tetradecanoylphorbol acetate has been researched along with Carcinogenesis in 52 studies
Timeframe | Studies, this research(%) | All Research% |
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pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 40 (76.92) | 24.3611 |
2020's | 12 (23.08) | 2.80 |
Authors | Studies |
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González-Rodríguez, M; Hiihtola, L; Järvinen, TAH; Junttila, IS; Kummola, L; Määttä, J; Parviainen, L; Pemmari, T; Salomaa, T; Salonen, N; Vähätupa, M | 1 |
Araki, K; Hasegawa, Y; Isogai, E; Okumura, K; Saito, M; Tokunaga, Y; Wakabayashi, Y | 1 |
Dang, Y; Guo, C; Li, Y; Liang, Y; Liu, M; Shi, Y; Wang, C; Xiang, W; Xu, P; Ye, X; Zhang, X | 1 |
Ghadi, DS; Joshi, P; Waghmare, SK | 1 |
Akira, S; Morisaka, H; Sano, S; Takaishi, M | 1 |
Chou, P; Dina Kuo, HC; Kong, AN; Mary Peter, R; Ramirez, CN; Sargsyan, D; Sarwar, MS; Shannar, A; Su, X; Wang, Y; Wu, R; Yang, Y; Yin, R | 1 |
Abd Hamid, R; Md Roduan, MR; Mohtarrudin, N | 1 |
Dahlhoff, M; Fröhlich, T; Goebeler, M; Hoesl, C; Hundt, JE; Kneitz, H; Schneider, MR; Wolf, R | 1 |
Järvinen, TAH; Junttila, I; Pemmari, T; Pesu, M; Vähätupa, M | 1 |
Bagnoli, JW; Blum, H; Chen-Wichmann, L; Cusan, M; Enard, W; Greif, PA; Hartmann, L; Hiddemann, W; Jeremias, I; Kerbs, P; Krebs, S; Leubolt, G; Redondo Monte, E; Theurich, S; Vick, B; Wichmann, C; Wilding, A | 1 |
Ahmed, F; Bano, S; Chaudhary, SC; Khan, F; Samim, M | 1 |
Bian, LH; Gao, HW; Gong, F; Gong, L; Ji, SP; Li, JP; Li, SB; Li, W; Luo, Q; Tan, YX; Wan, LM; Wei, CW; Yun, ZM; Zhang, SK; Zhang, X; Zhong, H; Zhuo, HL | 1 |
Hu, X; Wang, L; Zhang, L; Zhang, T | 1 |
Hu, X; Li, J; Li, S; Zhang, F; Zhang, K; Zhao, W | 1 |
Ben-David, Y; Gajendran, B; Hao, X; Liu, W; Sample, KM; Varier, KM; Wang, C; Yao, Y; Zacksenhaus, E | 1 |
Chugh, NA; Kaur, N; Koul, A | 1 |
Christensen, R; Füchtbauer, AC; Füchtbauer, EM; Gunnarsson, A; Jensen, UB; Owens, DM; Ramsing, M | 1 |
Anguish, LJ; Coonrod, SA; Horibata, S; McElwee, JL; McLean, D; Mohanan, S; Mukai, C; Sams, K; Yan, A | 1 |
Hamid, RA; Md Roduan, MR; Mohtarrudin, N; Sulaiman, H | 1 |
Aguilar-Pimentel, JA; Beck, PJ; Fuchs, H; Gailus-Durner, V; Garman, KA; Hrabe de Angelis, M; Lee, YG; Ollert, M; Riegel, AT; Schmidt, MO; Schmidt-Weber, C; Tan, M; Tassi, E; Wellstein, A; Zuo, C | 1 |
Liu, P; Wang, D | 1 |
Ahn, JS; Cha-Molstad, H; Choi, TW; Han, HJ; Hong, JT; Hwang, J; Kim, BY; Kim, HJ; Kwon, YT; Lee, HG; Lee, KH; Lee, Y; Mun, J; Soung, NK | 1 |
Cleary, MP; Hao, J; Landers, VD; Li, B; Li, Q; Liu, L; Mandal, A; Morris, RJ; Rao, E; Sun, Y; Suttles, J; Zeng, J; Zhang, Y | 1 |
Carson, DA; Li, S; Liu, SS; Lu, D; Song, J; Su, Z; Sun, Q; Wang, Z; Wei, L; Xia, Y; Yu, S; Zhao, L; Zhou, L | 1 |
Al Habeeb, A; Bai, X; Cho, HR; Liu, M; Lu, C; Post, A; Wang, Y; Xiang, YY | 1 |
