tetradecanoylphorbol acetate has been researched along with Cancer of Lung in 172 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 40 (23.26) | 18.7374 |
| 1990's | 70 (40.70) | 18.2507 |
| 2000's | 39 (22.67) | 29.6817 |
| 2010's | 20 (11.63) | 24.3611 |
| 2020's | 3 (1.74) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, S; Gong, M; Han, H; Liu, Y; Ma, J; Song, Y | 1 |
| Arpinati, L; Fridlender, ZG; Kaisar-Iluz, N; Mahroum, S; Mali, S; Shaul, ME | 1 |
| Chauhan, SJ; Chen, Y; Sahu, RP; Thyagarajan, A; Travers, JB | 1 |
| Dastmalchi, S; Hasanifard, L; Karimi, P; Rashtchizadeh, N; Samadi, N | 1 |
| Chen, Y; Keng, PC; Lee, SO; Shen, M; Tsai, Y; Xu, L; Xue, X; Zhu, R | 1 |
| Chao, TY; Chen, TC; Chou, HL; Chu, CM; Hsieh, CH; Lin, LI; Yao, CT | 1 |
| Lavinskiene, S; Miliauskas, S; Sakalauskas, R; Vaguliene, N; Zemaitis, M | 1 |
| Im, M; Jung, YP; Kim, A; Kim, T; Ma, JY; Yim, NH | 1 |
| Im, M; Jung, YP; Kim, A; Ma, JY; Yim, NH | 1 |
| Chang, JE; Jin, QR; Lee, WJ; Maeng, HJ; Shim, WS | 1 |
| Bouvard, C; Bussolino, F; Chiaverina, G; di Blasio, L; Gagliardi, PA; Helley, D; Jain, RK; Primo, L; Puliafito, A; Seano, G; Serini, G; Sessa, R; Sorokin, L; Tarone, G | 1 |
| Cao, LL; Deng, D; Du, Y; He, Q; Hou, T; Li, M; Lu, S; Shen, C; Wang, H; Wang, L; Yang, Y; Zhao, Y; Zhu, WG | 1 |
| Ghosh, A; Ghosh, S; Krishna, M | 1 |
| Im, M; Kim, A; Ma, JY | 1 |
| Azzarone, B; Caignard, A; Charpentier, B; Chouaib, S; Devocelle, A; Eid, P; Fabbi, M; Ferrini, S; Giron-Michel, J; Giuliani, M; Gu, Y; Khawam, K; Ludwig, A; Perier, A | 1 |
| Kadara, H; Lacroix, L; Lotan, D; Lotan, R; Tahara, E | 1 |
| Badmaev, V; Chen, WJ; Chiou, YS; Ho, CT; Pan, MH; Wang, JM | 1 |
| Chang, WT; Chao, CH; Chiang, TA; Huang, GY; Lee, YC; Shieh, JM; Shih, YW; Shih, YX | 1 |
| Kalinovsky, T; Monterrey, JC; Niedzwiecki, A; Rath, M; Roomi, MW | 1 |
| Choi, CY; Choi, JH; Choi, JM; Chung, YC; Han, EH; Hwang, YP; Jeong, HG; Seo, JK | 1 |
| Chen, PS; Chien, ST; Lee, JH; Shih, YW; Wu, SH; Yin, LT | 1 |
| Brautigan, DL; Chandra, N; Conaway, MR; Owens, C; Theodorescu, D; Wang, H | 1 |
| Chen, Z; Jin, H; Lei, Y; Luo, H; Su, C; Wang, T; Zhong, B; Zhuang, M; Zou, J | 1 |
| Jang, SW; Kang, H; Kim, Y; Kim, YS; Ko, J; Sull, JW; Sung, HJ | 1 |
| Li, J; Li, L; Qiang, M; Sun, S; Tang, B; Xu, K | 1 |
| Chen, C; Huang, Y; Li, Y; Ruan, Z; Zhang, D | 1 |
| Chen, YL; Hsu, CL; Sun, FM; Tsai, CM; Weng, CJ; Yen, GC | 1 |
| Wolf, G | 1 |
| Batra, RK; Dohadwala, M; Dubinett, SM; Lin, Y; Luo, J; Pold, M; Sharma, S | 1 |
| Chow, KC; Fang, HY; Lin, JP; Lin, TS; Wang, LS; Wu, YC | 1 |
| Diwan, BA; Waalkes, MP; Ward, JM | 1 |
| Jakobsson, PJ; Offerhaus, GJ; Ristimäki, A; Sivula, A; Thorén, S; van Rees, BP; Yokozaki, H | 1 |
| Cao, C; Choy, H; Freeman, ML; Morrow, JD; Saha, D; Sekhar, KR | 1 |
| Chang, HC; Hung, WC | 1 |
| Ding, L; Lang, W; Wang, H; Xiao, L | 1 |
| Beinke, C; Cordes, N | 1 |
| Aggarwal, BB; Koul, D; Shishodia, S | 1 |
| Chen, JJ; Huang, YC; Liao, WY; Lin, YC; Wang, CH; Wang, SS; Yang, PC; Yao, PL | 1 |
| Adiseshaiah, P; Kalvakolanu, DV; Peddakama, S; Reddy, SP; Zhang, Q | 1 |
| Cichy, J; Kulig, P; Puré, E | 1 |
| Chung, FL; Conaway, CC; Halicka, HD; Jhanwar-Uniyal, M; Schwartz, J; Traganos, F; Yang, YM | 1 |
| Bandobashi, K; Kobayashi, M; Kubota, T; Nakata, H; Saito, T; Taguchi, H; Uemura, Y | 1 |
| Baj-Krzyworzeka, M; Baran, J; Brański, P; Ratajczak, MZ; Szatanek, R; Urbanowicz, B; Weglarczyk, K; Zembala, M | 1 |
| Blumberg, PM; Choi, SH; Hyman, T | 1 |
| Combes, A; Gougat, C; Henriquet, C; Lazennec, G; Mathieu, M | 1 |
| Duong, HQ; Han, SI; Joo, YM; Kang, HS; Kim, CH; Kim, YJ; Lee, SY; Lim, SC; Moon, JY; Park, HG; Park, MJ; Yoo, MA; Youk, HS | 1 |
| Ballington, JR; Bowman, L; Ding, M; Feng, R; Lu, Y; Wang, SY | 1 |
| Garcia, BH; Hargrave, A; Hommema, E; Kilmer, G; Morgan, A; Nahrahari, J; Webb, B; Wiese, R | 1 |
| Chang, KY; Chang, WC; Chen, BK; Hung, LY; Su, WC; Tseng, JT; Tsou, JH; Wang, WC | 1 |
| Chen, LG; Hung, LY; Li, YZ; Liu, YW; Pan, YS; Tsai, KW; Tsai, YD | 1 |
| Adolf, GR | 1 |
| Kriegel, H; Schmahl, W; Senft, E | 1 |
| Benfield, JR; Cohen, AH; Fu, PC; Hammond, WG; Jensen, T; Pak, HY; Paladugu, RR; Shors, EC; Teplitz, RL | 1 |
| Bernal, SD; Chen, LB | 1 |
| Lesca, P | 1 |
| Harris, CC; Lechner, JF; Moser, CE; Willey, JC | 1 |
| Doherty, DG; Witschi, HR | 1 |
| Bardócz, S; Ember, I; Karsai, T; Kertai, P; Rády, P | 1 |
| Altman, LC; Ayars, GH; Doyle, T; Rosen, H | 1 |
| Greening, AP; Lowrie, DB | 1 |
| Boorman, GA; Dean, JH; Lauer, LD; Leubke, RW; Luster, MI | 1 |
| Buening, MK; Chang, RL; Conney, AH; Jerina, DM; Lehr, RE; Levin, W; Taylor, CW; Wood, AW; Yagi, H | 1 |
| Aubert, ML; Bonjour, JP; Rizzoli, R; Sappino, AP | 1 |
| Bierke, P; Ehrenberg, L; Granath, F; Rönnbäck, C; Segerbäck, D | 1 |
| Bergh, J; Heldin, P; Teder, P | 1 |
| DaCosta, C; Emura, M | 1 |
| Birrer, M; Chung, P; Draoui, M; Jakowlew, S; Moody, TW; Park, M | 1 |
| Maneckjee, R; Minna, JD | 1 |
| Fujinaka, Y; Saito, S; Yokogoshi, Y; Zhang, CY | 1 |
| Bitonti, AJ; Dumont, JA | 1 |
| Elkind, MM | 1 |
| Chen, ZH; Gopalakrishna, R; Gundimeda, U | 1 |
| Broxterman, HJ; Eekman, CA; Kuiper, CM; Lankelma, J; Pinedo, HM; Schuurhuis, GJ; Versantvoort, CH | 1 |
| Bradshaw, TD; Gescher, A; Pettit, GR; Stanwell, C | 1 |
| Konoshima, T; Kozuka, M; Takasaki, M; Tokuda, H | 1 |
| Battey, J; Draoui, M; Fathi, Z; Moody, TW | 1 |
| Demura, H; Dobashi, I; Horiba, N; Ohmori, N; Suda, T; Tozawa, F; Yamada, M; Yamakado, M | 1 |
| Inada, A; Iwashima, A; Konoshima, T; Kozuka, M; Nakanishi, T; Nishino, H; Tokuda, H | 1 |
| Giaccia, AJ; Hahn, GM; Koong, AC; Saad, AH | 1 |
| Anderson, LM; Diwan, BA; Rehm, S; Rice, JM | 1 |
| Kapadia, GJ; Konoshima, T; Nishino, H; Tokuda, H | 1 |
| Clark, OH; Duh, QY; Herfarth, C; Hoelting, T | 1 |
| Davidson, A; Gozes, I; Moody, TW | 1 |
| Abe, M; Domae, M; Furukawa, T; Hara, N; Kudo, I; Kuwata, H; Matsuki, H; Mitsuyama, T; Nakanishi, Y | 1 |
| Imajoh-Ohmi, S; Kanegasaki, S; Takaku, F; Yagisawa, M; Yazaki, Y; Yonemaru, M; Yuo, A | 1 |
| Hall, TD; Jayaram, HN; Natarajan, V; Pottratz, ST; Scribner, WM | 1 |
| Havemann, K; Heidtmann, HH; Jäger, R; Risse-Hackl, G; Salge, U; Schuermann, M | 1 |
| Janik, P; Miłoszewska, J; Szaniawska, B; Woynarowska, B | 1 |
| Chen, X; Fu, Z; Han, R; Li, Y | 1 |
