tetradecanoylphorbol acetate has been researched along with Cancer of Stomach in 63 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (14.29) | 18.7374 |
| 1990's | 24 (38.10) | 18.2507 |
| 2000's | 23 (36.51) | 29.6817 |
| 2010's | 7 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, Y; Liu, X; Lu, Y; Pei, B; Shen, W; Sun, D; Wang, X; Xiu, L; Xu, J; Yue, X; Zhang, X | 1 |
| Xia, C; Zhang, B | 2 |
| Karibasappa, GS; Pakhale, SS; Ramchandani, AG | 1 |
| Fujiki, H; Suganuma, M | 1 |
| Du, B; Han, H; Lian, X; Liu, J; Liu, M; Pan, X; Qian, M; Zhao, Q | 1 |
| Chang, JX; Chen, HB; Du, ZP; Li, EM; Lv, Z; Shen, J; Wu, BL; Wu, JY; Xu, LY; Yuan, HM | 1 |
| Fukayama, M; Fukushima, N; Ishikawa, S; Kokudo, N; Shibahara, J; Shinozaki, A; Tanaka, M; Umeda, M | 1 |
| Chen, N; Chen, W; Cheng, P; Guo, G; Li, N; Liu, T; Liu, X; Mao, X; Peng, L; Shi, Y; Tong, W; Wang, T; Yu, P; Zhang, J; Zhao, Y; Zhuang, Y; Zou, Q | 1 |
| Joo, YE; Jung, YD; Khoi, PN; Lang, SA; Lee, YH; Park, JS; Stoeltzing, O | 1 |
| Ashcroft, FJ; Dockray, GJ; Noble, PJ; Pagliocca, A; Varro, A; Wroblewski, LE | 1 |
| Huang, ZW; Liu, S; Su, WJ; Wu, Q; Ye, XF | 1 |
| Chen, Y; Song, SY; Su, WJ; Wu, Q | 1 |
| Fleming, J; Höcker, M; Raychowdhury, R; Rosewicz, S; Schäfer, G; Wang, TC; Wiedenmann, B | 1 |
| Fan, XM; Jiang, SH; Jiang, Xh; Kung, HF; Lam, SK; Lin, MC; Wong, BC | 1 |
| Lin, XF; Liu, S; Su, WJ; Wu, JF; Wu, Q; Ye, XF; Zhang, B; Zhang, MQ | 1 |
| Jakobsson, PJ; Offerhaus, GJ; Ristimäki, A; Sivula, A; Thorén, S; van Rees, BP; Yokozaki, H | 1 |
| Chen, MC; Lin, XF; Liu, S; Wu, Q; Ye, XF; Zhang, B | 1 |
| Cui, JT; Jiang, SH; Jiang, XH; Kung, HF; Lam, SK; Lin, MC; Tu, SP; Wong, BC; Wong, WM; Yuen, MF | 1 |
| Fukushima, M; Hiyama, K; Nishiyama, M; Noguchi, T; Shimokuni, T; Tanimoto, K; Toge, T; Tsujimoto, H; Ukon, K | 1 |
| Fenger, C; Holmskov, U; Kang, W; Leslie, G; Nielsen, O; Reid, KB | 1 |
| Dixon, DA; Haglund, C; Hallikainen, T; Heinonen, M; Hemmes, A; Rintahaka, J; Ristimäki, A; Thiel, A | 1 |
| Kim, JG; Kim, SH; Kim, YB; Lee, JW; Lee, MS; Lee, SY; Ye, SK | 1 |
| Imaeda, T; Niimi, T; Yano, K | 1 |
| Habs, M; Schmähl, D; Wagner, G | 1 |
| Goerttler, K; Hesse, B; Loehrke, H; Schweizer, J | 2 |
| Hanson, PJ; McKenna, JP; Williams, JM | 1 |
| Ishii, S; Izumi, T; Kato, S; Mutoh, H; Shimizu, T | 1 |
| Comoglio, PM; Gandino, L; Longati, P; Medico, E; Prat, M | 1 |
| Satomi, Y | 1 |
| Gespach, CP; Hanson, PJ; McKenna, P; Williams, JM | 1 |
| Hengels, KJ; Piontek, M; Porschen, R; Strohmeyer, G | 1 |
| Kasuga, M; Konda, Y; Matozaki, S; Matozaki, T; Matsuda, K; Nakano, O; Sakamoto, C; Suzuki, T; Uchida, T; Wada, K | 1 |
| Höcker, M; Koh, TJ; Wang, TC; Zhang, Z | 1 |
| Ali, AM; el-Sharkawy, SH; Hamid, M; Intan-Safinar, I; Lajis, NH; Mackeen, MM; Murakoshi, M | 1 |
| Kikkawa, Y; Misugi, K; Miyagi, Y; Miyazaki, K; Mizushima, H; Yamanaka, N; Yasumitsu, H | 1 |
| de Vries, A; Dortant, PM; Kroese, ED; van der Houven van Oordt, CW; van Kranen, HJ; van Kreijl, CF; van Oostrom, CT; van Steeg, H; Wester, PW | 1 |
