tetradecanoylphorbol acetate has been researched along with Carcinoma, Epidermoid in 280 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 73 (26.07) | 18.7374 |
1990's | 90 (32.14) | 18.2507 |
2000's | 66 (23.57) | 29.6817 |
2010's | 47 (16.79) | 24.3611 |
2020's | 4 (1.43) | 2.80 |
Authors | Studies |
---|---|
Ghadi, DS; Joshi, P; Waghmare, SK | 1 |
Akira, S; Morisaka, H; Sano, S; Takaishi, M | 1 |
Al Matouq, J; Bloom, C; Hansen, LA; Holmes, M; Holmes, TR; Lovas, S; Madson, JG; Nicola, L; Palermo, NY; Rudd, JC; Sioda, N | 1 |
Bajpai, D; Brooks, SR; Cataisson, C; Hasneen, K; Inoue, Y; Kellett, M; Mehdizadeh, S; Morasso, MI; Motegi, SI; Overmiller, A; Palazzo, E; Sawaya, A; Uchiyama, A; Yuspa, SH | 1 |
Du, Z; Fang, Z; Lan, B; Li, E; Liao, L; Meng, L; Shen, J; Wang, M; Wu, B; Wu, J; Xie, W; Xu, L; Xu, X; Zhu, T | 1 |
Bai, F; Hofbauer, GFL; Mi, J; Michel-Dziunycz, PJ; Qin, J; Tommasi di Vignano, A; Wu, X; Zhou, Q; Zu, T | 1 |
Balmain, A; Del Rosario, R; Harris, S; Kandyba, E; Reeves, MQ | 1 |
Balaiya, V; Johnson, LK; Koster, MI; Lakshmanachetty, S | 1 |
Belai, EB; Campanelli, AP; Cavassani, KA; de Oliveira, CE; Garlet, GP; Gasparoto, TH; Ramos, RN; Silva, JS; Torres, SA | 1 |
Chen, H; Ding, F; He, H; Jin, Q; Li, Y; Liu, Z; Luo, A; Ma, J; Sunkel, B; Wang, Q; Xu, C; Zhang, S | 1 |
Angel, JM; Beltran, L; Blando, J; Checkley, LA; Cho, J; DiGiovanni, J; Hursting, SD; Rho, O | 1 |
Antsiferova, M; Feyerabend, TB; Förster, A; Hartmann, K; Hohl, D; Huber, M; Martin, C; Rodewald, HR; Werner, S | 1 |
He, YY; Ming, M; Qiang, L; Zhao, B | 1 |
Guo, S; He, X; Lan, H; Lan, T; Li, J; Li, W; Qi, C; Wang, L; Wei, P; Yang, Y; Ye, J; Zhang, Q | 1 |
Cipolat, S; Hoste, E; Natsuga, K; Quist, SR; Watt, FM | 1 |
García-Fernández, RA; García-Iglesias, MJ; Pérez-Martínez, C | 1 |
Aggarwal, V; Monga, J; Nongalleima, K; Sharma, M; Suthar, SK | 1 |
Chen, CT; Chen, MK; Chou, MY; Chuang, YT; Hsieh, YH; Lin, CW; Lin, FY; Tang, CH; Yang, SF | 1 |
Naseem, I; Salman, M | 1 |
Amberg, N; Glitzner, E; Holcmann, M; Novoszel, P; Sibilia, M; Stulnig, G | 1 |
Fuchs, E; Oristian, D; Oshimori, N | 1 |
Adams, RA; Boyle, GM; D'Souza, MM; Korica, N; Panizza, B; Parsons, PG; Pierce, CJ; Wallwork, B | 1 |
Brady, M; Brennan-Crispi, DM; Hossain, C; Mahoney, MG; Riobo, NA; Sahu, J | 1 |
Li, EM; Liao, LD; Long, L; Xie, JJ; Xie, YM; Xu, LY; Zhang, XD | 1 |
Bauer, SJ; Havighurst, TC; Kim, K; Singh, A; Verma, AK; Wheeler, DL | 1 |
de Gruijl, F; Rebel, H; Tensen, K; van de Glind, G; van Kempen, M | 1 |
Cataisson, C; Dubois, W; Dwyer, J; Hoover, S; Klosterman, M; Liu, F; Merlino, G; Michalowski, AM; Rodrigues, KB; Ryscavage, A; Shibuya, K; Simpson, MR; Wright, L; Yuspa, SH; Zhuang, A | 1 |
Alitalo, K; Harjunen, V; Heljasvaara, R; Holopainen, T; Honkanen, HK; Izzi, V; Petäistö, T; Pihlajaniemi, T | 1 |
Cannon, RE; Diwan, BA; Germolec, DR; Liu, J; Tennant, RW; Tokar, EJ; Trempus, CS; Waalkes, MP; Ward, JM | 1 |
Hori, Y; Iigo, M; Imai, T; Kitahashi, T; Sugimura, T; Takahashi, M; Takasuka, N; Wakabayashi, K; Yoshimi, N | 1 |
Ashton, GH; Baldeschi, C; Brunton, VG; Canel, M; Doyle, B; Frame, MC; Green, TP; Mackintosh, LJ; Mason, SM; Sansom, OJ; Serrels, A; Serrels, B | 1 |
Arbeit, JM; Kladney, RD; Martin, RJ; Neumann, RG; Scortegagna, M | 1 |
Dziadziuszko, H; Glosnicka, R; Graczyk, A; Jankowski, D; Jaskiewicz, K; Juzeniene, A; Kaliszewski, M; Kunikowska, D; Kwasny, M; Kwitniewski, M; Ma, LW; Moan, J; Peksa, R | 1 |
Kalinovsky, T; Niedzwiecki, A; Rath, M; Roomi, MW; Roomi, NW | 1 |
Adegboyega, P; Batra, V; Cheepala, SB; Clifford, JL; Digiovanni, J; Gill, JN; Kleiner, HE; Nathan, C; Stein, J; Syed, Z | 1 |
Desciak, EB; Eliezri, YD; Owens, DM; Ratner, D; Stumpfova, M | 1 |
Cowan, BJ; Cowan, KN; Laird, DW; Langlois, S; Shao, Q | 1 |
Ambudkar, SV; Garfield, SH; Lee, A; Li, L; Maloney, DJ; Shukla, S; Yuspa, SH | 1 |
Bode, AM; Byun, S; Dong, Z; Hwang, MK; Lee, HJ; Lee, KW; Song, NR | 1 |
Jin, JY; Leshin, B; Lutfeali, S; Miliani de Marval, P; Selim, MA; Zhang, JY | 1 |
Dev Sharma, P; Manon, B; Sharma, M; Vir Singh, T; Vyas, S | 1 |
Kesselring, R; Pries, R; Thiel, A; Wollenberg, B | 1 |
Brotman, JJ; Judd, NP; Lewis, JS; Pittman, ME; Schreiber, RD; Uppaluri, R; Winkler, AE | 1 |
Aengeneyndt, B; Flechtenmacher, C; Gheit, T; Gissmann, L; Gröne, HJ; Kloz, U; Kopp-Schneider, A; Mueller-Decker, K; Tommasino, M; Viarisio, D | 1 |
Dominik, P; Dulak, J; Grochot-Przeczek, A; Jozkowicz, A; Kotlinowski, J; Kozakowska, M; Lackowska, B; Mazan, A; Muchova, L; Nowak, W; Pratnicki, A; Ratajska, A; Sierpniowska, A; Skrzypek, K; Sokolowska, M; Taha, H; Vitek, L; Was, H | 1 |
Arbeit, JM; Chung, CH; Day, R; Dong, Y; Grabowska, D; Humphrey, P; Kladney, RD; Lewis, J; Li, A; Michel, LS; Wang, J; Weber, JD; Zhang, K | 1 |
Chauhan, CS; Monga, J; Sharma, M | 1 |
Chaiswing, L; Dhar, SK; Oberley, TD; St Clair, DK; Tangpong, J | 1 |
Aoi, J; Araki, K; Endo, M; Hirakawa, S; Horiguchi, H; Ihn, H; Ito, T; Jinnin, M; Kadomatsu, T; Miyata, K; Nakano, M; Odagiri, H; Ogata, A; Oike, Y; Yano, M | 1 |
Chung, WY; Hwang, YS; Park, KK | 1 |
Maalouf, SW; Owens, DM; Theivakumar, S | 1 |
Ai, W; Huang, S; Li, J; Liu, C; Wang, TC; Yu, F; Yu, T; Zheng, H | 1 |
Andradas, C; Flores, JM; Guzmán, M; Paramio, JM; Pérez-Gómez, E; Quintanilla, M; Sánchez, C | 1 |
Ansari, KM; Das, M; Kumar, R | 1 |
Alameda, JP; Bravo, A; Casanova, ML; Dupuy, AJ; Navarro, M; Page, A; Quintana, RM; Ramírez, A; Sánchez-Viera, M | 1 |
Hayward, R; Lo, RS; Marais, R; Martin, M; Niculescu-Duvaz, D; Sanchez-Laorden, B; Springer, C; Viros, A; Yashar, S; Yu, CC; Zambon, A | 1 |
Braeuning, A; Münzel, PA; Schwarz, M | 1 |
Itoi, S; Katayama, I; Murota, H; Terao, M | 1 |
Ariztia, EV; Munshi, HG; Stack, MS; Wu, YI | 1 |
Berger, I; Furstenberger, G; Marks, F; Muller-Decker, K; Neufang, G; Neumann, M | 1 |
Grenman, R; Hieta, N; Impola, U; Jahkola, T; Jeskanen, L; Kähäri, VM; Saarialho-Kere, U; Suomela, S; Toriseva, M | 1 |
Gajda, G; Lecuyer, D; McLean, JR; McNamee, JP; Thansandote, A; Tryphonas, L | 1 |
Donnenberg, AD; Gooding, W; Kuss, I; Whiteside, TL | 1 |
Kannan, S; Kirtane, BM; Mansukhani, NP; Mulherkar, R; Naresh, KN; Ramchandani, A | 1 |
Adiseshaiah, P; Reddy, SP; Vuong, H | 1 |
Bartoli, C; Cataltepe, S; Dragani, TA; Fabbri, A; Falvella, FS; Gariboldi, M; Hayashizaki, Y; Mancuso, MT; Maurichi, A; Okazaki, Y; Pazzaglia, S; Peissel, B; Pilotti, S; Saran, A; Silverman, GA; Spinola, M; Tanuma, J; Zaffaroni, D | 1 |
Abdul-Jabbar, I; Barnes, LM; Dahler, AL; Popa, C; Saunders, NA; Serewko-Auret, MM; Smith, L; Wong, CF | 1 |
Kupper, TS; Morales, RE; Murphy, JE; Scott, J | 1 |
Ness, KJ; Oberley, TD; Verma, AK; Wheeler, DL | 2 |
Kimura, S; Murata, Y; Sasaguri, Y; Tanimoto, A; Wang, KY; Xu, H | 1 |
Beltrán, L; Bol, DK; Carbajal, S; DiGiovanni, J; Jiang, J; Kiguchi, K; Matsumoto, T; Rosenberg, MP; Ruffino, L | 1 |
Heo, DS; Kim, KH; Lee, DW; Lee, SG; Park, BJ; Park, SW; Song, SH; Sung, MW | 1 |
Albor, A; Babcock, M; Bowden, GT; El-Hizawi, S; Hennings, H; Horn, EJ; Kulesz-Martin, M; Liu, Y; Lozano, G; Vanderbeek, GE; Weinberg, WC | 1 |
Athar, M; Bhasin, G; Kauser, H | 1 |
Ho, CT; Hong, J; Hou, Z; Huang, MT; Lambert, JD; Rosen, RT; Ryu, JH; Sang, S; Stark, RE; Tian, S; Yang, CS | 1 |
Al-Hassani, M; Darst, M; Lewis, DA; Li, T; Travers, JB; Travers, JM; Yi, Q | 1 |
Chimeno Zoth, SA; Collet, AM; Heber, E; Itoiz, ME; Schwint, AE | 1 |
Iizuka, H; Itoh, Y; Nakajima, S; Sakata, I; Takahashi, H | 1 |
Hanai, T; Inoue, H; Mine, S; Mori, M; Nishida, K; Okamoto, M; Udagawa, H; Utsunomiya, T | 1 |
Kitamura, T; Maruyama, T; Narumiya, S; Niho, N; Sato, H; Shoji, Y; Sugimoto, Y; Sugimura, T; Takahashi, M; Takasuka, N; Wakabayashi, K | 1 |
Aoki, I; Colledge, WH; Foidart, JM; Hata, R; Kato, Y; Koshika, S; Kubota, Y; Nagashima, Y; Sakai, N; Thompson, EW; Tsukuda, M; Yao, M | 1 |
Cichy, J; Kulig, P; Puré, E | 1 |
Abdel-Fattah, R; Glick, A; Hennings, H; Maiberger, P; Rehman, I | 1 |
Alters, W; Chaiswing, L; Li, Y; Oberley, TD; Verma, AK; Wheeler, DL | 1 |
Das, M; Dogra, RK; Khanna, SK; Rastogi, S | 1 |
Liu, W; Xiao, X; Zeng, Z | 1 |
Chen, Z; Hicks, J; Honeycutt, KA; Koster, MI; Miers, M; Nuchtern, J; Roop, DR; Shohet, JM | 1 |
Angel, P; Breitenbach, U; Fürstenberger, G; Gebhardt, C; Hartenstein, B; Hess, J; Mauch, C; Rhiemeier, V; Richter, KH; Vogt, I | 1 |
Fischer, SM; He, G; Hwang, DH; Sung, YM | 1 |
Aziz, MH; Manoharan, H; Verma, AK; Wheeler, DL | 1 |
Chen, WT; Li, J; Pan, HY; Zhang, P; Zhang, ZY; Zhou, XJ | 1 |
Bae, DS; Darwiche, N; Glick, AB; Hennings, H; Perez-Lorenzo, R; Ryscavage, A; Wright, L; Yuspa, SH | 1 |
Dahler, AL; Guminski, A; Rickwood, D; Saunders, NA; Teakle, N | 1 |
Bower, KA; Chen, G; Ding, M; Gao, TW; Gao, Y; Ke, Z; Luo, J; Ma, C; Odetallah, M; Wang, J | 1 |
Kim, Y; Klein-Szanto, A; Macias, E; Miliani de Marval, PL; Rodriguez-Puebla, ML | 1 |
Kemkers, A; Pries, R; Riebe, C; Wollenberg, B | 1 |
Furuya, M; Kelly-Spratt, KS; Kemp, CJ; Parghi, SS; Ruddell, A | 1 |
Ananthaswamy, HN; Li, Y; Oberley, TD; Verma, AK; Wheeler, DL | 1 |
Cassel, D; Glaser, L; Whiteley, B; Zhuang, YX | 1 |
Yuspa, SH | 1 |
Klein-Szanto, AJ; Nelson, KG; Shah, Y; Slaga, TJ | 1 |
Emmerson, A; Grabham, P; Parkinson, EK | 1 |
Emmerson, A; Parkinson, EK | 1 |
Emmerson, A; Gorman, PA; Parkinson, EK; Pera, MF | 1 |
Panneerselvam, M; Sahai, A; Salomon, DS; Smith, KB | 1 |
Burns, JC; Murray, BK | 1 |
Fehnel, P; Losonczy, I; Pannerselvam, M; Sahai, A; Salomon, DS; Smith, KB | 1 |
Fox, CF; Iwashita, S | 1 |
King, AC; Moon, SO; Palfrey, HC | 1 |
Evans, RM; Potter, E; Rosenfeld, MG; Supowit, SC | 1 |
Czech, MP; Davis, RJ | 2 |
Bernfeld, P; Homburger, F | 1 |
Anderson, WB; Cooper, HL; Feuerstein, N; Sahai, A; Salomon, DS | 1 |
Stenbäck, F | 2 |
Froscio, M; Guy, GR; Jones, MJ; Murray, AW; Pappalardo, S; Tapley, PM | 1 |
Hirao, Y; Hopp, L; Izumi, K; Oyasu, R | 1 |
Aubert, ML; Bonjour, JP; Rizzoli, R; Sappino, AP | 1 |
Asaoka, Y; Chang, WC; Liu, YW; Suzuki, H; Yamamoto, S; Yoshimoto, T | 2 |
Bergh, J; Heldin, P; Teder, P | 1 |
Chida, K; Ikuta, T; Kuroki, T; Murakami, A; Tagawa, T | 1 |
Blessing, M; Hogan, BL; King, LE; Nanney, LB | 1 |
Owens, DM; Smart, RC; Spalding, JW; Tennant, RW | 1 |
Kaneko, F; Maruyama, K; Ono, I; Zhang, JZ | 1 |
Boyd, D; Clayman, G; Juarez, J; Nakajima, M; Nicolson, GL; Saya, H; Tanabe, KK | 1 |
Buchdunger, E; Lydon, NB; Mett, H; Meyer, T; Müller, M; Regenass, U; Zimmermann, J | 1 |
Conti, CJ; Robles, AI | 1 |
Dobrowolska, G; Krebs, EG; Litchfield, DW | 1 |
Eppley, RM; Hines, FA; Lambert, LA | 1 |
Boukamp, P; Fitzgerald, DJ; Fusenig, NE; Mesnil, M; Piccoli, C; Yamasaki, H | 1 |
French, JE; Hansen, L; Libbus, BL; Mahler, J; Spalding, J; Tennant, RW; Tice, RR | 1 |
Atsumi, T; Hosoi, K; Ueha, T | 1 |
Bowden, GT; Domann, FE; Finch, JS; Levy, JP | 1 |
Osaki, T; Ueta, E; Umazume, M; Yamamoto, T | 1 |
Gembardt, C; Kühborth, B; Mellert, W; Munk, R | 1 |
Hori, Y; Kinoshita, N; Moon, DC; Nakayama, J; Terao, H; Urabe, A | 1 |
Bucana, CD; Fidler, IJ; Xie, B | 1 |
Iwatsuki, K; Kaneko, F; Maruyama, K; Ono, I; Zhang, JZ | 1 |
Agarwal, R; Katiyar, SK; Mukhtar, H | 1 |
Glick, AB; Hennings, H; Krsmanovic, LS; Lowry, DT; Sly, LM; Yuspa, SH | 1 |
Geng, Y; Gross, V; Lotz, M; Villiger, PM; Zhang, B | 1 |
DeLeo, VA; Harth, Y; Matsui, MS; Wang, N; Warmuth, I | 1 |
Jensen, TC; Johnson, TM; Majmudar, G; Nelson, BR; Voorhees, JJ | 1 |
Garrett, LR; McDougall, JK; Perez-Reyes, N; Smith, PP | 1 |
Ansel, J; Krutmann, J; Luger, TA; Schauer, E; Schwarz, A; Schwarz, T; Trautinger, F | 1 |
Aldaz, CM; Conti, CJ; DiGiovanni, J; Slaga, TJ; Walker, SE | 1 |
Dlugosz, AA; Hennings, H; Strickland, JE; Yuspa, SH | 1 |
Bianchi, AB; Conti, CJ; Fischer, SM; Rinchik, EM; Robles, AI | 1 |
DiBenedetto, PJ; Gilani, A; Gilchrest, BA; Harkness, DD; Yaar, M | 1 |
Chung, KN; Jung, MO; Kondratyev, AD | 1 |
Jetten, AM; Owens, DM; Smart, RC; Zainal, TA | 1 |
Baselga, J; Kim, YM; Mendelsohn, J; Pandiella, A | 1 |
Aldaz, CM; Battalora, MS; Conti, CJ; DiGiovanni, J; Johnston, DA; Slaga, TJ | 1 |
Kaszkin, M; Kinzel, V; Richards, J | 1 |
Imamura, T; Kobayashi, M; Morioka, H; Sawa, T; Takada, Y; Takata, Y; Yang, GH | 1 |
Fujisawa, Y; Hirako, Y; Kitajima, Y; Owada, MK; Owaribe, K; Seishima, M; Yaoita, H | 1 |
Cano, A; Conti, CJ; Duran, H; Jorcano, JL; Larcher, F; Murillas, R; Quintanilla, M; Robles, AI | 1 |
Dannenberg, AJ; Inoue, H; Mestre, JR; Sacks, PG; Schantz, SP; Subbaramaiah, K; Tanabe, T | 1 |
Reiners, JJ; Singh, KP | 1 |
Goodrow, T; Klein-Szanto, AJ; Liu, SC; Morris, R; Zhang, SY | 1 |
Muller, HK; Qu, M; Woods, GM | 1 |
Conti, CJ; Reiners, JJ; Singh, KP; Yoon, HL | 1 |
Foley, JF; Kim, TW; Maronpot, RR; Porter, KL; Smart, RC | 1 |
Miyazaki, H; Murakami, K; Ozawa, Y; Suzuki, Y | 1 |
Chang, WC; Chen, BK; Liaw, YW; Liu, YW | 1 |
Kuan, CY; Lee, SC; Wen, ZD; Yang, SD | 1 |
Denning, MF; Ellerbroek, SM; Green, KJ; Guy, SG; Kowalczyk, AP; Norvell, SM | 1 |
Boyd, D; Goepfert, H; Simon, C | 1 |
Dahler, AL; Dicker, AJ; Jones, SJ; Saunders, NA | 1 |