Furukawa, F; Kawabe, M; Numano, T; Suguro, M; Taguchi, F; Tsutsumi, H; Urano, K | 1 |
Hanausek, M; Junco, JJ; Kowalczyk, MC; Kowalczyk, P; Slaga, TJ; Tolstykh, O; Walaszek, Z | 1 |
Ichiishi, E; Iida, A; Kapadia, GJ; Konoshima, T; Rao, GS; Sridhar, R; Suzuki, N; Takasaki, M; Tokuda, H | 1 |
Angel, JM; Beltran, L; Blando, J; Checkley, LA; Cho, J; DiGiovanni, J; Hursting, SD; Rho, O | 1 |
Ali, F; Khan, AQ; Khan, R; Lateef, MA; Maqbool, T; Sultana, S | 1 |
Ali, F; Hamiza, OO; Hasan, SK; Khan, AQ; Khan, R; Lateef, A; Rehman, MU; Sultana, S; Tahir, M | 1 |
Hogg, N; McNeill, E | 1 |
He, YY; Ming, M; Qiang, L; Zhao, B | 1 |
Maurer, M; Metz, M; Siebenhaar, F | 1 |
Becker, K; Kaina, B; Thomas, AD | 1 |
Chang, L; Drachenberg, DM; Klos, KS; Leung, CT; Luxton, GW; Schwertfeger, KL; Warmka, JK; Wattenberg, EV | 1 |
Christiansen, H; Dittmann, K; Frommhold, A; Hahn, H; Heß, I; König, S; Lühder, F; Nitzki, F; Reifenberger, J; Schulz-Schaeffer, W; Uhmann, A; Zabel, S | 1 |
Cha, IH; Cho, SB; Choi, EJ; Kim, J; Kim, KY; Zhang, X; Zheng, Z; Zhu, L | 1 |
Becker, JC; Zur Hausen, A | 1 |
Bernabéu, C; del Castillo, G; Langa, C; Martín-Villar, E; Pérez-Gómez, E; Quintanilla, M; Renart, J; Sánchez-Blanco, E; Valbuena-Diez, AC | 1 |
Chen, C; Fan, F; Lin, C; Liu, Y; Liu, Z; Lu, Y; Shen, C; Sun, L; Tao, Y; Wang, A; Wang, S; Wei, Z; Wu, H; Zhao, L; Zhu, P; Zhu, Z | 1 |
Amjad, A; Cai, X; Chen, H; Chen, T; Dang, Y; Fu, J; Gao, X; He, J; Huang, Q; Ji, L; Jiang, Z; Jing, T; Li, K; Li, L; Li, X; Liu, J; Liu, T; Moses, RE; Shi, K; Song, D; Tong, L; Xiao, J; Xu, W; Yan, W; Yang, C; Yang, X; Yao, L; Zhai, W; Zhang, J | 1 |
Carbajal, S; Cho, J; DiGiovanni, J; Junco, J; Rho, O; Siegel, D; Slaga, TJ | 1 |
Brandi, G; Bucchini, A; De Santi, M; Fanelli, M; Giamperi, L; Giomaro, G; Schiavano, GF | 1 |
Bratton, SB; Cho, J; Dao, CK; DiGiovanni, J; Fischer, SM; Kohno, S; Lago, CU; Lee, S; Mills, EM; Nikawa, T; Nowinski, SM; Rho, O; Riley, CL; Rundhaug, JE; Solmonson, A; Wright, CW | 1 |
Beck, A; Fletcher, S; Goldstein, J; Horsley, V; Lin, S; Roberts, N; Roth, E; Suárez-Fariñas, M; Tadeu, A; Wu, C; Zeiss, C; Zwick, R | 1 |
Bauer, SJ; Havighurst, TC; Kim, K; Singh, A; Verma, AK; Wheeler, DL | 1 |
Heino, J; Jokinen, J; Lilja, J; Niskanen, H; Rappu, P; Salmela, M; Taipalus, E | 1 |
Hermeking, H; Lodygin, D; Verdoodt, B; Winter, M | 1 |
Hu, YQ; Wang, J; Wu, JH | 1 |
Balmain, A; Del Rosario, R; Ginzinger, D; Halliwill, KD; Kang, HC; Quigley, DA | 1 |
Alam, MS; Athar, M; Chaudhary, SC; Siddiqui, MS | 1 |
52 other study(ies) available for tetradecanoylphorbol acetate and Carcinogenesis
Article | Year |