| Beales, IL; Calam, J | 1 |
| Henihan, RJ; Höcker, M; Koh, TJ; Riecken, EO; Rosewicz, S; Wang, TC; Zhang, Z | 1 |
| Bhisey, RA; Borges, AM; D'Souza, AV; Ramchandani, AG | 1 |
| Hoshikawa, Y; Katsumoto, T; Kurata, T; Okinaga, K; Sairenji, T; Satoh, Y; Tajima, M; Takasaka, N | 1 |
| Hanai, H; Kajimura, M; Kaneko, E; Kodaira, M; Lin, S; Takeuchi, K | 1 |
| Adachi, M; Hinoda, Y; Imai, K; Miyazawa, M; Okuda, H | 1 |
| Afanasjev, S; Antipov, S; Cherdyntseva, N; Schepetkin, I; Zyryanov, B | 1 |
| Hoshikawa, Y; Kanamori, M; Kurata, T; Miyazawa, Y; Okinaga, K; Sairenji, T; Satoh, Y; Tajima, M | 1 |
| Izawa, M; Teramachi, K | 2 |
| Goerttler, K; Hesse, B; Löhrke, H | 1 |
| Choe, TB; Hong, SI; Jang, JJ; Lee, JI; Lee, SH; Park, IC; Park, MJ; Rhee, CH | 1 |
| Chen, ZM; Su, WJ; Wu, Q | 1 |
| Cai, JH; Huang, ZW; Liu, S; Su, WJ; Wu, Q; Ye, XF | 1 |
| Goldschmidt, BM; Loewengart, G; Melchionne, S; Roth, D; Seldman, I; Smith, AC; Van Duuren, BL | 1 |
| Gespach, C; Hanson, PJ; McKenna, P; Williams, JM | 1 |
| Johnson, AC; Kageyama, R; Pastan, I; Popescu, NC | 1 |
| Briantais, MJ; Brivet, M; Galanaud, P; Khellaf, A; Lebrun, L; Pelletier, G | 1 |
| Borunov, EV; Naumov, SA; Shepetkin, IE; Skutina, IL | 1 |
| Bussolino, F; Comoglio, PM; Di Renzo, MF; Gandino, L; Giordano, S | 1 |
| Kawamoto, S; Oh-uchida, M; Shimizu, K; Yano, K | 1 |
| Abe, K; Ito, H; Ochiai, A; Tahara, E; Yamamoto, T; Yanaihara, N; Yasui, W | 1 |
| Li, MH; Liu, JG | 1 |
| Gamou, S; Hirai, M; Kobayashi, M; Shimizu, N | 1 |
| Han, YL; Lin, ZX; Trosko, JE; Zhang, RF; Zhau, YL | 1 |
1 review(s) available for tetradecanoylphorbol acetate and Cancer of Stomach
| Article | Year |
|---|---|
Carcinogenic aspects of protein phosphatase 1 and 2A inhibitors.
Topics: Animals; Carcinogens; Disease Progression; Enzyme Inhibitors; Humans; Marine Toxins; Mice; Models, Molecular; Neoplasms; Neoplasms, Experimental; Okadaic Acid; Oxazoles; Protein Phosphatase 1; Protein Phosphatase 2; Rats; Skin Neoplasms; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2009 |
1 trial(s) available for tetradecanoylphorbol acetate and Cancer of Stomach
| Article | Year |
|---|---|
The luminol-amplified chemiluminescence of neutrophils and monocytes in patients with gastric cancer after intraoperative radiotherapy using radiosensitizer sanazole.
Topics: Adenocarcinoma; Aged; Female; Humans; Intraoperative Period; Luminescent Measurements; Luminol; Lymphoma, Non-Hodgkin; Male; Middle Aged; Monocytes; Neutrophil Activation; Neutrophils; Radiation-Sensitizing Agents; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Triazoles | 1999 |
61 other study(ies) available for tetradecanoylphorbol acetate and Cancer of Stomach
| Article | Year |
|---|---|
Xiao Tan He Wei Decoction reverses MNNG-induced precancerous lesions of gastric carcinoma in vivo and vitro: Regulation of apoptosis through NF-κB pathway.