Devoe, G; Gear, R; Heffelfinger, SC; Miller, MA | 1 |
Cerneus, DP; den Brok, JH; Hall, DW; Leuven, PJ; van den Hoven, WE; Wauben-Penris, PJ | 1 |
Deng, C; Fernandez-Salas, E; Hennings, H; Mirosh, E; Morgan, DL; Shalizi, A; Stanulis, E; Weinberg, WC; Yuspa, SH | 1 |
Fischer, SM; La, E; Locniskar, MF; Muga, SJ | 1 |
Carothers, AM; Dannenberg, AJ; Grunberger, D; Koboldt, C; Masferrer, JL; Mestre, JR; Michaluart, P; Sacks, PG; Subbaramaiah, K; Tanabe, T; Zweifel, BS | 1 |
Owens, DM; Smart, RC; Wei, S | 1 |
Kawahara, E; Nakanishi, I; Tokuda, R | 1 |
Braun, DP; Faber, LP; Ortegel, JW; Staren, ED; Warren, WH | 1 |
Coghlan, LG; Conti, CJ; DiGiovanni, J; Fischer, SM; Gimenez-Conti, I; Kleiner, HE; Rundhaug, JE; Slaga, TJ | 1 |
Dannenberg, AJ; Michaluart, P; Sporn, MB; Subbaramaiah, K | 1 |
Benavides, F; Conti, CJ; Klingelberger, EA; Stern, MC | 1 |
Brinkley, BR; Go, C; He, W; Huang, J; Li, P; Wang, XJ; Zhong, L | 1 |
Gaiotti, D; Hansen, L; Michael, E; Nees, M; Woodworth, CD | 1 |
Beltrán, L; Bol, D; Carbajal, S; Chan, K; DiGiovanni, J; Jorcano, J; Kiguchi, K; Moats, S | 1 |
Dreckschmidt, NE; Jansen, AP; Oberley, TD; Verma, AK; Verwiebe, EG; Wheeler, DL | 1 |
Biozzi, G; Covelli, V; Mancuso, M; Pazzaglia, S; Primerano, B; Rebessi, S; Saran, A | 1 |
Klein-Szanto, A; Zhang, S | 1 |
Beissert, S; Kupper, TS; Mayer, C; Rossiter, H; Schön, MP; Tschachler, E; Wienrich, BG | 1 |
Bode, AM; Chen, N; Dong, Z; Flavell, RA; Ma, WY; Nomura, M; She, QB; Wang, L | 1 |
Owens, DM; Watt, FM | 1 |
Alexander-Lister, LD; Aznavoorian, S; Engler, JA; Hallit, SL; Moore, BA; Windsor, LJ | 1 |
Boonstra, J; de Groot, RP; de Laat, SW; Kruijer, W; Rijken, PJ; Verkleij, AJ | 1 |
Fujiwara, O; Imaida, K; Kato, K; Kuzutani, K; Ogiso, T; Shirai, T; Wang, J | 1 |
Bartlett, JD; Grenman, R; Iwata, K; Palosaari, H; Parikka, M; Salo, T; Sorsa, T; Srinivas, R; Stenman, UH; Väänänen, A | 1 |
Chow, KC; Wang, LS; Wu, YC | 1 |
Grénman, R; Moilanen, M; Pirilä, E; Salo, T; Sorsa, T | 1 |
Angel, P; Breitenbach, U; Dittrich, BT; Gebhardt, C; Richter, KH; Tuckermann, JP | 1 |
Iversen, OH; Iversen, UM | 1 |
Melchionne, S; Segal, A; Seidman, I; Smith, AC; Tseng, SS; Van Duuren, BL | 1 |
Fry, RJ; Grube, DD; Ley, RD | 1 |
Segal, A; Van Duuren, BL | 1 |
Goerttler, L; Loehrke, H | 1 |
Chouroulinkov, I; Gentil, A; Grover, PL; Sims, P | 1 |
Bhisey, RA; Sirsat, SM | 1 |
Heidtmann, HH; Moldenhauer, G; Schirrmacher, V; Schwartz-Albiez, R; Wolf, D | 1 |
Baba, T; Fujisawa, H; Horiuchi, S; Naito, Y; Otsuka, F | 1 |
Glick, A; Greenhalgh, D; Hennings, H; Morgan, D; Welty, D; Yuspa, SH | 1 |
Bianchi, AB; Conti, CJ; Fischer, SM; Gimenez-Conti, IB; Reiners, JJ; Slaga, TJ | 1 |
Anderson, L; Langdon, SP; Miller, WR; Rabiasz, GJ; Ritchie, AA; Smyth, JF | 1 |
Ballestín, C; Bauluz, C; Conti, CJ; Díaz-Guerra, M; Jorcano, JL; Larcher, F; Quintanilla, M | 1 |
Jones, GJ; Thornley, AL | 1 |
Jokura, Y; Kitajima, Y; Nishizawa, Y; Owaribe, K; Yaoita, H | 1 |
Bartlett, JM; Crew, AJ; Langdon, SP; Miller, EP; Miller, WR; Rabiasz, GJ; Scott, WN; Smyth, JF | 1 |
Bassols, A; Baulida, J; Onetti, R | 1 |
Clasen, BP; Kaffenberger, W; van Beuningen, D | 1 |
Maruo, T; Matsuo, H; Mochizuki, M; Nishino, R | 1 |
Bonham, K; Bowden, GT; Krieg, P; Ostrowski, LE | 1 |
Aldaz, CM; Chiba, M; Conti, CJ; Klein-Szanto, AJ | 1 |
Iwashita, S; Mitsui, K; Senshu-Miyaike, M; Shoji-Kasai, Y | 1 |
Nischt, R; Rentrop, M; Schweizer, J; Winter, H | 1 |
Andrews, K; Bowden, GT; Finch, J; Fürstenberger, G; Krieg, P; Ootsuyama, A; Slaga, T; Tanooka, H | 1 |
Cantu, AR; Reiners, JJ; Rupp, T; Thai, G | 1 |
Cappel, RE; Gilbert, HF; Kodari, E; Reiners, JJ | 1 |
Aizu, E; Ishihara, M; Jiang, H; Kamegaya, Y; Kato, R; Nakadate, T; Yamamoto, S | 1 |
Greenhalgh, DG; Hennings, H; Robinson, VA; Welty, DJ; Yuspa, SH | 1 |
Gonzalez, FA; Heppel, LA; Huang, NN; Wang, DJ | 1 |
Singh, N | 2 |
Davis, RJ; Northwood, IC | 2 |
Hirai, M; Kobayashi, M; Shimizu, N | 1 |
Garcin, D; Jacquemont, B; Madjar, JJ; Massé, T | 2 |
Caselitz, J; Hamper, K; Lunau, U; Schmiegelow, P; Walther, B | 1 |
Inoue, S; Kitajima, Y; Nagao, S; Nagata, K; Nozawa, Y; Yaoita, H | 2 |
Chakravarty, R; Rice, RH; Rong, XH | 1 |
Conti, CJ; DiGiovanni, J; Ewing, MW; Phillips, JL; Slaga, TJ | 1 |
Gill, TJ; Shinozuka, H; Yokota, K | 1 |
Dlugosz, AA; Dzubow, L; Gilmour, SK; Hietala, O; O'Brien, TG; O'Donnell, K | 1 |
Gupta, KP; Mehrotra, NK | 1 |
Kitajima, Y; Sheu, HM; Yaoita, H | 1 |
Kim, YS; Park, KK | 1 |
Haigler, HT; Kraft, AS; William, F | 1 |
Boonstra, J; Ponec, M | 1 |
Bonham, K; Bowden, GT; Cress, AE; Embry, T; Gibson, D; Jaffe, DR; Roberts, RA | 1 |
Bowden, GT; Jaffe, DR | 2 |
Alfonzo, RG; Gonzalez, FA; Heppel, LA; Toro, JR | 1 |
Gill, TJ; Hattori, A; Kunz, HW; Shinozuka, H; Yokota, K | 1 |
Barritault, D; Chua, CC; Geiman, DE; Ladda, RL | 1 |
Greenhalgh, DA; Harper, JR; Lacal, JC; Reynolds, SH; Strickland, JE; Yuspa, SH | 1 |
Beguinot, L; Hanover, JA; Ito, S; Pastan, I; Richert, ND; Willingham, MC | 1 |
Chiba, M; Klein-Szanto, AJ; Maley, MA | 1 |
Rice, RH; Rubin, AL | 1 |
Bell, RM; Czech, MP; Davis, RJ; Ganong, BR | 1 |
Fearn, JC; King, AC | 1 |
Shimizu, N | 1 |
Macara, IG | 1 |
Cooper, HL; Feuerstein, N; Sahai, A; Salomon, DS | 1 |
Koeffler, HP; Munker, M; Munker, R; Saxton, RE | 1 |
Prywes, R; Roeder, RG | 1 |
Aldaz, CM; Conti, CJ; Klein-Szanto, AJ; Slaga, TJ | 1 |
Conti, CJ; DiGiovanni, J; Ewing, MW; Kruszewski, FH; Slaga, TJ | 1 |
Bowden, GT; Breathnach, R; Finch, J; Krieg, P; Matrisian, L; O'Connell, JF; Ostrowski, LE; Patskan, G; Phillips, J; Slaga, TJ | 1 |
Bell, RM; Davis, RJ; Faucher, M; Gironès, N; Hannun, YA | 1 |
Miyata, Y; Nishida, E; Sakai, H | 1 |
Aerts, RJ; de Laat, SW; Moolenaar, WH; Tertoolen, LG | 1 |
Castagnola, J; MacLeod, C; Mendelsohn, J; Sunada, H; Taetle, R | 1 |
Meldolesi, J; Pandiella, A; Vicentini, LM | 1 |
Bowden, GT; Breathnach, R; Briand, JP; Fürstenberger, G; Krieg, P; Leroy, P; Matrisian, LM | 1 |
Bowden, GT; Jaffe, D | 1 |
Creasia, D; Kripke, ML; Strickland, PT | 1 |
Panneerselvam, M; Sahai, A; Salomon, DS | 1 |
Hennings, H; Yuspa, SH | 1 |
Blasi, F; Grimaldi, G; Locatelli, EK; Stoppelli, MP; Verde, P | 1 |
Ando, Y; Ichijo, M; Moriyama, I; Nakanishi, A; Noda, T; Saitoh, S; Yoh, S | 1 |
Pittelkow, MR; Scott, RE; Wille, JJ | 1 |
4 review(s) available for tetradecanoylphorbol acetate and Carcinoma, Epidermoid
Article | Year |
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Non-melanoma skin cancer in mouse and man.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Disease Models, Animal; Disease Progression; Genes, p53; Genes, ras; Humans; Melanoma; Mice; Mutation; Neoplasm Invasiveness; Neoplastic Stem Cells; Papilloma; Risk Assessment; Skin; Skin Neoplasms; Species Specificity; Tetradecanoylphorbol Acetate | 2013 |
Protein kinase Cepsilon and development of squamous cell carcinoma, the nonmelanoma human skin cancer.
Topics: Animals; Apoptosis; Carcinoma, Squamous Cell; Humans; Mice; Neoplasms, Radiation-Induced; Oncogenes; Ornithine Decarboxylase; Protein Kinase C-epsilon; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2006 |
Differential gene expression during tumor promotion and progression in the mouse skin model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Actins; Animals; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cocarcinogenesis; DNA; Gene Expression Regulation, Neoplastic; Matrix Metalloproteinase 3; Metalloendopeptidases; Methylnitronitrosoguanidine; Mice; Neoplasm Metastasis; Neoplasm Proteins; Neoplasms, Multiple Primary; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Ubiquitins | 1991 |
The pleomorphic adenoma of salivary glands transplanted on athmymic mice. A lightmicroscopical and immunohistochemical investigation.
Topics: Adenoma, Pleomorphic; Animals; Autoradiography; Carcinoembryonic Antigen; Carcinoma, Squamous Cell; Cell Division; Fibronectins; Histocytochemistry; Humans; Immunochemistry; Immunoglobulin A; Immunoglobulin A, Secretory; Immunoglobulin G; Immunoglobulin M; Keratins; Lactoferrin; Lectins; Mice; Mice, Nude; Muramidase; Neoplasm Transplantation; Salivary Gland Neoplasms; Tetradecanoylphorbol Acetate; Transplantation, Heterologous | 1985 |
276 other study(ies) available for tetradecanoylphorbol acetate and Carcinoma, Epidermoid
Article | Year |
---|---|
Isolation of cancer stem cells from skin squamous cell carcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogenesis; Carcinogens; Carcinoma, Squamous Cell; Disease Models, Animal; Humans; Mice; Neoplastic Stem Cells; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2022 |
Keratinocyte Regnase-1, a Downregulator of Skin Inflammation, Contributes to Protection against Tumor Promotion by Limiting Cyclooxygenase-2 Expression.
Topics: Acetates; Animals; Carcinogenesis; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cyclooxygenase 2; Dermatitis; Humans; Inflammation; Keratinocytes; Lithostathine; Mice; RNA, Messenger; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2023 |
Targeting 14-3-3ε activates apoptotic signaling to prevent cutaneous squamous cell carcinoma.
Topics: 14-3-3 Proteins; 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Apoptosis; Carcinogens; Carcinoma, Squamous Cell; cdc25 Phosphatases; Cell Line, Tumor; Cytoplasm; Female; Humans; Keratinocytes; Male; Mice; Mice, Knockout; Neoplasms, Experimental; Protein Multimerization; Skin Neoplasms; Tetradecanoylphorbol Acetate; Xenograft Model Antitumor Assays | 2021 |
Loss of DLX3 tumor suppressive function promotes progression of SCC through EGFR-ERBB2 pathway.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aged; Animals; Carcinogens; Carcinoma, Squamous Cell; Disease Models, Animal; ErbB Receptors; Female; Homeodomain Proteins; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neoplasm Grading; Receptor, ErbB-2; Signal Transduction; Skin Neoplasms; Survival Rate; Tetradecanoylphorbol Acetate; Transcription Factors | 2021 |
Cell Signaling Pathway in 12-O-Tetradecanoylphorbol-13-acetate-Induced LCN2 Gene Transcription in Esophageal Squamous Cell Carcinoma.
Topics: Carcinoma, Squamous Cell; Cell Line, Tumor; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Gene Expression Regulation, Neoplastic; Humans; Lipocalin-2; MAP Kinase Signaling System; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Neoplasm Proteins; Promoter Regions, Genetic; Protein Kinase C-alpha; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription, Genetic | 2017 |
The ARE-binding protein Tristetraprolin (TTP) is a novel target and mediator of calcineurin tumor suppressing function in the skin.
Topics: Animals; Animals, Newborn; Calcineurin; Calcineurin Inhibitors; Carcinoma, Squamous Cell; Cells, Cultured; Cytokines; Female; Gene Expression; Humans; Inflammation Mediators; Keratinocytes; Mice, Inbred C57BL; Mice, Knockout; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tristetraprolin; Ultraviolet Rays | 2018 |
Multicolour lineage tracing reveals clonal dynamics of squamous carcinoma evolution from initiation to metastasis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cell Lineage; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Clonal Evolution; Epithelial Cells; Female; Gene Expression Regulation, Neoplastic; Genes, ras; Genetic Predisposition to Disease; Male; Mice, Transgenic; Mutation; Neoplasms, Experimental; Phenotype; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Tumor Burden | 2018 |
TRP63/TP63 loss accelerates skin tumorigenesis through activation of Wnt/β-catenin signaling.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cell Differentiation; Cell Line; Cell Proliferation; Cell Transformation, Neoplastic; Gene Expression Regulation, Neoplastic; Genetic Predisposition to Disease; Humans; Mice, Knockout; Mice, Nude; Phosphoproteins; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Trans-Activators; Transcription Factors; Tumor Burden; Tumor Suppressor Proteins; Wnt Signaling Pathway | 2018 |
PD-1 blockage delays murine squamous cell carcinoma development.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antibodies, Monoclonal; Carcinoma, Squamous Cell; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cytokines; Female; Flow Cytometry; Immunoenzyme Techniques; Interferon-gamma; Mice; Mice, Inbred BALB C; Papilloma; Programmed Cell Death 1 Receptor; Tetradecanoylphorbol Acetate | 2014 |
S100A14: novel modulator of terminal differentiation in esophageal cancer.
Topics: Calcium; Calcium-Binding Proteins; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Filaggrin Proteins; G1 Phase Cell Cycle Checkpoints; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Intermediate Filament Proteins; Neoplasm Grading; Neoplasm Staging; Protein Precursors; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription Factors | 2013 |
Metformin inhibits skin tumor promotion in overweight and obese mice.