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IL-13Rα1 Suppresses Tumor Progression in Two-Stage Skin Carcinogenesis Model by Regulating Regulatory T Cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogenesis; Carcinogens; Interleukin-13; Interleukin-13 Receptor alpha1 Subunit; Mice; Mice, Knockout; Papilloma; Skin Neoplasms; T-Lymphocytes, Regulatory; Tetradecanoylphorbol Acetate | 2022 |
Functional Polymorphism in Pak1-3' Untranslated Region Alters Skin Tumor Susceptibility by Alternative Polyadenylation.
Topics: 3' Untranslated Regions; Animals; Carcinogenesis; Mice; Mice, Inbred Strains; p21-Activated Kinases; Polyadenylation; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2022 |
P2RY6 Has a Critical Role in Mouse Skin Carcinogenesis by Regulating the YAP and β-Catenin Signaling Pathways.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; beta Catenin; Carcinogenesis; Hyperplasia; Keratinocytes; Mice; Receptors, Purinergic P2; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Wnt Signaling Pathway; YAP-Signaling Proteins | 2022 |
Isolation of cancer stem cells from skin squamous cell carcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogenesis; Carcinogens; Carcinoma, Squamous Cell; Disease Models, Animal; Humans; Mice; Neoplastic Stem Cells; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2022 |
Keratinocyte Regnase-1, a Downregulator of Skin Inflammation, Contributes to Protection against Tumor Promotion by Limiting Cyclooxygenase-2 Expression.
Topics: Acetates; Animals; Carcinogenesis; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cyclooxygenase 2; Dermatitis; Humans; Inflammation; Keratinocytes; Lithostathine; Mice; RNA, Messenger; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2023 |
The environmental carcinogen benzo[a]pyrene regulates epigenetic reprogramming and metabolic rewiring in a two-stage mouse skin carcinogenesis model.
Topics: Animals; Benzo(a)pyrene; Carcinogenesis; Carcinogens, Environmental; Epigenesis, Genetic; Melatonin; Mice; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2023 |
Modulation of cancer signalling pathway(s) in two -stage mouse skin tumorigenesis by annonacin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogenesis; Carcinogens; Female; Furans; Kidney; Lactones; Liver; Mice; Mice, Inbred ICR; Signal Transduction; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2019 |
The transmembrane protein LRIG2 increases tumor progression in skin carcinogenesis.
Topics: Aged; Aged, 80 and over; Animals; Carcinogenesis; Cell Differentiation; Cell Line, Tumor; Disease Progression; Epidermis; ErbB Receptors; Homeostasis; Humans; Hyperplasia; Inflammation; Membrane Glycoproteins; Mice, Inbred C57BL; Phenotype; Protein Binding; Skin Neoplasms; Tetradecanoylphorbol Acetate; Thrombospondins | 2019 |
Chemical-Induced Skin Carcinogenesis Model Using Dimethylbenz[a]Anthracene and 12-O-Tetradecanoyl Phorbol-13-Acetate (DMBA-TPA).
