tetradecanoylphorbol acetate has been researched along with Carcinoma, Thymic in 55 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (34.55) | 18.7374 |
| 1990's | 30 (54.55) | 18.2507 |
| 2000's | 4 (7.27) | 29.6817 |
| 2010's | 2 (3.64) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fukuoka, N; Harada, M; Ito, Y; Kataoka, T; Nishida, A; Shiota, H | 1 |
| Farrar, J; Hamaoka, T; Hilfiker, M; Howard, M; Johnson, B; Paul, WE; Takatsu, K | 1 |
| Farrar, JJ; Hilfiker, ML; Moore, RN | 1 |
| Kirch, ME; Miller, RA; Palladino, MA; Pearlstein, KT; Pelus, LM; Staiano-Coico, L; Stutman, O | 1 |
| Benjamin, WR; Farrar, JJ; Steeg, PS | 1 |
| Farrar, JJ; Farrar, WL; Fuller-Farrar, J; Hilfiker, ML; Simon, PL; Stadler, BM | 1 |
| Dougherty, SF; Farrar, JJ; Oppenheim, JJ; Stadler, BM | 1 |
| Anderson, WB; Cooper, HL; Kraft, AS; Sando, JJ | 1 |
| Brown, BL; Corbett, NR; Dawson, CH; Dobson, PR; Dunford, JE; Varley, CL | 1 |
| Mahon, TM; O'Neill, LA | 2 |
| Engels, P; Gruart-Gouilleux, V; Sullivan, M | 1 |
| Falk, W; Krammer, PH; Praast, G; Stoeck, M; Stricker, K; Tsukitani, Y | 1 |
| Azcona-Olivera, JI; Brooks, KH; Dong, W; Linz, JE; Pestka, JJ | 1 |
| Chen, D; Rothenberg, EV | 1 |
| Brennan, P; Mahon, TM; O'Neill, LA | 1 |
| Arai, K; Arai, N; Koyano-Nakagawa, N; Lee, HJ; Naito, Y; Nishida, J; Yokota, T | 1 |
| Moynagh, PN; O'Neill, LA; Williams, DC | 1 |
| Fu, KC; Horta, MF; Koizumi, H; Kwon, BS; Liu, CC; Youn, BS; Young, JD | 1 |
| Baniyash, M; Bronstein, N; Hsu, V; Wang, L | 1 |
| Dong, W; Marin, ML; Murtha, J; Pestka, JJ | 1 |
| Kline, K; Sanders, BG; Yu, W | 1 |
| Mahon, TM; Matthews, JS; O'Neill, LA | 1 |
| Fulwood, S; Meier, KE; Qi, C; Sansbury, HM; Wisehart-Johnson, AE | 1 |
| Matthews, JS; O'Neill, LA | 1 |
| Li, S; Pestka, JJ; Yang, GH | 1 |
| Li, S; Ouyang, Y; Pestka, JJ; Yang, GH | 1 |
| Ku, H; Meier, KE | 1 |
| Ahn, JS; Ahn, SC; Choe, YK; Kang, DO; Kim, BY; Mheen, TI; Oh, WK; Park, YM | 1 |
| Bickel, M; Cohen, RB; Iwai, Y; Pluznik, DH | 2 |
| Bouaboula, M; Casellas, P; d'Angeac, AD; Dornand, J; Favero, J; Shire, D | 1 |
| Ninomiya, C; Spiegelberg, HL | 1 |
| Brooks, JW; Chedid, M; Mizel, SB; Yoza, BK | 1 |
| Hooton, JW; Pabst, HF; Paetkau, V; Spady, DW | 1 |
| Barker, E; Baumgartel, BA; Mokyr, MB; Weiskirch, LM | 1 |
| Barcellini, W; Bonara, P; Borghi, MO; Fain, C; Meroni, PL; Nicoletti, F | 1 |
| Haystead, TA; Krebs, EG; Licciardi, KA; Meier, KE | 1 |
| Harmody, D; Longley, RE | 1 |
| D'Angeac, AD; Dornand, J; Emonds-Alt, X; Erard, F; Garcia-Sanz, JA; Jullien, P | 1 |
| Costlow, M; Essani, N; Fishman, M | 1 |
| Howe, RC; MacDonald, HR; Miescher, S; Stoeck, M; von Fliedner, V | 1 |
| Cianciolo, GJ; Dinarello, CA; Gottlieb, RA; Kleinerman, ES; Knowles, RD; Lachman, LB; Lennarz, WJ | 1 |
| Balls, M; Clothier, R; Lasek, W; Steer, S | 1 |