| Abrahamson, M; Bencina, M; Heidtmann, HH; Kastelic, L; Kopitar-Jerala, N; Lah, TT; Salge, U; Turk, V | 1 |
| Hamano, T; Konoshima, T; Takasaki, M; Tokuda, H; Yasuda, I | 1 |
| Jakowlew, SB; Mariano, JM; You, L | 1 |
| Kuijpers, HJ; Ramaekers, FC; Reutelingsperger, CP; Schutte, B; van Engeland, M | 1 |
| Jakowlew, SB; You, L | 1 |
| Bernhard, EJ; Hua, J; Muschel, RJ; Sehgal, G; Sehgal, I; Thompson, TC | 1 |
| de Coupade, C; Flower, RJ; Parente, L; Russo-Marie, F; Solito, E | 1 |
| Afrakhte, M; Heldin, CH; Heldin, NE; Itoh, S; Jossan, S; Morén, A; Sampath, K; ten Dijke, P; Westermark, B | 1 |
| Haley, KJ; Lilly, CM; Luster, AD; Nakamura, H; Nakamura, T | 1 |
| Quigley, RL; Shafer, SH; Williams, CL | 1 |
| Dunsmore, SE; Matrisian, LM; Parks, WC; Roby, JD; Saarialho-Kere, UK; Welgus, HG; Wilson, CL | 1 |
| Axelson, H; Johansson, I; Larsson, C; Ljungberg, J; Ortoft, E; Påhlman, S; Söderholm, H | 1 |
| Comolli, R; La Porta, CA | 2 |
| Biswal, SS; Bratta, J; Corrigan, LL; Horton, ND; Kehrer, JP | 1 |
| Borchers, MT; Carty, MP; Leikauf, GD | 1 |
| Carlson, DM; Tesfaigzi, J | 1 |
| Konoshima, T; Nishino, H; Takasaki, M; Tokuda, H | 1 |
| Agadir, A; Bost, F; Chen, Gq; Li, Y; Mercola, D; Zhang, X | 1 |
| Braun, DP; Faber, LP; Ortegel, JW; Staren, ED; Warren, WH | 1 |
| Gazdar, AF; Sachdev, GP; Sarkar, MG; Sharma, PM; Virmani, AK | 1 |
| Komatsu, K; Konoshima, T; Nishino, H; Takasaki, M; Tokuda, H | 1 |
| Arber, N; Imoto, M; Kawatani, M; Osada, H; Simizu, S; Takada, M | 1 |
| Chang, RL; Conney, AH; Jerina, DM; Kumar, S; Lehr, RE; Shirai, N; Wood, AW | 1 |
| Matsumori, A; Nunokawa, Y; Sasayama, S | 1 |
| Courtoy, PJ; Giffroy, D; Vaerman, JP | 1 |
| Goerttler, K; Hesse, B; Löhrke, H | 1 |
| Kalvakolanu, DV; Liaw, YS; Patterson, T; Reddy, SP; Vuong, H; Wu, R | 1 |
| Adiseshaiah, P; Kalvakolanu, DV; Patterson, T; Reddy, SP; Shapiro, P; Vuong, H | 1 |
| Covelli, V; Dragani, TA; Galbiati, F; Mancuso, MT; Manenti, G; Pazzaglia, S; Peissel, B; Rebessi, S; Saran, A; Spinola, M; Zaffaroni, D; Zanesi, N | 1 |
| Bousquet, J; Demoly, P; Gagliardo, R; Gougat, C; Henriquet, C; Jaffuel, D; Mathieu, M | 1 |
| Ashlock, M; Esmail, M; Mogayzel, PJ; Wagner, TL; Zeitlin, PL | 1 |
| Goldschmidt, BM; Loewengart, G; Melchionne, S; Roth, D; Seldman, I; Smith, AC; Van Duuren, BL | 1 |
| Sivak, A | 1 |
| Buening, MK; Chang, RL; Conney, AH; Jerina, DM; Karle, JM; Levin, W; Wood, AW; Yagi, H | 1 |
| Buening, MK; Chang, RL; Conney, AH; Jerina, DM; Levin, W; Thakker, DR; Wood, AW | 1 |
| Iwashima, A; Kokumai, M; Konoshima, T; Kozuka, M; Nishino, H; Tokuda, H | 1 |
| Baxter, G; Daniel-Issakani, S; Oto, E; Strulovici, B | 1 |
| Heidtmann, HH; Moldenhauer, G; Schirrmacher, V; Schwartz-Albiez, R; Wolf, D | 1 |
| Fujiki, H; Fujiwara, Y; Kasahara, K; Nishio, K; Nishiwaki, S; Ohata, M; Saijo, N; Sugimoto, Y | 1 |
| Caamano, J; Garcia-Palazzo, I; Harris, CC; Iizasa, T; Klein-Szanto, AJ; Metcalf, R; Momiki, S; Welsh, J | 1 |
| Collins, CL; Cook, CD; Fink, L; Granger, J; Hsu, PL; Hsu, SM; Ordonez, NG; Schaefer, R; Xie, SS | 1 |
| Anderson, L; Langdon, SP; Miller, WR; Rabiasz, GJ; Ritchie, AA; Smyth, JF | 1 |
| Hasegawa, T; Iwashima, A; Kitano, H; Murakoshi, M; Nishino, H; Okabe, H; Okuzumi, J; Satomi, Y; Takayasu, J; Tokuda, H | 1 |
| Bartlett, JM; Crew, AJ; Langdon, SP; Miller, EP; Miller, WR; Rabiasz, GJ; Scott, WN; Smyth, JF | 1 |
| Bradshaw, TD; Gescher, A; Pettit, GR | 2 |
| Clark, JC; Pryhuber, GS; Whitsett, JA; Wispé, JR | 1 |
| Bagash, JM; Coogan, M; Lozano, Y; Young, ME; Young, MR | 1 |
| Aldaz, CM; Chiba, M; Conti, CJ; Klein-Szanto, AJ | 1 |
| Burbach, JP; Sutanto, W; Verbeeck, MA | 1 |
| Loktionov, A; Martel, N; Popovich, I; Tomatis, L; Yamasaki, H; Zabezhinski, M | 1 |
| Koeffler, HP; Ross, HJ; Sato, N; Ueyama, Y | 1 |
| Inokuchi, J; Jimbo, M; Kumamoto, Y; Nagamatsu, A; Shimeno, H | 1 |
| Iversen, OH | 1 |
| Aliño, SF; Almena, A; Barbero, MC; Garcia, M | 1 |
| Esa, AH; Hess, AD; Laulis, MK; May, S; Pettit, GR; Schuchter, LM | 1 |
| Ayaki, H; Enomoto, T; Enomoto, Y; Inoue, H; Kakunaga, T; Nakamori, S | 1 |
| Bungo, M; Fujiki, H; Fujiwara, Y; Kasahara, K; Nakagawa, K; Niimi, S; Nishio, K; Saijo, N; Sugimoto, Y | 1 |
| Clark, JC; Fink, I; Hull, WM; O'Reilly, MA; Pryhuber, GS; Whitsett, JA | 1 |
| Burton, DW; Deftos, LJ; Murray, SS | 1 |
| Diglio, CA; Fitzgerald, LA; Grossi, IM; Honn, KV; Nelson, KK; Taylor, JD; Umbarger, LA | 1 |
| Gamou, S; Hirai, M; Kobayashi, M; Shimizu, N | 1 |
| Alitalo, K; Evan, G; Mäkelä, TP; Saksela, K | 1 |
| Blood, CH; Zetter, BR | 1 |
| Findlay, DM; Michelangeli, VP; Robinson, PJ | 1 |
| Joenje, H; Keizer, HG | 1 |
| Behnke, O; Olsson, L; Sørensen, HR | 1 |
| Gill, TJ; Hattori, A; Kunz, HW; Shinozuka, H; Yokota, K | 1 |
| Bradshaw, TD; Dale, IL; Gescher, A; Pettit, GR | 1 |
| Bradshaw, TD; Gescher, A; Laughton, CA | 1 |
| Denhez, F; Holt, JT; Kim, KY; Kim, SJ; Roberts, AB; Sporn, MB | 1 |
| Dale, IL; Gescher, A | 1 |
| Koeffler, HP; Munker, M; Munker, R; Saxton, RE | 1 |
| Goerttler, K; Loehrke, H | 1 |
| Anisimov, V; Likhachev, A; Loktionov, A; Napalkov, N; Tomatis, L; Zabezhinski, M | 1 |
| Barsky, SH; Gopalakrishna, R | 1 |
| Dale, IL; Gescher, A; Lazenby, CM | 1 |
| Bochner, BS; Rutledge, BK; Schleimer, RP | 1 |
| Gescher, A; Reed, DJ | 1 |
| Takahashi, K; Takenaga, K | 1 |
| Brodie, AE; Gescher, A; Reed, DJ | 1 |
| Kensler, TW; Seed, JL; Trush, MA | 1 |
4 review(s) available for tetradecanoylphorbol acetate and Cancer of Lung
| Article | Year |
|---|---|
Radon-induced cancer: a cell-based model of tumorigenesis due to protracted exposures.
Topics: Animals; Dose-Response Relationship, Radiation; Environmental Exposure; G2 Phase; Humans; Lung Neoplasms; Models, Biological; Neoplasms, Radiation-Induced; Radon; Tetradecanoylphorbol Acetate | 1994 |
Regulation of VIP gene expression in general. Human lung cancer cells in particular.
Topics: Animals; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cell Division; Colforsin; Cyclic AMP; Dactinomycin; Female; Gene Expression Regulation; Humans; Lung Neoplasms; Male; Neoplasm Proteins; Neurosecretory Systems; Nucleic Acid Synthesis Inhibitors; Organ Specificity; Rats; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vasoactive Intestinal Peptide | 1996 |
Expression, regulation, and function of the SPR family of proteins. A review.