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogenesis; Carcinogens; Female; Humans; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2019 |
ZBTB7A prevents RUNX1-RUNX1T1-dependent clonal expansion of human hematopoietic stem and progenitor cells.
Topics: Animals; Bone Marrow; Carcinogenesis; Cell Cycle Checkpoints; Cell Differentiation; Cell Line, Tumor; Cell Lineage; Core Binding Factor Alpha 2 Subunit; Deoxyglucose; DNA-Binding Proteins; Gene Knockout Techniques; Glycolysis; Hematopoiesis; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid, Acute; Loss of Function Mutation; Mice; Myeloid Progenitor Cells; Oncogene Proteins, Fusion; RUNX1 Translocation Partner 1 Protein; Tetradecanoylphorbol Acetate; Transcription Factors; Xenograft Model Antitumor Assays | 2020 |
Enhancement of the cancer inhibitory effect of the bioactive food component resveratrol by nanoparticle based delivery.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Apoptosis; Biological Availability; Carcinogenesis; Inflammation; Mice; Nanoparticles; Oxidative Stress; Phytochemicals; Resveratrol; Skin; Tetradecanoylphorbol Acetate | 2020 |
Heparanase Facilitates PMA-Induced Megakaryocytic Differentiation in K562 Cells via Interleukin 6/STAT3 Pathway.
Topics: Carcinogenesis; Cell Differentiation; Extracellular Matrix; Feedback, Physiological; Fetal Blood; Glucuronidase; Heparitin Sulfate; Humans; Interleukin-6; K562 Cells; Leukemia, Erythroblastic, Acute; Megakaryocytes; Signal Transduction; STAT3 Transcription Factor; Tetradecanoylphorbol Acetate | 2020 |
β-Elemene inhibits 7,12-dimethylbenz(a)anthracene/12-O-tetradecanoylphorbol-13-acetate-induced skin tumorigenesis through suppression of NF-κB-associated signaling events in the mouse skin model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogenesis; Carcinogens; Disease Models, Animal; Mice; NF-kappa B; Sesquiterpenes; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2020 |
The role of the Epstein-Barr virus-encoded BARF1 gene expressed in human gastric epithelial cells.
Topics: Animals; Carcinogenesis; Disease Models, Animal; Epithelial Cells; Gastric Mucosa; Herpesvirus 4, Human; Humans; Mice; Severe Combined Immunodeficiency; Tetradecanoylphorbol Acetate; Transfection; Viral Proteins | 2020 |
Ubash3b promotes TPA-mediated suppression of leukemogenesis through accelerated downregulation of PKCδ protein.
Topics: Carcinogenesis; Cell Line, Tumor; Down-Regulation; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Leukemic; Humans; Leukemia; Neoplasm Proteins; Protein Kinase C-delta; Protein Tyrosine Phosphatases; Tetradecanoylphorbol Acetate | 2021 |
Folic Acid Modulates DMBA/TPA-Induced Changes in Skin of Mice: A Study Relevant to Carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogenesis; Carcinogens; Epidermis; Folic Acid; Mice; Mice, Inbred BALB C; Ornithine Decarboxylase; Proliferating Cell Nuclear Antigen; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Vitamin B Complex | 2018 |
Constitutive transgene expression of Stem Cell Antigen-1 in the hair follicle alters the sensitivity to tumor formation and progression.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Ly; Carcinogenesis; Clone Cells; Colony-Forming Units Assay; Disease Progression; Female; Hair Follicle; Integrases; Membrane Proteins; Mice, Inbred C57BL; Mice, Transgenic; Morphogenesis; Skin; Tetradecanoylphorbol Acetate; Transgenes | 2017 |
PAD2 overexpression in transgenic mice augments malignancy and tumor-associated inflammation in chemically initiated skin tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogenesis; Carcinogens; Disease Progression; Gene Expression Regulation, Neoplastic; Humans; Inflammation; Male; Mice; Mice, Transgenic; Papilloma; Protein-Arginine Deiminase Type 2; Protein-Arginine Deiminases; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Up-Regulation | 2017 |
Annona muricata leaves extracts prevent DMBA/TPA-induced skin tumorigenesis via modulating antioxidants enzymes system in ICR mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Annona; Antioxidants; Carcinogenesis; Furans; Lactones; Male; Mice, Inbred ICR; Plant Extracts; Plant Leaves; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2017 |
The Role of Fibroblast Growth Factor-Binding Protein 1 in Skin Carcinogenesis and Inflammation.