| Lees, R; MacDonald, HR; Pantaleo, G; Stoeck, M; Szamel, M | 1 |
| Adachi, K; Morishima, Y; Morishita, Y; Ohno, R; Saito, H; Tanimoto, M | 1 |
| Komori, S; Maeda, K; Nakashima, M; Watanabe, T | 1 |
| Fishman, M; Nycum, LM | 1 |
| Dornand, J; Gerber, M; Mani, JC; Sekkat, C | 1 |
| Arai, K; Arai, N; Hagiwara, H; Lee, F; Luh, J; Yokota, T; Zlotnik, A | 1 |
| Arora, PK; Hanna, EE; Huang, FL; Huang, KP | 1 |
| Fidelus, RK | 1 |
| Geurts van Kessel, AH; Hagemeijer, A; Schoenmaker, E; van Dongen, JJ; van Oudenaren, A; Versnel, MA; Wolvers-Tettero, IL | 1 |
| Amstad, P; Bickel, M; Evequoz, V; Mergenhagen, SE; Pluznik, DH; Tsuda, H; Wahl, SM | 1 |
| Fishman, M; Gunther, G | 1 |
55 other study(ies) available for tetradecanoylphorbol acetate and Carcinoma, Thymic
| Article | Year |
|---|---|
Eomesodermin promotes interferon-γ expression and binds to multiple conserved noncoding sequences across the Ifng locus in mouse thymoma cell lines.
Topics: Animals; Base Sequence; Cell Line, Tumor; Conserved Sequence; Humans; Interferon-gamma; Ionomycin; Mice; Promoter Regions, Genetic; T-Box Domain Proteins; Tetradecanoylphorbol Acetate; Thymoma; Thymus Neoplasms | 2016 |
Pillars article: Identification of a T cell-derived B cell growth factor distinct from interleukin 2. J. Exp. Med. 1982. 155: 914-923.
Topics: Animals; B-Lymphocytes; Cell Line, Tumor; Culture Media, Conditioned; Female; History, 20th Century; Immunoglobulin Class Switching; Immunoglobulin Isotypes; Interleukin-2; Interleukin-4; Lymphocyte Activation; Lymphocyte Cooperation; Lymphokines; Lymphopoiesis; Mice; Mice, Inbred BALB C; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymoma; Thymus Neoplasms | 2013 |
Biologic properties of chromatographically separated murine thymoma-derived Interleukin 2 and colony-stimulating factor.
Topics: Animals; Antibody Formation; Chromatography; Chromatography, Agarose; Chromatography, Gel; Colony-Stimulating Factors; Concanavalin A; Interferons; Interleukin-2; Lymphokines; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Nude; Molecular Weight; Tetradecanoylphorbol Acetate; Thymoma | 1981 |
Multiple lymphokine production by a phorbol ester-stimulated mouse thymoma: relationship to cell cycle events.
Topics: Animals; Antibodies, Monoclonal; Antigens, Neoplasm; Antigens, Surface; Cell Cycle; Flow Cytometry; Interferon-gamma; Lymphokines; Mice; Neoplasms, Experimental; Phenotype; Phorbols; Rats; Tetradecanoylphorbol Acetate; Thymoma; Thymus Neoplasms | 1983 |
Production of immune interferon by an interleukin 2-independent murine T cell line.
Topics: Animals; Cell Line; Interferon-gamma; Interleukin-2; Kinetics; Mice; Neoplasms, Experimental; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymoma; Thymus Neoplasms | 1982 |
Thymoma production of T cell growth factor (Interleukin 2).