Topics: Aging; Amino Acid Sequence; Animals; Calcium; Cell Count; Cell Division; CHO Cells; Consensus Sequence; Cornified Envelope Proline-Rich Proteins; Cricetinae; Cytokines; Digestive System; Epidermis; Gene Expression Regulation, Neoplastic; Humans; Intermediate Filament Proteins; Lung Neoplasms; Membrane Proteins; Molecular Sequence Data; Multigene Family; Neoplasms, Squamous Cell; Proteins; Respiratory System; Retinoids; Sequence Homology, Amino Acid; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured | 1999 |
Cocarcinogenesis.
Topics: 2-Acetylaminofluorene; Animals; Carcinogens; Cell Transformation, Viral; Cocarcinogenesis; Diet; Gastrointestinal Neoplasms; Hormones; Humans; Liver Neoplasms; Lung Neoplasms; Membranes; Methylcholanthrene; Models, Biological; Neoplasms; Nutritional Physiological Phenomena; Oncogenic Viruses; Propionibacterium acnes; Protein Biosynthesis; Retroviridae; Skin Neoplasms; Tetradecanoylphorbol Acetate; Urinary Bladder Neoplasms; Vitamin A | 1979 |
168 other study(ies) available for tetradecanoylphorbol acetate and Cancer of Lung
| Article | Year |
|---|---|
The role of exosomal miR-181b in the crosstalk between NSCLC cells and tumor-associated macrophages.
Topics: Carcinoma, Non-Small-Cell Lung; Cell Movement; Culture Media, Conditioned; Humans; Lung Neoplasms; MicroRNAs; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Microenvironment; Tumor-Associated Macrophages | 2022 |
NETosis in cancer: a critical analysis of the impact of cancer on neutrophil extracellular trap (NET) release in lung cancer patients vs. mice.
Topics: Animals; Cell Line, Tumor; Extracellular Traps; Granulocyte Colony-Stimulating Factor; Humans; Ionomycin; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Neutrophils; Tetradecanoylphorbol Acetate | 2020 |
Platelet-Activating Factor-Receptor Signaling Mediates Targeted Therapies-Induced Microvesicle Particles Release in Lung Cancer Cells.
Topics: A549 Cells; Antioxidants; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell-Derived Microparticles; Humans; Lung Neoplasms; Microvessels; Mitogen-Activated Protein Kinases; Phosphorylation; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled; Signal Transduction; Sphingomyelin Phosphodiesterase; Tetradecanoylphorbol Acetate | 2020 |
Sphingosine kinase-2 Inhibitor ABC294640 Enhances Doxorubicin-Induced Apoptosis of NSCLC Cells via Altering Survivin Expression.
Topics: A549 Cells; Adamantane; Antineoplastic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Survival; Doxorubicin; Drug Resistance, Neoplasm; Drug Synergism; Humans; Inhibitor of Apoptosis Proteins; Lung Neoplasms; Myeloid Cell Leukemia Sequence 1 Protein; Phosphotransferases (Alcohol Group Acceptor); Protein Kinase Inhibitors; Pyridines; Survivin; Tetradecanoylphorbol Acetate | 2018 |
Increased infiltration of macrophages to radioresistant lung cancer cells contributes to the development of the additional resistance of tumor cells to the cytotoxic effects of NK cells.
Topics: Antibodies, Neutralizing; B7-H1 Antigen; Cell Proliferation; Culture Media, Conditioned; Cytotoxicity, Immunologic; Humans; Interleukin-6; Killer Cells, Natural; Ligands; Lung Neoplasms; Macrophages; Neoplastic Stem Cells; NK Cell Lectin-Like Receptor Subfamily K; Radiation Tolerance; Signal Transduction; Tetradecanoylphorbol Acetate | 2018 |
Chemotherapy agents induce tartrate-resistant acid phosphatase 5a contributing to the symptom distress in lung cancer patients.
Topics: Aged; Antineoplastic Agents; Biomarkers; C-Reactive Protein; Carcinoma, Non-Small-Cell Lung; Cell Differentiation; Confusion; Depression; Fatigue; Female; Hemoglobins; Humans; Interleukin-6; Leukocytes; Lung Neoplasms; Macrophages; Male; Middle Aged; Monocytes; Sleep Wake Disorders; Symptom Assessment; Tartrate-Resistant Acid Phosphatase; Tetradecanoylphorbol Acetate; THP-1 Cells | 2019 |
Local and systemic neutrophilic inflammation in patients with lung cancer and chronic obstructive pulmonary disease.
Topics: Aged; Bronchoalveolar Lavage Fluid; Case-Control Studies; Cell Count; Female; Humans; Inflammation; Leukocyte Elastase; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Neutrophils; Peroxidase; Pulmonary Disease, Chronic Obstructive; Reactive Oxygen Species; Tetradecanoylphorbol Acetate | 2013 |
Suppression of the invasive potential of highly malignant tumor cells by KIOM-C, a novel herbal medicine, via inhibition of NF-κB activation and MMP-9 expression.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Enzyme Activation; Humans; I-kappa B Proteins; Lung Neoplasms; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; NF-KappaB Inhibitor alpha; Phytotherapy; Plant Extracts; Plant Preparations; Plants, Medicinal; Tetradecanoylphorbol Acetate; Transcription Factor RelA | 2014 |
Aqueous extract of Bambusae Caulis in Taeniam inhibits PMA-induced tumor cell invasion and pulmonary metastasis: suppression of NF-κB activation through ROS signaling.
Topics: Animals; Antineoplastic Agents; Bambusa; Blotting, Western; Cell Adhesion; Cell Line, Tumor; Cell Movement; Drugs, Chinese Herbal; Lung Neoplasms; Matrix Metalloproteinase 9; Mice; NF-kappa B; Plant Extracts; Signal Transduction; Tetradecanoylphorbol Acetate | 2013 |
Upregulation of COX-2 in the lung cancer promotes overexpression of multidrug resistance protein 4 (MRP4) via PGE2-dependent pathway.
Topics: Animals; Cell Line, Tumor; Cyclooxygenase 2; Dinoprostone; DNA, Complementary; Humans; Lung Neoplasms; Male; Mice; Multidrug Resistance-Associated Proteins; RNA, Messenger; RNA, Small Interfering; Tetradecanoylphorbol Acetate; Up-Regulation | 2014 |
Endothelial podosome rosettes regulate vascular branching in tumour angiogenesis.
Topics: Animals; Basement Membrane; Cell Line, Tumor; Cell Membrane Structures; Cells, Cultured; Endothelial Cells; Green Fluorescent Proteins; HEK293 Cells; HeLa Cells; Humans; Integrin alpha6beta1; Laminin; Lung Neoplasms; Male; Matrix Metalloproteinase 14; Melanoma, Experimental; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Confocal; Microscopy, Fluorescence; Neoplasms; Neovascularization, Pathologic; RNA Interference; Tetradecanoylphorbol Acetate; Vascular Endothelial Growth Factor A | 2014 |
The transcription factor c-Fos coordinates with histone lysine-specific demethylase 2A to activate the expression of cyclooxygenase-2.
Topics: Blotting, Western; Carcinogens; Cell Line, Tumor; Chromatin Immunoprecipitation; Cyclooxygenase 2; F-Box Proteins; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Immunoprecipitation; Jumonji Domain-Containing Histone Demethylases; Lung Neoplasms; Proto-Oncogene Proteins c-fos; Reverse Transcriptase Polymerase Chain Reaction; Tetradecanoylphorbol Acetate | 2015 |
Role of ATM in bystander signaling between human monocytes and lung adenocarcinoma cells.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Ataxia Telangiectasia Mutated Proteins; Bystander Effect; Cell Line, Tumor; DNA Damage; Gamma Rays; Histones; Humans; Image Processing, Computer-Assisted; Lung Neoplasms; Monocytes; RNA, Small Interfering; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection; U937 Cells | 2015 |
Ethanol extract of baked Gardeniae Fructus exhibits in vitro and in vivo anti-metastatic and anti-angiogenic activities in malignant cancer cells: Role of suppression of the NF-κB and HIF-1α pathways.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Gardenia; Human Umbilical Vein Endothelial Cells; Hypoxia-Inducible Factor 1, alpha Subunit; Lung Neoplasms; Matrix Metalloproteinase 13; Matrix Metalloproteinase 9; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Neovascularization, Pathologic; Plant Extracts; Tetradecanoylphorbol Acetate; Transcription Factor RelA | 2016 |
Human renal cancer cells express a novel membrane-bound interleukin-15 that induces, in response to the soluble interleukin-15 receptor alpha chain, epithelial-to-mesenchymal transition.
Topics: Antibodies, Monoclonal; Carcinoma, Renal Cell; Carcinoma, Small Cell; Cell Differentiation; Cell Line, Tumor; Cell Membrane; Epithelial Cells; Flow Cytometry; Humans; Immunotherapy; Interleukin-15; Kidney Neoplasms; Lung Neoplasms; Mesoderm; Neoplasm Metastasis; Receptors, Interleukin-15; Sodium Acetate; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2009 |
Activation of protein kinase C by phorbol 12-myristate 13-acetate suppresses the growth of lung cancer cells through KLF6 induction.
Topics: Carcinoma, Non-Small-Cell Lung; Cell Growth Processes; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Activation; G1 Phase; Humans; Kruppel-Like Factor 6; Kruppel-Like Transcription Factors; Lung Neoplasms; Phosphorylation; Protein Kinase C; Proto-Oncogene Proteins; RNA, Messenger; S Phase; Tetradecanoylphorbol Acetate | 2009 |
Pterostilbene inhibited tumor invasion via suppressing multiple signal transduction pathways in human hepatocellular carcinoma cells.
Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Movement; Gene Expression Regulation, Neoplastic; Humans; JNK Mitogen-Activated Protein Kinases; Liver Neoplasms; Lung Neoplasms; Matrix Metalloproteinase 9; Mice; Mitogen-Activated Protein Kinase 3; Neoplasm Invasiveness; Neoplasm Transplantation; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Signal Transduction; Stilbenes; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transplantation, Heterologous | 2009 |
Plumbagin inhibits TPA-induced MMP-2 and u-PA expressions by reducing binding activities of NF-kappaB and AP-1 via ERK signaling pathway in A549 human lung cancer cells.