Topics: Animals; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Disease Models, Animal; Drugs, Chinese Herbal; Epithelial-Mesenchymal Transition; Humans; Hyperplasia; Methylnitronitrosoguanidine; NF-kappa B; Precancerous Conditions; Rats, Wistar; Stomach Neoplasms; Tetradecanoylphorbol Acetate | 2018 |
12-O-tetradecanoylphorbol-1,3-acetate-induced degradation of protein kinase B via ubiquitin-proteasomal pathway depends on its Ser473 phosphorylation in gastric cancer cells.
Topics: Cell Line, Tumor; HEK293 Cells; Humans; Phosphorylation; Phosphoserine; Proteasome Endopeptidase Complex; Proteolysis; Proto-Oncogene Proteins c-akt; Signal Transduction; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Ubiquitin | 2013 |
Antitumor-promoting effects of polyphenolic extracts from seedless and seeded Indian grapes.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogenicity Tests; Esophageal Neoplasms; Female; Flavonoids; India; Male; Mice; Mice, Inbred Strains; Phenols; Plant Extracts; Polyphenols; Seeds; Skin Neoplasms; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Vitis | 2008 |
The expression of protein kinase B in gastric cancer cell apoptosis induced by 12-O-tetradecanoylphorbol-1, 3-acetate.
Topics: Apoptosis; Cell Cycle; Humans; Phosphorylation; Proto-Oncogene Proteins c-akt; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2009 |
CADPE inhibits PMA-stimulated gastric carcinoma cell invasion and matrix metalloproteinase-9 expression by FAK/MEK/ERK-mediated AP-1 activation.
Topics: Caffeic Acids; Cell Line, Tumor; Cell Movement; Extracellular Signal-Regulated MAP Kinases; Focal Adhesion Protein-Tyrosine Kinases; Humans; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Mitogen-Activated Protein Kinases; Neoplasm Invasiveness; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factor AP-1 | 2010 |
Neutrophil gelatinase-associated lipocalin in gastric carcinoma cells and its induction by TPA are controlled by C/EBPβ.
Topics: Acute-Phase Proteins; Base Sequence; Blotting, Western; Carcinoma; CCAAT-Enhancer-Binding Protein-beta; Chromatin Immunoprecipitation; Electrophoretic Mobility Shift Assay; Genes, Reporter; Humans; Lipocalin-2; Lipocalins; Luciferases; Molecular Sequence Data; Plasmids; Proto-Oncogene Proteins; Response Elements; RNA, Messenger; Signal Transduction; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Tumor Cells, Cultured; Up-Regulation | 2011 |
Claudin-18 is an early-stage marker of pancreatic carcinogenesis.
Topics: Adenocarcinoma, Mucinous; Biomarkers, Tumor; Carcinoma, Pancreatic Ductal; Carcinoma, Papillary; Cell Transformation, Neoplastic; Claudins; Enzyme Inhibitors; Humans; Indoles; Maleimides; Membrane Proteins; Pancreas; Pancreatic Neoplasms; Pancreatitis, Chronic; Protein Kinase C; Retrospective Studies; Stomach Neoplasms; Tetradecanoylphorbol Acetate | 2011 |
Increased circulating Th22 and Th17 cells are associated with tumor progression and patient survival in human gastric cancer.
Topics: Adult; Aged; Case-Control Studies; Cells, Cultured; Female; Flow Cytometry; Humans; Immunity, Innate; Immunophenotyping; Interleukin-17; Interleukin-22; Interleukins; Lymphatic Metastasis; Lymphocyte Activation; Lymphocyte Count; Male; Middle Aged; Neoplasm Staging; Stomach Neoplasms; Survival Analysis; T-Lymphocytes, Helper-Inducer; Tetradecanoylphorbol Acetate; Th17 Cells | 2012 |
EGCG inhibits recepteur d'origine nantais expression by suppressing Egr-1 in gastric cancer cells.
Topics: Animals; Catechin; Cell Line, Tumor; DNA-Binding Proteins; Early Growth Response Protein 1; Enzyme Activation; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Neoplasm Transplantation; Plant Extracts; Promoter Regions, Genetic; Receptor Protein-Tyrosine Kinases; RNA Interference; RNA, Small Interfering; Stomach Neoplasms; Tea; Tetradecanoylphorbol Acetate; Transcription, Genetic; Xenograft Model Antitumor Assays | 2013 |
Stimulation of the gastrin-cholecystokinin(B) receptor promotes branching morphogenesis in gastric AGS cells.
Topics: Basement Membrane; Cell Adhesion; Gastrins; Humans; Lysophospholipids; Protein Kinase C; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2002 |
Dual roles of Nur77 in selective regulation of apoptosis and cell cycle by TPA and ATRA in gastric cancer cells.