Topics: Adenylate Kinase; Adiponectin; Animals; Body Weight; Carcinogenesis; Carcinoma, Squamous Cell; Diet; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Insulin; Insulin-Like Growth Factor I; Leptin; Mechanistic Target of Rapamycin Complex 1; Metformin; Mice; Mice, Obese; Multiprotein Complexes; Neoplasms, Experimental; Obesity; Overweight; Papilloma; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Sirolimus; Skin Neoplasms; Tetradecanoylphorbol Acetate; TOR Serine-Threonine Kinases | 2014 |
Mast cells are dispensable for normal and activin-promoted wound healing and skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Activins; Animals; Carcinogens; Carcinoma, Squamous Cell; Chemotaxis; Female; Humans; Injections, Intralesional; Mast Cells; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Neovascularization, Pathologic; Neutrophil Infiltration; Papilloma; Proto-Oncogene Proteins c-kit; Recombinant Proteins; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Wound Healing | 2013 |
Mammalian SIRT2 inhibits keratin 19 expression and is a tumor suppressor in skin.
Topics: Animals; Antigens, CD34; Apoptosis; Carcinogenesis; Carcinoma, Squamous Cell; Cell Proliferation; DNA Repair; Down-Regulation; Gene Expression Regulation, Neoplastic; Humans; Keratin-15; Keratin-19; Keratinocytes; Membrane Proteins; Mice; Mice, Knockout; RNA, Small Interfering; Sirtuin 2; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Burden; Up-Regulation | 2014 |
Slit2 promotes tumor growth and invasion in chemically induced skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Basement Membrane; Blood Vessels; Bromodeoxyuridine; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Collagen Type IV; Humans; Immunohistochemistry; Intercellular Signaling Peptides and Proteins; Matrix Metalloproteinase 2; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Confocal; Neoplasm Invasiveness; Nerve Tissue Proteins; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Burden | 2014 |
Epidermal barrier defects link atopic dermatitis with altered skin cancer susceptibility.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cell Communication; Cell Differentiation; Cell Transformation, Neoplastic; Cytokines; Dermatitis, Atopic; Disease Models, Animal; Epidermis; Keratinocytes; Membrane Proteins; Mice, 129 Strain; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Mice, Nude; NK Cell Lectin-Like Receptor Subfamily K; Papilloma; Permeability; Plakins; Protein Precursors; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Thymic Stromal Lymphopoietin; Time Factors | 2014 |
In vivo long-term effects of retinoic acid exposure in utero on induced tumours in adult mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Carcinogens; Carcinoma, Squamous Cell; Drug Administration Schedule; Female; Keratoacanthoma; Male; Mice; Papilloma; Pregnancy; Skin Neoplasms; Tetradecanoylphorbol Acetate; Treatment Outcome; Tretinoin | 2014 |
Topical (+)-catechin emulsified gel prevents DMBA/TPA-induced squamous cell carcinoma of the skin by modulating antioxidants and inflammatory biomarkers in BALB/c mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acacia; Administration, Topical; Animals; Antioxidants; Biomarkers; Carcinoma, Squamous Cell; Catechin; Dinoprostone; Drug Evaluation, Preclinical; Emulsions; Humans; Inflammation Mediators; Interleukin-1beta; Interleukin-6; Male; Mice; Mice, Inbred BALB C; Nitric Oxide Synthase Type II; Plant Extracts; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2014 |
Resveratrol suppresses TPA-induced matrix metalloproteinase-9 expression through the inhibition of MAPK pathways in oral cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Movement; Cell Survival; Down-Regulation; Enzyme Activation; Head and Neck Neoplasms; Humans; JNK Mitogen-Activated Protein Kinases; Matrix Metalloproteinase 9; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mouth Neoplasms; Neoplasm Invasiveness; Neoplasm Metastasis; Resveratrol; Signal Transduction; Squamous Cell Carcinoma of Head and Neck; Stilbenes; Tetradecanoylphorbol Acetate; Tongue Neoplasms | 2015 |
Riboflavin as adjuvant with cisplatin: study in mouse skin cancer model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Antioxidants; Body Weight; Carcinoma, Squamous Cell; Cisplatin; Drug Screening Assays, Antitumor; Drug Synergism; Drug Therapy, Combination; Glutathione; Kidney; Liver; Male; Malondialdehyde; Mice; Photosensitizing Agents; Random Allocation; Riboflavin; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2015 |
Mouse models of nonmelanoma skin cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cell Culture Techniques; DNA; Epidermis; Humans; Keratinocytes; Mice; Skin Neoplasms; Staining and Labeling; Tamoxifen; Tetradecanoylphorbol Acetate | 2015 |
TGF-β promotes heterogeneity and drug resistance in squamous cell carcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cisplatin; Drug Resistance, Neoplasm; Female; Gene Expression Profiling; Glutathione; Head and Neck Neoplasms; Heterografts; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Neoplastic Stem Cells; NF-E2-Related Factor 2; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta | 2015 |
Ectopic expression of protein kinase C-β sensitizes head and neck squamous cell carcinoma to diterpene esters.
Topics: Carcinoma, Squamous Cell; Cell Survival; Diterpenes; Head and Neck Neoplasms; Humans; Isoenzymes; Protein Kinase C beta; Squamous Cell Carcinoma of Head and Neck; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2015 |
Crosstalk between Desmoglein 2 and Patched 1 accelerates chemical-induced skin tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma in Situ; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cell Division; Cocarcinogenesis; Dermis; Desmoglein 2; Epidermis; Gene Knock-In Techniques; Genes, Reporter; Genetic Predisposition to Disease; Genotype; Hair Follicle; Hedgehog Proteins; Hyperplasia; Keratinocytes; Mice; Mice, Transgenic; Papilloma; Patched Receptors; Patched-1 Receptor; Receptors, Cell Surface; Signal Transduction; Skin Neoplasms; Stromal Cells; Tetradecanoylphorbol Acetate; Time Factors | 2015 |
12-O-Tetradecanoylphorbol-13-Acetate Induces Up-Regulated Transcription of Variant 1 but Not Variant 2 of VIL2 in Esophageal Squamous Cell Carcinoma Cells via ERK1/2/AP-1/Sp1 Signaling.
Topics: Alternative Splicing; Binding Sites; Butadienes; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Movement; Codon, Initiator; Cytoskeletal Proteins; DNA; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Humans; MAP Kinase Signaling System; Nitriles; Promoter Regions, Genetic; Tetradecanoylphorbol Acetate; Up-Regulation | 2015 |
Genetic deletion of TNFα inhibits ultraviolet radiation-induced development of cutaneous squamous cell carcinomas in PKCε transgenic mice via inhibition of cell survival signals.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogenesis; Carcinogens; Carcinoma, Squamous Cell; Cell Survival; Female; Male; Mice; Mice, Knockout; Mice, Transgenic; Protein Kinase C-epsilon; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Ultraviolet Rays | 2016 |
Fractionation of a tumor-initiating UV dose introduces DNA damage-retaining cells in hairless mouse skin and renders subsequent TPA-promoted tumors non-regressing.
Topics: Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; DNA Damage; Epidermis; Female; Hyperplasia; Immunoenzyme Techniques; Male; Mice; Mice, Hairless; Mutation; Real-Time Polymerase Chain Reaction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53; Ultraviolet Rays | 2016 |
MET signaling in keratinocytes activates EGFR and initiates squamous carcinogenesis.
Topics: Animals; Carcinoma, Squamous Cell; ErbB Receptors; Gene Expression Regulation, Neoplastic; Humans; Keratinocytes; Mice; Proto-Oncogene Proteins c-met; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2016 |
Elevated VEGF-D Modulates Tumor Inflammation and Reduces the Growth of Carcinogen-Induced Skin Tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Flow Cytometry; Lymph Nodes; Lymphangiogenesis; Lymphatic Metastasis; Lymphatic Vessels; Lymphocyte Count; Macrophages; Mast Cells; Mice; Mice, Knockout; Polymerase Chain Reaction; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Vascular Endothelial Growth Factor D | 2016 |
Arsenic exposure in utero exacerbates skin cancer response in adulthood with contemporaneous distortion of tumor stem cell dynamics.
Topics: Animals; Antigens, CD34; Arsenic; Carcinoma, Squamous Cell; Cell Cycle Proteins; Female; Fetus; Genes, ras; Mice; Neoplastic Stem Cells; Neuropeptides; Pregnancy; Proteins; rac GTP-Binding Proteins; rac1 GTP-Binding Protein; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2008 |
Promotion of mouse two-stage skin carcinogenesis by diacylglycerol-rich edible oil.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Diglycerides; Fatty Acids; Female; Fluocinolone Acetonide; Linoleic Acid; Mice; Oils; Oleic Acid; Protein Kinase C; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2009 |
A novel Src kinase inhibitor reduces tumour formation in a skin carcinogenesis model.
Topics: Adult; Aged; Animals; Anticarcinogenic Agents; Benzodioxoles; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Disease Models, Animal; Female; Humans; Keratinocytes; Keratosis; Male; Mice; Middle Aged; Papilloma; Precancerous Conditions; Quinazolines; Skin Neoplasms; src-Family Kinases; Tetradecanoylphorbol Acetate | 2009 |
Hypoxia-inducible factor-1alpha suppresses squamous carcinogenic progression and epithelial-mesenchymal transition.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Cycle Proteins; Disease Progression; Epithelial Cells; Hypoxia-Inducible Factor 1, alpha Subunit; Intracellular Signaling Peptides and Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Selenium-Binding Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transfection | 2009 |
Photodynamic therapy with 5-aminolevulinic acid and diamino acid derivatives of protoporphyrin IX reduces papillomas in mice without eliminating transformation into squamous cell carcinoma of the skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aminolevulinic Acid; Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Kaplan-Meier Estimate; Mice; Mice, Inbred Strains; Papilloma; Photochemotherapy; Photosensitizing Agents; Protoporphyrins; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2009 |
Marked inhibition of growth and invasive parameters of head and neck squamous carcinoma FaDu by a nutrient mixture.
Topics: Administration, Oral; Amino Acids; Animals; Apoptosis; Ascorbic Acid; Camellia sinensis; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Survival; Complementary Therapies; Food; Head and Neck Neoplasms; Humans; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Nude; Neoplasm Invasiveness; Plant Extracts; Tetradecanoylphorbol Acetate; Xenograft Model Antitumor Assays | 2009 |
All-trans retinoic acid suppresses Stat3 signaling during skin carcinogenesis.
Topics: Animals; Antineoplastic Agents; Blotting, Western; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Extracellular Signal-Regulated MAP Kinases; Female; Immunohistochemistry; MAP Kinase Kinase Kinases; Mice; Mice, Inbred SENCAR; Mice, Transgenic; raf Kinases; Signal Transduction; Skin Neoplasms; STAT3 Transcription Factor; Tetradecanoylphorbol Acetate; Tretinoin | 2009 |
The immunosuppressive surface ligand CD200 augments the metastatic capacity of squamous cell carcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, CD; Antigens, Surface; Carcinoma, Squamous Cell; Cell Growth Processes; Female; Gene Knockdown Techniques; Humans; Keratinocytes; Membrane Glycoproteins; Mice; Orexin Receptors; Receptors, Cell Surface; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2010 |
The tumor-suppressive function of Connexin43 in keratinocytes is mediated in part via interaction with caveolin-1.
Topics: Animals; Anti-Ulcer Agents; Blotting, Western; Carbenoxolone; Carcinogens; Carcinoma, Squamous Cell; Caveolin 1; Cell Communication; Cell Proliferation; Connexin 43; Epidermal Cells; Epidermal Growth Factor; Epidermis; Epithelial Cells; Fluorescent Antibody Technique; Gap Junctions; Green Fluorescent Proteins; Humans; Immunoprecipitation; Keratinocytes; Mesoderm; Neoplasm Invasiveness; Rats; RNA, Small Interfering; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta1 | 2010 |
The skin cancer chemotherapeutic agent ingenol-3-angelate (PEP005) is a substrate for the epidermal multidrug transporter (ABCB1) and targets tumor vasculature.
Topics: Administration, Topical; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Squamous Cell; Cell Line, Tumor; Diterpenes; Drug Eruptions; Enzyme Activation; Humans; Keratinocytes; Melanoma, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; Neovascularization, Pathologic; Protein Binding; Protein Kinase C; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2010 |
Cocarcinogenic effect of capsaicin involves activation of EGFR signaling but not TRPV1.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Capsaicin; Carcinoma, Squamous Cell; Cell Line, Tumor; Cocarcinogenesis; Cyclooxygenase 2; Drug Synergism; Enzyme Activation; ErbB Receptors; Female; Humans; Male; Mice; Mice, Knockout; Signal Transduction; Skin Neoplasms; src-Family Kinases; Tetradecanoylphorbol Acetate; TRPV Cation Channels | 2010 |
CYLD inhibits tumorigenesis and metastasis by blocking JNK/AP1 signaling at multiple levels.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Cysteine Endopeptidases; Deubiquitinating Enzyme CYLD; Disease Progression; Epidermal Cells; Epidermis; Humans; Hyperplasia; Immunoblotting; Immunoprecipitation; JNK Mitogen-Activated Protein Kinases; Lymphatic Metastasis; Mice; Mice, Transgenic; Mutation; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Tumor Cells, Cultured; Tumor Suppressor Proteins; Ubiquitination | 2011 |
Potential O-acyl-substituted (-)-Epicatechin gallate prodrugs as inhibitors of DMBA/TPA-induced squamous cell carcinoma of skin in Swiss albino mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Squamous Cell; Catechin; Female; Humans; Hydrolysis; Mice; Prodrugs; Skin; Skin Neoplasms; Solubility; Tea; Tetradecanoylphorbol Acetate | 2011 |
The number of CD161 positive Th17 cells are decreased in head and neck cancer patients.
Topics: Aged; Brefeldin A; Carcinoma, Squamous Cell; Culture Media, Conditioned; Head and Neck Neoplasms; Humans; Ionomycin; Leukocytes, Mononuclear; Lymph Nodes; Lymphocyte Activation; Middle Aged; Neoplasm Metastasis; NK Cell Lectin-Like Receptor Subfamily B; Tetradecanoylphorbol Acetate; Th17 Cells | 2011 |
CXCR3 enhances a T-cell-dependent epidermal proliferative response and promotes skin tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cell Proliferation; Cell Transformation, Neoplastic; Epidermis; Humans; Lymphocytes, Tumor-Infiltrating; Methylcholanthrene; Mice; Mice, Mutant Strains; Receptors, CXCR3; Skin Neoplasms; T-Lymphocytes; Tetradecanoylphorbol Acetate | 2011 |
E6 and E7 from beta HPV38 cooperate with ultraviolet light in the development of actinic keratosis-like lesions and squamous cell carcinoma in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alphapapillomavirus; Animals; Carcinogens; Carcinoma, Squamous Cell; Cyclin-Dependent Kinase Inhibitor p21; Epidermis; Humans; Keratinocytes; Keratosis, Actinic; Mice; Mice, Transgenic; Oncogene Proteins, Viral; Papillomavirus Infections; Skin Neoplasms; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 2011 |
Effects of heme oxygenase-1 on induction and development of chemically induced squamous cell carcinoma in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Female; Heme Oxygenase-1; Mice; Mice, Inbred Strains; Mice, Knockout; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2011 |
Loss of Trop2 promotes carcinogenesis and features of epithelial to mesenchymal transition in squamous cell carcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Neoplasm; Carcinoma, Squamous Cell; Cell Adhesion Molecules; Cell Dedifferentiation; Cell Line, Tumor; Cell Transformation, Neoplastic; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Keratinocytes; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2011 |
Human epithelial carcinoma cytotoxicity and inhibition of DMBA/TPA induced squamous cell carcinoma in Balb/c mice by Acacia catechu heartwood.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acacia; Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Glutathione; Humans; Lipid Peroxidation; Liver; Mice; Mice, Inbred BALB C; Plant Preparations; Random Allocation; Skin Neoplasms; Superoxide Dismutase; Tetradecanoylphorbol Acetate | 2011 |
Manganese superoxide dismutase is a p53-regulated gene that switches cancers between early and advanced stages.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Cocarcinogenesis; Disease Progression; Enhancer Elements, Genetic; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Genes, Reporter; Genes, Synthetic; Humans; Mice; Mice, Transgenic; Neoplasm Proteins; Papilloma; Promoter Regions, Genetic; Recombinant Fusion Proteins; Skin Neoplasms; Sp1 Transcription Factor; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Suppressor Protein p53 | 2011 |
Angiopoietin-like protein 2 is an important facilitator of inflammatory carcinogenesis and metastasis.
Topics: Angiopoietin-Like Protein 2; Angiopoietin-like Proteins; Angiopoietins; Animals; Carcinogens; Carcinoma, Squamous Cell; Epithelial-Mesenchymal Transition; Female; Gene Expression; Immunoblotting; Immunohistochemistry; Inflammation; Inflammation Mediators; Kaplan-Meier Estimate; Lymph Nodes; Lymphangiogenesis; Male; Mice; Mice, Knockout; Mice, Transgenic; Neoplasm Metastasis; Neovascularization, Pathologic; Reverse Transcriptase Polymerase Chain Reaction; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2011 |
Kalopanaxsaponin A inhibits the invasion of human oral squamous cell carcinoma by reducing metalloproteinase-9 mRNA stability and protein trafficking.
Topics: Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Survival; Female; Humans; Matrix Metalloproteinase 9; Mice; Mice, Nude; Mouth Neoplasms; Neoplasm Invasiveness; Oleanolic Acid; Protein Transport; RNA, Messenger; Saponins; Tetradecanoylphorbol Acetate; Tumor Burden; Xenograft Model Antitumor Assays | 2012 |
Epidermal α6β4 integrin stimulates the influx of immunosuppressive cells during skin tumor promotion.
Topics: Animals; Antigens, Surface; Carcinogens; Carcinoma, Squamous Cell; Chemokine CXCL5; Epidermis; Gene Expression; Humans; Inflammation Mediators; Integrin alpha6beta4; Keratinocytes; Lymphocyte Activation; Macrophage Colony-Stimulating Factor; Mice; Mice, Transgenic; Myeloid Cells; Orexin Receptors; Receptors, Cell Surface; Recombinant Proteins; Skin Neoplasms; T-Lymphocytes; T-Lymphocytes, Regulatory; Tetradecanoylphorbol Acetate; Tumor Microenvironment | 2012 |
Deficiency of the Kruppel-like factor KLF4 correlates with increased cell proliferation and enhanced skin tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cell Adhesion; Cell Differentiation; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; Female; Gene Expression Regulation, Neoplastic; Humans; Keratinocytes; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Mice; Mice, Transgenic; RNA Interference; RNA, Small Interfering; Skin Neoplasms; Tamoxifen; Tetradecanoylphorbol Acetate | 2012 |
The orphan receptor GPR55 drives skin carcinogenesis and is upregulated in human squamous cell carcinomas.
Topics: Animals; Carcinoma, Squamous Cell; Cell Proliferation; Gene Expression Regulation, Neoplastic; Humans; Inflammation; Laryngeal Neoplasms; Mice; Mice, Knockout; Mouth Neoplasms; Protein Disulfide-Isomerases; Receptors, Cannabinoid; Receptors, G-Protein-Coupled; Reference Values; Skin Neoplasms; Tetradecanoylphorbol Acetate; Up-Regulation | 2013 |
Nexrutine(R) inhibits tumorigenesis in mouse skin and induces apoptotic cell death in human squamous carcinoma A431 and human melanoma A375 cells.
