expression Regulation, Neoplastic; Keratinocytes; Male; MAP Kinase Kinase Kinases; Mice; Mice, Inbred C57BL; Prostaglandins; Proto-Oncogene Proteins; Receptors, Prostaglandin; Signal Transduction; Skin; Tetradecanoylphorbol Acetate | 2013 |
Dysregulation of pathways involved in the processing of cancer and microenvironment information in MCA + TPA transformed C3H/10T1/2 cells.
Topics: Animals; Carcinogens; Cell Line, Transformed; Cell Transformation, Neoplastic; Methylcholanthrene; Mice; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Microenvironment | 2013 |
Mule/Huwe1/Arf-BP1 suppresses Ras-driven tumorigenesis by preventing c-Myc/Miz1-mediated down-regulation of p21 and p15.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p15; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p21; Down-Regulation; Female; Genes, ras; Keratinocytes; Male; Mice; Mice, Knockout; Nuclear Proteins; Oncogene Protein p21(ras); Protein Inhibitors of Activated STAT; Proto-Oncogene Proteins c-myc; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Ubiquitin-Protein Ligases | 2013 |
Modulatory effects of Azadirachta indica leaf extract on cutaneous and hepatic biochemical status during promotion phase of DMBA/TPA-induced skin tumorigenesis in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Antioxidants; Azadirachta; Cell Transformation, Neoplastic; Cytochrome P-450 Enzyme System; Cytochromes b5; Gene Expression Regulation, Neoplastic; Glutathione Transferase; Lipid Peroxidation; Liver; Male; Mice; Micronucleus Tests; Neoplasms, Experimental; Phytotherapy; Plant Extracts; Plant Leaves; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Xenobiotics | 2013 |
Fermented Prunus mume with probiotics inhibits 7,12-dimethylbenz[a]anthracene and 12-o-tetradecanoyl phorbol-13-acetate induced skin carcinogenesis through alleviation of oxidative stress.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Antioxidants; Cell Proliferation; Cell Transformation, Neoplastic; Diet; Female; Fermentation; Lipid Peroxidation; Mice; Mice, Inbred BALB C; Oxidative Stress; Plant Preparations; Probiotics; Prunus; Skin; Skin Neoplasms; Superoxide Dismutase; Tetradecanoylphorbol Acetate | 2013 |
The effects of dissociated glucocorticoids RU24858 and RU24782 on TPA-induced skin tumor promotion biomarkers in SENCAR mice.
Topics: Animals; Animals, Outbred Strains; Anticarcinogenic Agents; Biomarkers; Cell Proliferation; Cell Transformation, Neoplastic; Cyclooxygenase 2; Desoximetasone; Epidermis; Female; Gene Expression Regulation; Glucocorticoids; Hyperplasia; Interleukin-6; Mice; Nitric Oxide Synthase Type II; Proto-Oncogene Proteins c-jun; RNA, Messenger; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2014 |
S100A14: novel modulator of terminal differentiation in esophageal cancer.
Topics: Calcium; Calcium-Binding Proteins; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Filaggrin Proteins; G1 Phase Cell Cycle Checkpoints; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Intermediate Filament Proteins; Neoplasm Grading; Neoplasm Staging; Protein Precursors; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription Factors | 2013 |
Impact of mTORC1 inhibition on keratinocyte proliferation during skin tumor promotion in wild-type and BK5.AktWT mice.
Topics: Animals; Antibiotics, Antineoplastic; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Chromones; ErbB Receptors; Female; Flavonoids; Hair Follicle; Hyperplasia; Keratinocytes; Male; Mechanistic Target of Rapamycin Complex 1; Mice; Mice, Inbred ICR; Mice, Transgenic; Morpholines; Multiprotein Complexes; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Proto-Oncogene Proteins c-akt; Signal Transduction; Sirolimus; Skin Neoplasms; Tetradecanoylphorbol Acetate; TOR Serine-Threonine Kinases | 2014 |
Genome-wide screening of aberrant DNA methylation which associated with gene expression in mouse skin cancers.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Azacitidine; Cell Line, Tumor; Cell Transformation, Neoplastic; DNA Methylation; Enzyme Inhibitors; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Mice, Inbred C57BL; Papilloma; Promoter Regions, Genetic; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factor AP-2 | 2015 |
A derivative of chrysin suppresses two-stage skin carcinogenesis by inhibiting mitogen- and stress-activated kinase 1.
Topics: Animals; Anticarcinogenic Agents; Cell Cycle; Cell Proliferation; Cell Transformation, Neoplastic; Flavones; Flavonoids; Histones; Male; Mice; p38 Mitogen-Activated Protein Kinases; Papilloma; Phenethylamines; Phosphorylation; Protein Structure, Tertiary; Ribosomal Protein S6 Kinases, 90-kDa; Signal Transduction; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2014 |
Silibinin inhibits tumor promotional triggers and tumorigenesis against chemically induced two-stage skin carcinogenesis in Swiss albino mice: possible role of oxidative stress and inflammation.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Carcinogenesis; Catalase; Cell Transformation, Neoplastic; Chemoprevention; Cyclooxygenase 2; Down-Regulation; Female; Glucosephosphate Dehydrogenase; Inflammation; Interleukin-1beta; Interleukin-6; Lipid Peroxidation; Mice; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidative Stress; Silybin; Silymarin; Skin; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Up-Regulation; Vascular Endothelial Growth Factor A | 2014 |
Selective proliferation of normal human melanocytes in vitro in the presence of phorbol ester and cholera toxin by Eisinger and Marko.
Topics: Cell Culture Techniques; Cell Proliferation; Cell Transformation, Neoplastic; Cholera Toxin; Culture Media; Dermatology; History, 20th Century; Humans; Melanocytes; Tetradecanoylphorbol Acetate | 2014 |
S100A9 has a protective role in inflammation-induced skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Calgranulin A; Calgranulin B; Carcinogenesis; Cell Transformation, Neoplastic; Dimerization; Female; Gene Deletion; Gene Expression Regulation, Neoplastic; Inflammation; Keratinocytes; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neutrophils; Skin Neoplasms; T-Lymphocytes; Tetradecanoylphorbol Acetate | 2014 |
Requirement and epigenetics reprogramming of Nrf2 in suppression of tumor promoter TPA-induced mouse skin cell transformation by sulforaphane.
Topics: Animals; Anticarcinogenic Agents; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Isothiocyanates; Mice; NF-E2-Related Factor 2; Skin Neoplasms; Sulfoxides; Tetradecanoylphorbol Acetate | 2014 |
A novel mechanism of skin tumor promotion involving interferon-gamma (IFNγ)/signal transducer and activator of transcription-1 (Stat1) signaling.
Topics: Animals; Anthracenes; Cell Transformation, Neoplastic; Cells, Cultured; Female; Humans; Interferon Regulatory Factor-1; Interferon-gamma; Keratinocytes; Mice; Neoplasms, Experimental; Phosphorylation; Signal Transduction; Skin Neoplasms; STAT1 Transcription Factor; Tetradecanoylphorbol Acetate | 2015 |
Targeted deletion of RasGRP1 impairs skin tumorigenesis.
Topics: Animals; Cell Transformation, Neoplastic; Codon; Gene Deletion; Gene Targeting; Genes, ras; Guanine Nucleotide Exchange Factors; Hyperplasia; Mice; Mice, Knockout; Mutation; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcriptional Activation | 2014 |
Tumor promoter-induced sulfiredoxin is required for mouse skin tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Cell Line; Cell Proliferation; Cell Transformation, Neoplastic; Disease Models, Animal; Gene Expression Regulation; JNK Mitogen-Activated Protein Kinases; Mice; Mice, Knockout; Mitogen-Activated Protein Kinases; Oxidation-Reduction; Oxidoreductases Acting on Sulfur Group Donors; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcriptional Activation | 2014 |
Epidermal barrier defects link atopic dermatitis with altered skin cancer susceptibility.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cell Communication; Cell Differentiation; Cell Transformation, Neoplastic; Cytokines; Dermatitis, Atopic; Disease Models, Animal; Epidermis; Keratinocytes; Membrane Proteins; Mice, 129 Strain; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Mice, Nude; NK Cell Lectin-Like Receptor Subfamily K; Papilloma; Permeability; Plakins; Protein Precursors; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Thymic Stromal Lymphopoietin; Time Factors | 2014 |
Meis1 regulates epidermal stem cells and is required for skin tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adult Stem Cells; Animals; Carcinogens; Carcinoma; Cell Differentiation; Cell Proliferation; Cell Transformation, Neoplastic; Disease Progression; Gene Expression Regulation, Neoplastic; Hair Follicle; Homeodomain Proteins; Keratinocytes; Mice; Mice, Transgenic; Multipotent Stem Cells; Myeloid Ecotropic Viral Integration Site 1 Protein; Neoplasm Proteins; Papilloma; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2014 |
Carcinogenic potential of metal nanoparticles in BALB/3T3 cell transformation assay.
Topics: 3T3 Cells; Animals; Carcinogens; Cell Survival; Cell Transformation, Neoplastic; Cerium; Ferrosoferric Oxide; Gold; Metal Nanoparticles; Methylcholanthrene; Mice; Mice, Inbred BALB C; Microscopy, Electron; Tetradecanoylphorbol Acetate | 2016 |
Comparison of the inhibitory effects of delphinidin and its glycosides on cell transformation.
Topics: Animals; Anthocyanins; Cell Line; Cell Transformation, Neoplastic; Drug Evaluation, Preclinical; Glucosides; MAP Kinase Kinase 1; Mice; Models, Molecular; Molecular Structure; Phosphorylation; Quartz Crystal Microbalance Techniques; Tetradecanoylphorbol Acetate | 2015 |
Immature myeloid cells directly contribute to skin tumor development by recruiting IL-17-producing CD4+ T cells.
Topics: Animals; Calgranulin B; CD4-Positive T-Lymphocytes; Cell Transformation, Neoplastic; Chemokine CCL4; Colitis; Female; Humans; Mice, Transgenic; Myeloid Cells; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2015 |
Conditional disruption of rictor demonstrates a direct requirement for mTORC2 in skin tumor development and continued growth of established tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogens; Carrier Proteins; Caspase 3; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; Chemoprevention; Keratinocytes; Mechanistic Target of Rapamycin Complex 2; Mice; Mice, Inbred C57BL; Mice, Transgenic; Multiprotein Complexes; Proto-Oncogene Proteins c-akt; Rapamycin-Insensitive Companion of mTOR Protein; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; TOR Serine-Threonine Kinases; Ultraviolet Rays | 2015 |
Keratinocyte p38δ loss inhibits Ras-induced tumor formation, while systemic p38δ loss enhances skin inflammation in the early phase of chemical carcinogenesis in mouse skin.
Topics: Animals; Benz(a)Anthracenes; Cell Transformation, Neoplastic; Inflammation; Mice; Mice, Nude; Mitogen-Activated Protein Kinase 13; ras Proteins; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2016 |
Dehydroglyasperin C suppresses TPA-induced cell transformation through direct inhibition of MKK4 and PI3K.
Topics: Animals; Benzopyrans; Carcinogens; Cell Line; Cell Line, Tumor; Cell Survival; Cell Transformation, Neoplastic; Cyclooxygenase 2; Gene Expression Regulation, Neoplastic; Humans; MAP Kinase Kinase 4; Mice; NF-kappa B; Phosphatidylinositol 3-Kinases; Protein Binding; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factor AP-1 | 2016 |
Notch1 Activation or Loss Promotes HPV-Induced Oral Tumorigenesis.
Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Carcinogens; Carcinoma, Verrucous; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cocarcinogenesis; Disease Progression; DNA Transposable Elements; Female; Humans; Mice; Mice, Transgenic; Mouth Neoplasms; Mutagenesis, Insertional; Neoplasm Invasiveness; Oncogenes; Papilloma; Papillomaviridae; Receptor, Notch1; Skin Neoplasms; Specific Pathogen-Free Organisms; Tamoxifen; Tetradecanoylphorbol Acetate; Tumor Virus Infections; Uterine Cervical Neoplasms | 2015 |
Low dose triterpene-quinone fraction from Ardisia crispa root precludes chemical-induced mouse skin tumor promotion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Anticarcinogenic Agents; Ardisia; Cell Transformation, Neoplastic; Chemical Fractionation; Chemoprevention; Curcumin; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Male; Mice; Mice, Inbred ICR; Plant Extracts; Plant Roots; Quinones; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Triterpenes | 2015 |
Fractionation of a tumor-initiating UV dose introduces DNA damage-retaining cells in hairless mouse skin and renders subsequent TPA-promoted tumors non-regressing.
Topics: Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; DNA Damage; Epidermis; Female; Hyperplasia; Immunoenzyme Techniques; Male; Mice; Mice, Hairless; Mutation; Real-Time Polymerase Chain Reaction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53; Ultraviolet Rays | 2016 |
Epigenetic blockade of neoplastic transformation by bromodomain and extra-terminal (BET) domain protein inhibitor JQ-1.
Topics: Acetylation; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Azepines; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Cyclooxygenase 2; E1A-Associated p300 Protein; Epidermis; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Genes, Reporter; Histones; Humans; Mice; Nuclear Proteins; Promoter Regions, Genetic; Protein Processing, Post-Translational; RNA Interference; Tetradecanoylphorbol Acetate; Transcription Factors; Triazoles | 2016 |
Lgr4 is crucial for skin carcinogenesis by regulating MEK/ERK and Wnt/β-catenin signaling pathways.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Cyclin D1; Extracellular Signal-Regulated MAP Kinases; Genetic Predisposition to Disease; Humans; Keratinocytes; MAP Kinase Kinase 1; Mice, Knockout; Neoplasms, Experimental; Papilloma; Phenotype; Receptors, G-Protein-Coupled; RNA Interference; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Transcription Factor AP-1; Transfection; Wnt Signaling Pathway | 2016 |
Elevated ΔNp63α Levels Facilitate Epidermal and Biliary Oncogenic Transformation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bile Duct Neoplasms; Cell Transformation, Neoplastic; Cells, Cultured; Cellular Senescence; Hyperplasia; Mice; Mice, Inbred C57BL; Mice, Transgenic; Phosphoproteins; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Trans-Activators | 2017 |
Suppression of skin tumorigenesis in CD109-deficient mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, CD; Apoptosis; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; DNA Damage; Genes, ras; Genetic Predisposition to Disease; Keratinocytes; Mice, Knockout; Mutation; Neoplasm Proteins; NF-E2-Related Factor 2; Papilloma; Phenotype; Phosphorylation; Signal Transduction; Skin Neoplasms; Smad2 Protein; Tetradecanoylphorbol Acetate; Time Factors; Transforming Growth Factor beta1 | 2016 |
Involvement of the antioxidative property of morusin in blocking phorbol ester-induced malignant transformation of JB6 P
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Carcinogens; Cell Line; Cell Movement; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Cyclooxygenase 2; Epidermal Cells; Epidermis; Flavonoids; Mice; Mice, Inbred BALB C; NF-kappa B; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Transcription Factor AP-1 | 2017 |
The resveratrol analogue 3,5,3',4',5'-pentahydroxy-trans-stilbene inhibits cell transformation via MEK.
Topics: Adenosine Triphosphate; Animals; Cell Line; Cell Transformation, Neoplastic; Extracellular Signal-Regulated MAP Kinases; Mice; Mitogen-Activated Protein Kinase Kinases; Models, Molecular; Molecular Structure; Phosphorylation; Promoter Regions, Genetic; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-raf; Resveratrol; Ribosomal Protein S6 Kinases, 90-kDa; Stilbenes; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcriptional Activation | 2008 |
Ligand activation of peroxisome proliferator-activated receptor beta/delta (PPAR beta/delta) inhibits chemically induced skin tumorigenesis.
Topics: Acetone; Animals; Carcinogens; Cell Differentiation; Cell Proliferation; Cell Transformation, Neoplastic; Enzyme Activation; Female; Keratinocytes; Ligands; Mice; Mice, Mutant Strains; PPAR delta; PPAR-beta; Skin Neoplasms; Tetradecanoylphorbol Acetate; Thiazoles | 2008 |
Promotion of mouse two-stage skin carcinogenesis by diacylglycerol-rich edible oil.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Diglycerides; Fatty Acids; Female; Fluocinolone Acetonide; Linoleic Acid; Mice; Oils; Oleic Acid; Protein Kinase C; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2009 |
A novel Src kinase inhibitor reduces tumour formation in a skin carcinogenesis model.
Topics: Adult; Aged; Animals; Anticarcinogenic Agents; Benzodioxoles; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Disease Models, Animal; Female; Humans; Keratinocytes; Keratosis; Male; Mice; Middle Aged; Papilloma; Precancerous Conditions; Quinazolines; Skin Neoplasms; src-Family Kinases; Tetradecanoylphorbol Acetate | 2009 |
Inducible cutaneous inflammation reveals a protumorigenic role for keratinocyte CXCR2 in skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Drug Eruptions; Enzyme Activation; Female; Hair Follicle; HeLa Cells; Humans; Keratinocytes; Ligands; Male; Mice; Neutrophils; Protein Kinase C-alpha; Receptors, Interleukin-8B; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2009 |
Transient receptor potential type vanilloid 1 suppresses skin carcinogenesis.
Topics: Animals; Carcinogens; Cell Line, Tumor; Cell Transformation, Neoplastic; Down-Regulation; ErbB Receptors; Lysosomes; Mice; Mice, Knockout; Protein Structure, Tertiary; Proto-Oncogene Proteins c-cbl; Skin Neoplasms; Tetradecanoylphorbol Acetate; TRPV Cation Channels; Ubiquitin | 2009 |
The coactivator CRTC1 promotes cell proliferation and transformation via AP-1.
Topics: Cell Proliferation; Cell Transformation, Neoplastic; DNA-Binding Proteins; HeLa Cells; Humans; Immunoprecipitation; Nuclear Proteins; Promoter Regions, Genetic; Proto-Oncogene Mas; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Tetradecanoylphorbol Acetate; Trans-Activators; Transcription Factor AP-1; Transcription Factors; Transcriptional Activation | 2009 |
Selective role for Mek1 but not Mek2 in the induction of epidermal neoplasia.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Differentiation; Cell Transformation, Neoplastic; Genotype; Hyperplasia; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Mice; Mice, Knockout; Mice, Transgenic; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Oncogene Protein v-akt; Papilloma; Phosphorylation; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2009 |
Linoleic acid metabolite suppresses skin inflammation and tumor promotion in mice: possible roles of programmed cell death 4 induction.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Apoptosis Regulatory Proteins; Cell Transformation, Neoplastic; Dermatitis; Extracellular Signal-Regulated MAP Kinases; Fatty Acids, Unsaturated; Female; Linoleic Acid; Lipopolysaccharides; Mice; Mice, Inbred ICR; RNA-Binding Proteins; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Tumor Suppressor Proteins | 2009 |
Identification of the B-Raf/Mek/Erk MAP kinase pathway as a target for all-trans retinoic acid during skin cancer promotion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Blotting, Western; Carcinogens; Cell Transformation, Neoplastic; Extracellular Signal-Regulated MAP Kinases; Female; Gene Expression; Immunohistochemistry; MAP Kinase Kinase Kinases; Mice; Oligonucleotide Array Sequence Analysis; Proto-Oncogene Proteins B-raf; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin | 2009 |
A regulatory mechanism for RSK2 NH(2)-terminal kinase activity.
Topics: Binding Sites; Cell Division; Cell Line, Tumor; Cell Transformation, Neoplastic; Epidermal Growth Factor; Humans; Kaempferols; Kinetics; Lysine; Neoplasms; Phosphorylation; Protein Kinases; Recombinant Proteins; Reference Values; Ribosomal Protein S6 Kinases, 90-kDa; Skin; Tetradecanoylphorbol Acetate; Tissue Array Analysis; Valine | 2009 |
SirT1-null mice develop tumors at normal rates but are poorly protected by resveratrol.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Angiogenesis Inhibitors; Animals; Blood Vessels; Carcinogens; Cell Transformation, Neoplastic; Female; Genotype; Immunohistochemistry; Intestinal Polyps; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Knockout; Neoplasms, Experimental; NIH 3T3 Cells; Resveratrol; Sirtuin 1; Sirtuins; Skin Neoplasms; Stilbenes; Tetradecanoylphorbol Acetate; Transfection | 2009 |
Photodynamic therapy with 5-aminolevulinic acid and diamino acid derivatives of protoporphyrin IX reduces papillomas in mice without eliminating transformation into squamous cell carcinoma of the skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aminolevulinic Acid; Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Kaplan-Meier Estimate; Mice; Mice, Inbred Strains; Papilloma; Photochemotherapy; Photosensitizing Agents; Protoporphyrins; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2009 |
Cellular dichotomy between anchorage-independent growth responses to bFGF and TPA reflects molecular switch in commitment to carcinogenesis.
Topics: Animals; Base Sequence; Basic-Leucine Zipper Transcription Factors; Cell Adhesion; Cell Division; Cell Line, Tumor; Cell Transformation, Neoplastic; DNA Primers; DNA-Binding Proteins; Fibroblast Growth Factor 2; Humans; Mice; Oligonucleotide Array Sequence Analysis; Tetradecanoylphorbol Acetate; Transcription Factors; Transcription, Genetic | 2009 |
T-box-expressed-in-T-cells (T-bet) expression by the tumor cells of hairy-cell leukemia correlates with interferon-gamma production.
Topics: Antigens, CD; Antigens, CD19; Antigens, Neoplasm; B-Lymphocyte Subsets; Cell Transformation, Neoplastic; Cells, Cultured; Cytokines; Enterotoxins; Gene Expression Regulation, Leukemic; Humans; Immunophenotyping; Integrin alpha Chains; Interferon-gamma; Ionomycin; Leukemia, Hairy Cell; Neoplasm Proteins; T-Box Domain Proteins; T-Lymphocytes; Tetradecanoylphorbol Acetate | 2009 |
All-trans retinoic acid suppresses Stat3 signaling during skin carcinogenesis.
Topics: Animals; Antineoplastic Agents; Blotting, Western; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Extracellular Signal-Regulated MAP Kinases; Female; Immunohistochemistry; MAP Kinase Kinase Kinases; Mice; Mice, Inbred SENCAR; Mice, Transgenic; raf Kinases; Signal Transduction; Skin Neoplasms; STAT3 Transcription Factor; Tetradecanoylphorbol Acetate; Tretinoin | 2009 |
Piceatannol inhibits phorbol ester-induced NF-kappa B activation and COX-2 expression in cultured human mammary epithelial cells.
Topics: Anti-Inflammatory Agents; Antioxidants; Breast; Breast Neoplasms; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Cyclooxygenase 2; DNA-Binding Proteins; Dose-Response Relationship, Drug; Down-Regulation; Epithelial Cells; Female; Humans; I-kappa B Kinase; NF-kappa B; Phosphorylation; Protein Transport; Stilbenes; Tetradecanoylphorbol Acetate | 2009 |
Transforming growth factor beta1 enhances tumor promotion in mouse skin carcinogenesis.
Topics: Animals; Carcinogens; Cell Proliferation; Cell Transformation, Neoplastic; Mice; Mice, Inbred BALB C; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta1 | 2010 |
Anti-tumor-initiating effects of spiro-biflavonoids from Abies sachalinensis.
Topics: Abies; Animals; Anticarcinogenic Agents; Biflavonoids; Carcinogenicity Tests; Cell Transformation, Neoplastic; Cells, Cultured; Cocarcinogenesis; Female; Humans; Mice; Mice, Inbred ICR; Molecular Structure; Peroxynitrous Acid; Plant Bark; Skin Neoplasms; Spiro Compounds; Tetradecanoylphorbol Acetate | 2010 |
Loss of tumor progression locus 2 (tpl2) enhances tumorigenesis and inflammation in two-stage skin carcinogenesis.
Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Cytokines; Female; Immunoblotting; Immunohistochemistry; Inflammation; Male; MAP Kinase Kinase Kinases; Mice; Mice, Inbred C57BL; Mice, Transgenic; Proto-Oncogene Proteins; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2011 |
Dual function of MyD88 in RAS signaling and inflammation, leading to mouse and human cell transformation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Cycle; Cell Transformation, Neoplastic; Extracellular Signal-Regulated MAP Kinases; Humans; Inflammation; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Myeloid Differentiation Factor 88; Phosphorylation; ras Proteins; Signal Transduction; Tetradecanoylphorbol Acetate | 2010 |
Intrinsic cooperation between p16INK4a and p21Waf1/Cip1 in the onset of cellular senescence and tumor suppression in vivo.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Blotting, Western; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p15; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p21; Embryo, Mammalian; Fibroblasts; Histones; Mice; Mice, Inbred C57BL; Mice, Knockout; Octamer Transcription Factor-3; ras Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2010 |
IL-17 enhances tumor development in carcinogen-induced skin cancer.
Topics: Aniline Compounds; Animals; Carcinogens; CD11b Antigen; Cell Growth Processes; Cell Transformation, Neoplastic; Gene Expression Regulation, Neoplastic; Interferon-gamma; Interleukin-17; Mice; Mice, Inbred C57BL; Mice, Knockout; Skin; Skin Neoplasms; STAT3 Transcription Factor; Tetradecanoylphorbol Acetate; Tumor Microenvironment | 2010 |
p-HPEA-EDA, a phenolic compound of virgin olive oil, activates AMP-activated protein kinase to inhibit carcinogenesis.
Topics: Aldehydes; AMP-Activated Protein Kinases; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Survival; Cell Transformation, Neoplastic; Cyclooxygenase 2; Cyclopentane Monoterpenes; Enzyme Activation; Humans; Olive Oil; Phenols; Plant Oils; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53 | 2011 |
FSP1+ fibroblasts promote skin carcinogenesis by maintaining MCP-1-mediated macrophage infiltration and chronic inflammation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Proliferation; Cell Transformation, Neoplastic; Chemokine CCL2; Chronic Disease; Fibroblasts; Humans; Inflammation; Macrophages; Mice; Mice, Inbred BALB C; Mice, Transgenic; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2011 |
Evodiamine inhibits 12-O-tetradecanoylphorbol-13-acetate-induced activator protein 1 transactivation and cell transformation in human hepatocytes.
Topics: Antineoplastic Agents, Phytogenic; Cell Line; Cell Transformation, Neoplastic; Evodia; Extracellular Signal-Regulated MAP Kinases; Hepatocytes; Humans; Phosphorylation; Plant Extracts; Quinazolines; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcriptional Activation; Transfection | 2011 |
Inhibitory effects of Zuo-Jin-Wan and its alkaloidal ingredients on activator protein 1, nuclear factor-κB, and cellular transformation in HepG2 cells.
Topics: Antineoplastic Agents, Phytogenic; Berberine; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Coptis; Drugs, Chinese Herbal; Evodia; Hep G2 Cells; Humans; Liver Neoplasms; NF-kappa B; Plant Extracts; Quinazolines; Tetradecanoylphorbol Acetate; Transcription Factor AP-1 | 2011 |
5'-Nitro-indirubinoxime inhibits epidermal growth factor- and phorbol ester-induced AP-1 activity and cell transformation through inhibition of phosphorylation of Pin1.
Topics: Animals; Anticarcinogenic Agents; Cell Line; Cell Transformation, Neoplastic; Epidermal Growth Factor; Indoles; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinases; NIMA-Interacting Peptidylprolyl Isomerase; Oximes; Peptidylprolyl Isomerase; Phosphorylation; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-raf; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription, Genetic; Transcriptional Activation | 2011 |
Effects of psoralen from Psoralea corylifolia on quinone reductase, ornithine decarboxylase, and JB6 cells transformation promotion.
Topics: Animals; Anticarcinogenic Agents; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Enzyme Induction; Epidermal Cells; Epidermis; Ficusin; Inhibitory Concentration 50; Mice; NAD(P)H Dehydrogenase (Quinone); Ornithine Decarboxylase; Psoralea; Seeds; Tetradecanoylphorbol Acetate | 2011 |
Conjugates of 3α-methoxyserrat-14-en-21β-ol (PJ-1) and 3β-methoxyserrat-14-en-21β-ol (PJ-2) as cancer chemopreventive agents.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antigens, Viral; Carcinogenicity Tests; Cell Transformation, Neoplastic; Epstein-Barr Virus Infections; Flavanones; Genistein; Herpesvirus 4, Human; Hesperidin; Isoflavones; Mice; Oleanolic Acid; Skin Neoplasms; Tetradecanoylphorbol Acetate; Triterpenes | 2011 |
Loss of the miR-21 allele elevates the expression of its target genes and reduces tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogens; Cell Proliferation; Cell Transformation, Neoplastic; Epidermal Cells; Epidermis; Female; Gene Expression Regulation, Neoplastic; Keratinocytes; Mice; Mice, Knockout; MicroRNAs; ras Proteins; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2011 |
Enhancing mitochondrial respiration suppresses tumor promoter TPA-induced PKM2 expression and cell transformation in skin epidermal JB6 cells.
Topics: Animals; Cell Respiration; Cell Transformation, Neoplastic; Humans; Malates; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mitochondria; Protein Isoforms; Pyruvate Kinase; Pyruvic Acid; RNA, Small Interfering; Skin; Skin Neoplasms; Succinic Acid; Superoxide Dismutase; Tetradecanoylphorbol Acetate | 2011 |
CXCR3 enhances a T-cell-dependent epidermal proliferative response and promotes skin tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cell Proliferation; Cell Transformation, Neoplastic; Epidermis; Humans; Lymphocytes, Tumor-Infiltrating; Methylcholanthrene; Mice; Mice, Mutant Strains; Receptors, CXCR3; Skin Neoplasms; T-Lymphocytes; Tetradecanoylphorbol Acetate | 2011 |
Claudin-18 is an early-stage marker of pancreatic carcinogenesis.
Topics: Adenocarcinoma, Mucinous; Biomarkers, Tumor; Carcinoma, Pancreatic Ductal; Carcinoma, Papillary; Cell Transformation, Neoplastic; Claudins; Enzyme Inhibitors; Humans; Indoles; Maleimides; Membrane Proteins; Pancreas; Pancreatic Neoplasms; Pancreatitis, Chronic; Protein Kinase C; Retrospective Studies; Stomach Neoplasms; Tetradecanoylphorbol Acetate | 2011 |
Resveratrol and black tea polyphenol combination synergistically suppress mouse skin tumors growth by inhibition of activated MAPKs and p53.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Biomarkers, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Chemoprevention; Drug Screening Assays, Antitumor; Drug Synergism; Enzyme Activation; Male; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinases; Phosphorylation; Polyphenols; Proliferating Cell Nuclear Antigen; Protein Stability; Remission Induction; Resveratrol; Skin Neoplasms; Stilbenes; Tea; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53 | 2011 |
14-3-3σ and p63 play opposing roles in epidermal tumorigenesis.
Topics: 14-3-3 Proteins; 9,10-Dimethyl-1,2-benzanthracene; Animals; Blotting, Western; Carcinogens; Cell Differentiation; Cell Proliferation; Cell Transformation, Neoplastic; Gene Silencing; Homeostasis; Keratinocytes; Mice; Mice, Mutant Strains; Phosphoproteins; Polymerase Chain Reaction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Trans-Activators | 2011 |
Origin of ruffles: linkage to other protrusions, filopodia and lamellae.
Topics: Animals; Cell Line; Cell Shape; Cell Surface Extensions; Cell Transformation, Neoplastic; Epithelial Cells; Rats; Respiratory Mucosa; Signal Transduction; Tetradecanoylphorbol Acetate | 2012 |
Loss of Trop2 promotes carcinogenesis and features of epithelial to mesenchymal transition in squamous cell carcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Neoplasm; Carcinoma, Squamous Cell; Cell Adhesion Molecules; Cell Dedifferentiation; Cell Line, Tumor; Cell Transformation, Neoplastic; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Keratinocytes; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2011 |
Loss of the platelet activating factor receptor in mice augments PMA-induced inflammation and cutaneous chemical carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Inflammation; Mice; Mice, Inbred C57BL; Mice, Knockout; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled; Signal Transduction; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2012 |
Prostaglandin modulation of phorbol ester skin tumor promotion.
Topics: Animals; Arachidonic Acid; Carcinogens; Cell Transformation, Neoplastic; Cocarcinogenesis; Dinoprost; Dinoprostone; Female; Mice; Mice, Inbred SENCAR; Oxytocics; Papilloma; Prostaglandins; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1980 |
Cytotoxic activities and anti-tumor-promoting effects of microbial transformation products of prenylated chalcones from Angelica keiskei.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Angelica; Animals; Antigens, Viral; Antineoplastic Agents, Phytogenic; Apoptosis; Aspergillus; Carcinogenicity Tests; Carcinogens; Cell Transformation, Neoplastic; Chalcones; Humans; Mice; Molecular Structure; Prenylation; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2012 |
Cucurbitane triterpenoids from the leaves of Momordica charantia, and their cancer chemopreventive effects and cytotoxicities.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Viral; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinogens; Cell Transformation, Neoplastic; Glycosides; Humans; Mice; Molecular Structure; Momordica charantia; Plant Leaves; Skin Neoplasms; Tetradecanoylphorbol Acetate; Triterpenes; Tumor Cells, Cultured | 2012 |
MicroRNA-212 displays tumor-promoting properties in non-small cell lung cancer cells and targets the hedgehog pathway receptor PTCH1.
Topics: Antibodies, Monoclonal; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Gene Expression Regulation, Neoplastic; Hedgehog Proteins; Humans; Lung Neoplasms; MicroRNAs; Patched Receptors; Patched-1 Receptor; Receptors, Cell Surface; RNA Interference; RNA, Small Interfering; Signal Transduction; Tetradecanoylphorbol Acetate | 2012 |
A keratin 15 containing stem cell population from the hair follicle contributes to squamous papilloma development in the mouse.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Transformation, Neoplastic; Female; Genes, ras; Hair Follicle; Humans; Integrases; Keratin-15; Keratinocytes; Laser Capture Microdissection; Mice; Mice, Transgenic; Mutation; Papilloma; Skin; Skin Neoplasms; Stem Cells; Tetradecanoylphorbol Acetate | 2013 |
Deficiency of the Kruppel-like factor KLF4 correlates with increased cell proliferation and enhanced skin tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cell Adhesion; Cell Differentiation; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; Female; Gene Expression Regulation, Neoplastic; Humans; Keratinocytes; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Mice; Mice, Transgenic; RNA Interference; RNA, Small Interfering; Skin Neoplasms; Tamoxifen; Tetradecanoylphorbol Acetate | 2012 |
MicroRNA-29a and microRNA-142-3p are regulators of myeloid differentiation and acute myeloid leukemia.
Topics: Antineoplastic Agents; Carcinogens; Cell Differentiation; Cell Line, Tumor; Cell Transformation, Neoplastic; Gene Expression Regulation, Leukemic; HEK293 Cells; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; MicroRNAs; Myeloid Cells; Tetradecanoylphorbol Acetate; Transfection; Tretinoin | 2012 |
Phosphoinositol 3-kinase, a novel target molecule for the inhibitory effects of juglone on TPA-induced cell transformation.
Topics: Androstadienes; Animals; Cell Line; Cell Transformation, Neoplastic; Chromones; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Endothelial Growth Factors; Extracellular Signal-Regulated MAP Kinases; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Mice; Morpholines; Naphthoquinones; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-fos; Ribosomal Protein S6 Kinases, 90-kDa; Skin; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Wortmannin | 2012 |
Miz1 is a critical repressor of cdkn1a during skin tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Differentiation; Cell Proliferation; Cell Transformation, Neoplastic; Cyclin-Dependent Kinase Inhibitor p15; Cyclin-Dependent Kinase Inhibitor p21; Mice; Mice, Transgenic; Neoplasms, Experimental; Nuclear Proteins; Protein Inhibitors of Activated STAT; Protein Structure, Tertiary; Skin Neoplasms; Tetradecanoylphorbol Acetate; Ubiquitin-Protein Ligases | 2012 |
TPA-induced cell transformation provokes a complex formation between Pin1 and 90 kDa ribosomal protein S6 kinase 2.
Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Enzyme Activation; Humans; Mice; NIMA-Interacting Peptidylprolyl Isomerase; Peptidylprolyl Isomerase; Phosphorylation; Protein Binding; Protein Interaction Mapping; Protein Processing, Post-Translational; Ribosomal Protein S6 Kinases, 90-kDa; Tetradecanoylphorbol Acetate | 2012 |
Effects of the tropical ginger compound,1'-acetoxychavicol acetate, against tumor promotion in K5.Stat3C transgenic mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alpinia; Animals; Benzyl Alcohols; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Fluocinolone Acetonide; Humans; Mice; Mice, Transgenic; NF-kappa B; Plant Extracts; Skin Neoplasms; STAT3 Transcription Factor; Tetradecanoylphorbol Acetate; Zingiber officinale | 2012 |
A transposon-based analysis of gene mutations related to skin cancer development.
Topics: Animals; Carcinogens; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Carrier Proteins; Cell Transformation, Neoplastic; DNA Mutational Analysis; DNA Transposable Elements; Genes, ras; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Humans; Intracellular Signaling Peptides and Proteins; Keratin-15; Keratin-5; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Transgenic; Mutation; Nuclear Proteins; Promoter Regions, Genetic; Receptor, Notch1; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transposases | 2013 |
Inhibition of CXCR2 profoundly suppresses inflammation-driven and spontaneous tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenoma; Animals; Animals, Inbred Strains; Azoxymethane; Cell Transformation, Neoplastic; Chemokines, CXC; Colitis; Colonic Neoplasms; Dermatitis, Contact; Dextran Sulfate; Gene Expression; Mice; Mice, 129 Strain; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Neutrophils; Papilloma; Peroxidase; Precancerous Conditions; Receptors, Interleukin-8B; Skin Neoplasms; Statistics, Nonparametric; Tetradecanoylphorbol Acetate; Tumor Burden | 2012 |
Tissue-specific opposing functions of the inflammasome adaptor ASC in the regulation of epithelial skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adaptor Proteins, Signal Transducing; Animals; Apoptosis Regulatory Proteins; CARD Signaling Adaptor Proteins; Caspase 1; Cell Proliferation; Cell Transformation, Neoplastic; Cytokines; Cytoskeletal Proteins; Down-Regulation; Epithelium; Humans; Inflammasomes; Inflammation; Keratinocytes; Mice; Mice, Knockout; Myeloid Cells; Neoplasms, Squamous Cell; Organ Specificity; Receptors, Interleukin-1; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Microenvironment; Tumor Suppressor Protein p53 | 2012 |
The p53-p66Shc apoptotic pathway is dispensable for tumor suppression whereas the p66Shc-generated oxidative stress initiates tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogens; Cell Transformation, Neoplastic; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxidative Stress; Shc Signaling Adaptor Proteins; Src Homology 2 Domain-Containing, Transforming Protein 1; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53; Ultraviolet Rays | 2013 |
Withaferin A suppresses tumor promoter 12-O-tetradecanoylphorbol 13-acetate-induced decreases in isocitrate dehydrogenase 1 activity and mitochondrial function in skin epidermal JB6 cells.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Cell Respiration; Cell Transformation, Neoplastic; Down-Regulation; Epidermis; Female; Glycolysis; Isocitrate Dehydrogenase; Ketoglutaric Acids; Lactic Acid; Membrane Potential, Mitochondrial; Mice; Mice, Inbred DBA; Mitochondria; Tetradecanoylphorbol Acetate; Withanolides | 2013 |
Baicalein inhibits DMBA/TPA-induced skin tumorigenesis in mice by modulating proliferation, apoptosis, and inflammation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Apoptosis; Cell Proliferation; Cell Transformation, Neoplastic; Female; Flavanones; Hyperplasia; Inflammation; Mice; Mice, Inbred C57BL; Plant Extracts; Scutellaria baicalensis; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2013 |
Inhibitory effects of Opuntia humifusa on 7, 12-dimethyl- benz[a]anthracene and 12-O-tetradecanoylphorbol-13- acetate induced two-stage skin carcinogenesis.
Topics: Analysis of Variance; Animals; Anticarcinogenic Agents; Apoptosis; Benz(a)Anthracenes; Cell Transformation, Neoplastic; Female; Glutathione Transferase; Lipid Peroxidation; Mice; Mice, Inbred BALB C; Opuntia; Oxidative Stress; Phytotherapy; Plant Preparations; Skin; Skin Neoplasms; Statistics, Nonparametric; Superoxide Dismutase; Tetradecanoylphorbol Acetate | 2012 |
High expression of microRNA‑127 is involved in cell cycle arrest in MC‑3 mucoepidermoid carcinoma cells.
Topics: Animals; Carcinoma, Mucoepidermoid; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Fibroblasts; G1 Phase Cell Cycle Checkpoints; Humans; Mice; MicroRNAs; S Phase Cell Cycle Checkpoints; Salivary Gland Neoplasms; Sp1 Transcription Factor; Tetradecanoylphorbol Acetate; Transfection | 2013 |
PKM2 inhibitor shikonin suppresses TPA-induced mitochondrial malfunction and proliferation of skin epidermal JB6 cells.
Topics: AMP-Activated Protein Kinases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Blotting, Western; Carrier Proteins; Cell Adhesion; Cell Proliferation; Cell Respiration; Cell Transformation, Neoplastic; Cells, Cultured; Epidermis; Humans; Membrane Potential, Mitochondrial; Membrane Proteins; Mice; Mitochondria; Naphthoquinones; Oxygen Consumption; Tetradecanoylphorbol Acetate; Thyroid Hormone-Binding Proteins; Thyroid Hormones | 2014 |
Peracetylated (-)-epigallocatechin-3-gallate (AcEGCG) potently prevents skin carcinogenesis by suppressing the PKD1-dependent signaling pathway in CD34+ skin stem cells and skin tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetates; Animals; Antigens, CD34; Catechin; CCAAT-Enhancer-Binding Proteins; Cell Proliferation; Cell Transformation, Neoplastic; Chemoprevention; Cyclic AMP Response Element-Binding Protein; Cyclooxygenase 2; Extracellular Signal-Regulated MAP Kinases; Male; Mice; Mice, Inbred ICR; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinase 9; Mitotic Index; Nitric Oxide Synthase Type II; Ornithine Decarboxylase; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinase; Phosphorylation; Protein Kinase C; Proto-Oncogene Proteins c-akt; Skin Neoplasms; Stem Cells; Tetradecanoylphorbol Acetate; Vascular Endothelial Growth Factor A | 2013 |
Aberrantly expressed c-Jun and JunB are a hallmark of Hodgkin lymphoma cells, stimulate proliferation and synergize with NF-kappa B.
Topics: Cell Division; Cell Transformation, Neoplastic; Cyclin D2; Cyclins; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; Genes, jun; Hodgkin Disease; Humans; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; MAP Kinase Signaling System; Mitogens; Neoplasm Proteins; NF-kappa B; Proto-Oncogene Mas; Proto-Oncogene Proteins c-jun; Proto-Oncogene Proteins c-met; Receptors, CCR7; Receptors, Chemokine; Recombinant Fusion Proteins; Reed-Sternberg Cells; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription, Genetic; Transfection; Tumor Cells, Cultured; Ultraviolet Rays | 2002 |
Cdk4 deficiency inhibits skin tumor development but does not affect normal keratinocyte proliferation.
Topics: Animals; Carcinogens; Cell Division; Cell Transformation, Neoplastic; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinases; Keratinocytes; Mice; Mice, Inbred C57BL; Mice, Knockout; Proto-Oncogene Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2002 |
PKC, p42/44 MAPK and p38 MAPK regulate hepatocyte growth factor secretion from human astrocytoma cells.
Topics: Astrocytoma; Cell Division; Cell Transformation, Neoplastic; Enzyme Inhibitors; Hepatocyte Growth Factor; Humans; MAP Kinase Kinase 1; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Neoplasm Invasiveness; p38 Mitogen-Activated Protein Kinases; Protein Kinase C; Protein Serine-Threonine Kinases; Protein Synthesis Inhibitors; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2002 |
Flavanones structure-related inhibition on TPA-induced tumor promotion through suppression of extracellular signal-regulated protein kinases: involvement of prostaglandin E2 in anti-promotive process.
Topics: 3T3 Cells; Animals; Biphenyl Compounds; Carcinogens; Cell Division; Cell Transformation, Neoplastic; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Fibroblasts; Flavonoids; Free Radical Scavengers; Gene Expression Regulation; Isoenzymes; JNK Mitogen-Activated Protein Kinases; Mice; Mitogen-Activated Protein Kinases; Ornithine Decarboxylase; Phosphorylation; Picrates; Prostaglandin-Endoperoxide Synthases; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Thymidine | 2002 |
Cell transformation by v-Jun deactivates ERK MAP kinase signalling.
Topics: Animals; Blotting, Western; Cell Division; Cell Transformation, Neoplastic; Chick Embryo; Down-Regulation; Fibroblasts; Humans; Immunoenzyme Techniques; MAP Kinase Kinase Kinase 1; Mitogen-Activated Protein Kinases; Oncogene Protein p65(gag-jun); Phosphorylation; Protein Serine-Threonine Kinases; Retroviridae; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2002 |
Identification of Dss1 as a 12-O-tetradecanoylphorbol-13-acetate-responsive gene expressed in keratinocyte progenitor cells, with possible involvement in early skin tumorigenesis.