Topics: Apoptosis; Cell Cycle; Cycloheximide; DNA-Binding Proteins; Epidermal Growth Factor; Genetic Vectors; Humans; Nuclear Receptor Subfamily 4, Group A, Member 1; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Recombinant Proteins; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factors; Transfection; Tretinoin; Tumor Cells, Cultured | 2002 |
Activation of JNK by TPA promotes apoptosis via PKC pathway in gastric cancer cells.
Topics: Apoptosis; Enzyme Activation; Genes, jun; Humans; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases; Protein Kinase C; RNA, Messenger; RNA, Neoplasm; Signal Transduction; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Tumor Cells, Cultured | 2002 |
Interaction of early growth response protein 1 (Egr-1), specificity protein 1 (Sp1), and cyclic adenosine 3'5'-monophosphate response element binding protein (CREB) at a proximal response element is critical for gastrin-dependent activation of the chromog
Topics: Binding Sites; Cell Nucleus; Chromogranin A; Chromogranins; Cyclic AMP Response Element-Binding Protein; DNA; DNA-Binding Proteins; Early Growth Response Protein 1; Enzyme Inhibitors; Epithelial Cells; Flavonoids; Gastrins; Humans; Immediate-Early Proteins; Immunoblotting; MAP Kinase Kinase 1; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Phosphorylation; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; Response Elements; Signal Transduction; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factors; Transcriptional Activation; Transfection; Tumor Cells, Cultured | 2002 |
Suppression of RelA/p65 nuclear translocation independent of IkappaB-alpha degradation by cyclooxygenase-2 inhibitor in gastric cancer.
Topics: Active Transport, Cell Nucleus; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Aspirin; Colonic Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; DNA, Neoplasm; Enzyme Activation; Humans; I-kappa B Kinase; I-kappa B Proteins; Isoenzymes; Membrane Proteins; Neoplasm Proteins; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; Prostaglandin-Endoperoxide Synthases; Protein Binding; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Pyrazoles; Stomach Neoplasms; Sulfonamides; Tetradecanoylphorbol Acetate; Transcription Factor RelA; Transcription, Genetic; Transfection; Tumor Necrosis Factor-alpha | 2003 |
Degradation of retinoid X receptor alpha by TPA through proteasome pathway in gastric cancer cells.
Topics: Carcinogens; Cysteine Endopeptidases; Humans; Multienzyme Complexes; Proteasome Endopeptidase Complex; Receptors, Retinoic Acid; Retinoid X Receptors; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factors; Tumor Cells, Cultured | 2003 |
Expression of microsomal prostaglandin E synthase-1 in intestinal type gastric adenocarcinoma and in gastric cancer cell lines.
Topics: Adenocarcinoma; Blotting, Northern; Blotting, Western; Carcinogens; Cyclooxygenase 2; Dinoprostone; Enzyme Induction; Gastric Mucosa; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Immunoenzyme Techniques; Interleukin-1; Intestines; Intramolecular Oxidoreductases; Isoenzymes; Lung Neoplasms; Membrane Proteins; Microsomes; Prostaglandin-E Synthases; Prostaglandin-Endoperoxide Synthases; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2003 |
Roles of PLC-gamma2 and PKCalpha in TPA-induced apoptosis of gastric cancer cells.
Topics: Apoptosis; Carcinogens; Cell Line, Tumor; Humans; Phospholipase C gamma; Protein Kinase C; Protein Kinase C-alpha; Signal Transduction; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Type C Phospholipases | 2003 |
Cyclooxygenase-2 inhibitor (SC-236) suppresses activator protein-1 through c-Jun NH2-terminal kinase.
Topics: Cell Division; Cell Line, Tumor; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Activation; Humans; Isoenzymes; JNK Mitogen-Activated Protein Kinases; Membrane Proteins; Mitogen-Activated Protein Kinases; Phosphorylation; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Stomach Neoplasms; Sulfonamides; Tetradecanoylphorbol Acetate; Transcription Factor AP-1 | 2004 |
Activator protein accelerates dihydropyrimidine dehydrogenase gene transcription in cancer cells.
Topics: Binding Sites; Biomarkers, Tumor; Cell Line, Transformed; Cell Line, Tumor; Dihydrouracil Dehydrogenase (NADP); Humans; Ionomycin; Kidney; Promoter Regions, Genetic; RNA, Messenger; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription, Genetic; Transcriptional Activation; Transfection | 2005 |
Induction of DMBT1 expression by reduced ERK activity during a gastric mucosa differentiation-like process and its association with human gastric cancer.