Topics: Animals; Chromatography, Gel; Concanavalin A; Growth Substances; Interleukin-2; Lymphokines; Mice; Molecular Weight; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymoma; Thymus Neoplasms | 1980 |
Relationship of cell cycle to recovery of IL 2 activity from human mononuclear cells, human and mouse T cell lines.
Topics: Animals; Cell Cycle; Cell Line; Concanavalin A; Dose-Response Relationship, Immunologic; Humans; Interleukin-2; Lymphocyte Activation; Lymphokines; Mice; Mice, Inbred Strains; Mitogens; Phagocytes; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymoma | 1981 |
Decrease in cytosolic calcium/phospholipid-dependent protein kinase activity following phorbol ester treatment of EL4 thymoma cells.
Topics: Animals; Calcium; Cell Line; Mice; Neoplasms, Experimental; Phorbol Esters; Phorbols; Phospholipids; Protein Kinases; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Thymoma; Thymus Neoplasms | 1982 |
Activation of multiple protein kinases by interleukin-1.
Topics: Animals; Breast Neoplasms; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Dose-Response Relationship, Drug; Enzyme Activation; Female; Glycogen Synthase Kinase 3; Humans; Interleukin-1; Interleukin-4; Mice; Protein Kinases; Tetradecanoylphorbol Acetate; Thymoma; Thymus Neoplasms; Tumor Cells, Cultured | 1995 |
Studies into the effect of the tyrosine kinase inhibitor herbimycin A on NF-kappa B activation in T lymphocytes. Evidence for covalent modification of the p50 subunit.
Topics: Animals; Base Sequence; Benzoquinones; Enzyme Inhibitors; Interleukin-1; Interleukin-2; Lactams, Macrocyclic; Lymphoma, T-Cell; Mice; Molecular Sequence Data; NF-kappa B; Oligodeoxyribonucleotides; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Quinones; Rifabutin; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymoma; Thymus Neoplasms; Transcription Factor RelB; Transcription Factors; Tumor Cells, Cultured | 1995 |
Characterization of the human interleukin-5 gene promoter: involvement of octamer binding sites in the gene promoter activity.
Topics: Animals; Base Sequence; Binding Sites; Bucladesine; Calcimycin; Consensus Sequence; Gene Expression Regulation; Genes; Genes, Reporter; Humans; Interleukin-5; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Plasmids; Point Mutation; Promoter Regions, Genetic; Recombinant Fusion Proteins; Regulatory Sequences, Nucleic Acid; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymoma; Thymus Neoplasms; Transcription Factors; Transfection; Tumor Cells, Cultured | 1995 |
Activation of the mouse IL-2 gene by okadaic acid: synergy with interleukin-1.
Topics: Animals; Drug Synergism; Ethers, Cyclic; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Interleukin-1; Interleukin-2; Interleukin-6; Mice; Neoplasm Proteins; Okadaic Acid; Phosphoprotein Phosphatases; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Thymoma; Thymus Neoplasms; Tumor Cells, Cultured | 1994 |
Elevated gene expression and production of interleukins 2, 4, 5, and 6 during exposure to vomitoxin (deoxynivalenol) and cycloheximide in the EL-4 thymoma.
Topics: Clone Cells; Cycloheximide; Cytokines; Gene Expression; Interleukins; Kinetics; Leucine; Models, Biological; RNA, Messenger; Stimulation, Chemical; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymoma; Thymus Neoplasms; Trichothecenes; Tritium; Tumor Cells, Cultured | 1994 |
Interleukin 2 transcription factors as molecular targets of cAMP inhibition: delayed inhibition kinetics and combinatorial transcription roles.
Topics: Base Sequence; Binding Sites; Calcimycin; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclosporine; DNA-Binding Proteins; Gene Expression; Interleukin-2; Kinetics; NF-kappa B; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymoma; Thymus Neoplasms; Transcription Factors; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1994 |
Evidence for a redox-sensitive protein tyrosine kinase in nuclear factor kappa B activation and interleukin 2 production in EL4.NOB1 cells.