Topics: Animals; Base Sequence; Cell Cycle Proteins; Cell Division; Cell Transformation, Neoplastic; DNA Primers; Gene Expression Profiling; Gene Expression Regulation; In Situ Hybridization; Keratinocytes; Male; Mice; Proteins; Reverse Transcriptase Polymerase Chain Reaction; Skin Neoplasms; Subcellular Fractions; Tetradecanoylphorbol Acetate | 2003 |
NS-398 and piroxicam suppress UVB-induced activator protein 1 activity by mechanisms independent of cyclooxygenase-2.
Topics: Animals; Blotting, Western; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; DNA; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Isoenzymes; JNK Mitogen-Activated Protein Kinases; Luciferases; MAP Kinase Kinase 4; Membrane Proteins; Mice; Mitogen-Activated Protein Kinase Kinases; Nitrobenzenes; Phosphorylation; Piroxicam; Prostaglandin-Endoperoxide Synthases; Sulfonamides; Tetradecanoylphorbol Acetate; Time Factors; Transcription Factor AP-1; Transcription Factors; Ultraviolet Rays | 2003 |
Matrix metalloproteinase-19 is expressed by proliferating epithelium but disappears with neoplastic dedifferentiation.
Topics: Blotting, Northern; Blotting, Western; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cell Differentiation; Cell Division; Cell Transformation, Neoplastic; Down-Regulation; Female; Fibroblasts; Humans; Immunoenzyme Techniques; Keratinocytes; Male; Matrix Metalloproteinases, Secreted; Metalloendopeptidases; Middle Aged; RNA, Messenger; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2003 |
Rhein inhibits TPA-induced activator protein-1 activation and cell transformation by blocking the JNK-dependent pathway.
Topics: Animals; Anthraquinones; Blotting, Western; Cell Line; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Enzyme Inhibitors; JNK Mitogen-Activated Protein Kinases; Luciferases; MAP Kinase Kinase 4; Mice; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Models, Chemical; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Tetradecanoylphorbol Acetate; Time Factors; Transcription Factor AP-1; Transcription, Genetic; Transcriptional Activation | 2003 |
Partial oncogenic transformation of chicken embryo fibroblasts by Jun dimerization protein 2, a negative regulator of TRE- and CRE-dependent transcription.
Topics: Activating Transcription Factor 2; Animals; Cell Transformation, Neoplastic; Chick Embryo; Cyclic AMP Response Element-Binding Protein; Fibroblasts; Gene Expression Regulation, Neoplastic; Repressor Proteins; Response Elements; Tetradecanoylphorbol Acetate; Transcription Factors; Transfection | 2003 |
IL-1 alpha, innate immunity, and skin carcinogenesis: the effect of constitutive expression of IL-1 alpha in epidermis on chemical carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; DNA-Binding Proteins; Epidermis; Female; Humans; Immunity, Innate; Interleukin-1; Keratin-14; Keratins; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Nuclear Proteins; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transgenes | 2003 |
Enhancement of carcinogen-induced malignant cell transformation by prostaglandin F(2 alpha).
Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Drug Synergism; Fibroblasts; Methylcholanthrene; Methylnitronitrosoguanidine; Mice; Mice, Inbred C3H; Nitrobenzenes; Polychlorinated Dibenzodioxins; Sulfonamides; Tetradecanoylphorbol Acetate | 2003 |
Osteopontin induction is required for tumor promoter-induced transformation of preneoplastic mouse cells.
Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Dexamethasone; Fibronectins; Mice; Osteopontin; Precancerous Conditions; Serum Albumin, Bovine; Sialoglycoproteins; Tetradecanoylphorbol Acetate | 2003 |
Anthocyanidins inhibit activator protein 1 activity and cell transformation: structure-activity relationship and molecular mechanisms.
Topics: Animals; Anthocyanins; Anthracenes; Anticarcinogenic Agents; Butadienes; Cell Transformation, Neoplastic; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinases; Nitriles; Phosphorylation; Structure-Activity Relationship; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Transcription Factor AP-1 | 2004 |
Novel mechanisms of sublethal oxidant toxicity: induction of premature senescence in human fibroblasts confers tumor promoter activity.
Topics: Carcinogens; Cell Adhesion; Cell Communication; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cellular Senescence; Coculture Techniques; Connexin 43; Culture Media, Conditioned; Extracellular Matrix; Fibroblasts; Gap Junctions; Humans; Keratinocytes; Models, Biological; Neoplasms; Oxidants; Oxidative Stress; Tetradecanoylphorbol Acetate; Tumor Stem Cell Assay | 2003 |
RING protein Trim32 associated with skin carcinogenesis has anti-apoptotic and E3-ubiquitin ligase properties.
Topics: Animals; Apoptosis; Carcinoma, Squamous Cell; Cell Division; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; Genes, p53; Head and Neck Neoplasms; Humans; Keratinocytes; Mice; Mice, Nude; RNA, Messenger; Skin Neoplasms; Skin Transplantation; Tetradecanoylphorbol Acetate; Transcription Factors; Transduction, Genetic; Tripartite Motif Proteins; Tumor Necrosis Factor-alpha; Ubiquitin-Protein Ligases; Ultraviolet Rays | 2004 |
12-O-tetradecanoylphorbol-13-acetate and UV radiation-induced nucleoside diphosphate protein kinase B mediates neoplastic transformation of epidermal cells.
Topics: Animals; Antigens, CD34; Arginine; Aspartic Acid; Cell Transformation, Neoplastic; Cells, Cultured; Cloning, Molecular; Culture Media, Serum-Free; DNA, Complementary; Epidermal Cells; Epidermis; Female; Gene Dosage; Glycine; Homozygote; Humans; Immunoblotting; In Situ Hybridization; Keratinocytes; Kinetics; Mice; Mutagenesis, Site-Directed; Mutation; Nucleoside-Diphosphate Kinase; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Reverse Transcriptase Polymerase Chain Reaction; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Tissue Distribution; Transfection; Ultraviolet Rays; Up-Regulation | 2004 |
The c-Jun dimerization protein 2 inhibits cell transformation and acts as a tumor suppressor gene.
Topics: Animals; Blotting, Western; Cell Cycle Proteins; Cell Differentiation; Cell Division; Cell Line, Tumor; Cell Separation; Cell Transformation, Neoplastic; Chick Embryo; Cyclic AMP; Cyclin D; Cyclin-Dependent Kinase Inhibitor p27; Cyclins; DNA; Fibroblasts; Flow Cytometry; Genes, Tumor Suppressor; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Mice; Mice, SCID; Muscle, Skeletal; NIH 3T3 Cells; Osteoclasts; Protein Structure, Tertiary; Repressor Proteins; Tetradecanoylphorbol Acetate; Time Factors; Transcription Factor AP-1; Transcription, Genetic; Transfection; Tumor Suppressor Proteins | 2004 |
Inhibition of AP-1 and neoplastic transformation by fresh apple peel extract.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Division; Cell Line; Cell Transformation, Neoplastic; Electron Spin Resonance Spectroscopy; Genes, Reporter; Hydrogen Peroxide; Hydroxyl Radical; Luciferases; Malus; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neoplasms, Experimental; Phosphorylation; Plant Extracts; Reactive Oxygen Species; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate; Time Factors; Transcription Factor AP-1; Transcriptional Activation; Transgenes; Ultraviolet Rays | 2004 |
Adhesion, migration, transcriptional, interferon-inducible, and other signaling molecules newly implicated in cancer susceptibility and resistance of JB6 cells by cDNA microarray analyses.
Topics: Animals; Antineoplastic Agents; Biomarkers, Tumor; Carcinogens; Cell Adhesion; Cell Movement; Cell Transformation, Neoplastic; Drug Resistance, Neoplasm; Gene Expression Profiling; Genetic Predisposition to Disease; Interferons; Mice; Neoplasm Proteins; Oligonucleotide Array Sequence Analysis; RNA, Messenger; RNA, Neoplasm; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription, Genetic | 2004 |
Lipopolysaccharide enhancement of 12-o-tetradecanoylphorbol 13-acetate-mediated transformation in rat glioma C6, accompanied by induction of inducible nitric oxide synthase.
Topics: Animals; Carcinogens; Cell Line, Tumor; Cell Survival; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Induction; Enzyme Inhibitors; Flavanones; Gene Expression; Glioma; Lipopolysaccharides; Matrix Metalloproteinase 9; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Quercetin; Rats; Tetradecanoylphorbol Acetate | 2004 |
Nitric oxide does not mediate but inhibits transformation and tumor phenotype.
Topics: Animals; Apoptosis; Base Sequence; Cell Line; Cell Transformation, Neoplastic; DNA Primers; Mice; NF-kappa B; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Phenotype; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Transcriptional Activation; Tumor Necrosis Factor-alpha | 2003 |
V599EB-RAF is an oncogene in melanocytes.
Topics: Animals; Carcinogens; Cell Line, Tumor; Cell Transformation, Neoplastic; Female; Humans; MAP Kinase Signaling System; Melanocytes; Melanoma; Mice; Mice, Nude; Oncogenes; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-raf; Tetradecanoylphorbol Acetate; Transfection | 2004 |
Dominant-negative c-Jun (TAM67) target genes: HMGA1 is required for tumor promoter-induced transformation.
Topics: Animals; Butadienes; Cell Line; Cell Transformation, Neoplastic; Clone Cells; Cyclin D1; Disease Susceptibility; DNA, Complementary; Epidermal Cells; Epidermis; Gene Expression Profiling; Genes, jun; HMGA1a Protein; HMGA1b Protein; MAP Kinase Kinase Kinase 1; MAP Kinase Kinase Kinases; MAP Kinase Signaling System; Mice; Mice, Transgenic; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Nitriles; Oligonucleotide Array Sequence Analysis; Oligonucleotides, Antisense; Osteopontin; Proto-Oncogene Proteins c-jun; Sialoglycoproteins; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription, Genetic | 2004 |
Novel p21-activated kinase-dependent protrusions characteristically formed at the edge of transformed cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Actins; Animals; Calcium-Binding Proteins; Carcinogens; cdc42 GTP-Binding Protein; Cell Cycle Proteins; Cell Line, Transformed; Cell Line, Tumor; Cell Size; Cell Surface Extensions; Cell Transformation, Neoplastic; Enzyme Activation; Epithelial Cells; Guanine Nucleotide Exchange Factors; Lysophospholipids; Microscopy, Electron, Scanning; Models, Biological; p21-Activated Kinases; Protein Serine-Threonine Kinases; Rats; Rats, Inbred F344; Rho Guanine Nucleotide Exchange Factors; Tetradecanoylphorbol Acetate; Time Factors; Trachea | 2004 |
A novel role for mixed-lineage kinase-like mitogen-activated protein triple kinase alpha in neoplastic cell transformation and tumor development.
Topics: Animals; Base Sequence; Carcinogens; Cell Adhesion; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Epidermal Growth Factor; MAP Kinase Kinase Kinases; MAP Kinase Signaling System; Mice; Mice, Nude; Molecular Sequence Data; Phosphorylation; RNA, Small Interfering; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factors | 2004 |
Early detection of alterations associated to oral cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Analysis of Variance; Animals; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cheek; Cricetinae; Hyperplasia; Mesocricetus; Mouth Neoplasms; Neoplasms, Radiation-Induced; Nucleolus Organizer Region; Silver Staining; Statistics, Nonparametric; Tetradecanoylphorbol Acetate | 2000 |
Alpha 2-HS glycoprotein (fetuin-A) modulates murine skin tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; alpha-2-HS-Glycoprotein; Animals; Apoptosis; Blood Proteins; Cell Proliferation; Cell Transformation, Neoplastic; Mice; Mice, Inbred C57BL; Mutation; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2004 |
Melittin shares certain cellular effects with phorbol ester tumour promoters.
Topics: Animals; Arachidonic Acid; Bee Venoms; Bees; Cell Differentiation; Cell Division; Cell Line; Cell Line, Tumor; Cell Transformation, Neoplastic; Melanoma; Melitten; Mice; Prostaglandins; Tetradecanoylphorbol Acetate | 1979 |
[Induction of human oral carcinoma by human papillomavirus 16 E6/E7 and TPA].
Topics: Animals; Carcinogens; Carcinoma; Cell Transformation, Neoplastic; Cells, Cultured; Human papillomavirus 16; Humans; Mice; Mice, SCID; Mouth Neoplasms; Oncogene Proteins, Viral; Papillomavirus E7 Proteins; Papillomavirus Infections; Repressor Proteins; Tetradecanoylphorbol Acetate | 2003 |
Delayed and sustained activation of extracellular signal-regulated kinase in human keratinocytes by UVA: implications in carcinogenesis.
Topics: Animals; Apoptosis; Blotting, Western; Calcium; Carbazoles; Caspase 3; Caspases; Cell Line; Cell Line, Tumor; Cell Membrane; Cell Survival; Cell Transformation, Neoplastic; Chelating Agents; COS Cells; Cytosol; Dose-Response Relationship, Radiation; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; ErbB Receptors; Estrenes; Flow Cytometry; Genes, Dominant; Golgi Apparatus; Humans; Indoles; Keratinocytes; Mitogen-Activated Protein Kinase 3; Models, Biological; Neoplasms; Plasmids; Protein Kinase C; Pyrrolidinones; ras Proteins; Skin Neoplasms; Subcellular Fractions; Tetradecanoylphorbol Acetate; Time Factors; Transfection; Ultraviolet Rays | 2004 |
Potential chemopreventive properties of extract from baked sweet potato (Ipomoea batatas Lam. Cv. Koganesengan).
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Cell Line; Cell Transformation, Neoplastic; Chemoprevention; HL-60 Cells; Hot Temperature; Humans; Ipomoea batatas; Mice; Plant Extracts; Plant Tubers; Tetradecanoylphorbol Acetate | 2004 |
An antitumorigenic role for murine 8S-lipoxygenase in skin carcinogenesis.
Topics: Animals; Arachidonate Lipoxygenases; Carcinoma; Cell Line; Cell Proliferation; Cell Transformation, Neoplastic; Female; Gene Expression; Genes, Tumor Suppressor; Hydroxyeicosatetraenoic Acids; Linoleic Acids, Conjugated; Membrane Proteins; Mice; Mice, Transgenic; Papilloma; Promoter Regions, Genetic; RNA, Messenger; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transgenes | 2005 |
Blackberry extracts inhibit activating protein 1 activation and cell transformation by perturbing the mitogenic signaling pathway.
Topics: Antioxidants; Cell Division; Cell Line, Tumor; Cell Transformation, Neoplastic; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Fruit; Humans; Mitogen-Activated Protein Kinase Kinases; Plant Extracts; Reactive Oxygen Species; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factor AP-1 | 2004 |
Crucial role of phospholipase Cepsilon in chemical carcinogen-induced skin tumor development.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Proliferation; Cell Transformation, Neoplastic; Mice; Mice, Inbred C57BL; Mutation; Phosphoinositide Phospholipase C; ras Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Type C Phospholipases | 2004 |
The telomerase RNA component Terc is required for the tumour-promoting effects of Tert overexpression.
Topics: Animals; Cell Transformation, Neoplastic; Chromosomal Instability; Chromosome Aberrations; DNA-Binding Proteins; Gene Deletion; In Situ Hybridization, Fluorescence; Keratinocytes; Mice; Mice, Knockout; Mutation; Neoplasms; Protein Subunits; RNA; Skin Neoplasms; Telomerase; Tetradecanoylphorbol Acetate; Wound Healing | 2005 |
NUP98-HOXD13 transgenic mice develop a highly penetrant, severe myelodysplastic syndrome that progresses to acute leukemia.
Topics: Acute Disease; Animals; Carcinogens; Cell Differentiation; Cell Transformation, Neoplastic; Disease Models, Animal; Homeodomain Proteins; Humans; K562 Cells; Leukemia; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myelodysplastic Syndromes; Myeloid Ecotropic Viral Integration Site 1 Protein; Neoplasm Proteins; Nuclear Pore Complex Proteins; Penetrance; Phenotype; Severity of Illness Index; Tetradecanoylphorbol Acetate; Transcription Factors; Translocation, Genetic | 2005 |
[Gene expression profiles in early stage of BALB/c 3T3 cells' transformation promoted with 12-O-tetradecanoylphorbol-13-acetate].
Topics: Animals; Apoptosis; BALB 3T3 Cells; Cell Cycle; Cell Differentiation; Cell Proliferation; Cell Transformation, Neoplastic; Flow Cytometry; Gene Expression; Gene Expression Profiling; Methylnitronitrosoguanidine; Mice; Oligonucleotide Array Sequence Analysis; Tetradecanoylphorbol Acetate | 2005 |
The effect of PPARgamma ligands on UV- or chemically-induced carcinogenesis in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Proliferation; Cell Transformation, Neoplastic; Chromans; Diet; Female; Keratinocytes; Ligands; Mice; PPAR gamma; RNA, Messenger; Rosiglitazone; Skin Neoplasms; Tetradecanoylphorbol Acetate; Thiazolidinediones; Troglitazone; Ultraviolet Rays | 2005 |
Inhibition of activator protein-1, NF-kappaB, and MAPKs and induction of phase 2 detoxifying enzyme activity by chlorogenic acid.
Topics: Agar; Animals; Antineoplastic Agents; Antioxidants; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Chlorogenic Acid; Cytosol; DNA-Binding Proteins; Dose-Response Relationship, Drug; Electric Impedance; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Genes, Reporter; Glutathione Transferase; Humans; Immunohistochemistry; Isoenzymes; Luciferases; MAP Kinase Signaling System; Mice; NADH, NADPH Oxidoreductases; NF-E2-Related Factor 2; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Plasmids; Protein Transport; Tetradecanoylphorbol Acetate; Trans-Activators; Transcription Factor AP-1; Transcriptional Activation; Ultraviolet Rays | 2005 |
Early growth response 1 acts as a tumor suppressor in vivo and in vitro via regulation of p53.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Growth Processes; Cell Transformation, Neoplastic; Chromosome Mapping; DNA Damage; DNA-Binding Proteins; Early Growth Response Protein 1; Female; Fibroblasts; Gene Expression Profiling; Genes, Tumor Suppressor; Immediate-Early Proteins; Male; Mice; Mice, Inbred C57BL; Promoter Regions, Genetic; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factors; Tumor Suppressor Protein p53; Up-Regulation | 2005 |
c-Fos-dependent induction of the small ras-related GTPase Rab11a in skin carcinogenesis.
Topics: Animals; Blotting, Northern; Blotting, Western; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Electrophoretic Mobility Shift Assay; Female; Fibroblasts; Fluorescent Antibody Technique; Humans; In Situ Hybridization; Keratinocytes; Mice; Mice, Transgenic; Promoter Regions, Genetic; Proto-Oncogene Proteins c-fos; rab GTP-Binding Proteins; Reverse Transcriptase Polymerase Chain Reaction; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2005 |
Chemopreventive effect of bicyclol on malignant transformation of WB-F344 rat liver epithelial cells and its effect on related signal transduction in vitro.
Topics: Animals; Antineoplastic Agents; Benz(a)Anthracenes; Biphenyl Compounds; Cell Communication; Cell Line; Cell Proliferation; Cell Transformation, Neoplastic; Colony-Forming Units Assay; Enzyme Induction; Epithelial Cells; I-kappa B Proteins; Liver Neoplasms; Male; Methylcholanthrene; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NF-KappaB Inhibitor alpha; Protein Kinase C-alpha; Rats; Rats, Inbred F344; Signal Transduction; Tetradecanoylphorbol Acetate | 2006 |
Raised expression of the antiapoptotic protein ped/pea-15 increases susceptibility to chemically induced skin tumor development.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Apoptosis Regulatory Proteins; Blotting, Western; Carcinogens; Caspase 3; Caspases; Cell Transformation, Neoplastic; Cells, Cultured; Cocarcinogenesis; DNA, Antisense; Enzyme Activation; Humans; Intracellular Signaling Peptides and Proteins; Keratinocytes; Male; Mice; Mice, Inbred C57BL; Mice, Nude; Mice, Transgenic; Papilloma; Phosphoproteins; Sarcoma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transfection | 2005 |
Reduced excision repair cross-complementing 1 expression associates with enhanced papilloma formation and fibroblast transformation after genetic disruption of secreted protein acidic and rich in cysteine.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cells, Cultured; DNA Adducts; DNA-Binding Proteins; Embryo, Mammalian; Endonucleases; Female; Fibroblasts; Gene Expression; Genotype; Male; Mice; Mice, Inbred Strains; Mice, Knockout; Osteonectin; Papilloma; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Skin; Tetradecanoylphorbol Acetate; Time Factors | 2005 |
3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone [MX] shows initiating and promoting activities in a two-stage BALB/c 3T3 cell transformation assay.
Topics: Animals; BALB 3T3 Cells; Biological Assay; Carcinogens; Cell Transformation, Neoplastic; Coculture Techniques; Furans; Mice; Tetradecanoylphorbol Acetate; Thioguanine | 2005 |
Global genomic changes induced by two-stage carcinogen exposure are precancerous alterations in non-transformed human liver epithelial THLE-3 cells.
Topics: Benzo(a)pyrene; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 17; DNA; DNA Damage; G1 Phase; Gene Expression Regulation, Neoplastic; Genome, Human; Genotype; Humans; In Situ Hybridization, Fluorescence; Laser Scanning Cytometry; Liver; Methylnitronitrosoguanidine; Neoplasms; Nucleic Acid Hybridization; Phenotype; Ploidies; Resting Phase, Cell Cycle; Tetradecanoylphorbol Acetate; Time Factors | 2005 |
Chemopreventive effect of dimethyl dicarboxylate biphenyl on malignant transformation of WB-F344 rat liver epithelial cells.
Topics: Animals; Antineoplastic Agents; Carcinogens; Cell Communication; Cell Transformation, Neoplastic; Cells, Cultured; Dioxoles; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Epithelial Cells; Gap Junctions; Hepatocytes; Rats; Rats, Inbred F344; Tetradecanoylphorbol Acetate | 2005 |
Lack of expression of the EP2 but not EP3 receptor for prostaglandin E2 results in suppression of skin tumor development.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogens; Cell Growth Processes; Cell Transformation, Neoplastic; Cyclic AMP; Dinoprostone; Drug Eruptions; Female; Hyperplasia; Keratinocytes; Mice; Mice, Knockout; Neovascularization, Pathologic; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP3 Subtype; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2005 |
An inter-laboratory collaborative study by the Non-Genotoxic Carcinogen Study Group in Japan, on a cell transformation assay for tumour promoters using Bhas 42 cells.
Topics: Animal Testing Alternatives; Animals; BALB 3T3 Cells; Carcinogenicity Tests; Carcinogens; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Japan; Lithocholic Acid; Mice; Reproducibility of Results; Tetradecanoylphorbol Acetate; Time Factors | 2005 |
PTEN loss promotes rasHa-mediated papillomatogenesis via dual up-regulation of AKT activity and cell cycle deregulation but malignant conversion proceeds via PTEN-associated pathways.
Topics: Animals; Carcinogens; Cell Differentiation; Cell Transformation, Neoplastic; Keratin-13; Keratins; MAP Kinase Signaling System; Mice; Mice, Transgenic; Mifepristone; Oncogene Protein v-akt; Papilloma; PTEN Phosphohydrolase; ras Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate; Up-Regulation | 2006 |
Mechanisms of increased expression of toll-like receptor-4 in human monocyte/macrophage-derived foam cells.
Topics: Cell Line, Tumor; Cell Transformation, Neoplastic; Foam Cells; Gene Expression Regulation; Humans; Leukemia, Monocytic, Acute; Lipoproteins, LDL; Tetradecanoylphorbol Acetate; Toll-Like Receptor 4 | 2005 |
Deregulated minichromosomal maintenance protein MCM7 contributes to oncogene driven tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biomarkers, Tumor; Carcinogens; Carcinoma, Squamous Cell; Cell Cycle Proteins; Cell Proliferation; Cell Transformation, Neoplastic; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; Genes, ras; Humans; Mice; Mice, Transgenic; Minichromosome Maintenance Complex Component 7; Mutation; Neoplasm Proteins; Neoplasms, Experimental; Nuclear Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2006 |
Association of gene expression with sequential proliferation, differentiation and tumor formation in murine skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biomarkers; Carcinogens; Cell Differentiation; Cell Proliferation; Cell Transformation, Neoplastic; Female; Filaggrin Proteins; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genes, ras; Humans; Mice; Mice, Transgenic; Oligonucleotide Array Sequence Analysis; Papilloma; Reverse Transcriptase Polymerase Chain Reaction; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2006 |
Lipopolysaccharide plus 12-o-tetradecanoylphorbol 13-acetate induction of migration and invasion of glioma cells in vitro and in vivo: Differential inhibitory effects of flavonoids.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Carcinogens; Cell Movement; Cell Transformation, Neoplastic; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Flavanones; Flavonoids; Glioma; Humans; Kaempferols; Lipopolysaccharides; MAP Kinase Signaling System; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Nitric Oxide; Nitric Oxide Synthase; Rats; Tetradecanoylphorbol Acetate | 2006 |
Ras mutation promotes p53 activation and apoptosis of skin keratinocytes.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogens; Cell Transformation, Neoplastic; Enzyme Inhibitors; Genes, ras; Keratinocytes; Mice; Mice, Inbred C57BL; Mitochondria; Mutation; NADPH Oxidases; Onium Compounds; Protein Transport; rac1 GTP-Binding Protein; Reactive Oxygen Species; RNA, Small Interfering; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53 | 2006 |
Identification of novel genes expressed during rhabdomyosarcoma differentiation using cDNA microarrays.
Topics: Adult; Cell Line, Tumor; Cell Transformation, Neoplastic; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Male; Membrane Proteins; Mitochondrial Precursor Protein Import Complex Proteins; Muscle, Skeletal; Oligonucleotide Array Sequence Analysis; Protein Precursors; Reverse Transcriptase Polymerase Chain Reaction; Rhabdomyosarcoma; RNA, Messenger; RNA, Neoplasm; Saccharomyces cerevisiae Proteins; Soft Tissue Neoplasms; Tetradecanoylphorbol Acetate; Thymosin | 2006 |
Inhibition of poly(ADP-ribose) polymerase modulates tumor-related gene expression, including hypoxia-inducible factor-1 activation, during skin carcinogenesis.
Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; Hypoxia-Inducible Factor 1, alpha Subunit; Isoquinolines; Mice; Mice, Inbred C57BL; NF-kappa B; Piperidines; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Reverse Transcriptase Polymerase Chain Reaction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factor AP-1 | 2006 |
Involvement of the paxillin pathway in JB6 Cl41 cell transformation.
Topics: Animals; Base Sequence; Cell Growth Processes; Cell Line; Cell Transformation, Neoplastic; Down-Regulation; Epidermal Growth Factor; MAP Kinase Kinase 4; Mice; Molecular Sequence Data; Paxillin; Phosphorylation; Proto-Oncogene Proteins c-jun; RNA, Small Interfering; Serine; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transfection | 2006 |
Disruption of EphA2 receptor tyrosine kinase leads to increased susceptibility to carcinogenesis in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Growth Processes; Cell Transformation, Neoplastic; Enzyme Activation; Ephrin-A1; Female; Genetic Predisposition to Disease; Keratinocytes; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Receptor, EphA2; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2006 |
Skin epidermis lacking the c-Myc gene is resistant to Ras-driven tumorigenesis but can reacquire sensitivity upon additional loss of the p21Cip1 gene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Cyclin-Dependent Kinase Inhibitor p21; Epidermis; Female; Gene Expression Regulation, Neoplastic; Genes, ras; Male; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Proto-Oncogene Proteins c-myc; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Up-Regulation | 2006 |
Homozygous K5Cre transgenic mice have wavy hair and accelerated malignant progression in a murine model of skin carcinogenesis.
Topics: Alopecia; Animals; Carcinogens; Cell Transformation, Neoplastic; Cocarcinogenesis; Disease Models, Animal; Disease Progression; DNA Damage; Female; Genes, ras; Genotype; Hair; Hair Follicle; Homozygote; Integrases; Keratin-15; Keratin-5; Keratinocytes; Male; Mammary Glands, Animal; Mice; Mice, Transgenic; Papilloma; Recombination, Genetic; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2007 |
Inhibitory effects of asiatic acid on 7,12-dimethylbenz[a]anthracene and 12-O-tetradecanoylphorbol 13-acetate-induced tumor promotion in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogens; Cell Transformation, Neoplastic; Cocarcinogenesis; Cyclooxygenase 2; Dose-Response Relationship, Drug; Enzyme Induction; Female; Mice; Mice, Inbred ICR; Nitric Oxide; Nitric Oxide Synthase Type II; Papilloma; Pentacyclic Triterpenes; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Triterpenes | 2007 |
Pro/antioxidant status and AP-1 transcription factor in murine skin following topical exposure to cumene hydroperoxide.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzene Derivatives; Cell Line; Cell Proliferation; Cell Transformation, Neoplastic; Female; Gene Expression Regulation, Neoplastic; Glutathione; Mice; Mice, Transgenic; Oxidation-Reduction; Oxidative Stress; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factor AP-1 | 2007 |
Malignant transformation of DMBA/TPA-induced papillomas and nevi in the skin of mice selectively lacking retinoid-X-receptor alpha in epidermal keratinocytes.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Transformation, Neoplastic; Epidermis; Gene Expression Regulation, Neoplastic; Keratinocytes; Mice; Mice, Transgenic; Nevus, Pigmented; Papilloma; PPAR gamma; Retinoid X Receptor alpha; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2007 |
Peonidin inhibits phorbol-ester-induced COX-2 expression and transformation in JB6 P+ cells by blocking phosphorylation of ERK-1 and -2.
Topics: Animals; Anthocyanins; Antineoplastic Agents, Phytogenic; Cell Line, Transformed; Cell Transformation, Neoplastic; Cyclooxygenase 2 Inhibitors; Growth Inhibitors; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Protein Kinase Inhibitors; Tetradecanoylphorbol Acetate | 2007 |
Dual role of inactivating Lef1 mutations in epidermis: tumor promotion and specification of tumor type.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma, Sebaceous; Animals; Cell Transformation, Neoplastic; Cocarcinogenesis; Cyclin-Dependent Kinase Inhibitor p21; Epidermis; Female; Genes, ras; Lymphoid Enhancer-Binding Factor 1; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Transgenic; Mutation; Sebaceous Gland Neoplasms; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53 | 2007 |
SAG/ROC2/Rbx2 is a novel activator protein-1 target that promotes c-Jun degradation and inhibits 12-O-tetradecanoylphorbol-13-acetate-induced neoplastic transformation.
Topics: Binding Sites; Carrier Proteins; Cell Transformation, Neoplastic; Cloning, Molecular; Consensus Sequence; Doublecortin Protein; Gene Expression Regulation, Neoplastic; Gene Silencing; HeLa Cells; Humans; Promoter Regions, Genetic; Proto-Oncogene Proteins c-jun; RNA-Binding Proteins; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Ubiquitin-Protein Ligases; Ubiquitins | 2007 |
[Expression of mitochondrial ferritin in K562 leukemic cell during TPA-induced cell differentiation].
Topics: Antigens, CD; Cell Proliferation; Cell Transformation, Neoplastic; Ferritins; Humans; Iron-Regulatory Proteins; K562 Cells; Mitochondria; Receptors, Transferrin; RNA, Messenger; Tetradecanoylphorbol Acetate | 2007 |
Expression profile of skin papillomas with high cancer risk displays a unique genetic signature that clusters with squamous cell carcinomas and predicts risk for malignant conversion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biomarkers, Tumor; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Female; Gene Expression Profiling; Immunity, Cellular; Immunophenotyping; Mice; Mice, Inbred SENCAR; Oligonucleotide Array Sequence Analysis; Papilloma; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; Risk Factors; RNA, Messenger; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2007 |
Redox effector factor-1, combined with reactive oxygen species, plays an important role in the transformation of JB6 cells.
Topics: Animals; Annexin A5; Apoptosis; Base Sequence; Cadmium Chloride; Cell Line; Cell Transformation, Neoplastic; DNA Damage; DNA-(Apurinic or Apyrimidinic Site) Lyase; Hydrogen Peroxide; Mice; Oxidative Stress; Reactive Oxygen Species; RNA, Small Interfering; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Ultraviolet Rays | 2007 |
The effect of cyclooxygenase-2 overexpression on skin carcinogenesis is context dependent.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anthralin; Blotting, Northern; Blotting, Western; Carcinogens; Cell Proliferation; Cell Transformation, Neoplastic; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclooxygenase 2; Dermatologic Agents; Drug Resistance, Neoplasm; Female; Humans; Interleukin-1alpha; Mice; Mice, Transgenic; Ornithine Decarboxylase; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2007 |
Decreased c-kit function inhibits enhanced skin carcinogenesis in c-Ha-ras protooncogene transgenic mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Blotting, Western; Carcinogens; Cell Transformation, Neoplastic; Female; Genes, ras; Humans; Male; Mast Cells; Mice; Mice, Inbred C57BL; Mice, Transgenic; Papilloma; Polymerase Chain Reaction; Promoter Regions, Genetic; Proto-Oncogene Proteins c-kit; Proto-Oncogene Proteins p21(ras); Skin Neoplasms; Tetradecanoylphorbol Acetate; Transgenes | 2007 |
Myricetin is a novel natural inhibitor of neoplastic cell transformation and MEK1.
Topics: Animals; Antineoplastic Agents; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Enzyme Inhibitors; Epidermal Growth Factor; Fireflies; Flavonoids; Genes, Reporter; Luciferases; MAP Kinase Kinase 1; Mice; Recombinant Proteins; Tetradecanoylphorbol Acetate | 2007 |
Expression of the human Cathepsin L inhibitor hurpin in mice: skin alterations and increased carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogens; Cathepsin L; Cathepsins; Cell Transformation, Neoplastic; Cysteine Endopeptidases; Humans; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Transgenic; Microarray Analysis; Serpins; Skin; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 2007 |
The role of glycogen synthase kinase 3beta in the transformation of epidermal cells.
Topics: Animals; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Enzyme Activation; Epidermal Growth Factor; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Male; Mice; Mice, Inbred BALB C; Oncogene Protein v-akt; Phosphatidylinositol 3-Kinases; Protein Kinase C; Signal Transduction; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transfection | 2007 |
Forced expression of a constitutively active form of Stat3 in mouse epidermis enhances malignant progression of skin tumors induced by two-stage carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Cell Line, Tumor; Cell Transformation, Neoplastic; Disease Models, Animal; Disease Progression; Epidermis; Keratinocytes; Mice; Mice, Transgenic; Skin Neoplasms; STAT3 Transcription Factor; Tetradecanoylphorbol Acetate | 2008 |
Ribosomal S6 kinase 2 is a key regulator in tumor promoter induced cell transformation.
Topics: Animals; Base Sequence; Carcinogens; Cell Adhesion; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; Epidermal Growth Factor; G1 Phase; Mice; Molecular Sequence Data; NIH 3T3 Cells; Ribosomal Protein S6 Kinases, 90-kDa; Sequence Homology, Nucleic Acid; Tetradecanoylphorbol Acetate; Transfection | 2007 |
SAG/ROC2 E3 ligase regulates skin carcinogenesis by stage-dependent targeting of c-Jun/AP1 and IkappaB-alpha/NF-kappaB.
Topics: Animals; Cell Proliferation; Cell Transformation, Neoplastic; Enzyme Activation; Epidermis; Humans; I-kappa B Proteins; Mice; Mice, Transgenic; NF-kappa B; NF-KappaB Inhibitor alpha; Proto-Oncogene Proteins c-jun; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Ubiquitin-Protein Ligases | 2007 |
Heat shock factor 1 is a powerful multifaceted modifier of carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; DNA-Binding Proteins; Fibroblasts; Gene Expression Regulation, Neoplastic; Genotype; Glucose; Heat Shock Transcription Factors; Humans; Methylnitronitrosoguanidine; Mice; Mice, Inbred BALB C; Mice, Knockout; Mutation; Phenotype; Protein Biosynthesis; Proto-Oncogene Proteins c-sis; ras Proteins; RNA Interference; RNA, Small Interfering; Signal Transduction; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Transcription Factors; Transduction, Genetic; Tumor Suppressor Protein p53 | 2007 |
Cdk2 deficiency decreases ras/CDK4-dependent malignant progression, but not myc-induced tumorigenesis.
Topics: Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Disease Progression; Enzyme Activation; Female; Male; Mice; Mice, Transgenic; Proto-Oncogene Proteins c-myc; ras Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2007 |
Prevention of skin tumorigenesis and impairment of epidermal cell proliferation by targeted aquaporin-3 gene disruption.
Topics: Adenosine Triphosphate; Animals; Aquaporin 3; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; Epidermis; Glycerol; Humans; Keratinocytes; Mice; Mice, Knockout; Neoplasms, Squamous Cell; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2008 |
Hmga1 null mice are less susceptible to chemically induced skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Transformation, Neoplastic; Genetic Predisposition to Disease; HMGA Proteins; Keratinocytes; Mice; Mice, Knockout; Papilloma; Proto-Oncogene Proteins c-fos; rab GTP-Binding Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2008 |
A JNK1/AP-1-dependent, COX-2 induction is implicated in 12-O-tetradecanoylphorbol-13-acetate-induced cell transformation through regulating cell cycle progression.
Topics: Animals; Cell Cycle; Cell Transformation, Neoplastic; Cyclooxygenase 2; Enzyme Induction; Fibroblasts; Humans; I-kappa B Kinase; Mice; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinase 9; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription Factor RelA | 2008 |
Raf and MEK protein kinases are direct molecular targets for the chemopreventive effect of quercetin, a major flavonol in red wine.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Cell Transformation, Neoplastic; Cells, Cultured; MAP Kinase Kinase 1; Mice; NF-kappa B; Proto-Oncogene Proteins c-raf; Quercetin; Resveratrol; Skin; Skin Neoplasms; Stilbenes; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcriptional Activation; Wine | 2008 |
Translation inhibitor Pdcd4 is targeted for degradation during tumor promotion.
Topics: Animals; Apoptosis Regulatory Proteins; Cell Transformation, Neoplastic; Disease Progression; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Transgenic; Proteasome Endopeptidase Complex; Ribosomal Protein S6 Kinases, 70-kDa; RNA-Binding Proteins; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2008 |
Fucoidan from Laminaria cichorioides inhibits AP-1 transactivation and cell transformation in the mouse epidermal JB6 cells.
Topics: Animals; Cell Adhesion; Cell Line; Cell Transformation, Neoplastic; Epidermal Cells; Epidermal Growth Factor; Laminaria; MAP Kinase Signaling System; Mice; Phosphorylation; Polysaccharides; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcriptional Activation | 2008 |
The influence of diesel exhaust on polycyclic aromatic hydrocarbon-induced DNA damage, gene expression, and tumor initiation in Sencar mice in vivo.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Cell Transformation, Neoplastic; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; DNA Adducts; DNA Damage; Mice; Mice, Inbred SENCAR; Particulate Matter; Polycyclic Aromatic Hydrocarbons; Skin Neoplasms; Tetradecanoylphorbol Acetate; Vehicle Emissions | 2008 |
Mitogen- and stress-activated kinase 1-mediated histone H3 phosphorylation is crucial for cell transformation.
Topics: Animals; Cell Growth Processes; Cell Transformation, Neoplastic; Enzyme Activation; Epidermal Growth Factor; G1 Phase; Histones; Isoquinolines; Mice; Phosphorylation; Protein Kinase Inhibitors; Ribosomal Protein S6 Kinases, 90-kDa; RNA, Small Interfering; Skin; Sulfonamides; Tetradecanoylphorbol Acetate; Transcription Factor AP-1 | 2008 |
Polymeric black tea polyphenols inhibit mouse skin chemical carcinogenesis by decreasing cell proliferation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Cell Nucleus; Cell Proliferation; Cell Transformation, Neoplastic; Cyclin-Dependent Kinase Inhibitor p21; Enzyme Activation; Epidermis; Female; Flavonoids; Inflammation Mediators; MAP Kinase Signaling System; Mice; Ornithine Decarboxylase; Phenols; Polymers; Polyphenols; Precancerous Conditions; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Skin Neoplasms; Tea; Tetradecanoylphorbol Acetate; Transcription Factors; Tumor Suppressor Protein p53 | 2008 |
Stage-specific disruption of Stat3 demonstrates a direct requirement during both the initiation and promotion stages of mouse skin tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Blotting, Western; Carcinogens; Cell Transformation, Neoplastic; Immunohistochemistry; Mice; Mice, Transgenic; Polymerase Chain Reaction; Signal Transduction; Skin Neoplasms; STAT3 Transcription Factor; Tamoxifen; Tetradecanoylphorbol Acetate | 2008 |
Reduced susceptibility to two-stage skin carcinogenesis in mice with low circulating insulin-like growth factor I levels.
Topics: Animals; Benz(a)Anthracenes; Cell Proliferation; Cell Transformation, Neoplastic; Epidermis; Female; Genetic Predisposition to Disease; Insulin-Like Growth Factor I; Mice; Models, Biological; Neoplasms; Protein Kinases; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; TOR Serine-Threonine Kinases | 2008 |
Changes in genomic imprinting and gene expression associated with transformation in a model of human osteosarcoma.
Topics: Bone Neoplasms; Carcinogens; Cell Line; Cell Transformation, Neoplastic; DNA Methylation; Gene Expression Regulation, Neoplastic; Genomic Imprinting; Humans; Methylnitronitrosoguanidine; Oligonucleotide Array Sequence Analysis; Osteoblasts; Osteosarcoma; Tetradecanoylphorbol Acetate | 2008 |
Effect of an anticancer agent, vinblastine, on mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Cell Transformation, Viral; Female; Herpesvirus 4, Human; Hyperplasia; Mice; Skin; Tetradecanoylphorbol Acetate; Vinblastine; Virus Activation | 1984 |
Differentiation of chronic lymphocytic leukemia cells after in vitro treatment with Epstein-Barr virus or phorbol ester. I. Immunologic and morphologic studies.
Topics: Aged; Antibody-Producing Cells; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cytoplasm; Female; Herpesvirus 4, Human; Humans; Immunoglobulins; Leukemia, Lymphoid; Lymphocyte Activation; Male; Middle Aged; Phorbols; Tetradecanoylphorbol Acetate | 1984 |
Promoter-induced cellular responses closely correlated with the enhancement of cell transformation.
Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; ErbB Receptors; Lyngbya Toxins; Methylcholanthrene; Mice; Phorbol Esters; Receptors, Cell Surface; Tetradecanoylphorbol Acetate | 1983 |
The study of tumor promotion in a cell culture model for mouse skin--a tissue that exhibits multistage carcinogenesis in vivo.
Topics: Animals; Carcinogens; Cell Differentiation; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Clone Cells; Cocarcinogenesis; Enzyme Induction; Epidermis; gamma-Glutamyltransferase; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1982 |
Enhancement by TPA of phenotypes associated with transformation in carcinogen-treated human cells: evidence for a selective mechanism.
Topics: Cell Aggregation; Cell Transformation, Neoplastic; Cells, Cultured; Cocarcinogenesis; Culture Media; Female; gamma-Glutamyltransferase; Humans; Methylnitronitrosoguanidine; Phenotype; Phorbols; Tetradecanoylphorbol Acetate; Uterus | 1983 |
Regulation of epidermal transglutaminase activity and terminal differentiation by retinoids and phorbol esters.
Topics: Acyltransferases; Animals; Animals, Newborn; Cell Transformation, Neoplastic; Cells, Cultured; Enzyme Induction; Kinetics; Mice; Mice, Inbred BALB C; Phorbols; Protein Biosynthesis; Retinoids; Skin; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transglutaminases; Tretinoin | 1983 |
Phorbol ester tumor promoter modulation of alloantigen-specific T lymphocyte responses.
Topics: Cell Separation; Cell Transformation, Neoplastic; Cytotoxicity, Immunologic; Epitopes; Flow Cytometry; HLA Antigens; Humans; Interferon Inducers; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Phorbols; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1982 |
Modifiers of free radicals inhibit in vitro the oncogenic actions of x-rays, bleomycin, and the tumor promoter 12-O-tetradecanoylphorbol 13-acetate.
Topics: Animals; Bleomycin; Carcinogens; Catalase; Cell Transformation, Neoplastic; Cricetinae; Embryo, Nonmammalian; Female; Free Radicals; Mesocricetus; Phorbols; Pregnancy; Superoxide Dismutase; Tetradecanoylphorbol Acetate | 1983 |
A subpopulation of cultured human keratinocytes which is resistant to the induction of terminal differentiation-related changes by phorbol, 12-myristate, 13-acetate: evidence for an increase in the resistant population following transformation.