Topics: Animals; Bone Marrow; Bone Marrow Transplantation; Carcinogenesis; Carcinogens; Carrier Proteins; Female; Humans; Inflammation; Intercellular Signaling Peptides and Proteins; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neoplasms, Experimental; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Up-Regulation; Water Loss, Insensible; Wound Healing | 2018 |
Ingenol-3-Angelate Suppresses Growth of Melanoma Cells and Skin Tumor Development by Downregulation of NF-κB-Cox2 Signaling.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Apoptosis Regulatory Proteins; Carcinogenesis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclooxygenase 2; Diterpenes; Down-Regulation; Epidermis; Female; Hyperplasia; Inflammation; Melanoma; Mice, Inbred ICR; NF-kappa B; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2018 |
A novel tubulin inhibitor STK899704 induces tumor regression in DMBA/TPA-induced skin carcinogenesis model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antimetabolites, Antineoplastic; Benzofurans; Carcinogenesis; Colchicine; Disease Models, Animal; Fluorouracil; Male; Mice; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tubulin; Tubulin Modulators | 2018 |
Epidermal FABP Prevents Chemical-Induced Skin Tumorigenesis by Regulation of TPA-Induced IFN/p53/SOX2 Pathway in Keratinocytes.
Topics: Animals; Carcinogenesis; Epidermis; Fatty Acid-Binding Proteins; Gene Expression Regulation, Neoplastic; Interferon-beta; Keratinocytes; Male; Mice; Mice, Inbred C57BL; Neoplasm Proteins; Neoplasms, Experimental; RNA, Neoplasm; Skin Neoplasms; SOXB1 Transcription Factors; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53 | 2018 |
Tumor promoter TPA activates Wnt/β-catenin signaling in a casein kinase 1-dependent manner.
Topics: Animals; Axin Protein; beta Catenin; Carcinogenesis; Carcinogens; Casein Kinase 1 epsilon; Casein Kinase Idelta; Cell Line, Tumor; Disease Models, Animal; Fibroblasts; HEK293 Cells; Humans; Low Density Lipoprotein Receptor-Related Protein-6; Mice; Phosphorylation; Protein Stability; Purines; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factor 4; Wnt Proteins; Wnt Signaling Pathway | 2018 |
XB130 deficiency enhances carcinogen-induced skin tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adaptor Proteins, Signal Transducing; Animals; Carcinogenesis; Carcinogens; Cell Proliferation; Female; Genes, Tumor Suppressor; Inflammation; Male; Mice; Mice, Knockout; Microfilament Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2019 |
Tumor promotion by 12-O-tetradecanoylphorbol-13-acetate in an ultra-short-term skin carcinogenesis bioassay using rasH2 mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biological Assay; Carcinogenesis; Dose-Response Relationship, Drug; Female; Humans; Mice; Mice, Transgenic; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2013 |
Effects of combined phytochemicals on skin tumorigenesis in SENCAR mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogenesis; Cell Proliferation; Cyclooxygenase 2; Female; Gene Expression Regulation, Neoplastic; Glucaric Acid; Humans; Interleukin-6; Mice; Mice, Inbred SENCAR; Phytochemicals; Resveratrol; Skin Neoplasms; Stilbenes; Tetradecanoylphorbol Acetate; Triterpenes; Ursolic Acid | 2013 |
Chemoprevention of skin cancer: effect of Lawsonia inermis L. (Henna) leaf powder and its pigment artifact, lawsone in the Epstein- Barr virus early antigen activation assay and in two-stage mouse skin carcinogenesis models.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Cutaneous; Administration, Oral; Animals; Antigens, Viral; Antineoplastic Agents, Phytogenic; B-Lymphocytes; Carcinogenesis; Cell Line, Tumor; Female; Herpesvirus 4, Human; Humans; Lawsonia Plant; Male; Naphthoquinones; Papilloma; Plant Extracts; Plant Leaves; Skin Neoplasms; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 2013 |
Metformin inhibits skin tumor promotion in overweight and obese mice.