Topics: Animals; Anti-Inflammatory Agents; Anticarcinogenic Agents; Apoptosis; Carcinoma, Squamous Cell; Cell Line, Tumor; Humans; Melanoma; Mice; Plant Extracts; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2012 |
A transposon-based analysis of gene mutations related to skin cancer development.
Topics: Animals; Carcinogens; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Carrier Proteins; Cell Transformation, Neoplastic; DNA Mutational Analysis; DNA Transposable Elements; Genes, ras; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Humans; Intracellular Signaling Peptides and Proteins; Keratin-15; Keratin-5; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Transgenic; Mutation; Nuclear Proteins; Promoter Regions, Genetic; Receptor, Notch1; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transposases | 2013 |
Topical 5-fluorouracil elicits regressions of BRAF inhibitor-induced cutaneous squamous cell carcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Antineoplastic Agents; Carcinogens; Carcinoma, Squamous Cell; Cell Line; Cell Proliferation; Fluorouracil; Humans; Imidazoles; Indoles; Melanoma; Mice; Oximes; Proto-Oncogene Proteins B-raf; Skin Neoplasms; Sulfonamides; Tetradecanoylphorbol Acetate; Vemurafenib | 2013 |
Expression profiles of cortisol-inactivating enzyme, 11β-hydroxysteroid dehydrogenase-2, in human epidermal tumors and its role in keratinocyte proliferation.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; 11-beta-Hydroxysteroid Dehydrogenase Type 2; Adolescent; Adult; Aged; Animals; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cell Proliferation; Disease Models, Animal; Epidermis; Female; Gene Expression Profiling; Gene Expression Regulation, Enzymologic; Humans; Hydrocortisone; Keratinocytes; Keratosis, Seborrheic; Male; Mice; Mice, Inbred C57BL; Middle Aged; Tetradecanoylphorbol Acetate; Young Adult | 2013 |
Calcium regulation of matrix metalloproteinase-mediated migration in oral squamous cell carcinoma cells.
Topics: Calcium; Carcinoma, Squamous Cell; Cell Movement; Enzyme Activation; Enzyme Precursors; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinases, Membrane-Associated; Metalloendopeptidases; Mouth Neoplasms; Tetradecanoylphorbol Acetate; Tissue Inhibitor of Metalloproteinase-2; Tumor Cells, Cultured | 2002 |
Transgenic cyclooxygenase-2 overexpression sensitizes mouse skin for carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoma; Animals; Carcinogens; Carcinoma, Squamous Cell; Celecoxib; Cocarcinogenesis; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Disease Models, Animal; Gene Expression; Isoenzymes; Mice; Mice, Transgenic; Papilloma; Phenotype; Precancerous Conditions; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Pyrazoles; Skin; Skin Neoplasms; Sulfonamides; Tetradecanoylphorbol Acetate | 2002 |
Matrix metalloproteinase-19 is expressed by proliferating epithelium but disappears with neoplastic dedifferentiation.
Topics: Blotting, Northern; Blotting, Western; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cell Differentiation; Cell Division; Cell Transformation, Neoplastic; Down-Regulation; Female; Fibroblasts; Humans; Immunoenzyme Techniques; Keratinocytes; Male; Matrix Metalloproteinases, Secreted; Metalloendopeptidases; Middle Aged; RNA, Messenger; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2003 |
A 60 Hz magnetic field does not affect the incidence of squamous cell carcinomas in SENCAR mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Back; Carcinogens; Carcinoma, Squamous Cell; Cocarcinogenesis; Drug Tolerance; Electricity; Electromagnetic Fields; Mice; Mice, Inbred SENCAR; Neoplasms, Radiation-Induced; Radiation Tolerance; Reference Values; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2003 |
Effector CD8+CD45RO-CD27-T cells have signalling defects in patients with squamous cell carcinoma of the head and neck.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Annexin A5; Apoptosis; Carcinogens; Carcinoma, Squamous Cell; Case-Control Studies; CD8-Positive T-Lymphocytes; Cohort Studies; Female; Flow Cytometry; Head and Neck Neoplasms; Humans; Immunologic Memory; Interferon-gamma; Ionomycin; Ionophores; Leukocyte Common Antigens; Male; Middle Aged; Receptors, Antigen, T-Cell; T-Lymphocyte Subsets; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor Receptor Superfamily, Member 7 | 2003 |
Expression of enhancing factor/phospholipase A2 in skin results in abnormal epidermis and increased sensitivity to chemical carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Abnormalities, Multiple; Animals; Carcinogens; Carcinoma, Squamous Cell; Epidermis; Fibrosarcoma; Genetic Predisposition to Disease; Genotype; Group II Phospholipases A2; Humans; Keratins; Mice; Mice, Transgenic; Neoplasms, Basal Cell; Papilloma; Phenotype; Phospholipases A; Promoter Regions, Genetic; Recombinant Fusion Proteins; Skin; Skin Neoplasms; Tail; Tetradecanoylphorbol Acetate; Transgenes; Vibrissae | 2003 |
Interplay between proximal and distal promoter elements is required for squamous differentiation marker induction in the bronchial epithelium: role for ESE-1, Sp1, and AP-1 proteins.
Topics: Base Sequence; Binding Sites; Biomarkers, Tumor; Bronchial Neoplasms; Carcinogens; Carcinoma, Squamous Cell; Cell Differentiation; Cell Nucleus; Cornified Envelope Proline-Rich Proteins; DNA-Binding Proteins; Epithelial Cells; Epithelium; Gene Expression Regulation, Neoplastic; Humans; JNK Mitogen-Activated Protein Kinases; Membrane Proteins; Mitogen-Activated Protein Kinases; Models, Genetic; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Oligonucleotides; Promoter Regions, Genetic; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ets; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sp1 Transcription Factor; Tetradecanoylphorbol Acetate; Time Factors; Trans-Activators; Transcription Factor AP-1; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transfection; Tumor Cells, Cultured; Up-Regulation | 2003 |
SCCA2-like serpins mediate genetic predisposition to skin tumors.
Topics: Adult; Aged; Animals; Antigens, Neoplasm; Carcinoma, Squamous Cell; Cell Division; Genetic Predisposition to Disease; Humans; Immunohistochemistry; Male; Mice; Mice, Nude; Middle Aged; Oligonucleotide Array Sequence Analysis; Serpins; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transfection | 2003 |
E2F modulates keratinocyte squamous differentiation: implications for E2F inhibition in squamous cell carcinoma.
Topics: Binding Sites; Biomarkers; Carcinoma, Squamous Cell; Cell Cycle Proteins; Cell Differentiation; Cell Division; DNA; DNA-Binding Proteins; E2F Transcription Factors; E2F1 Transcription Factor; Epidermis; Frameshift Mutation; Gene Expression; Humans; Keratinocytes; Point Mutation; Protein Isoforms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Transcription Factors; Transcriptional Activation; Transfection; Tumor Cells, Cultured | 2003 |
IL-1 alpha, innate immunity, and skin carcinogenesis: the effect of constitutive expression of IL-1 alpha in epidermis on chemical carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; DNA-Binding Proteins; Epidermis; Female; Humans; Immunity, Innate; Interleukin-1; Keratin-14; Keratins; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Nuclear Proteins; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transgenes | 2003 |
Inhibition of the development of metastatic squamous cell carcinoma in protein kinase C epsilon transgenic mice by alpha-difluoromethylornithine accompanied by marked hair follicle degeneration and hair loss.
Topics: Administration, Oral; Alopecia; Animals; Benz(a)Anthracenes; Carcinogens; Carcinoma, Squamous Cell; Cocarcinogenesis; Eflornithine; Enzyme Inhibitors; Epidermis; Hair Follicle; Isoenzymes; Mice; Mice, Transgenic; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Polyamines; Protein Kinase C; Protein Kinase C-epsilon; Putrescine; Recombinant Fusion Proteins; Skin Neoplasms; Skin Ulcer; Tetradecanoylphorbol Acetate | 2003 |
Difference in responsiveness of human esophageal squamous cell carcinoma lines to epidermal growth factor for MMP-7 expression.
Topics: Carcinogens; Carcinoma, Squamous Cell; DNA-Binding Proteins; Epidermal Growth Factor; Esophageal Neoplasms; Gene Expression Regulation, Enzymologic; Hepatocyte Nuclear Factor 1; Hepatocyte Nuclear Factor 1-alpha; Hepatocyte Nuclear Factor 1-beta; Humans; Luciferases; Lymphoid Enhancer-Binding Factor 1; Matrix Metalloproteinase 7; Mutagenesis, Site-Directed; Mutation; Nuclear Proteins; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Sequence Deletion; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transfection; Tumor Cells, Cultured | 2003 |
Targeted expression of c-Src in epidermal basal cells leads to enhanced skin tumor promotion, malignant progression, and metastasis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Amino Acid Sequence; Animals; Carcinoma, Squamous Cell; CSK Tyrosine-Protein Kinase; Female; Male; Mice; Mice, Transgenic; Molecular Sequence Data; Neoplasm Metastasis; Protein-Tyrosine Kinases; Skin; Skin Neoplasms; src-Family Kinases; Tetradecanoylphorbol Acetate | 2003 |
Protein kinase Cepsilon is linked to 12-O-tetradecanoylphorbol-13-acetate-induced tumor necrosis factor-alpha ectodomain shedding and the development of metastatic squamous cell carcinoma in protein kinase Cepsilon transgenic mice.
Topics: Animals; Carcinogens; Carcinoma, Squamous Cell; Female; Keratinocytes; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Pentoxifylline; Protein Kinase C; Protein Kinase C-epsilon; Protein Structure, Tertiary; Reactive Oxygen Species; Signal Transduction; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2003 |
The effect of nitric oxide on cyclooxygenase-2 (COX-2) overexpression in head and neck cancer cell lines.
Topics: Carcinoma, Squamous Cell; Cyclooxygenase 1; Cyclooxygenase 2; Dactinomycin; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Humans; Isoenzymes; Membrane Proteins; Nitric Oxide; Nitric Oxide Donors; Prostaglandin-Endoperoxide Synthases; Reverse Transcriptase Polymerase Chain Reaction; S-Nitroso-N-Acetylpenicillamine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2003 |
RING protein Trim32 associated with skin carcinogenesis has anti-apoptotic and E3-ubiquitin ligase properties.
Topics: Animals; Apoptosis; Carcinoma, Squamous Cell; Cell Division; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; Genes, p53; Head and Neck Neoplasms; Humans; Keratinocytes; Mice; Mice, Nude; RNA, Messenger; Skin Neoplasms; Skin Transplantation; Tetradecanoylphorbol Acetate; Transcription Factors; Transduction, Genetic; Tripartite Motif Proteins; Tumor Necrosis Factor-alpha; Ubiquitin-Protein Ligases; Ultraviolet Rays | 2004 |
Free radical generating agents lead to the rapid progression of benign skin tumors to carcinoma in iron-overloaded mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzene Derivatives; Benzoyl Peroxide; Carcinogens; Carcinoma, Squamous Cell; Disease Progression; Female; Free Radicals; Hydrogen Peroxide; Iron; Iron Overload; Iron-Dextran Complex; Mice; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2004 |
Enzymatic synthesis of tea theaflavin derivatives and their anti-inflammatory and cytotoxic activities.
Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acid; Biflavonoids; Biochemistry; Carcinoma, Squamous Cell; Catechin; Cell Division; Cells, Cultured; Colonic Neoplasms; Drug Evaluation, Preclinical; Ear Diseases; Edema; Esophageal Neoplasms; Female; Horseradish Peroxidase; Humans; Macrophages; Mice; Mice, Inbred Strains; Structure-Activity Relationship; Tea; Tetradecanoylphorbol Acetate; Toxicity Tests; Tumor Cells, Cultured | 2004 |
Augmentation of chemotherapy-induced cytokine production by expression of the platelet-activating factor receptor in a human epithelial carcinoma cell line.
Topics: Adjuvants, Immunologic; Antineoplastic Agents; Antioxidants; Carcinoma, Squamous Cell; Chromans; Cytokines; Etoposide; Humans; Interleukin-8; KB Cells; Mitomycin; NF-kappa B; Oxidative Stress; Phospholipid Ethers; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Transduction, Genetic | 2004 |
Early detection of alterations associated to oral cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Analysis of Variance; Animals; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cheek; Cricetinae; Hyperplasia; Mesocricetus; Mouth Neoplasms; Neoplasms, Radiation-Induced; Nucleolus Organizer Region; Silver Staining; Statistics, Nonparametric; Tetradecanoylphorbol Acetate | 2000 |
A novel ATX-S10(Na) photodynamic therapy for human skin tumors and benign hyperproliferative skin.
Topics: Animals; Bowen's Disease; Carcinogens; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Disease Models, Animal; Female; Humans; Laser Therapy; Mice; Mice, Hairless; Mice, Inbred BALB C; Mice, SCID; Neoplasm Transplantation; Ointments; Photochemotherapy; Porphyrins; Psoriasis; Radiation-Sensitizing Agents; Skin; Skin Diseases; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transplantation, Heterologous | 2004 |
Global analysis of altered gene expressions during the process of esophageal squamous cell carcinogenesis in the rat: a study combined with a laser microdissection and a cDNA microarray.
Topics: Animals; Carcinoma, Squamous Cell; Cocarcinogenesis; Esophageal Neoplasms; Gene Expression Profiling; Genetic Predisposition to Disease; Lasers; Male; Microdissection; Nitrosamines; Oligonucleotide Array Sequence Analysis; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Neoplasm; Tetradecanoylphorbol Acetate | 2005 |
Prostaglandin E receptor EP3 deficiency modifies tumor outcome in mouse two-stage skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cadherins; Carcinoma, Squamous Cell; Female; Incidence; Keratoacanthoma; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP3 Subtype; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Skin Neoplasms; Tetradecanoylphorbol Acetate; Treatment Outcome | 2005 |
Reduced excision repair cross-complementing 1 expression associates with enhanced papilloma formation and fibroblast transformation after genetic disruption of secreted protein acidic and rich in cysteine.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cells, Cultured; DNA Adducts; DNA-Binding Proteins; Embryo, Mammalian; Endonucleases; Female; Fibroblasts; Gene Expression; Genotype; Male; Mice; Mice, Inbred Strains; Mice, Knockout; Osteonectin; Papilloma; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Skin; Tetradecanoylphorbol Acetate; Time Factors | 2005 |
Regulation of the release and function of tumor cell-derived soluble CD44.
Topics: Antigens, CD; Carcinoma, Squamous Cell; Cell Line, Tumor; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Hyaluronan Receptors; Hyaluronic Acid; Lung Neoplasms; Metalloproteases; Recombinant Proteins; Tetradecanoylphorbol Acetate | 2005 |
Methylation of the O6-methylguanine-DNA methyltransferase promoter suppresses expression in mouse skin tumors and varies with the tumor induction protocol.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Diterpenes; DNA Methylation; Gene Expression Regulation, Neoplastic; Genes, ras; Humans; Methylnitronitrosoguanidine; Mice; Mutation; O(6)-Methylguanine-DNA Methyltransferase; Papilloma; Promoter Regions, Genetic; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2006 |
Early epidermal destruction with subsequent epidermal hyperplasia is a unique feature of the papilloma-independent squamous cell carcinoma phenotype in PKCepsilon overexpressing transgenic mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cell Death; Cell Differentiation; Cell Proliferation; Chemotaxis, Leukocyte; Cocarcinogenesis; Disease Models, Animal; Epidermis; Female; Hair Follicle; Hyperplasia; Keratin-10; Keratinocytes; Keratins; Mice; Mice, Transgenic; Neutrophils; Phenotype; Precancerous Conditions; Protein Kinase C-epsilon; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 2005 |
Skin tumorigenic potential of aflatoxin B1 in mice.
Topics: Administration, Topical; Aflatoxin B1; Animals; Carcinogens; Carcinoma, Squamous Cell; Dose-Response Relationship, Drug; Female; Glutathione Transferase; Lipid Peroxidation; Liver; Liver Neoplasms; Mice; Poisons; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2006 |
[TPA increases cell proliferation of HEp-2 cell line in vitro].
Topics: Carcinogens; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Humans; Laryngeal Neoplasms; Tetradecanoylphorbol Acetate | 2005 |
Deregulated minichromosomal maintenance protein MCM7 contributes to oncogene driven tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biomarkers, Tumor; Carcinogens; Carcinoma, Squamous Cell; Cell Cycle Proteins; Cell Proliferation; Cell Transformation, Neoplastic; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; Genes, ras; Humans; Mice; Mice, Transgenic; Minichromosome Maintenance Complex Component 7; Mutation; Neoplasm Proteins; Neoplasms, Experimental; Nuclear Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2006 |
A novel aspartic proteinase-like gene expressed in stratified epithelia and squamous cell carcinoma of the skin.
Topics: Amino Acid Sequence; Animals; Aspartic Acid Endopeptidases; Carcinoma, Squamous Cell; Cell Differentiation; Cell Line, Tumor; Dexamethasone; Epidermis; Epithelium; Female; Gene Expression Regulation, Developmental; Gene Expression Regulation, Neoplastic; Genes, fos; Humans; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factor AP-1 | 2006 |
Overexpression of the prostaglandin E2 receptor EP2 results in enhanced skin tumor development.
Topics: Animals; Animals, Newborn; Bromodeoxyuridine; Carcinoma, Squamous Cell; Cattle; Cell Culture Techniques; Cell Proliferation; Female; Humans; Hyperplasia; Inflammation; Keratinocytes; Keratins; Mice; Mice, Transgenic; Neovascularization, Pathologic; Polymerase Chain Reaction; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Skin Neoplasms; Tetradecanoylphorbol Acetate; Up-Regulation | 2006 |
[The establishment of B(a)P and TPA transformed cell line and its biological characteristics].
Topics: Benzo(a)pyrene; Carcinogens; Carcinoma, Squamous Cell; Cell Line; Cell Line, Transformed; Cell Line, Tumor; Cell Transformation, Viral; Cells, Cultured; Epithelial Cells; Humans; Mouth Neoplasms; Neoplasms, Experimental; Tetradecanoylphorbol Acetate; Vimentin | 2006 |
Expression profile of skin papillomas with high cancer risk displays a unique genetic signature that clusters with squamous cell carcinomas and predicts risk for malignant conversion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biomarkers, Tumor; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Female; Gene Expression Profiling; Immunity, Cellular; Immunophenotyping; Mice; Mice, Inbred SENCAR; Oligonucleotide Array Sequence Analysis; Papilloma; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; Risk Factors; RNA, Messenger; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2007 |
Indole-3-carbinol - induced growth inhibition can be converted to a cytotoxic response in the presence of TPA+Ca(2+) in squamous cell carcinoma cell lines.
Topics: Calcium; Carcinoma, Squamous Cell; Cell Differentiation; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Epithelial Cells; Flow Cytometry; Growth; Humans; Indoles; Infant, Newborn; Keratinocytes; Male; Skin; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured | 2007 |
The role of glycogen synthase kinase 3beta in the transformation of epidermal cells.