Topics: Adenocarcinoma; Agglutinins; Calcium-Binding Proteins; Cell Cycle Proteins; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cyclin D3; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA-Binding Proteins; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Gastric Mucosa; Gene Expression Regulation, Neoplastic; Humans; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Organ Specificity; Protein Kinase C; Proteins; Receptors, Cell Surface; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factors; Trefoil Factor-1; Tumor Suppressor Proteins | 2005 |
Expression of cyclooxygenase-2 is regulated by glycogen synthase kinase-3beta in gastric cancer cells.
Topics: Aminophenols; Blotting, Northern; Blotting, Western; Cell Line, Tumor; Chromones; Cyclooxygenase 2; Dinoprostone; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Genes, Reporter; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Indoles; Lithium Chloride; Maleimides; Models, Biological; Models, Statistical; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; Signal Transduction; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Transfection | 2006 |
Integrin signaling and cell spreading mediated by phorbol 12-myristate 13-acetate treatment.
Topics: Carcinoma; Cell Line, Tumor; Cell Movement; Cofilin 1; CSK Tyrosine-Protein Kinase; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fibronectins; Focal Adhesion Kinase 1; Humans; Integrins; Molecular Mimicry; Paxillin; Phosphorylation; Protein Kinase C-delta; Protein-Tyrosine Kinases; rhoA GTP-Binding Protein; src-Family Kinases; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2006 |
Transcriptional activation of the human claudin-18 gene promoter through two AP-1 motifs in PMA-stimulated MKN45 gastric cancer cells.
Topics: 5' Flanking Region; Base Sequence; Carcinogens; Cell Line, Tumor; Claudins; Gene Expression Regulation, Neoplastic; Genes, Reporter; Humans; Membrane Proteins; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Mutation; Promoter Regions, Genetic; Protein Kinase C; Protein Kinase Inhibitors; RNA, Messenger; Signal Transduction; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription, Genetic; Transcriptional Activation; Up-Regulation; Vimentin | 2008 |
Inhibition of the promotion phase in two-step carcinogenesis in forestomach epithelium of mice by the aromatic retinoid etretinate.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Carcinogens; Epithelium; Etretinate; Female; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin | 1983 |
Positive two-stage carcinogenesis in female Sprague-Dawley rats using 7,12-dimethylbenz(a)anthracene (dmba) as initiator and 12-o-tetradecanoylphorbol-13-acetate (tps) as promotor. Results of a pilot study.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Benz(a)Anthracenes; Castration; Cocarcinogenesis; Colonic Neoplasms; Female; Intestinal Neoplasms; Liver Neoplasms; Phorbols; Rats; Skin Neoplasms; Stomach; Stomach Neoplasms; Tetradecanoylphorbol Acetate | 1980 |
The alpha isoform of protein kinase C inhibits histamine-stimulated adenylate cyclase activity in a particulate fraction of the human gastric cancer cell line HGT-1.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Amino Acid Sequence; Calcium; Cell Fractionation; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Histamine; Humans; Immunoblotting; Isoenzymes; Molecular Sequence Data; Myelin Basic Protein; Phosphorylation; Protein Kinase C; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Platelet-activating factor (PAF) positively auto-regulates the expression of human PAF receptor transcript 1 (leukocyte-type) through NF-kappa B.
Topics: Base Sequence; Cell Line; Chloramphenicol O-Acetyltransferase; DNA Primers; Gene Expression Regulation, Neoplastic; Humans; Leukocytes; Molecular Sequence Data; NF-kappa B; Open Reading Frames; Platelet Activating Factor; Platelet Membrane Glycoproteins; Promoter Regions, Genetic; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Tumor Cells, Cultured; Up-Regulation | 1994 |
Phosphorylation of serine 985 negatively regulates the hepatocyte growth factor receptor kinase.
Topics: Amino Acid Sequence; Calcimycin; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Consensus Sequence; Hepatocyte Growth Factor; Humans; Kinetics; Molecular Sequence Data; Peptide Fragments; Phosphates; Phosphopeptides; Phosphorylation; Protein Kinase C; Proto-Oncogene Proteins c-met; Proto-Oncogenes; Receptor Protein-Tyrosine Kinases; Sequence Homology, Amino Acid; Serine; Stomach Neoplasms; Substrate Specificity; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Inhibitory effects of 3'-methyl-3-hydroxy-chalcone on proliferation of human malignant tumor cells and on skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Division; Chalcone; Chalcones; Dose-Response Relationship, Drug; HeLa Cells; Humans; Mice; Neoplasm Proteins; Neoplasms; Papilloma; Phosphorylation; Skin Neoplasms; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured | 1993 |
Protein kinase C inhibits cyclic adenosine monophosphate generation by histamine and truncated glucagon like peptide 1 in the human gastric cancer cell line HGT-1.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Alkaloids; Cyclic AMP; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Histamine; Humans; Peptide Fragments; Pertussis Toxin; Protein Kinase C; Protein Precursors; Receptors, Gastrointestinal Hormone; Receptors, Histamine H2; Staurosporine; Stimulation, Chemical; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1993 |
Protein kinase C and adenylate cyclase as targets for growth inhibition of human gastric cancer cells.