Topics: Adenylate Kinase; Adiponectin; Animals; Body Weight; Carcinogenesis; Carcinoma, Squamous Cell; Diet; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Insulin; Insulin-Like Growth Factor I; Leptin; Mechanistic Target of Rapamycin Complex 1; Metformin; Mice; Mice, Obese; Multiprotein Complexes; Neoplasms, Experimental; Obesity; Overweight; Papilloma; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Sirolimus; Skin Neoplasms; Tetradecanoylphorbol Acetate; TOR Serine-Threonine Kinases | 2014 |
Assessment of Augmented Immune Surveillance and Tumor Cell Death by Cytoplasmic Stabilization of p53 as a Chemopreventive Strategy of 3 Promising Medicinal Herbs in Murine 2-Stage Skin Carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antioxidants; Apoptosis; Calendula; Carcinogenesis; Cell Cycle Checkpoints; Cell Movement; Cell Proliferation; Chemoprevention; Eclipta; Female; Free Radicals; Immunologic Surveillance; Inflammation; Langerhans Cells; Mice; NF-kappa B; Phytotherapy; Plant Extracts; Proliferating Cell Nuclear Antigen; Signal Transduction; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Trigonella; Tumor Suppressor Protein p53 | 2014 |
Silibinin inhibits tumor promotional triggers and tumorigenesis against chemically induced two-stage skin carcinogenesis in Swiss albino mice: possible role of oxidative stress and inflammation.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Carcinogenesis; Catalase; Cell Transformation, Neoplastic; Chemoprevention; Cyclooxygenase 2; Down-Regulation; Female; Glucosephosphate Dehydrogenase; Inflammation; Interleukin-1beta; Interleukin-6; Lipid Peroxidation; Mice; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidative Stress; Silybin; Silymarin; Skin; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Up-Regulation; Vascular Endothelial Growth Factor A | 2014 |
S100A9 has a protective role in inflammation-induced skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Calgranulin A; Calgranulin B; Carcinogenesis; Cell Transformation, Neoplastic; Dimerization; Female; Gene Deletion; Gene Expression Regulation, Neoplastic; Inflammation; Keratinocytes; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neutrophils; Skin Neoplasms; T-Lymphocytes; Tetradecanoylphorbol Acetate | 2014 |
Mammalian SIRT2 inhibits keratin 19 expression and is a tumor suppressor in skin.
Topics: Animals; Antigens, CD34; Apoptosis; Carcinogenesis; Carcinoma, Squamous Cell; Cell Proliferation; DNA Repair; Down-Regulation; Gene Expression Regulation, Neoplastic; Humans; Keratin-15; Keratin-19; Keratinocytes; Membrane Proteins; Mice; Mice, Knockout; RNA, Small Interfering; Sirtuin 2; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Burden; Up-Regulation | 2014 |
Mast cells protect from skin tumor development and limit tumor growth during cutaneous de novo carcinogenesis in a Kit-dependent mouse model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adoptive Transfer; Animals; Carcinogenesis; Cell Count; Cell Degranulation; Cytoprotection; Disease Models, Animal; Female; Granulocytes; Macrophages; Mast Cells; Mice; Proto-Oncogene Proteins c-kit; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Burden | 2014 |
Does increase in DNA repair allow "tolerance-to-insult" in chemical carcinogenesis? Skin tumor experiments with MGMT-overexpressing mice.