Topics: Animals; Carcinoma, Squamous Cell; Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Child; Cholera Toxin; Epidermal Growth Factor; Female; Fetus; Humans; Hydrocortisone; Keratins; Male; Mice; Phorbols; Pregnancy; Simian virus 40; Skin; Skin Physiological Phenomena; Tetradecanoylphorbol Acetate | 1983 |
Functional maturation of membrane potential changes and superoxide-producing capacity during differentiation of human granulocytes.
Topics: Adult; Calcimycin; Cell Differentiation; Cell Transformation, Neoplastic; Deoxyglucose; Dimethyl Sulfoxide; Gramicidin; Granulocytes; Humans; Leukemia, Myeloid; Membrane Potentials; Phagocytosis; Superoxides; Tetradecanoylphorbol Acetate; Tretinoin | 1984 |
Non-promoting hyperplasiogenic agents do not mimic the effects of phorbol, 12-myristate, 13-acetate on terminal differentiation of normal and transformed human keratinocytes.
Topics: Alkynes; Calcimycin; Carcinoma, Squamous Cell; Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Clone Cells; Humans; Hyperplasia; Keratins; Phorbols; Skin; Tetradecanoylphorbol Acetate | 1984 |
Differential effects of complete and second-stage tumour promoters in normal but not transformed human and mouse keratinocytes.
Topics: Carcinogens; Carcinoma, Squamous Cell; Cell Line; Cell Transformation, Neoplastic; Diterpenes; Drug Resistance; Epidermal Cells; Epidermis; Humans; Keratins; Phorbol Esters; Phorbols; Terpenes; Tetradecanoylphorbol Acetate | 1984 |
Effects of 12-O-tetradecanoylphorbol-13-acetate on fibroblasts from individuals genetically predisposed to cancer.
Topics: Cell Adhesion; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cytoskeleton; Disease Susceptibility; Down Syndrome; Epidermal Growth Factor; Fanconi Anemia; Female; Fibroblasts; Humans; Intestinal Polyps; Male; Neoplasms; Phorbols; Tetradecanoylphorbol Acetate; Trypsin; Xeroderma Pigmentosum | 1982 |
Phorbol ester-induced changes in human leukemic pre-B lines.
Topics: Antigens, Neoplasm; B-Lymphocytes; Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; Humans; Immunoglobulin mu-Chains; Leukemia; Leukemia, Lymphoid; Neprilysin; Phorbols; Stem Cells; Tetradecanoylphorbol Acetate | 1984 |
Tumor promoters: an overview of membrane-associated alterations and intracellular events.
Topics: Animals; Carcinogens; Cell Membrane; Cell Nucleus; Cell Transformation, Neoplastic; Cells, Cultured; DNA Replication; Fibroblasts; Mice; Protein Kinase C; Protein Kinases; Tetradecanoylphorbol Acetate | 1984 |
Changes in epidermal growth factor receptors associated with adenovirus transformation, chemical carcinogen transformation and exposure to a phorbol ester tumor promoter.
Topics: Adenoviruses, Human; Animals; Carcinogens; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Epidermal Growth Factor; Mice; Peptides; Phorbols; Rats; Receptors, Cell Surface; Tetradecanoylphorbol Acetate | 1980 |
Factors which disorganize microtubules or microfilaments increase the frequency of cell transformation by polyoma virus.
Topics: Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Colchicine; Cytochalasin B; Epidermal Growth Factor; Griseofulvin; Melitten; Mutagens; Podophyllotoxin; Polyomavirus; Tetradecanoylphorbol Acetate; Vinblastine | 1980 |
The modulating effect of retinoids and a tumor promoter on malignant transformation, sister chromatid exchanges, and Na/K ATPase.
Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Crossing Over, Genetic; Mice; Mice, Inbred C3H; Phorbols; Sister Chromatid Exchange; Sodium-Potassium-Exchanging ATPase; Tetradecanoylphorbol Acetate; Vitamin A | 1981 |
Specific binding of transforming growth factor correlates with promotion of anchorage independence in EGF receptorless mouse JB6 cells.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Clone Cells; Epidermal Growth Factor; ErbB Receptors; Humans; Mice; Peptides; Receptors, Cell Surface; Skin; Tetradecanoylphorbol Acetate; Transforming Growth Factors | 1981 |
Synergistic effects of cigarette smoke extracts, benz (a) pyrene and nickel sulphate on morphological transformation of hamster embryo cells.
Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Cell Transformation, Neoplastic; Cells, Cultured; Cocarcinogenesis; Cricetinae; Embryo, Mammalian; Mesocricetus; Nickel; Smoking; Tetradecanoylphorbol Acetate | 1980 |
Modulation of human T-cell differentiation markers by 12-O-tetradecanoylphorbol-13-acetate.
Topics: 5'-Nucleotidase; Adenosine Deaminase; Adult; Animals; Cell Transformation, Neoplastic; Colony-Forming Units Assay; Cytarabine; DNA; DNA Nucleotidylexotransferase; Histocompatibility Antigens Class II; Humans; Leukemia, Experimental; Nucleotidases; Phorbols; Phytohemagglutinins; Rosette Formation; Sheep; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1981 |
Equivalency of endothelial cell growth supplement to irradiated feeder cells in carcinogen-induced morphologic transformation of Syrian hamster embryo cells.
Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Cell Line; Cell Transformation, Neoplastic; Cocarcinogenesis; Cricetinae; Cytological Techniques; Embryo, Mammalian; Growth Substances; Lymphotoxin-alpha; Mesocricetus; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 1982 |
Dexamethasone synergistically induces chemotactic peptide receptor expression in HL-60 cells.
Topics: Cell Line; Cell Transformation, Neoplastic; Dexamethasone; Dimethyl Sulfoxide; Dimethylformamide; Dose-Response Relationship, Drug; Drug Synergism; Humans; Indomethacin; Methionine; Methyltestosterone; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Oligopeptides; Progesterone; Receptors, Cell Surface; Receptors, Formyl Peptide; Receptors, Steroid; Tetradecanoylphorbol Acetate; Tretinoin | 1982 |
Reversal of the promotional effect of 12-O-tetradecanoylphorbol-13-acetate on morphological transformation of hamster embryo cells by glucocorticoids.
Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Cell Line; Cell Transformation, Neoplastic; Cocarcinogenesis; Corticosterone; Cricetinae; Dexamethasone; Embryo, Mammalian; Glucocorticoids; Hydrocortisone; Mesocricetus; Phorbols; Tetradecanoylphorbol Acetate | 1982 |
Fibrinolytic activity and morphological transformation of hamster embryo cells.
Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Embryo, Mammalian; Fibrinolysis; Mesocricetus; Plasminogen Activators; Protease Inhibitors; Tetradecanoylphorbol Acetate | 1982 |
Epstein-Barr virus induced proteins V: comparison of EBV-specific polypeptides from different virus strains.
Topics: Animals; Antigens, Viral; Burkitt Lymphoma; Capsid Proteins; Cell Transformation, Neoplastic; Chlorocebus aethiops; Glycoproteins; Herpesvirus 4, Human; Humans; Molecular Weight; Peptide Biosynthesis; Peptides; Tetradecanoylphorbol Acetate | 1982 |
Promotional effect of different phorbol esters on morphological transformation of hamster embryo cells.
Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Clone Cells; Cricetinae; Embryo, Mammalian; Mesocricetus; Phorbol Esters; Phorbols; Tetradecanoylphorbol Acetate | 1982 |
Role of plasma fibronectin in the morphological transformation of hamster embryo cells.
Topics: Animals; Benzo(a)pyrene; Benzoates; Benzopyrenes; Cell Movement; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Embryo, Mammalian; Fibronectins; Mesocricetus; Tetradecanoylphorbol Acetate | 1982 |
The presence of p53 transformation-related protein in Ab-MuLV transformed cells is required for their development into lethal tumors in mice.
Topics: Abelson murine leukemia virus; Animals; Cell Line; Cell Transformation, Neoplastic; Cocarcinogenesis; Female; Leukemia Virus, Murine; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Phorbols; Phosphoproteins; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53 | 1983 |
Nutritional and hormonal factors in the prevention of carcinogen-induced neoplastic development in vitro.
Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Mice; Sister Chromatid Exchange; Sodium-Potassium-Exchanging ATPase; Tetradecanoylphorbol Acetate; Thyroid Hormones; Vitamin A | 1981 |
Teleocidin is not mitogenic for 12-O-tetradecanoylphorbol-13-acetate non-proliferative variants of 3T3 cells.
Topics: Alkaloids; Animals; Carcinogens; Cell Division; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; Epidermal Growth Factor; ErbB Receptors; Genetic Variation; Lyngbya Toxins; Mice; Phorbols; Receptors, Cell Surface; Tetradecanoylphorbol Acetate | 1983 |
Expression of transformed morphology and anchorage independent growth of hamster embryo cells.
Topics: Agar; Animals; Benzo(a)pyrene; Benzopyrenes; Cell Adhesion; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cricetinae; Culture Media; Embryo, Mammalian; Neoplasms, Experimental; Teratoma; Tetradecanoylphorbol Acetate | 1983 |
Alteration of phenotype of 'regressor' avian sarcoma cells following treatment with phorbol ester.
Topics: Animals; Avian Sarcoma Viruses; Cell Transformation, Neoplastic; Chick Embryo; Chickens; Female; Fibroblasts; Fluorescent Antibody Technique; Male; Phenotype; Phorbols; Sarcoma, Avian; Tetradecanoylphorbol Acetate | 1983 |
1 alpha,25-Dihydroxyvitamin D3 markedly enhances chemically-induced transformation in BALB 3T3 cells.
Topics: Animals; Calcitriol; Cell Transformation, Neoplastic; Cells, Cultured; Cytosol; Dose-Response Relationship, Drug; Methylcholanthrene; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Protein Binding; Receptors, Calcitriol; Receptors, Steroid; Tetradecanoylphorbol Acetate | 1983 |
Calcium ionophore A-23187 and 12-O-tetradecanoyl-phorbol-13-acetate stimulation of prostaglandin synthesis in herpes simplex virus type 2-transformed rat cells.
Topics: Animals; Calcimycin; Cell Division; Cell Transformation, Neoplastic; Clone Cells; Dinoprost; Dinoprostone; Embryo, Mammalian; Fibrosarcoma; Kinetics; Neoplasm Metastasis; Phorbols; Prostaglandins; Prostaglandins E; Prostaglandins F; Rats; Simplexvirus; Tetradecanoylphorbol Acetate | 1984 |
Gamma-interferon induces expression of the HLA-D antigens on normal and leukemic human myeloid cells.
Topics: B-Lymphocytes; Calcitriol; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Deltaretrovirus; Genes, MHC Class II; Histocompatibility Antigens Class II; Humans; Interferon Type I; Leukemia, Myeloid, Acute; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1984 |
Effects of nickel sulfate on growth and differentiation of normal human bronchial epithelial cells.
Topics: Bronchi; Cell Division; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Epidermal Growth Factor; Epithelium; Humans; In Vitro Techniques; Nickel; Tetradecanoylphorbol Acetate | 1984 |
Accessory function and interleukin 1 production by human leukemic cell lines.
Topics: Cell Line; Cell Transformation, Neoplastic; Histocompatibility Antigens Class II; HLA-DR Antigens; Humans; Interleukin-1; Isoelectric Focusing; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lymphocyte Activation; Lymphocyte Cooperation; Lymphoma, Large B-Cell, Diffuse; Monocytes; Phenotype; Phytohemagglutinins; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1984 |
Carcinogen-induced phenotypic alterations in mammary epithelial cells accompanying the development of neoplastic transformation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Epithelium; Female; Mammary Glands, Animal; Phenotype; Rats; Rats, Inbred Strains; Tamoxifen; Tetradecanoylphorbol Acetate | 1983 |
On the persistence of tumor initiation in two-stage carcinogenesis on mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Age Factors; Animals; Cell Transformation, Neoplastic; Male; Mice; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1983 |
Glycosyltransferase alterations are cell type related when human promyelocytic leukemia (HL-60) cells are treated with various inducers of differentiation.
Topics: Cell Line; Cell Transformation, Neoplastic; Decarboxylation; Deoxyglucose; Dimethyl Sulfoxide; Fucosyltransferases; Galactosyltransferases; Hexosyltransferases; Humans; Leukemia, Myeloid, Acute; Sialyltransferases; Substrate Specificity; Tetradecanoylphorbol Acetate; Tretinoin | 1983 |
Acute effects of 12-O-tetradecanoylphorbol-13-acetate, teleocidin B, or 2,3,7,8-tetrachlorodibenzo-p-dioxin on cultured normal human bronchial epithelial cells.
Topics: Alkaloids; Bronchi; Carcinogens; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Dioxins; DNA Replication; Epithelium; Humans; Kinetics; Lyngbya Toxins; Phorbols; Polychlorinated Dibenzodioxins; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1984 |
Active oxygen acts as a promoter of transformation in mouse embryo C3H/10T1/2/C18 fibroblasts.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Benzopyrenes; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Fibroblasts; Gamma Rays; Mice; Mice, Inbred C3H; Oxygen; Tetradecanoylphorbol Acetate; Xanthine; Xanthine Oxidase; Xanthines | 1984 |
The role of protein phosphorylation at tyrosine in transformation and mitogenesis.
Topics: Alpharetrovirus; Animals; Cell Transformation, Neoplastic; Cell Transformation, Viral; Diglycerides; Fluorescent Antibody Technique; Molecular Weight; Oncogene Protein pp60(v-src); Phosphoproteins; Phosphorylation; Protein Kinases; Protein-Tyrosine Kinases; Retroviridae; Tetradecanoylphorbol Acetate; Viral Proteins | 1984 |
Characterization of a transformation-sensitive protein in the extracellular matrix of chicken embryo fibroblasts.
Topics: Animals; Cell Transformation, Neoplastic; Chick Embryo; Culture Media; Egtazic Acid; Extracellular Matrix; Fibroblasts; Lactoperoxidase; Molecular Weight; Proteins; Tetradecanoylphorbol Acetate | 1984 |
Suppression of the first stage of phorbol 12-tetradecanoate 13-acetate-effected tumor promotion in mouse skin by nontoxic inhibition of DNA synthesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; DNA Replication; Female; Hydroxyurea; Mice; Mice, Inbred Strains; Phorbol Esters; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1984 |
Oncogene-induced transformation of C3H 10T1/2 cells is enhanced by tumor promoters.
Topics: Animals; Carcinogens; Cell Line; Cell Transformation, Neoplastic; DNA, Neoplasm; Humans; Lyngbya Toxins; Mice; Mice, Inbred C3H; Oncogenes; Tetradecanoylphorbol Acetate; Transfection | 1984 |
The proliferative response of low-density human cell cultures to tumor promoters and its relevance to carcinogenic mechanisms in vitro.
Topics: Caenorhabditis elegans Proteins; Carcinogens; Carrier Proteins; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Diterpenes; Fibroblasts; Humans; Lyngbya Toxins; Protein Kinase C; Receptors, Drug; Receptors, Immunologic; Terpenes; Tetradecanoylphorbol Acetate | 1984 |
Studies on the action of tumour promoters and antipromoters on respiratory-tract epithelium.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Epithelial Cells; Epithelium; Humans; Methylnitronitrosoguanidine; Mice; Rats; Respiratory Tract Neoplasms; Tetradecanoylphorbol Acetate; Trachea; Tracheal Neoplasms | 1984 |
Stages of tumour promotion in skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Aging; Animals; Animals, Newborn; Carcinogens; Cell Division; Cell Transformation, Neoplastic; Hyperplasia; Mice; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Wounds and Injuries | 1984 |
Enhancement of primate retrovirus synthesis by tumour promoters.
Topics: Carcinogens; Cell Line; Cell Transformation, Neoplastic; DNA Replication; Female; Humans; Kidney; Leukemia, Lymphoid; Lyngbya Toxins; Ovarian Neoplasms; Phorbols; Retroviridae; Rhabdomyosarcoma; Species Specificity; Tetradecanoylphorbol Acetate; Virus Replication | 1984 |
Modulation of chronic lymphocytic leukemia cells by phorbol ester: increase in Ia expression, IgM secretion and MLR stimulatory capacity.
Topics: Aged; Animals; Binding Sites, Antibody; Cell Transformation, Neoplastic; Dose-Response Relationship, Immunologic; Female; Histocompatibility Antigens Class II; Humans; Immunoglobulin M; Leukemia, Lymphoid; Lymphocyte Culture Test, Mixed; Mice; Mice, Inbred A; Phorbols; Rabbits; Receptors, Antigen, B-Cell; Tetradecanoylphorbol Acetate | 1982 |
In vitro modulation of oncogenesis and differentiation by retinoids and tumor promoters.
Topics: Adenosine Triphosphatases; Animals; Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Cocarcinogenesis; Cricetinae; Embryo, Mammalian; Mice; Phorbols; Retinol-Binding Proteins; Sister Chromatid Exchange; Tetradecanoylphorbol Acetate; Tretinoin; X-Rays | 1982 |
Transformation and tumor promoter sensitive phosphoproteins in JB-6 mouse epidermal cells: one is also sensitive to heat stress.
Topics: Animals; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Epidermis; Hot Temperature; Mice; Molecular Weight; Phosphoproteins; Phosphorylation; Proteins; Tetradecanoylphorbol Acetate | 1984 |
Chronic application of a tumor promoter to confluent nontransformed rat cells induces the irreversible expression of transformed phenotype.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Clone Cells; Female; Phenotype; Phorbols; Pregnancy; Rats; Rats, Inbred F344; Tetradecanoylphorbol Acetate; Time Factors | 1984 |
The transformation of a rat cell line induced by a tumor promoter occurs without affecting sister chromatid exchange.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Crossing Over, Genetic; Female; Phenotype; Phorbols; Pregnancy; Rats; Rats, Inbred F344; Sister Chromatid Exchange; Tetradecanoylphorbol Acetate | 1984 |
Susceptibility of skin fibroblasts from individuals genetically predisposed to cancer, to transformation by the tumour promoter 12-O-tetradecanoylphorbol-13-acetate.
Topics: Adult; Animals; Cell Division; Cell Line; Cell Movement; Cell Transformation, Neoplastic; Cells, Cultured; Child; Child, Preschool; Colonic Polyps; Eye Neoplasms; Female; Fetus; Fibroblasts; Humans; Infant; Male; Mice; Mice, Nude; Middle Aged; Neoplasm Transplantation; Phorbols; Pregnancy; Retinoblastoma; Skin; Tetradecanoylphorbol Acetate; Transplantation, Heterologous | 1984 |
Role of free radicals in the initiation and promotion of radiation transformation in vitro.
Topics: Animals; Catalase; Cell Transformation, Neoplastic; Free Radicals; Hydrogen Peroxide; Mice; Salicylates; Superoxide Dismutase; Tetradecanoylphorbol Acetate | 1984 |
Effects of agents known to antagonize the enhancement of in vitro transformation by 12-tetradecanoyl-phorbol-13-acetate (TPA) on the TPA suppression of metabolic cooperation.
Topics: Animals; Antipain; Cell Communication; Cell Line; Cell Transformation, Neoplastic; Cricetinae; Oligopeptides; Phorbols; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Tretinoin; Trypsin Inhibitors | 1984 |
Role of specific membrane and genetic changes in the mechanism of tumour promotion. Studies with promoter-resistant variants.
Topics: Animals; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Clone Cells; DNA, Neoplasm; Drug Resistance; Gangliosides; Genes; Genetic Variation; Mice; Rats; Skin; Tetradecanoylphorbol Acetate; Transfection | 1984 |
Modulation by retinyl acetate of microfilament bundle formation in C3H/10T1/2 cells.
Topics: Actins; Animals; Cell Adhesion; Cell Line; Cell Transformation, Neoplastic; Cytoskeleton; Diterpenes; Mice; Microscopy, Electron; Retinyl Esters; Tetradecanoylphorbol Acetate; Vitamin A | 1984 |
Induction of cytotoxic effector activity in the HL-60 promyelocytic cell line by incubation with phorbol myristate acetate: a model system of human spontaneous monocyte-mediated cytotoxicity.
Topics: Animals; Antimetabolites; Cell Line; Cell Transformation, Neoplastic; Cellobiose; Chickens; Cytotoxicity, Immunologic; Disaccharides; Humans; Kinetics; Leukemia, Myeloid, Acute; Models, Biological; Monocytes; Tetradecanoylphorbol Acetate | 1983 |
Differentiation of HL-60 cells: cell volume and cell cycle changes.
Topics: Butyrates; Butyric Acid; Cell Count; Cell Cycle; Cell Transformation, Neoplastic; Dimethyl Sulfoxide; Flow Cytometry; Humans; Leukemia, Myeloid, Acute; Macrophages; Tetradecanoylphorbol Acetate; Tretinoin | 1983 |
Nonspecific esterases of leukemia cell lines: evidence for activation of myeloid-associated zymogens in HL-60 by phorbol esters.
Topics: Cell Line; Cell Transformation, Neoplastic; Enzyme Activation; Enzyme Precursors; Esterases; Humans; Isoenzymes; Leukemia, Myeloid; Phorbols; Tetradecanoylphorbol Acetate | 1984 |
Phenotypic modulation of chronic lymphocytic leukemia cells by phorbol ester: induction of IgM secretion and changes in the expression of B cell-associated surface antigens.
Topics: Antigens, Neoplasm; Antigens, Surface; B-Lymphocytes; Cell Differentiation; Cell Transformation, Neoplastic; Humans; Immunoglobulin M; Kinetics; Leukemia, Lymphoid; Phenotype; Phorbols; Receptors, Antigen, B-Cell; Tetradecanoylphorbol Acetate | 1984 |
Alteration of the chemotactic response of NIH/3T3 cells to PDGF by growth factors, transformation, and tumor promoters.
Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Chemotaxis; Epidermal Growth Factor; Epithelium; Fibroblast Growth Factors; Fibroblasts; Growth Substances; Kirsten murine sarcoma virus; Mice; Phorbols; Platelet-Derived Growth Factor; Tetradecanoylphorbol Acetate | 1984 |
Inhibition of radiation-initiated and -promoted transformation of Syrian hamster embryo cells by lymphotoxin.
Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Embryo, Mammalian; Galactose; Kinetics; Lymphotoxin-alpha; Mesocricetus; Tetradecanoylphorbol Acetate | 1984 |
Reduced trisialoganglioside synthesis in chemically but not mos-transformed mouse epidermal cells.
Topics: Animals; Carbon Radioisotopes; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Diterpenes; Epidermal Growth Factor; Gangliosides; Glucosamine; Mice; Phorbol Esters; Phorbols; Skin; Terpenes; Tetradecanoylphorbol Acetate | 1984 |
Partial purification and characterization of a BCGFII from EL4 culture supernatants.
Topics: Animals; B-Lymphocytes; Cell Line; Cell Transformation, Neoplastic; Chromatography, Gel; Chromatography, Ion Exchange; Growth Substances; Interleukin-4; Isoelectric Focusing; Kinetics; Lymphocyte Activation; Lymphokines; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Tetradecanoylphorbol Acetate | 1984 |
The effects of tumor-promoting phorbol esters on human granulopoiesis in vitro.
Topics: Bone Marrow; Bone Marrow Cells; Cell Transformation, Neoplastic; Colony-Forming Units Assay; Colony-Stimulating Factors; Granulocytes; Hematopoiesis; Hematopoietic Stem Cells; Humans; Macrophages; Monocytes; Phorbol Esters; Phorbols; Tetradecanoylphorbol Acetate | 1984 |
Distinctive phorbol ester-induced morphological and surface antigen changes in mycosis fungoides, the Sézary syndrome, and adult T-cell leukemia.
Topics: Adult; Antigens, Surface; Cell Transformation, Neoplastic; Cells, Cultured; Humans; Kinetics; Leukemia; Mycosis Fungoides; Phenotype; Phorbols; Sezary Syndrome; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1984 |
Factors that modify in vitro transformation.
Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Culture Media; Humans; Mesocricetus; Mice; Phytohemagglutinins; Tetradecanoylphorbol Acetate | 1983 |
Malignant transformation of epithelial cells in culture.
Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Chromosome Aberrations; Epithelium; Humans; Mice; Skin; Tetradecanoylphorbol Acetate | 1983 |
Transfer of phorbol ester promotability by transfection of DNA from promotable into nonpromotable cells.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Mice; Mice, Inbred BALB C; Phorbols; Skin; Tetradecanoylphorbol Acetate; Transfection | 1983 |
In vitro studies of the possible mechanisms whereby tumour promoters mediate their responses.
Topics: Carcinogens; Cell Movement; Cell Transformation, Neoplastic; Cells, Cultured; Chromosome Aberrations; Colonic Neoplasms; Eye Neoplasms; Fibroblasts; Humans; Methylnitronitrosoguanidine; Mutation; Retinoblastoma; Skin; Tetradecanoylphorbol Acetate | 1983 |
Enhanced sensitivity of the C3H/10T1/2 cell transformation system to alkylating and chemotherapeutic agents by treatment with 12-O-tetradecanoylphorbol-13-acetate.
Topics: Alkylating Agents; Animals; Antineoplastic Agents; Cell Transformation, Neoplastic; Cells, Cultured; Fibroblasts; Mice; Phorbols; Tetradecanoylphorbol Acetate | 1984 |
Transformation of cultured epithelial cells by ethylnitrosourea. Altered expression of type I procollagen chains.
Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Epithelium; Ethylnitrosourea; Kinetics; Macromolecular Substances; Molecular Weight; Nitrosourea Compounds; Peptides; Procollagen; Rats; Tetradecanoylphorbol Acetate | 1984 |
[Effect of tumor promoting agents on the in vitro malignant transformation of the fetal rat brain cells exposed in utero to ethylnitrosourea].
Topics: Animals; Brain Neoplasms; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Drug Interactions; Ethylnitrosourea; Female; Fetus; In Vitro Techniques; Maternal-Fetal Exchange; Nitrosourea Compounds; Phenobarbital; Phorbols; Pregnancy; Rats; Tetradecanoylphorbol Acetate | 1984 |
Properties of cell lots suitable for focus assay in the chemical transformation of Syrian hamster cells in culture.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Drug Evaluation, Preclinical; Mesocricetus; Tetradecanoylphorbol Acetate | 1980 |
Protease inhibitor antipain suppresses 12-O-tetradecanoyl-phorbol-13-acetate induction of plasminogen activator in transformable mouse embryo fibroblasts.
Topics: Animals; Antipain; Cell Transformation, Neoplastic; Cells, Cultured; Enzyme Induction; Female; Fibroblasts; Leupeptins; Mice; Oligopeptides; Phorbols; Plasminogen Activators; Plasminogen Inactivators; Pregnancy; Tetradecanoylphorbol Acetate; Time Factors; Trypsin Inhibitor, Bowman-Birk Soybean | 1981 |
Effects of teleocidin and the phorbol ester tumor promoters on cell transformation, differentiation, and phospholipid metabolism.
Topics: Adenoviruses, Human; Alkaloids; Animals; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Choline; Humans; Lyngbya Toxins; Melanins; Melanoma; Mice; Muscles; Phorbols; Phospholipids; Rats; Tetradecanoylphorbol Acetate | 1982 |
Initiation of C3H/10T1/2 cell transformation by N-methyl-N'-nitro-N-nitrosoguanidine and aflatoxin B1.
Topics: Aflatoxin B1; Aflatoxins; Animals; Cell Line; Cell Transformation, Neoplastic; Methylcholanthrene; Methylnitronitrosoguanidine; Mice; Tetradecanoylphorbol Acetate | 1982 |
TPA affects early and late stages of chemically-induced transformation in mouse submandibular salivary epithelial cells in vitro.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Dimethyl Sulfoxide; Epithelial Cells; Epithelium; Male; Mice; Phenotype; Phorbols; Submandibular Gland; Tetradecanoylphorbol Acetate; Thymidine; Time Factors | 1983 |
Hexose uptake as an indicator of JB6 mouse epidermal cell resistance to the mitogenic activity of TPA.
Topics: Animals; Biological Transport, Active; Cell Division; Cell Line; Cell Transformation, Neoplastic; Deoxy Sugars; Deoxyglucose; Drug Resistance; Epidermis; Interphase; Kinetics; Mice; Mitogens; Phorbols; Tetradecanoylphorbol Acetate | 1983 |
The nuclear-associated endoplasmic reticulum is an early target for the action of the tumor promoter 12-O-tetradecanoyl phorbol-13-acetate in C3H/10T1/2 fibroblasts.
Topics: Animals; Cell Nucleus; Cell Transformation, Neoplastic; Cells, Cultured; Choline; Endoplasmic Reticulum; Intracellular Membranes; Membrane Lipids; Mice; Phorbols; Tetradecanoylphorbol Acetate | 1983 |
Prevention of hereditary large bowel cancer: tissue culture assays and logistics.
Topics: Actins; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Colonic Neoplasms; Humans; Oncogenic Viruses; Rectal Neoplasms; Tetradecanoylphorbol Acetate | 1983 |
Increased DNA content as an early marker of transformation in carcinogen-exposed rat tracheal cell cultures.
Topics: Aneuploidy; Animals; Cell Transformation, Neoplastic; DNA; Interphase; Male; Methylnitronitrosoguanidine; Rats; Rats, Inbred F344; Tetradecanoylphorbol Acetate; Trachea | 1983 |
Factors influencing the promotion of transformation in chemically-initiated C3H/10T1/2 Cl 8 mouse embryo fibroblasts.
Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Female; Fibroblasts; Methylnitronitrosoguanidine; Mice; Mice, Inbred C3H; Phorbols; Pregnancy; Tetradecanoylphorbol Acetate; Time Factors | 1983 |
Growth stimulation and tumor promotion in skin.
Topics: Animals; Cell Division; Cell Transformation, Neoplastic; Mice; Phorbol Esters; Phorbols; Prostaglandins; Skin; Tetradecanoylphorbol Acetate | 1983 |
Transformation of epidermal cells in culture.
Topics: Animals; Calcium; Cell Transformation, Neoplastic; Cells, Cultured; DNA Replication; Epidermal Cells; Epidermis; Mice; Mice, Inbred BALB C; Tetradecanoylphorbol Acetate | 1983 |
Ornithine decarboxylase activity and DNA synthesis in primary and transformed hamster epidermal cells exposed to tumor promoter.
Topics: Animals; Animals, Newborn; Carboxy-Lyases; Cell Cycle; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; DNA Replication; Kinetics; Mesocricetus; Ornithine Decarboxylase; Phorbols; Skin; Tetradecanoylphorbol Acetate | 1983 |
Ornithine decarboxylase induction by chemically complex liquids from two solvent refined coal processes.
Topics: Animals; Carboxy-Lyases; Cell Transformation, Neoplastic; Coal; Enzyme Induction; Female; Kinetics; Mice; Ornithine Decarboxylase; Skin; Solvents; Tetradecanoylphorbol Acetate | 1983 |
Onion and garlic oils inhibit tumor promotion.
Topics: Animals; Cell Transformation, Neoplastic; Drug Antagonism; Female; Garlic; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Oils; Phorbols; Plants, Medicinal; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1983 |
Role of intercellular communication in the promotion of C3H/10T1/2 cell transformation.
Topics: Animals; Cell Communication; Cell Transformation, Neoplastic; Cells, Cultured; Dose-Response Relationship, Drug; Kinetics; Mice; Mice, Inbred C3H; Phorbols; Ribonucleotides; Tetradecanoylphorbol Acetate; Transcription, Genetic; Uridine | 1983 |
Transfer of sensitivity to tumor promoters by transfection of DNA from sensitive into insensitive mouse JB6 epidermal cells.
Topics: Animals; Cell Adhesion; Cell Transformation, Neoplastic; Clone Cells; DNA; Mice; Phenotype; Skin; Tetradecanoylphorbol Acetate; Transfection | 1983 |
Differentiation of human leukemias in response to 12-0-tetradecanoylphorbol-13-acetate in vitro.
Topics: Cell Adhesion; Cell Aggregation; Cell Transformation, Neoplastic; Esterases; Humans; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Phagocytosis; Phorbols; Tetradecanoylphorbol Acetate | 1980 |
Decreased membrane fluidity during differentiation of human promyelocytic leukemia cells in culture.
Topics: Cell Membrane; Cell Transformation, Neoplastic; Cells, Cultured; Cholesterol; Dimethyl Sulfoxide; Humans; Leukemia, Myeloid, Acute; Membrane Lipids; Phospholipids; Tetradecanoylphorbol Acetate | 1980 |
Early changes in phosphatidylcholine metabolism in human acute promyelocytic leukemia cells stimulated to differentiate by phorbol ester.
Topics: Cell Transformation, Neoplastic; Humans; Leukemia, Myeloid, Acute; Methylation; Phorbol Esters; Phorbols; Phosphatidylcholines; Phospholipids; Tetradecanoylphorbol Acetate; Time Factors | 1981 |
Retinoids inhibit promoter-dependent preneoplastic progression in mouse epidermal cell lines.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Mice; Phorbols; Skin; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Tretinoin | 1981 |
Modulation of terminal differentiation and responses to tumor promoters by retinoids in mouse epidermal cell cultures.
Topics: Animals; Cell Differentiation; Cell Division; Cell Line; Cell Transformation, Neoplastic; Enzyme Induction; Mice; Ornithine Decarboxylase; Phorbols; Skin; Tetradecanoylphorbol Acetate; Tretinoin | 1981 |
Terminal differentiation surface antigens of myelomonocytic cells are expressed in human promyelocytic leukemia cells (HL60) treated with chemical inducers.
Topics: Animals; Antibodies, Monoclonal; Antigens, Surface; Blood Cells; Bone Marrow; Bone Marrow Cells; Cell Transformation, Neoplastic; Dimethyl Sulfoxide; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Mice; Rabbits; Tetradecanoylphorbol Acetate; Tretinoin | 1981 |
Dissociation of mitogenesis and late-stage promotion of tumor cell phenotype by phorbol esters: mitogen-resistant variants are sensitive to promotion.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Clone Cells; Colchicine; Drug Resistance; Genetic Variation; Mice; Mitogens; Phenotype; Phorbols; Skin; Tetradecanoylphorbol Acetate | 1981 |
Release of platelet-activating factor from HL-60 human leukemic cells following macrophage-like differentiation.
Topics: Cell Line; Cell Transformation, Neoplastic; Humans; Leukemia, Myeloid, Acute; Leukocytes; Lysophosphatidylcholines; Macrophages; Platelet Activating Factor; Receptors, Complement; Tetradecanoylphorbol Acetate | 1982 |
Resting state depth and saturation density as modulated by tumor promoters and culture conditions: relationship to chemical transformation in C3H/10T1/2 cells.
Topics: Animals; Carcinogens; Cell Count; Cell Cycle; Cell Line; Cell Transformation, Neoplastic; Mice; Mice, Inbred C3H; Phorbols; Saccharin; Tetradecanoylphorbol Acetate | 1982 |
Ganglioside changes induced by tumor promoters in promotable JB6 mouse epidermal cells: antagonism by an antipromoter.
Topics: Animals; Cell Division; Cell Line; Cell Transformation, Neoplastic; Epidermis; Gangliosides; Mice; Phorbols; Tetradecanoylphorbol Acetate; Time Factors; Tretinoin | 1982 |
Tumor-promoter-resistant cells lack trisialoganglioside response.
Topics: Animals; Cell Adhesion; Cell Division; Cell Line; Cell Transformation, Neoplastic; Drug Resistance; Gangliosides; Membrane Fluidity; Mice; Phorbol Esters; Phorbols; Tetradecanoylphorbol Acetate | 1982 |
Inhibition by tumor-promoting phorbol esters of procollagen synthesis in promotable JB6 mouse epidermal cells.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Epidermis; Mice; Phorbol Esters; Phorbols; Procollagen; Tetradecanoylphorbol Acetate; Tretinoin | 1982 |
Variant cell lines from the human promyelocyte line HL60.
Topics: Cell Division; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Clone Cells; Dimethyl Sulfoxide; Humans; Karyotyping; Leukemia, Myeloid, Acute; Microscopy, Electron; Phenotype; Tetradecanoylphorbol Acetate | 1982 |
Modulation of phagocytosis by tumor promoters and epidermal growth factor in normal and transformed macrophages.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Diterpenes; Epidermal Growth Factor; Erythrocytes; Female; In Vitro Techniques; Macrophages; Mice; Microscopy, Electron, Scanning; Peptides; Phagocytosis; Phorbols; Pyran Copolymer; Tetradecanoylphorbol Acetate; Thioglycolates | 1980 |
Regulation of gene expression by tumor promoters. II. Control of cell shape and developmental programs for macrophages and granulocytes in human myeloid leukemic cells.
Topics: Carcinogens; Cell Line; Cell Transformation, Neoplastic; Colony-Stimulating Factors; Cytoplasm; Dimethyl Sulfoxide; Gene Expression Regulation; Granulocytes; Humans; Leukemia, Myeloid; Macrophages; Neoplasm Proteins; Tetradecanoylphorbol Acetate | 1981 |
Neutrophil migration inhibition factor from T lymphocytes (NIF-T): selective removal of biologic activity by human peripheral blood neutrophils, myelocytic leukemia cells, and differentiated HL-60 cells.
Topics: Animals; Cell Line; Cell Membrane; Cell Movement; Cell Transformation, Neoplastic; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Formaldehyde; Horses; Humans; Isoelectric Focusing; Leukemia, Myeloid; Lymphokines; Mice; Mice, Inbred Strains; Neutrophils; Rabbits; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1982 |
Expression of initiated and promoted stages of irradiation carcinogenesis in vitro.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Cocarcinogenesis; Cricetinae; Embryo, Mammalian; Lymphotoxin-alpha; Mesocricetus; Neoplasms, Radiation-Induced; Phenotype; Tetradecanoylphorbol Acetate; Time Factors; Ultraviolet Rays; X-Rays | 1981 |
Promotion of x-ray transformation in vitro.
Topics: Animals; Anti-Inflammatory Agents; Cell Count; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cocarcinogenesis; DNA Repair; Epidermal Growth Factor; Mice; Mitomycins; Mutation; Phorbols; Radiation, Ionizing; Tetradecanoylphorbol Acetate; X-Rays | 1982 |
Studies on antagonistic actions of TPA and retinoic acid.
Topics: Animals; Cell Adhesion; Cell Division; Cell Line; Cell Transformation, Neoplastic; Clone Cells; Contact Inhibition; Epidermal Growth Factor; Mice; Phorbols; Tetradecanoylphorbol Acetate; Tretinoin | 1982 |
Lymphotoxin enhances the susceptibility of neoplastic and preneoplastic cells to natural killer cell mediated destruction.
Topics: Animals; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cytotoxicity, Immunologic; Guinea Pigs; Humans; Immunity, Innate; Killer Cells, Natural; Leukocytes; Lymphotoxin-alpha; Precancerous Conditions; Tetradecanoylphorbol Acetate | 1982 |
A phorbol ester tumor promoter induces changes in the expression of immunoglobulins and DR antigens in human lymphoblastoid cells.
Topics: Antibody-Producing Cells; B-Lymphocytes; Cell Line; Cell Transformation, Neoplastic; Histocompatibility Antigens Class II; HLA-DR Antigens; Humans; Immunoglobulin D; Immunoglobulin M; Immunoglobulins; Lymphocyte Activation; Phorbols; Receptors, Antigen, B-Cell; Tetradecanoylphorbol Acetate | 1982 |
The effect of lentinan on production of interleukin-1 by human monocytes.
Topics: Adjuvants, Immunologic; Animals; Cell Transformation, Neoplastic; Humans; Interleukin-1; Lentinan; Leukemia, Myeloid; Lymphocyte Activation; Mice; Mice, Inbred C3H; Monocytes; Phytohemagglutinins; Polysaccharides; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1982 |
Phytohemagglutinin inhibits phorbol diester promotion of UV-irradiation initiated transformation in Syrian hamster embryo cells.
Topics: Agglutinins; Animals; Cell Transformation, Neoplastic; Concanavalin A; Cricetinae; Galactose; Leukocytes; Lymphotoxin-alpha; Neoplasms, Radiation-Induced; Phorbols; Phytohemagglutinins; Tetradecanoylphorbol Acetate | 1982 |
Selective effects of phorbol 12-myristate 13-acetate on myofibrils and 10-nm filaments.
Topics: Animals; Cell Transformation, Neoplastic; Chick Embryo; Fluorescent Antibody Technique; Microscopy, Fluorescence; Muscles; Myofibrils; Myosin Subfragments; Phorbols; Tetradecanoylphorbol Acetate | 1980 |
Differential response of premalignant epithelial cell classes to phorbol ester tumor promoters and to deoxycholic acid.
Topics: Cell Division; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Colonic Neoplasms; Deoxycholic Acid; DNA Replication; Epithelium; Humans; Peptide Hydrolases; Phorbols; Plasminogen Activators; Precancerous Conditions; Protease Inhibitors; Tetradecanoylphorbol Acetate | 1981 |
On deciding which factors regulate cell growth.
Topics: Animals; Caffeine; Cell Cycle; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Cycloheximide; Epidermal Growth Factor; Humans; Insulin; Kinetics; Lectins; Mutation; Tetradecanoylphorbol Acetate; Thrombin | 1981 |
Phorbol ester-induced differentiation of a non-T, non-B leukemic cell line: model for human lymphoid progenitor cell development.
Topics: Adolescent; Antibodies, Monoclonal; Antigens, Neoplasm; Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; DNA Nucleotidylexotransferase; Female; Fluorescent Antibody Technique; Histocompatibility Antigens Class II; Humans; Leukemia, Lymphoid; Lymphocytes; Phenotype; Phorbols; Tetradecanoylphorbol Acetate | 1982 |
Cell competence for industion of differentiation by insulin and other compounds in myeloid leukemic clones continuously cultured in serum-free medium.
Topics: Animals; Cell Differentiation; Cell Transformation, Neoplastic; Clone Cells; Colony-Stimulating Factors; Culture Media; Dexamethasone; Hematopoietic Stem Cells; Insulin; Leukemia, Myeloid; Mice; Mice, Inbred Strains; Muramidase; Tetradecanoylphorbol Acetate; Transferrin | 1982 |
Enhanced transformation of mouse 10T1/2 cells by 12-O-tetradecanoylphorbol-13-acetate following exposure to X-rays or to fission-spectrum neutrons.
Topics: Animals; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Cocarcinogenesis; Fast Neutrons; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Neoplasms, Radiation-Induced; Neutrons; Phorbols; Radiation Dosage; Tetradecanoylphorbol Acetate; X-Rays | 1982 |
Effects of tumor-promoting phorbol diesters on neoplastic progression of Syrian hamster embryo cells.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Cricetinae; Embryo, Mammalian; Mesocricetus; Neoplasms, Experimental; Ornithine Decarboxylase; Phorbol Esters; Phorbols; Polyamines; Precancerous Conditions; Tetradecanoylphorbol Acetate | 1982 |
Effects of retinoic acid and tumor promoter 12-o-tetradecanoylphorbol-13-acetate (TPA) on the cell cycle of HeLa cells.
Topics: Cell Cycle; Cell Division; Cell Transformation, Neoplastic; DNA; Drug Interactions; Flow Cytometry; HeLa Cells; Humans; Mitosis; Phorbols; Tetradecanoylphorbol Acetate; Thymidine; Tretinoin | 1982 |
Derangement of regulation of protein degradation in transforming fibroblasts.
Topics: Animals; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Fibroblasts; Kinetics; Mice; Proteins; Tetradecanoylphorbol Acetate | 1982 |
The role of mitogenic stimulation and specific glycoprotein changes in the mechanism of late-stage promotion in JB-6 epidermal cell lines.
Topics: Animals; Cell Adhesion; Cell Line; Cell Transformation, Neoplastic; Epidermis; Mice; Mitogens; Phorbols; Procollagen; Tetradecanoylphorbol Acetate; Tretinoin | 1982 |
Genetic forms of neoplasia in man: a model for the study of tumor promotion in vitro.
Topics: Adenoma; Bile Acids and Salts; Cell Adhesion; Cell Cycle; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Cocarcinogenesis; DNA; Dose-Response Relationship, Drug; Fibroblasts; Humans; Intestinal Neoplasms; Mutation; Phorbols; Skin; Tetradecanoylphorbol Acetate; Thymidine | 1982 |
Regulation of mammalian cell transformation.
Topics: Animals; Antipain; Caffeine; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Cocarcinogenesis; Cricetinae; DNA Repair; Lymphokines; Methylnitronitrosoguanidine; Mutation; Sister Chromatid Exchange; Tetradecanoylphorbol Acetate; Ultraviolet Rays; X-Rays | 1982 |
Tumor promotion by regenerative epidermal hyperplasia in mouse skin.
Topics: Animals; Cell Transformation, Neoplastic; Hyperplasia; Mice; Regeneration; Skin; Skin Neoplasms; Skin Physiological Phenomena; Tetradecanoylphorbol Acetate | 1982 |
Isolation of methylcholanthrene-"initiated" C3H/10T1/2 cells by inhibiting neoplastic progression with retinyl acetate.