Topics: Adenocarcinoma; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Alkaloids; Bucladesine; Cell Division; Colforsin; Enzyme Activation; Humans; Protein Kinase C; Staurosporine; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Phorbol ester stimulates the activity of a protein tyrosine phosphatase containing SH2 domains (PTP1C) in HL-60 leukemia cells by increasing gene expression.
Topics: Base Sequence; Cycloheximide; DNA, Neoplasm; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Genes, src; Humans; Immunoblotting; Isoenzymes; Kinetics; Leukemia, Promyelocytic, Acute; Molecular Sequence Data; Oligodeoxyribonucleotides; Protein Tyrosine Phosphatases; RNA, Messenger; Sequence Homology, Nucleic Acid; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Transcription, Genetic; Tumor Cells, Cultured | 1993 |
The human histidine decarboxylase promoter is regulated by gastrin and phorbol 12-myristate 13-acetate through a downstream cis-acting element.
Topics: Base Sequence; Cell Line; Cell Nucleus; Cloning, Molecular; DNA Primers; Female; Gastrins; Gene Expression Regulation, Enzymologic; Genomic Library; HeLa Cells; Histidine Decarboxylase; Humans; Kinetics; Luciferases; Molecular Sequence Data; Placenta; Polymerase Chain Reaction; Pregnancy; Promoter Regions, Genetic; Protein Kinase C; Recombinant Proteins; Regulatory Sequences, Nucleic Acid; Sequence Deletion; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transcriptional Activation; Transfection; Tumor Cells, Cultured | 1996 |
Antitumour-promoting and antitumour activities of the crude extract from the leaves of Juniperus chinensis.
Topics: Administration, Topical; Animals; Anticarcinogenic Agents; Antineoplastic Agents; Carcinoma; Cell Division; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Female; HeLa Cells; Humans; Juniperus; Malaysia; Mice; Plant Extracts; Plant Leaves; Skin Neoplasms; Specific Pathogen-Free Organisms; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1996 |
Differential expression of laminin-5/ladsin subunits in human tissues and cancer cell lines and their induction by tumor promoter and growth factors.
Topics: Blotting, Northern; Cell Adhesion; Cell Adhesion Molecules; Epidermal Growth Factor; Gene Expression Regulation, Neoplastic; Humans; Kalinin; Molecular Sequence Data; Platelet-Derived Growth Factor; Protein Conformation; RNA, Messenger; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta; Tumor Cells, Cultured; Up-Regulation | 1996 |
Use of E mu-PIM-1 transgenic mice short-term in vivo carcinogenicity testing: lymphoma induction by benzo[a]pyrene, but not by TPA.
Topics: Animals; Benzo(a)pyrene; Body Weight; Carcinogens; Enhancer Elements, Genetic; Female; Gene Expression Regulation, Neoplastic; Genes, myc; Immunoglobulin mu-Chains; Lymphoma; Male; Mice; Mice, Transgenic; Neoplasms, Experimental; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-pim-1; Stomach Neoplasms; Tetradecanoylphorbol Acetate | 1997 |
Helicobacter pylori stimulates granulocyte-macrophage colony-stimulating factor (GM-CSF) production from cultured antral biopsies and a human gastric epithelial cell line.
Topics: Adenocarcinoma; Bacteriological Techniques; Biopsy; Carcinogens; Chronic Disease; Enzyme-Linked Immunosorbent Assay; Epithelium; Gastric Mucosa; Gastroscopy; Granulocyte-Macrophage Colony-Stimulating Factor; Helicobacter Infections; Helicobacter pylori; Humans; Pyloric Antrum; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1997 |
Gastrin and phorbol 12-myristate 13-acetate regulate the human histidine decarboxylase promoter through Raf-dependent activation of extracellular signal-regulated kinase-related signaling pathways in gastric cancer cells.