Topics: Cell Line, Tumor; Humans; Lung Neoplasms; Matrix Metalloproteinase 2; Matrix Metalloproteinase Inhibitors; Mitogen-Activated Protein Kinase 3; Naphthoquinones; NF-kappa B; Phosphorylation; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Urokinase-Type Plasminogen Activator | 2010 |
Modulation of MMP-2 and MMP-9 by cytokines, mitogens and inhibitors in lung cancer and malignant mesothelioma cell lines.
Topics: Antineoplastic Agents; Cell Line, Tumor; Culture Media; Cytokines; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Lipopolysaccharides; Lung Neoplasms; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mesothelioma; Neoplasm Metastasis; Tetradecanoylphorbol Acetate; Time Factors | 2009 |
Suppression of PMA-induced tumor cell invasion and metastasis by aqueous extract isolated from Prunella vulgaris via the inhibition of NF-kappaB-dependent MMP-9 expression.
Topics: Administration, Oral; Animals; Cell Movement; Cell Nucleus; Lung Neoplasms; Matrix Metalloproteinase 9; Melanoma; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neoplasm Invasiveness; Neoplasm Metastasis; NF-kappa B; Phosphorylation; Plant Extracts; Prunella; Tetradecanoylphorbol Acetate; Translocation, Genetic; Xenograft Model Antitumor Assays | 2010 |
Alpha-mangostin suppresses phorbol 12-myristate 13-acetate-induced MMP-2/MMP-9 expressions via alphavbeta3 integrin/FAK/ERK and NF-kappaB signaling pathway in human lung adenocarcinoma A549 cells.
Topics: Adenocarcinoma; Blotting, Western; Cell Line, Tumor; Cell Movement; Focal Adhesion Kinase 1; Humans; Integrin alphaVbeta3; Lung Neoplasms; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neoplasm Metastasis; NF-kappa B; RNA, Small Interfering; Signal Transduction; Tetradecanoylphorbol Acetate; Xanthones | 2010 |
Phosphorylation of RalB is important for bladder cancer cell growth and metastasis.
Topics: Actins; Animals; Apoptosis; Blotting, Western; Cell Adhesion; Cell Movement; Cell Proliferation; Cyclic AMP-Dependent Protein Kinases; Cytoskeleton; Female; Fluorescent Antibody Technique; Humans; Immunoprecipitation; Lung Neoplasms; Mice; Mice, Nude; Mutagenesis, Site-Directed; Mutation; Phosphorylation; Protein Kinase C; Rabbits; ral GTP-Binding Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Tetradecanoylphorbol Acetate; Urinary Bladder Neoplasms; Wound Healing | 2010 |
Cyclooxygenase-2 up-regulates vascular endothelial growth factor via a protein kinase C pathway in non-small cell lung cancer.
Topics: Adult; Aged; Carbazoles; Carcinoma, Non-Small-Cell Lung; Cell Survival; Cyclic AMP-Dependent Protein Kinases; Cyclooxygenase 2; Enzyme Activators; Female; Humans; Lung Neoplasms; Male; Middle Aged; Prostaglandins E; Protein Kinase C; Pyrroles; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Up-Regulation; Vascular Endothelial Growth Factor A; Xanthones | 2011 |
Inhibitory effect of Trolox on the migration and invasion of human lung and cervical cancer cells.
Topics: Antineoplastic Agents; Antioxidants; Cell Line, Tumor; Cell Movement; Cell Survival; Chromans; Female; HeLa Cells; Humans; Lung Neoplasms; Matrix Metalloproteinase 9; NF-kappa B; Proteolysis; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Transcriptional Activation; Uterine Cervical Neoplasms | 2012 |
A near-infrared fluorescent probe for monitoring ozone and imaging in living cells.
Topics: Animals; Carbocyanines; Cell Line, Tumor; Fluorescent Dyes; Half-Life; Humans; Lung Neoplasms; Macrophages; Magnetic Resonance Spectroscopy; Mice; Microscopy, Confocal; Molecular Imaging; Ozone; Reactive Oxygen Species; Sensitivity and Specificity; Spectroscopy, Near-Infrared; Tetradecanoylphorbol Acetate; Tryptophan | 2012 |
MicroRNA-212 displays tumor-promoting properties in non-small cell lung cancer cells and targets the hedgehog pathway receptor PTCH1.
Topics: Antibodies, Monoclonal; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Gene Expression Regulation, Neoplastic; Hedgehog Proteins; Humans; Lung Neoplasms; MicroRNAs; Patched Receptors; Patched-1 Receptor; Receptors, Cell Surface; RNA Interference; RNA, Small Interfering; Signal Transduction; Tetradecanoylphorbol Acetate | 2012 |
Molecular mechanism depressing PMA-induced invasive behaviors in human lung adenocarcinoma cells by cis- and trans-cinnamic acid.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Carcinogens; Cell Line, Tumor; Cinnamates; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; MAP Kinase Signaling System; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Models, Biological; Neoplasm Invasiveness; Neoplasm Proteins; Osmolar Concentration; Stereoisomerism; Tetradecanoylphorbol Acetate; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2; Urokinase-Type Plasminogen Activator | 2013 |
The effect of beta-carotene on lung and skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; beta Carotene; Carcinogens; Dose-Response Relationship, Drug; Ferrets; Lung Neoplasms; Mice; Nicotiana; Papilloma; Precancerous Conditions; Skin Neoplasms; Smoke; Tetradecanoylphorbol Acetate | 2002 |
Non-small cell lung cancer-derived soluble mediators enhance apoptosis in activated T lymphocytes through an I kappa B kinase-dependent mechanism.
Topics: Adenocarcinoma; Apoptosis; Carcinoma, Non-Small-Cell Lung; CD3 Complex; Humans; I-kappa B Kinase; I-kappa B Proteins; Ionomycin; Jurkat Cells; Lung Neoplasms; NF-kappa B; Protein Serine-Threonine Kinases; T-Lymphocytes; Tetradecanoylphorbol Acetate | 2003 |
Cyclooxygenase-2 in human non-small cell lung cancer.
Topics: Aged; Butyrates; Carcinoma, Non-Small-Cell Lung; Cyclooxygenase 2; Female; Humans; Immunoblotting; Immunohistochemistry; Inflammation Mediators; Isoenzymes; Lung Neoplasms; Male; Membrane Proteins; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Reverse Transcriptase Polymerase Chain Reaction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2003 |
Induction of tumors of the liver, lung, ovary and adrenal in adult mice after brief maternal gestational exposure to inorganic arsenic: promotional effects of postnatal phorbol ester exposure on hepatic and pulmonary, but not dermal cancers.
Topics: Adrenal Gland Neoplasms; Animals; Arsenic; Female; Fetus; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Mice; Mice, Inbred C3H; Organ Specificity; Ovarian Neoplasms; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2004 |
Expression of microsomal prostaglandin E synthase-1 in intestinal type gastric adenocarcinoma and in gastric cancer cell lines.
Topics: Adenocarcinoma; Blotting, Northern; Blotting, Western; Carcinogens; Cyclooxygenase 2; Dinoprostone; Enzyme Induction; Gastric Mucosa; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Immunoenzyme Techniques; Interleukin-1; Intestines; Intramolecular Oxidoreductases; Isoenzymes; Lung Neoplasms; Membrane Proteins; Microsomes; Prostaglandin-E Synthases; Prostaglandin-Endoperoxide Synthases; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2003 |
The antiangiogenic agent SU5416 down-regulates phorbol ester-mediated induction of cyclooxygenase 2 expression by inhibiting nicotinamide adenine dinucleotide phosphate oxidase activity.
Topics: Angiogenesis Inhibitors; Carcinoma, Non-Small-Cell Lung; Cyclooxygenase 2; Down-Regulation; Drug Interactions; Enzyme Induction; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Indoles; Isoenzymes; Lung Neoplasms; Membrane Proteins; NADPH Oxidases; Prostaglandin-Endoperoxide Synthases; Pyrroles; Superoxides; Tetradecanoylphorbol Acetate | 2003 |
Methanolic extract of adlay seed suppresses COX-2 expression of human lung cancer cells via inhibition of gene transcription.
Topics: Animals; Carcinoma, Non-Small-Cell Lung; Coix; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Gene Expression Regulation; Humans; Isoenzymes; Lung Neoplasms; Male; Membrane Proteins; Methanol; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Plant Extracts; Prostaglandin-Endoperoxide Synthases; Seeds; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2003 |
Cooperation between PKC-alpha and PKC-epsilon in the regulation of JNK activation in human lung cancer cells.
Topics: Animals; Carbazoles; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cell Membrane; Cytoplasm; Humans; Indoles; Isoenzymes; JNK Mitogen-Activated Protein Kinases; Lung Neoplasms; Maleimides; Mice; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-epsilon; rac1 GTP-Binding Protein; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2004 |
Fibronectin alters cell survival and intracellular signaling of confluent A549 cultures after irradiation.
Topics: Cell Communication; Cell Line, Tumor; Cell Survival; Culture Media; Extracellular Matrix; Fibronectins; Flow Cytometry; Humans; Lung Neoplasms; Tetradecanoylphorbol Acetate | 2004 |
Cyclooxygenase (COX)-2 inhibitor celecoxib abrogates TNF-induced NF-kappa B activation through inhibition of activation of I kappa B alpha kinase and Akt in human non-small cell lung carcinoma: correlation with suppression of COX-2 synthesis.
Topics: Carcinogens; Carcinoma, Non-Small-Cell Lung; Celecoxib; Cell Line, Tumor; Cyclin D1; Cyclooxygenase Inhibitors; Enzyme Activation; Genes, Reporter; Humans; I-kappa B Kinase; I-kappa B Proteins; Interleukin-1; Lipopolysaccharides; Lung Neoplasms; MAP Kinase Signaling System; Matrix Metalloproteinase Inhibitors; Neoplasm Proteins; NF-kappa B; NF-KappaB Inhibitor alpha; Okadaic Acid; Phosphorylation; Promoter Regions, Genetic; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyrazoles; Receptors, Tumor Necrosis Factor; Sulfonamides; Tetradecanoylphorbol Acetate; TNF Receptor-Associated Factor 1; TNF Receptor-Associated Factor 2; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2004 |
Autocrine and paracrine regulation of interleukin-8 expression in lung cancer cells.