Topics: Animals; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Enzyme Activation; Epidermal Growth Factor; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Male; Mice; Mice, Inbred BALB C; Oncogene Protein v-akt; Phosphatidylinositol 3-Kinases; Protein Kinase C; Signal Transduction; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transfection | 2007 |
Cdk2 deficiency decreases ras/CDK4-dependent malignant progression, but not myc-induced tumorigenesis.
Topics: Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Disease Progression; Enzyme Activation; Female; Male; Mice; Mice, Transgenic; Proto-Oncogene Proteins c-myc; ras Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2007 |
Increased cytokine secretion in head and neck cancer upon p38 mitogen-activated protein kinase activation.
Topics: Carcinogens; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Enzyme Activation; Head and Neck Neoplasms; Humans; Interleukin-6; Interleukin-8; MAP Kinase Signaling System; p38 Mitogen-Activated Protein Kinases; Tetradecanoylphorbol Acetate | 2007 |
p19/Arf and p53 suppress sentinel lymph node lymphangiogenesis and carcinoma metastasis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; B-Lymphocytes; Carcinoma, Squamous Cell; Cell Proliferation; Chemotaxis, Leukocyte; Cyclin-Dependent Kinase Inhibitor p16; Lymph Nodes; Lymphangiogenesis; Lymphatic Metastasis; Macrophages; Mice; Mice, Transgenic; Neovascularization, Pathologic; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53; Vascular Endothelial Growth Factor A | 2008 |
Differential tumor biology effects of double-initiation in a mouse skin chemical carcinogenesis model comparing wild type versus protein kinase Cepsilon overexpression mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinoma, Squamous Cell; Female; Genes, ras; Mice; Mice, Transgenic; Mutation; Papilloma; Protein Kinase C-epsilon; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2007 |
Tumor promoter phorbol 12-myristate 13-acetate inhibits mitogen-stimulated Na+/H+ exchange in human epidermoid carcinoma A431 cells.
Topics: Carcinoma, Squamous Cell; Carrier Proteins; Cell Line; Culture Media; Epidermal Growth Factor; Humans; Hydrogen-Ion Concentration; Mannitol; Mitogens; Phorbols; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate; Vanadates; Vanadium | 1984 |
Mechanisms of initiation and promotion in mouse epidermis.
Topics: Acyltransferases; Animals; Animals, Newborn; Carcinogens; Carcinoma, Squamous Cell; Cell Division; Cells, Cultured; Female; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transglutaminases | 1984 |
Simultaneous appearance of keratin modifications and gamma-glutamyltransferase activity as indicators of tumor progression in mouse skin papillomas.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acyltransferases; Animals; Carcinoma, Squamous Cell; Female; Histocytochemistry; Keratins; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transglutaminases | 1983 |
A subpopulation of cultured human keratinocytes which is resistant to the induction of terminal differentiation-related changes by phorbol, 12-myristate, 13-acetate: evidence for an increase in the resistant population following transformation.
Topics: Animals; Carcinoma, Squamous Cell; Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Child; Cholera Toxin; Epidermal Growth Factor; Female; Fetus; Humans; Hydrocortisone; Keratins; Male; Mice; Phorbols; Pregnancy; Simian virus 40; Skin; Skin Physiological Phenomena; Tetradecanoylphorbol Acetate | 1983 |
Non-promoting hyperplasiogenic agents do not mimic the effects of phorbol, 12-myristate, 13-acetate on terminal differentiation of normal and transformed human keratinocytes.
Topics: Alkynes; Calcimycin; Carcinoma, Squamous Cell; Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Clone Cells; Humans; Hyperplasia; Keratins; Phorbols; Skin; Tetradecanoylphorbol Acetate | 1984 |
Differential effects of complete and second-stage tumour promoters in normal but not transformed human and mouse keratinocytes.
Topics: Carcinogens; Carcinoma, Squamous Cell; Cell Line; Cell Transformation, Neoplastic; Diterpenes; Drug Resistance; Epidermal Cells; Epidermis; Humans; Keratins; Phorbol Esters; Phorbols; Terpenes; Tetradecanoylphorbol Acetate | 1984 |
Activation of calcium and phospholipid-dependent protein kinase by epidermal growth factor (EGF) in A431 cells: attenuation by 12-0-tetradecanoylphorbol-13-acetate (TPA).
Topics: Carcinoma, Squamous Cell; Cell Line; Diglycerides; Drug Antagonism; Epidermal Growth Factor; Humans; Kinetics; Phorbols; Phospholipids; Protein Kinase C; Protein Kinases; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1982 |
Conversion of herpetic lesions to malignancy by ultraviolet exposure and promoter application.
Topics: Animals; Antibodies, Viral; Carcinoma, Squamous Cell; Herpes Labialis; Lip; Lip Neoplasms; Male; Mice; Neutralization Tests; Papilloma; Simplexvirus; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 1981 |
Effect of 12-O-tetradecanoylphorbol-13-acetate (TPA) on the growth inhibitory and increased phosphatidylinositol (PI) responses induced by epidermal growth factor (EGF) in A431 cells.
Topics: Carcinoma, Squamous Cell; Cell Division; Cell Line; Diglycerides; Epidermal Growth Factor; ErbB Receptors; Humans; Phorbol Esters; Phorbols; Phosphatidylinositols; Receptors, Cell Surface; Tetradecanoylphorbol Acetate | 1983 |
Epidermal growth factor and potent phorbol tumor promoters induce epidermal growth factor receptor phosphorylation in a similar but distinctively different manner in human epidermoid carcinoma A431 cells.
Topics: Carcinogens; Carcinoma, Squamous Cell; Cell Line; Epidermal Growth Factor; ErbB Receptors; Humans; Kinetics; Peptide Fragments; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Phosphorylation; Receptors, Cell Surface; Tetradecanoylphorbol Acetate | 1984 |
Phorbol esters potentiate tyrosine phosphorylation of epidermal growth factor receptors in A431 membranes by a calcium-independent mechanism.
Topics: Adenosine Triphosphate; Carcinoma, Squamous Cell; Cell Line; Cell Membrane; Epidermal Growth Factor; ErbB Receptors; Humans; Kinetics; Molecular Weight; Peptide Fragments; Phorbols; Phosphorus Radioisotopes; Phosphorylation; Receptors, Cell Surface; Tetradecanoylphorbol Acetate; Tyrosine | 1984 |
Polypeptide hormone regulation of gene transcription: specific 5' genomic sequences are required for epidermal growth factor and phorbol ester regulation of prolactin gene expression.
Topics: Base Sequence; Carcinoma, Squamous Cell; Cell Line; Clone Cells; Cloning, Molecular; DNA Restriction Enzymes; Epidermal Growth Factor; Genes; Genetic Vectors; Growth Hormone; Humans; Phorbols; Prolactin; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection | 1984 |
Tumor-promoting phorbol diesters mediate phosphorylation of the epidermal growth factor receptor.
Topics: Carcinoma, Squamous Cell; Cell Line; Cell Membrane; Epidermal Growth Factor; ErbB Receptors; Humans; Kinetics; Phorbols; Phosphorylation; Receptors, Cell Surface; Succinimides; Tetradecanoylphorbol Acetate | 1984 |
Skin painting studies in Syrian hamsters.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Cricetinae; Dose-Response Relationship, Drug; Female; Male; Melanoma; Mesocricetus; Neoplasms, Experimental; Nicotiana; Papilloma; Plants, Toxic; Sex Factors; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1983 |
Differential phosphorylation events associated with phorbol ester effects on acceleration versus inhibition of cell growth.
Topics: Animals; Blood Platelets; Carcinoma, Squamous Cell; Cell Division; Cell Line; Cells, Cultured; Humans; Leukemia, Myeloid, Acute; Lymphocytes; Mice; Mice, Inbred Strains; Molecular Weight; Phorbols; Phosphoproteins; Phosphorylation; Proteins; Skin; Tetradecanoylphorbol Acetate | 1984 |
Characteristics of neoplastic progression and tumor behavior in skin carcinogenesis by different methods: an experimental study.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cocarcinogenesis; Female; Keratoacanthoma; Mice; Neoplasms, Experimental; Papilloma; Precancerous Conditions; Sarcoma, Experimental; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1980 |
Resistance of A-431 epidermoid carcinoma cells to early membrane changes induced by tumour promoters.
Topics: Arachidonic Acid; Arachidonic Acids; Carcinogens; Carcinoma, Squamous Cell; Cells, Cultured; Choline; Drug Resistance; Humans; Membranes; Neoplasms, Experimental; Phospholipids; Tetradecanoylphorbol Acetate | 1982 |
In vitro induction of ornithine decarboxylase in urinary bladder carcinoma cells.
Topics: Animals; Carboxy-Lyases; Carcinogens; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Cell Line; Cocarcinogenesis; Enzyme Induction; Neoplasms, Experimental; Ornithine Decarboxylase; Rats; Tetradecanoylphorbol Acetate; Urinary Bladder Neoplasms; Urine | 1981 |
Cyclic AMP increases the release of parathyroid hormone-related protein from a lung-cancer cell line.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Bucladesine; Calcitonin; Carcinoma, Squamous Cell; Cell Line; Colforsin; Cyclic AMP; Humans; Kinetics; Lung Neoplasms; Neoplasm Proteins; Parathyroid Hormone-Related Protein; Protein Biosynthesis; Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Induction of 12-lipoxygenase expression by epidermal growth factor is mediated by protein kinase C in A431 cells.
Topics: Alkaloids; Arachidonate 12-Lipoxygenase; Carcinoma, Squamous Cell; Diglycerides; Enzyme Induction; Epidermal Growth Factor; Humans; Naphthalenes; Phosphatidylinositol Phosphates; Polycyclic Compounds; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Functional hyaluronan receptors are expressed on a squamous cell lung carcinoma cell line but not on other lung carcinoma cell lines.
Topics: Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Carrier Proteins; Culture Media, Conditioned; Fibroblasts; Humans; Hyaluronan Receptors; Hyaluronic Acid; Lung Neoplasms; Neoplasm Proteins; Receptors, Cell Surface; Receptors, Lymphocyte Homing; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Up-Regulation | 1995 |
Cholesterol sulfate, a second messenger for the eta isoform of protein kinase C, inhibits promotional phase in mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogens; Carcinoma, Squamous Cell; Cell Differentiation; Cell Division; Cholesterol Esters; Enzyme Activation; Enzyme Induction; Female; Hyperplasia; Isoenzymes; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; Protein Kinase C; Second Messenger Systems; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1995 |
Chemical skin carcinogenesis is prevented in mice by the induced expression of a TGF-beta related transgene.
Topics: Animals; Bone Morphogenetic Proteins; Bromodeoxyuridine; Carcinoma, Squamous Cell; Cell Division; Epidermis; Methylnitronitrosoguanidine; Mice; Mice, Transgenic; Papilloma; Proteins; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta | 1995 |
Genetic alterations cooperate with v-Ha-ras to accelerate multistage carcinogenesis in TG.AC transgenic mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Base Composition; Base Sequence; Carcinoma, Squamous Cell; Cell Division; Cell Transformation, Neoplastic; Cocarcinogenesis; Diglycerides; Female; Fibrosarcoma; Genes, p53; Genes, ras; Mice; Mice, Transgenic; Molecular Sequence Data; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1995 |
Production and secretion of platelet-derived growth factor AB by cultured human keratinocytes: regulatory effects of phorbol 12-myristate 13-acetate, etretinate, 1,25-dihydroxyvitamin D3, and several cytokines.
Topics: Carcinoma, Squamous Cell; Cells, Cultured; Culture Media; Cytokines; Dihydroxycholecalciferols; Enzyme-Linked Immunosorbent Assay; Etretinate; Fibroblasts; Humans; Keratinocytes; Platelet-Derived Growth Factor; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Wound Healing | 1995 |
Role and regulation of expression of 92-kDa type-IV collagenase (MMP-9) in 2 invasive squamous-cell-carcinoma cell lines of the oral cavity.
Topics: Amino Acid Sequence; Base Sequence; Carcinoma, Squamous Cell; Collagenases; Enzyme Induction; Gene Expression Regulation, Neoplastic; Humans; Matrix Metalloproteinase 9; Molecular Sequence Data; Molecular Weight; Mouth Neoplasms; Naphthalenes; Neoplasm Invasiveness; Neoplasm Proteins; Polycyclic Compounds; Protein Kinase C; Tetradecanoylphorbol Acetate; Tissue Inhibitor of Metalloproteinase-2; Tumor Cells, Cultured | 1993 |
Selective inhibition of the platelet-derived growth factor signal transduction pathway by a protein-tyrosine kinase inhibitor of the 2-phenylaminopyrimidine class.
Topics: 3T3 Cells; Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Division; Cell Line; Cell Line, Transformed; Epidermal Growth Factor; Female; Fibroblast Growth Factor 2; Humans; Kinetics; Mice; Mice, Inbred BALB C; Mice, Nude; Oncogene Proteins v-sis; Oncogenes; Platelet-Derived Growth Factor; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyridines; Pyrimidines; Receptors, Platelet-Derived Growth Factor; Retroviridae Proteins, Oncogenic; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection; Transplantation, Heterologous; Tumor Cells, Cultured | 1995 |
Early overexpression of cyclin D1 protein in mouse skin carcinogenesis.
Topics: Animals; Carcinoma, Squamous Cell; Cyclin D1; Cyclins; Female; Formaldehyde; Gene Expression; Hyperplasia; Immunohistochemistry; Mice; Oncogene Proteins; Papilloma; Paraffin Embedding; Precancerous Conditions; Precipitin Tests; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tissue Fixation | 1995 |
Regulation of casein kinase II by growth factors: a reevaluation.
Topics: Amino Acid Sequence; Animals; Bombesin; Carcinoma, Squamous Cell; Casein Kinase II; Cattle; Cell Line; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Induction; Epidermal Growth Factor; Fetal Blood; Fibroblast Growth Factors; Fibroblasts; Growth Substances; Humans; Insulin; Ionomycin; Lung; Molecular Sequence Data; Neoplasm Proteins; Peptide Fragments; Phosphorylation; Platelet-Derived Growth Factor; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Ribosomal Protein S6; Ribosomal Protein S6 Kinases; Ribosomal Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Lack of initiation and promotion potential of deoxynivalenol for skin tumorigenesis in Sencar mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Body Weight; Carcinoma, Squamous Cell; Data Interpretation, Statistical; Female; Hyperplasia; Mice; Organ Size; Papilloma; Random Allocation; Skin; Skin Neoplasms; Spleen; Tetradecanoylphorbol Acetate; Trichothecenes | 1995 |
Expression and function of connexin in normal and transformed human keratinocytes in culture.
Topics: Carcinoma, Squamous Cell; Cell Communication; Cell Line, Transformed; Cell Transformation, Neoplastic; Cells, Cultured; Connexins; Gap Junctions; Humans; Keratinocytes; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transfection | 1994 |
Cytogenetic analysis of malignant skin tumors induced in chemically treated TG-AC transgenic mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzene; Carcinoma, Squamous Cell; Female; Gene Expression; Genes, ras; Karyotyping; Male; Mice; Mice, Transgenic; Neoplasm Transplantation; Papilloma; Sarcoma, Experimental; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1994 |
Involvement of high-affinity binding site for EGF receptor in formation of rounding in A-431 epidermoid carcinoma cells.
Topics: Binding Sites; Carcinoma, Squamous Cell; Colforsin; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Humans; Kanamycin Kinase; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Protein Kinase C; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1994 |
Constitutive AP-1 DNA binding and transactivating ability of malignant but not benign mouse epidermal cells.
Topics: Animals; Base Sequence; Carcinoma, Squamous Cell; Chloramphenicol O-Acetyltransferase; DNA; Female; Keratinocytes; Mice; Mice, Nude; Molecular Sequence Data; Neoplasm Transplantation; Papilloma; Proto-Oncogene Proteins c-jun; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transcriptional Activation | 1994 |
Enhancement of polymorphonuclear leukocyte (PMN) function by OK-432.
Topics: Candida albicans; Carcinoma, Squamous Cell; Combined Modality Therapy; Cytokines; Cytotoxicity, Immunologic; Humans; In Vitro Techniques; Leukocytes, Mononuclear; Luminescent Measurements; Mouth Neoplasms; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitroblue Tetrazolium; Phagocytosis; Picibanil; Superoxides; Tetradecanoylphorbol Acetate | 1994 |
2-year carcinogenicity study in the male NMRI mouse with 2-ethylhexyl acrylate by epicutaneous administration.
Topics: Acrylates; Administration, Cutaneous; Air Pollutants, Occupational; Animals; Benzo(a)pyrene; Carcinogenicity Tests; Carcinogens; Carcinoma, Squamous Cell; Male; Mice; Papilloma; Skin Neoplasms; Spectrophotometry, Ultraviolet; Tetradecanoylphorbol Acetate | 1994 |
Effects of krestin (PSK) on tumorigenesis induced by two-stage and complete chemical carcinogenesis.
Topics: Adjuvants, Immunologic; Animals; Antibiotics, Antineoplastic; Benzo(a)pyrene; Carcinoma, Squamous Cell; Female; Macrophages; Mice; Mice, Inbred Strains; Neutrophils; Papilloma; Proteoglycans; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1994 |
Density-dependent induction of 92-kd type IV collagenase activity in cultures of A431 human epidermoid carcinoma cells.
Topics: Carcinoma, Squamous Cell; Cell Count; Cell Division; Collagenases; Drug Synergism; Enzyme Induction; Humans; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta; Tumor Cells, Cultured | 1994 |
Regulatory effects of 1,25-dihydroxyvitamin D3 and a novel vitamin D3 analogue MC903 on secretion of interleukin-1 alpha (IL-1 alpha) and IL-8 by normal human keratinocytes and a human squamous cell carcinoma cell line (HSC-1).
Topics: Calcitriol; Carcinoma, Squamous Cell; Cholecalciferol; Dermatologic Agents; Humans; Interleukin-1; Interleukin-8; Keratinocytes; Reference Values; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1994 |
Protection against malignant conversion of chemically induced benign skin papillomas to squamous cell carcinomas in SENCAR mice by a polyphenolic fraction isolated from green tea.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzoyl Peroxide; Carcinoma, Squamous Cell; Female; Mice; Nitroquinolines; Papilloma; Plant Extracts; Skin Neoplasms; Tea; Tetradecanoylphorbol Acetate | 1993 |
FVB/N mice: an inbred strain sensitive to the chemical induction of squamous cell carcinomas in the skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Animals; Carcinoma, Squamous Cell; Drug Resistance; Female; Genetic Predisposition to Disease; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred Strains; Papilloma; Skin Neoplasms; Species Specificity; Tetradecanoylphorbol Acetate | 1993 |
Regulation of interleukin-6 (IL-6) expression: evidence for a tissue-specific role of protein kinase C.
Topics: Alkaloids; Base Sequence; Calcimycin; Carcinoma, Squamous Cell; DNA-Binding Proteins; Gene Expression Regulation; Interleukin-1; Interleukin-6; Laryngeal Neoplasms; Lipopolysaccharides; Molecular Sequence Data; Monocytes; NF-kappa B; Organ Specificity; Polymerase Chain Reaction; Protein Kinase C; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Transcription Factors; Tumor Cells, Cultured | 1993 |
Ultraviolet radiation induces phosphorylation of the epidermal growth factor receptor.