Topics: Base Sequence; Calcium-Calmodulin-Dependent Protein Kinases; Gastrins; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Genes, Reporter; Histidine Decarboxylase; Humans; JNK Mitogen-Activated Protein Kinases; Luciferases; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Myelin Basic Protein; Phosphorylation; Promoter Regions, Genetic; Recombinant Fusion Proteins; Signal Transduction; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Transfection | 1997 |
Evaluation of carcinogenic/co-carcinogenic activity of a common chewing product, pan masala, in mouse skin, stomach and esophagus.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Areca; Cocarcinogenesis; Esophageal Neoplasms; Female; Male; Mice; Mice, Hairless; Mice, Inbred ICR; Plants, Medicinal; Powders; Skin Neoplasms; Stomach Neoplasms; Tetradecanoylphorbol Acetate | 1998 |
Productive infection of Epstein-Barr virus (EBV) in EBV-genome-positive epithelial cell lines (GT38 and GT39) derived from gastric tissues.
Topics: Animals; Butyrates; Butyric Acid; Cell Line; DNA-Binding Proteins; Epithelial Cells; Epstein-Barr Virus Nuclear Antigens; Fluorescent Antibody Technique; Genotype; Herpesviridae Infections; Herpesvirus 4, Human; Humans; Stomach; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Trans-Activators; Tumor Virus Infections; Viral Proteins; Virus Replication | 1998 |
Functional muscarinic m3 receptor expressed in gastric cancer cells stimulates tyrosine phosphorylation and MAP kinase.
Topics: Atropine; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Carbachol; Densitometry; Dose-Response Relationship, Drug; Humans; Intracellular Fluid; Naphthalenes; Phosphorylation; Receptor, Muscarinic M3; Receptors, Muscarinic; Reverse Transcriptase Polymerase Chain Reaction; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha; Tumor Cells, Cultured; Tyrosine | 1999 |
Protein kinase Calpha promotes apoptotic cell death in gastric cancer cells depending upon loss of anchorage.
Topics: Adenocarcinoma; Apoptosis; Caspase 3; Caspases; Cell Adhesion; Enzyme Activation; Humans; Isoenzymes; MAP Kinase Signaling System; Neoplasm Proteins; Protein Kinase C; Protein Kinase C-alpha; Recombinant Fusion Proteins; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1999 |
Differential effect of TPA on cell growth and Epstein-Barr virus reactivation in epithelial cell lines derived from gastric tissues and B cell line Raji.
Topics: Blotting, Western; Burkitt Lymphoma; Cell Cycle; Cell Division; Cell Survival; Culture Media; Epithelial Cells; Flow Cytometry; Herpesvirus 4, Human; Humans; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Virus Activation | 2000 |
Rapid induction of apoptosis in human gastric cancer cell lines by sorbitol.
Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Cysteine Proteinase Inhibitors; DNA Fragmentation; Humans; Sorbitol; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2000 |
Two-stage carcinogenesis in NMRI mice: intravaginal application of 7,12-dimethylbenz[a]anthracene as initiator followed by the phorbol ester 12-O-tetradecanoylphorbol-13-acetate as promoter.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenoma; Administration, Intravaginal; Animals; Carcinogens; Carcinoma; Cocarcinogenesis; Drug Synergism; Female; Hyperplasia; Leukemia, Experimental; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Models, Animal; Neoplasms, Experimental; Organ Specificity; Ovarian Neoplasms; Papilloma; Precancerous Conditions; Sarcoma, Experimental; Specific Pathogen-Free Organisms; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Vagina; Vaginal Neoplasms | 1980 |
Protein kinase C activation by PMA rapidly induces apoptosis through caspase-3/CPP32 and serine protease(s) in a gastric cancer cell line.
Topics: Adenocarcinoma; Apoptosis; Blotting, Western; Caspase 3; Caspases; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Humans; Neoplasm Proteins; Serine Endopeptidases; Serine Proteinase Inhibitors; Stomach Neoplasms; Sulfones; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2001 |
Down-regulation of protein kinase C activity by sorbitol rapidly induces apoptosis in human gastric cancer cell lines.
Topics: Apoptosis; Cycloheximide; Down-Regulation; Enzyme Inhibitors; Fibroblasts; HeLa Cells; Humans; Indoles; Kinetics; Maleimides; Protein Kinase C; Sorbitol; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2001 |
Anticancer effect of retinoic acid via AP-1 activity repression is mediated by retinoic acid receptor alpha and beta in gastric cancer cells.
Topics: Antineoplastic Agents; Cell Division; DNA-Binding Proteins; Genes, Reporter; Humans; Protein Binding; Protein Structure, Tertiary; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Tretinoin; Tumor Cells, Cultured | 2002 |
Induction of apoptosis by TPA and VP-16 is through translocation of TR3.