Topics: Animals; Cell Line; Cell Separation; Cell Transformation, Neoplastic; Cocarcinogenesis; Contact Inhibition; Diterpenes; Methylcholanthrene; Mice; Mice, Inbred C3H; Mice, Nude; Neoplasm Transplantation; Retinyl Esters; Tetradecanoylphorbol Acetate; Vitamin A | 1982 |
Inhibition of respiration by a phorbol ester tumor promoter in murine cultured cells.
Topics: Animals; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cell Line; Cell Transformation, Neoplastic; Embryo, Mammalian; Fibroblasts; Methylcholanthrene; Mice; Mice, Inbred C3H; Oligomycins; Oxygen Consumption; Phorbols; Tetradecanoylphorbol Acetate | 1982 |
Enhancement of altered-cell foci in baby mouse skin cultures by antitubulin treatment: nuclear mechanisms.
Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Colchicine; Cytochalasin D; Cytochalasins; Demecolcine; DNA; Light; Mice; Oxygen; Polyploidy; Skin; Tetradecanoylphorbol Acetate | 1982 |
Surface antigens of melanocytes and melanomas. Markers of melanocyte differentiation and melanoma subsets.
Topics: Adult; Animals; Antibodies, Monoclonal; Antigens, Neoplasm; Antigens, Surface; Cell Differentiation; Cell Transformation, Neoplastic; Cholera Toxin; Female; Humans; Infant, Newborn; Melanoma; Mice; Pregnancy; Skin; Tetradecanoylphorbol Acetate | 1982 |
Tumor promoter induces loss of anchorage dependence in human skin fibroblasts from individuals genetically predisposed to cancer.
Topics: Adenoma; Agar; Animals; Cell Transformation, Neoplastic; Cells, Cultured; Colonic Neoplasms; Fibroblasts; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Phorbols; Rectal Neoplasms; Skin; Tetradecanoylphorbol Acetate | 1980 |
Effect of 12-O-tetradecanoylphorbol-13-acetate on two charateristics of transformation acquired sequentially by ENU-exposed rat brain cells.
Topics: Agar; Animals; Brain; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Ethylnitrosourea; Phorbols; Plasminogen Activators; Rats; Tetradecanoylphorbol Acetate | 1980 |
Cell culture tumor promotion experiments with saccharin, phorbol myristate acetate and several common food materials.
Topics: Animals; Ascorbic Acid; Cell Transformation, Neoplastic; Cells, Cultured; Mice; Pantothenic Acid; Phorbols; Saccharin; Tetradecanoylphorbol Acetate; Tryptophan | 1980 |
Effects of tumor promoters and extracellular calcium on the growth of normal, transformed and temperature sensitive rat liver epithelial cells.
Topics: Animals; Calcium; Cell Line; Cell Transformation, Neoplastic; Epithelium; Liver; Mutation; Phorbols; Rats; Temperature; Tetradecanoylphorbol Acetate | 1980 |
Chemical carcinogenesis studies in mouse epidermal cell cultures.
Topics: Animals; Carcinogens; Cell Differentiation; Cell Transformation, Neoplastic; Cells, Cultured; Environmental Exposure; Enzyme Induction; Epidermal Cells; Epidermis; Methylnitronitrosoguanidine; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin | 1980 |
Enhancement of carcinogenesis in cultured respiratory tract epithelium by 12-0-tetradecanoylphorbol-13-acetate.
Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Epithelium; Female; Methylnitronitrosoguanidine; Neoplasms, Experimental; Phorbols; Rats; Tetradecanoylphorbol Acetate; Time Factors; Trachea; Tracheal Neoplasms | 1980 |
Initiation of C3H/10T1/2 cell transformation by formaldehyde.
Topics: Animals; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Drug Interactions; Formaldehyde; Formates; Methanol; Mice; Phorbols; Tetradecanoylphorbol Acetate | 1981 |
Initiator and promoter induced specific changes in epidermal function and biological potential.
Topics: Animals; Animals, Newborn; Calcium; Cell Differentiation; Cell Transformation, Neoplastic; Cells, Cultured; Enzyme Induction; Kinetics; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Ornithine Decarboxylase; Phorbols; Skin; Skin Physiological Phenomena; Tetradecanoylphorbol Acetate | 1981 |
Chemical transformation of cultured skin fibroblasts from humans genetically predisposed to cancer.
Topics: Cell Transformation, Neoplastic; Cells, Cultured; Fibroblasts; Gardner Syndrome; Humans; Methylnitronitrosoguanidine; Skin; Tetradecanoylphorbol Acetate | 1981 |
An in vitro model of pancreas carcinogenesis: two-stage MNU--TPA effect.
Topics: Animals; Cell Transformation, Neoplastic; Hyperplasia; Methylnitrosourea; Mice; Mice, Nude; Models, Biological; Necrosis; Neoplasm Transplantation; Nitrosourea Compounds; Organ Culture Techniques; Pancreas; Pancreatic Neoplasms; Phorbols; Rats; Tetradecanoylphorbol Acetate; Transplantation, Heterologous | 1980 |
Effect of time and duration of exposure to 12-O-tetradecanoylphorbol-13-acetate on x-ray transformation of C3H 10T 1/2 cells.
Topics: Animals; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Cocarcinogenesis; Mice; Phorbols; Tetradecanoylphorbol Acetate; Time Factors; X-Rays | 1980 |
Regulation of polyamine biosynthesis in normal and transformed hamster cells in culture.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Cricetinae; Enzyme Induction; Fibroblasts; Ornithine Decarboxylase; Phorbols; Polyamines; Putrescine; Spermidine; Spermine; Tetradecanoylphorbol Acetate | 1980 |
Induction of tumor cytostatic macrophages by 12-0-tetradecanoyl phorbol-13-acetate (TPA).
Topics: Animals; Cell Transformation, Neoplastic; Cytoplasmic Granules; Growth Inhibitors; Hexosephosphates; Lymphoma; Macrophages; Mice; Mice, Inbred C57BL; Pinocytosis; Tetradecanoylphorbol Acetate; Thymidine; Time Factors | 1980 |
Modification of sister chromatid exchanges and radiation-induced transformation in rodent cells by the tumor promoter 12-O-tetradecanoylphorbol-13-acetate and two retinoids.
Topics: Animals; Cell Division; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; Cocarcinogenesis; Cricetinae; Crossing Over, Genetic; Mice; Phorbols; Sister Chromatid Exchange; Tetradecanoylphorbol Acetate; Tretinoin | 1981 |
Demonstration by DNA fingerprint analysis of genomic instability in mouse BALB 3T3 cells during cell transformation.
Topics: 3T3 Cells; Animals; Base Sequence; Cell Line, Transformed; Cell Transformation, Neoplastic; Cloning, Molecular; DNA Damage; DNA Fingerprinting; DNA Probes; DNA, Satellite; Methylcholanthrene; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Mutagenesis; Mutagens; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 1994 |
12-O-tetradecanoylphorbol-13-acetate promotion of transgenic mice expressing epidermal-targeted v-fos induces rasHA-activated papillomas and carcinomas without p53 mutation: association of v-fos expression with promotion and tumor autonomy.
Topics: Animals; Base Sequence; Biomarkers; Carcinoma; Cell Differentiation; Cell Transformation, Neoplastic; DNA, Neoplasm; Epidermis; Gene Expression Regulation, Neoplastic; Genes, fos; Genes, p53; Genes, ras; Hyperplasia; Keratins; Keratosis; Mice; Mice, Transgenic; Molecular Sequence Data; Mutation; Oncogene Proteins v-fos; Papilloma; ras Proteins; RNA, Neoplasm; Tetradecanoylphorbol Acetate | 1995 |
Effects of curcumin, demethoxycurcumin, bisdemethoxycurcumin and tetrahydrocurcumin on 12-O-tetradecanoylphorbol-13-acetate-induced tumor promotion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Cell Line; Cell Transformation, Neoplastic; Coumaric Acids; Curcumin; Diarylheptanoids; Dose-Response Relationship, Drug; Enzyme Induction; Female; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; Skin; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Time Factors | 1995 |
Genetic alterations cooperate with v-Ha-ras to accelerate multistage carcinogenesis in TG.AC transgenic mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Base Composition; Base Sequence; Carcinoma, Squamous Cell; Cell Division; Cell Transformation, Neoplastic; Cocarcinogenesis; Diglycerides; Female; Fibrosarcoma; Genes, p53; Genes, ras; Mice; Mice, Transgenic; Molecular Sequence Data; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1995 |
Benzoyl peroxide acts as a promoter of radiation induced malignant transformation in vitro.
Topics: Animals; Ascorbic Acid; Benzoyl Peroxide; Cell Line; Cell Transformation, Neoplastic; Dose-Response Relationship, Radiation; Free Radicals; Hydroxyl Radical; Hydroxylation; Iron; Kinetics; Mice; Radiation-Sensitizing Agents; Tetradecanoylphorbol Acetate; X-Rays | 1995 |
Improvement in the efficiency of the in vitro transformation assay method using BALB/3T3 A31-1-1 cells.
Topics: 3T3 Cells; Animals; Cell Transformation, Neoplastic; Culture Media; Dimethylnitrosamine; Methylnitronitrosoguanidine; Mice; Tetradecanoylphorbol Acetate | 1995 |
Effects of the 6 beta-7 beta-epoxide of 12-O-tetradecanoyl-phorbol-13-acetate on radiation transformation in vitro.
Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Croton Oil; Epoxy Compounds; In Vitro Techniques; Mice; Tetradecanoylphorbol Acetate | 1995 |
v-erbA cooperates with bFGF in neuroretina cell transformation.
Topics: Animals; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Chick Embryo; Cloning, Molecular; Fibroblast Growth Factor 2; Genes, fos; Genes, gag; Genes, jun; Genes, ras; Insulin; Oncogene Proteins v-erbA; Oncogene Proteins v-raf; Oncogene Proteins, Viral; Oncogenes; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ets; Proto-Oncogenes; Proviruses; Receptor, ErbB-2; Retinal Ganglion Cells; Retroviridae Proteins, Oncogenic; RNA; Tetradecanoylphorbol Acetate; Transcription Factors | 1993 |
Elevated expression of protein tyrosine kinase c-Yes, but not c-Src, in human malignant melanoma.
Topics: Blotting, Western; Cell Transformation, Neoplastic; DNA Mutational Analysis; Humans; Melanocytes; Melanoma; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-yes; Proto-Oncogene Proteins pp60(c-src); Proto-Oncogenes; RNA, Messenger; src-Family Kinases; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Initiating activity of quinones in the two-stage transformation of BALB/3T3 cells.
Topics: 3T3 Cells; Animals; Carcinogens; Cell Survival; Cell Transformation, Neoplastic; Mice; Mice, Inbred BALB C; Quinones; Tetradecanoylphorbol Acetate | 1995 |
Induction of pseudofoci and inhibition of density-mediated neoplastic transformation by PMA in NIH 3T3 cells after short-term exposures.
Topics: 3T3 Cells; Animals; Cell Aggregation; Cell Count; Cell Division; Cell Transformation, Neoplastic; DNA; Mice; Phorbol Esters; Tetradecanoylphorbol Acetate | 1995 |
c-jun and multistage carcinogenesis: association of overexpression of introduced c-jun with progression toward a neoplastic endpoint in mouse JB6 cells sensitive to tumor promoter-induced transformation.
Topics: Animals; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Gene Expression; Genes, jun; Humans; Mice; Phenotype; Proto-Oncogene Proteins c-jun; RNA, Messenger; Sensitivity and Specificity; Skin; Skin Neoplasms; Skin Physiological Phenomena; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transfection | 1995 |
Expression of antisense osteopontin RNA inhibits tumor promoter-induced neoplastic transformation of mouse JB6 epidermal cells.
Topics: Animals; Carcinogens; Cell Line, Transformed; Cell Transformation, Neoplastic; Dexamethasone; DNA, Complementary; Mammary Tumor Virus, Mouse; Mice; Mice, Inbred BALB C; Osteopontin; Phosphoproteins; RNA, Antisense; Sialoglycoproteins; Tetradecanoylphorbol Acetate | 1995 |
Effects of okadaic acid on calcitriol- and phorbol ester-induced expression and phosphorylation of osteopontin in mouse JB6 epidermal cells.
Topics: Animals; Calcitriol; Cell Adhesion; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Ethers, Cyclic; Gene Expression; In Vitro Techniques; Mice; Okadaic Acid; Osteopontin; Phosphoproteins; Phosphorylation; RNA, Messenger; Sialoglycoproteins; Tetradecanoylphorbol Acetate | 1995 |
Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase gene expression in FRTL-5 cells. II. Down-regulation by v-K-ras oncogene.
Topics: Acetates; Activating Transcription Factor 2; Animals; Antibodies; Cell Line; Cell Line, Transformed; Cell Transformation, Neoplastic; Colforsin; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Gene Expression Regulation, Enzymologic; Genes, ras; Hydroxymethylglutaryl CoA Reductases; Kinetics; Kirsten murine sarcoma virus; Leucine Zippers; Moloney murine sarcoma virus; Mutagenesis; Protein Kinase C; Rats; RNA, Messenger; Temperature; Tetradecanoylphorbol Acetate; Thyroid Gland; Transcription Factors | 1995 |
[The role of TNF-alpha in the growth and differentiation of U937 cells induced by PMA and IFN-gamma].
Topics: Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Humans; Interferon-gamma; Leukemia, Monocytic, Acute; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1994 |
Differential expression of prostaglandin H synthase isozymes during multistage carcinogenesis in mouse epidermis.
Topics: Amino Acid Sequence; Animals; Carcinoma; Cell Transformation, Neoplastic; Cocarcinogenesis; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Isoenzymes; Keratinocytes; Mice; Molecular Sequence Data; Papilloma; Prostaglandin-Endoperoxide Synthases; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1995 |
Differential susceptibility of morphologically TPA-resistant and -sensitive Balb/c 3T3 variants to TPA-induced cell transformation: relationship to induction of membrane ruffling.
Topics: 3T3 Cells; Actins; Animals; Cell Membrane; Cell Transformation, Neoplastic; Contact Inhibition; DNA Replication; Mice; Phosphorylation; Platelet-Derived Growth Factor; Protein Kinase C; Tetradecanoylphorbol Acetate | 1994 |
Synergistic effects of chlordane and TPA in multistage morphological transformation of SHE cells.
Topics: Animals; Autoradiography; Carcinogens; Cell Communication; Cell Transformation, Neoplastic; Cells, Cultured; Chlordan; Cricetinae; DNA Adducts; Drug Synergism; Embryo, Mammalian; Mesocricetus; Phosphorus Radioisotopes; Tetradecanoylphorbol Acetate | 1995 |
Effects of retinoids, beta-carotene, and canthaxanthin on UV- and X-ray-induced transformation of C3H10T1/2 cells in vitro.
Topics: Animals; Antineoplastic Agents; beta Carotene; Canthaxanthin; Carotenoids; Cell Transformation, Neoplastic; Cells, Cultured; Mice; Mice, Inbred C3H; Retinoids; Tetradecanoylphorbol Acetate; Time Factors; Ultraviolet Rays; X-Rays | 1994 |
Modulation of phorbol ester-induced HL-60 differentiation by prostaglandin E2.
Topics: Carcinogenicity Tests; Carcinogens; Cell Differentiation; Cell Separation; Cell Transformation, Neoplastic; Dinoprostone; Dose-Response Relationship, Drug; Drug Synergism; Fibroblasts; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Leukemia; Phagocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Transformation-sensitive cells in G2/M-phase are not promoted by TPA following 137Cs gamma-rays.
Topics: Animals; Cell Transformation, Neoplastic; Cesium Radioisotopes; G2 Phase; Mice; Mice, Inbred C3H; Mitosis; Tetradecanoylphorbol Acetate | 1993 |
Preferential primary-response gene expression in promotion-resistant versus promotion-sensitive JB6 cells.
Topics: 3T3 Cells; Animals; Carcinogens; Cell Transformation, Neoplastic; DNA-Binding Proteins; Epidermal Growth Factor; Gene Expression; Genes; Immediate-Early Proteins; Mice; Mice, Inbred BALB C; Multigene Family; Proteins; Tetradecanoylphorbol Acetate; Tristetraprolin | 1994 |
Expression and function of connexin in normal and transformed human keratinocytes in culture.
Topics: Carcinoma, Squamous Cell; Cell Communication; Cell Line, Transformed; Cell Transformation, Neoplastic; Cells, Cultured; Connexins; Gap Junctions; Humans; Keratinocytes; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transfection | 1994 |
Proliferative responses of epithelial cells to 8-bromo-cyclic AMP and to a phorbol ester change during breast pathogenesis.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Biopsy; Breast; Breast Neoplasms; Cell Division; Cell Line; Cell Line, Transformed; Cell Transformation, Neoplastic; Cholera Toxin; Epithelium; Humans; Reference Values; Tetradecanoylphorbol Acetate; Time Factors | 1994 |
Modification of invasion and differentiation in human melanoma cell clones.
Topics: Cell Survival; Cell Transformation, Neoplastic; Chemotaxis; Doxorubicin; Humans; Melanoma; Neoplasm Invasiveness; Plasminogen Activators; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1994 |
Effect of curcumin on 12-O-tetradecanoylphorbol-13-acetate- and ultraviolet B light-induced expression of c-Jun and c-Fos in JB6 cells and in mouse epidermis.
Topics: Animals; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Cocarcinogenesis; Curcumin; Drug Interactions; Female; Gene Expression Regulation; Hyperplasia; Mice; Mice, Hairless; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 1994 |
Enhanced tumorigenesis by small, protracted doses of densely ionizing radiation.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Dose-Response Relationship, Radiation; G2 Phase; Mice; Mice, Inbred C3H; Neoplasms, Radiation-Induced; Radiation Dosage; Radiation, Ionizing; Radon; Tetradecanoylphorbol Acetate; Time Factors | 1994 |
[Inhibitory effect of a third generation retinoid R8923 and all-trans retinoic acid on two-stage chemical carcinogenesis of BALB/3T3-A31 cells in vitro].
Topics: 3T3 Cells; Animals; Antineoplastic Agents; Cell Transformation, Neoplastic; Methylcholanthrene; Mice; Mice, Inbred BALB C; Retinoids; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1994 |
Deficiency of tyrosine phosphorylation in a Balb/c 3T3 cell variant hypersensitive to phorbol ester-induced cell transformation.
Topics: 3T3 Cells; Animals; Cell Transformation, Neoplastic; Methylcholanthrene; Mice; Mice, Inbred BALB C; Phosphorylation; Tetradecanoylphorbol Acetate; Tyrosine | 1994 |
Human GMP synthetase. Protein purification, cloning, and functional expression of cDNA.
Topics: Amino Acid Sequence; Base Sequence; Carbon-Nitrogen Ligases; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cloning, Molecular; DNA Primers; DNA, Complementary; Gene Expression; Genetic Complementation Test; Humans; Ligases; Molecular Sequence Data; RNA, Messenger; Sequence Alignment; Sequence Homology, Amino Acid; Tetradecanoylphorbol Acetate | 1994 |
Malignant transformation of human bronchial epithelial cells by radon-simulated alpha-particles.
Topics: Animals; Base Sequence; Bronchi; Cell Line, Transformed; Cell Transformation, Neoplastic; Genes, ras; Humans; Mice; Mice, Nude; Molecular Sequence Data; Mutation; Polymerase Chain Reaction; Radiation Dosage; Radon Daughters; Tetradecanoylphorbol Acetate | 1994 |
Selective nature of phorbol 12-myristate 13-acetate-induced neoplastic transformation in NIH 3T3 cells.
Topics: 3T3 Cells; Animals; Cell Division; Cell Transformation, Neoplastic; Culture Media; Mice; Phenotype; Tetradecanoylphorbol Acetate | 1994 |
Differential transformation efficiency but not AP-1 induction under anchorage-dependent and -independent conditions.
Topics: Animals; Cell Adhesion; Cell Transformation, Neoplastic; Cells, Cultured; Culture Media; DNA-Binding Proteins; Homeodomain Proteins; Mice; Minor Histocompatibility Antigens; Models, Biological; Proto-Oncogene Proteins c-bcl-2; Replication Protein C; Repressor Proteins; Saccharomyces cerevisiae Proteins; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1994 |
Inversion of carcinogen-promoter sequence: effects on mouse skin tumorigenesis and cellular growth kinetics.
Topics: Animals; Cell Division; Cell Transformation, Neoplastic; Disease Models, Animal; Female; Humans; Hyperplasia; Methylcholanthrene; Mice; Mice, Inbred Strains; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1993 |
A functional Ets DNA-binding domain is required to maintain multipotency of hematopoietic progenitors transformed by Myb-Ets.
Topics: Binding Sites; Cell Differentiation; Cell Transformation, Neoplastic; DNA; Gene Expression Regulation; Hematopoietic Stem Cells; Leukemia, Myelomonocytic, Acute; Mutation; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myb; Recombinant Fusion Proteins; Retroviridae Proteins, Oncogenic; Temperature; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Blocking of tumor promoter-induced AP-1 activity inhibits induced transformation in JB6 mouse epidermal cells.
Topics: Animals; Base Sequence; Binding Sites; Cell Line; Cell Transformation, Neoplastic; DNA; Epidermal Growth Factor; Fluocinolone Acetonide; Gene Expression; Genes, fos; Genes, jun; Genes, Reporter; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Point Mutation; Proto-Oncogene Proteins c-jun; Skin; Tetradecanoylphorbol Acetate; Transfection; Tretinoin | 1994 |
c-Myb prevents TPA-induced differentiation and cell death in v-Myb transformed monoblasts.
Topics: Animals; Cell Cycle; Cell Death; Cell Differentiation; Cell Transformation, Neoplastic; Chickens; Oncogenes; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myb; Proto-Oncogenes; Tetradecanoylphorbol Acetate | 1994 |
Sphingolipids inhibit multistage carcinogenesis and protein kinase C.
Topics: Animals; Anticarcinogenic Agents; Carcinogenicity Tests; Cell Line; Cell Transformation, Neoplastic; Gamma Rays; Mice; Mice, Inbred C3H; Protein Kinase C; Sphingolipids; Sphingosine; Tetradecanoylphorbol Acetate | 1993 |
Growth inhibition of human melanoma-derived cells by 12-O-tetradecanoyl phorbol 13-acetate.
Topics: Cell Division; Cell Transformation, Neoplastic; Down-Regulation; Humans; Isoenzymes; Melanoma; Protein Kinase C; Sensitivity and Specificity; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Protein kinase C alpha activates RAF-1 by direct phosphorylation.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Cell Line; Cell Transformation, Neoplastic; Cloning, Molecular; Enzyme Activation; Escherichia coli; Mice; Molecular Sequence Data; Moths; Mutation; Peptides; Protein Kinase C; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Rats; Recombinant Proteins; Serine; Tetradecanoylphorbol Acetate | 1993 |
The epsilon isoform of protein kinase C is an oncogene when overexpressed in rat fibroblasts.
Topics: Animals; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Down-Regulation; Fibroblasts; Isoenzymes; Oncogenes; Phenotype; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate | 1993 |
Differential signal requirement for upregulation of HLA-class II molecules in human lymphoma B cells.
Topics: Antibodies; Calcimycin; Cell Transformation, Neoplastic; Gene Expression Regulation, Neoplastic; Histocompatibility Antigens Class II; Humans; Immunoglobulin M; Interleukin-4; Lymphoma, B-Cell; Protein Kinase C; Receptors, Fc; Receptors, IgE; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Up-Regulation | 1993 |
Antipromoting effects of 5-lipoxygenase inhibitors, 3-nitro-2,4,6- trihydroxybenzamide derivatives, on TPA-promoted transformation in BALB 3T3 cells.
Topics: 3T3 Cells; Animals; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Hydroxamic Acids; Lipoxygenase Inhibitors; Methylcholanthrene; Mice; Tetradecanoylphorbol Acetate | 1993 |
Interaction of HPV-18 and nitrosomethylurea in the induction of squamous cell carcinoma.
Topics: Animals; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cocarcinogenesis; DNA, Viral; Humans; Keratinocytes; Methylnitrosourea; Mice; Mice, Inbred BALB C; Mice, Nude; Papillomaviridae; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Effect of glucocorticoids on TPA-induced inhibition of gap-junctional communication and morphological transformation in Syrian hamster embryo cells.
Topics: Animals; Cell Communication; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Embryo, Mammalian; Gap Junctions; Glucocorticoids; Tetradecanoylphorbol Acetate | 1993 |
Immortalization of Syrian hamster embryo cells: probabilistic event or deterministic process.
Topics: Animals; Benzo(a)pyrene; Cell Count; Cell Cycle; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Cellular Senescence; Cricetinae; Culture Techniques; Embryo, Mammalian; Kinetics; Mesocricetus; Models, Biological; Tetradecanoylphorbol Acetate; Time Factors | 1993 |
Conditional transformation of cells and rapid activation of the mitogen-activated protein kinase cascade by an estradiol-dependent human raf-1 protein kinase.
Topics: 3T3 Cells; Animals; Base Sequence; Cell Transformation, Neoplastic; Cloning, Molecular; DNA; Enzyme Activation; Estradiol; Ethers, Cyclic; Humans; Kinetics; Mice; Mitogen-Activated Protein Kinase 1; Molecular Sequence Data; Okadaic Acid; Phosphorylation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Rats; Receptors, Estrogen; Retroviridae; Signal Transduction; Tetradecanoylphorbol Acetate | 1993 |
Raf revertant cells resist transformation by non-nuclear oncogenes and are deficient in the induction of early response genes by TPA and serum.
Topics: 3T3 Cells; Animals; Blood Physiological Phenomena; Cell Transformation, Neoplastic; Gene Expression; Genes, fos; Mice; Oncogene Proteins v-raf; Oncogenes; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-fos; Retroviridae Proteins, Oncogenic; Tetradecanoylphorbol Acetate | 1993 |
Two phorbol ester receptor affinities in partially transformed human urothelial cells and decrease of receptor binding in desensitized cells.
Topics: Caenorhabditis elegans Proteins; Carrier Proteins; Cell Line, Transformed; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Humans; Phorbol 12,13-Dibutyrate; Protein Kinase C; Receptors, Drug; Tetradecanoylphorbol Acetate; Urinary Bladder; Urinary Bladder Neoplasms | 1993 |
Intercellular communication in colonies of Syrian hamster embryo cells and the susceptibility for morphological transformation.
Topics: Animals; Cell Communication; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Dieldrin; Diethylhexyl Phthalate; Down-Regulation; Embryo, Mammalian; Intercellular Junctions; Mesocricetus; Tetradecanoylphorbol Acetate; Vanadates | 1993 |
Differentiation-stage specific self-peptides bound by major histocompatibility complex class I molecules.
Topics: Amino Acid Sequence; Cell Differentiation; Cell Transformation, Neoplastic; Chromatography, High Pressure Liquid; Flow Cytometry; Fluorescent Antibody Technique; Histocompatibility Antigens Class I; Humans; Leukemia, Myeloid; Major Histocompatibility Complex; Molecular Sequence Data; Peptides; Phenotype; Precipitin Tests; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
An immediate early human gene encodes an Id-like helix-loop-helix protein and is regulated by protein kinase C activation in diverse cell types.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Base Sequence; Cell Transformation, Neoplastic; DNA-Binding Proteins; Enzyme Activation; Gene Expression Regulation; Genome, Human; Humans; Immunoglobulin Idiotypes; Inhibitor of Differentiation Proteins; Mice; Molecular Sequence Data; Protein Kinase C; Proteins; Sequence Homology, Amino Acid; Tetradecanoylphorbol Acetate; Transcription Factors | 1993 |
Severely decreased MARCKS expression correlates with ras reversion but not with mitogenic responsiveness.
Topics: 3T3 Cells; Animals; Cell Transformation, Neoplastic; Cells, Cultured; DNA; Genes, ras; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Mice; Myristoylated Alanine-Rich C Kinase Substrate; Phenotype; Phosphorylation; Protein Kinase C; Proteins; Tetradecanoylphorbol Acetate; Transfection | 1993 |
Overexpression of protein kinase C-delta and -epsilon in NIH 3T3 cells induces opposite effects on growth, morphology, anchorage dependence, and tumorigenicity.
Topics: 3T3 Cells; Animals; Biological Transport; Blotting, Northern; Blotting, Western; Brain; Cell Adhesion; Cell Division; Cell Transformation, Neoplastic; Cloning, Molecular; Enzyme Activation; Enzyme Stability; Indoles; Isoenzymes; Kinetics; Maleimides; Mice; Mice, Inbred C57BL; Mice, Nude; Neoplasms, Experimental; Protein Kinase C; Tetradecanoylphorbol Acetate | 1993 |
Suppression of oncogene-induced transformation by a deletion mutant of c-jun.
Topics: Animals; Base Sequence; Binding, Competitive; Cell Transformation, Neoplastic; Cells, Cultured; DNA Mutational Analysis; DNA-Binding Proteins; Genes, Dominant; Genes, ras; Genes, Suppressor; Humans; In Vitro Techniques; Molecular Sequence Data; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats; Sequence Deletion; Tetradecanoylphorbol Acetate; Transcriptional Activation | 1993 |
Differential effects of TPA and pristane on gene expression and transformation in mouse epidermal cells.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Epidermal Cells; Gene Expression; In Vitro Techniques; Mice; Promoter Regions, Genetic; Regulatory Sequences, Nucleic Acid; Terpenes; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1993 |
1 alpha,25-Dihydroxyvitamin D3 enhances 12-O-tetradecanoylphorbol-13-acetate- induced tumorigenic transformation and osteopontin expression in mouse JB6 epidermal cells.
Topics: Animals; Calcitriol; Cell Adhesion; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Cocarcinogenesis; Drug Synergism; Gene Expression; Mice; Osteopontin; Phosphorylation; RNA, Messenger; Sialoglycoproteins; Skin; Skin Neoplasms; Skin Physiological Phenomena; Tetradecanoylphorbol Acetate | 1993 |
Alterations in a voltage-gated K+ current during the differentiation of ML-1 human myeloblastic leukemia cells.
Topics: 4-Aminopyridine; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Humans; Ion Channel Gating; Leukemia, Myeloid, Acute; Membrane Potentials; Potassium Channels; Tetradecanoylphorbol Acetate; Tetraethylammonium Compounds; Tumor Cells, Cultured | 1993 |
60 Hz magnetic field acts as co-promoter in focus formation of C3H/10T1/2 cells.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Fibroblasts; Magnetics; Mice; Mice, Inbred C3H; Tetradecanoylphorbol Acetate; Video Recording | 1993 |
Regulation of Myc and Mad during epidermal differentiation and HPV-associated tumorigenesis.
Topics: Animals; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Cell Differentiation; Cell Transformation, Neoplastic; Cells, Cultured; DNA-Binding Proteins; Humans; Keratinocytes; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Transgenic; Papillomaviridae; Proto-Oncogene Proteins c-myc; Repressor Proteins; Tetradecanoylphorbol Acetate | 1995 |
A novel function of CD40: induction of cell death in transformed cells.
Topics: Animals; Antibodies; Apoptosis; CD40 Antigens; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Dose-Response Relationship, Drug; Drug Synergism; Epithelial Cells; Epithelium; fas Receptor; Growth Inhibitors; Humans; Interleukin-1; Mesoderm; Mice; Receptors, Tumor Necrosis Factor; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1996 |
Comparison of propylene oxide and epichlorohydrin effects in two transformation tests (C3H/10T1/2 and SHE cells).
Topics: Animals; Carcinogens; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Epichlorohydrin; Epoxy Compounds; Female; Mice; Mice, Inbred C3H; Mutagenicity Tests; Pregnancy; Tetradecanoylphorbol Acetate | 1995 |
Inhibition of tumor promoter-induced transformation by retinoids that transrepress AP-1 without transactivating retinoic acid response element.
Topics: Animals; Anticarcinogenic Agents; Base Sequence; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Gene Expression; Genes, Reporter; Luciferases; Mice; Molecular Sequence Data; Promoter Regions, Genetic; Regulatory Sequences, Nucleic Acid; Retinoids; Sensitivity and Specificity; Skin; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcriptional Activation; Transfection; Tretinoin | 1996 |
Sphingosine and its methylated derivative N,N-dimethylsphingosine (DMS) induce apoptosis in a variety of human cancer cell lines.
Topics: Animals; Apoptosis; Cell Line; Cell Line, Transformed; Cell Transformation, Neoplastic; Cells, Cultured; Colonic Neoplasms; DNA, Neoplasm; Endothelium, Vascular; Flow Cytometry; Glomerular Mesangium; HL-60 Cells; Humans; Kinetics; Rats; Sphingosine; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Umbilical Veins | 1996 |
Enhancement of BALB/c 3T3 cells transformation by 1,2-dibromoethane promoting effect.
Topics: 3T3 Cells; Animals; Carcinogens; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Ethane; Ethylene Dibromide; Hydrocarbons, Chlorinated; Methylnitronitrosoguanidine; Mice; Tetradecanoylphorbol Acetate | 1996 |
Carcinogenesis in human skin grafted to SCID mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Neoplasm; Carcinogens; Cell Differentiation; Cell Division; Cell Transformation, Neoplastic; Humans; Keratins; Ki-67 Antigen; Mice; Mice, SCID; Neoplasm Proteins; Nuclear Proteins; Papilloma; Skin Neoplasms; Skin Transplantation; Tetradecanoylphorbol Acetate; Transplantation, Heterologous; Ultraviolet Rays | 1996 |
Overexpression of protein kinase C epsilon is oncogenic in rat colonic epithelial cells.
Topics: Animals; Blotting, Western; Cell Adhesion; Cell Division; Cell Line; Cell Transformation, Neoplastic; Colon; Colonic Neoplasms; Epithelial Cells; Epithelium; Gene Expression; Genes, ras; Isoenzymes; Mice; Mice, Nude; Protein Kinase C; Rats; Recombinant Proteins; Tetradecanoylphorbol Acetate; Transfection; Transplantation, Heterologous | 1996 |
Radiation-induced neoplastic transformation of stationary phase C3H/10T1/2 cells in response to different dose rates and to post-irradiation treatment with tumor promoter.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Embryo, Mammalian; Fibroblasts; Mice; Tetradecanoylphorbol Acetate | 1996 |
Antioxidants inhibit the enhancement of malignant cell transformation induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Anticarcinogenic Agents; Antioxidants; Ascorbic Acid; Carcinogens; Cell Transformation, Neoplastic; Drug Interactions; Enzyme Inhibitors; Fibroblasts; Isoquinolines; Mannitol; Methylnitronitrosoguanidine; Mice; Mice, Inbred C3H; Piperazines; Polychlorinated Dibenzodioxins; Protein Kinase C; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Vitamin E | 1996 |
Drug-induced reversion of progression phenotype is accompanied by reversion of AP-1 phenotype in JB6 cells.
Topics: 3T3 Cells; Animals; Cell Division; Cell Line; Cell Transformation, Neoplastic; Clone Cells; Colforsin; Epidermal Growth Factor; Fluocinolone Acetonide; Glucocorticoids; Mice; Phenotype; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transfection | 1996 |
Studies on the mechanisms of tumorigenesis induced by polyetherurethanes in rats: leachable and biodegradable oligomers involving the diphenyl carbamate structure acted as an initiator on the transformation of Balb 3T3 cells.
Topics: 3T3 Cells; Animals; Biocompatible Materials; Butylated Hydroxytoluene; Carbamates; Carcinogens; Cell Transformation, Neoplastic; Colony-Forming Units Assay; Methanol; Mice; Mice, Inbred BALB C; Polyurethanes; Tetradecanoylphorbol Acetate | 1996 |
Chronic exposure of LLC-PK1 epithelia to the phorbol ester TPA produces polyp-like foci with leaky tight junctions and altered protein kinase C-alpha expression and localization.
Topics: Animals; Carcinoma; Cell Membrane; Cell Membrane Permeability; Cell Transformation, Neoplastic; Clone Cells; Coloring Agents; Cytosol; Electric Impedance; Epithelial Cells; Epithelium; Isoenzymes; LLC-PK1 Cells; Mannitol; Protein Kinase C; Protein Kinase C-alpha; Ruthenium Red; Swine; Tetradecanoylphorbol Acetate; Tight Junctions | 1996 |
Paradoxical tumor inhibitory effect of p53 loss in transgenic mice expressing epidermal-targeted v-rasHa, v-fos, or human transforming growth factor alpha.
Topics: Animals; Animals, Newborn; Cell Differentiation; Cell Division; Cell Transformation, Neoplastic; Cocarcinogenesis; Crosses, Genetic; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Epidermis; Genes, fos; Genes, p53; Genes, ras; Hyperplasia; Keratinocytes; Mice; Mice, Knockout; Mice, Transgenic; Oncogene Protein p21(ras); Oncogene Proteins v-fos; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha; Transgenes | 1996 |
pH effects on the lifespan and transformation frequency of Syrian hamster embryo (SHE) cells.
Topics: Animals; Benzo(a)pyrene; Carcinogens; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; Cellular Senescence; Cricetinae; Embryo, Mammalian; Hydrogen-Ion Concentration; Mesocricetus; Nickel; Tetradecanoylphorbol Acetate; Time Factors; X-Rays | 1996 |
Protection against malignant conversion in SENCAR mouse skin by all trans retinoic acid: inhibition of the ras p21-processing enzyme farnesyltransferase and Ha-ras p21 membrane localization.
Topics: Alkyl and Aryl Transferases; Animals; Carcinoma; Cell Compartmentation; Cell Membrane; Cell Transformation, Neoplastic; Cytosol; Diterpenes; Enzyme Inhibitors; Mice; Papilloma; Proto-Oncogene Proteins p21(ras); Skin; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate; Transferases; Tretinoin | 1996 |
Up-regulation of vascular endothelial growth factor/vascular permeability factor in mouse skin carcinogenesis correlates with malignant progression state and activated H-ras expression levels.
Topics: Animals; Carcinoma, Squamous Cell; Cell Line, Transformed; Cell Transformation, Neoplastic; Disease Progression; Endothelial Growth Factors; Female; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Genes, ras; Interleukin 1 Receptor Antagonist Protein; Keratinocytes; Lymphokines; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred SENCAR; Neoplasm Metastasis; Neoplasm Proteins; Neovascularization, Pathologic; Oncogene Protein p21(ras); Papilloma; Precancerous Conditions; Proto-Oncogene Proteins p21(ras); RNA, Messenger; RNA, Neoplasm; Sialoglycoproteins; Skin Neoplasms; Species Specificity; Tetradecanoylphorbol Acetate; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1996 |
PKC epsilon functions as an oncogene by enhancing activation of the Raf kinase.
Topics: Animals; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Colony-Forming Units Assay; Enzyme Activation; Fibroblasts; Genes, ras; Genetic Vectors; Isoenzymes; Oncogenes; Protein Kinase C; Protein Kinase C-epsilon; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Rats; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection | 1996 |
Asbestos promotes morphological transformation and elevates expression of a gene family invariably induced by tumor promoters in C3H/10T1/2 cells.
Topics: Animals; Antioxidants; Asbestos; Asbestos, Crocidolite; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Gene Expression Regulation; Glycoproteins; Intercellular Signaling Peptides and Proteins; Mice; Mice, Inbred C3H; Prolactin; RNA, Messenger; Tetradecanoylphorbol Acetate | 1996 |
Phosphatidylinositol-3 kinase is necessary for 12-O-tetradecanoylphorbol-13-acetate-induced cell transformation and activated protein 1 activation.
Topics: Androstadienes; Animals; Cell Line; Cell Transformation, Neoplastic; Chromones; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Epidermal Cells; Epidermis; Insulin; Mice; Morpholines; Phosphatidylinositol 3-Kinases; Phosphotransferases (Alcohol Group Acceptor); Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Wortmannin | 1997 |
Manganese superoxide dismutase expression inhibits soft agar growth in JB6 clone41 mouse epidermal cells.
Topics: Animals; Carcinogens; Cell Line, Transformed; Cell Transformation, Neoplastic; Disease Susceptibility; Enzyme Induction; Epidermal Cells; Gene Expression Regulation; Genes, fos; Genes, jun; Humans; Mice; Oxidative Stress; Recombinant Fusion Proteins; Signal Transduction; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transfection | 1997 |
Inhibition of activator protein 1 activity and neoplastic transformation by aspirin.
Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Aspirin; Calcium-Calmodulin-Dependent Protein Kinases; Carcinogens; Cell Adhesion; Cell Transformation, Neoplastic; Cyclooxygenase Inhibitors; Diethylstilbestrol; Genes, jun; Genes, ras; Hydrogen-Ion Concentration; Indomethacin; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphorylation; Sodium Salicylate; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Tumor Cells, Cultured | 1997 |
Focus formation of C3H/10T1/2 cells and exposure to a 836.55 MHz modulated radiofrequency field.
Topics: Analysis of Variance; Animals; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Coculture Techniques; Dose-Response Relationship, Drug; Electromagnetic Fields; Fibroblasts; Mice; Mice, Inbred C3H; Microscopy, Video; Radio Waves; Tetradecanoylphorbol Acetate | 1997 |
Differentiating agents modulate topoisomerase I activity in U-937 promonocytic cells.
Topics: Acetamides; Antineoplastic Agents; Blotting, Northern; Blotting, Western; Carcinogens; Cell Transformation, Neoplastic; DNA Topoisomerases, Type I; Electrophoresis, Polyacrylamide Gel; Humans; Leukemia, Myeloid; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tretinoin; Tumor Cells, Cultured | 1997 |
Tumor promotion by depleting cells of protein kinase C delta.
Topics: Animals; Antineoplastic Agents; Bryostatins; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Down-Regulation; Fibroblasts; Isoenzymes; Lactones; Macrolides; Phenotype; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-delta; Protein Kinase C-epsilon; Proto-Oncogene Proteins pp60(c-src); Rats; Tetradecanoylphorbol Acetate; Transfection | 1997 |
Expression of an Epstein-Barr-virus receptor and Epstein-Barr-virus-dependent transformation of human nasopharyngeal epithelial cells.
Topics: Base Sequence; Binding Sites; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; DNA; DNA, Viral; Embryo, Mammalian; Epithelium; Gene Expression; Herpesvirus 4, Human; Humans; Molecular Sequence Data; Nasopharyngeal Neoplasms; Nasopharynx; Polymerase Chain Reaction; Receptors, Complement 3d; Receptors, Virus; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1997 |
Grafting assay distinguishes promotion sensitive from promotion resistant JB6 cells.
Topics: Animals; Carcinogens; Cell Line, Transformed; Cell Transformation, Neoplastic; Disease Models, Animal; Fibroblasts; Male; Mice; Mice, Inbred BALB C; Mice, Inbred SENCAR; Mice, Nude; Mutation; Neoplasm Transplantation; Phenotype; Sensitivity and Specificity; Skin; Skin Neoplasms; Skin Physiological Phenomena; Tetradecanoylphorbol Acetate; Transcription Factor AP-1 | 1997 |
IkappaB alpha is a target for the mitogen-activated 90 kDa ribosomal S6 kinase.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Transformation, Neoplastic; Cell Transformation, Viral; COS Cells; DNA-Binding Proteins; Humans; I-kappa B Proteins; Mitogens; Mutation; NF-kappa B; NF-kappa B p50 Subunit; NF-KappaB Inhibitor alpha; Phosphorylation; Precipitin Tests; Protein Binding; Protein Precursors; Protein Serine-Threonine Kinases; Ribosomal Protein S6 Kinases; Serine; Signal Transduction; Substrate Specificity; Tetradecanoylphorbol Acetate | 1997 |
Inositol hexaphosphate inhibits cell transformation and activator protein 1 activation by targeting phosphatidylinositol-3' kinase.
Topics: Animals; Anticarcinogenic Agents; Cell Line; Cell Transformation, Neoplastic; Epidermal Growth Factor; Mice; Phosphatidylinositol 3-Kinases; Phosphotransferases (Alcohol Group Acceptor); Phytic Acid; Tetradecanoylphorbol Acetate; Transcription Factor AP-1 | 1997 |
Power frequency magnetic fields do not contribute to transformation of JB6 cells.
Topics: Animals; Blood Physiological Phenomena; Cell Transformation, Neoplastic; Cells, Cultured; Dose-Response Relationship, Drug; Magnetics; Mice; Tetradecanoylphorbol Acetate | 1997 |
A dominant negative mutant of jun blocking 12-O-tetradecanoylphorbol-13-acetate-induced invasion in mouse keratinocytes.
Topics: Animals; Anticarcinogenic Agents; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Glycoproteins; Keratinocytes; Matrix Metalloproteinases, Membrane-Associated; Metalloendopeptidases; Mice; Mutation; NF-kappa B; Proto-Oncogene Proteins c-jun; RNA, Messenger; Tetradecanoylphorbol Acetate; Tissue Inhibitor of Metalloproteinases; Transcription Factor AP-1; Transcriptional Activation; Transfection; Tumor Suppressor Protein p53 | 1997 |
Inhibitory effects of shouseiryu-to on two-stage carcinogenesis. II. Anti-tumor-promoting activities of lignans from Asiasarum heterotropoides var. mandshuricum.