Topics: Antibodies; Autocrine Communication; Carcinogens; Coculture Techniques; Dose-Response Relationship, Drug; Fibroblasts; Gene Expression; Humans; Interleukin-1; Interleukin-8; Lung Neoplasms; Macrophages, Alveolar; Monocytes; NF-kappa B; Paracrine Communication; Pneumonia; Respiratory Mucosa; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2005 |
Mitogen regulated induction of FRA-1 proto-oncogene is controlled by the transcription factors binding to both serum and TPA response elements.
Topics: Activating Transcription Factors; Blood Proteins; Breast Neoplasms; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Mitogens; Promoter Regions, Genetic; Proto-Oncogene Mas; Proto-Oncogene Proteins c-fos; Serum Response Element; Tetradecanoylphorbol Acetate; Transcription Factors; Tumor Cells, Cultured | 2005 |
Regulation of the release and function of tumor cell-derived soluble CD44.
Topics: Antigens, CD; Carcinoma, Squamous Cell; Cell Line, Tumor; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Hyaluronan Receptors; Hyaluronic Acid; Lung Neoplasms; Metalloproteases; Recombinant Proteins; Tetradecanoylphorbol Acetate | 2005 |
N-acetylcysteine conjugate of phenethyl isothiocyanate enhances apoptosis in growth-stimulated human lung cells.
Topics: Adenocarcinoma; Animals; Apoptosis; Cell Line, Tumor; Cysteine; Dose-Response Relationship, Drug; Enzyme Activation; Humans; JNK Mitogen-Activated Protein Kinases; Lung; Lung Neoplasms; Mice; Mice, Inbred A; Tetradecanoylphorbol Acetate; Thiocarbamates; Transcription Factor AP-1; Transfection; Tumor Suppressor Protein p53 | 2005 |
Role of protein kinase C in expression of granulocyte-colony stimulating factor and granulocyte macrophage-colony stimulating factor in lung cancer cells.
Topics: Apoptosis; Enzyme Activation; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Isoenzymes; Lung Neoplasms; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NF-kappa B; Protein Kinase C; Protein Kinase Inhibitors; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2005 |
Tumour-derived microvesicles carry several surface determinants and mRNA of tumour cells and transfer some of these determinants to monocytes.
Topics: Adenocarcinoma; Antigens, Neoplasm; Apoptosis; Basigin; Cell Line, Tumor; Cell Membrane; Cell Survival; Chemotaxis; Colorectal Neoplasms; Gene Expression Profiling; Genes, MHC Class I; HLA Antigens; Humans; Hyaluronan Receptors; Immunophenotyping; Lung Neoplasms; Membrane Proteins; Monocytes; Neoplasm Proteins; Neoplasms; Pancreatic Neoplasms; Particle Size; Receptors, Chemokine; Receptors, Cytokine; RNA, Messenger; Tetradecanoylphorbol Acetate | 2006 |
Differential effect of bryostatin 1 and phorbol 12-myristate 13-acetate on HOP-92 cell proliferation is mediated by down-regulation of protein kinase Cdelta.
Topics: Bryostatins; Carcinoma, Non-Small-Cell Lung; Cell Growth Processes; Cell Line, Tumor; Down-Regulation; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Macrolides; Protein Kinase C-delta; Tetradecanoylphorbol Acetate | 2006 |
Differential regulation of RANTES and IL-8 expression in lung adenocarcinoma cells.
Topics: Adenocarcinoma; Blotting, Northern; Blotting, Western; Carcinogens; Cell Line, Tumor; Chemokine CCL5; Electrophoretic Mobility Shift Assay; Humans; Interleukin-8; Lung Neoplasms; Mitogen-Activated Protein Kinases; NF-kappa B; Promoter Regions, Genetic; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transfection; Tumor Necrosis Factor-alpha | 2007 |
Protein kinase C-ERK1/2 signal pathway switches glucose depletion-induced necrosis to apoptosis by regulating superoxide dismutases and suppressing reactive oxygen species production in A549 lung cancer cells.
Topics: Acetylcysteine; Antioxidants; Apoptosis; Apoptosis Inducing Factor; Caspase 3; Caspase 9; Catalase; Cell Line, Tumor; Cell Survival; Endodeoxyribonucleases; Enzyme Activation; Enzyme Induction; Enzyme Stability; Extracellular Signal-Regulated MAP Kinases; Glucose; HMGB1 Protein; Humans; Lung Neoplasms; Mitochondria; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Necrosis; Protein Kinase C; Reactive Oxygen Species; Signal Transduction; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Time Factors | 2007 |
Antioxidant activity of Vaccinium stamineum: exhibition of anticancer capability in human lung and leukemia cells.
Topics: Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Cell Line, Tumor; Cell Proliferation; Chromatography, High Pressure Liquid; Enzyme Activation; Flavonoids; Fruit; Humans; Leukemia; Lung Neoplasms; Mice; Mitogen-Activated Protein Kinases; NF-kappa B; Phosphorylation; Plant Extracts; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Ultraviolet Rays; Vaccinium | 2007 |
Antibody microarray analysis of inflammatory mediator release by human leukemia T-cells and human non small cell lung cancer cells.
Topics: Antibodies; Carcinoma, Non-Small-Cell Lung; Cell Line; Cross Reactions; Enzyme-Linked Immunosorbent Assay; Humans; Inflammation Mediators; Leukemia, T-Cell; Lung Neoplasms; Phytohemagglutinins; Sensitivity and Specificity; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2007 |
Nucleolin regulates c-Jun/Sp1-dependent transcriptional activation of cPLA2alpha in phorbol ester-treated non-small cell lung cancer A549 cells.
Topics: Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; GC Rich Sequence; Gene Expression Regulation, Neoplastic; Group IV Phospholipases A2; Humans; Lung Neoplasms; Nucleolin; Phosphoproteins; Promoter Regions, Genetic; Proto-Oncogene Proteins c-jun; RNA-Binding Proteins; Sp1 Transcription Factor; Tetradecanoylphorbol Acetate; Transcription Factors; Transcription, Genetic; Transcriptional Activation | 2008 |
Wogonin, a bioactive flavonoid in herbal tea, inhibits inflammatory cyclooxygenase-2 gene expression in human lung epithelial cancer cells.
Topics: Anti-Inflammatory Agents; Beverages; Cell Line, Tumor; Cell Survival; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Epithelial Cells; Flavanones; Gene Expression Regulation, Enzymologic; Humans; Lung Neoplasms; Promoter Regions, Genetic; Proto-Oncogene Proteins c-jun; Tetradecanoylphorbol Acetate; Transcription Factor AP-1 | 2008 |
Lymphokines produced by herpesvirus-transformed marmoset monkey lymphoid cell lines. I. Characterization of a constitutively produced interferon.
Topics: Animals; Callitrichinae; Cell Line; Cell Transformation, Viral; Herpesviridae; Herpesvirus 2, Saimiriine; Humans; Interferon-gamma; Interferons; Kinetics; Lung Neoplasms; Lymphocytes; Species Specificity; Tetradecanoylphorbol Acetate; Vesicular stomatitis Indiana virus | 1984 |
Can prenatal X-irradiation in mice act as an initiator stimulus in a modified 2-stage Berenblum/Mottram experiment with postnatal promotion with phorbol ester TPA?
Topics: Adenoma; Animals; Carcinoma, Hepatocellular; Cocarcinogenesis; Female; Fetus; Leukemia; Liver Neoplasms; Lung Neoplasms; Maternal-Fetal Exchange; Mice; Ovarian Diseases; Phorbols; Pregnancy; Prostaglandins; Radiation, Ionizing; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; X-Rays | 1980 |
A clinically relevant canine lung cancer model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Delayed-Action Preparations; Disease Models, Animal; Dogs; Lung Neoplasms; Methods; Methylcholanthrene; Methylnitrosourea; Neoplasms, Experimental; Radioisotopes; Tetradecanoylphorbol Acetate | 1981 |
Induction of cytoskeleton-associated proteins during differentiation of human myeloid leukemic cell lines.
Topics: Carcinoma, Small Cell; Cell Differentiation; Cell Line; Fluorescent Antibody Technique; Humans; Intermediate Filament Proteins; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lung Neoplasms; Neoplasm Proteins; Tetradecanoylphorbol Acetate; Vimentin | 1982 |
Protective effects of ellagic acid and other plant phenols on benzo[a]pyrene-induced neoplasia in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoma; Animals; Benzo(a)pyrene; Benzopyrans; Benzopyrenes; Carcinogens; Chlorogenic Acid; Cinnamates; Coumaric Acids; Ellagic Acid; Lung Neoplasms; Male; Mice; Mice, Inbred Strains; Plants, Medicinal; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1983 |
Differential effects of 12-O-tetradecanoylphorbol-13-acetate on cultured normal and neoplastic human bronchial epithelial cells.
Topics: Cell Division; Cell Line; Cell Survival; Cells, Cultured; Clone Cells; Epithelial Cells; Epithelium; Humans; Kinetics; Lung; Lung Neoplasms; Phorbols; Tetradecanoylphorbol Acetate | 1984 |
Butylated hydroxyanisole and lung tumor development in A/J mice.
Topics: Animals; Anisoles; Benzo(a)pyrene; Butylated Hydroxyanisole; Butylated Hydroxytoluene; Cell Division; Cocarcinogenesis; Dimethylnitrosamine; Lung Neoplasms; Male; Mice; Mice, Inbred Strains; Tetradecanoylphorbol Acetate; Urethane | 1984 |
Effect of 12-O-tetradecanoylphorbol-13-acetate on polyamine metabolism in mice sensitive and resistant to lung-adenoma.
Topics: Adenoma; Animals; Lung; Lung Neoplasms; Mice; Mice, Inbred C3H; Ornithine Decarboxylase; Phorbols; Polyamines; Tetradecanoylphorbol Acetate | 1983 |
The injurious effect of neutrophils on pneumocytes in vitro.