Topics: Active Transport, Cell Nucleus; Apoptosis; DNA-Binding Proteins; Etoposide; Gene Expression; Nuclear Receptor Subfamily 4, Group A, Member 1; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; RNA, Messenger; RNA, Neoplasm; Signal Transduction; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factors; Tumor Cells, Cultured | 2002 |
Systemic two-stage carcinogenesis in the epithelium of the forestomach of mice using 7,12-dimethylbenz(a)anthracene as initiator and the phorbol ester 12-O-tetradecanoylphorbol-13-acetate as promoter.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Cocarcinogenesis; Drug Synergism; Epithelium; Female; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Phorbols; Stomach Neoplasms; Tetradecanoylphorbol Acetate | 1979 |
Carcinogenicity of halogenated olefinic and aliphatic hydrocarbons in mice.
Topics: Animals; Carcinogens, Environmental; Cocarcinogenesis; Drug Evaluation, Preclinical; Female; Hydrocarbons, Halogenated; Lung Neoplasms; Male; Mice; Neoplasms, Experimental; Papilloma; Sarcoma, Experimental; Skin Neoplasms; Stomach Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1979 |
Protein kinase C inhibits histamine H2 receptor-mediated stimulation of cyclic AMP content in the human gastric cancer cell line HGT-1.
Topics: Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; Histamine; Histamine H2 Antagonists; Humans; Protein Kinase C; Receptors, Histamine H2; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
Expression and chromosomal localization of the gene for the human transcriptional repressor GCF.
Topics: Animals; Blotting, Northern; Chromosome Banding; Chromosome Mapping; Chromosomes, Human, Pair 1; Clone Cells; Humans; Karyotyping; KB Cells; Melanoma; Plasmacytoma; Repressor Proteins; Restriction Mapping; RNA; RNA Probes; RNA, Messenger; RNA, Neoplasm; Stomach Neoplasms; Tetradecanoylphorbol Acetate | 1992 |
Enhancement of normal polymorphonuclear cells respiratory burst in ascitic fluid by fibronectin. Comparison between cirrhotic and malignant ascitic fluids.
Topics: Adult; Aged; Aged, 80 and over; Ascitic Fluid; Bacterial Infections; Disease Susceptibility; Dose-Response Relationship, Drug; Female; Fibronectins; Humans; Liver Cirrhosis; Luminescent Measurements; Middle Aged; Neutrophils; Ovarian Neoplasms; Peritonitis; Respiratory Burst; Risk Factors; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Zymosan | 1992 |
[The activation of the early chemiluminescent response of human neutrophils by joint treatment with tumor necrosis factor (TNF-alpha) and the calcium ionophore A-23187].
Topics: Acridines; Calcimycin; Cells, Cultured; Humans; Luminescent Measurements; Luminol; Neutrophils; Oxygen; Precancerous Conditions; Recombinant Proteins; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Tumor Necrosis Factor-alpha | 1991 |
Protein kinase-c activation inhibits tyrosine phosphorylation of the c-met protein.
Topics: Animals; Diglycerides; Gene Amplification; Gene Expression; Humans; Phorbol Esters; Phosphorylation; Precipitin Tests; Protein Kinase C; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-met; Serine; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine | 1990 |
Transformation-specific decrease of phosphorylation of 80K protein, a substrate of protein kinase C, in NIH3T3 cells.
Topics: Cell Line, Transformed; Enzyme Activation; Humans; Molecular Weight; Phosphorylation; Protein Kinase C; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Stomach Neoplasms; Substrate Specificity; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Immunohistochemical detection of c-myc oncogene product in human gastric carcinomas: expression in tumor cells and stromal cells.
Topics: Epidermal Growth Factor; Humans; Immunohistochemistry; Interferons; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myc; Stomach; Stomach Neoplasms; Tetradecanoylphorbol Acetate | 1987 |
Roussin red methyl ester, a tumor promoter isolated from pickled vegetables.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Esophageal Neoplasms; Nitroso Compounds; Ornithine Decarboxylase; Rats; Rats, Inbred Strains; Skin Neoplasms; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Vegetables | 1989 |
Lung cancer cells often express high levels of protein kinase C activity.
Topics: Animals; Calcium; Chromatography; Female; Humans; Lung Neoplasms; Mice; Pancreatic Neoplasms; Phosphatidylserines; Protein Kinase C; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Tongue Neoplasms; Tumor Cells, Cultured; Vulvar Neoplasms | 1989 |
[Studies on the gap junctional intercellular communication (GJIC) of human stomach carcinoma cells in comparison with normal cells and the effect of the tumor promoter, TPA].
Topics: Adenocarcinoma; Animals; Cell Communication; Cells, Cultured; Chick Embryo; Cricetinae; Humans; Intercellular Junctions; Rats; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Trifluoperazine; Tumor Cells, Cultured | 1989 |