Topics: Animals; Anticarcinogenic Agents; Antigens, Viral; Cell Line; Cell Transformation, Neoplastic; Dioxoles; Female; Furans; Lignans; Lung Neoplasms; Mice; Mice, Inbred ICR; Phenols; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1997 |
VEGF mRNA is stabilized by ras and tyrosine kinase oncogenes, as well as by UV radiation--evidence for divergent stabilization pathways.
Topics: 3T3 Cells; Acetylcysteine; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Hypoxia; Cell Transformation, Neoplastic; DNA-Binding Proteins; Endothelial Growth Factors; Genes, ras; Genistein; Humans; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Isoflavones; Lymphokines; Mice; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Nuclear Proteins; Phosphorylation; Protein-Tyrosine Kinases; ras Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription Factors; Tumor Cells, Cultured; Ultraviolet Rays; Up-Regulation; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1997 |
Inhibitors of both nuclear factor-kappaB and activator protein-1 activation block the neoplastic transformation response.
Topics: Animals; Anticarcinogenic Agents; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; DNA; Genes, Reporter; Mice; NF-kappa B; Pyrrolidines; Retinoids; Tetradecanoylphorbol Acetate; Thiocarbamates; Time Factors; Transcription Factor AP-1; Transcriptional Activation; Transfection; Tumor Necrosis Factor-alpha | 1997 |
Inhibitory effects of phytopolyphenols on TPA-induced transformation, PKC activation, and c-jun expression in mouse fibroblast cells.
Topics: 3T3 Cells; Animals; Carcinogens; Catechin; Cell Line; Cell Transformation, Neoplastic; Curcumin; Down-Regulation; Fibroblasts; Flavonoids; Flavonols; Gene Expression Regulation, Neoplastic; Genes, jun; Mice; Phenols; Polymers; Protein Kinase C; Tetradecanoylphorbol Acetate | 1997 |
Epstein-Barr virus in synergy with tumor-promoter-induced malignant transformation of immortalized human epithelial cells.
Topics: Animals; Carcinogens; Cell Division; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Cocarcinogenesis; DNA, Viral; Epithelium; Female; Herpesvirus 4, Human; Humans; Kidney; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Receptors, Complement 3d; Receptors, Virus; Tetradecanoylphorbol Acetate | 1997 |
Differential activation of keratinocyte phospholipase A2S by tumor promoters and other irritants.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Cytosol; Eicosanoids; Enzyme Activation; Enzyme Inhibitors; Epidermal Cells; Fatty Acids; Isoenzymes; Keratinocytes; Membrane Lipids; Mice; Naphthalenes; Oligonucleotides, Antisense; Papilloma; Phosphatidylcholines; Phospholipases A; Phospholipids; Pyrones; Recombinant Fusion Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1997 |
Inhibition of tumor promoter-induced activator protein 1 activation and cell transformation by tea polyphenols, (-)-epigallocatechin gallate, and theaflavins.
Topics: Animals; Anticarcinogenic Agents; Biflavonoids; Catechin; Cell Transformation, Neoplastic; Chemoprevention; Epidermal Growth Factor; Mice; Phosphorylation; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-jun; Signal Transduction; Tea; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcriptional Activation | 1997 |
Relationship between exposure to TPA and appearance of transformed cells in MNNG-initiated transformation of BALB/c 3T3 cells.
Topics: 3T3 Cells; Animals; Carcinogens; Cell Count; Cell Line, Transformed; Cell Transformation, Neoplastic; Methylnitronitrosoguanidine; Mice; Mice, Inbred BALB C; Tetradecanoylphorbol Acetate; Time Factors | 1997 |
Calcitriol enhancement of TPA-induced tumorigenic transformation is mediated through vitamin D receptor-dependent and -independent pathways.
Topics: 25-Hydroxyvitamin D3 1-alpha-Hydroxylase; Animals; Calcitriol; Cell Division; Cell Line; Cell Transformation, Neoplastic; Epidermal Cells; Mice; Osteopontin; Receptors, Calcitriol; Sialoglycoproteins; Tetradecanoylphorbol Acetate; Transfection; Vitamin D | 1997 |
bcl-2 enhancement of malignant transformation in mouse epidermal JB6 cells.
Topics: Animals; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Clone Cells; Cocarcinogenesis; Gene Expression; Genes, fos; Genes, jun; Mice; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; RNA, Messenger; Skin; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcriptional Activation; Transfection | 1997 |
Oncogenic transformation of Syrian hamster embryo cells by 5.3-MeV alpha particles and a tumor promoter phorbol ester.
Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Embryo, Mammalian; Mesocricetus; Plutonium; Tetradecanoylphorbol Acetate | 1996 |
Selenocompounds induce a redox modulation of protein kinase C in the cell, compartmentally independent from cytosolic glutathione: its role in inhibition of tumor promotion.
Topics: Animals; Anticarcinogenic Agents; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Chromatography, DEAE-Cellulose; Cystine; Cytosol; Glutathione; Glutathione Disulfide; Isoenzymes; Kinetics; Mice; Organoselenium Compounds; Oxidation-Reduction; Phorbol 12,13-Dibutyrate; Protein Kinase C; Sodium Selenite; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1997 |
Inhibition of tumor promoter activity toward mouse fibroblasts and their in vitro transformation by tissue inhibitor of metalloproteinases-1 (TIMP-1).
Topics: 3T3 Cells; Animals; Antineoplastic Agents; Cell Communication; Cell Transformation, Neoplastic; Fibroblasts; Gap Junctions; Metalloendopeptidases; Methylnitronitrosoguanidine; Mice; Protease Inhibitors; Tetradecanoylphorbol Acetate; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2 | 1997 |
Signal transduction in fibroblasts stably transformed by [Val12]Ras--the activities of extracellular-signal-regulated kinase and Jun N-terminal kinase are only moderately increased, and the activity of the delta-inhibitor of c-Jun is not alleviated.
Topics: Animals; Benzodiazepines; Blotting, Northern; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line, Transformed; Cell Transformation, Neoplastic; Genes, ras; Histones; Humans; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases; Myelin Basic Protein; Proto-Oncogene Proteins c-jun; Rats; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factors; Transcriptional Activation; Tumor Cells, Cultured | 1997 |
Shortage of mitogen-activated protein kinase is responsible for resistance to AP-1 transactivation and transformation in mouse JB6 cells.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Epidermal Growth Factor; Epidermis; Mice; Phosphorylation; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcriptional Activation | 1998 |
Colon carcinoma cells use different mechanisms to escape CD95-mediated apoptosis.
Topics: Antigens, Neoplasm; Apoptosis; Brefeldin A; Carcinoma; Cell Transformation, Neoplastic; Colonic Neoplasms; Cycloheximide; Cyclopentanes; Dactinomycin; Enzyme Inhibitors; Fas Ligand Protein; fas Receptor; Humans; Immunologic Capping; Interferon-gamma; Intestinal Mucosa; Membrane Glycoproteins; Nucleic Acid Synthesis Inhibitors; Phorbol Esters; Protein Kinase C; Protein Synthesis Inhibitors; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1998 |
The catalytic domain of PKC-epsilon, in reciprocal PKC-delta and -epsilon chimeras, is responsible for conferring tumorgenicity to NIH3T3 cells, whereas both regulatory and catalytic domains of PKC-epsilon contribute to in vitro transformation.
Topics: 3T3 Cells; Animals; Catalysis; Cell Division; Cell Transformation, Neoplastic; Isoenzymes; Mice; Mice, Nude; Protein Kinase C; Protein Kinase C-delta; Protein Kinase C-epsilon; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate | 1998 |
Two-stage exposure of Syrian-hamster-embryo cells to environmental carcinogens: superinduction of ornithine decarboxylase correlates with increase of morphological-transformation frequency.
Topics: Animals; Benzo(a)pyrene; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Clofibrate; Cricetinae; Drug Administration Schedule; Enzyme Induction; Mesocricetus; Ornithine Decarboxylase; Tetradecanoylphorbol Acetate | 1998 |
Phorbol 12-myristate 13-acetate can transform monocyte-derived dendritic cells to different cell types similar to those found in dermatofibroma. A possible in vitro model of the histogenesis of dermatofibroma.
Topics: Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Cytokines; Dendritic Cells; Flow Cytometry; Histiocytoma, Benign Fibrous; Humans; Immunohistochemistry; Leukocytes, Mononuclear; Lipopolysaccharide Receptors; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1998 |
Topical retinoic acid reduces skin papilloma formation but resistant papillomas are at high risk for malignant conversion.
Topics: Administration, Topical; Animals; Anticarcinogenic Agents; Antineoplastic Agents; Biomarkers, Tumor; Carcinogens; Carcinoma, Basal Cell; Cell Transformation, Neoplastic; Disease Progression; Diterpenes; Female; Immunohistochemistry; Mice; Mice, Inbred BALB C; Mice, Inbred SENCAR; Papilloma; Phenotype; Precancerous Conditions; Receptors, Retinoic Acid; Retinoid X Receptors; Risk Factors; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate; Transcription Factors; Transforming Growth Factor beta; Tretinoin | 1998 |
Overexpression of PKCepsilon in R6 fibroblasts causes increased production of active TGFbeta.
Topics: Animals; Cell Adhesion; Cell Division; Cell Line; Cell Transformation, Neoplastic; Culture Media, Conditioned; DNA; Fibroblasts; Isoenzymes; Mitogens; Molecular Weight; Protein Kinase C; Protein Kinase C-epsilon; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta | 1998 |
Phase transitions in the growth of C3H 10T1/2 cells.
Topics: Animals; Anticarcinogenic Agents; Carcinogens; Cell Cycle Proteins; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclins; Dose-Response Relationship, Radiation; Linear Energy Transfer; Mice; Mice, Inbred C3H; Microtubule-Associated Proteins; RNA, Messenger; S Phase; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Suppressor Proteins | 1998 |
[Spontaneous reversion of tumor cells as a source of dormant metastases].
Topics: Animals; Carcinogens; Cell Division; Cell Transformation, Neoplastic; Culture Media; Growth Substances; Mice; Neoplasm Metastasis; Proto-Oncogene Proteins c-jun; Sarcoma, Experimental; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1998 |
Migration induction of contact inhibited C3H 10T1/2 cells by protein kinase C (PKC) dependent process.
Topics: Animals; Blotting, Western; Carcinogens; Cell Movement; Cell Transformation, Neoplastic; Collagen; Contact Inhibition; Diglycerides; Enzyme Activation; Fibronectins; Integrins; MAP Kinase Kinase Kinase 1; Mice; Mice, Inbred C3H; Polymerase Chain Reaction; Protein Kinase C; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Tetradecanoylphorbol Acetate | 1998 |
Tumor promoter induces high mobility group HMG-Y protein expression in transformation-sensitive but not -resistant cells.
Topics: Alternative Splicing; Animals; Carcinogens; Cell Transformation, Neoplastic; Gene Expression Regulation, Neoplastic; Genetic Variation; High Mobility Group Proteins; HMGA1a Protein; Mice; Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factors; Transcription, Genetic | 1998 |
Increased DNA synthesis in INIT/10T1/2 cells after exposure to a 60 Hz magnetic field: a magnetic-field or a thermal effect?
Topics: Animals; Carcinogens; Cell Division; Cell Transformation, Neoplastic; CHO Cells; Cricetinae; DNA; Electromagnetic Fields; Fibroblasts; Hot Temperature; Humans; Jurkat Cells; Methylcholanthrene; Mice; Mice, Inbred C3H; Proto-Oncogene Proteins c-myc; Tetradecanoylphorbol Acetate; Thymidine; Tritium | 1999 |
Expression of dominant negative Erk2 inhibits AP-1 transactivation and neoplastic transformation.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Epidermal Cells; Epidermal Growth Factor; Gene Expression Regulation, Neoplastic; Genes, Dominant; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Mutation; Phosphorylation; Recombinant Proteins; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcriptional Activation; Transfection | 1998 |
Effect of magnetic field exposure on anchorage-independent growth of a promoter-sensitive mouse epidermal cell line (JB6).
Topics: Analysis of Variance; Animals; Carcinogens; Cell Division; Cell Line, Transformed; Cell Transformation, Neoplastic; Clone Cells; Cocarcinogenesis; Dose-Response Relationship, Drug; Electromagnetic Fields; Epidermal Cells; Epidermis; Epithelial Cells; Mice; Neoplasms, Radiation-Induced; Single-Blind Method; Tetradecanoylphorbol Acetate | 1999 |
Protein kinase C expression links natural antibody binding with surveillance of activated and preneoplastic cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Binding Sites, Antibody; Cell Transformation, Neoplastic; Enzyme Activation; Enzyme Inhibitors; Fibroblasts; Genes, ras; Immunity, Innate; Isoenzymes; Male; Mice; Mice, Inbred C3H; Precancerous Conditions; Protein Kinase C; Protein Kinase C beta; Rats; Tetradecanoylphorbol Acetate; Tumor Stem Cell Assay | 1999 |
Apoptosis inhibition and ornithine decarboxylase superinduction as early epigenetic events in morphological transformation of Syrian hamster embryo cells exposed to 2-methoxyacetaldehyde, a metabolite of 2-methoxyethanol.
Topics: Acetaldehyde; Animals; Apoptosis; bcl-X Protein; Carcinogenicity Tests; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; DNA Fragmentation; Embryo, Mammalian; Enzyme Induction; Ethylene Glycols; Female; Mesocricetus; Ornithine Decarboxylase; Proto-Oncogene Proteins c-bcl-2; Teratogens; Tetradecanoylphorbol Acetate; Xenobiotics | 1999 |
TPA induces a block of differentiation and increases the susceptibility to neoplastic transformation of a rat thyroid epithelial cell line.
Topics: Animals; Antigens, Polyomavirus Transforming; Carcinogens; Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; Epithelial Cells; Genes, mos; Genes, ras; Genes, src; Iodide Peroxidase; Nuclear Proteins; Protein Kinase C; Rats; Rats, Inbred Strains; Receptors, Thyrotropin; Retroviridae; Tetradecanoylphorbol Acetate; Thyroglobulin; Thyroid Gland; Thyroid Nuclear Factor 1; Transcription Factors | 1998 |
Iodide symporter gene expression in normal and transformed rat thyroid cells.
Topics: Animals; Blotting, Northern; Carrier Proteins; Cell Transformation, Neoplastic; Colforsin; Cyclic AMP; Down-Regulation; Gene Expression Regulation; Insulin; Iodides; Iodine; Membrane Proteins; Rats; RNA, Messenger; Symporters; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin; Tumor Cells, Cultured; Up-Regulation | 1999 |
Posttranslational regulation of Myc function in response to phorbol ester/interferon-gamma-induced differentiation of v-Myc-transformed U-937 monoblasts.
Topics: Antineoplastic Agents; Carcinogens; Cell Differentiation; Cell Transformation, Neoplastic; Genes, myc; Humans; Interferon-gamma; Monocytes; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-myc; Tetradecanoylphorbol Acetate; U937 Cells | 1999 |
Involvement of protein kinase Cepsilon (PKCepsilon) in thyroid cell death. A truncated chimeric PKCepsilon cloned from a thyroid cancer cell line protects thyroid cells from apoptosis.
Topics: Amino Acid Sequence; Animals; Apoptosis; Base Sequence; Cell Transformation, Neoplastic; Chromosome Mapping; Chromosomes, Human, Pair 2; Cloning, Molecular; Humans; In Situ Hybridization, Fluorescence; Isoenzymes; Mice; Mice, Nude; Molecular Sequence Data; Protein Kinase C; Protein Kinase C-epsilon; Recombinant Proteins; Tetradecanoylphorbol Acetate; Thyroid Gland; Tumor Cells, Cultured | 1999 |
Transgenic mice demonstrate AP-1 (activator protein-1) transactivation is required for tumor promotion.
Topics: Animals; Cell Transformation, Neoplastic; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Transgenic; Promoter Regions, Genetic; Proto-Oncogene Proteins c-jun; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcriptional Activation | 1999 |
Effects of superoxide anion, B(alpha)P and TPA on the membrane fluidity of NIH3T3 cells.
Topics: 3T3 Cells; Animals; Benzo(a)pyrene; Carcinogens; Cell Transformation, Neoplastic; Free Radicals; Membrane Fluidity; Mice; Oxygen; Tetradecanoylphorbol Acetate | 1997 |
Tumor suppression by p27Kip1 and p21Cip1 during chemically induced skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoma; Animals; Carcinogens; Carcinoma; Cell Cycle Proteins; Cell Transformation, Neoplastic; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Cyclins; Genes, ras; Genes, Tumor Suppressor; Intestinal Neoplasms; Keratinocytes; Mice; Mice, Knockout; Microtubule-Associated Proteins; Mutation; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Suppressor Proteins | 1999 |
A multihit, multistage model of chemical carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cocarcinogenesis; DNA Mutational Analysis; DNA, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Genes, ras; Keratinocytes; Keratins; Mice; Models, Biological; Neoplasm Proteins; Papilloma; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; S Phase; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1999 |
JNK activation is required for JB6 cell transformation induced by tumor necrosis factor-alpha but not by 12-O-tetradecanoylphorbol-13-acetate.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Enzyme Activation; JNK Mitogen-Activated Protein Kinases; Mice; Mitogen-Activated Protein Kinases; Mutation; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1999 |
Antagonistic effects of protein kinase C alpha and delta on both transformation and phospholipase D activity mediated by the epidermal growth factor receptor.
Topics: Acetophenones; Animals; Benzopyrans; Carbazoles; Cell Transformation, Neoplastic; Cells, Cultured; Crosses, Genetic; Epidermal Growth Factor; ErbB Receptors; Indoles; Isoenzymes; Models, Genetic; Mutagenesis, Insertional; Phospholipase D; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-delta; Rats; Recombinant Proteins; Tetradecanoylphorbol Acetate | 1999 |
Tumor promoter-induced ornithine decarboxylase gene expression occurs independently of AP-1 activation.
Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Eflornithine; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Mice; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Proto-Oncogene Proteins c-jun; Tetradecanoylphorbol Acetate; Transcription Factor AP-1 | 1999 |
12-O-tetradecanoylphorbol-13-acetate promotion of transgenic mouse epidermis coexpressing transforming growth factor-alpha and v-fos: acceleration of autonomous papilloma formation and malignant conversion via c-Ha-ras activation.
Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Gene Expression Regulation, Neoplastic; Genes, fos; Genes, ras; Humans; Mice; Mice, Transgenic; Oncogene Proteins v-fos; Papilloma; Proto-Oncogene Proteins p21(ras); Skin Neoplasms; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha | 1999 |
Differentially expressed protein Pdcd4 inhibits tumor promoter-induced neoplastic transformation.
Topics: Animals; Apoptosis Regulatory Proteins; Cell Line; Cell Transformation, Neoplastic; Gene Expression; Humans; Immunoblotting; Keratinocytes; Mice; Mice, Inbred BALB C; Phenotype; Protein Biosynthesis; Proteins; Rabbits; RNA-Binding Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1999 |
Differential expression of the splicing regulatory factor genes during two-step chemical transformation in a BALB/3T3-derived cell line, MT-5.
Topics: 3T3 Cells; Animals; Base Sequence; Cell Line; Cell Transformation, Neoplastic; DNA Primers; Methylnitronitrosoguanidine; Mice; Mice, Inbred BALB C; Nuclear Proteins; RNA Splicing; RNA-Binding Proteins; Serine-Arginine Splicing Factors; Tetradecanoylphorbol Acetate | 1999 |
Induction of cyclooxygenase expression and enhancement of malignant cell transformation by 2,3,7,8-tetrachlorodibenzo-p-dioxin.
Topics: Animals; Arachidonic Acid; Cell Transformation, Neoplastic; Enzyme Induction; Fibroblasts; Mice; Mice, Inbred C3H; Polychlorinated Dibenzodioxins; Prostaglandin-Endoperoxide Synthases; Prostaglandins; RNA, Messenger; Tetradecanoylphorbol Acetate | 2000 |
Oncogenic potential of cyclin E in T-cell lymphomagenesis in transgenic mice: evidence for cooperation between cyclin E and Ras but not Myc.
Topics: Animals; Cell Transformation, Neoplastic; Cyclin E; Embryo, Mammalian; Fibroblasts; Genes, myc; Genes, ras; Hyperplasia; Ionomycin; Locus Control Region; Lymphoid Tissue; Lymphoma, T-Cell; Methylnitrosourea; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Transgenic; Point Mutation; Protamine Kinase; Rats; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymus Gland | 1999 |
Rap1-suppressed tumorigenesis is concomitant with the interference in ras effector signaling.
Topics: Animals; Cell Division; Cell Transformation, Neoplastic; Enzyme Activation; Epidermal Growth Factor; Humans; Insulin; Mice; Mice, Inbred BALB C; Mice, Nude; Mitogen-Activated Protein Kinases; Nerve Growth Factor; rap1 GTP-Binding Proteins; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 2000 |
Screening for the in vitro anti-tumor-promoting activities of edible plants from Malaysia.
Topics: Antineoplastic Agents; Cell Transformation, Neoplastic; Drug Screening Assays, Antitumor; Herpesvirus 4, Human; Malaysia; Plant Extracts; Plants, Edible; Plants, Medicinal; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2000 |
Enhancement of the transformed shape phenotype by microtubule inhibitors and reversal by an inhibitor combination.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Colchicine; Insulin; Microtubules; Monensin; Paclitaxel; Phenotype; Rats; Tetradecanoylphorbol Acetate; Valinomycin | 2000 |
The dominant negative Ras mutant, N17Ras, can inhibit signaling independently of blocking Ras activation.
Topics: Cell Transformation, Neoplastic; DNA-Binding Proteins; ets-Domain Protein Elk-1; Genes, ras; Growth Substances; Guanosine Diphosphate; Guanosine Triphosphate; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Mutation; Phosphorylation; Proto-Oncogene Proteins; ras Proteins; Ribosomal Protein S6 Kinases, 90-kDa; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factors; Transcriptional Activation | 2000 |
Differential abilities of the Raf family of protein kinases to abrogate cytokine dependency and prevent apoptosis in murine hematopoietic cells by a MEK1-dependent mechanism.
Topics: Animals; Apoptosis; Autocrine Communication; Cell Division; Cell Line; Cell Line, Transformed; Cell Transformation, Neoplastic; Dimethyl Sulfoxide; Enzyme Activation; Estradiol; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic Stem Cells; Interleukin-3; MAP Kinase Kinase 1; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Multigene Family; Phosphorylation; Protein Isoforms; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-raf; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Transfection | 2000 |
Effect of a tyrosine 155 to phenylalanine mutation of protein kinase cdelta on the proliferative and tumorigenic properties of NIH 3T3 fibroblasts.
Topics: 3T3 Cells; Animals; Base Sequence; Biological Transport; Cell Line; Cell Transformation, Neoplastic; DNA; Fibroblasts; Humans; Isoenzymes; Mice; Mutagenesis, Site-Directed; Phenylalanine; Protein Kinase C; Protein Kinase C-delta; Subcellular Fractions; Tetradecanoylphorbol Acetate; Tyrosine | 2000 |
Transforming JB6 cells exhibit enhanced integrin-mediated adhesion to osteopontin.
Topics: Animals; beta-N-Acetylhexosaminidases; Cell Adhesion; Cell Line; Cell Transformation, Neoplastic; Epidermis; Integrins; Kinetics; Mice; Osteopontin; Precancerous Conditions; Receptors, Cell Surface; Sialoglycoproteins; Tetradecanoylphorbol Acetate | 2000 |
Inhibitory effects of hydrolyzable tannins on tumor promoting activities induced by 12-O-tetradecanoyl-phorbol-13-acetate (TPA) in JB6 mouse epidermal cells.
Topics: Animals; Anticarcinogenic Agents; Cell Transformation, Neoplastic; Cells, Cultured; Hydrolysis; Mice; Mice, Inbred BALB C; Molecular Structure; Skin; Tannins; Tetradecanoylphorbol Acetate | 1999 |
ERK1/2 phosphorylation, induced by electromagnetic fields, diminishes during neoplastic transformation.
Topics: Animals; Blotting, Western; Cell Transformation, Neoplastic; Cells, Cultured; Diterpenes; DNA; Electromagnetic Fields; Electrophoresis, Agar Gel; Fibroblasts; HSP110 Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Phosphorylation; Proto-Oncogene Proteins c-fos; Retinyl Esters; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Vitamin A | 2000 |
Aberrant cell cycle progression contributes to the early-stage accelerated carcinogenesis in transgenic epidermis expressing the dominant negative TGFbetaRII.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bromodeoxyuridine; Carcinogens; Carcinoma, Squamous Cell; Carrier Proteins; Cell Cycle; Cell Cycle Proteins; Cell Transformation, Neoplastic; Centrosome; Cyclin-Dependent Kinase Inhibitor p15; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p27; Epidermal Cells; Gene Expression; Mice; Mice, Transgenic; Microtubule-Associated Proteins; Mitosis; Papilloma; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; Tetradecanoylphorbol Acetate; Time Factors; Tumor Suppressor Proteins | 2000 |
Constitutive expression of erbB2 in epidermis of transgenic mice results in epidermal hyperproliferation and spontaneous skin tumor development.
Topics: Animals; Carcinogens; Carcinoma, Squamous Cell; Cattle; Cell Differentiation; Cell Division; Cell Transformation, Neoplastic; Cocarcinogenesis; Dimerization; Disease Progression; Epidermis; ErbB Receptors; Female; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Genes, erbB-2; Genes, ras; Genes, Synthetic; Hyperplasia; Keratins; Male; Mice; Mice, Inbred ICR; Mice, Transgenic; Neoplasm Proteins; Papilloma; Phosphorylation; Promoter Regions, Genetic; Protein Processing, Post-Translational; Rats; Receptor, ErbB-2; Receptor, ErbB-3; Recombinant Fusion Proteins; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transgenes | 2000 |
Inhibition of 12-O-tetradecanoylphorbol-13-acetate-induced NF-kappaB activation by tea polyphenols, (-)-epigallocatechin gallate and theaflavins.
Topics: Animals; Anticarcinogenic Agents; Biflavonoids; Carcinogens; Catechin; Cell Line; Cell Transformation, Neoplastic; DNA; Epidermis; Flavonoids; I-kappa B Proteins; Mice; NF-kappa B; Phenols; Phosphorylation; Polymers; Tea; Tetradecanoylphorbol Acetate; Transcriptional Activation | 2000 |
Anti-transforming nature of ascorbic acid and its derivatives examined by two-stage cell transformation using BALB/c 3T3 cells.
Topics: 3T3 Cells; Animals; Ascorbic Acid; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Methylcholanthrene; Mice; Mice, Inbred BALB C; Tetradecanoylphorbol Acetate; Time Factors; Tumor Necrosis Factor-alpha | 2000 |
Induced p21WAF1 expression acts to reverse myc myelomonocytic cell transformation.
Topics: Animals; Apoptosis; Blotting, Northern; Caffeine; Carcinogens; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Dose-Response Relationship, Drug; Electrophoresis, Agar Gel; Flow Cytometry; G1 Phase; G2 Phase; Immunohistochemistry; In Situ Nick-End Labeling; Interleukin-3; Macrophage Colony-Stimulating Factor; Mice; Mitomycin; Monocytes; Nucleic Acid Synthesis Inhibitors; Oncogene Protein p55(v-myc); Phenotype; Plasmids; Polymerase Chain Reaction; Proto-Oncogene Proteins c-myc; Retroviridae; RNA, Catalytic; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Transfection; Tumor Suppressor Protein p53 | 2000 |
Tumor promoter produces anchorage independence in mouse epidermal cells by an induction mechanism.
Topics: Animals; Carcinogens; Cell Adhesion; Cell Line; Cell Transformation, Neoplastic; Epidermal Cells; Epidermis; Mice; Tetradecanoylphorbol Acetate | 1980 |
[p53 gene mutations in mouse skin tumors induced by DMBA-TPA-MNNG].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Exons; Genes, p53; Methylnitronitrosoguanidine; Mice; Mice, Inbred SENCAR; Papilloma; Point Mutation; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1998 |
Investigation of the mechanism for enhancement of radiation transformation in vitro by 12-O-tetradecanoylphorbol-13-acetate.
Topics: Animals; Carcinogens; Cell Line, Transformed; Cell Transformation, Neoplastic; Cells, Cultured; Cocarcinogenesis; DNA Damage; Dose-Response Relationship, Radiation; Fibroblasts; Mice; Mice, Inbred C3H; Radiation-Sensitizing Agents; Tetradecanoylphorbol Acetate | 1980 |
A novel transformation suppressor, Pdcd4, inhibits AP-1 transactivation but not NF-kappaB or ODC transactivation.
Topics: Animals; Apoptosis Regulatory Proteins; Cell Transformation, Neoplastic; Genes, Tumor Suppressor; Mice; NF-kappa B; Ornithine Decarboxylase; Proteins; RNA-Binding Proteins; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcriptional Activation | 2001 |
Novel tumor-promoting property of tamoxifen.
Topics: Animals; Carcinogens; Cell Division; Cell Line; Cell Transformation, Neoplastic; Down-Regulation; Endometrial Neoplasms; Estradiol Congeners; Female; Fibroblasts; Gene Expression Regulation, Neoplastic; Genes, src; Humans; Neoplasms; Protein Kinase C; Protein Kinase C-delta; Rats; Tamoxifen; Tetradecanoylphorbol Acetate | 2001 |
Suppression of skin tumorigenesis in c-Jun NH(2)-terminal kinase-2-deficient mice.
Topics: Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; DNA; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinase 9; Mitogen-Activated Protein Kinases; Papilloma; Phosphorylation; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factor AP-1 | 2001 |
Transformation nonresponsive cells owe their resistance to lack of p65/nuclear factor-kappaB activation.
Topics: Animals; Carcinogens; Cell Line; Cell Nucleus; Cell Transformation, Neoplastic; DNA; DNA-Binding Proteins; Humans; I-kappa B Proteins; Mice; NF-kappa B; NF-kappa B p50 Subunit; NF-KappaB Inhibitor alpha; Skin; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription Factor RelA; Transcriptional Activation; Tumor Necrosis Factor-alpha | 2001 |
[Phorbol-12-myristate-13-acetate and interferon-gamma synergistic induction of B7-1 expression in ovary carcinoma cells and immunological value].
Topics: B7-1 Antigen; Cell Transformation, Neoplastic; Cystadenocarcinoma, Mucinous; Cystadenocarcinoma, Serous; Drug Synergism; Female; Humans; Interferon-gamma; Ovarian Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1999 |
Improvement of in vitro two-stage transformation assay and determination of the promotional effect of cadmium.
Topics: 3T3 Cells; Animals; Cadmium; Carcinogenicity Tests; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; In Vitro Techniques; Methylnitronitrosoguanidine; Mice; Mice, Inbred BALB C; Polychlorinated Dibenzodioxins; Tetradecanoylphorbol Acetate; Time Factors | 2001 |
Omega 3 but not omega 6 fatty acids inhibit AP-1 activity and cell transformation in JB6 cells.
Topics: Animals; Cell Adhesion; Cell Line; Cell Transformation, Neoplastic; Epidermal Growth Factor; Fatty Acids, Omega-3; Fatty Acids, Omega-6; Fatty Acids, Unsaturated; Genes, Reporter; JNK Mitogen-Activated Protein Kinases; Kinetics; Luciferases; Mice; Mitogen-Activated Protein Kinases; Oligodeoxyribonucleotides; p38 Mitogen-Activated Protein Kinases; Skin; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcriptional Activation; Transfection | 2001 |
Suppression of cell transformation and induction of apoptosis by caffeic acid phenethyl ester.
Topics: Animals; Apoptosis; Blotting, Western; Boron Compounds; Caffeic Acids; Carcinogens; Caspase 3; Caspases; Cell Division; Cell Line; Cell Transformation, Neoplastic; DNA Fragmentation; Dose-Response Relationship, Drug; Humans; Methacrylates; Methylmethacrylates; Mice; Phenylethyl Alcohol; Phosphorylation; Precipitin Tests; Serine; Tetradecanoylphorbol Acetate; Time Factors; Transcription, Genetic; Transfection; Tumor Suppressor Protein p53 | 2001 |
Influence of beta1 integrins on epidermal squamous cell carcinoma formation in a transgenic mouse model: alpha3beta1, but not alpha2beta1, suppresses malignant conversion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, CD; Antigens, Neoplasm; Basigin; Carcinogens; Carcinoma, Squamous Cell; Cell Division; Cell Transformation, Neoplastic; Female; Integrin alpha3beta1; Integrins; Keratinocytes; Membrane Glycoproteins; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Transgenic; Papilloma; Receptors, Collagen; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tetraspanin 28 | 2001 |
Micronucleus induction in Syrian hamster embryo cells following exposure to 50 Hz magnetic fields, benzo(a)pyrene, and TPA in vitro.
Topics: Animals; Benzo(a)pyrene; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Dose-Response Relationship, Drug; Electromagnetic Fields; Embryo, Mammalian; Mesocricetus; Micronucleus Tests; Mitotic Index; Mutagens; Tetradecanoylphorbol Acetate | 2001 |
Modulation of radiation induced transformation by combinations of a phorbol diester and a lymphotoxin.
Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Embryo, Mammalian; Lymphotoxin-alpha; Mesocricetus; Neoplasms, Radiation-Induced; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 1984 |
Two novel glycosides from the fruits of Morinda citrifolia (noni) inhibit AP-1 transactivation and cell transformation in the mouse epidermal JB6 cell line.
Topics: Animals; Anticarcinogenic Agents; Cell Adhesion; Cell Line; Cell Transformation, Neoplastic; DNA; Epidermal Growth Factor; Fruit; Glucosides; Glycosides; Mice; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Plant Extracts; Plants, Medicinal; Proto-Oncogene Proteins c-jun; Rubiaceae; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcriptional Activation | 2001 |
p-Nonylphenol acts as a promoter in the BALB/3T3 cell transformation.
Topics: 3T3 Cells; Animals; Carcinogens; Cell Transformation, Neoplastic; Cocarcinogenesis; Environmental Pollutants; Estradiol; Methylcholanthrene; Mice; Phenols; Receptors, Estrogen; Tetradecanoylphorbol Acetate | 2001 |
Transactivation of the epidermal growth factor receptor is involved in 12-O-tetradecanoylphorbol-13-acetate-induced signal transduction.
Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Embryo, Mammalian; Enzyme Inhibitors; ErbB Receptors; Ligands; Mice; Mitogen-Activated Protein Kinases; Models, Biological; Phenylalanine; Phosphorylation; Protein Binding; Protein Structure, Tertiary; Quinazolines; Signal Transduction; Tetradecanoylphorbol Acetate; Thiophenes; Transcription Factor AP-1; Transcriptional Activation; Tyrphostins | 2001 |
Discrete roles of cytokines, TNF-alpha, IL-1, IL-6 in tumor promotion and cell transformation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Division; Cell Transformation, Neoplastic; DNA Primers; Female; Humans; Interleukin-1; Interleukin-6; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Okadaic Acid; Polymerase Chain Reaction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transfection; Tumor Necrosis Factor-alpha | 2002 |
Regulation of the differentiation-related gene Drg-1 during mouse skin carcinogenesis.
Topics: Animals; Carcinogens; Cell Cycle Proteins; Cell Differentiation; Cell Transformation, Neoplastic; Genes, ras; Intracellular Signaling Peptides and Proteins; Keratinocytes; Mice; Mice, Inbred C57BL; Papilloma; RNA, Messenger; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2001 |
Induction of cyclooxygenase-2 by tumor promoters in transformed and cytochrome P450 2E1-expressing hepatocytes.
Topics: Animals; Blotting, Western; Carcinogens; CCAAT-Enhancer-Binding Proteins; Cell Line, Transformed; Cell Transformation, Neoplastic; Chenodeoxycholic Acid; Cyclooxygenase 2; Cytochrome P-450 CYP2E1; Electrophoretic Mobility Shift Assay; Enzyme Induction; Hepatocytes; Inflammation; Isoenzymes; Mitogen-Activated Protein Kinases; NF-kappa B; Phosphatidylinositol 3-Kinases; Prostaglandin-Endoperoxide Synthases; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate | 2002 |
Transactivation of Fra-1 and consequent activation of AP-1 occur extracellular signal-regulated kinase dependently.
Topics: Animals; Base Sequence; Binding Sites; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Genes, fos; Genetic Variation; Mice; Mitogen-Activated Protein Kinases; Plasmids; Protein Structure, Tertiary; Proto-Oncogene Proteins c-fos; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcriptional Activation | 2002 |
Ser-10 phosphorylation of histone H3 and immediate early gene expression in oncogene-transformed mouse fibroblasts.
Topics: 3T3 Cells; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Transformation, Neoplastic; Epidermal Growth Factor; Fibroblasts; Gene Expression Regulation; Genes, fos; Genes, Immediate-Early; Histones; MAP Kinase Signaling System; Mice; Phosphorylation; ras Proteins; Ribosomal Protein S6 Kinases; Ribosomal Protein S6 Kinases, 90-kDa; Serine; Tetradecanoylphorbol Acetate; Urokinase-Type Plasminogen Activator | 2002 |
Antileukemia activity of perillyl alcohol (POH): uncoupling apoptosis from G0/G1 arrest suggests that the primary effect of POH on Bcr/Abl-transformed cells is to induce growth arrest.
Topics: Amiloride; Animals; Apoptosis; Cell Line, Transformed; Cell Transformation, Neoplastic; Cytoplasm; DNA Fragmentation; Enzyme Inhibitors; Fusion Proteins, bcr-abl; G1 Phase; Hematopoietic Stem Cells; Hydrogen-Ion Concentration; Interleukin-3; Lovastatin; Membrane Lipids; Mice; Monoterpenes; Naphthalenes; Neoplastic Stem Cells; Phosphatidylserines; Phosphorylation; Protein Processing, Post-Translational; Recombinant Fusion Proteins; Resting Phase, Cell Cycle; Signal Transduction; Sodium-Hydrogen Exchangers; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate | 2002 |
Tumour promoter alone induces neoplastic transformation of fibroblasts from humans genetically predisposed to cancer.
Topics: Animals; Cell Adhesion; Cell Transformation, Neoplastic; Eye; Humans; Mice; Mice, Nude; Multiple Endocrine Neoplasia; Neoplasm Transplantation; Neoplasms, Experimental; Phorbols; Tetradecanoylphorbol Acetate | 1979 |
Specificity of response in hamster cells induced to produce plasminogen activator by the tumor promoter, 12-O-tetradecanoylphorbol-13-acetate.
Topics: Animals; Antibodies; Cell Transformation, Neoplastic; Cricetinae; Epitopes; Immunoglobulin G; Lung; Organ Specificity; Phorbols; Plasminogen Activators; Simian virus 40; Tetradecanoylphorbol Acetate | 1978 |
Two-stage (initiation-promotion) carcinogenesis in vivo and in vitro.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzopyrenes; Cell Transformation, Neoplastic; Cells, Cultured; Cocarcinogenesis; Croton Oil; Female; In Vitro Techniques; Mice; Models, Biological; Neoplasms, Experimental; Rats; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1978 |
Phenotypic properties and tumor promotor-induced alterations in rat embryo cells transformed by adenovirus.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoviruses, Human; Animals; Benzopyrenes; Cell Aggregation; Cell Division; Cell Transformation, Neoplastic; Cell Transformation, Viral; Clone Cells; Cocarcinogenesis; Concanavalin A; Embryo, Mammalian; Membrane Proteins; Phenotype; Phorbols; Plasminogen Activators; Rats; Tetradecanoylphorbol Acetate | 1979 |
Tumor persistence and regression in skin carcinogenesis. An experimental study.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Female; Mice; Neoplasm Regression, Spontaneous; Neoplasms, Experimental; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1978 |
The effect of phorbol diesters on chicken embryo fibroblasts.
Topics: Animals; Avian Sarcoma Viruses; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Chick Embryo; Deoxyglucose; Fibroblasts; Mitosis; Models, Biological; Phorbol Esters; Phorbols; Sarcoma, Experimental; Tetradecanoylphorbol Acetate; Time Factors; Tumor Virus Infections | 1977 |
Metabolism of acetylcholine receptor in chick embryo muscle cells: effects of RSV and PMA.
Topics: Animals; Avian Sarcoma Viruses; Cell Survival; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Chick Embryo; Culture Media; Defective Viruses; Kinetics; Membrane Proteins; Muscles; Phorbols; Receptors, Cholinergic; Tetradecanoylphorbol Acetate | 1978 |
Plasminogen activator in chick embryo muscle cells: induction of enzyme by RSV, PMA and retinoic acid.
Topics: Animals; Avian Sarcoma Viruses; Bucladesine; Cell Differentiation; Cell Fusion; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; Chick Embryo; Cholera Toxin; Muscles; Phorbols; Plasminogen Activators; Tetradecanoylphorbol Acetate; Tretinoin; Vitamin A | 1978 |
Is the product of the src gene a promoter?
Topics: Avian Sarcoma Viruses; Cell Transformation, Neoplastic; Cell Transformation, Viral; Deoxyglucose; DNA; Genes, Viral; Models, Biological; Phorbols; Tetradecanoylphorbol Acetate | 1979 |
Modulation of plasminogen activator synthesis in chick embryo fibroblasts by cyclic nucleotides and phorobol myristate acetate.
Topics: Animals; Avian Sarcoma Viruses; Bucladesine; Cell Transformation, Neoplastic; Cells, Cultured; Chick Embryo; Cholera Toxin; Cyclic AMP; Fibroblasts; Phorbols; Plasminogen Activators; Tetradecanoylphorbol Acetate | 1979 |
Decrease in collagen production in normal and Rous sarcoma virus-transformed chick embryo fibroblasts induced by phorbol myristate acetate.
Topics: Animals; Avian Sarcoma Viruses; Cell Differentiation; Cell Transformation, Neoplastic; Cells, Cultured; Chick Embryo; Collagen; Dimethyl Sulfoxide; Fibroblasts; Phorbols; Tetradecanoylphorbol Acetate | 1979 |
The roles of the simian virus 40 tumor antigens in transformation of Chinese hamster lung cells.
Topics: Animals; Antigens, Neoplasm; Antigens, Viral; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Lung; Mice; Mice, Nude; Mutation; Neoplasm Transplantation; Neoplasms, Experimental; Simian virus 40; Tetradecanoylphorbol Acetate; Transplantation, Heterologous | 1979 |
T-antigen expression in proliferating and non-proliferating simian virus 40-transformed mouse cells.
Topics: Animals; Antigens, Viral; Cell Cycle; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cycloheximide; Cytarabine; Dactinomycin; DNA, Viral; Mice; Simian virus 40; Temperature; Tetradecanoylphorbol Acetate | 1979 |
Relationship between Rous sarcoma virus-induced expression of membrane antigen and phenotypic transformation.
Topics: Animals; Antigens, Surface; Antigens, Viral; Avian Sarcoma Viruses; Bucladesine; Cell Line; Cell Transformation, Neoplastic; Cricetinae; Genes; Phenotype; Tetradecanoylphorbol Acetate | 1979 |
Interactions between adenovirus, a tumor promoter, and chemical carcinogens in transformation of rat embryo cell cultures.
Topics: Adenoviruses, Human; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Cocarcinogenesis; Phorbols; Polycyclic Compounds; Tetradecanoylphorbol Acetate; Time Factors | 1978 |
Tumor promoter induces sister chromatid exchanges: relevance to mechanisms of carcinogenesis.
Topics: Cell Line; Cell Transformation, Neoplastic; Chromatids; Chromosome Aberrations; Chromosomes; Crossing Over, Genetic; Fluocinolone Acetonide; Leupeptins; Phorbols; Recombination, Genetic; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1978 |
Tumor promoters: carcinogenesis gets more complicated.
Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Cocarcinogenesis; Dietary Fats; Epidermal Growth Factor; Humans; Neoplasms; Ornithine Decarboxylase; Phenobarbital; Plasminogen Activators; Receptors, Drug; Saccharin; Smoking; Tetradecanoylphorbol Acetate | 1978 |
Tumor promoters and epidermal growth factor stimulate anchorage-independent growth of adenovirus-tranformed rat embryo cells.
Topics: Adenoviruses, Human; Animals; Cell Adhesion; Cell Division; Cell Transformation, Neoplastic; Clone Cells; Dexamethasone; Diterpenes; Embryo, Mammalian; Epidermal Growth Factor; Peptides; Phorbols; Protease Inhibitors; Rats; Tetradecanoylphorbol Acetate; Tretinoin | 1979 |
Epidermal intercellular relationships during carcinogenesis and cocarcinogenesis as revealed by scanning electron microscopy.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Autoradiography; Cell Transformation, Neoplastic; Cocarcinogenesis; Epithelium; Extracellular Space; Female; Hyperplasia; Intercellular Junctions; Mice; Microscopy, Electron, Scanning; Skin; Tetradecanoylphorbol Acetate | 1977 |
DNA repair and malignant transformation: effect of X irradiation, 12-O-tetradecanoyl-phorbol-13-acetate, and protease inhibitors on transformation and sister-chromatid exchanges in mouse 10T 1/2 cells.