Topics: Animals; Catalase; Cell Line; Cell Survival; Cells, Cultured; Chemotaxis, Leukocyte; Culture Media; Cytotoxicity, Immunologic; DNA; Extracellular Matrix; Humans; Lung Neoplasms; Lymphocyte Activation; Neutrophils; Protease Inhibitors; Protein Biosynthesis; Pulmonary Alveoli; Rats; Superoxide Dismutase; Tetradecanoylphorbol Acetate | 1984 |
Profound depression of alveolar macrophage functions in bronchial carcinoma.
Topics: Carcinoma, Bronchogenic; Humans; In Vitro Techniques; Lung Neoplasms; Macrophage Activation; Macrophages; Male; Middle Aged; Phagocytosis; Pulmonary Alveoli; Staphylococcus aureus; Tetradecanoylphorbol Acetate | 1984 |
Application of tumor, bacterial and parasite susceptibility assays to study immune alterations induced by environmental chemicals.
Topics: Animals; Bacterial Infections; Benzopyrenes; Diethylstilbestrol; Endotoxins; Environmental Pollutants; Female; Immunity; Listeriosis; Lung Neoplasms; Male; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Parasitic Diseases; Tetradecanoylphorbol Acetate; Trichinellosis | 1982 |
Tumorigenic activity of benzo(e)pyrene derivatives on mouse skin and in newborn mice.
Topics: Animals; Animals, Newborn; Benzopyrenes; Biotransformation; Dihydroxydihydrobenzopyrenes; Female; Liver Neoplasms; Lung Neoplasms; Male; Mice; Neoplasms, Experimental; Papilloma; Pregnancy; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1980 |
Cyclic AMP increases the release of parathyroid hormone-related protein from a lung-cancer cell line.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Bucladesine; Calcitonin; Carcinoma, Squamous Cell; Cell Line; Colforsin; Cyclic AMP; Humans; Kinetics; Lung Neoplasms; Neoplasm Proteins; Parathyroid Hormone-Related Protein; Protein Biosynthesis; Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Comparative two-stage cancer tests of ethylene oxide, N-(2-hydroxyethyl)-N-nitrosourea and X-rays.
Topics: Animals; Carcinogenicity Tests; Carcinogens; Ethylene Oxide; Ethylnitrosourea; Lung Neoplasms; Male; Mice; Neoplasms, Radiation-Induced; Skin Neoplasms; Tetradecanoylphorbol Acetate; X-Rays | 1994 |
Functional hyaluronan receptors are expressed on a squamous cell lung carcinoma cell line but not on other lung carcinoma cell lines.
Topics: Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Carrier Proteins; Culture Media, Conditioned; Fibroblasts; Humans; Hyaluronan Receptors; Hyaluronic Acid; Lung Neoplasms; Neoplasm Proteins; Receptors, Cell Surface; Receptors, Lymphocyte Homing; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Up-Regulation | 1995 |
In vitro investigation on proliferative cystic keratinizing squamous lesions in the rat lung.
Topics: Animals; Cell Division; Cells, Cultured; Cysts; Female; Keratins; Lung; Lung Neoplasms; Rats; Tetradecanoylphorbol Acetate | 1993 |
Bombesin stimulates c-fos and c-jun mRNAs in small cell lung cancer cells.
Topics: Bombesin; Carcinoma, Small Cell; Gastrin-Releasing Peptide; Gene Expression; Genes, fos; Genes, jun; Humans; Lung Neoplasms; Oligopeptides; Peptide Fragments; Peptides; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Opioids induce while nicotine suppresses apoptosis in human lung cancer cells.
Topics: Apoptosis; DNA Damage; DNA, Neoplasm; Drug Synergism; Hexamethonium; Humans; Lung Neoplasms; Methadone; Morphine; Nicotine; Receptors, Cholinergic; Sphingosine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Calcium ionophore A23187 inhibits ACTH secretion from a human small cell lung cancer cell line, COR-L103.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenocorticotropic Hormone; Calcimycin; Carcinoma, Small Cell; Cell Line; Corticotropin-Releasing Hormone; Dexamethasone; Dose-Response Relationship, Drug; Humans; Immunoradiometric Assay; Interleukin-1; Interleukin-2; Kinetics; Lung Neoplasms; Pro-Opiomelanocortin; Somatostatin; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured | 1995 |
Modulation of human melanoma cell metastasis and adhesion may involve integrin phosphorylation mediated through protein kinase C.
Topics: Amino Acids; Animals; Cell Adhesion; Cell Line; Collagen; Fibronectins; Humans; Integrins; Laminin; Lung Neoplasms; Melanoma; Mice; Mice, SCID; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate; Transplantation, Heterologous; Tumor Cells, Cultured | 1994 |
Tobacco smoke tumor promoters, catechol and hydroquinone, induce oxidative regulation of protein kinase C and influence invasion and metastasis of lung carcinoma cells.
Topics: Animals; Carcinogens; Catechols; Cell Membrane; Chelating Agents; Cytosol; Hydroquinones; Lung Neoplasms; Mice; Mice, Inbred C57BL; Neoplasm Invasiveness; Neoplasm Metastasis; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Inbred Lew; Smoke; Smoking; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Genistein modulates the decreased drug accumulation in non-P-glycoprotein mediated multidrug resistant tumour cells.
Topics: Alkaloids; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Carrier Proteins; Daunorubicin; Doxorubicin; Drug Resistance; Etoposide; Genistein; Humans; Hydrogen-Ion Concentration; Isoflavones; Lung Neoplasms; Membrane Glycoproteins; Neoplasms; Protein-Tyrosine Kinases; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
The role of protein kinase C isoenzymes in the growth inhibition caused by bryostatin 1 in human A549 lung and MCF-7 breast carcinoma cells.
Topics: Antineoplastic Agents; Blotting, Western; Breast Neoplasms; Bryostatins; Cell Division; Chromatography; Durapatite; Enzyme Activation; Humans; Isoenzymes; Lactones; Lung Neoplasms; Macrolides; Protein Kinase C; Subcellular Fractions; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
[Anti-tumor promoting activities of kampo prescriptions. II. Inhibitory effects of souseiryu-to on two-stage carcinogenesis of mouse skin tumors and mouse pulmonary tumors].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Viral; Cell Cycle; Drug Screening Assays, Antitumor; Drugs, Chinese Herbal; Female; Liver Neoplasms, Experimental; Lung Neoplasms; Mice; Mice, Inbred ICR; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1994 |
Phorbol esters regulate preprogastrin-releasing peptide messenger RNA in small cell lung cancer cells.
Topics: Base Sequence; Carcinoma, Small Cell; Cell Division; Enzyme Activation; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Molecular Sequence Data; Peptide Biosynthesis; Peptides; Promoter Regions, Genetic; Protein Kinase C; Protein Precursors; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate | 1993 |
Corticotropin-releasing hormone, proopiomelanocortin, and glucocorticoid receptor gene expression in adrenocorticotropin-producing tumors in vitro.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenoma; Adrenocorticotropic Hormone; Adult; Aged; Arginine Vasopressin; Breast Neoplasms; Corticotropin-Releasing Hormone; Cushing Syndrome; Dexamethasone; Esophageal Neoplasms; Female; Gene Expression; Humans; Hydrocortisone; Lung Neoplasms; Male; Metyrapone; Middle Aged; Pituitary Neoplasms; Pro-Opiomelanocortin; Receptors, Glucocorticoid; RNA, Messenger; Tetradecanoylphorbol Acetate | 1993 |
Anti-tumor promoting activities of natural products. II. Inhibitory effects of digitoxin on two-stage carcinogenesis of mouse skin tumors and mouse pulmonary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Digitoxin; Female; Glycerol; Lung Neoplasms; Mice; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1993 |
Activation of potassium channels by hypoxia and reoxygenation in the human lung adenocarcinoma cell line A549.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetylcysteine; Adenocarcinoma; Alkaloids; Free Radical Scavengers; Humans; Hypoxia; Isoquinolines; Lung Neoplasms; Oxidation-Reduction; Oxygen; Piperazines; Potassium Channels; Protein Kinase Inhibitors; Protein Kinases; Staurosporine; Tetradecanoylphorbol Acetate; Tetraethylammonium; Tetraethylammonium Compounds; Time Factors; Tumor Cells, Cultured | 1993 |
Transplacental carcinogenicity of cisplatin: initiation of skin tumors and induction of other preneoplastic and neoplastic lesions in SENCAR mice.
Topics: Animals; Cisplatin; Cocarcinogenesis; Female; Kidney Neoplasms; Lung Neoplasms; Male; Maternal-Fetal Exchange; Mice; Mice, Inbred Strains; Papilloma; Precancerous Conditions; Pregnancy; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1993 |
Chemoprevention of lung and skin cancer by Beta vulgaris (beet) root extract.
Topics: Animals; Anticarcinogenic Agents; Betacyanins; Female; Indoles; Lung Neoplasms; Mice; Mice, Inbred ICR; Pigments, Biological; Plant Extracts; Plant Roots; Plants, Edible; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1996 |
Tamoxifen antagonizes proliferation and invasion of estrogen receptor-negative metastatic follicular thyroid cancer cells via protein kinase C.
Topics: Alkaloids; Antineoplastic Agents, Hormonal; Cell Division; Drug Interactions; Enzyme Inhibitors; Estrogen Antagonists; Humans; Lung Neoplasms; Neoplasm Invasiveness; Protein Kinase C; Receptors, Estrogen; Staurosporine; Tamoxifen; Tetradecanoylphorbol Acetate; Thyroid Neoplasms; Tumor Cells, Cultured | 1996 |
Lung cancer cell lines inhibit leukotriene B4 production by human polymorphonuclear leukocytes at the level of phospholipase A2.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Arachidonic Acid; Calcimycin; Calcium; Coculture Techniques; Cyclooxygenase Inhibitors; Dinoprostone; Erythrocytes; Humans; Hydroxyeicosatetraenoic Acids; Indomethacin; Ionophores; Leukotriene B4; Lipoxygenase; Lung Neoplasms; Neutrophils; Phospholipases A; Phospholipases A2; Subcellular Fractions; Superoxides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1996 |
Superoxide release and NADPH oxidase components in mature human phagocytes: correlation between functional capacity and amount of functional proteins.