Topics: Animals; Carcinogenesis; Disease Resistance; DNA Modification Methylases; DNA Repair; DNA Repair Enzymes; Gene Expression; Humans; Methylnitrosourea; Mice; Mice, Transgenic; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Suppressor Proteins | 2014 |
Building bridges toward invasion: tumor promoter treatment induces a novel protein kinase C-dependent phenotype in MCF10A mammary cell acini.
Topics: Acinar Cells; Actins; Breast Neoplasms; Cadherins; Carcinogenesis; Cell Aggregation; Cell Death; Cell Line; Cell Polarity; Female; Humans; Laminin; Mammary Glands, Human; Mitosis; Neoplasm Invasiveness; Phenotype; Protein Kinase C; Tetradecanoylphorbol Acetate; Time Factors | 2014 |
DMBA/TPA treatment is necessary for BCC formation from patched deficient epidermal cells in Ptch(flox/flox)CD4Cre(+/-) mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alleles; Animals; Carcinogenesis; Carcinogens; Carcinoma, Basal Cell; CD4-Positive T-Lymphocytes; Disease Models, Animal; Epidermis; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Mutation; Patched Receptors; Patched-1 Receptor; Proto-Oncogene Proteins p21(ras); Receptors, Cell Surface; Signal Transduction; Skin Neoplasms; Stem Cells; Tetradecanoylphorbol Acetate | 2014 |
Apoptotic effect of pheophorbide a-mediated photodynamic therapy on DMBA/TPA-induced mouse papillomas.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogenesis; Caspase 3; Chlorophyll; Female; Immunohistochemistry; In Situ Nick-End Labeling; Mice, Hairless; Papilloma; Photochemotherapy; Photosensitizing Agents; Proliferating Cell Nuclear Antigen; Tetradecanoylphorbol Acetate | 2015 |
Cells of origin in skin cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogenesis; Carcinoma, Basal Cell; CD4-Positive T-Lymphocytes; Epidermis; Patched Receptors; Receptors, Cell Surface; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2014 |
Soluble endoglin antagonizes Met signaling in spindle carcinoma cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, CD; Carcinogenesis; Cell Movement; Cell Proliferation; DNA, Complementary; Endoglin; Enzyme Activation; Female; HEK293 Cells; Hepatocyte Growth Factor; Humans; MAP Kinase Signaling System; Mice; Mice, Nude; Mitogen-Activated Protein Kinases; Prognosis; Proto-Oncogene Proteins c-met; Receptors, Cell Surface; Sarcoma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transfection; Transforming Growth Factor beta1; Tumor Cells, Cultured | 2015 |
Cancer-promoting effect of capsaicin on DMBA/TPA-induced skin tumorigenesis by modulating inflammation, Erk and p38 in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Capsaicin; Carcinogenesis; Cyclooxygenase 2; Female; Hyperplasia; Inflammation; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Mice; Mice, Inbred ICR; NF-kappa B; Nitric Oxide Synthase Type II; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Up-Regulation | 2015 |
REGγ is critical for skin carcinogenesis by modulating the Wnt/β-catenin pathway.
Topics: Animals; Autoantigens; Carcinogenesis; Carcinogens; Cell Line; Cell Proliferation; Cyclin D1; Gene Knockdown Techniques; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Keratinocytes; Mice; Mice, Knockout; p38 Mitogen-Activated Protein Kinases; Proteasome Endopeptidase Complex; Proto-Oncogene Proteins c-myc; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Wnt Signaling Pathway | 2015 |
Effect of Combined Treatment with Ursolic Acid and Resveratrol on Skin Tumor Promotion by 12-O-Tetradecanoylphorbol-13-Acetate.
Topics: Animals; Anticarcinogenic Agents; Carcinogenesis; Cell Nucleus; Cell Proliferation; Cytosol; Female; Inflammation; Male; Mice; Mice, Inbred ICR; Protein Binding; Resveratrol; Signal Transduction; Skin; Skin Neoplasms; Stilbenes; Tetradecanoylphorbol Acetate; Triterpenes; Ursolic Acid | 2015 |
Inhibition of Breast Cancer Cell Proliferation and In Vitro Tumorigenesis by a New Red Apple Cultivar.