Topics: Alkaloids; Animals; Benzoquinones; Cell Line; Interleukin-1; Interleukin-2; Kinetics; Lactams, Macrocyclic; Mice; NF-kappa B; Oxidation-Reduction; Protein Kinase C; Protein-Tyrosine Kinases; Quinones; Rifabutin; Staurosporine; Tetradecanoylphorbol Acetate; Thymoma; Thymus Neoplasms; Tumor Cells, Cultured | 1993 |
cAMP activates the IL-5 promoter synergistically with phorbol ester through the signaling pathway involving protein kinase A in mouse thymoma line EL-4.
Topics: Animals; Bucladesine; Cyclic AMP-Dependent Protein Kinases; Drug Synergism; Gene Expression Regulation; Interleukin-2; Interleukin-5; Mice; Promoter Regions, Genetic; T-Lymphocytes, Helper-Inducer; Tetradecanoylphorbol Acetate; Thymoma; Transfection; Tumor Cells, Cultured | 1993 |
Interleukin-1 and phorbol myristate acetate modulate the peripheral-type benzodiazepine receptor in lymphocytes and glial cells.
Topics: Animals; Binding Sites; Cell Line; Down-Regulation; Glioma; Interleukin-1; Lymphocytes; Mice; Neuroglia; Rats; Receptors, GABA-A; Tetradecanoylphorbol Acetate; Thymoma | 1993 |
Identification of a killer cell-specific regulatory element of the mouse perforin gene: an Ets-binding site-homologous motif that interacts with Ets-related proteins.
Topics: Animals; Base Sequence; Binding Sites; Cell Line; Chloramphenicol O-Acetyltransferase; DNA-Binding Proteins; Humans; Interleukin-2; Killer Cells, Lymphokine-Activated; Killer Cells, Natural; Leukemia, T-Cell; Lymphocyte Activation; Mast-Cell Sarcoma; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Molecular Weight; Oligodeoxyribonucleotides; Perforin; Pore Forming Cytotoxic Proteins; Proto-Oncogene Protein c-ets-1; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ets; Recombinant Proteins; Regulatory Sequences, Nucleic Acid; T-Lymphocytes, Cytotoxic; Tetradecanoylphorbol Acetate; Thymoma; Thymus Neoplasms; Transcription Factors; Transfection; Tumor Cells, Cultured | 1993 |
Transcriptional regulation of the murine TCR zeta gene.
Topics: Animals; Base Sequence; CD3 Complex; Genes; Lymphocyte Activation; Lymphoma, T-Cell; Membrane Proteins; Mice; Molecular Sequence Data; Receptors, Antigen, T-Cell; Regulatory Sequences, Nucleic Acid; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymoma; Transcription, Genetic; Tumor Cells, Cultured; Up-Regulation | 1995 |
Investigation into the role of protein kinase C in IL1 and PMA signalling in EL4.NOB-1 thymoma cells.
Topics: Alkaloids; Animals; Cell Line; Cell Nucleus; Chloramphenicol O-Acetyltransferase; Enzyme Inhibitors; Interleukin-1; Interleukin-2; Kinetics; Mice; NF-kappa B; Protein Kinase C; Recombinant Proteins; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Thymoma; Thymus Neoplasms; Tumor Cells, Cultured | 1996 |
Effects of mycotoxins on cytokine production and proliferation in EL-4 thymoma cells.
Topics: Androstadienes; Animals; Aspergillus; Carcinogens; Cell Survival; Fumonisins; Fusaric Acid; Fusarium; Indoles; Interleukin-2; Interleukin-5; Lymphocyte Activation; Mice; Mycotoxins; Ochratoxins; Patulin; Penicillium; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymoma; Thymus Neoplasms; Tumor Cells, Cultured; Wortmannin; Zearalenone; Zeranol | 1996 |
Modulation of murine EL-4 thymic lymphoma cell proliferation and cytokine production by vitamin E succinate.