Topics: Carcinoma, Squamous Cell; ErbB Receptors; Humans; Phosphorylation; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Ultraviolet Rays | 1994 |
Increased expression of stromelysin-3 in basal cell carcinomas.
Topics: Blotting, Northern; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Extracellular Matrix; Gene Expression; Humans; In Situ Hybridization; Matrix Metalloproteinase 11; Metalloendopeptidases; RNA, Messenger; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1994 |
Interaction of HPV-18 and nitrosomethylurea in the induction of squamous cell carcinoma.
Topics: Animals; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cocarcinogenesis; DNA, Viral; Humans; Keratinocytes; Methylnitrosourea; Mice; Mice, Inbred BALB C; Mice, Nude; Papillomaviridae; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Production of immunosuppressing melanotropins by human keratinocytes.
Topics: alpha-MSH; Carcinoma, Squamous Cell; Cell Line; Cells, Cultured; DNA Probes; Humans; Immunosuppressive Agents; Interleukin-1; Keratinocytes; Kinetics; Pro-Opiomelanocortin; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured; Ultraviolet Rays | 1993 |
Further studies on the influence of initiation dose on papilloma growth and progression during two-stage carcinogenesis in SENCAR mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anthracenes; Benzoyl Peroxide; Carcinoma, Squamous Cell; Diterpenes; Dose-Response Relationship, Drug; Female; Mice; Papilloma; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate; Time Factors | 1993 |
Inhibition of tumor formation from grafted murine papilloma cells by treatment of grafts with staurosporine, an inducer of squamous differentiation.
Topics: Alkaloids; Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Differentiation; Disease Models, Animal; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Papilloma; Protein Kinase C; Skin Neoplasms; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured | 1993 |
Overexpression of cyclin D1 in mouse skin carcinogenesis.
Topics: Animals; Base Sequence; Blotting, Northern; Carcinoma, Squamous Cell; Chromosome Mapping; Cyclin D1; Cyclins; Gene Amplification; Gene Expression; Mice; Molecular Sequence Data; Oncogene Proteins; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1993 |
Gene modulation accompanying differentiation of normal versus malignant keratinocytes.
Topics: Carcinoma, Squamous Cell; CCAAT-Enhancer-Binding Proteins; Cell Differentiation; Cornified Envelope Proline-Rich Proteins; DNA Damage; ErbB Receptors; Fibronectins; Gene Expression Regulation; Genes, fos; Genes, myc; Heat-Shock Proteins; Humans; Infant, Newborn; Interleukin-1; Keratinocytes; Kinetics; Male; Membrane Proteins; Protein Precursors; Proteins; RNA, Messenger; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Transcription Factor CHOP; Transcription Factors; Transcriptional Activation; Tumor Cells, Cultured | 1993 |
Identification and characterization of a radiation-inducible glycosylated human early-response gene.
Topics: Amino Acid Sequence; Apoptosis Regulatory Proteins; Base Sequence; Carcinoma, Squamous Cell; DNA, Complementary; Gene Expression Regulation; Genes, Immediate-Early; Glycosylation; Humans; Immediate-Early Proteins; Membrane Glycoproteins; Membrane Proteins; Molecular Sequence Data; Neoplasm Proteins; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1996 |
Localization and expression of cornifin-alpha/SPRR1 in mouse epidermis, anagen hair follicles, and skin neoplasms.
Topics: Animals; Carcinoma, Squamous Cell; Cornified Envelope Proline-Rich Proteins; Epidermis; Female; Hair Follicle; Immunohistochemistry; Membrane Proteins; Mice; Mirex; Papilloma; Proteins; RNA, Messenger; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1996 |
Autocrine regulation of membrane transforming growth factor-alpha cleavage.
Topics: Animals; Antibodies; Autoradiography; Calcimycin; Carcinoma, Squamous Cell; Cell Membrane; CHO Cells; Cricetinae; Cysteine; ErbB Receptors; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Protein Precursors; Protein Processing, Post-Translational; Rats; Recombinant Proteins; Sulfur Radioisotopes; Tetradecanoylphorbol Acetate; Transfection; Transforming Growth Factor alpha; Tumor Cells, Cultured | 1996 |
Regression and progression characteristics of papillomas induced by chrysarobin in SENCAR mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anthracenes; Benzoyl Peroxide; Carcinogens; Carcinoma, Squamous Cell; Female; Free Radicals; Mice; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1996 |
Phosphatidic acid mobilized by phospholipase D is involved in the phorbol 12-myristate 13-acetate-induced G2 delay of A431 cells.
Topics: 1-Propanol; Carcinoma, Squamous Cell; Diglycerides; Enzyme Activation; Epidermal Growth Factor; G2 Phase; Humans; Mitosis; Phosphatidic Acids; Phospholipase D; Prophase; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1996 |
Pioglitazone attenuates the inhibitory effect of phorbol ester on epidermal growth factor receptor autophosphorylation and tyrosine kinase activity.
Topics: Carcinoma, Squamous Cell; ErbB Receptors; Humans; Hypoglycemic Agents; Phosphorylation; Pioglitazone; Protein Kinase C; Protein Tyrosine Phosphatases; Receptor Protein-Tyrosine Kinases; Tetradecanoylphorbol Acetate; Thiazoles; Thiazolidinediones; Tumor Cells, Cultured | 1996 |
A hemidesmosomal transmembrane collagenous molecule, the 180-kDa bullous pemphigoid antigen (BPA II), is phosphorylated with 12-O-tetradecanoylphorbol-13-acetate in a human squamous cell carcinoma cell line (DJM-1).
Topics: Amino Acids; Animals; Antibodies, Monoclonal; Autoantigens; Autoradiography; Blotting, Western; Carcinoma, Squamous Cell; Carrier Proteins; Cattle; Cell Adhesion; Collagen; Collagen Type XVII; Cornea; Cytoskeletal Proteins; Desmosomes; Dystonin; Epithelial Cells; Epithelium; Humans; Nerve Tissue Proteins; Non-Fibrillar Collagens; Pemphigoid, Bullous; Phosphorus Radioisotopes; Phosphorylation; Precipitin Tests; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Up-regulation of vascular endothelial growth factor/vascular permeability factor in mouse skin carcinogenesis correlates with malignant progression state and activated H-ras expression levels.
Topics: Animals; Carcinoma, Squamous Cell; Cell Line, Transformed; Cell Transformation, Neoplastic; Disease Progression; Endothelial Growth Factors; Female; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Genes, ras; Interleukin 1 Receptor Antagonist Protein; Keratinocytes; Lymphokines; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred SENCAR; Neoplasm Metastasis; Neoplasm Proteins; Neovascularization, Pathologic; Oncogene Protein p21(ras); Papilloma; Precancerous Conditions; Proto-Oncogene Proteins p21(ras); RNA, Messenger; RNA, Neoplasm; Sialoglycoproteins; Skin Neoplasms; Species Specificity; Tetradecanoylphorbol Acetate; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1996 |
Retinoids suppress phorbol ester-mediated induction of cyclooxygenase-2.
Topics: Anticarcinogenic Agents; Biotransformation; Carcinoma, Squamous Cell; Cyclooxygenase 2; Dinoprostone; Diterpenes; Enzyme Induction; Gene Expression Regulation, Neoplastic; Humans; Isoenzymes; Isotretinoin; Membrane Proteins; Mouth Neoplasms; Neoplasm Proteins; Peroxidases; Prostaglandin-Endoperoxide Synthases; Retinyl Esters; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tretinoin; Tumor Cells, Cultured; Vitamin A | 1997 |
Susceptibility of 129/SvEv mice in two-stage carcinogenesis protocols to 12-O-tetradecanoylphorbol-13-acetate promotion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Cutaneous; Animals; Biomarkers; Carcinogens; Carcinoma, Squamous Cell; Cocarcinogenesis; Dermatitis, Contact; Disease Susceptibility; Dose-Response Relationship, Drug; Drug Synergism; Epidermis; Hyperplasia; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Mutant Strains; Neutrophils; Papilloma; Peroxidase; Skin Neoplasms; Species Specificity; Tetradecanoylphorbol Acetate | 1997 |
Increased expression of G1 cyclins and cyclin-dependent kinases during tumor progression of chemically induced mouse skin neoplasms.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Carcinogens; Carcinoma, Squamous Cell; Cell Cycle; Cyclin D1; Cyclin D2; Cyclin D3; Cyclin-Dependent Kinases; Cyclins; G1 Phase; Gene Expression Regulation, Neoplastic; Immunohistochemistry; Mice; Oncogene Proteins; Papilloma; S Phase; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1997 |
Chemical carcinogens and antigens contribute to cutaneous tumor promotion by depleting epidermal Langerhans cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens; Carcinogens; Carcinoma, Squamous Cell; Female; Langerhans Cells; Mice; Mice, Inbred BALB C; Papilloma; Picryl Chloride; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1997 |
Transplantation analyses of the immunogenicity of epidermal tumors generated in murine skin two-stage carcinogenesis protocols.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Division; Cocarcinogenesis; Female; Graft Rejection; Mice; Mice, Inbred SENCAR; Mice, Nude; Neoplasm Transplantation; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1997 |
Evidence that mirex promotes a unique population of epidermal cells that cannot be distinguished by their mutant Ha-ras genotype.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bromodeoxyuridine; Carcinogens; Carcinoma, Squamous Cell; Cell Division; Cells, Cultured; Cocarcinogenesis; Female; Genes, ras; Genotype; Immunohistochemistry; Keratinocytes; Mice; Mice, Inbred BALB C; Mirex; Mutation; Nitrosourea Compounds; Papilloma; S Phase; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1997 |
Lysophosphatidic acid inhibits epidermal-growth-factor-induced Stat1 signaling in human epidermoid carcinoma A431 cells.
Topics: Bradykinin; Carcinoma, Squamous Cell; DNA-Binding Proteins; Epidermal Growth Factor; Epinephrine; Genes, Reporter; GTP-Binding Proteins; Humans; Lysophospholipids; Nuclear Proteins; Oligodeoxyribonucleotides; Promoter Regions, Genetic; Protein Kinase C; Receptors, Cell Surface; Regulatory Sequences, Nucleic Acid; Signal Transduction; STAT1 Transcription Factor; Tetradecanoylphorbol Acetate; Trans-Activators; Transcription, Genetic; Tumor Cells, Cultured; Type C Phospholipases | 1997 |
Induction of 12-lipoxygenase expression by phorbol 12-myristate 13-acetate in human epidermoid carcinoma A431 cells.
Topics: Arachidonate 12-Lipoxygenase; Base Sequence; Blotting, Western; Carcinoma, Squamous Cell; DNA-Binding Proteins; Enzyme Induction; Genes, Reporter; Humans; Indoles; Luciferases; Maleimides; Microsomes; Molecular Sequence Data; Mutagenesis, Site-Directed; Nuclear Proteins; Promoter Regions, Genetic; RNA, Messenger; Sp1 Transcription Factor; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1998 |
The naturally occurring PKC inhibitor sphingosine and tumor promoter phorbol ester potentially induce tyrosine phosphorylation/activation of oncogenic proline-directed protein kinase FA/GSK-3alpha in a common signalling pathway.
Topics: Antineoplastic Agents; Calcium-Calmodulin-Dependent Protein Kinases; Carcinogens; Carcinoma, Squamous Cell; Enzyme Activation; Enzyme Induction; Genistein; Glycogen Synthase Kinase 3; Humans; Phosphorylation; Phosphotyrosine; Protein Kinase C; Signal Transduction; Sphingosine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine | 1998 |
The expression of desmoglein isoforms in cultured human keratinocytes is regulated by calcium, serum, and protein kinase C.
Topics: Blood; Bryostatins; Calcium; Carcinoma, Squamous Cell; Cell Adhesion Molecules; Cell Differentiation; Cell Line, Transformed; Cells, Cultured; Culture Media; Cytoskeletal Proteins; Desmoglein 1; Desmoglein 2; Desmogleins; Desmoplakins; Desmosomes; Enzyme Activation; Gene Expression Regulation; Humans; Infant, Newborn; Keratinocytes; Kinetics; Lactones; Macrolides; Male; Protein Kinase C; Skin; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1998 |
Inhibition of the p38 mitogen-activated protein kinase by SB 203580 blocks PMA-induced Mr 92,000 type IV collagenase secretion and in vitro invasion.
Topics: Calcium-Calmodulin-Dependent Protein Kinases; Carcinoma, Squamous Cell; Collagenases; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Head and Neck Neoplasms; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 1; Matrix Metalloproteinase 9; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase 9; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Neoplasm Invasiveness; p38 Mitogen-Activated Protein Kinases; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Pyridines; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1998 |
Induction of 12-lipoxygenase expression by epidermal growth factor is mediated by protein kinase C in A431 cells.
Topics: Arachidonate 12-Lipoxygenase; Arachidonic Acid; Carcinoma, Squamous Cell; Enzyme Induction; Enzyme Inhibitors; Epidermal Growth Factor; Humans; Hydroquinones; Isoenzymes; Microsomes; Protein Kinase C; Protein-Tyrosine Kinases; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1997 |
E2F1 messenger RNA is destabilized in response to a growth inhibitor in normal human keratinocytes but not in a squamous carcinoma cell line.
Topics: Blotting, Northern; Carcinoma, Squamous Cell; Carrier Proteins; Cell Cycle Proteins; Cells, Cultured; Cycloheximide; Dactinomycin; DNA; DNA-Binding Proteins; Down-Regulation; E2F Transcription Factors; E2F1 Transcription Factor; Humans; Keratinocytes; Retinoblastoma-Binding Protein 1; RNA Processing, Post-Transcriptional; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Transcription Factor DP1; Transcription Factors | 1998 |
Staurosporine-induced versus spontaneous squamous metaplasia in pre- and postmenopausal breast tissue.
Topics: Adult; Aged; Anticarcinogenic Agents; Breast; Breast Neoplasms; Carcinogens; Carcinoma, Squamous Cell; Cell Differentiation; Cell Division; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Humans; Immunophenotyping; Keratin-10; Keratinocytes; Keratins; Middle Aged; Naphthalenes; Postmenopause; Premenopause; Protein Kinase C; Staurosporine; Tamoxifen; Tetradecanoylphorbol Acetate; Thrombomodulin; Tumor Cells, Cultured; Up-Regulation | 1998 |
Immunomodulatory effects of tretinoin in combination with clindamycin.
Topics: Acne Vulgaris; Adjuvants, Immunologic; Anti-Bacterial Agents; Anti-Inflammatory Agents; Carcinogens; Carcinoma, Squamous Cell; Clindamycin; Humans; Interferon-gamma; Interleukin-5; Interleukin-6; Keratinocytes; Keratolytic Agents; Lymphocytes; Monocytes; Superantigens; Tetradecanoylphorbol Acetate; Th1 Cells; Th2 Cells; Tretinoin | 1998 |
Genetic deletion of p21WAF1 enhances papilloma formation but not malignant conversion in experimental mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Differentiation; Biomarkers; Carcinogens; Carcinoma, Squamous Cell; Cell Division; Cocarcinogenesis; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Disease Progression; Epidermis; Gene Deletion; Genes, p53; Genotype; Hyperplasia; Mice; Mice, Knockout; Mitotic Index; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53 | 1999 |
Altered expression of interleukin-1 receptor antagonist in different stages of mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anthralin; Blotting, Northern; Blotting, Western; Carcinogens; Carcinoma, Squamous Cell; Cell Polarity; Cytoplasm; Disease Progression; Epidermis; Gene Expression Regulation, Neoplastic; Hyperplasia; Inflammation; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Keratinocytes; Mice; Mice, Inbred SENCAR; Neoplasm Proteins; Papilloma; Precancerous Conditions; RNA, Messenger; RNA, Neoplasm; Sialoglycoproteins; Skin Diseases; Skin Neoplasms; Tetradecanoylphorbol Acetate; Thapsigargin; Tumor Cells, Cultured | 1999 |
Inhibitory effects of caffeic acid phenethyl ester on the activity and expression of cyclooxygenase-2 in human oral epithelial cells and in a rat model of inflammation.
Topics: Air; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Arachidonic Acids; Caffeic Acids; Calcimycin; Carcinoma, Squamous Cell; Carrageenan; Cell Membrane; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Enzyme Activation; Enzyme Induction; Epithelial Cells; Genetic Vectors; Humans; Indomethacin; Inflammation; Ionophores; Isoenzymes; Male; Membrane Lipids; Membrane Proteins; Mouth Mucosa; Nucleopolyhedroviruses; Phenylethyl Alcohol; Phospholipids; Promoter Regions, Genetic; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred Lew; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1999 |
A multihit, multistage model of chemical carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cocarcinogenesis; DNA Mutational Analysis; DNA, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Genes, ras; Keratinocytes; Keratins; Mice; Models, Biological; Neoplasm Proteins; Papilloma; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; S Phase; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1999 |
Migratory phenotypes of HSC-3 squamous carcinoma cell line induced by EGF and PMA: relevance to migration of loosening of adhesion and vinculin-associated focal contacts with prominent filopodia.
Topics: Carcinogens; Carcinoma, Squamous Cell; Cell Adhesion; Cell Movement; Epidermal Growth Factor; Fibronectins; Humans; Intercellular Junctions; Pseudopodia; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vinculin | 1999 |
Cytokine biosynthesis by tumor-infiltrating T lymphocytes from human non-small-cell lung carcinoma.
Topics: Adenocarcinoma; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; CD3 Complex; Cytokines; Gene Expression Regulation; Humans; Interleukin-2; Ionomycin; Lung Neoplasms; Lymphocyte Activation; Lymphocytes, Tumor-Infiltrating; Muromonab-CD3; T-Lymphocytes; Tetradecanoylphorbol Acetate | 2000 |
Development and initial characterization of several new inbred strains of SENCAR mice for studies of multistage skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Dose-Response Relationship, Drug; Mice; Mice, Inbred SENCAR; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2000 |
Ursolic acid inhibits cyclooxygenase-2 transcription in human mammary epithelial cells.
Topics: Blotting, Northern; Breast; Carcinoma, Squamous Cell; Cell Line; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Epithelial Cells; Female; Humans; Isoenzymes; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; Membrane Proteins; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Plasmids; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; RNA, Ribosomal, 18S; Signal Transduction; Tetradecanoylphorbol Acetate; Tongue Neoplasms; Transcription, Genetic; Transfection; Triterpenes; Tumor Cells, Cultured; Ursolic Acid | 2000 |
Allelotype analysis of chemically induced squamous cell carcinomas in F(1) hybrids of two inbred mouse strains with different susceptibility to tumor progression.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alleles; Animals; Carcinogens; Carcinoma, Squamous Cell; Chimera; Crosses, Genetic; Disease Progression; Genetic Predisposition to Disease; Genotype; Humans; Loss of Heterozygosity; Mice; Mice, Inbred SENCAR; Microsatellite Repeats; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2000 |
Aberrant cell cycle progression contributes to the early-stage accelerated carcinogenesis in transgenic epidermis expressing the dominant negative TGFbetaRII.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bromodeoxyuridine; Carcinogens; Carcinoma, Squamous Cell; Carrier Proteins; Cell Cycle; Cell Cycle Proteins; Cell Transformation, Neoplastic; Centrosome; Cyclin-Dependent Kinase Inhibitor p15; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p27; Epidermal Cells; Gene Expression; Mice; Mice, Transgenic; Microtubule-Associated Proteins; Mitosis; Papilloma; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; Tetradecanoylphorbol Acetate; Time Factors; Tumor Suppressor Proteins | 2000 |
Targeted disruption of the epidermal growth factor receptor inhibits development of papillomas and carcinomas from human papillomavirus-immortalized keratinocytes.