Topics: Adult; Bronchoalveolar Lavage Fluid; Eosinophilia; Eosinophils; Humans; In Vitro Techniques; Kinetics; Lung Neoplasms; Macrophages, Alveolar; Membrane Glycoproteins; Membrane Transport Proteins; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; NADPH Dehydrogenase; NADPH Oxidase 2; NADPH Oxidases; Neutrophils; Phagocytes; Phosphoproteins; Superoxides; Tetradecanoylphorbol Acetate | 1996 |
P-selectin-mediated attachment of small cell lung carcinoma to endothelial cells.
Topics: Animals; Carcinogens; Carcinoma, Small Cell; Cattle; Cell Adhesion; Cell Line; Endothelium, Vascular; Humans; Lung Neoplasms; P-Selectin; Tetradecanoylphorbol Acetate | 1996 |
Control of proteinase expression by phorbol-ester- and Fos-dependent pathways in human non-small-cell lung-cancer cells.
Topics: Carcinoma, Non-Small-Cell Lung; Cell Differentiation; Cell Division; Cell Size; Diethylstilbestrol; DNA Primers; Endopeptidases; Estrogens, Non-Steroidal; Gene Expression Regulation, Enzymologic; Humans; Immunoblotting; Lung Neoplasms; Protein Kinase C; Proto-Oncogene Proteins c-fos; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1997 |
In vitro and in vivo studies of murine sarcoma cells after prolonged treatment with promoting phorbol ester TPA.
Topics: Animals; Blotting, Western; Carcinogens; Cell Adhesion; Cell Movement; Female; Lung Neoplasms; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Phosphorylation; Protein Kinase C; Sarcoma, Experimental; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1997 |
[Effects of curcumin derivatives on the GJIC of normal and tumor cells].
Topics: 3T3 Cells; Adenocarcinoma; Animals; Antineoplastic Agents; Carcinogens; Cell Communication; Cells, Cultured; Cricetinae; Curcumin; Fetus; Gap Junctions; Humans; Liver; Lung; Lung Neoplasms; Mice; Rats; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1996 |
Cathepsin B and cysteine proteinase inhibitors in human lung cancer cell lines.
Topics: Carcinogens; Carcinoma, Large Cell; Carcinoma, Non-Small-Cell Lung; Cathepsin B; Cystatin A; Cystatin B; Cystatin C; Cystatins; Cysteine Proteinase Inhibitors; Electrophoresis, Polyacrylamide Gel; Humans; Insulin-Like Growth Factor I; Isoelectric Focusing; Isoenzymes; Lung Neoplasms; Molecular Weight; Protein Kinase C; Tetradecanoylphorbol Acetate | 1997 |
Inhibitory effects of shouseiryu-to on two-stage carcinogenesis. II. Anti-tumor-promoting activities of lignans from Asiasarum heterotropoides var. mandshuricum.
Topics: Animals; Anticarcinogenic Agents; Antigens, Viral; Cell Line; Cell Transformation, Neoplastic; Dioxoles; Female; Furans; Lignans; Lung Neoplasms; Mice; Mice, Inbred ICR; Phenols; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1997 |
Effects of transforming growth factor-beta 1 and phorbol ester on PAI-1 and PA genes in human lung cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Blotting, Northern; Bronchi; Carcinoma, Non-Small-Cell Lung; Cells, Cultured; DNA Probes; Enzyme Inhibitors; Extracellular Matrix; Fibronectins; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Plasminogen Activator Inhibitor 1; Plasminogen Activators; Protein Serine-Threonine Kinases; RNA, Messenger; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta; Tumor Cells, Cultured | 1997 |
Plasma membrane alterations and cytoskeletal changes in apoptosis.
Topics: Actins; Annexin A5; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Membrane; Chromatin; Cytoskeleton; Ethylmaleimide; Humans; Keratins; Kinetin; Lung Neoplasms; Neuroblastoma; Phosphatidylserines; Purines; Roscovitine; Tetradecanoylphorbol Acetate; Tubulin; Tumor Cells, Cultured; Vimentin | 1997 |
Identification of early growth response gene-1 (Egr-1) as a phorbol myristate acetate-induced gene in lung cancer cells by differential mRNA display.
Topics: Base Sequence; Carcinogens; Carcinoma, Non-Small-Cell Lung; Cell Differentiation; DNA-Binding Proteins; Early Growth Response Protein 1; Gene Expression Regulation, Neoplastic; Humans; Immediate-Early Proteins; Lung Neoplasms; Molecular Sequence Data; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription Factors; Tumor Cells, Cultured | 1997 |
Requirement for matrix metalloproteinase-9 (gelatinase B) expression in metastasis by murine prostate carcinoma.
Topics: Animals; Carcinoma; Collagenases; Female; Gelatinases; Lung Neoplasms; Male; Matrix Metalloproteinase 9; Mice; Mice, Nude; Prostatic Neoplasms; RNA, Catalytic; RNA, Messenger; Tetradecanoylphorbol Acetate; Transfection; Transforming Growth Factor beta | 1998 |
Human annexin 1 is highly expressed during the differentiation of the epithelial cell line A 549: involvement of nuclear factor interleukin 6 in phorbol ester induction of annexin 1.
Topics: Adenocarcinoma; Annexin A1; CCAAT-Enhancer-Binding Proteins; Cell Differentiation; Dexamethasone; Dipeptidyl Peptidase 4; DNA-Binding Proteins; Epithelial Cells; Glucocorticoids; Hormone Antagonists; Humans; Lung Neoplasms; Mifepristone; Nuclear Proteins; Promoter Regions, Genetic; Recombinant Fusion Proteins; Sequence Deletion; Tetradecanoylphorbol Acetate; Transcription Factors; Transcriptional Activation; Transfection; Tumor Cells, Cultured | 1998 |
Induction of inhibitory Smad6 and Smad7 mRNA by TGF-beta family members.
Topics: Activins; Animals; Bone Morphogenetic Proteins; Cell Line; DNA-Binding Proteins; Drug Synergism; Epidermal Growth Factor; Epithelial Cells; Gene Expression; Humans; Inhibins; Keratinocytes; Lung; Lung Neoplasms; Mink; RNA, Messenger; Signal Transduction; Smad6 Protein; Smad7 Protein; Tetradecanoylphorbol Acetate; Trans-Activators; Transforming Growth Factor beta; Tumor Cells, Cultured | 1998 |
Differential regulation of eotaxin expression by TNF-alpha and PMA in human monocytic U-937 cells.
Topics: Adenocarcinoma; Cell Line; Cells, Cultured; Chemokine CCL11; Chemokines, CC; Chemotactic Factors, Eosinophil; Cytokines; Epithelial Cells; Gene Expression Regulation; Humans; Interferon-gamma; Interleukin-1; Interleukin-4; Kinetics; Lipopolysaccharides; Lung Neoplasms; Monocytes; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Transcription, Genetic; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1998 |
Regulation of integrin-mediated adhesion by muscarinic acetylcholine receptors and protein kinase C in small cell lung carcinoma.
Topics: Atropine; Carbachol; Carcinoma, Small Cell; Cell Adhesion; Extracellular Matrix Proteins; Fluorescent Antibody Technique; In Vitro Techniques; Integrins; Lung Neoplasms; Muscarinic Agonists; Muscarinic Antagonists; Protein Kinase C; Receptors, Muscarinic; Serum Albumin, Bovine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1998 |
Matrilysin expression and function in airway epithelium.
Topics: Amides; Animals; Cell Movement; Cystic Fibrosis; Enzyme Induction; Epithelial Cells; Female; Gene Expression Regulation, Enzymologic; Humans; Lung; Lung Diseases; Lung Neoplasms; Matrix Metalloproteinase 7; Metalloendopeptidases; Mice; Mice, Knockout; Protease Inhibitors; Pulmonary Alveoli; Tetradecanoylphorbol Acetate; Trachea; Tumor Cells, Cultured; Tyrosine | 1998 |
Human achaete-scute homologue 1 (HASH-1) is downregulated in differentiating neuroblastoma cells.
Topics: Basic Helix-Loop-Helix Transcription Factors; Blotting, Northern; Carcinoma, Small Cell; Carrier Proteins; Cell Differentiation; Cell Size; DNA-Binding Proteins; Down-Regulation; GAP-43 Protein; Growth Substances; Humans; Lung Neoplasms; Membrane Proteins; Neurites; Neuroblastoma; Neurons; Neuropeptide Y; Receptor, trkA; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription Factors; Transfection; Tretinoin; Tumor Cells, Cultured | 1999 |
Angiogenic capacity and lung-colonizing potential in vivo is increased in weakly metastatic B16F1 cells and decreased in highly metastatic BL6 cells by phorbol esters.
Topics: Animals; Carcinogens; Endothelial Growth Factors; Fibroblast Growth Factors; Lung Neoplasms; Lymphokines; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Neoplasm Transplantation; Neovascularization, Pathologic; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1998 |
Acrolein causes inhibitor kappaB-independent decreases in nuclear factor kappaB activation in human lung adenocarcinoma (A549) cells.
Topics: Acrolein; Adenocarcinoma; Cell Division; DNA-Binding Proteins; Electrophoresis, Polyacrylamide Gel; Humans; I-kappa B Proteins; Lung Neoplasms; Maleates; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1999 |
Regulation of human airway mucins by acrolein and inflammatory mediators.
Topics: Acrolein; Carcinoma, Mucoepidermoid; Dinoprostone; Gene Expression Regulation; Humans; Hydroxyeicosatetraenoic Acids; Inflammation; Kinetics; Lung Neoplasms; Mucin 5AC; Mucin-5B; Mucins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1999 |
Cancer chemopreventive agents (antitumor-promoters) from Ajuga decumbens.
Topics: 4-Nitroquinoline-1-oxide; Animals; Antineoplastic Agents, Phytogenic; Antiviral Agents; Carcinogens; Female; Glycerol; Herpesvirus 4, Human; Lung Neoplasms; Mice; Mice, Inbred ICR; Papilloma; Plants, Medicinal; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1999 |
Differential effect of retinoic acid on growth regulation by phorbol ester in human cancer cell lines.