Topics: Animals; Cell Division; Culture Media, Conditioned; Cytokines; Gene Expression; Interleukin-2; Mice; RNA, Messenger; Tetradecanoylphorbol Acetate; Thymoma; Thymus Neoplasms; Tocopherols; Transforming Growth Factor beta; Tumor Cells, Cultured; Vitamin E | 1996 |
Staurosporine, but not Ro 31-8220, induces interleukin 2 production and synergizes with interleukin 1alpha in EL4 thymoma cells.
Topics: Animals; Cell Membrane; Cytosol; Drug Synergism; Enzyme Inhibitors; Indoles; Interleukin-1; Interleukin-2; Isoenzymes; Kinetics; Mice; NF-kappa B; Protein Kinase C; Protein Kinase C-alpha; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Thymoma; Thymus Neoplasms; Time Factors; Tumor Cells, Cultured | 1997 |
Effects of protein kinase C activators on phorbol ester-sensitive and -resistant EL4 thymoma cells.
Topics: Animals; Biological Transport; Calcium-Calmodulin-Dependent Protein Kinases; Drug Resistance, Neoplasm; Enzyme Activation; Mice; Protein Kinase C; Ribosomal Protein S6 Kinases; Tetradecanoylphorbol Acetate; Thymoma; Tumor Cells, Cultured | 1997 |
Distinct roles for p42/p44 and p38 mitogen-activated protein kinases in the induction of IL-2 by IL-1.
Topics: Amino Acid Sequence; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation; Genes, Reporter; Humans; Imidazoles; Interleukin-1; Interleukin-2; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Molecular Sequence Data; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Pyridines; Rabbits; Signal Transduction; Tetradecanoylphorbol Acetate; Thymoma; Thymus Neoplasms; Transcription Factor AP-1; Transfection; Tumor Cells, Cultured | 1999 |
Down-regulation of the endoplasmic reticulum chaperone GRP78/BiP by vomitoxin (Deoxynivalenol).
Topics: Animals; Blotting, Western; Calcimycin; Carrier Proteins; DNA Fragmentation; DNA, Complementary; Down-Regulation; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Enzyme Inhibitors; Heat-Shock Proteins; HSP40 Heat-Shock Proteins; Ionomycin; Ionophores; Mice; Molecular Chaperones; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thapsigargin; Thymoma; Trichothecenes | 2000 |
Modulation of transcription factor AP-1 activity in murine EL-4 thymoma cells by vomitoxin (deoxynivalenol).
Topics: Animals; DNA-Binding Proteins; Down-Regulation; Fos-Related Antigen-2; Ionomycin; Kinetics; Mice; Phosphorylation; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Tetradecanoylphorbol Acetate; Thymoma; Transcription Factor AP-1; Transcription Factors; Transcriptional Activation; Trichothecenes; Tumor Cells, Cultured | 2000 |
Phosphorylation of paxillin via the ERK mitogen-activated protein kinase cascade in EL4 thymoma cells.
Topics: Animals; Cell Adhesion; Cytoskeletal Proteins; Mice; Mitogen-Activated Protein Kinases; Paxillin; Phosphoproteins; Phosphorylation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymoma; Tumor Cells, Cultured | 2000 |
A tactic for screening inhibitors of interleukin-2 production.
Topics: Animals; Cell Survival; Cyclosporine; Dose-Response Relationship, Drug; Formazans; Interleukin-2; Mice; T-Lymphocytes; Tacrolimus; Tetradecanoylphorbol Acetate; Tetrazolium Salts; Thymoma; Time Factors; Tumor Cells, Cultured | 2002 |
Concanavalin A-induced granulocyte-macrophage colony-stimulating factor production in a murine T-cell line is posttranscriptionally controlled.