Topics: Animals; Antipain; Cell Survival; Cell Transformation, Neoplastic; Chromosome Aberrations; DNA Repair; Dose-Response Relationship, Radiation; In Vitro Techniques; Leupeptins; Mice; Phorbols; Protease Inhibitors; Sister Chromatid Exchange; Tetradecanoylphorbol Acetate; X-Rays | 1979 |
Tumour promoter induces anchorage independence irreversibly.
Topics: Animals; Antigens, Surface; Cell Adhesion; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Dose-Response Relationship, Drug; Epidermal Cells; Epidermis; Mice; Phorbol Esters; Phorbols; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1979 |
Effects of tumor-promoting phorbol diesters on hamster cells in culture.
Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; DNA; Embryo, Mammalian; Enzyme Induction; Inactivation, Metabolic; Mesocricetus; Mice; Ornithine Decarboxylase; Phorbol Esters; Phorbols; Skin; Tetradecanoylphorbol Acetate | 1979 |
Effects of promoters on DNA synthesis in C3H/10T1/2 mouse fibroblasts.
Topics: Animals; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; DNA; Fibroblasts; Methylcholanthrene; Mice; Phorbol Esters; Phorbols; Tetradecanoylphorbol Acetate; Thymidine | 1977 |
Effects of a tumor-promoting agent on chondrogenesis.
Topics: Animals; Carcinogens; Cartilage; Cell Division; Cell Line; Cell Transformation, Neoplastic; Chickens; Phorbols; Proteoglycans; Tetradecanoylphorbol Acetate | 1977 |
Enhancement of X-ray transformation by 12-O-tetradecanoyl-phorbol-13-acetate in a cloned line of C3H mouse embryo cells.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Clone Cells; Dose-Response Relationship, Radiation; In Vitro Techniques; Mice; Mice, Inbred C3H; Neoplasms, Radiation-Induced; Phorbols; Tetradecanoylphorbol Acetate; Time Factors | 1978 |
Correlation of anchorage-independent growth with tumorigenicity of chemically transformed mouse epidermal cells.
Topics: Agar; Animals; Cell Adhesion; Cell Division; Cell Transformation, Neoplastic; Clone Cells; Methylnitronitrosoguanidine; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Neoplasms, Experimental; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transplantation, Isogeneic | 1978 |
A cell culture bioassay to analyze metabolism of phorbol diester tumor promoters.
Topics: Animals; Carboxy-Lyases; Cell Transformation, Neoplastic; Cells, Cultured; Chick Embryo; Chromatography, Thin Layer; Cricetinae; Fibroblasts; Humans; Mice; Ornithine Decarboxylase; Phorbol Esters; Phorbols; Rats; Species Specificity; Tetradecanoylphorbol Acetate | 1978 |
Mechanism of growth arrest of chemically transformed cells in culture.
Topics: Amino Acids; Cell Cycle; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Culture Media; DNA, Neoplasm; Glucose; Growth Substances; Tetradecanoylphorbol Acetate; Thymidine; Time Factors | 1978 |
Enhancement of oncogenesis in C3H/10T1/2 mouse embryo cell cultures by saccharin.
Topics: Animals; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Cocarcinogenesis; Embryo, Mammalian; Methylcholanthrene; Mice; Mice, Inbred C3H; Saccharin; Tetradecanoylphorbol Acetate | 1978 |
Establishment of epithelial cell lines following exposure of cultured tracheal epithelium to 12-O-tetradecanoyl-phorbol-13-acetate.
Topics: Animals; Cell Division; Cell Line; Cell Transformation, Neoplastic; Epithelium; Phorbols; Rats; Tetradecanoylphorbol Acetate; Time Factors; Trachea | 1978 |
Ultraviolet light in the oncogenic transformation of cultured C3H/10T1/2 mouse embryo cells.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Cocarcinogenesis; Dose-Response Relationship, Radiation; Embryo, Mammalian; Fibroblasts; Mice; Tetradecanoylphorbol Acetate; Time Factors; Ultraviolet Rays | 1978 |
Two-stage malignant transformation in hamster embryo cells.
Topics: Agar; Animals; Benz(a)Anthracenes; Cell Transformation, Neoplastic; Cricetinae; Methylcholanthrene; Neoplasm Transplantation; Neoplasms, Experimental; Phorbols; Tetradecanoylphorbol Acetate; Time Factors | 1979 |
Two-stage chemical oncogenesis in cultures of C3H/10T1/2 cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Benzopyrenes; Cell Transformation, Neoplastic; Cells, Cultured; Drug Administration Schedule; Methylcholanthrene; Phorbol Esters; Phorbols; Tetradecanoylphorbol Acetate | 1976 |
Ornithine decarboxylase induction and DNA synthesis in hamster embryo cell cultures treated with tumor-promoting phorbol diesters.
Topics: Carboxy-Lyases; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; DNA; Enzyme Induction; Ornithine Decarboxylase; Phorbols; Putrescine; Spermidine; Spermine; Tetradecanoylphorbol Acetate | 1977 |
Effect of a phorbol ester on a transformation-sensitive surface protein of chick fibroblasts.
Topics: Animals; Cell Division; Cell Membrane; Cell Transformation, Neoplastic; Cells, Cultured; Chick Embryo; Fibroblasts; Membrane Proteins; Phorbols; Tetradecanoylphorbol Acetate; Time Factors | 1976 |
Tumour promotor induces plasminogen activator.
Topics: Cell Transformation, Neoplastic; Fibroblasts; HeLa Cells; Phorbols; Plasminogen Activators; Tetradecanoylphorbol Acetate | 1976 |
Embryonic stem (ES) cells lacking functional c-jun: consequences for growth and differentiation, AP-1 activity and tumorigenicity.
Topics: Alleles; Animals; Base Sequence; Cell Differentiation; Cell Division; Cell Line; Cell Transformation, Neoplastic; Chloramphenicol O-Acetyltransferase; DNA; Embryo, Mammalian; Gene Expression; Genes, jun; Genetic Vectors; Mice; Mice, Inbred Strains; Molecular Sequence Data; Neoplasm Transplantation; Oligodeoxyribonucleotides; Polymerase Chain Reaction; Proto-Oncogene Proteins c-jun; Restriction Mapping; RNA; Stem Cells; Teratoma; Tetradecanoylphorbol Acetate; Transfection | 1992 |
Expression of genes encoding type IV collagen-degrading metalloproteinases and tissue inhibitors of metalloproteinases in various human tumor cells.
Topics: Cell Transformation, Neoplastic; Fibroblasts; Gene Expression Regulation, Enzymologic; Glycoproteins; Humans; Matrix Metalloproteinase 9; Microbial Collagenase; Neoplasms; RNA, Messenger; Tetradecanoylphorbol Acetate; Tissue Inhibitor of Metalloproteinases; Tumor Cells, Cultured | 1992 |
Expression of high affinity binding sites for erythropoietin on L8057 cells, a mouse megakaryoblastic cell line, associated with cell differentiation.
Topics: Acetylcholinesterase; Animals; Antigens; Cell Differentiation; Cell Transformation, Neoplastic; DNA, Neoplasm; Erythropoietin; Iodine Radioisotopes; Leucine; Leukemia, Experimental; Leukemia, Megakaryoblastic, Acute; Megakaryocytes; Mice; Platelet Membrane Glycoproteins; Protein Binding; Receptors, Cell Surface; Receptors, Erythropoietin; Recombinant Proteins; Tetradecanoylphorbol Acetate; Thymidine; Tumor Cells, Cultured | 1992 |
A tobacco-specific N-nitrosamine or cigarette smoke condensate causes neoplastic transformation of xenotransplanted human bronchial epithelial cells.
Topics: Animals; Biomarkers, Tumor; Bronchi; Carcinogens; Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; Chemotaxis; Epithelium; ErbB Receptors; Gelatinases; Humans; Isoenzymes; Lung Neoplasms; Mice; Mice, Nude; Neoplasm Invasiveness; Nitrosamines; Pepsin A; Rats; Smoke; Smoking; Tetradecanoylphorbol Acetate; Trachea; Transforming Growth Factor alpha; Transplantation, Heterologous | 1992 |
Phospholipase D activity in nontransformed and transformed fibroblasts.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Cell-Free System; Fibroblasts; Kinetics; Lipid Metabolism; Lipids; Myristic Acid; Myristic Acids; Phospholipase D; Rats; Simian virus 40; Tetradecanoylphorbol Acetate | 1992 |
Interleukin 1 alpha mediated inhibition of myogenic terminal differentiation: increased sensitivity of Ha-ras transformed cultures.
Topics: Actins; Animals; Cell Differentiation; Cell Line, Transformed; Cell Transformation, Neoplastic; Depression, Chemical; Fibroblasts; Gene Expression Regulation, Neoplastic; Interleukin-1; Mice; Mice, Inbred C3H; Muscle Proteins; Muscles; MyoD Protein; Myogenin; Nuclear Proteins; Phosphoproteins; Protein Kinase C; Proto-Oncogene Proteins p21(ras); Tetradecanoylphorbol Acetate | 1992 |
The SH2 and SH3 domain-containing Nck protein is oncogenic and a common target for phosphorylation by different surface receptors.
Topics: 3T3 Cells; Adaptor Proteins, Signal Transducing; Animals; Cell Line; Cell Transformation, Neoplastic; Epidermal Growth Factor; Humans; Mice; Oncogene Proteins; Organ Specificity; Phosphorylation; Platelet-Derived Growth Factor; Precipitin Tests; Protein-Tyrosine Kinases; Rats; Receptors, Cell Surface; Signal Transduction; Sulfhydryl Compounds; Tetradecanoylphorbol Acetate; Transfection; Vanadates | 1992 |
Effect of TPA, okadaic acid and 1 alpha,25-dihydroxyvitamin D3 on neoplastic transformation induced by 60Co gamma-rays or 252Cf fission neutrons in Balb/c 3T3 cells.
Topics: 3T3 Cells; Animals; Calcitriol; Cell Transformation, Neoplastic; Ethers, Cyclic; Gamma Rays; Mice; Mice, Inbred BALB C; Neutrons; Okadaic Acid; Tetradecanoylphorbol Acetate | 1992 |
Development of an in vitro model to study carcinogen-induced neoplastic progression of initiated mouse epidermal cells.
Topics: Animals; Animals, Newborn; Base Sequence; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cells, Cultured; Epidermal Cells; Epidermis; Genes, ras; Keratinocytes; Keratins; Methylnitronitrosoguanidine; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Oligodeoxyribonucleotides; Papilloma; Polymerase Chain Reaction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transfection | 1992 |
Transcripts encoding protein kinase C-alpha, -delta, -epsilon, -zeta, and -eta are expressed in basal and differentiating mouse keratinocytes in vitro and exhibit quantitative changes in neoplastic cells.
Topics: Animals; Animals, Newborn; Blotting, Northern; Calcium; Cell Differentiation; Cell Transformation, Neoplastic; Cells, Cultured; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Genes, ras; Humans; Isoenzymes; Keratinocytes; Mice; Poly A; Protein Kinases; RNA; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 1992 |
Spontaneous malignant transformation of melanocytes explanted from Wf/Wf mice with a Kit kinase-domain mutation.
Topics: Animals; Base Sequence; Cell Death; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Genes, Dominant; Genotype; Melanocytes; Melanoma, Experimental; Mice; Mice, Inbred C3H; Mice, Mutant Strains; Molecular Sequence Data; Mutation; Oligodeoxyribonucleotides; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-kit; Proto-Oncogenes; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1992 |
Absence of PDGF-induced, PKC-independent c-fos expression in a chemically transformed C3H/10T1/2 cell clone.
Topics: Adenosine Triphosphate; Animals; Blotting, Northern; Cell Transformation, Neoplastic; Clone Cells; Deoxycytosine Nucleotides; DNA Probes; DNA Replication; Genes, fos; Kinetics; Mice; Mice, Inbred C3H; Phosphorus Radioisotopes; Platelet-Derived Growth Factor; Protein Kinase C; Receptors, Cell Surface; Receptors, Platelet-Derived Growth Factor; RNA; RNA, Messenger; Swine; Tetradecanoylphorbol Acetate; Thymidine | 1992 |
Effect of cAMP elevating compounds on inhibition of gap junctional communication and induction of morphological transformation in Syrian hamster embryo cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cell Communication; Cell Transformation, Neoplastic; Cells, Cultured; Cholera Toxin; Colforsin; Cricetinae; Cyclic AMP; Embryo, Mammalian; Intercellular Junctions; Mesocricetus; Tetradecanoylphorbol Acetate; Theophylline | 1992 |
Analysis of temperature-sensitive functions of Fos: lack of a correlation between transformation and TRE-dependent trans-activation.
Topics: Cell Transformation, Neoplastic; DNA; Gene Expression; HeLa Cells; Humans; Mutation; Oncogene Proteins v-fos; Proto-Oncogene Proteins c-jun; Temperature; Tetradecanoylphorbol Acetate; Transcriptional Activation | 1992 |
Carba-prostacyclin inhibits 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced transformation in sensitive murine epidermal JB6 cells.
Topics: Animals; Cell Adhesion; Cell Transformation, Neoplastic; Cells, Cultured; Epidermal Cells; Epidermis; Epoprostenol; Kinetics; Mice; Sensitivity and Specificity; Stem Cells; Tetradecanoylphorbol Acetate | 1992 |
Cell-transforming potential of low-density lipoproteins.
Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Fibroblasts; Lipoproteins, HDL; Lipoproteins, LDL; Methylcholanthrene; Mice; Mice, Inbred C3H; Tetradecanoylphorbol Acetate | 1992 |
Transformation of non-tumorigenic osteoblast-like human osteosarcoma cells by hexavalent chromates: alteration of morphology, induction of anchorage-independence and proteolytic function.
Topics: Animals; Carcinogens; Cell Adhesion; Cell Division; Cell Survival; Cell Transformation, Neoplastic; Chromates; Electrochemistry; Humans; Hydrolysis; Male; Methylcholanthrene; Mice; Mice, Nude; Neoplasms, Experimental; Osteoblasts; Osteosarcoma; Plasminogen Activators; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Urokinase-Type Plasminogen Activator | 1992 |
Transformed growth phenotype of mouse mammary epithelium in primary culture induced by specific fetal mesenchymes.
Topics: Animals; Cell Transformation, Neoplastic; Culture Techniques; Cytological Techniques; Epithelial Cells; Epithelium; Fetal Tissue Transplantation; Mammary Glands, Animal; Mesoderm; Mice; Mice, Inbred BALB C; Phenotype; Sepharose; Stem Cells; Stromal Cells; Tetradecanoylphorbol Acetate | 1992 |
AP-1 (Fos-Jun) regulation by IP-1: effect of signal transduction pathways and cell growth.
Topics: 3T3 Cells; Animals; Blood Physiological Phenomena; Calcium; Cell Transformation, Neoplastic; Cycloheximide; DNA; Genes, fos; Genes, jun; Humans; Mice; Protein Kinase C; Protein Kinases; Proteins; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-jun; Signal Transduction; Tetradecanoylphorbol Acetate; Tretinoin | 1992 |
Differential induction of c-fos and c-jun proto-oncogenes and AP-1 activity by tumor promoter 12-O-tetradecanoyl phorbol 13-acetate in cells at different stages of tumor promotion in vitro.
Topics: Animals; Base Sequence; Cell Transformation, Neoplastic; Cells, Cultured; DNA; Down-Regulation; Gene Expression Regulation; Genes, fos; Mice; Molecular Sequence Data; Protein Kinase C; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Proto-Oncogenes; Tetradecanoylphorbol Acetate | 1992 |
Identification and quantification of a carcinogen-induced molecular initiation event in cell transformation.
Topics: 3T3 Cells; 9,10-Dimethyl-1,2-benzanthracene; Animals; Base Sequence; Carcinogens; Cell Transformation, Neoplastic; Gene Expression; Genes, ras; Mice; Molecular Sequence Data; Mutation; Tetradecanoylphorbol Acetate | 1992 |
Malignant transformation of human melanocytes: induction of a complete melanoma phenotype and genotype.
Topics: 3T3 Cells; Animals; Antigens, Surface; Cell Transformation, Neoplastic; Chromosome Aberrations; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 6; Genes, ras; Genotype; HLA-DR Antigens; Humans; Melanocytes; Melanoma; Mice; Phenotype; Tetradecanoylphorbol Acetate | 1992 |
Role of the 21-kDa protein TIMP-3 in oncogenic transformation of cultured chicken embryo fibroblasts.
Topics: Animals; Cell Adhesion; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Chick Embryo; Extracellular Matrix; Fibroblasts; Histones; Metalloendopeptidases; Models, Biological; Molecular Weight; Neoplasm Proteins; Tetradecanoylphorbol Acetate; Tissue Inhibitor of Metalloproteinase-3 | 1992 |
12-O-tetradecanoylphorbol-13-acetate--induced levels of AP-1 proteins: a 46-kDa protein immunoprecipitated by anti-fra-1 and induced in promotion-resistant but not promotion-sensitive JB6 cells.
Topics: Amino Acid Sequence; Animals; Cell Line; Cell Transformation, Neoplastic; Electrophoresis, Polyacrylamide Gel; Gene Expression Regulation, Neoplastic; Mice; Molecular Sequence Data; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors; Transcriptional Activation | 1992 |
Epigenetic activation of Gi-2 protein, the product of a putative protooncogene, mediates tumor promotion in vitro.
Topics: Adrenal Gland Neoplasms; Amino Acid Sequence; Animals; Cell Transformation, Neoplastic; Cells, Cultured; Epidermal Growth Factor; Female; GTP-Binding Proteins; Mice; Molecular Sequence Data; Mutation; Ovarian Neoplasms; Pertussis Toxin; Phenotype; Phospholipases A; Phospholipases A2; Proto-Oncogene Proteins; Rats; Sequence Homology, Amino Acid; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha; Virulence Factors, Bordetella | 1992 |
Phenotypic expression of carcinogen-initiated epidermal cells to tumor cells by 12-O-tetradecanoylphorbol-13-acetate in a manner dependent on 3T3 fibroblast-derived humoral factor(s).
Topics: 3T3 Cells; 9,10-Dimethyl-1,2-benzanthracene; Animals; Calcium; Cell Transformation, Neoplastic; Cells, Cultured; Epidermis; Macrophages; Mice; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1992 |
Differential c-jun expression in response to tumor promoters in JB6 cells sensitive or resistant to neoplastic transformation.
Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Epidermal Growth Factor; Gene Expression; Genes, fos; Genes, jun; In Vitro Techniques; Mice; Neoplasm Transplantation; Proto-Oncogene Proteins c-jun; RNA, Messenger; Tetradecanoylphorbol Acetate | 1992 |
Dissociation of nuclear events on p21 RAS transformation of FDC-P1 myeloid cells: c-jun/AP-1 expression versus c-myc transcription.
Topics: Cell Line; Cell Nucleus; Cell Transformation, Neoplastic; Enhancer Elements, Genetic; Enzyme Activation; Genes, myc; Humans; Interleukin-3; Protein Kinase C; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Proto-Oncogene Proteins p21(ras); Tetradecanoylphorbol Acetate; Transcription, Genetic | 1992 |
Differential induction of 15 and 16 kDa nuclear proteins in promotion sensitive and promotion resistant mouse JB6 cells.
Topics: Animals; Carcinogens; Cell Line; Cell Transformation, Neoplastic; In Vitro Techniques; Mice; Molecular Weight; Nuclear Proteins; Tetradecanoylphorbol Acetate | 1992 |
Transformation and transactivation suppressor activity of the c-Jun leucine zipper fused to a bacterial repressor.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Bacterial Proteins; Cell Transformation, Neoplastic; Chloramphenicol O-Acetyltransferase; Choriocarcinoma; Escherichia coli; Genes, ras; Genes, Regulator; Humans; Leucine Zippers; Mice; Mutagenesis; Proto-Oncogene Proteins c-jun; Recombinant Fusion Proteins; Repressor Proteins; Restriction Mapping; Serine Endopeptidases; Suppression, Genetic; Tetradecanoylphorbol Acetate; Transfection | 1992 |
Monoclonal anti-melanoma antibodies IKH-1 and IKH-2 which work on formalin-fixed, paraffin embedded tissues: characterization, clinical trials and comparative studies with HMB-45.
Topics: Animals; Antibodies, Monoclonal; Antigens, Neoplasm; Biomarkers, Tumor; Cell Transformation, Neoplastic; Clinical Trials as Topic; Formaldehyde; Humans; Hybridomas; Immunohistochemistry; Melanoma; Melanoma, Experimental; Mice; Microscopy, Immunoelectron; Paraffin; Tetradecanoylphorbol Acetate; Tissue Fixation; Tumor Cells, Cultured | 1992 |
Temporal relationships between induced changes in c-myc mRNA abundance, proliferation, and differentiation in HL60 cells.
Topics: Cell Differentiation; Cell Division; Cell Transformation, Neoplastic; Dimethyl Sulfoxide; Down-Regulation; Granulocytes; Humans; Leukemia, Experimental; Leukemia, Myeloid; Proto-Oncogene Proteins c-myc; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
Human smooth muscle myosin light chain-2 gene expression is repressed in ras transformed fibroblast cells.
Topics: Cell Line, Transformed; Cell Transformation, Neoplastic; Fibroblasts; Gene Expression Regulation, Neoplastic; Genes, ras; Humans; Muscle, Smooth; Myosins; RNA, Messenger; Stereoisomerism; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
Studies on the mechanisms of HTLV-I leukemogenesis.
Topics: Cell Transformation, Neoplastic; DNA Damage; Genes, pX; HTLV-I Infections; Humans; Leukemia, T-Cell; Methylation; Micronucleus Tests; Plasmids; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1992 |
Initiating activity of 1,1,2,2-tetrachloroethane in two-stage BALB/c 3T3 cell transformation.
Topics: 3T3 Cells; Animals; Cell Division; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Ethane; Hydrocarbons, Chlorinated; Liver Extracts; Mice; Mice, Inbred BALB C; Sister Chromatid Exchange; Tetradecanoylphorbol Acetate | 1992 |
Increased intracellular calcium is associated with progression of HPV-18 immortalized human keratinocytes to tumorigenicity.
Topics: Calcium; Cell Differentiation; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Flow Cytometry; Humans; Indoles; Keratinocytes; Papillomaviridae; Spectrometry, Fluorescence; Tetradecanoylphorbol Acetate | 1991 |
The tumor promoter 12-O-tetradecanoylphorbol-13-acetate and the ras oncogene modulate expression and phosphorylation of gap junction proteins.
Topics: Animals; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Connexins; Fluorescent Antibody Technique; Gene Expression Regulation; Genes, ras; Harvey murine sarcoma virus; Keratinocytes; Membrane Proteins; Mice; Moloney murine leukemia virus; Phosphorylation; Tetradecanoylphorbol Acetate | 1991 |
In vitro transformation of rat esophageal epithelial cells by fusarin C.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Epithelial Cells; Esophageal Neoplasms; Esophagus; Gene Expression Regulation, Neoplastic; Genes, myc; Mice; Mice, Nude; Mutagens; Oncogene Proteins v-erbB; Oncogenes; Polyenes; Rats; Rats, Inbred Strains; Retroviridae Proteins, Oncogenic; Tetradecanoylphorbol Acetate | 1991 |
Lack of effect of colony-stimulating factors, interleukins, interferons, and tumor necrosis factor on the growth and differentiation of cultured Reed-Sternberg cells. Comparison with effects of phorbol ester and retinoic acid.
Topics: Aged; Biological Factors; Cell Line; Cell Transformation, Neoplastic; Colony-Stimulating Factors; Cytokines; Hodgkin Disease; Humans; Interferons; Interleukins; Lymphoma; Male; Phorbol Esters; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Necrosis Factor-alpha | 1990 |
Oncogene alterations in in vitro transformed rat tracheal epithelial cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Blotting, Northern; Cell Line; Cell Transformation, Neoplastic; DNA; Epithelium; Gene Amplification; Gene Rearrangement; Genes, ras; Male; Nucleic Acid Hybridization; Oncogene Protein p21(ras); Oncogenes; Polymorphism, Restriction Fragment Length; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myc; Rats; RNA; Tetradecanoylphorbol Acetate; Trachea; Transfection | 1990 |
Differential phosphorylation of myelin-associated glycoprotein isoforms in cell culture.
Topics: Animals; Bucladesine; Cell Line; Cell Transformation, Neoplastic; Cyclic AMP; Epidermal Growth Factor; Insulin; Insulin-Like Growth Factor I; Mice; Myelin Proteins; Myelin-Associated Glycoprotein; Phosphorylation; Tetradecanoylphorbol Acetate; Transfection | 1990 |
Induction of monocytic differentiation by tumor necrosis factor in phorbol ester-resistant KG-1a cells.
Topics: Blotting, Northern; Cell Adhesion; Cell Adhesion Molecules; Cell Transformation, Neoplastic; Flow Cytometry; Gene Expression Regulation; Humans; In Vitro Techniques; Leukemia, Myeloid, Acute; Macrophage Colony-Stimulating Factor; Monocytes; Phospholipases A; Phospholipases A2; RNA; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1990 |
Effects of antineoplastic phospholipids on parameters of cell differentiation in U937 cells.
Topics: Antigens, Surface; Antineoplastic Agents; Blotting, Northern; Cell Transformation, Neoplastic; DNA Probes; Fatty Alcohols; Gene Expression Regulation, Neoplastic; Histones; Leukemia, Promyelocytic, Acute; Lysophosphatidylcholines; Phorbol Esters; Phospholipid Ethers; Phospholipids; Phosphorylcholine; RNA; RNA, Messenger; Tetradecanoylphorbol Acetate | 1990 |
Expression of normal and cystic fibrosis phenotypes by continuous airway epithelial cell lines.
Topics: Antigens, Polyomavirus Transforming; Base Sequence; Biomarkers; Blood Proteins; Bradykinin; Calcimycin; Calgranulin A; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Chloride Channels; Chlorides; Colforsin; Cystic Fibrosis; Epithelial Cells; Epithelium; Genotype; Humans; Ion Channels; Keratins; Membrane Potentials; Membrane Proteins; Molecular Sequence Data; Nasal Mucosa; Oligonucleotide Probes; Phenotype; Polymerase Chain Reaction; Reference Values; Retroviridae; Simian virus 40; Tetradecanoylphorbol Acetate; Theophylline | 1990 |
Constitutively activated neu oncoprotein tyrosine kinase interferes with growth factor-induced signals for gene activation.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; ErbB Receptors; Gene Expression; Genes, ras; Humans; Phosphotyrosine; Poly A; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogenes; Receptor, ErbB-2; RNA; RNA, Messenger; Tetradecanoylphorbol Acetate; Transfection; Tyrosine | 1991 |
TGF-beta 1 and skin carcinogenesis: antiproliferative effect in vitro and TGF-beta 1 mRNA expression during epidermal hyperproliferation and multistage tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Animals, Newborn; Blotting, Northern; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; DNA; DNA Replication; DNA, Neoplasm; Female; Gene Expression; Keratinocytes; Mice; Mice, Inbred Strains; Phorbol Esters; RNA; RNA, Messenger; RNA, Neoplasm; Skin; Skin Neoplasms; Skin Physiological Phenomena; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta | 1991 |
Induction of glutathione content in murine melanocytes after transformation with c-H-ras oncogene.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Genes, ras; Glutathione; Glutathione Transferase; Melanocytes; Mice; RNA; Tetradecanoylphorbol Acetate; Transfection | 1991 |
Dissociation of platelet-derived growth factor (PDGF) receptor autophosphorylation from other PDGF-mediated second messenger events.
Topics: 1-Phosphatidylinositol 4-Kinase; Animals; Calcium; Cell Division; Cell Line; Cell Transformation, Neoplastic; Chemokine CCL2; Chemotactic Factors; Cyclic AMP; DNA; Gene Expression; Genes, ras; GTP-Binding Proteins; Mice; Phosphorylation; Phosphotransferases; Phosphotyrosine; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-myc; rap GTP-Binding Proteins; Receptors, Cell Surface; Receptors, Platelet-Derived Growth Factor; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection; Type C Phospholipases; Tyrosine | 1991 |
Clinical significance of CD7-positive stem cell leukemia. A distinct subtype of mixed lineage leukemia.
Topics: Acute Disease; Adolescent; Antigens, CD; Antigens, CD7; Antigens, Differentiation, T-Lymphocyte; Cell Transformation, Neoplastic; Child; Child, Preschool; DNA, Neoplasm; Female; Gene Rearrangement; Genotype; Humans; Immunophenotyping; Infant; Karyotyping; Leukemia; Male; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1991 |
Correlation of c-fos/c-jun expression with histiocytic differentiation in Hodgkin's Reed-Sternberg cells. Examination in HDLM-1 subclones with spontaneous differentiation.
Topics: Adult; Aged; Base Sequence; Cell Transformation, Neoplastic; DNA, Neoplasm; Fluorescent Antibody Technique; Histiocytes; Hodgkin Disease; Humans; Male; Phenotype; Pleural Effusion; Proto-Oncogene Mas; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Reed-Sternberg Cells; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
Highly purified human alpha-thrombin promotes morphological transformation of BALB/c 3T3 cells.
Topics: 3T3 Cells; Animals; Cell Transformation, Neoplastic; Epidermal Growth Factor; Mice; Tetradecanoylphorbol Acetate; Thrombin | 1992 |
Transcriptional activity of rel family proteins.
Topics: Base Sequence; Cell Transformation, Neoplastic; Chloramphenicol O-Acetyltransferase; Enzyme Activation; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Viral; HeLa Cells; HIV Long Terminal Repeat; Humans; Molecular Sequence Data; Neurofibromin 1; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-rel; Tetradecanoylphorbol Acetate; Transfection | 1992 |
Synergistic inhibition of phorbol ester-induced transformation of JB6 cells by transforming growth factor-beta and retinoic acid.
Topics: Animals; Cell Division; Cell Line; Cell Transformation, Neoplastic; Colony-Forming Units Assay; Dose-Response Relationship, Drug; Drug Synergism; Mice; Mice, Inbred BALB C; Receptors, Cell Surface; Receptors, Transforming Growth Factor beta; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta; Tretinoin | 1991 |
Tumor-promoting activity of Epstein-Barr-virus-inducing factor transforming growth factor type beta (EIF/TGF-beta) is due to the induction of irreversible transformation.
Topics: Animals; Blood Platelets; Cell Line; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Herpesvirus 4, Human; Humans; Mice; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta | 1991 |
Inhibition of chemically induced neoplastic transformation in vitro by saturated fatty acids.
Topics: Animals; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Dose-Response Relationship, Drug; Fatty Acids; In Vitro Techniques; Methylcholanthrene; Oleic Acid; Oleic Acids; Rats; Tetradecanoylphorbol Acetate | 1991 |
Differential genomic susceptibility in malignancy correlates with changes in ATATAT DNA-binding proteins.
Topics: Animals; Base Sequence; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Cholera Toxin; DNA-Binding Proteins; Embryo, Mammalian; Ethers, Cyclic; Genetic Predisposition to Disease; Melanocytes; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Nuclear Proteins; Okadaic Acid; Substrate Specificity; Tetradecanoylphorbol Acetate | 1991 |
Elevation of glucose transporter, c-myc, and transin RNA levels by Ha-rasT24 is independent of its effect on the cell cycle.
Topics: Animals; Cell Cycle; Cell Line; Cell Transformation, Neoplastic; DNA Replication; Epidermal Growth Factor; Fibroblasts; G1 Phase; Gene Expression; Genes, myc; Genes, ras; Kinetics; Matrix Metalloproteinase 3; Metalloendopeptidases; Monosaccharide Transport Proteins; Neoplasm Proteins; Rats; RNA, Messenger; S Phase; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection | 1991 |
Failure of wild-type or a mutant form of protein kinase C-alpha to transform fibroblasts.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; DNA; Fibroblasts; Fibrosarcoma; Gene Expression; Mice; Mice, Inbred BALB C; Mice, Nude; Mutation; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Transfection | 1991 |
Differential regulation of the p72-74 RAF-1 kinase in 3T3 fibroblasts expressing ras or src oncogenes.
Topics: Animals; Cell Line; Cell Membrane; Cell Transformation, Neoplastic; Genes, src; In Vitro Techniques; Mice; Molecular Weight; Oncogene Protein p21(ras); Oncogene Protein pp60(v-src); Phosphoproteins; Phosphorylation; Platelet-Derived Growth Factor; Protein Kinase C; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Tetradecanoylphorbol Acetate | 1991 |
[Genetics of cancerogenesis. Experimental model in mice].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Drug Resistance; Incidence; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Phenotype; Tetradecanoylphorbol Acetate | 1991 |
Human Harvey-ras is biochemically different from Kirsten- or N-ras.
Topics: Animals; Blotting, Northern; Caenorhabditis elegans Proteins; Carrier Proteins; Cell Line; Cell Transformation, Neoplastic; Gene Expression; Genes, ras; Humans; Mice; Oncogenes; Protein Kinase C; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogenes; Receptors, Drug; RNA, Messenger; Tetradecanoylphorbol Acetate; Transfection | 1991 |
Characterization of phospholipase A2 in monocytic cell lines. Functional and biochemical aspects of membrane association.
Topics: Arachidonic Acid; Arachidonic Acids; Calcium; Cell Line; Cell Membrane; Cell Transformation, Neoplastic; Cytosol; Edetic Acid; Enzyme Activation; Humans; Leukemia, Myeloid; Magnesium; Membrane Proteins; Phospholipases A; Phospholipases A2; Substrate Specificity; Tetradecanoylphorbol Acetate | 1991 |
Activation of the rasHa gene in urethane-initiated papillomas induced by protocols with high and low frequencies of malignant conversion.
Topics: 3T3 Cells; Animals; Blotting, Southern; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; DNA, Neoplasm; Drug Interactions; Female; Gene Expression Regulation, Neoplastic; Genes, ras; Male; Mice; Mice, Nude; Neoplasm Transplantation; Papilloma; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured; Urethane | 1991 |
Active oxygen transforms murine myeloid progenitor cells in vitro.
Topics: Animals; Cell Count; Cell Division; Cell Line; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Granulocytes; Hematopoietic Stem Cells; Hot Temperature; Hydrogen Peroxide; Interleukin-3; Male; Mice; Mice, Inbred DBA; Neoplasm Transplantation; Oxygen; Peroxides; Sodium Fluoride; tert-Butylhydroperoxide; Tetradecanoylphorbol Acetate; Vitamin K | 1991 |
Transformation of mouse skin endothelial cells in vivo by direct application of plasmid DNA encoding the human T24 H-ras oncogene.
Topics: Animals; Base Sequence; Blotting, Southern; Cell Transformation, Neoplastic; Cloning, Molecular; Electrophoresis, Polyacrylamide Gel; Genes, ras; Humans; Mice; Mice, Inbred Strains; Molecular Sequence Data; Neoplasms, Experimental; Plasmids; Polymerase Chain Reaction; Precipitin Tests; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1991 |
Hepatic peroxisome proliferators induce morphologic transformation of Syrian hamster embryo cells, but not peroxisomal beta oxidation.
Topics: 2,4-Dichlorophenoxyacetic Acid; 2,4,5-Trichlorophenoxyacetic Acid; Animals; Cell Transformation, Neoplastic; Cells, Cultured; Clofibrate; Cricetinae; Diethylhexyl Phthalate; Digitonin; Embryo, Mammalian; Fatty Alcohols; Hypolipidemic Agents; Liver; Mesocricetus; Microbodies; Nicotinic Acids; Rats; Tetradecanoylphorbol Acetate | 1991 |
Elevation of AP1 activity during F9 cell differentiation is due to increased c-jun transcription.
Topics: Base Sequence; Cell Differentiation; Cell Transformation, Neoplastic; Colforsin; Cyclic AMP; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; Genetic Markers; Humans; Molecular Sequence Data; Multigene Family; Proto-Oncogene Proteins c-jun; RNA, Messenger; Stem Cells; Tetradecanoylphorbol Acetate; Transcription Factors; Transcription, Genetic; Tretinoin; Tumor Cells, Cultured | 1990 |
Downregulation of the early genomic growth factor response in neu oncogene-transformed cells.
Topics: Animals; Cell Line, Transformed; Cell Transformation, Neoplastic; Chimera; Down-Regulation; ErbB Receptors; Gene Expression; Growth Substances; Immunohistochemistry; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); Receptor, ErbB-2; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection | 1990 |
Intermolecular association of the p185neu protein and EGF receptor modulates EGF receptor function.
Topics: Animals; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cross-Linking Reagents; DNA Replication; Down-Regulation; Epidermal Growth Factor; ErbB Receptors; Fibroblasts; Gene Expression; Kinetics; Macromolecular Substances; Mice; Molecular Weight; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogenes; Receptor, ErbB-2; Tetradecanoylphorbol Acetate; Thymidine | 1990 |
Effects of quercetin, a plant flavonol, on the two-stage transformation in vitro.
Topics: Animals; Antineoplastic Agents; Cell Transformation, Neoplastic; Clone Cells; Dose-Response Relationship, Drug; Mice; Mice, Inbred BALB C; Quercetin; Tetradecanoylphorbol Acetate | 1990 |
Tumor-promoting phorbol ester and activated Ha-ras synergistically reduce the interleukin 3 requirement in a mast cell line.
Topics: Animals; Blotting, Northern; Cell Division; Cell Line; Cell Transformation, Neoplastic; Genes, ras; Genetic Vectors; Interleukin-3; Mast Cells; Mice; Phorbol 12,13-Dibutyrate; Protein Kinase C; Restriction Mapping; Tetradecanoylphorbol Acetate; Transfection | 1991 |
Relationship of acivicin-induced monocytoid differentiation of human myeloid leukemia cells to acivicin-induced modulation of growth factor, cytokine, and protooncogene mRNA expression.
Topics: Antibiotics, Antineoplastic; Cell Differentiation; Cell Transformation, Neoplastic; Cytokines; Gene Expression Regulation, Neoplastic; Genes, myc; Granulocyte-Macrophage Colony-Stimulating Factor; Heat-Shock Proteins; Humans; Interleukin-1; Interleukin-3; Interleukin-6; Isoxazoles; Leukemia, Myeloid; Monocytes; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myb; Proto-Oncogenes; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Necrosis Factor-alpha | 1991 |
Long-chain (sphingoid) bases inhibit multistage carcinogenesis in mouse C3H/10T1/2 cells treated with radiation and phorbol 12-myristate 13-acetate.
Topics: Animals; Biological Transport; Cell Line; Cell Transformation, Neoplastic; Gamma Rays; Kinetics; Mice; Mice, Inbred C3H; Protein Kinase C; Sphingosine; Tetradecanoylphorbol Acetate | 1991 |
Suppression of phorbol ester-enhanced radiation-induced malignancy in vitro by protease inhibitors is independent of protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cell Line; Cell Membrane; Cell Transformation, Neoplastic; Cytosol; DNA Replication; Isoquinolines; Kinetics; Mice; Mice, Inbred C3H; Piperazines; Protease Inhibitors; Protein Kinase C; Tetradecanoylphorbol Acetate; Thymidine; Time Factors; Tosylphenylalanyl Chloromethyl Ketone; X-Rays | 1991 |
Neoplastic transformation of C3H/10T1/2 cells following exposure to 120-Hz modulated 2.45-GHz microwaves and phorbol ester tumor promoter.
Topics: Animals; Cell Transformation, Neoplastic; Dose-Response Relationship, Radiation; Electromagnetic Fields; Microwaves; Tetradecanoylphorbol Acetate | 1991 |
Phorbol ester and bryostatin differentially regulate the hydrolysis of phosphatidylethanolamine in Ha-ras- and raf-oncogene-transformed NIH 3T3 cells.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Bryostatins; Cell Line; Cell Transformation, Neoplastic; Genes, ras; Guanosine 5'-O-(3-Thiotriphosphate); Hydrolysis; Kinetics; Lactones; Macrolides; Mice; Mice, Inbred Strains; Oncogene Proteins v-raf; Oncogenes; Phosphatidylethanolamines; Phospholipase D; Protein Kinase C; Protein-Tyrosine Kinases; Retroviridae Proteins, Oncogenic; Rubidium; Tetradecanoylphorbol Acetate | 1991 |
Effect of tretinoin on collagen gel contraction induced by mouse 3T3 fibroblasts.
Topics: Animals; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Collagen; Fibroblasts; Gels; Mice; Tetradecanoylphorbol Acetate; Tretinoin | 1991 |
Isolation of a gene sequence induced later by tumor-promoting 12-O-tetradecanoylphorbol-13-acetate in mouse osteoblastic cells (MC3T3-E1) and expressed constitutively in ras-transformed cells.
Topics: Amino Acid Sequence; Animals; Base Sequence; Blotting, Northern; Cell Line; Cell Transformation, Neoplastic; Cycloheximide; DNA; Gene Expression; Genes; Genes, ras; Mice; Molecular Sequence Data; Osteoblasts; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Tissue Distribution | 1990 |
Elevated expression of proto-oncogenes during interleukin-5-induced growth and differentiation of murine B lineage cells.
Topics: Animals; Cell Transformation, Neoplastic; Chronic Disease; Female; Gene Expression Regulation; Immunoglobulin M; Interleukin-5; Kinetics; Leukemia; Mice; Mice, Inbred Strains; Proto-Oncogene Proteins c-myc; Proto-Oncogenes; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Novel ATP-binding heat-inducible protein of Mr = 37,000 that is sensitive to transformation in BALB/3T3 cells.
Topics: 2,2'-Dipyridyl; Adenosine Triphosphate; Animals; Arsenic; Arsenites; Calcimycin; Carrier Proteins; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Chick Embryo; Electrophoresis, Polyacrylamide Gel; Endoplasmic Reticulum Chaperone BiP; Fibroblasts; Heat-Shock Proteins; Methionine; Mice; Mice, Inbred BALB C; Precipitin Tests; Sepharose; Sulfur Radioisotopes; Tetradecanoylphorbol Acetate; Tunicamycin | 1990 |
A Swiss 3T3 variant cell line resistant to the effects of tumor promoters cannot be transformed by src.
Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Deoxyglucose; DNA Probes; DNA Replication; Drug Resistance; Epidermal Growth Factor; Mice; Oncogene Protein pp60(v-src); Oncogenes; Plasmids; Retroviridae; Tetradecanoylphorbol Acetate; Transfection | 1990 |
Papilloma and carcinoma production in DMBA-initiated, onion oil-promoted mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Allium; Animals; Carcinoma; Cell Transformation, Neoplastic; Female; Garlic; Mice; Papilloma; Plant Oils; Plants, Medicinal; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1990 |
Evidence that weak promotion of carcinogen-initiated cells prevents their progression to malignancy.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzoflavones; Benzyl Alcohols; Cell Transformation, Neoplastic; Cortisone; Dose-Response Relationship, Drug; Indoles; Mice; Mice, Inbred BALB C; Papilloma; Precancerous Conditions; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin; Vitamin E | 1990 |
The role of the c-fms oncogene in the regulation of HL-60 cell differentiation.
Topics: Base Sequence; Calcitriol; Cell Transformation, Neoplastic; Colony-Stimulating Factors; Dimethyl Sulfoxide; Gene Expression; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Substances; Humans; Leukemia, Promyelocytic, Acute; Macrophage Colony-Stimulating Factor; Macrophages; Molecular Sequence Data; Oligonucleotides; Polymerase Chain Reaction; Proto-Oncogene Proteins; Receptor, Macrophage Colony-Stimulating Factor; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 1990 |
Inhibition of phorbol ester-induced monocytic differentiation and c-fms gene expression by dexamethasone: potential involvement of arachidonic acid metabolites.
Topics: Arachidonic Acids; Cell Transformation, Neoplastic; Dexamethasone; Gene Expression Regulation, Leukemic; Humans; Leukemia; Monocytes; Phenotype; Proto-Oncogene Proteins; Receptor, Macrophage Colony-Stimulating Factor; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Induction of differentiation in v-Ha-ras-transformed MDCK cells by prostaglandin E2 and 8-bromo-cyclic AMP is associated with a decrease in steady-state level of inositol 1,4,5-trisphosphate.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; Cyclic AMP; Diglycerides; Dinoprostone; Dogs; Genes, ras; GTP-Binding Proteins; Guanine Nucleotides; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Isoproterenol; Oncogene Protein p21(ras); Phospholipids; Tetradecanoylphorbol Acetate; Time Factors; Virulence Factors, Bordetella | 1990 |
Transcription of the transforming genes of the oncogenic human papillomavirus-16 is stimulated by tumor promotors through AP1 binding sites.