Topics: Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Line, Transformed; Cell Transformation, Viral; Cocarcinogenesis; Disease Progression; ErbB Receptors; Gene Expression; Genes, ras; Genotype; Humans; Keratinocytes; Mice; Mice, Inbred BALB C; Mice, Nude; Mutation; Oncogene Proteins, Viral; Papilloma; Papillomaviridae; Papillomavirus E7 Proteins; Repressor Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2000 |
Constitutive expression of erbB2 in epidermis of transgenic mice results in epidermal hyperproliferation and spontaneous skin tumor development.
Topics: Animals; Carcinogens; Carcinoma, Squamous Cell; Cattle; Cell Differentiation; Cell Division; Cell Transformation, Neoplastic; Cocarcinogenesis; Dimerization; Disease Progression; Epidermis; ErbB Receptors; Female; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Genes, erbB-2; Genes, ras; Genes, Synthetic; Hyperplasia; Keratins; Male; Mice; Mice, Inbred ICR; Mice, Transgenic; Neoplasm Proteins; Papilloma; Phosphorylation; Promoter Regions, Genetic; Protein Processing, Post-Translational; Rats; Receptor, ErbB-2; Receptor, ErbB-3; Recombinant Fusion Proteins; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transgenes | 2000 |
Protein kinase C-epsilon transgenic mice: a unique model for metastatic squamous cell carcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Disease Models, Animal; Disease Progression; Female; Hair Follicle; Isoenzymes; Lymphatic Metastasis; Male; Mice; Mice, Transgenic; Protein Kinase C; Protein Kinase C-epsilon; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2001 |
Analysis of c-Ha-ras gene mutations in skin tumors induced in carcinogenesis-susceptible and carcinogenesis-resistant mice by different two-stage protocols or tumor promoter alone.
Topics: Animals; Benz(a)Anthracenes; Benzoyl Peroxide; Carcinogens; Carcinoma, Squamous Cell; DNA Primers; Drug Resistance, Neoplasm; Genes, ras; Genetic Predisposition to Disease; Mice; Mice, Inbred Strains; Mutation; Papilloma; Polymerase Chain Reaction; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2001 |
[p53 gene mutations in mouse skin tumors induced by DMBA-TPA-MNNG].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Exons; Genes, p53; Methylnitronitrosoguanidine; Mice; Mice, Inbred SENCAR; Papilloma; Point Mutation; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1998 |
Targeted expression of bcl-2 to murine basal epidermal keratinocytes results in paradoxical retardation of ultraviolet- and chemical-induced tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Female; Genes, ras; Humans; Keratinocytes; Mice; Mice, Transgenic; Mutagenesis; Papilloma; Proto-Oncogene Proteins c-bcl-2; Skin Neoplasms; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 2001 |
Suppression of skin tumorigenesis in c-Jun NH(2)-terminal kinase-2-deficient mice.
Topics: Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; DNA; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinase 9; Mitogen-Activated Protein Kinases; Papilloma; Phosphorylation; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factor AP-1 | 2001 |
Influence of beta1 integrins on epidermal squamous cell carcinoma formation in a transgenic mouse model: alpha3beta1, but not alpha2beta1, suppresses malignant conversion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, CD; Antigens, Neoplasm; Basigin; Carcinogens; Carcinoma, Squamous Cell; Cell Division; Cell Transformation, Neoplastic; Female; Integrin alpha3beta1; Integrins; Keratinocytes; Membrane Glycoproteins; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Transgenic; Papilloma; Receptors, Collagen; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tetraspanin 28 | 2001 |
Membrane type I-matrix metalloproteinase-mediated degradation of type I collagen by oral squamous cell carcinoma cells.
Topics: Animals; Blotting, Western; Carcinoma, Squamous Cell; Cell Membrane; Collagen; Collagenases; Enzyme Activation; Humans; Matrix Metalloproteinase 1; Matrix Metalloproteinase 13; Matrix Metalloproteinase 2; Matrix Metalloproteinases, Membrane-Associated; Metalloendopeptidases; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate; Tongue Neoplasms; Tumor Cells, Cultured | 2001 |
Identification of specific gravity sensitive signal transduction pathways in human A431 carcinoma cells.
Topics: Calcimycin; Carcinogens; Carcinoma, Squamous Cell; Colforsin; Epidermal Growth Factor; Gene Expression Regulation, Neoplastic; Gravitation; Humans; Ionophores; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rotation; Signal Transduction; Space Flight; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Weightlessness; Weightlessness Simulation | 1992 |
Lack of promotion of 7,12-dimethylbenz[a]anthracene-initiated mouse skin carcinogenesis by 1.5 GHz electromagnetic near fields.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenocorticotropic Hormone; Animals; Carcinogens; Carcinoma, Squamous Cell; Corticosterone; Electromagnetic Fields; Epidermis; Female; Incidence; Melatonin; Mice; Mice, Inbred ICR; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2001 |
Expression and regulation of MMP-20 in human tongue carcinoma cells.
Topics: Amelogenin; Carcinogens; Carcinoma, Squamous Cell; Caseins; Cell Adhesion Molecules; Cell Line; Collagen Type I; Collagen Type II; Collagen Type IV; Dental Enamel Proteins; Enzyme Precursors; Fibronectins; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Kalinin; Laminin; Matrix Metalloproteinase 20; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Recombinant Proteins; RNA, Messenger; Tenascin; Tetradecanoylphorbol Acetate; Tongue Neoplasms; Transforming Growth Factor beta; Trypsin; Tumor Cells, Cultured; Up-Regulation | 2001 |
Effects of platelet activating factor, butyrate and interleukin-6 on cyclooxygenase-2 expression in human esophageal cancer cells.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Butyrates; Carcinoma, Squamous Cell; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Esophageal Neoplasms; Female; Humans; Immunohistochemistry; Interleukin-6; Isoenzymes; Male; Membrane Proteins; Middle Aged; Platelet Activating Factor; Platelet Membrane Glycoproteins; Prostaglandin-Endoperoxide Synthases; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Reverse Transcriptase Polymerase Chain Reaction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2002 |
Expression and regulation of collagenase-2 (MMP-8) in head and neck squamous cell carcinomas.
Topics: Blotting, Southern; Blotting, Western; Carcinoma, Squamous Cell; Female; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Humans; In Situ Hybridization; Male; Matrix Metalloproteinase 8; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tumor Cells, Cultured | 2002 |
Calgranulins S100A8 and S100A9 are negatively regulated by glucocorticoids in a c-Fos-dependent manner and overexpressed throughout skin carcinogenesis.
Topics: Animals; Anti-Inflammatory Agents; Antigens, Differentiation; Antineoplastic Agents, Hormonal; Calcium; Calcium-Binding Proteins; Calgranulin A; Calgranulin B; Carcinogens; Carcinoma, Squamous Cell; Dexamethasone; Disease Progression; Drug Eruptions; Female; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Genes, fos; Keratinocytes; Leukocytes; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Knockout; Papilloma; Protein Kinase C; Proto-Oncogene Proteins c-fos; S100 Proteins; Skin Neoplasms; Specific Pathogen-Free Organisms; Tetradecanoylphorbol Acetate; Transcription Factor AP-1 | 2002 |
The carcinogenic effect of TPA (12-0-tetradecanoylphorbol-13-acetate) when applied to the skin of hairless mice.
Topics: Animals; Carcinoma, Squamous Cell; Fibrosarcoma; Mice; Mice, Nude; Papilloma; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1979 |
Effects of structural changes on the tumor-promoting activity of phorbol myristate acetate on mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aldehydes; Animals; Carcinoma, Squamous Cell; Decanoates; Drug Synergism; Mice; Mice, Inbred ICR; Neoplasms, Experimental; Papilloma; Phorbols; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1979 |
Life history and histopathology of ultraviolet light-induced skin tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cocarcinogenesis; Cricetinae; Female; Mice; Neoplasms, Experimental; Neoplasms, Radiation-Induced; Papilloma; Rats; Sarcoma, Experimental; Skin Neoplasms; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 1978 |
Photosensitized reactions and carcinogenesis.
Topics: Animals; Carcinoma, Squamous Cell; Cocarcinogenesis; DNA; Female; Methoxsalen; Mice; Mice, Nude; Neoplasms, Experimental; Neoplasms, Radiation-Induced; Photochemotherapy; Skin Neoplasms; Species Specificity; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 1978 |
Inhibition of two-stage carcinogenesis in mouse skin with bis(2-chloroethyl)sulfide.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Carcinoma, Squamous Cell; Female; Mice; Mice, Inbred ICR; Mustard Compounds; Neoplasms, Experimental; Papilloma; Phorbols; Skin Neoplasms; Sulfides; Tetradecanoylphorbol Acetate | 1976 |
Transmaternal variation of the Berenblum experiment with NMRI-mice: tumour initiation with DMBA via mothers milk followed by promotion with the phorbol ester TPA.
Topics: Animals; Animals, Newborn; Benz(a)Anthracenes; Carcinoma, Squamous Cell; Female; Mice; Milk; Neoplasms, Experimental; Papilloma; Tetradecanoylphorbol Acetate | 1976 |
Tumour-initiating activities on mouse skin of dihydrodiols derived from benzo[a]pyrene.
Topics: Animals; Benzopyrenes; Carcinoma, Squamous Cell; Female; Fibrosarcoma; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1976 |
Selective promoting activity of phorbol myristate acetate in experimental skin carcinogenesis.
Topics: Animals; Carcinoma, Squamous Cell; Female; Fibrosarcoma; Male; Methylcholanthrene; Mice; Neoplasms, Experimental; Phorbols; Precancerous Conditions; Rhabdomyosarcoma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1976 |
Three types of human lung tumour cell lines can be distinguished according to surface expression of endogenous urokinase and their capacity to bind exogenous urokinase.
Topics: Adenocarcinoma; Antibodies, Monoclonal; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cell Line; Cell Membrane; Humans; Immunochemistry; Kinetics; Lung Neoplasms; Mesothelioma; Protein Binding; Tetradecanoylphorbol Acetate; Urokinase-Type Plasminogen Activator | 1992 |
The effects of interferon-beta on phorbol ester or calcium ionophore-induced intercellular adhesion molecule-I expression in epidermal carcinoma cells.
Topics: Calcimycin; Carcinoma, Squamous Cell; Cell Adhesion Molecules; Cell Line; Enzyme Activation; Humans; In Vitro Techniques; Intercellular Adhesion Molecule-1; Interferon-beta; Keratinocytes; Protein Kinase C; Second Messenger Systems; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1992 |
Development of an in vitro model to study carcinogen-induced neoplastic progression of initiated mouse epidermal cells.
Topics: Animals; Animals, Newborn; Base Sequence; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cells, Cultured; Epidermal Cells; Epidermis; Genes, ras; Keratinocytes; Keratins; Methylnitronitrosoguanidine; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Oligodeoxyribonucleotides; Papilloma; Polymerase Chain Reaction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transfection | 1992 |
Dissociation of sensitivities to tumor promotion and progression in outbred and inbred SENCAR mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzoyl Peroxide; Carcinoma, Squamous Cell; Female; Genes, ras; Keratins; Methylnitronitrosoguanidine; Mice; Mutation; Papilloma; Skin Neoplasms; Species Specificity; Tetradecanoylphorbol Acetate | 1992 |
12-O-tetradecanoylphorbol 13-acetate induced differentiation in human lung squamous carcinoma cells.
Topics: Antigens, Neoplasm; Carcinoma, Squamous Cell; Cell Differentiation; Cell Division; Humans; Keratins; Lung Neoplasms; Protein Precursors; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
Aberrant expression of the simple epithelial type II keratin 8 by mouse skin carcinomas but not papillomas.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Blotting, Northern; Carcinoma, Squamous Cell; Electrophoresis, Polyacrylamide Gel; Epithelium; Female; Fluorescent Antibody Technique; Gene Expression; Genes, ras; Immunoenzyme Techniques; Keratins; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mutation; Papilloma; RNA; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1992 |
In vitro secretion of transforming growth factor alpha (TGF-alpha): a comparison of the A431 cell line with three human oesophageal squamous cell carcinoma lines.
Topics: Carcinoma, Squamous Cell; Epidermal Growth Factor; ErbB Receptors; Esophageal Neoplasms; Humans; In Vitro Techniques; Secretory Rate; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha; Tumor Cells, Cultured | 1992 |
Phorbol ester- and calcium-induced reorganization of 180-kDa bullous pemphigoid antigen on the ventral surface of cultured human keratinocytes as studied by immunofluorescence and immunoelectron microscopy.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Autoantigens; Calcium; Carcinoma, Squamous Cell; Carrier Proteins; Cell Membrane; Cells, Cultured; Collagen; Collagen Type XVII; Cytoskeletal Proteins; Desmosomes; Dystonin; Fluorescent Antibody Technique; Humans; Isoquinolines; Keratinocytes; Microscopy, Immunoelectron; Molecular Weight; Nerve Tissue Proteins; Non-Fibrillar Collagens; Pemphigoid, Bullous; Piperazines; Protein Kinase C; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
Growth control by epidermal growth factor and transforming growth factor-alpha in human lung squamous carcinoma cells.
Topics: Carcinoma, Squamous Cell; Cell Cycle; Cell Division; Cell Line; Culture Media; Epidermal Growth Factor; ErbB Receptors; Humans; Immunohistochemistry; Lung Neoplasms; Protein Precursors; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha | 1992 |
Effects of epidermal growth factor on glycolysis in A431 cells.
Topics: Calcium; Carcinoma, Squamous Cell; Cell Line; Epidermal Growth Factor; Fructosediphosphates; Glycolysis; Humans; Phosphofructokinase-1; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
The respiratory burst of neutrophils, a prognostic parameter in head and neck cancer?
Topics: Carcinoma, Squamous Cell; Combined Modality Therapy; Head and Neck Neoplasms; Humans; Middle Aged; Neutrophils; Prognosis; Respiratory Burst; Survival Analysis; Tetradecanoylphorbol Acetate | 1992 |
[The role of signal transduction systems in the regulation of production and secretion of TA-4 by cultured cervical epidermoid carcinoma cells (CaSki)].
Topics: Antigens, Neoplasm; Calcimycin; Carcinoma, Squamous Cell; Cholera Toxin; Female; Humans; Serpins; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Uterine Cervical Neoplasms | 1992 |
Metastatic potential of mouse skin carcinomas produced by different protocols of chemical carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; DNA, Neoplasm; Female; gamma-Glutamyltransferase; Lung Neoplasms; Methylnitronitrosoguanidine; Mice; Neoplasm Metastasis; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1991 |
cAMP-mediated modulation of signal transduction of epidermal growth factor (EGF) receptor systems in human epidermoid carcinoma A431 cells. Depression of EGF-dependent diacylglycerol production and EGF receptor phosphorylation.
Topics: 1-Methyl-3-isobutylxanthine; Alprostadil; Carcinoma, Squamous Cell; Cell Line; Cell Membrane; Cholera Toxin; Colforsin; Cyclic AMP; Diglycerides; Epidermal Growth Factor; ErbB Receptors; Glycerides; Humans; Kinetics; Peptide Mapping; Phosphopeptides; Phosphorylation; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Tissue-specific expression of murine keratin K13 in internal stratified squamous epithelia and its aberrant expression during two-stage mouse skin carcinogenesis is associated with the methylation state of a distinct CpG site in the remote 5'-flanking reg
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Base Sequence; Carcinoma, Squamous Cell; Deoxyribonuclease I; DNA, Neoplasm; Epithelial Cells; Epithelium; Female; Gene Expression Regulation, Neoplastic; Immunohistochemistry; Keratins; Methylation; Mice; Molecular Sequence Data; Nucleotides; Organ Specificity; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Identification of a cloned sequence activated during multi-stage carcinogenesis in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Base Sequence; Carcinoma, Squamous Cell; Gene Expression Regulation, Neoplastic; Keratins; Mice; Molecular Sequence Data; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1991 |
Assessment of the antioxidant/prooxidant status of murine skin following topical treatment with 12-O-tetradecanoylphorbol-13-acetate and throughout the ontogeny of skin cancer. Part I: Quantitation of superoxide dismutase, catalase, glutathione peroxidase
Topics: Administration, Topical; Animals; Carcinoma, Squamous Cell; Catalase; Female; Glutathione Peroxidase; Mice; Mice, Inbred Strains; Oxygen; Papilloma; Phenotype; Skin; Skin Neoplasms; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Xanthine Dehydrogenase; Xanthine Oxidase | 1991 |
Assessment of the antioxidant/prooxidant status of murine skin following topical treatment with 12-O-tetradecanoylphorbol-13-acetate and throughout the ontogeny of skin cancer. Part II: Quantitation of glutathione and glutathione disulfide.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Administration, Topical; Aging; Animals; Carcinoma, Squamous Cell; Epidermis; Female; Glutathione; Glutathione Disulfide; Mice; Oxidation-Reduction; Oxygen; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1991 |
Inhibitory regulation of serum factor(s)-caused ornithine decarboxylase induction by the protein kinase C system in A431 human epidermoid carcinoma cells.
Topics: Blood; Carcinoma, Squamous Cell; Down-Regulation; Enzyme Activation; Enzyme Induction; Humans; In Vitro Techniques; Ornithine Decarboxylase; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
Activation of the rasHa gene in urethane-initiated papillomas induced by protocols with high and low frequencies of malignant conversion.
Topics: 3T3 Cells; Animals; Blotting, Southern; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; DNA, Neoplasm; Drug Interactions; Female; Gene Expression Regulation, Neoplastic; Genes, ras; Male; Mice; Mice, Nude; Neoplasm Transplantation; Papilloma; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured; Urethane | 1991 |
Multiple signal transduction pathways lead to extracellular ATP-stimulated mitogenesis in mammalian cells: I. Involvement of protein kinase C-dependent and -independent pathways.
Topics: Adenosine Triphosphate; Animals; Bombesin; Carcinoma, Squamous Cell; Cell Line; Diglycerides; DNA; Down-Regulation; Drug Synergism; Enzyme Activation; Fibroblasts; Glycerides; Humans; Mice; Mitosis; Pertussis Toxin; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphatidylcholines; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Vasopressins; Virulence Factors, Bordetella | 1991 |
A comparative study on the effect of tumor promoters on poly ADP-ribosylation in A431 cells.
Topics: Benzamides; Calcium; Carcinogens; Carcinoma, Squamous Cell; DNA; Gene Expression Regulation, Enzymologic; Humans; In Vitro Techniques; NAD; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Tetradecanoylphorbol Acetate | 1990 |
Effect of tumour promoters on poly ADP-ribosylation in human epidermoid carcinoma HeP2 cells.