Topics: Animals; Concanavalin A; Dactinomycin; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Granulocyte-Macrophage Colony-Stimulating Factor; Half-Life; Mice; RNA Processing, Post-Transcriptional; RNA, Messenger; RNA, Neoplasm; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymoma; Thymus Neoplasms; Transcription, Genetic; Tumor Cells, Cultured | 1992 |
Contrasting effects of the protein kinase C inhibitor staurosporine on the interleukin-1 and phorbol ester activation pathways in the EL4-6.1 thymoma cell line.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Base Sequence; Cell Line; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Interleukin-1; Interleukin-2; Interleukin-4; Isoquinolines; Mice; Molecular Sequence Data; Piperazines; Polymerase Chain Reaction; Protein Kinase C; Receptors, Interleukin-2; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate; Thymoma; Thymus Neoplasms; Tumor Cells, Cultured | 1992 |
IL-4 and transforming growth factor-beta suppress human immunoglobulin secretion in vitro by surface IgD- B cells.
Topics: B-Lymphocytes; Humans; Immunoglobulin D; Immunoglobulin Isotypes; Immunoglobulins; Interferon-gamma; Interleukin-2; Interleukin-4; Receptors, Antigen, B-Cell; Tetradecanoylphorbol Acetate; Thymoma; Transforming Growth Factor beta | 1992 |
Activation of AP-1 by IL-1 and phorbol esters in T cells. Role of protein kinase A and protein phosphatases.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Colforsin; Cyclic AMP; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Synergism; Ethers, Cyclic; Gene Expression Regulation; Interleukin-1; Mice; Okadaic Acid; Phosphoprotein Phosphatases; Protein Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-jun; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymoma; Transcription Factors; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1991 |
Human colostrum contains an activity that inhibits the production of IL-2.
Topics: Cell Survival; Colostrum; Concanavalin A; Dose-Response Relationship, Drug; Humans; Interleukin-2; Lectins; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Lymphoma, T-Cell; Phytohemagglutinins; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymoma; Thymus Neoplasms; Transforming Growth Factor beta | 1991 |
Phorbol ester-induced enhancement in lytic activity of CD8+ splenic T cells from low-dose melphalan-treated MOPC-315-tumor bearers.
Topics: Animals; Antigens, Differentiation, T-Lymphocyte; CD8 Antigens; Cell Line; Cytotoxicity, Immunologic; Dose-Response Relationship, Drug; Drug Synergism; Female; In Vitro Techniques; Ionomycin; Lymphocyte Depletion; Melphalan; Mice; Mice, Inbred BALB C; Phagocytes; Plasmacytoma; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymoma; Time Factors | 1991 |
Identification of sequences within the murine granulocyte-macrophage colony-stimulating factor mRNA 3'-untranslated region that mediate mRNA stabilization induced by mitogen treatment of EL-4 thymoma cells.
Topics: Animals; Base Sequence; Blotting, Northern; Chloramphenicol O-Acetyltransferase; Concanavalin A; DNA, Neoplasm; Granulocyte-Macrophage Colony-Stimulating Factor; Mice; Mitogens; Molecular Sequence Data; Mutagenesis; Plasmids; Protein Biosynthesis; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Thymoma; Transcription, Genetic; Transfection | 1991 |
Combination of mutant EL-4 thymoma cells and EBV-infection in B lymphocyte activation a) EBV-infection of EL-4-activated lymphocytes. b) Use of EL-4 cells as feeders for lymphoblastoid cell lines.
Topics: B-Lymphocytes; Cell Communication; Cell Division; Cell Line; Herpesviridae Infections; Herpesvirus 4, Human; Humans; Kinetics; Lymphocyte Activation; Mutation; Stem Cells; Tetradecanoylphorbol Acetate; Thymoma; Tumor Cells, Cultured | 1990 |
Activation of messenger-independent protein kinases in wild-type and phorbol ester-resistant EL4 thymoma cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Amino Acid Sequence; Animals; Dose-Response Relationship, Drug; Enzyme Activation; Ethers, Cyclic; Glycogen Synthase Kinase 3; Isoquinolines; Mice; Molecular Sequence Data; Okadaic Acid; Oligopeptides; Phosphoproteins; Piperazines; Protein Kinase C; Protein Kinases; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Thymoma; Tumor Cells, Cultured | 1991 |
A rapid colorimetric microassay to detect agonists/antagonists of protein kinase C based on adherence of EL-4.IL-2 cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Carcinogens; Cell Adhesion; Colorimetry; Diterpenes; Dose-Response Relationship, Drug; Enzyme Activation; Indoles; Isoquinolines; Lactams; Phorbol 12,13-Dibutyrate; Phorbol Esters; Piperazines; Protein Kinase C; Reproducibility of Results; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Thymoma; Tumor Cells, Cultured | 1991 |
Transforming growth factor type beta 1 (TGF-beta 1) down-regulates interleukin-2 production and up-regulates interleukin-2 receptor expression in a thymoma cell line.