Topics: Anthocyanins; Antineoplastic Agents; Breast Neoplasms; Carcinogenesis; Cell Division; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Fruit and Vegetable Juices; G2 Phase; Humans; Malus; MCF-7 Cells; Microtubule-Associated Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Polyphenols; Tetradecanoylphorbol Acetate | 2015 |
Mitochondrial uncoupling links lipid catabolism to Akt inhibition and resistance to tumorigenesis.
Topics: Animals; Carcinogenesis; Carcinogens; Cell Proliferation; Flow Cytometry; Gene Ontology; Humans; Immunoblotting; Ion Channels; Keratinocytes; Lipid Metabolism; Metabolome; Metabolomics; Mice; Mice, Transgenic; Mitochondria; Mitochondrial Proteins; Neoplasms, Experimental; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Skin Neoplasms; Tetradecanoylphorbol Acetate; Uncoupling Protein 3 | 2015 |
Loss of endogenous Nfatc1 reduces the rate of DMBA/TPA-induced skin tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogenesis; Carcinogens; Cytochrome P-450 CYP2E1; DNA Damage; Hair Follicle; Keratinocytes; Mice; Mice, Knockout; NFATC Transcription Factors; Papilloma; Skin; Skin Neoplasms; Stem Cells; Tetradecanoylphorbol Acetate | 2015 |
Genetic deletion of TNFα inhibits ultraviolet radiation-induced development of cutaneous squamous cell carcinomas in PKCε transgenic mice via inhibition of cell survival signals.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogenesis; Carcinogens; Carcinoma, Squamous Cell; Cell Survival; Female; Male; Mice; Mice, Knockout; Mice, Transgenic; Protein Kinase C-epsilon; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Ultraviolet Rays | 2016 |
Tumor promoter PMA enhances kindlin-2 and decreases vimentin recruitment into cell adhesion sites.
Topics: Animals; Carcinogenesis; Cell Adhesion; Cell Line; Cricetinae; Cytoskeleton; Integrin alpha1beta1; Membrane Proteins; Neoplasm Proteins; Protein Transport; Pseudopodia; Tetradecanoylphorbol Acetate; Vimentin | 2016 |
Deletion of 14-3-3σ sensitizes mice to DMBA/TPA-induced papillomatosis.
Topics: 14-3-3 Proteins; 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogenesis; Cell Differentiation; Cell Proliferation; Codon, Nonsense; Disease Models, Animal; Down-Regulation; Epidermal Cells; Epidermis; Exons; Female; Gain of Function Mutation; Gene Deletion; Hair Follicle; Heterozygote; Immunohistochemistry; Integrases; Keratinocytes; Male; Mice; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2016 |
Administration of resveratrol enhances cell-cycle arrest followed by apoptosis in DMBA-induced skin carcinogenesis in male Wistar rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Apoptosis; Carcinogenesis; Cell Cycle Checkpoints; Male; Rats; Rats, Wistar; Resveratrol; Skin Neoplasms; Stilbenes; Tetradecanoylphorbol Acetate | 2016 |
Panx3 links body mass index and tumorigenesis in a genetically heterogeneous mouse model of carcinogen-induced cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Mass Index; Carcinogenesis; Carcinogens; Connexins; Crosses, Genetic; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Genetic Predisposition to Disease; Humans; Inflammation; Lipid Metabolism; Male; Mice; Mice, Inbred Strains; Quantitative Trait Loci; Sex Factors; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2016 |
Geraniol inhibits murine skin tumorigenesis by modulating COX-2 expression, Ras-ERK1/2 signaling pathway and apoptosis.
Topics: Acyclic Monoterpenes; Animals; Anticarcinogenic Agents; Apoptosis; bcl-2-Associated X Protein; Carcinogenesis; Cyclooxygenase 2; Edema; Female; Inflammation; MAP Kinase Signaling System; Mice; Oxidative Stress; ras Proteins; Skin; Terpenes; Tetradecanoylphorbol Acetate | 2013 |