Topics: Base Sequence; Cell Line; Cell Transformation, Neoplastic; Chloramphenicol O-Acetyltransferase; DNA-Binding Proteins; Genes, Viral; HeLa Cells; Humans; Molecular Sequence Data; Oligonucleotide Probes; Papillomaviridae; Plasmids; Promoter Regions, Genetic; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-jun; Tetradecanoylphorbol Acetate; Transcription Factors; Transcription, Genetic; Transfection | 1990 |
Adenovirus E1A represses protease gene expression and inhibits metastasis of human tumor cells.
Topics: Adenovirus Early Proteins; Base Sequence; Cell Transformation, Neoplastic; Chloramphenicol O-Acetyltransferase; DNA-Binding Proteins; Gene Expression; Humans; Metalloendopeptidases; Microbial Collagenase; Molecular Sequence Data; Neoplasm Invasiveness; Neoplasm Metastasis; Oncogene Proteins, Viral; Peptide Hydrolases; Proto-Oncogene Proteins c-jun; Proto-Oncogenes; Tetradecanoylphorbol Acetate; Transcription Factors; Transcription, Genetic; Transfection | 1990 |
Persistent induction of cyclooxygenase in p60v-src-transformed 3T3 fibroblasts.
Topics: Animals; Avian Sarcoma Viruses; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Dexamethasone; Enzyme Induction; Kinetics; Methionine; Mice; Mutation; Oncogene Protein pp60(v-src); Platelet-Derived Growth Factor; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Protein-Tyrosine Kinases; Temperature; Tetradecanoylphorbol Acetate | 1990 |
Increased erythroid potentiating activity/tissue inhibitor of metalloproteinases and jun/fos transcription factor complex characterize tumor promoter-induced megakaryoblastic differentiation of K562 leukemia cells.
Topics: Cell Line; Cell Transformation, Neoplastic; DNA-Binding Proteins; Gene Expression; Glycoproteins; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Lymphokines; Microbial Collagenase; Protein Biosynthesis; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; RNA, Messenger; Tetradecanoylphorbol Acetate; Tissue Inhibitor of Metalloproteinases; Transcription Factors | 1990 |
Mononuclear phagocytes and HSV-1 infection: increased permissivity in differentiated U937 cells is mediated by post-transcriptional regulation of viral immediate-early gene expression.
Topics: Cell Line; Cell Transformation, Neoplastic; Dihydroxycholecalciferols; Gene Expression Regulation, Viral; Genes, Regulator; Genes, Viral; Herpes Simplex; Humans; Leukemia, Myelomonocytic, Acute; Phagocytes; RNA, Viral; Simplexvirus; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1990 |
BK virus early RNA transcripts in stably transformed cells: enhanced levels induced by dibutyryl cyclic AMP, forskolin and 12-O-tetradecanoylphorbol-13-acetate treatment.
Topics: Animals; Base Sequence; BK Virus; Blotting, Southern; Bucladesine; Cell Line; Cell Transformation, Neoplastic; Colforsin; Cricetinae; DNA, Single-Stranded; DNA, Viral; Genes, Viral; Molecular Sequence Data; Nucleic Acid Hybridization; Oligonucleotide Probes; Polymerase Chain Reaction; Polyomavirus; RNA, Viral; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1990 |
Cultured Reed-Sternberg cells HDLM-1 and KM-H2 can be induced to become histiocytelike cells. H-RS cells are not derived from lymphocytes.
Topics: Adult; Antigens, Differentiation; Antigens, Neoplasm; Arachidonic Acids; Biological Factors; Cell Transformation, Neoplastic; Cytokines; Extracellular Matrix; Gene Rearrangement; Histiocytes; Hodgkin Disease; Humans; Ki-1 Antigen; Lymphocytes; Male; Phagocytosis; Phenotype; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1990 |
Loss of bradykinin receptors and TPA-stimulated Na+ influx in SV40-transformed WI-38 cells.
Topics: Amiloride; Bradykinin; Cell Division; Cell Line; Cell Transformation, Neoplastic; Growth Substances; Humans; Inositol Phosphates; Kinetics; Receptors, Bradykinin; Receptors, Neurotransmitter; Simian virus 40; Sodium; Tetradecanoylphorbol Acetate | 1990 |
Expression of the chloramphenicol acetyltransferase (CAT) reporter gene by the murine Cyp1a-2 (cytochrome P3(450)) promoter in hepatoma cell cultures.
Topics: Animals; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Chloramphenicol O-Acetyltransferase; Cytochrome P-450 Enzyme System; Gene Expression Regulation, Enzymologic; Mice; Mice, Inbred C57BL; Plasmids; Promoter Regions, Genetic; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Herpes simplex virus type-1-induced stimulation of ribosomal protein S6 phosphorylation is inhibited in neomycin-treated human epidermoid carcinoma 2 cells and in ras-transformed cells.
Topics: Animals; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Genes, ras; Herpes Simplex; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Neomycin; Phosphatidylinositols; Phosphorylation; Protein Kinase C; Rats; Ribosomal Protein S6; Ribosomal Proteins; Simplexvirus; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Identification of a serum-inducible messenger RNA (5B10) as the mouse homologue of calcyclin: tissue distribution and expression in metastatic, ras-transformed NIH 3T3 cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Amino Acid Sequence; Animals; Base Sequence; Calcium-Binding Proteins; Cell Cycle Proteins; Cell Division; Cell Line, Transformed; Cell Transformation, Neoplastic; Cell Transformation, Viral; Chick Embryo; Fibroblasts; Gene Expression Regulation; Mice; Mice, Nude; Molecular Sequence Data; Neoplasm Metastasis; Neoplasm Proteins; Neoplasm Transplantation; Oncogene Protein p21(ras); Organ Specificity; S100 Calcium Binding Protein A6; S100 Proteins; Simian virus 40; Species Specificity; Tetradecanoylphorbol Acetate | 1990 |
Potentiation of oncogenic N-ras-induced neurite outgrowth and ornithine decarboxylase activity by phorbol dibutyrate and protein kinase inhibitor H-8.
Topics: Animals; Cell Differentiation; Cell Transformation, Neoplastic; Colforsin; Dexamethasone; Epidermal Growth Factor; Isoquinolines; Nerve Growth Factors; Neurons; Oncogene Protein p21(ras); Ornithine Decarboxylase; Phorbol 12,13-Dibutyrate; Protein Kinase C; Protein Kinase Inhibitors; Rats; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1990 |
Establishment of a highly reproducible transformation assay of a ras-transfected BALB 3T3 clone by treatment with promoters.
Topics: Animals; Carcinogenicity Tests; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Clone Cells; Cocarcinogenesis; Fibroblasts; Mice; Mice, Inbred BALB C; Oncogene Protein p21(ras); Tetradecanoylphorbol Acetate | 1990 |
A RAS oncogene imparts growth factor independence to myeloid cells that abnormally regulate protein kinase C: a nonautocrine transformation pathway.
Topics: Cell Division; Cell Line; Cell Transformation, Neoplastic; Down-Regulation; Drug Resistance; Enzyme Activation; Gene Expression; Genes, ras; Genetic Vectors; Granulocytes; Humans; Interleukin-3; Mutation; Neomycin; Protein Kinase C; Tetradecanoylphorbol Acetate; Transfection | 1990 |
Analysis of nuclear sugar-binding components in undifferentiated and in vitro differentiated human promyelocytic leukemia cells (HL60).
Topics: Carrier Proteins; Cell Differentiation; Cell Nucleus; Cell Transformation, Neoplastic; Dimethyl Sulfoxide; DNA; Fluorescein; Fluoresceins; Humans; Lectins; Leukemia, Promyelocytic, Acute; Microscopy, Fluorescence; Nuclear Proteins; Phenotype; Receptors, Cell Surface; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Initiating activity of 3-tert-butyl-4-hydroxyanisole (3-BHA) and its metabolites in two-stage transformation of BALB/3T3 cells.
Topics: Animals; Benzoquinones; Butylated Hydroxyanisole; Carcinogenicity Tests; Cell Transformation, Neoplastic; Cells, Cultured; Dimethyl Sulfoxide; Mice; Tetradecanoylphorbol Acetate | 1990 |
Myeloid leukemia differentiation by phorbol ester and retinoic acid: a practical approach.
Topics: Cell Transformation, Neoplastic; Diagnosis, Differential; Humans; Leukemia, Erythroblastic, Acute; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid; Leukemia, Promyelocytic, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tetradecanoylphorbol Acetate; Tretinoin | 1990 |
Studies of the rad-equivalence of ethylene oxide in the presence and absence of 12-O-tetradecanoylphorbol-13-acetate (TPA) in C3H/10T1/2 cells.
Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Culture Media; Ethylene Oxide; Fibroblasts; Gamma Rays; Linear Models; Mice; Radiation Dosage; Tetradecanoylphorbol Acetate; Time Factors | 1990 |
v-Ha-ras transgene abrogates the initiation step in mouse skin tumorigenesis: effects of phorbol esters and retinoic acid.
Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Genes, ras; Keratinocytes; Mice; Mice, Inbred Strains; Mice, Transgenic; Plasmids; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin | 1990 |
Characterization of epidermal growth factor receptor induction by retinoic acid in a chemically transformed rat liver cell line.
Topics: Animals; Blotting, Northern; Cell Line; Cell Transformation, Neoplastic; Cycloheximide; Epidermal Growth Factor; Epithelial Cells; ErbB Receptors; Gene Expression; In Vitro Techniques; Methylnitronitrosoguanidine; Precipitin Tests; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Tretinoin | 1990 |
Regulation of the relative abundances of c-myc mRNAs in human promyelocytic HL60 cells.
Topics: Cell Transformation, Neoplastic; Dimethyl Sulfoxide; Gene Expression Regulation, Neoplastic; Humans; Leukemia, Promyelocytic, Acute; Promoter Regions, Genetic; Proto-Oncogene Proteins c-myc; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 1990 |
Induction of differentiation of the human histiocytic lymphoma cell line U937 in the absence of vimentin expression.
Topics: Calcitriol; Cell Transformation, Neoplastic; Fluorescent Antibody Technique; Gene Expression Regulation, Neoplastic; Humans; Immunoblotting; Intermediate Filaments; Lymphoma, Large B-Cell, Diffuse; Phagocytosis; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured; Vimentin | 1990 |
In vitro establishment and characterization of a human megakaryoblastic cell line.
Topics: Blotting, Northern; Bone Marrow; Bone Marrow Cells; Cell Differentiation; Cell Line; Cell Nucleus; Cell Transformation, Neoplastic; Humans; Karyotyping; Leukemia, Megakaryoblastic, Acute; Megakaryocytes; Microscopy, Electron; Tetradecanoylphorbol Acetate | 1990 |
Inhibition of 12-O-tetradecanoylphorbol-13-acetate-enhanced transformation in vitro by inhibitors of phospholipid metabolism.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Cocarcinogenesis; Dose-Response Relationship, Drug; Drug Antagonism; Hydrocortisone; Methylcholanthrene; Mice; Mice, Inbred BALB C; Phospholipids; Tetradecanoylphorbol Acetate | 1990 |
Effects of activators and inhibitors of protein kinase C on two-stage transformation in BALB/3T3 cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Cell Line; Cell Transformation, Neoplastic; Cocarcinogenesis; Diglycerides; Drug Antagonism; Enzyme Activation; Glycerides; Isoquinolines; Methylcholanthrene; Mice; Palmitoylcarnitine; Piperazines; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate | 1990 |
Cellular F-actin levels as a marker for cellular transformation: relationship to cell division and differentiation.
Topics: Actins; Biomarkers, Tumor; Cell Differentiation; Cell Division; Cell Line; Cell Transformation, Neoplastic; Dimethyl Sulfoxide; Flow Cytometry; Humans; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1990 |
The non-phorbol ester tumor promoter okadaic acid does not promote morphological transformation or inhibit junctional communication in hamster embryo cells.
Topics: Animals; Carcinogens; Cell Communication; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Embryo, Mammalian; Ethers, Cyclic; Intercellular Junctions; Mesocricetus; Okadaic Acid; Tetradecanoylphorbol Acetate | 1990 |
Study of various transforming effects of the anabolic agents trenbolone and testosterone on Syrian hamster embryo cells.
Topics: Animals; Benzo(a)pyrene; Cell Line; Cell Line, Transformed; Cell Transformation, Neoplastic; Cricetinae; Estrenes; Testosterone; Tetradecanoylphorbol Acetate; Trenbolone Acetate | 1990 |
Effect of 12-O-tetradecanoylphorbol-13-acetate on colony formation and intercellular communication in a coculture system of JB6 clones.
Topics: Animals; Cell Aggregation; Cell Communication; Cell Division; Cell Line; Cell Transformation, Neoplastic; Clone Cells; Epidermis; Fluorescent Dyes; Isoquinolines; Kinetics; Mice; Tetradecanoylphorbol Acetate | 1990 |
A host-mediated in vivo/in vitro assay with peritoneal murine macrophages for the detection of carcinogenic chemicals.
Topics: 1-Naphthylamine; Animals; Carcinogenicity Tests; Carcinogens; Cell Transformation, Neoplastic; Drug Evaluation, Preclinical; Macrophages; Male; Mice; Peritoneal Cavity; Phenytoin; Tetradecanoylphorbol Acetate | 1990 |
ras oncogene activation of a VL30 transcriptional element is linked to transformation.
Topics: Animals; Base Sequence; Cell Transformation, Neoplastic; DNA Mutational Analysis; Gene Expression Regulation; Genes, ras; Mice; Molecular Sequence Data; Nuclear Proteins; Oncogene Protein p21(ras); Regulatory Sequences, Nucleic Acid; Repetitive Sequences, Nucleic Acid; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factors | 1990 |
Inhibition of radiation-induced transformation of C3H/10T1/2 cells by specific protease substrates.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Mice; Oligopeptides; Peptide Hydrolases; Protease Inhibitors; Tetradecanoylphorbol Acetate | 1990 |
Induction of the expression of differentiation-related antigens on human colon carcinoma cells by stimulating protein kinase C.
Topics: Antibodies, Monoclonal; Antigens, Differentiation; Antigens, Neoplasm; Autoradiography; Carcinoma; Cell Line; Cell Transformation, Neoplastic; Colonic Neoplasms; Flow Cytometry; Fluorescent Antibody Technique; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Immunoenzyme Techniques; Microscopy, Electron; Protein Kinase C; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Responses of human cervical keratinocytes in vitro to tumour promoters and diethylstilboestrol.
Topics: Carcinogens; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Cervix Uteri; Clone Cells; Diethylstilbestrol; Diterpenes; Female; Humans; Keratins; Kinetics; Phorbols; Terpenes; Tetradecanoylphorbol Acetate | 1985 |
Class II histocompatibility antigen expression in human melanocytes transformed by Harvey murine sarcoma virus (Ha-MSV) and Kirsten MSV retroviruses.
Topics: Cell Division; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Harvey murine sarcoma virus; Histocompatibility Antigens Class II; Humans; Interferon-gamma; Kirsten murine sarcoma virus; Melanocytes; Melanoma; Oncogenes; RNA; Tetradecanoylphorbol Acetate | 1986 |
Multistage transformation of cultured rat urothelium: the effects of N-methyl-N-nitrosourea, sodium saccharin, sodium cyclamate and 12-O-tetradecanoylphorbol-13-acetate.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Cocarcinogenesis; Cyclamates; Epithelium; Female; Hyperplasia; Methylnitrosourea; Phenotype; Rats; Rats, Inbred F344; Saccharin; Tetradecanoylphorbol Acetate; Urinary Bladder | 1986 |
Degradation and biosynthesis of the glucose transporter protein in chicken embryo fibroblasts transformed by the src oncogene.
Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Chick Embryo; Culture Media; Fibroblasts; Genes; Kinetics; Monosaccharide Transport Proteins; Oncogenes; Phosphorylation; Protein Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins pp60(c-src); Tetradecanoylphorbol Acetate; Vanadates; Vanadium | 1987 |
Phospholipase C mimics the differential effects of phorbol-12-myristate-13-acetate on the colony formation and cornification of cultured normal and transformed human keratinocytes.
Topics: Cell Transformation, Neoplastic; Cells, Cultured; Epidermal Cells; Epidermis; Humans; Keratins; Kinetics; Skin; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1987 |
Effect of 5-azacytidine on malignant transformation of a mutant derived from the mouse BALB/c 3T3 cell line resistant to transformation by chemical carcinogens.
Topics: 4-Nitroquinoline-1-oxide; Animals; Azacitidine; Benzo(a)pyrene; Cell Line; Cell Transformation, Neoplastic; DNA; Epidermal Growth Factor; Metallothionein; Methylation; Methylnitronitrosoguanidine; Mice; Mice, Inbred BALB C; Mutation; Proto-Oncogenes; Tetradecanoylphorbol Acetate | 1987 |
Role of second messengers in regulating the growth-associated S6 protein kinase activity.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Avian Sarcoma Viruses; Bucladesine; Calcimycin; Cell Transformation, Neoplastic; Chick Embryo; Cyclic AMP; Fibroblasts; Inositol Phosphates; Kinetics; Phosphorylation; Protein Kinases; Proto-Oncogenes; Tetradecanoylphorbol Acetate | 1987 |
Transcriptional control of high molecular weight keratin gene expression in multistage mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Animals, Newborn; Carcinoma; Cell Transformation, Neoplastic; Female; Gene Expression Regulation; Genes; Keratins; Mice; Mice, Inbred Strains; Nucleic Acid Hybridization; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1988 |
Carbachol-induced reverse transformation of Chinese hamster ovary cells transfected with and expressing the m5 muscarinic acetylcholine receptor.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Carbachol; Cell Line; Cell Transformation, Neoplastic; Cholecystokinin; Cricetinae; Cyclic AMP; Dinoprostone; Female; Kinetics; Ovary; Receptors, Muscarinic; Tetradecanoylphorbol Acetate; Transfection | 1989 |
Mitogenic activity of phorbol esters and insulin-like growth factor 1 in chemically transformed mouse fibroblasts BP-A31: independent effects and differential sensitivity to inhibition by 3-isobutyl-1-methyl xanthine.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Blotting, Northern; Cell Division; Cell Transformation, Neoplastic; Colforsin; Cyclic AMP; Cycloheximide; Epidermal Growth Factor; Gene Expression Regulation; Insulin; Insulin-Like Growth Factor I; Mice; Platelet-Derived Growth Factor; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Somatomedins; Suramin; Tetradecanoylphorbol Acetate; Theophylline | 1989 |
Mutation of amino acids in pp60c-src that are phosphorylated by protein kinases C and A.
Topics: Amino Acids; Animals; Cell Transformation, Neoplastic; DNA Mutational Analysis; Gene Expression Regulation; Mice; Mutation; Phosphorylation; Plasmids; Protein Kinase C; Protein Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins pp60(c-src); Serine; Tetradecanoylphorbol Acetate | 1989 |
Germ line c-myc is not down-regulated by loss or exclusion of activating factors in myc-induced macrophage tumors.
Topics: Animals; Base Sequence; Bucladesine; Cell Transformation, Neoplastic; Chromatin; Colony-Stimulating Factors; Deoxyribonuclease I; DNA; Exons; Gene Expression Regulation; Humans; Macrophages; Methylation; Mice; Molecular Sequence Data; Oncogenes; RNA; Sequence Homology, Nucleic Acid; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1989 |
Modulation of ornithine decarboxylase gene transcript levels by differentiation inducers in human promyelocytic leukemia HL60 cells.
Topics: Bucladesine; Calcitriol; Cell Line; Cell Transformation, Neoplastic; Dimethyl Sulfoxide; Gene Expression; Humans; Leukemia, Promyelocytic, Acute; Ornithine Decarboxylase; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myc; RNA; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tretinoin | 1989 |
Malignant conversion of UV radiation and chemically induced mouse skin benign tumors by free-radical-generating compounds.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Amidines; Animals; Benzoyl Peroxide; Carcinogens; Cell Transformation, Neoplastic; Female; Free Radicals; Mice; Mice, Hairless; Mice, Inbred Strains; Neoplasms, Radiation-Induced; Papilloma; Peroxides; Skin; Skin Diseases; Skin Neoplasms; tert-Butylhydroperoxide; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 1989 |
Reduced induction of c-fos but not of c-myc expressions in a nontumorigenic revertant R1 of Ej-ras-transformed NIH/3T3 cells treated with 12-O-tetradecanoylphorbol-13-acetate (TPA).
Topics: Animals; Cell Line, Transformed; Cell Transformation, Neoplastic; Fibroblasts; Gene Expression Regulation, Neoplastic; Humans; Mice; Phenotype; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-myc; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1989 |
Consistent oncogene methylation changes in epithelial cells chemically transformed in vitro.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Base Sequence; Benzo(a)pyrene; Blotting, Southern; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; DNA; Epithelial Cells; Epithelium; Genes, ras; Male; Methylation; Proto-Oncogenes; Rats; Rats, Inbred F344; Restriction Mapping; Tetradecanoylphorbol Acetate; Trachea | 1989 |
[Inhibitory effect of green tea extract on promotion and related action of TPA].
Topics: Animals; Antioxidants; Catechin; Cell Transformation, Neoplastic; Edema; Female; Mice; Mice, Inbred BALB C; Ornithine Decarboxylase; Sister Chromatid Exchange; Tea; Tetradecanoylphorbol Acetate | 1989 |
AP1/jun function is differentially induced in promotion-sensitive and resistant JB6 cells.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Chloramphenicol O-Acetyltransferase; Cloning, Molecular; DNA-Binding Proteins; Epidermal Growth Factor; Epidermis; Gene Expression Regulation; Genetic Variation; Kinetics; Mice; Nucleic Acid Hybridization; Plasmids; Promoter Regions, Genetic; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-jun; Simplexvirus; Tetradecanoylphorbol Acetate; Transcription Factors; Transfection | 1989 |
Loss of responsiveness of an AP1-related factor, PEBP1, to 12-O-tetradecanoylphorbol-13-acetate after transformation of NIH 3T3 cells by the Ha-ras oncogene.
Topics: Animals; Binding Sites; Cell Transformation, Neoplastic; Chromatography; DNA-Binding Proteins; Enhancer Elements, Genetic; Genes, ras; Mice; Phosphoric Monoester Hydrolases; Phosphorylation; Protein Kinase C; Proto-Oncogene Proteins c-jun; Tetradecanoylphorbol Acetate; Transcription Factors | 1989 |
Enhancement of the invasive ability of a transformed human bronchial epithelial cell line by 12-O-tetradecanoyl-phorbol-13-acetate and diacylglycerol.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Chemotaxis; Diglycerides; Epithelium; Glycerides; Humans; Lung; Mice; Mice, Nude; Microbial Collagenase; Neoplasm Invasiveness; Neoplasm Transplantation; Rats; Tetradecanoylphorbol Acetate; Trachea; Transplantation, Heterologous | 1989 |
Activation of the cellular Harvey ras gene in mouse skin tumors initiated with urethane.
Topics: Animals; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cocarcinogenesis; Codon; DNA Probes; Gene Amplification; Genes, ras; Mice; Mutation; Papilloma; Polymorphism, Restriction Fragment Length; Proto-Oncogene Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Stem Cell Assay; Urethane | 1989 |
Multistage-promotion and carcinogenesis studies in rat tracheal epithelial cells in culture.
Topics: Aneuploidy; Animals; Cell Transformation, Neoplastic; Cells, Cultured; DNA; Keratins; Methylnitronitrosoguanidine; Rats; Rats, Inbred F344; Tetradecanoylphorbol Acetate; Tracheal Neoplasms | 1985 |
Cytoplasmic domains determine signal specificity, cellular routing characteristics and influence ligand binding of epidermal growth factor and insulin receptors.
Topics: Animals; Binding Sites; Cell Division; Cell Line; Cell Membrane; Cell Transformation, Neoplastic; Chimera; Cytoplasm; DNA; ErbB Receptors; Fibroblasts; Gene Expression Regulation; Humans; Ligands; Mice; Phosphorylation; Receptor, Insulin; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection | 1989 |
Detection of distinct transforming genes in X-ray induced tumors.
Topics: Animals; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cells, Cultured; Cocarcinogenesis; Mice; Mice, Inbred Strains; Neoplasms, Radiation-Induced; Oncogenes; Papilloma; Restriction Mapping; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transfection; X-Rays | 1989 |
Effect of tea on 12-O tetradecanoyl-phorbol-13 acetate (TPA) induced promotion of transformation in JB6 mouse epidermal cells.
Topics: Animals; Antioxidants; Cell Line, Transformed; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Mice; Tea; Tetradecanoylphorbol Acetate | 1989 |
Calcium-independent growth of human ovarian carcinoma cells.
Topics: Animals; Calcium; Calmodulin; Carcinoma; Cell Line; Cell Transformation, Neoplastic; Cricetinae; Cricetulus; Culture Media; Dose-Response Relationship, Drug; Female; Humans; Ovarian Neoplasms; Ovary; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
Tumor promotion and depletion of protein kinase C in epidermal JB6 cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Cell Division; Cell Line; Cell Transformation, Neoplastic; Enzyme Activation; Epidermis; Immunoblotting; Isoquinolines; Peptide Fragments; Piperazines; Protein Kinase C; Tetradecanoylphorbol Acetate | 1989 |
Regulation of ornithine decarboxylase gene expression in normal and transformed hamster embryo fibroblasts following stimulation by 12-O-tetradecanoylphorbol-13-acetate.
Topics: Animals; Blotting, Northern; Blotting, Southern; Cell Transformation, Neoplastic; Cricetinae; Cycloheximide; Dactinomycin; Gene Expression Regulation; Ornithine Decarboxylase; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myc; RNA, Messenger; Tetradecanoylphorbol Acetate | 1989 |
Effects of triiodothyronine and tamoxifen on cell transformation induced by an activated c-Ha-ras oncogene.
Topics: Animals; Blotting, Southern; Cell Line; Cell Transformation, Neoplastic; Clone Cells; DNA; Genes, ras; Tamoxifen; Tetradecanoylphorbol Acetate; Transfection; Triiodothyronine | 1989 |
Characterization of the human cell line TE671.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Cerebellar Neoplasms; DNA, Neoplasm; Gene Expression Regulation; Genes, ras; Humans; Karyotyping; Medulloblastoma; Mice; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1989 |
Similar and synergistic inhibition of gap-junctional communication by ras transformation and tumor promoter treatment of mouse primary keratinocytes.
Topics: Animals; Cell Communication; Cell Differentiation; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Epidermal Cells; Fibroblasts; Genes, ras; Mice; Mice, Inbred BALB C; Tetradecanoylphorbol Acetate | 1989 |
Transformation stimulates glucose transporter gene expression in the absence of protein kinase C.
Topics: Animals; Brain; Cell Line; Cell Transformation, Neoplastic; Gene Expression Regulation; Genes, ras; Humans; Kinetics; Monosaccharide Transport Proteins; Oncogenes; Protein Kinase C; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1989 |
Flat reversion by okadaic acid of raf and ret-II transformants.
Topics: Animals; Blotting, Northern; Blotting, Western; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Ethers, Cyclic; Fibronectins; Fluorescent Antibody Technique; Genes, ras; Ionophores; Kinetics; Mice; Okadaic Acid; Oncogenes; Proto-Oncogenes; Tetradecanoylphorbol Acetate; Transfection | 1989 |
The phospholipid- and calcium-dependent protein kinase as a target in tumor chemotherapy.
Topics: Animals; Antineoplastic Agents; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Dexamethasone; Genes, ras; Kinetics; Mice; Phosphorylation; Protein Kinase C; Ribosomal Protein S6; Ribosomal Proteins; Tetradecanoylphorbol Acetate; Transfection | 1989 |
2,3,7,8-Tetrachlorodibenzo-p-dioxin enhancement of N-methyl-N'-nitro-N-nitrosoguanidine-induced transformation of rat tracheal epithelial cells in culture.
Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Dioxins; Dose-Response Relationship, Drug; Epithelium; Male; Methylnitronitrosoguanidine; Polychlorinated Dibenzodioxins; Rats; Rats, Inbred F344; Tetradecanoylphorbol Acetate; Trachea | 1989 |
Osteopontin, a transformation-associated cell adhesion phosphoprotein, is induced by 12-O-tetradecanoylphorbol 13-acetate in mouse epidermis.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cell Adhesion; Cell Transformation, Neoplastic; DNA; Epidermis; Female; Mice; Molecular Sequence Data; Osteopontin; Phosphoproteins; Protein Biosynthesis; Protein Processing, Post-Translational; Sequence Homology, Nucleic Acid; Sialoglycoproteins; Tetradecanoylphorbol Acetate | 1989 |
Enhanced jun gene expression is an early genomic response to transforming growth factor beta stimulation.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Gene Expression Regulation; Humans; Proto-Oncogene Mas; Proto-Oncogenes; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription Factors; Transfection; Transforming Growth Factors | 1989 |
[Changes in the morphology of fibroblasts of different degrees of transformation under the action of 12-tetradecanoylphorbol-13-acetate].
Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Embryo, Mammalian; Fibroblasts; Mice; Mice, Inbred BALB C; Mice, Inbred CBA; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
Promoter-enhanced neoplastic transformation after gamma-ray exposure at 10 cGy/day.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Cobalt Radioisotopes; Gamma Rays; Mice; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1989 |
Continuous-wave ultrasound and neoplastic transformation in vitro.
Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Cocarcinogenesis; Fibroblasts; Mice; Mice, Inbred C3H; Neoplasms, Radiation-Induced; Tetradecanoylphorbol Acetate; Ultrasonics | 1989 |
[Cell adhesion in rat fibroblasts: effect of tumor promoters].
Topics: Animals; Bee Venoms; Cell Adhesion; Cell Transformation, Neoplastic; Cells, Cultured; Fibroblasts; Melitten; Rats; Tetradecanoylphorbol Acetate | 1989 |
Response of neoplasms of B cell lineage to the proliferative effects of B cell growth factor and the phorbol ester TPA.
Topics: B-Lymphocytes; Cell Division; Cell Transformation, Neoplastic; DNA; Humans; Interleukin-4; Interleukins; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma; Lymphoma, Non-Hodgkin; Palatine Tonsil; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tetradecanoylphorbol Acetate | 1989 |
Regulation of transforming growth factor alpha messenger RNA expression in a chemically transformed rat hepatic epithelial cell line by phorbol ester and hormones.
Topics: Animals; Cell Transformation, Neoplastic; Cycloheximide; Epidermal Growth Factor; ErbB Receptors; Gene Expression Regulation; Hormones; In Vitro Techniques; Liver; Protein Kinase C; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Transcription, Genetic; Transforming Growth Factors | 1989 |
The effect of 12-O-tetradecanoylphorbol-13-acetate (TPA) on leukemic cells from chronic B cell leukemia.
Topics: B-Lymphocytes; Cell Adhesion; Cell Differentiation; Cell Transformation, Neoplastic; Histocytochemistry; Humans; Leukemia, Hairy Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Tetradecanoylphorbol Acetate | 1989 |
Tumorigenic conversion of xeroderma pigmentosum lymphoblastoid cells without karyotypic alteration.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Humans; Karyotyping; Lymphocyte Transfusion; Lymphocytes; Mice; Mice, Inbred BALB C; Mice, Nude; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Tumor Stem Cell Assay; Ultraviolet Rays; Xeroderma Pigmentosum | 1989 |
Improvement of carcinogen identification in BALB/3T3 cell transformation by application of a 2-stage method.
Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Methylnitronitrosoguanidine; Mice; Mice, Inbred BALB C; Mutagens; Tetradecanoylphorbol Acetate | 1989 |
Differential expression of an 80-kDa protein kinase C substrate in preneoplastic and neoplastic mouse JB6 cells.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Mice; Mice, Inbred BALB C; Neoplasm Proteins; Neoplasms, Experimental; Phosphorylation; Precancerous Conditions; Protein Kinase C; Substrate Specificity; Tetradecanoylphorbol Acetate | 1989 |
Tumour initiatory activity of a herbicide diuron on mouse skin.
Topics: Animals; Cell Transformation, Neoplastic; Diuron; Dose-Response Relationship, Drug; Drug Synergism; Mice; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1989 |
Early superoxide dismutase-sensitive event promotes neoplastic transformation in mouse epidermal JB6 cells.
Topics: Animals; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Glutathione Peroxidase; Mice; Superoxide Dismutase; Superoxides; Tetradecanoylphorbol Acetate | 1988 |
Effect of diterpene esters on actin cytoskeleton of SV40-transformed keratinocytes is not reproduced by diacylglycerols.
Topics: Actins; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cytoskeleton; Diglycerides; Diterpenes; Esters; Glycerides; Humans; Simian virus 40; Tetradecanoylphorbol Acetate | 1988 |
Characterization of the transformation properties of Shope fibroma virus.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cocarcinogenesis; DNA, Viral; Fibroblasts; Fibroma Virus, Rabbit; Mice; Neoplasms, Experimental; Poxviridae; Rabbits; Tetradecanoylphorbol Acetate; Transfection; Ultraviolet Rays | 1988 |
Proto-oncogene fos: factors affecting expression and covalent modification of the gene product.
Topics: Animals; Blood Physiological Phenomena; Cattle; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Fibroblasts; Gene Expression Regulation; Gene Products, gag; Phosphorylation; Protein Kinases; Protein Processing, Post-Translational; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogenes; Rats; Retroviridae Proteins; Sarcoma Viruses, Murine; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1987 |
Vasopressin, phorbol diesters and serum elicit choline glycerophospholipid hydrolysis and diacylglycerol formation in nontransformed cells: transformed derivatives do not respond.
Topics: Animals; Blood; Cell Line; Cell Transformation, Neoplastic; Culture Media; Diglycerides; Embryo, Mammalian; Glycerides; Kinetics; Phorbol Esters; Phosphatidylcholines; Rats; Simian virus 40; Tetradecanoylphorbol Acetate; Vasopressins | 1988 |
Phospholipid-sensitive, Ca2+-dependent protein kinase activity in rat embryo fibroblasts transformed by herpes simplex virus type 2.
Topics: Animals; Cell Transformation, Neoplastic; Cell Transformation, Viral; Embryo, Mammalian; Enzyme Induction; Fibroblasts; Neoplasm Proteins; Protein Kinase C; Rats; Rats, Inbred BUF; Simplexvirus; Tetradecanoylphorbol Acetate | 1988 |
Colony-stimulating factor 1-mediated regulation of a chimeric c-fms/v-fms receptor containing the v-fms-encoded tyrosine kinase domain.
Topics: Animals; Cell Transformation, Neoplastic; Cloning, Molecular; Colony-Stimulating Factors; DNA; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogenes; Rats; Receptors, Cell Surface; Receptors, Colony-Stimulating Factor; Tetradecanoylphorbol Acetate | 1988 |
Induction of foci of morphologically transformed cells in synchronized populations of 10T1/2 cells by N-methyl-N'-nitro-N-nitrosoguanidine and the effect of spontaneous transformation on calculated transformation frequency.
Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Methylnitronitrosoguanidine; Mice; Mutation; Proto-Oncogenes; Sodium-Potassium-Exchanging ATPase; Tetradecanoylphorbol Acetate | 1988 |
Differences in transferrin receptor function between normal developing and transformed myogenic cells as revealed by differential effects of phorbol ester on receptor distribution and rates of iron uptake.
Topics: Animals; Avian Sarcoma Viruses; Biological Transport; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; Conalbumin; DNA Replication; Iron; Kinetics; Muscles; Phorbols; Receptors, Transferrin; Tetradecanoylphorbol Acetate | 1988 |
Use of the orthogonal design method to study the synergistic effects of asbestos fibres and 12-O-tetradecanoylphorbol-13-acetate (TPA) in the BALB/3T3 cell transformation system.
Topics: Animals; Asbestos; Asbestos, Crocidolite; Asbestos, Serpentine; Cell Transformation, Neoplastic; Cells, Cultured; Dose-Response Relationship, Drug; Drug Synergism; Mice; Mice, Inbred BALB C; Mutagenicity Tests; Mutagens; Tetradecanoylphorbol Acetate | 1988 |
Tyrosine phosphorylation in signal transduction.
Topics: 1-Phosphatidylinositol 4-Kinase; Animals; Cell Transformation, Neoplastic; Cells, Cultured; Gene Expression Regulation; Immunoblotting; Mice; Mice, Inbred Strains; Peptide Mapping; Phosphorylation; Phosphotransferases; Platelet-Derived Growth Factor; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogenes; Signal Transduction; Tetradecanoylphorbol Acetate; Tyrosine | 1988 |
Polyoma middle T abrogates TPA requirement of murine melanocytes and induces malignant melanoma.
Topics: Animals; Antigens, Polyomavirus Transforming; Blotting, Northern; Blotting, Western; Cell Line; Cell Transformation, Neoplastic; Melanocytes; Melanoma, Experimental; Mice; Polyomavirus; Protein Kinase C; Proto-Oncogenes; Tetradecanoylphorbol Acetate; Transfection | 1988 |
Promotion-like enhancement of transformed phenotypes in human endometrial stromal cells.
Topics: Cell Transformation, Neoplastic; Cells, Cultured; Diethylstilbestrol; Endometrium; Female; gamma-Glutamyltransferase; Humans; L-Lactate Dehydrogenase; Methylnitronitrosoguanidine; Phenotype; Tetradecanoylphorbol Acetate | 1985 |
Inhibition of epidermal terminal differentiation and tumour promotion by retinoids.
Topics: Acyltransferases; Animals; Antineoplastic Agents; Cell Differentiation; Cell Transformation, Neoplastic; Cells, Cultured; Enzyme Induction; Epidermis; Growth Inhibitors; Mice; Mice, Inbred BALB C; Retinoids; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transglutaminases | 1985 |
Effects of retinoic acid on the transformation and metabolic cooperation of rat liver cells in vitro, and on the growth of hepatoma cells in vivo.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Drug Synergism; gamma-Glutamyltransferase; Liver; Liver Neoplasms, Experimental; Rats; Rats, Inbred F344; Tetradecanoylphorbol Acetate; Tretinoin | 1986 |
Transformation studies on human fibroblasts from familial polyposis coli patients and normal donors.
Topics: Adenomatous Polyposis Coli; Cell Division; Cell Transformation, Neoplastic; Fibroblasts; Humans; Kinetics; Methylnitronitrosoguanidine; Multiple Endocrine Neoplasia; Neoplasms; Skin; Tetradecanoylphorbol Acetate | 1988 |
Effect of X-ray dose protraction and a tumor promoter on transformation induction in vitro.
Topics: Animals; Carcinogens; Cell Line; Cell Survival; Cell Transformation, Neoplastic; In Vitro Techniques; Mice; Tetradecanoylphorbol Acetate; Time Factors | 1988 |
Effect of growth state, tumor promoters, and transformation upon intercellular communication between C3H/10T1/2 murine fibroblasts.
Topics: Animals; Carcinogens; Cell Communication; Cell Line; Cell Transformation, Neoplastic; Isoquinolines; Methylcholanthrene; Methylnitronitrosoguanidine; Mice; Polychlorinated Dibenzodioxins; Tetradecanoylphorbol Acetate | 1989 |
Regulation of collagen VI expression in fibroblasts. Effects of cell density, cell-matrix interactions, and chemical transformation.
Topics: Actins; Animals; Blotting, Northern; Cell Count; Cell Line; Cell Transformation, Neoplastic; Collagen; Disulfides; DNA Probes; Fibronectins; Gene Expression Regulation; Guanidine; Guanidines; Humans; Mice; Nucleic Acid Hybridization; RNA, Messenger; Tetradecanoylphorbol Acetate | 1989 |
Induction of neoplastic transformation in C3H/10T1/2 cells by 2.45-GHz microwaves and phorbol ester.
Topics: Animals; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Microwaves; Tetradecanoylphorbol Acetate | 1989 |
Induction of integrated adenovirus E1A and E1B genes in transformed human cells by phorbol ester tumor promoters.
Topics: Adenovirus Early Proteins; Adenoviruses, Human; Cell Line; Cell Transformation, Neoplastic; Cloning, Molecular; Cycloheximide; DNA; Genes; Genes, Viral; Humans; KB Cells; Kinetics; Oncogene Proteins, Viral; Phorbol Esters; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1987 |
Myeloid antigen expression on common acute lymphatic leukaemia blasts after culture.
Topics: Adult; Antigens, Differentiation; Antigens, Differentiation, Myelomonocytic; Antigens, Neoplasm; Cell Transformation, Neoplastic; Child; Child, Preschool; Humans; Infant; Middle Aged; Neprilysin; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1988 |
Conditional immortalization and/or transformation of rat cells carrying v-abl or EJras oncogene in the presence or absence of glucocorticoid hormone.
Topics: Adenovirus Early Proteins; Animals; Cell Transformation, Neoplastic; Cells, Cultured; DNA; Genes, ras; Glucocorticoids; Oncogene Proteins, Viral; Oncogenes; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate; Transfection | 1988 |
Role of reactive oxygen in tumor promotion: implication of superoxide anion in promotion of neoplastic transformation in JB-6 cells by TPA.
Topics: Animals; Antioxidants; Arachidonic Acid; Arachidonic Acids; Cell Line; Cell Transformation, Neoplastic; Cocarcinogenesis; Hydroxides; Hydroxyl Radical; Lipoxygenase Inhibitors; Mannitol; Mice; Phorbols; Skin Neoplasms; Superoxide Dismutase; Superoxides; Tetradecanoylphorbol Acetate | 1985 |
A transforming activity not detected by DNA transfer to NIH 3T3 cells is detected by JB6 mouse epidermal cells.
Topics: Animals; Cell Adhesion; Cell Line; Cell Transformation, Neoplastic; Contact Inhibition; DNA; DNA Restriction Enzymes; Epidermal Cells; Mice; Phenotype; Tetradecanoylphorbol Acetate; Transfection | 1985 |
Caffeine and other phosphodiesterase inhibitors are potent inhibitors of the promotional effect of TPA on morphological transformation of hamster embryo cells.
Topics: Adenylyl Cyclases; Animals; Bucladesine; Caffeine; Cell Communication; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Cyclic AMP; Mesocricetus; Phorbols; Phosphodiesterase Inhibitors; Tetradecanoylphorbol Acetate | 1985 |
Are free radicals involved in tumor promotion?
Topics: Animals; Antioxidants; Butylated Hydroxyanisole; Cell Transformation, Neoplastic; Cytochrome c Group; Dose-Response Relationship, Drug; Free Radicals; Hydrogen Peroxide; Nitroblue Tetrazolium; Superoxides; Tetradecanoylphorbol Acetate; Time Factors | 1985 |
Site-specific increased phosphorylation of pp60v-src after treatment of RSV-transformed cells with a tumor promoter.
Topics: Animals; Arvicolinae; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Dimethyl Sulfoxide; ErbB Receptors; Mice; Mice, Inbred BALB C; Oncogene Protein pp60(v-src); Phorbol Esters; Phosphorylation; Protein Kinase C; Protein Kinases; Receptors, Cell Surface; Sarcoma, Avian; Tetradecanoylphorbol Acetate; Viral Proteins | 1985 |
Ribosomal protein S6 phosphorylation and morphological changes in response to the tumour promoter 12-O-tetradecanoylphorbol 13-acetate in primary human tumour cells, established and transformed cell lines.
Topics: Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Fibroblasts; Glioma; Humans; Meningeal Neoplasms; Meningioma; Neoplasms; Phosphorylation; Ribosomal Proteins; Simian virus 40; Tetradecanoylphorbol Acetate | 1985 |
The extracellular matrix of normal chick embryo fibroblasts: its effect on transformed chick fibroblasts and its proteolytic degradation by the transformants.
Topics: Animals; Avian Sarcoma Viruses; Cell Fractionation; Cell Transformation, Neoplastic; Cells, Cultured; Chick Embryo; Extracellular Matrix; Fibroblasts; Kinetics; Microscopy, Electron; Molecular Weight; Plasminogen; Tetradecanoylphorbol Acetate | 1985 |
Regulation of cell differentiation and tumor promotion by 1 alpha,25 dihydroxyvitamin D3.
Topics: Animals; Calcitriol; Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; Cricetinae; Enzyme Induction; Humans; Lymphocytes; Melanins; Melanoma; Mice; Ornithine Decarboxylase; Protein Kinase C; Receptors, Calcitriol; Receptors, Steroid; Skin; Tetradecanoylphorbol Acetate | 1985 |
Differential effects of the tumor promoter phorbol-12-myristate-13-acetate on the morphological and biochemical differentiation of N-18 mouse neuroblastoma cells.
Topics: Acetylcholinesterase; Animals; Axons; Bucladesine; Carrier Proteins; Cell Transformation, Neoplastic; Cells, Cultured; Cyclic AMP Receptor Protein; Fetal Blood; Growth Inhibitors; Mice; Neuroblastoma; Phorbols; Tetradecanoylphorbol Acetate | 1985 |
Tumor promoters in conjunction with calcium ionophores mimic antigenic stimulation by reactivation of alloantigen-primed murine T lymphocytes.