Topics: Animals; Down-Regulation; Gene Expression; Interleukin-1; Interleukin-2; Mice; Receptors, Interleukin-2; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymoma; Thymus Neoplasms; Transforming Growth Factor beta; Up-Regulation | 1991 |
TPA induction of EL4 resistance to macrophage-released TNF: role of ADP-ribosylation in tumoricidal activities of TNF and other factors.
Topics: Animals; Antibodies; Benzamides; Calcimycin; Cytotoxicity, Immunologic; Cytotoxins; Down-Regulation; Genetic Variation; Macrophage Activation; Mice; Niacinamide; Pertussis Toxin; Poly(ADP-ribose) Polymerase Inhibitors; Recombinant Proteins; Tetradecanoylphorbol Acetate; Thymoma; Thymus Neoplasms; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Virulence Factors, Bordetella | 1990 |
Effect of transforming growth factor beta on the EL4 thymoma variant EL4/6.1: dissociation of inhibition of proliferation from expression of IL-1 and IL-2 receptors.
Topics: Animals; Cell Division; Gene Expression Regulation, Neoplastic; Interleukin-1; Ionomycin; Mice; Receptors, Immunologic; Receptors, Interleukin-1; Receptors, Interleukin-2; Recombinant Proteins; Tetradecanoylphorbol Acetate; Thymoma; Thymus Neoplasms; Transforming Growth Factor beta; Tumor Cells, Cultured | 1990 |
Synthetic peptide corresponding to a conserved domain of the retroviral protein p15E blocks IL-1-mediated signal transduction.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Binding, Competitive; Cell Line; Cytosol; Immunosuppressive Agents; Interleukin-1; Interleukin-2; Isoquinolines; Mice; Peptide Fragments; Piperazines; Protein Kinase C; Receptors, Immunologic; Receptors, Interleukin-1; Retroviridae Proteins; Serum Albumin, Bovine; Signal Transduction; Tetradecanoylphorbol Acetate; Thymoma | 1989 |
The stimulation of EL-4 cells to produce interleukin-2 and its potential use in immunocytotoxicity testing.
Topics: Animals; Cell Division; Concanavalin A; Cytotoxicity Tests, Immunologic; Interleukin-2; Mice; Spleen; T-Lymphocytes, Cytotoxic; Tetradecanoylphorbol Acetate; Thymidine; Thymoma; Thymus Neoplasms; Tritium; Tumor Cells, Cultured | 1989 |
Comparison of phorbol-12-myristate-13-acetate and dioctanoyl-sn-glycerol in the activation of EL4/6.1 thymoma cells.
Topics: Animals; Diglycerides; Ethers; Flow Cytometry; Glycerides; Interleukin-1; Ionomycin; Lymphocyte Activation; Mice; Protein Kinase C; Receptors, Interleukin-2; RNA, Messenger; Tetradecanoylphorbol Acetate; Thymoma; Tumor Cells, Cultured | 1989 |
Phorbol ester induces interleukin-2 receptor on the cell surface of precursor thymocyte leukemia with no rearrangement of T cell receptor beta and gamma genes.
Topics: Antibodies, Monoclonal; Cell Division; Cell Membrane; Cells, Cultured; Child; DNA Restriction Enzymes; Genes; Humans; Interleukin-2; Kinetics; Male; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Receptors, Antigen, T-Cell; Receptors, Immunologic; Receptors, Interleukin-2; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymoma; Thymus Neoplasms | 1987 |
Trans-acting regulatory factors for T cell antigen receptor alpha- and gamma-chain gene expression.