Topics: Benzoyl Peroxide; Carcinogens; Carcinoma, Squamous Cell; Diterpenes; Enzyme Activation; Humans; NAD; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Terpenes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Signal transduction by the epidermal growth factor receptor after functional desensitization of the receptor tyrosine protein kinase activity.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Carcinoma, Squamous Cell; Cell Line; Epidermal Growth Factor; ErbB Receptors; Humans; Inositol Phosphates; Kinetics; Molecular Sequence Data; Oligopeptides; Peptide Fragments; Phosphorylation; Protein-Tyrosine Kinases; Signal Transduction; Substrate Specificity; Tetradecanoylphorbol Acetate | 1990 |
Reduced tyrosine phosphorylation and nonresponsiveness to EGF-mediated cytotoxicity in EGF receptor-hyperproducing UCVA-1 cells.
Topics: Carcinoma, Squamous Cell; Cell Division; Down-Regulation; Epidermal Growth Factor; ErbB Receptors; Humans; Pancreatic Neoplasms; Peptide Mapping; Phosphatidylinositols; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine | 1990 |
Herpes simplex virus type-1 immediate-early gene expression and shut off of host protein synthesis are inhibited in neomycin-treated human epidermoid carcinoma 2 cells.
Topics: Animals; Blotting, Northern; Carcinoma, Squamous Cell; DNA, Viral; Dose-Response Relationship, Drug; Gene Expression Regulation, Viral; Humans; In Vitro Techniques; Neomycin; Phosphatidylinositols; RNA, Messenger; RNA, Viral; Simplexvirus; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vero Cells; Viral Proteins; Virus Replication | 1990 |
Herpes simplex virus type-1-induced stimulation of ribosomal protein S6 phosphorylation is inhibited in neomycin-treated human epidermoid carcinoma 2 cells and in ras-transformed cells.
Topics: Animals; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Genes, ras; Herpes Simplex; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Neomycin; Phosphatidylinositols; Phosphorylation; Protein Kinase C; Rats; Ribosomal Protein S6; Ribosomal Proteins; Simplexvirus; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Biphasic effects of 12-O-tetradecanoylphorbol-13-acetate on the cell morphology of low calcium-grown human epidermal carcinoma cells: involvement of translocation and down regulation of protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Calcium; Calcium Channel Blockers; Carcinoma, Squamous Cell; Cell Division; Cell Line; Culture Media; Humans; Isoquinolines; Keratins; Piperazines; Protein Kinase C; Tetradecanoylphorbol Acetate | 1988 |
Suppression of keratinocyte differentiation in SSC-9 human squamous carcinoma cells by benzo[a]pyrene, 12-O-tetradecanoylphorbol-13-acetate and hydroxyurea.
Topics: Benzo(a)pyrene; Carcinoma, Squamous Cell; Cell Differentiation; Cell Line; Enzyme Induction; Epidermal Cells; Epidermis; Humans; Hydroxyurea; Keratins; Kinetics; Protein Precursors; Tetradecanoylphorbol Acetate; Transglutaminases | 1988 |
Correlation between cell-cell contact formation and activation of protein kinase C in a human squamous cell carcinoma cell line.
Topics: Calcium; Carcinoma, Squamous Cell; Cell Communication; Enzyme Activation; Humans; Intermediate Filaments; Keratins; Osmolar Concentration; Protein Kinase C; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
Further characterization of skin tumor promotion and progression by mezerein in SENCAR mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Diterpenes; DNA; Female; Mice; Papilloma; Skin; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate | 1989 |
Effects of oral versus topical administration of cyclosporine on phorbol ester promotion of murine epidermal carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Administration, Topical; Animals; Carcinoma, Squamous Cell; Cyclosporins; Hyperplasia; Male; Mice; Neutrophils; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1989 |
Regulation of ornithine decarboxylase in normal and neoplastic mouse and human epidermis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Chromatography, Gel; Epidermis; Female; Humans; Kinetics; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1989 |
Tumor initiation in mouse skin by cutting oils.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Female; Hyperplasia; Industrial Oils; Mice; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1989 |
Involvement of protein kinase C in translocation of desmoplakins from cytosol to plasma membrane during desmosome formation in human squamous cell carcinoma cells grown in low to normal calcium concentration.
Topics: Calcimycin; Calcium; Carcinoma, Squamous Cell; Cell Membrane; Cytoskeletal Proteins; Cytosol; Desmoplakins; Desmosomes; Diglycerides; Dose-Response Relationship, Drug; Humans; Phorbol 12,13-Dibutyrate; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
Tumor associated proteins of rat skin tumor induced by 7,12-dimethylbenz[a]anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Surface; Carcinoma, Squamous Cell; Cell Membrane; Glycoproteins; Membrane Proteins; Papilloma; Rats; Rats, Inbred Strains; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1989 |
Lack of phosphorylation of lipocortin I in A431 epidermoid carcinoma cells treated with phorbol esters.
Topics: Annexins; Antibody Specificity; Carcinoma, Squamous Cell; Cell Line; Cross Reactions; Glycoproteins; Humans; Immune Sera; Phosphorylation; Precipitin Tests; Protein Kinase C; Substrate Specificity; Tetradecanoylphorbol Acetate | 1989 |
Proliferating, transformed keratinocytes cultured under low Ca2+ conditions exhibit high-affinity epidermal growth factor receptors.
Topics: Antibodies, Monoclonal; Calcium; Carcinoma, Squamous Cell; Cell Division; Cell Transformation, Viral; Cells, Cultured; Epidermal Growth Factor; ErbB Receptors; Humans; Keratinocytes; Simian virus 40; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
Activation of the cellular Harvey ras gene in mouse skin tumors initiated with urethane.
Topics: Animals; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cocarcinogenesis; Codon; DNA Probes; Gene Amplification; Genes, ras; Mice; Mutation; Papilloma; Polymorphism, Restriction Fragment Length; Proto-Oncogene Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Stem Cell Assay; Urethane | 1989 |
Detection of distinct transforming genes in X-ray induced tumors.
Topics: Animals; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cells, Cultured; Cocarcinogenesis; Mice; Mice, Inbred Strains; Neoplasms, Radiation-Induced; Oncogenes; Papilloma; Restriction Mapping; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transfection; X-Rays | 1989 |
Receptor specific for certain nucleotides stimulates inositol phosphate metabolism and Ca2+ fluxes in A431 cells.
Topics: Adenosine Triphosphate; Calcium; Carcinoma, Squamous Cell; Chlortetracycline; Cytoskeletal Proteins; Down-Regulation; Epidermal Growth Factor; Fluorescence; Humans; Inositol Phosphates; Nucleotides; Phosphorylation; Protein-Tyrosine Kinases; Receptors, Purinergic; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Uridine Triphosphate | 1989 |
Experimental analysis of the effects of cyclosporine on the induction and growth of epithelial tumors.
Topics: Adenoma; Administration, Oral; Administration, Topical; Animals; Carcinoma, Squamous Cell; Cell Division; Cyclosporins; Lung Neoplasms; Male; Mice; Skin Neoplasms; Tetradecanoylphorbol Acetate; Urethane | 1989 |
Protein kinase C inhibition of the epidermal growth factor receptor tyrosine protein kinase activity is independent of the oligomeric state of the receptor.
Topics: Carcinoma, Squamous Cell; Cell Line; Epidermal Growth Factor; ErbB Receptors; Humans; Kinetics; Macromolecular Substances; Molecular Weight; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Tetradecanoylphorbol Acetate | 1989 |
Induction and suppression of type I collagenase in cultured human cells.
Topics: Carcinoma, Squamous Cell; Cell Line; Concanavalin A; Dexamethasone; Epidermal Growth Factor; Fibroblast Growth Factors; Fibroblasts; Growth Substances; Humans; Microbial Collagenase; Molecular Weight; Ocular Physiological Phenomena; Tetradecanoylphorbol Acetate | 1987 |
Analysis of the rasH oncogene and its p21 product in chemically induced skin tumors and tumor-derived cell lines.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cell Line; Deoxyribonucleases, Type II Site-Specific; DNA Restriction Enzymes; DNA, Neoplasm; Female; Mice; Oncogenes; Papilloma; Polymorphism, Genetic; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); Skin Neoplasms; Tetradecanoylphorbol Acetate; Transfection | 1987 |
Phorbol esters induce transient internalization without degradation of unoccupied epidermal growth factor receptors.
Topics: Carcinoma, Squamous Cell; Cell Line; Cell Membrane; Endosomes; Epidermal Growth Factor; ErbB Receptors; Golgi Apparatus; Histocytochemistry; Humans; Lysosomes; Phorbols; Protein Kinase C; Protein Kinases; Receptors, Cell Surface; Tetradecanoylphorbol Acetate | 1985 |
Sequential study of gamma-glutamyltransferase during complete and two-stage mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cell Differentiation; Female; gamma-Glutamyltransferase; Mice; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1986 |
2,3,7,8-Tetrachlorodibenzo-p-dioxin and polycyclic aromatic hydrocarbons suppress retinoid-induced tissue transglutaminase in SCC-4 cultured human squamous carcinoma cells.
Topics: Carcinoma, Squamous Cell; Cell Line; Dioxins; Diterpenes; Enzyme Induction; Humans; Kinetics; Polychlorinated Dibenzodioxins; Polycyclic Compounds; Retinyl Esters; Tetradecanoylphorbol Acetate; Transglutaminases; Tretinoin; Vitamin A | 1988 |
sn-1,2-Dioctanoylglycerol. A cell-permeable diacylglycerol that mimics phorbol diester action on the epidermal growth factor receptor and mitogenesis.
Topics: Animals; Carcinoma, Squamous Cell; Cell Line; Diglycerides; Epidermal Growth Factor; ErbB Receptors; Fibroblasts; Glycerides; Humans; Mice; Mitosis; Phorbol Esters; Phorbols; Phospholipids; Phosphoproteins; Phosphorylation; Protein Kinases; Protein-Tyrosine Kinases; Receptors, Cell Surface; Tetradecanoylphorbol Acetate | 1985 |
EGF receptor affinity is regulated by intracellular calcium and protein kinase C.
Topics: Animals; Calcimycin; Calcium; Carcinoma, Squamous Cell; Cell Line; Egtazic Acid; Epidermal Growth Factor; ErbB Receptors; Phosphorylation; Protein Kinase C; Protein Kinases; Rats; Receptors, Cell Surface; Tetradecanoylphorbol Acetate | 1985 |
Inhibition of the apparent affinity of the epidermal growth factor receptor caused by phorbol diesters correlates with phosphorylation of threonine-654 but not other sites on the receptor.
Topics: Amiloride; Amino Acids; Binding Sites; Carcinoma, Squamous Cell; Cell Line; ErbB Receptors; Humans; Phorbols; Phosphopeptides; Phosphorylation; Receptors, Cell Surface; Tetradecanoylphorbol Acetate; Threonine | 1986 |
[Regulation of EGF receptor by tumor promoters].
Topics: Animals; Carcinoma, Squamous Cell; Cell Line; ErbB Receptors; Fibroblasts; Humans; Mice; Mouth Neoplasms; Pancreatic Neoplasms; Phosphorylation; Protein Kinase C; Receptors, Cell Surface; Tetradecanoylphorbol Acetate | 1986 |
Activation of 45Ca2+ influx and 22Na+/H+ exchange by epidermal growth factor and vanadate in A431 cells is independent of phosphatidylinositol turnover and is inhibited by phorbol ester and diacylglycerol.
Topics: Calcium; Calcium Radioisotopes; Carcinoma, Squamous Cell; Cell Line; Diglycerides; Epidermal Growth Factor; Humans; Kinetics; Phosphatidylinositols; Protons; Sodium; Sodium Radioisotopes; Tetradecanoylphorbol Acetate; Vanadates; Vanadium | 1986 |
Effect of epidermal growth factor and 12-O-tetradecanoylphorbol-13-acetate on the phosphorylation of soluble acidic proteins in A431 epidermoid carcinoma cells.
Topics: Bucladesine; Carcinoma, Squamous Cell; Cells, Cultured; Cytosol; Epidermal Growth Factor; Humans; Molecular Weight; Phorbols; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein Kinases; Proteins; Tetradecanoylphorbol Acetate | 1986 |
Effect of recombinant monokines, lymphokines, and other agents on clonal proliferation of human lung cancer cell lines.
Topics: Calcitriol; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cell Division; Cell Line; Clone Cells; Colony-Stimulating Factors; Dimethyl Sulfoxide; Drug Synergism; Humans; Interleukin-1; Lung Neoplasms; Lymphokines; Monokines; Proteins; Receptors, Cell Surface; Receptors, Tumor Necrosis Factor; Recombinant Proteins; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Stem Cell Assay | 1987 |
Inducible binding of a factor to the c-fos enhancer.
Topics: Calcium; Carcinoma, Squamous Cell; Cell Line; DNA-Binding Proteins; DNA, Neoplasm; Enhancer Elements, Genetic; Epidermal Growth Factor; Genes, Regulator; HeLa Cells; Humans; Neoplasm Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1986 |
Progressive dysplasia and aneuploidy are hallmarks of mouse skin papillomas: relevance to malignancy.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aneuploidy; Animals; Carcinoma, Squamous Cell; Cell Nucleus; Mice; Mice, Inbred Strains; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1987 |
Tumor progression in Sencar mouse skin as a function of initiator dose and promoter dose, duration, and type.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anthracenes; Carcinogens; Carcinoma, Squamous Cell; Dose-Response Relationship, Drug; Female; Mice; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1988 |
Expression pattern of a gene for a secreted metalloproteinase during late stages of tumor progression.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Amino Acid Sequence; Animals; Carcinoma, Squamous Cell; Cloning, Molecular; DNA, Neoplasm; Female; Gene Amplification; Gene Rearrangement; Immunoblotting; Matrix Metalloproteinase 3; Metalloendopeptidases; Mice; Molecular Sequence Data; Multigene Family; Neoplasm Proteins; Papilloma; Peptide Hydrolases; Plasmids; RNA, Neoplasm; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1988 |
Regulation of the epidermal growth factor receptor phosphorylation state by sphingosine in A431 human epidermoid carcinoma cells.
Topics: Carcinoma, Squamous Cell; Dose-Response Relationship, Drug; ErbB Receptors; Humans; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphorylation; Protein Kinase C; Sphingosine; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured | 1988 |
Growth factor- and phorbol ester-induced changes in cell morphology analyzed by digital image processing.
Topics: Actins; Animals; Carcinoma, Squamous Cell; Cell Line; Cell Membrane; Cell Movement; Epidermal Growth Factor; Fibroblasts; Growth Substances; Humans; Image Processing, Computer-Assisted; Insulin; Somatomedins; Temperature; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1988 |
The epidermal growth factor-induced calcium signal in A431 cells.
Topics: Aminoquinolines; Blood; Calcium; Carcinoma, Squamous Cell; Cell Line; Epidermal Growth Factor; Humans; Lanthanum; Manganese; Mathematics; Membrane Potentials; Potassium; Protein Kinase C; Tetradecanoylphorbol Acetate | 1986 |
Effects of epidermal growth factor on transferrin receptor phosphorylation and surface expression in malignant epithelial cells.
Topics: Animals; Antibodies; Binding Sites; Carcinoma, Squamous Cell; Cell Line; Cell Transformation, Neoplastic; Epidermal Growth Factor; Epithelium; ErbB Receptors; Methionine; Phosphorylation; Receptors, Transferrin; Tetradecanoylphorbol Acetate; Vanadates | 1987 |
Protein kinase C-mediated feed back inhibition of the Ca2+ response at the EGF receptor.
Topics: Calcium; Carcinoma, Squamous Cell; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Feedback; Inositol Phosphates; Kinetics; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1987 |
The mRNA coding for the secreted protease transin is expressed more abundantly in malignant than in benign tumors.
Topics: Animals; Carcinoma, Squamous Cell; Cell Transformation, Viral; Endopeptidases; Gene Expression Regulation; Matrix Metalloproteinase 3; Mice; Neoplasm Proteins; Neoplasms, Experimental; Papilloma; RNA, Messenger; RNA, Neoplasm; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1986 |
Ionizing radiation as an initiator: effects of proliferation and promotion time on tumor incidence in mice.
Topics: Animals; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cocarcinogenesis; Dose-Response Relationship, Radiation; Female; Mice; Neoplasms, Radiation-Induced; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1987 |
Ionizing radiation as an initiator in the mouse two-stage model of skin tumor formation.
Topics: Animals; Carcinogens; Carcinoma, Squamous Cell; Cocarcinogenesis; Female; Mice; Neoplasms, Experimental; Papilloma; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; X-Rays | 1986 |
Enhancement of two-stage skin carcinogenesis by exposure of distant skin to UV radiation.
Topics: Animals; Carcinoma, Squamous Cell; Cocarcinogenesis; Female; Fibrosarcoma; Immune Tolerance; Mice; Mice, Inbred C3H; Neoplasms, Radiation-Induced; Papilloma; Phorbols; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Ultraviolet Rays | 1985 |
Modulation of type-IV procollagen and laminin production in A431 human squamous epidermoid carcinoma cells by 12-O-tetradecanoylphorbol-13-acetate (TPA) and epidermal growth factor (EGF).
Topics: Basement Membrane; Carcinogens; Carcinoma, Squamous Cell; Cell Division; Cell Line; Drug Synergism; Epidermal Growth Factor; Epithelium; Extracellular Matrix; Humans; Laminin; Neoplasm Proteins; Phorbols; Procollagen; Tetradecanoylphorbol Acetate; Time Factors | 1985 |
Two-stage tumor promotion in mouse skin: an alternative interpretation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cocarcinogenesis; Croton Oil; Fluocinolone Acetonide; Mice; Mice, Inbred Strains; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tosylphenylalanyl Chloromethyl Ketone; Tretinoin | 1985 |
Increase in urokinase plasminogen activator mRNA synthesis in human carcinoma cells is a primary effect of the potent tumor promoter, phorbol myristate acetate.
Topics: Carcinoma, Squamous Cell; Cell Division; Cell Line; Cycloheximide; DNA Replication; Genes; Humans; Kinetics; Phorbols; Platelet-Derived Growth Factor; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Urokinase-Type Plasminogen Activator | 1986 |
[Tissue polypeptide antigen in gynecological cancer].
Topics: Adenocarcinoma; Adult; Carcinoembryonic Antigen; Carcinoma, Squamous Cell; Female; Humans; Neoplasm Proteins; Ovarian Neoplasms; Phorbols; Tetradecanoylphorbol Acetate; Uterine Cervical Neoplasms; Uterine Neoplasms | 1985 |
Normal and transformed human prokeratinocytes express divergent effects of a tumor promoter on cell cycle-mediated control of proliferation and differentiation.
Topics: Adult; Carcinoma, Squamous Cell; Cell Cycle; Cell Differentiation; Cell Division; Cells, Cultured; Humans; Infant, Newborn; Phorbols; Skin; Tetradecanoylphorbol Acetate | 1985 |