Topics: Animals; Calcimycin; Carcinogens; Cell Transformation, Neoplastic; Clone Cells; Cyclic AMP; Cyclosporins; Cytotoxicity, Immunologic; Drug Synergism; Egtazic Acid; Female; Immunosuppressive Agents; Interleukin-2; Isoantigens; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Protein Kinase C; Rats; Rats, Inbred Lew; Receptors, Immunologic; Receptors, Interleukin-2; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1985 |
Enhancement by 1 alpha,25-dihydroxyvitamin D3 of chemically induced transformation of BALB 3T3 cells without induction of ornithine decarboxylase or activation of protein kinase C1.
Topics: Animals; Caenorhabditis elegans Proteins; Calcitriol; Carrier Proteins; Cell Line; Cell Survival; Cell Transformation, Neoplastic; DNA; Drug Synergism; Enzyme Activation; Enzyme Induction; Epidermal Growth Factor; ErbB Receptors; Methylcholanthrene; Mice; Ornithine Decarboxylase; Protein Kinase C; Receptors, Cell Surface; Receptors, Drug; Receptors, Immunologic; Tetradecanoylphorbol Acetate | 1986 |
Differential effects of phorbol ester on the beta-adrenergic response of normal and ras-transformed NIH3T3 cells.
Topics: Animals; Base Sequence; Cell Line; Cell Transformation, Neoplastic; Cyclic AMP; DNA, Neoplasm; Fibroblasts; Humans; Isoproterenol; Mice; Mice, Nude; Oncogenes; Phenotype; Phorbols; Receptors, Adrenergic, beta; Tetradecanoylphorbol Acetate; Urinary Bladder Neoplasms | 1985 |
Cloning and characterization of putative genes that specify sensitivity to neoplastic transformation by tumor promoters.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cell Transformation, Neoplastic; Cloning, Molecular; DNA Restriction Enzymes; Genes; Haplorhini; Humans; Mice; Mice, Inbred BALB C; Nucleic Acid Hybridization; Oncogenes; Phenotype; Plasmids; Tetradecanoylphorbol Acetate | 1986 |
12-O-Tetradecanoylphorbol-13-acetate (TPA)-induced gene sequences in human primary diploid fibroblasts and their expression in SV40-transformed fibroblasts.
Topics: Bloom Syndrome; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; DNA; Fibroblasts; Gene Expression Regulation; Humans; Phorbols; RNA, Messenger; Simian virus 40; Tetradecanoylphorbol Acetate; Xeroderma Pigmentosum | 1985 |
Effect of phorbol esters on the activity of purified transforming growth factors.
Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Drug Synergism; Epidermal Growth Factor; ErbB Receptors; Kidney; Peptides; Phorbols; Rats; Receptors, Cell Surface; Tetradecanoylphorbol Acetate; Transforming Growth Factors | 1986 |
The oncogene of BAV-3 as a mutagen.
Topics: Adenoviridae; Animals; Cattle; Cell Transformation, Neoplastic; Cricetinae; Cricetulus; Deoxyribonuclease EcoRI; DNA Restriction Enzymes; DNA, Viral; Drug Resistance; Mercaptopurine; Mesocricetus; Mutation; Oncogenes; Plasmids; Tetradecanoylphorbol Acetate | 1985 |
Enhanced protein phosphorylation of carcinogen-initiated 10T1/2 cells accompanies their neoplastic transformation.
Topics: Animals; Calcium; Cell Transformation, Neoplastic; Cells, Cultured; Culture Media; Diterpenes; ErbB Receptors; Mice; Molecular Weight; Phosphates; Phosphoproteins; Phosphorylation; Proteins; Receptors, Cell Surface; Retinyl Esters; Tetradecanoylphorbol Acetate; Vitamin A | 1986 |
Induction of an unusual type of shared phosphorylation in human and avian cells by tumor-promoting phorbol esters or transformation.
Topics: Amino Acids; Animals; Avian Sarcoma Viruses; Cell Transformation, Neoplastic; Cells, Cultured; Chick Embryo; Diglycerides; Fibroblasts; Humans; Molecular Weight; Peptide Mapping; Phosphorylation; Protein Kinase C; Proteins; Tetradecanoylphorbol Acetate | 1986 |
Induction of anchorage-independent growth of JB6 mouse epidermal cells by 1 alpha,25-dihydroxyvitamin D3.
Topics: Animals; Calcitriol; Carcinogens; Cell Adhesion; Cell Cycle; Cell Line; Cell Transformation, Neoplastic; DNA; DNA Replication; DNA-Binding Proteins; Epidermal Cells; Mice; Receptors, Calcitriol; Receptors, Steroid; Tetradecanoylphorbol Acetate; Tretinoin | 1986 |
Coordinate regulation of myelomonocytic phenotype by v-myb and v-myc.
Topics: Animals; Avian Leukosis Virus; Avian Myeloblastosis Virus; Avian Sarcoma Viruses; Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; Chick Embryo; Genes, Viral; Oncogenes; Phenotype; Tetradecanoylphorbol Acetate | 1986 |
Inhibition of biological actions of 12-O-tetradecanoylphorbol-13-acetate by inhibitors of protein kinase C.
Topics: Animals; Cell Communication; Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; Diglycerides; Mice; Palmitoylcarnitine; Phloretin; Protein Kinase C; Superoxides; Tetradecanoylphorbol Acetate | 1986 |
Differential response to retinoic acid of Syrian hamster embryo fibroblasts expressing v-src or v-Ha-ras oncogenes.
Topics: Animals; Avian Sarcoma Viruses; Cell Division; Cell Line; Cell Transformation, Neoplastic; Embryo, Mammalian; Fibroblasts; Genes; Genes, Viral; Guinea Pigs; Kinetics; Oncogene Protein p21(ras); Oncogene Protein pp60(v-src); Oncogene Proteins, Viral; Oncogenes; Ornithine Decarboxylase; Retroviridae Proteins; Tetradecanoylphorbol Acetate; Tretinoin | 1986 |
Defects of cyclic adenosine 3':5'-monophosphate-dependent protein kinases in initiated clones derived from BALB/c 3T3 mouse fibroblasts.
Topics: 4-Nitroquinoline-1-oxide; Animals; Cell Division; Cell Line; Cell Transformation, Neoplastic; Clone Cells; Cyclic AMP; Ethyl Methanesulfonate; Fibroblasts; Methylnitronitrosoguanidine; Mice; Mice, Inbred BALB C; Protein Kinases; Tetradecanoylphorbol Acetate | 1987 |
DNA sequences in human nasopharyngeal carcinoma cells that specify susceptibility to tumor promoter-induced neoplastic transformation.
Topics: Animals; Base Sequence; Cell Line; Cell Transformation, Neoplastic; DNA; DNA Restriction Enzymes; DNA, Neoplasm; Herpesvirus 4, Human; Humans; Mice; Nasopharyngeal Neoplasms; Tetradecanoylphorbol Acetate; Transfection | 1987 |
Coordinate regulation of stromelysin and collagenase genes determined with cDNA probes.
Topics: Animals; Cell Transformation, Neoplastic; Cloning, Molecular; DNA; DNA Restriction Enzymes; Endopeptidases; Genes; Genes, Regulator; Matrix Metalloproteinase 3; Microbial Collagenase; Nucleic Acid Hybridization; Protein Biosynthesis; Rabbits; Synovial Fluid; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1987 |
Inhibition of 12-O-tetradecanoylphorbol-13-acetate-enhanced transformation in vitro by radical scavengers.
Topics: Animals; Catalase; Cell Transformation, Neoplastic; Free Radicals; Hydrogen Peroxide; Mannitol; Mice; Mice, Inbred BALB C; Superoxide Dismutase; Superoxides; Tetradecanoylphorbol Acetate | 1987 |
'Water structure' versus 'radical scavenger' theories as explanations for the suppressive effects of DMSO and related compounds on radiation-induced transformation in vitro.
Topics: Acetamides; Cell Transformation, Neoplastic; Cells, Cultured; Dimethyl Sulfoxide; Dimethylformamide; Dose-Response Relationship, Drug; Hydroxides; Hydroxyl Radical; Neoplasms, Radiation-Induced; Tetradecanoylphorbol Acetate; Water | 1987 |
Effect of phorbol myristate acetate on cultured tumor cells derived from different stages of avian sarcoma virus (ASV)-induced neoplastic growth.
Topics: Animals; Avian Sarcoma Viruses; Cell Transformation, Neoplastic; Chick Embryo; Chickens; Fibroblasts; Oncogene Protein pp60(v-src); Protein Kinases; Retroviridae Proteins; Sarcoma, Avian; Sarcoma, Experimental; Tetradecanoylphorbol Acetate | 1987 |
[Reversal of malignant transformation induced by the oncogenic virus SV40. I. Induction of reversal to normal type for the contact inhibition trait].
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Contact Inhibition; Cricetinae; Cricetulus; Mutation; Phenotype; Simian virus 40; Tetradecanoylphorbol Acetate | 1987 |
Partial down-regulation of protein kinase C in C3H 10T 1/2 mouse fibroblasts transfected with the human Ha-ras oncogene.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Fibroblasts; Genes, ras; Humans; Isoenzymes; Mice; Protein Kinase C; Tetradecanoylphorbol Acetate; Transfection | 1988 |
Sodium fluoride promotes morphological transformation of Syrian hamster embryo cells.
Topics: Animals; Benzo(a)pyrene; Cell Transformation, Neoplastic; Cells, Cultured; Cocarcinogenesis; Fluorides; Genes, ras; Phenotype; Phosphates; Sodium Fluoride; Tetradecanoylphorbol Acetate | 1988 |
Modified responsiveness of v-Ha-ras-transfected rat fibroblasts to growth factors and a tumor promoter.
Topics: Animals; Blotting, Northern; Bombesin; Carcinogenicity Tests; Carcinogens; Cell Adhesion; Cell Transformation, Neoplastic; Cells, Cultured; Epidermal Growth Factor; Fibroblasts; Mice; Mice, Nude; Oncogenes; Phenotype; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); Rats; Tetradecanoylphorbol Acetate; Transfection | 1988 |
Extracellular calcium requirement for promotion of transformation in JB6 cells.
Topics: Animals; Calcimycin; Calcium; Cell Line; Cell Transformation, Neoplastic; Egtazic Acid; Extracellular Space; Lanthanum; Mice; Nifedipine; Phorbols; Tetradecanoylphorbol Acetate | 1986 |
Retinoic acid enhancement of an early step in the transformation of mouse epidermal cells in vitro.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Cell Line; Cell Transformation, Neoplastic; Cocarcinogenesis; Dose-Response Relationship, Drug; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin | 1986 |
Effects of 12-O-tetradecanoylphorbol-13-acetate on carcinogen-induced mouse mammary lesions in organ culture.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Differentiation; Cell Transformation, Neoplastic; Drug Synergism; Female; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Organ Culture Techniques; Tetradecanoylphorbol Acetate | 1986 |
Altered expression of oncogenes in mouse epidermis following exposure to benzo(a)pyrene diol epoxides.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Cell Transformation, Neoplastic; Dihydroxydihydrobenzopyrenes; DNA, Neoplasm; Female; Mice; Mice, Inbred Strains; Nucleic Acid Hybridization; Oncogenes; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1986 |
Possible involvement of a lanthanide-sensitive protein kinase C substrate in lanthanide promotion of neoplastic transformation.
Topics: Calcimycin; Calcium Channel Blockers; Cell Line; Cell Transformation, Neoplastic; Enzyme Activation; ErbB Receptors; Metals, Rare Earth; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate | 1986 |
Oncogene-induced transformation of a rat embryo fibroblast cell line is enhanced by tumor promoters.
Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Fibroblasts; Lyngbya Toxins; Mice; Oncogenes; Rats; Tetradecanoylphorbol Acetate; Transfection | 1986 |
Effect of retinoic acid and phorbol-12-myristate-13-acetate on glycosyltransferase activities in normal and transformed cells.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Clone Cells; Cricetinae; Galactosyltransferases; Kinetics; Retroviridae; Sialyltransferases; Tetradecanoylphorbol Acetate; Tretinoin | 1987 |
Skin tumor promotion is associated with increased type V collagen content in the dermis.
Topics: Animals; Calcimycin; Cell Transformation, Neoplastic; Collagen; Epidermis; Female; Mice; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1987 |
Elevated levels of glucose transport and transporter messenger RNA are induced by ras or src oncogenes.
Topics: Animals; Cell Division; Cell Membrane; Cell Transformation, Neoplastic; Deoxyglucose; Gene Expression Regulation; Glucose; GTP-Binding Proteins; Monosaccharide Transport Proteins; Oncogenes; Protein-Tyrosine Kinases; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate; Transfection | 1987 |
The lack of PDGE-stimulated PGE2 release from ras-transformed NIH-3T3 cells results from reduced phospholipase C but not phospholipase A2 activity.
Topics: Animals; Calcimycin; Cell Transformation, Neoplastic; Cells, Cultured; Dinoprostone; Kinetics; Mice; Mice, Inbred Strains; Oncogenes; Phospholipases; Phospholipases A; Phospholipases A2; Platelet-Derived Growth Factor; Prostaglandins E; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1987 |
Pleiotropic effects of quercetin on the transformation of BALB 3T3 cells.
Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Depression, Chemical; Flavonoids; In Vitro Techniques; Methylcholanthrene; Mice; Quercetin; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1987 |
Differentiating among proposed mechanisms for tumor promotion in mouse skin with the use of the multievent model for cancer.
Topics: 4-Nitroquinoline-1-oxide; Acetone; Animals; Cell Transformation, Neoplastic; Mathematics; Mice; Models, Biological; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Urethane | 1987 |
Rapid phosphorylation of a specific 33-kDa protein (p33) associated with growth stimulated by murine and rat IL3 in different IL3-dependent cell lines, and its constitutive expression in a malignant independent clone.
Topics: Adenosine Triphosphate; Animals; Calcimycin; Cell Division; Cell Line; Cell Transformation, Neoplastic; Clone Cells; Concanavalin A; Culture Media; Interleukin-3; Interleukin-4; Interleukins; Kinetics; Mice; Molecular Weight; Phosphoproteins; Phosphorylation; Protein Kinase C; Rats; Recombinant Proteins; Spleen; Tetradecanoylphorbol Acetate | 1988 |
Clinical application of phorbol diester-induced leukemic cell differentiation for the definite diagnosis of acute leukemias.
Topics: Acute Disease; Adolescent; Adult; Cell Differentiation; Cell Transformation, Neoplastic; Diagnosis, Differential; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Middle Aged; Tetradecanoylphorbol Acetate | 1988 |
Proto-oncogene fos expression and post-translational modification.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Fibroblasts; Gene Expression Regulation; Gene Products, gag; Mice; Phosphorylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogenes; Recombinant Fusion Proteins; Retroviridae Proteins; Tetradecanoylphorbol Acetate | 1988 |
Comparison of mouse pro-1 and pro-2 transfectants for responses to tumor promoters and antipromoters.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Diethylhexyl Phthalate; Egtazic Acid; Epidermal Growth Factor; Mice; Mice, Inbred BALB C; Protein Kinase C; Tetradecanoylphorbol Acetate; Transfection | 1988 |
Isolation and characterization of ras-transfected BALB/3T3 clone showing morphological transformation by 12-O-tetradecanoyl-phorbol-13-acetate.
Topics: Animals; Cell Division; Cell Transformation, Neoplastic; Clone Cells; DNA; Genes, ras; Mice; Nucleic Acid Hybridization; Plasmids; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1988 |
Tumor promoter 12-O-tetradecanoylphorbol-13-acetate receptors in normal human transitional epithelial cells.
Topics: Caenorhabditis elegans Proteins; Carrier Proteins; Cell Transformation, Neoplastic; Cells, Cultured; Epithelium; Humans; Phorbols; Protein Kinase C; Protein Kinases; Receptors, Drug; Receptors, Immunologic; Tetradecanoylphorbol Acetate; Tritium; Ureter | 1985 |
Genes and signal transduction in tumor promotion: conclusions from studies with promoter resistant variants of JB-6 mouse epidermal cells.
Topics: Animals; Arginine Vasopressin; Carcinogens; Carcinoma, Bronchogenic; Cell Line; Cell Transformation, Neoplastic; Cocarcinogenesis; Heat-Shock Proteins; Mice; Oncogenes; Oxidation-Reduction; Phosphatidylinositols; Protein Kinase C; Protein Kinases; Skin Neoplasms; Stress, Physiological; Tetradecanoylphorbol Acetate; Transduction, Genetic | 1985 |
Enhanced expression of transforming growth factor beta during megakaryoblastic differentiation of K562 leukemia cells.
Topics: Cell Line; Cell Transformation, Neoplastic; Cycloheximide; Humans; Leukemia, Erythroblastic, Acute; Leukemia, Megakaryoblastic, Acute; Neoplasm Proteins; Peptide Biosynthesis; Peptides; Platelet-Derived Growth Factor; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Transforming Growth Factors; Tumor Cells, Cultured | 1988 |
Phorbol ester receptors and the induction of differentiation in the human T lymphoblastic cell line MOLT-3.
Topics: Caenorhabditis elegans Proteins; Carrier Proteins; Cell Differentiation; Cell Line, Transformed; Cell Transformation, Neoplastic; Drug Resistance; Humans; Leukemia-Lymphoma, Adult T-Cell; Phorbol 12,13-Dibutyrate; Protein Kinase C; Receptors, Drug; Statistics as Topic; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1988 |
Four-day duration of tumor promoter exposure required to transform JB6 promotion-sensitive cells to anchorage independence.
Topics: Animals; Catalase; Cell Adhesion; Cell Line; Cell Transformation, Neoplastic; Chromatography, Affinity; Collagen; Epidermis; Hydrolases; Mice; Molecular Weight; Skin; Tetradecanoylphorbol Acetate; Time Factors | 1988 |
Nalidixic acid and oxolinic acid reversibly suppress 3-methylcholanthrene-induced cell transformation of BALB/3T3 mouse cells.
Topics: Animals; Cell Communication; Cell Transformation, Neoplastic; Cells, Cultured; Methylcholanthrene; Mice; Nalidixic Acid; Oxolinic Acid; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1988 |
Cocarcinogenic and tumor-promoting capabilities of anthralin.
Topics: Animals; Anthralin; Benzo(a)pyrene; Carcinogens; Cell Transformation, Neoplastic; Cocarcinogenesis; DNA; Dose-Response Relationship, Drug; Mice; Propiolactone; Tetradecanoylphorbol Acetate | 1988 |
Phorbol ester restores L-system amino acid transport of B lymphocytes in chronic lymphocytic leukemia.
Topics: Aminoisobutyric Acids; B-Lymphocytes; Biological Transport; Cell Transformation, Neoplastic; Cycloheximide; Humans; Leucine; Leukemia, Lymphoid; Tetradecanoylphorbol Acetate | 1988 |
Ciclosporin inhibits phorbol-ester-induced hyperplastic transformation and tumor promotion in mouse skin probably by suppression of Ca2+/calmodulin-dependent processes such as phosphorylation of elongation factor 2.
Topics: Animals; Calcium; Calmodulin; Cell Transformation, Neoplastic; Chromatography, DEAE-Cellulose; Cocarcinogenesis; Cycloheximide; Cyclosporins; Cytosol; Electrophoresis, Polyacrylamide Gel; Mice; Peptide Elongation Factor 2; Peptide Elongation Factors; Phosphorus Radioisotopes; Phosphorylation; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1988 |
Transfer by pro gene transfection of tumor promoter-sensitive phenotype to promotion-insensitive JB6 cells.
Topics: Animals; Cell Transformation, Neoplastic; Mice; Mice, Inbred BALB C; Phenotype; Tetradecanoylphorbol Acetate; Transfection | 1988 |
Rapid and reversible modulation of T4 (CD4) on monocytoid cells by phorbol myristate acetate: effect on HIV susceptibility.
Topics: Acquired Immunodeficiency Syndrome; Antigens, Differentiation; Antigens, Surface; Cell Line; Cell Transformation, Neoplastic; Humans; Immunity, Innate; Kinetics; Monocytes; Tetradecanoylphorbol Acetate | 1988 |
The transformed (initiated) human cell phenotype: study of cultured skin fibroblasts from individuals predisposed to cancer.
Topics: Actins; Cell Transformation, Neoplastic; Cells, Cultured; Fibroblasts; Humans; Kirsten murine sarcoma virus; Moloney murine sarcoma virus; Neoplasms; Phenotype; Skin; Tetradecanoylphorbol Acetate | 1988 |
Effects of glucocorticoid hormones on radiation induced and 12-O-tetradecanoylphorbol-13-acetate enhanced radiation transformation in vitro.
Topics: Cell Transformation, Neoplastic; Cells, Cultured; Cortisone; Dexamethasone; Glucocorticoids; Tetradecanoylphorbol Acetate | 1988 |
Induction by growth factors from platelets of the focus-forming transformed phenotype in carcinogen-treated C3H/10T1/2 fibroblasts.
Topics: Animals; Blood Platelets; Cell Division; Cell Line; Cell Transformation, Neoplastic; Contact Inhibition; DNA; Growth Substances; Mice; Phenotype; Platelet-Derived Growth Factor; Tetradecanoylphorbol Acetate | 1988 |
[The action mechanisms of 12-0-tetradecanoylphorbol-13-acetate (TPA) and combined effects with TPA and fibroblast growth factor on the proliferation of leukemic myeloid progenitor cells].
Topics: Bone Marrow Cells; Cell Transformation, Neoplastic; Cells, Cultured; Fibroblast Growth Factors; Hematopoiesis; Hematopoietic Stem Cells; Humans; Leukemia; Tetradecanoylphorbol Acetate | 1987 |
Effects of dietary retinyl palmitate or 13-cis-retinoic acid on the promotion of tumors in mouse skin.
Topics: Administration, Cutaneous; Animals; Cell Transformation, Neoplastic; Diet; Diterpenes; Dose-Response Relationship, Drug; Female; Isotretinoin; Mice; Papilloma; Retinyl Esters; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Tretinoin; Vitamin A | 1987 |
Special type of morphological reorganization induced by phorbol ester: reversible partition of cell into motile and stable domains.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Cytoskeleton; Fibroblasts; Microscopy, Electron; Morphogenesis; Tetradecanoylphorbol Acetate | 1987 |
Morphological and isoenzymatic differentiation of B-chronic lymphocytic leukaemia cells induced by phorbolester.
Topics: Acid Phosphatase; Aged; Antigens, Surface; B-Lymphocytes; Carboxylic Ester Hydrolases; Cell Survival; Cell Transformation, Neoplastic; Electrophoresis, Polyacrylamide Gel; Female; Hexosaminidases; Humans; In Vitro Techniques; Isoelectric Focusing; Isoenzymes; L-Lactate Dehydrogenase; Leukemia, Lymphoid; Male; Middle Aged; Tetradecanoylphorbol Acetate | 1986 |
Activation of proto-oncogene expression by growth regulatory signals.
Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Epidermal Growth Factor; Genes, Regulator; Mice; Proto-Oncogenes; Tetradecanoylphorbol Acetate | 1986 |
Control of hsp70 RNA levels in human lymphocytes.
Topics: Cell Line; Cell Transformation, Neoplastic; Genes; Heat-Shock Proteins; Humans; Oncogenes; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1987 |
Bombesin induces c-fos and c-myc expression in quiescent Swiss 3T3 cells. Comparative study with other mitogens.
Topics: Animals; Bombesin; Cell Transformation, Neoplastic; Cells, Cultured; DNA Replication; Epidermal Growth Factor; Mice; Mitogens; Platelet-Derived Growth Factor; Proto-Oncogenes; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1987 |
Lifespan extension of basal cell nevus syndrome fibroblasts by transfection with mouse pro or v-myc genes.
Topics: Adult; Basal Cell Nevus Syndrome; Carcinoma, Basal Cell; Cell Division; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; DNA; Epidermal Growth Factor; Female; Genetic Engineering; Humans; Male; Phenotype; Tetradecanoylphorbol Acetate | 1987 |
B cell stimulatory factor-1/interleukin-4 mRNA is expressed by normal and transformed mast cells.
Topics: Abelson murine leukemia virus; Animals; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Female; Growth Substances; Interleukin-3; Interleukin-4; Lymphokines; Mast Cells; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Nucleic Acid Hybridization; RNA, Messenger; Tetradecanoylphorbol Acetate | 1987 |
Effects of epidermal growth factor on transferrin receptor phosphorylation and surface expression in malignant epithelial cells.
Topics: Animals; Antibodies; Binding Sites; Carcinoma, Squamous Cell; Cell Line; Cell Transformation, Neoplastic; Epidermal Growth Factor; Epithelium; ErbB Receptors; Methionine; Phosphorylation; Receptors, Transferrin; Tetradecanoylphorbol Acetate; Vanadates | 1987 |
Colony size, cell density and nature of the tumor promoter are critical variables in expression of a transformed phenotype (focus formation) in co-cultures of UV-TDTx and C3H10T1/2 cells.
Topics: Cell Count; Cell Transformation, Neoplastic; Cells, Cultured; Clone Cells; Humans; Phenotype; Tetradecanoylphorbol Acetate; Tretinoin | 1987 |
Genes that cooperate with tumor promoters in transformation.
Topics: Animals; Base Sequence; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Genes; Humans; Protein Kinase C; Tetradecanoylphorbol Acetate; Transduction, Genetic | 1987 |
Ornithine decarboxylase activity in foetal rat brain cells and in the mouse embryo fibroblasts C3H/10T1/2 CL8 cells: differences in response to medium change and to the tumor promoter TPA.
Topics: Animals; Brain; Brain Neoplasms; Cell Line; Cell Transformation, Neoplastic; Culture Media; Embryo, Mammalian; Enzyme Induction; Fibroblasts; Methylcholanthrene; Mice; Mice, Inbred C3H; Ornithine Decarboxylase; Rats; Tetradecanoylphorbol Acetate | 1987 |
[Use of the phorbol ester differentiation test in the classification of acute leukemia].
Topics: Acute Disease; Adolescent; Adult; Cell Transformation, Neoplastic; Child; Child, Preschool; Diagnosis, Differential; Female; Humans; Infant; Leukemia; Male; Middle Aged; Tetradecanoylphorbol Acetate | 1987 |
Biological and biochemical characterization of cell lines derived from initiation-promotion transformed C3H/10T1/2 cells.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; DNA; Female; Flow Cytometry; Methylcholanthrene; Mice; Mice, Inbred C3H; Molecular Weight; Peptide Biosynthesis; Tetradecanoylphorbol Acetate | 1987 |
Possible dissociation of the phorbol ester-induced oxidant response and tumor promotion in the F1 offspring of SSIN x C57BL/6J mice.
Topics: Animals; Cell Transformation, Neoplastic; Female; Male; Mice; Mice, Inbred C57BL; Mutagenicity Tests; Oxidation-Reduction; Phorbol Esters; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1987 |
[Effect of the tumor-growth promoter 12-O-tetradecanoylphorbol-13-acetate on the proliferation of different clones of mouse tumor cells in a semiliquid medium].
Topics: Animals; Cell Transformation, Neoplastic; Clone Cells; Colchicine; Culture Media; Fibroblasts; Gene Amplification; Methylcellulose; Mice; Mice, Inbred AKR; Mice, Inbred CBA; Phorbols; Sarcoma, Experimental; Tetradecanoylphorbol Acetate | 1986 |
Use of an orthogonal design method to study two-stage chemical carcinogenesis in BALB/3T3 cells.
Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Fetal Blood; Methylnitronitrosoguanidine; Mice; Statistics as Topic; Tetradecanoylphorbol Acetate | 1986 |
Promoting effect of 12-O-tetradecanoylphorbol-13-acetate on the in vitro malignant transformation of fetal rat brain cells exposed in utero to ethylnitrosourea.
Topics: Animals; Brain Neoplasms; Cell Aggregation; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Cocarcinogenesis; Concanavalin A; Ethylnitrosourea; Female; Glial Fibrillary Acidic Protein; Maternal-Fetal Exchange; Neoplasm Transplantation; Neoplastic Stem Cells; Phorbols; Pregnancy; Rats; Tetradecanoylphorbol Acetate | 1986 |
[Regulation of tumor promotion by 1 alpha, 25-dihydroxyvitamin D3, an active form of vitamin D3].
Topics: Animals; Calcitriol; Calcium; Cell Differentiation; Cell Division; Cell Transformation, Neoplastic; Enzyme Activation; Mice; Mice, Inbred BALB C; Ornithine Decarboxylase; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1986 |
Antioxidants as antitumor promoters.
Topics: Animals; Antioxidants; Cell Transformation, Neoplastic; DNA Damage; Humans; Kinetics; Mice; Nucleoproteins; Poly Adenosine Diphosphate Ribose; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1986 |
Reversible expression of morphological transformation in C3H/10T1/2 mouse embryo cultures exposed to 12-O-tetradecanoylphorbol-13-acetate.
Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Methylnitronitrosoguanidine; Mice; Phenotype; Tetradecanoylphorbol Acetate | 1986 |
Induction of metallothionein and other mRNA species by carcinogens and tumor promoters in primary human skin fibroblasts.
Topics: Cell Transformation, Neoplastic; Cells, Cultured; Cloning, Molecular; DNA; Fibroblasts; Genes; Humans; Metallothionein; Nucleic Acid Hybridization; RNA, Messenger; Skin; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1986 |
Ultraviolet irradiation transforms C3H10T1/2 cells to a unique, suppressible phenotype.
Topics: Animals; Cell Division; Cell Line; Cell Transformation, Neoplastic; Clone Cells; Mice; Mice, Inbred C3H; Phenotype; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 1986 |
Changes in polypeptide synthesis and glycosylation in mouse embryonic fibroblast C3H/10T1/2 Cl 8 cells caused by the tumor promoter 12-O-tetradecanoylphorbol 13-acetate.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Embryo, Mammalian; Fibroblasts; Gene Expression Regulation; Glycoproteins; Mice; Mice, Inbred C3H; Neoplasm Proteins; Peptide Biosynthesis; Protein Processing, Post-Translational; Tetradecanoylphorbol Acetate | 1986 |
Retinoic acid and butylated hydroxyanisole inhibit promoter-enhanced transformation in vitro.
Topics: Butylated Hydroxyanisole; Butylated Hydroxytoluene; Cell Transformation, Neoplastic; Cells, Cultured; Methylcholanthrene; Tetradecanoylphorbol Acetate; Tretinoin | 1986 |
Modulation of benzo[a]pyrene-induced morphological transformation of Syrian hamster embryo cells by butylated hydroxytoluene and butylated hydroxyanisole.
Topics: Animals; Benzo(a)pyrene; Butylated Hydroxyanisole; Butylated Hydroxytoluene; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Mesocricetus; Tetradecanoylphorbol Acetate | 1986 |
Neoplastic transformation in the planarian: I. Cocarcinogenesis and histopathology.
Topics: Animals; Cadmium; Cadmium Compounds; Carcinogens; Cell Transformation, Neoplastic; Cocarcinogenesis; Planarians; Sulfates; Tetradecanoylphorbol Acetate; Turbellaria | 1986 |
Neoplastic transformation in the planarian: II. Ultrastructure of malignant reticuloma.
Topics: Animals; Cadmium; Cadmium Compounds; Carcinogens; Cell Transformation, Neoplastic; Cocarcinogenesis; Planarians; Sulfates; Tetradecanoylphorbol Acetate; Turbellaria | 1986 |
Alterations of intercellular communication associated with the transformation of C3H/10T1/2 cells.
Topics: Animals; Cell Communication; Cell Line; Cell Transformation, Neoplastic; Isoquinolines; Methylcholanthrene; Mice; Polychlorinated Dibenzodioxins; Tetradecanoylphorbol Acetate | 1987 |
Promotion, dose rate, and repair processes in radiation-induced neoplastic transformation.
Topics: Animals; Cell Transformation, Neoplastic; DNA Repair; Dose-Response Relationship, Radiation; Mice; Mice, Inbred C3H; Tetradecanoylphorbol Acetate | 1987 |
In vitro and in vivo activity of 12-O-3-N-dansylamino TPA.
Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Dansyl Compounds; Dose-Response Relationship, Drug; Mice; Tetradecanoylphorbol Acetate; Time Factors | 1986 |
Isolation and characterization of chemically transformed pancreatic acinar cell lines from young and old mice.
Topics: Acetylglucosamine; Aging; Animals; Cell Division; Cell Line; Cell Transformation, Neoplastic; Isoenzymes; Karyotyping; L-Lactate Dehydrogenase; Lectins; Male; Methylnitrosourea; Mice; Pancreatic Neoplasms; Phenotype; Plant Lectins; Soybean Proteins; Tetradecanoylphorbol Acetate | 1987 |
Morphological transformation in three mammalian cell systems following treatment with 6-nitrochrysene and 6-nitrobenzo[a]pyrene.
Topics: Animals; Benzopyrenes; Carcinogens; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; Chrysenes; Cricetinae; Dose-Response Relationship, Drug; Phenanthrenes; Tetradecanoylphorbol Acetate | 1987 |
Comparative effects of a complete tumor promoter, TPA, and a second-stage tumor promoter, RPA, on intercellular communication, cell differentiation and cell transformation.
Topics: Animals; Cell Communication; Cell Differentiation; Cell Transformation, Neoplastic; Cells, Cultured; Mice; Mice, Inbred BALB C; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Tetradecanoylphorbol Acetate | 1985 |
Radiobiological issues in the anomalous enhanced effect of low-dose-rate fission-spectrum neutrons: reply to Letter to the Editor by G. W. Barendsen.
Topics: Animals; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; Neutrons; Radiation Dosage; Technology, Radiologic; Tetradecanoylphorbol Acetate | 1985 |
Interaction of epidermal growth factor with initiators and complete carcinogens in the C3H10T1/2 cell culture system.
Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Cocarcinogenesis; Epidermal Growth Factor; Fibroblasts; Methylcholanthrene; Mice; Mice, Inbred C3H; Tetradecanoylphorbol Acetate; Tumor Stem Cell Assay | 1985 |
Rapid induction of the expression of proto-oncogene fos during human monocytic differentiation.
Topics: Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; Dimethyl Sulfoxide; Fluorescent Antibody Technique; Genes; Humans; Leukemia, Myeloid, Acute; Macrophages; Neoplasm Proteins; Oncogenes; Protein Biosynthesis; Proto-Oncogene Mas; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1985 |
Human acute leukemia cell line with the t(4;11) chromosomal rearrangement exhibits B lineage and monocytic characteristics.
Topics: Adult; Antigens, Differentiation, B-Lymphocyte; Antigens, Neoplasm; Antigens, Surface; B-Lymphocytes; Cell Line; Cell Transformation, Neoplastic; Chromosome Aberrations; Chromosome Disorders; Clone Cells; Female; Histocytochemistry; Humans; Immunoglobulins; Karyotyping; Leukemia; Monocytes; Tetradecanoylphorbol Acetate | 1985 |
Cyclosporin A inhibits biological effects of tumor promoting phorbol esters.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cell Transformation, Neoplastic; Chromatography, Thin Layer; Cyclosporins; Edema; Female; Mice; Phorbols; Skin; Tetradecanoylphorbol Acetate; Time Factors | 1985 |
Two-stage tumor promotion in mouse skin: an alternative interpretation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cocarcinogenesis; Croton Oil; Fluocinolone Acetonide; Mice; Mice, Inbred Strains; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tosylphenylalanyl Chloromethyl Ketone; Tretinoin | 1985 |
Partial inversion of the initiation-promotion sequence of multistage tumorigenesis in the skin of NMRI mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Diterpenes; Female; Mice; Phorbol Esters; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate; Time Factors | 1985 |
Peroxisome proliferators show tumor-promoting but no direct transforming activity in vitro.
Topics: Adipose Tissue; Animals; Carcinogens; Cell Division; Cell Transformation, Neoplastic; Clofibrate; Dose-Response Relationship, Drug; Fatty Alcohols; Hypolipidemic Agents; Mice; Microbodies; Nicotinic Acids; Tetradecanoylphorbol Acetate | 1986 |
Antagonistic action of a tumor promoter and a poly(adenosine diphosphoribose) synthesis inhibitor in radiation-induced transformation in vitro.
Topics: Animals; Benzamides; Carcinogens; Cell Transformation, Neoplastic; Clone Cells; DNA, Neoplasm; Fibroblasts; Mice; Mice, Inbred C3H; Nucleoside Diphosphate Sugars; Poly Adenosine Diphosphate Ribose; Tetradecanoylphorbol Acetate | 1986 |
[Role of cell-cell interaction in tumor promotion].
Topics: Animals; Carcinogens; Cell Communication; Cell Transformation, Neoplastic; Cricetinae; Extracellular Space; Homeostasis; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Phorbol Esters; Protein Kinase C; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1986 |
Intercellular communication capacity as a possible determinant of transformation sensitivity of BALB/c 3T3 clonal cells.
Topics: Animals; Cell Communication; Cell Transformation, Neoplastic; Clone Cells; Deoxyglucose; Drug Resistance; Methylcholanthrene; Mice; Mice, Inbred BALB C; Tetradecanoylphorbol Acetate | 1985 |
Release of fibronectin is linked to tumor promotion: response of promotable and non-promotable clones of a mouse epidermal cell line.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Clone Cells; Epidermis; Fibronectins; Mice; Phorbols; Tetradecanoylphorbol Acetate; Tretinoin | 1985 |
In vitro differentiation of human melanoma cells analyzed with monoclonal antibodies.
Topics: Antibodies, Monoclonal; Antigens, Neoplasm; Antigens, Surface; Cell Line; Cell Transformation, Neoplastic; Humans; Melanins; Melanoma; Tetradecanoylphorbol Acetate | 1985 |
Ultrastructural studies of spontaneous in vitro transformation of cultured marrow monocyte-macrophage cells from a patient with congenital hypoplastic anemia.
Topics: Anemia, Aplastic; Cell Transformation, Neoplastic; Cells, Cultured; Histocytochemistry; Humans; Macrophages; Monocytes; Phagocytosis; Tetradecanoylphorbol Acetate | 1985 |
Benzoyl peroxide promotion of transformation of JB6 mouse epidermal cells: inhibition by ganglioside GT but not retinoic acid.
Topics: Animals; Benzoyl Peroxide; Cell Line; Cell Transformation, Neoplastic; Cocarcinogenesis; Gangliosides; Mice; Peroxides; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin | 1985 |
Phagocytes as carcinogens: malignant transformation produced by human neutrophils.
Topics: Animals; Cell Transformation, Neoplastic; Humans; Mice; Mice, Inbred C3H; Mice, Nude; Neutrophils; Oxidation-Reduction; Phagocytes; Tetradecanoylphorbol Acetate | 1985 |
[TPA enhancement of the mutagenic and transforming action of bovine adenovirus type 3 on cultured mouse cells].
Topics: Adenoviridae; Animals; Cattle; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Mice; Mice, Inbred C3H; Mutation; Neoplasm Transplantation; Neoplasms, Experimental; Phorbols; Tetradecanoylphorbol Acetate | 1985 |
Contrasting responses of normal and transformed rat tracheal epithelial cells to the tumor promoter 12-O-tetradecanoylphorbol-13-acetate.
Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Epithelium; Phorbols; Rats; Tetradecanoylphorbol Acetate; Trachea | 1985 |
Heterogeneity in responses of human and rodent respiratory epithelial cells to tumor promoters in culture.
Topics: Animals; Bronchi; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; DNA; Epithelium; Humans; Phorbol Esters; Rats; Tetradecanoylphorbol Acetate; Trachea | 1985 |
Enhancement and inhibition of transformation of Syrian hamster embryo cells.
Topics: Animals; Asbestos; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; DNA; Embryo, Mammalian; Female; Lymphokines; Mesocricetus; Methylnitronitrosoguanidine; Polycyclic Compounds; Sulfur Dioxide; Tetradecanoylphorbol Acetate | 1985 |
Initiation and promotion in cultures of C3H10T1/2 mouse embryo fibroblasts.
Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Cocarcinogenesis; Embryo, Mammalian; Fibroblasts; Mice; Mice, Inbred C3H; Respiratory Tract Neoplasms; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1985 |
Tumor promotion and tumor progression.
Topics: Animals; Cell Transformation, Neoplastic; Cocarcinogenesis; Humans; Mutation; Neoplasms; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1985 |
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) promotes the transformation of C3H/10T1/2 cells.
Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Dimethyl Sulfoxide; Dioxins; Dose-Response Relationship, Drug; Methylcholanthrene; Methylnitronitrosoguanidine; Mice; Polychlorinated Dibenzodioxins; Tetradecanoylphorbol Acetate | 1985 |
Evidence for microwave carcinogenesis in vitro.
Topics: Animals; Benzo(a)pyrene; Cell Transformation, Neoplastic; Cocarcinogenesis; In Vitro Techniques; Mice; Microwaves; Tetradecanoylphorbol Acetate; X-Rays | 1985 |
Inhibition of intercellular communication and enhancement of morphological transformation of Syrian hamster embryo cells by TPA. Use of TPA-sensitive and TPA-resistant cell lines.
Topics: Animals; Cell Communication; Cell Line; Cell Transformation, Neoplastic; Cricetinae; Drug Resistance; In Vitro Techniques; Mesocricetus; Phorbols; Tetradecanoylphorbol Acetate | 1985 |
Quantitative neoplastic transformation in C3H/10T1/2 cells.
Topics: Animals; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Kinetics; Mice; Mice, Inbred C3H; Models, Biological; Probability; Tetradecanoylphorbol Acetate | 1985 |
Association of DNA strand breaks with accelerated terminal differentiation in mouse epidermal cells exposed to tumor promoters.
Topics: Animals; Benzoyl Peroxide; Cell Transformation, Neoplastic; Cells, Cultured; Dimethyl Sulfoxide; DNA, Single-Stranded; Mice; Mice, Inbred BALB C; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1985 |
12-O-Tetradecanoylphorbol-13-acetate promotion of carcinogen-treated rat liver endothelial cells.
Topics: Animals; Benzo(a)pyrene; Cell Line; Cell Transformation, Neoplastic; Cocarcinogenesis; Diethylnitrosamine; Endothelium; Liver; Methylazoxymethanol Acetate; Phorbols; Rats; Tetradecanoylphorbol Acetate | 1985 |
[Role of the oncogene in the mutagenic activity of bovine adenovirus type 3].
Topics: Adenoviridae; Animals; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Cricetinae; Cricetulus; DNA, Viral; Dose-Response Relationship, Drug; Drug Resistance; Mercaptopurine; Mice; Mice, Inbred C3H; Mutation; Oncogenes; Tetradecanoylphorbol Acetate; Time Factors; Transfection | 1985 |
The toxic response of preneoplastic rat tracheal epithelial cells to 12-O-tetradecanoylphorbol-13-acetate.
Topics: Animals; Cell Differentiation; Cell Division; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; Male; Phorbols; Rats; Tetradecanoylphorbol Acetate; Trachea | 1985 |
The conditions for the modification of radiation transformation in vitro by a tumor promoter and protease inhibitors.
Topics: Animals; Antipain; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cocarcinogenesis; Mice; Oligopeptides; Phorbols; Protease Inhibitors; Tetradecanoylphorbol Acetate; Time Factors; X-Rays | 1985 |
Mechanistic aspects of initiation and promotion in C3H/10T1/2 cells.
Topics: Animals; Cell Communication; Cell Line; Cell Transformation, Neoplastic; Cocarcinogenesis; Embryo, Mammalian; Methylcholanthrene; Methylnitronitrosoguanidine; Mice; Mice, Inbred C3H; Tetradecanoylphorbol Acetate | 1985 |
Relationship of animal cell transformation models to the study of human neoplastic cell transformation.
Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Chromosome Aberrations; Cricetinae; DNA; Humans; Mesocricetus; Models, Biological; Oncogenes; Tetradecanoylphorbol Acetate | 1985 |
Mechanisms of transformation and promotion of mouse epidermal cells.
Topics: Animals; Caenorhabditis elegans Proteins; Calcium; Carrier Proteins; Cell Differentiation; Cell Transformation, Neoplastic; Cells, Cultured; Mice; Oncogenes; Protein Kinase C; Receptors, Drug; Receptors, Immunologic; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1985 |
In vitro transformation of rat tracheal epithelial cells: a model for the study of multistage carcinogenesis.
Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Models, Biological; Rats; Retinoids; Tetradecanoylphorbol Acetate; Tracheal Neoplasms | 1985 |
Potential role of treatment artifact in the effect of cell density upon frequencies of C3H/10T1/2 cell transformation.
Topics: Animals; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Methylcholanthrene; Methylnitronitrosoguanidine; Mice; Research Design; Tetradecanoylphorbol Acetate | 1985 |
Retinoids and tumorigenesis: mechanistic considerations.
Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Fibroblasts; Humans; Mice; Neoplasms; Retinoids; Tetradecanoylphorbol Acetate; Vitamin A; Vitamin A Deficiency | 1985 |
A comparative study on neoplastic transformation of human and Syrian hamster cells.
Topics: Animals; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cricetinae; Embryo, Mammalian; Female; Fetus; Fibroblasts; Fibrosarcoma; Griseofulvin; Humans; Kinetics; Mesocricetus; Methylnitronitrosoguanidine; Pregnancy; Species Specificity; Tetradecanoylphorbol Acetate | 1985 |