Topics: Animals; Gene Expression Regulation; Gene Products, tat; Mice; Mice, Inbred AKR; Mice, Inbred BALB C; Phenotype; Receptors, Antigen, T-Cell; Receptors, Antigen, T-Cell, alpha-beta; Receptors, Antigen, T-Cell, gamma-delta; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymoma; Transcription Factors; Tumor Cells, Cultured | 1988 |
The effect of phorbol esters on tumor cell sensitivity to macrophage-mediated cytostasis.
Topics: Animals; Carcinogens; Cell Cycle; Cell Division; Macrophages; Mice; Mice, Inbred C57BL; Phorbol Esters; Tetradecanoylphorbol Acetate; Thymoma; Tumor Cells, Cultured | 1989 |
Lipoxygenase inhibitors suppress IL-2 synthesis: relationship with rise of [Ca++]i and the events dependent on protein kinase C activation.
Topics: Animals; Butylated Hydroxyanisole; Calcimycin; Calcium; Cell Line; Enzyme Activation; Humans; Interleukin-2; Kinetics; Lipoxygenase Inhibitors; Masoprocol; Mice; Phenols; Protein Kinase C; Tetradecanoylphorbol Acetate; Thymoma; Thymus Neoplasms | 1987 |
The AKR thymoma BW5147 is able to produce lymphokines when stimulated with calcium ionophore and phorbol ester.
Topics: Animals; Calcimycin; Cell Fusion; Cell Line; Colony-Stimulating Factors; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Substances; Hybridomas; Interferon-gamma; Interleukin-2; Interleukin-3; Lymphokines; Mice; Mice, Inbred AKR; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymoma; Tumor Cells, Cultured | 1988 |
Proteolytic degradation of protein kinase C in the phorbol ester-induced interleukin-2 secreting thymoma cells.
Topics: Animals; Cell Line; Cytosol; Hydrolysis; Immunoblotting; Interleukin-2; Mice; Peptide Fragments; Peptide Mapping; Phosphorylation; Precipitin Tests; Protease Inhibitors; Protein Kinase C; Tetradecanoylphorbol Acetate; Thymoma | 1988 |
The generation of oxygen radicals: a positive signal for lymphocyte activation.
Topics: Animals; Cell Line; Free Radicals; Glutathione; Lymphocyte Activation; Mercaptoethanol; Mice; Oxygen; Pyrrolidonecarboxylic Acid; Tetradecanoylphorbol Acetate; Thiazoles; Thiazolidines; Thymoma; Tumor Cells, Cultured | 1988 |
Construction of human-mouse T cell hybrids that express human T cell-associated surface antigens and allow the chromosomal localization of these antigens.
Topics: Adult; Animals; Antigens, Surface; Cell Fusion; Cell Line; Child, Preschool; Chromosome Banding; Chromosomes, Human; Humans; Hybridomas; Leukemia, Lymphoid; Lymphocyte Activation; Male; Mice; Species Specificity; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymoma; Thymus Neoplasms | 1986 |
Differential regulation of colony-stimulating factors and interleukin 2 production by cyclosporin A.
Topics: Animals; Colony-Stimulating Factors; Cyclosporins; Female; Interleukin-2; Kinetics; Mice; Mice, Inbred CBA; Spleen; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymoma; Thymus Neoplasms | 1987 |
Induction of tumor cell resistance to macrophage-mediated lysis by phorbol esters: a postbinding event.
Topics: Animals; Caenorhabditis elegans Proteins; Carrier Proteins; Cell Line; Cytotoxicity, Immunologic; Lymphoma; Macrophage Activation; Macrophages; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Phorbol Esters; Protein Kinase C; Rats; Rats, Inbred WF; Receptors, Drug; Receptors, Immunologic; Tetradecanoylphorbol Acetate; Thymoma; Thymus Neoplasms | 1986 |