Topics: Breast Neoplasms; Cell Cycle; Cell Division; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Gene Expression Regulation, Neoplastic; Humans; JNK Mitogen-Activated Protein Kinases; Lung Neoplasms; Mitogen-Activated Protein Kinases; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Tretinoin; Tumor Cells, Cultured | 1999 |
Cytokine biosynthesis by tumor-infiltrating T lymphocytes from human non-small-cell lung carcinoma.
Topics: Adenocarcinoma; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; CD3 Complex; Cytokines; Gene Expression Regulation; Humans; Interleukin-2; Ionomycin; Lung Neoplasms; Lymphocyte Activation; Lymphocytes, Tumor-Infiltrating; Muromonab-CD3; T-Lymphocytes; Tetradecanoylphorbol Acetate | 2000 |
Evidence of mucin secretion in human lung adenocarcinoma cell lines NCIH650 and NCIH2077 and effect of select secretagogues on mucin secretion.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenocarcinoma; Blotting, Western; Enzyme-Linked Immunosorbent Assay; Glucosamine; Humans; Ionomycin; Leukocyte Elastase; Lung Neoplasms; Mucins; Tetradecanoylphorbol Acetate; Tritium; Tumor Cells, Cultured | 1999 |
Anti-tumor-promoting activity of lignans from the aerial part of Saussurea medusa.
Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Administration, Topical; Animals; Antineoplastic Agents, Phytogenic; Asteraceae; Cells, Cultured; Disease Models, Animal; Female; Glycerol; Lignans; Lung Neoplasms; Mice; Mice, Inbred ICR; Mice, Inbred SENCAR; Neoplasm Transplantation; Phytotherapy; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2000 |
Involvement of protein kinase C-regulated ceramide generation in inostamycin-induced apoptosis.
Topics: Anti-Bacterial Agents; Apoptosis; Carcinogens; Carcinoma, Small Cell; Caspase 3; Caspase Inhibitors; Caspases; Cell Division; Ceramides; Cytochrome c Group; Diacylglycerol Kinase; Enzyme Activation; Furans; Humans; Lung Neoplasms; Mitochondria; Protein Kinase C; Proteins; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2000 |
Tumorigenicity of four optically active bay-region 3,4-diol 1, 2-epoxides and other derivatives of the nitrogen heterocycle dibenz[c,h]acridine on mouse skin and in newborn mice.
Topics: Acridines; Animals; Animals, Newborn; Bay-Region, Polycyclic Aromatic Hydrocarbon; Carcinogens; Epoxy Compounds; Female; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Mice; Pregnancy; Skin; Skin Neoplasms; Stereoisomerism; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 2000 |
Nifedipine inhibits activation of transcription factor NF-kappaB.
Topics: Amlodipine; Calcium Channel Blockers; Cell Migration Inhibition; Diltiazem; Dose-Response Relationship, Drug; Epithelial Cells; Humans; Interleukin-1; Lipopolysaccharides; Luciferases; Lung Neoplasms; Lymphocyte Activation; Macrophages; NF-kappa B; Nifedipine; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Verapamil | 2000 |
Polymeric IgA binding to the human pIgR elicits intracellular signalling, but fails to stimulate pIgR-transcytosis.
Topics: Adenocarcinoma; Animals; Calcium Signaling; Cell Line; DNA, Complementary; Dogs; Enzyme Activation; Humans; Immunoglobulin A; Inositol 1,4,5-Trisphosphate; Ionomycin; Ionophores; Kidney Tubules, Proximal; Lung Neoplasms; Protein Kinase C; Protein Transport; Rabbits; Rats; Receptors, Polymeric Immunoglobulin; Recombinant Fusion Proteins; Second Messenger Systems; Signal Transduction; Species Specificity; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured; Vaccination | 2001 |
Two-stage carcinogenesis in NMRI mice: intravaginal application of 7,12-dimethylbenz[a]anthracene as initiator followed by the phorbol ester 12-O-tetradecanoylphorbol-13-acetate as promoter.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenoma; Administration, Intravaginal; Animals; Carcinogens; Carcinoma; Cocarcinogenesis; Drug Synergism; Female; Hyperplasia; Leukemia, Experimental; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Models, Animal; Neoplasms, Experimental; Organ Specificity; Ovarian Neoplasms; Papilloma; Precancerous Conditions; Sarcoma, Experimental; Specific Pathogen-Free Organisms; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Vagina; Vaginal Neoplasms | 1980 |
Mechanism of repression of squamous differentiation marker, SPRR1B, in malignant bronchial epithelial cells: role of critical TRE-sites and its transacting factors.
Topics: Animals; Base Sequence; Bronchi; Cell Line; Cornified Envelope Proline-Rich Proteins; DNA Footprinting; DNA-Binding Proteins; DNA, Neoplasm; Epithelial Cells; Fos-Related Antigen-2; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Macaca mulatta; Membrane Proteins; Molecular Motor Proteins; Promoter Regions, Genetic; Protein Biosynthesis; Proteins; Proto-Oncogene Proteins c-fos; Response Elements; Tetradecanoylphorbol Acetate; Trachea; Transcription Factor AP-1; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured; Up-Regulation | 2001 |
Different levels of TGFbeta, IL-10, IFNgamma and gelatinase A occur in experimental white and black metastases induced by bryostatin 1 or by phorbol ester-treated BL6T murine melanoma cells.
Topics: Animals; Antineoplastic Agents; Bryostatins; Interferon-gamma; Interleukin-10; L-Lactate Dehydrogenase; Lactones; Lung Neoplasms; Macrolides; Matrix Metalloproteinase 2; Melanoma; Mice; Mice, Inbred C57BL; Protein Kinase C; Reverse Transcriptase Polymerase Chain Reaction; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta | 2000 |
JNK1 and AP-1 regulate PMA-inducible squamous differentiation marker expression in Clara-like H441 cells.
Topics: Adenocarcinoma, Bronchiolo-Alveolar; Biomarkers; Carcinogens; Cell Differentiation; Cornified Envelope Proline-Rich Proteins; Gene Expression; Humans; Lung Neoplasms; MAP Kinase Kinase 1; Membrane Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; Proteins; Proto-Oncogene Proteins c-raf; ras Proteins; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription, Genetic; Tumor Cells, Cultured | 2002 |
Inhibition of both skin and lung tumorigenesis by Car-R mouse-derived cancer modifier loci.
Topics: Alleles; Animals; Animals, Outbred Strains; Carcinogenicity Tests; Carcinogens; Female; Genetic Predisposition to Disease; Inbreeding; Incidence; Lung Neoplasms; Male; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Papilloma; Phenotype; Polymerase Chain Reaction; Polymorphism, Genetic; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); ras Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate; Urethane | 2002 |
Overexpression of the human glucocorticoid receptor alpha and beta isoforms inhibits AP-1 and NF-kappaB activities hormone independently.
Topics: Animals; Chlorocebus aethiops; COS Cells; Dexamethasone; Gene Expression Regulation; Genes, Reporter; Glucocorticoids; Humans; Lung Neoplasms; NF-kappa B; Receptors, Glucocorticoid; Recombinant Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 2002 |
cis-Acting elements within CFTR 5'-flanking DNA are not sufficient to decrease gene expression in response to phorbol ester.
Topics: 5' Flanking Region; Adenocarcinoma; Animals; Colforsin; Cystic Fibrosis Transmembrane Conductance Regulator; Electrophoresis, Gel, Pulsed-Field; Gene Expression Regulation; Genes, Reporter; Humans; Luciferases; Lung Neoplasms; Promoter Regions, Genetic; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2002 |
Carcinogenicity of halogenated olefinic and aliphatic hydrocarbons in mice.
Topics: Animals; Carcinogens, Environmental; Cocarcinogenesis; Drug Evaluation, Preclinical; Female; Hydrocarbons, Halogenated; Lung Neoplasms; Male; Mice; Neoplasms, Experimental; Papilloma; Sarcoma, Experimental; Skin Neoplasms; Stomach Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1979 |
Tumorigenicity of the dihydrodiols of dibenzo(a,h)anthracene on mouse skin and in newborn mice.
Topics: Animals; Animals, Newborn; Benz(a)Anthracenes; Carcinogens; Female; Liver Neoplasms; Lung Neoplasms; Male; Mice; Neoplasms, Experimental; Pregnancy; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1979 |
Tumorigenic activity of 3-methylcholanthrene metabolites on mouse skin and in newborn mice.
Topics: Administration, Topical; Animals; Animals, Newborn; Carcinogens; Cocarcinogenesis; Drug Administration Schedule; Female; Injections, Intraperitoneal; Liver Neoplasms; Lung Neoplasms; Male; Methylcholanthrene; Mice; Neoplasms, Experimental; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1979 |
Anti-tumor-promoting activities of afromosin and soyasaponin I isolated from Wistaria brachybotrys.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Cocarcinogenesis; Female; Isoflavones; Lung Neoplasms; Mice; Mice, Inbred ICR; Oleanolic Acid; Plants, Medicinal; Saponins; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1992 |
Constitutive presence of a catalytic fragment of protein kinase C epsilon in a small cell lung carcinoma cell line.
Topics: Amino Acid Sequence; Antibodies; Binding Sites; Brain; Carcinoma, Small Cell; Cell Line; Cycloheximide; Cytosol; Humans; Immunoblotting; Isoenzymes; Kinetics; Lung Neoplasms; Molecular Sequence Data; Molecular Weight; Peptide Fragments; Peptide Mapping; Peptides; Protein Kinase C; Tetradecanoylphorbol Acetate | 1992 |
Three types of human lung tumour cell lines can be distinguished according to surface expression of endogenous urokinase and their capacity to bind exogenous urokinase.
Topics: Adenocarcinoma; Antibodies, Monoclonal; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cell Line; Cell Membrane; Humans; Immunochemistry; Kinetics; Lung Neoplasms; Mesothelioma; Protein Binding; Tetradecanoylphorbol Acetate; Urokinase-Type Plasminogen Activator | 1992 |
Increased phosphorylation of nuclear phosphoproteins in human lung-cancer cells resistant to cis-diamminedichloroplatinum (II).
Topics: Adenocarcinoma; Cell Nucleus; Cisplatin; Drug Resistance; Electrophoresis, Gel, Two-Dimensional; Ethers, Cyclic; Humans; Lung Neoplasms; Molecular Weight; Nuclear Proteins; Okadaic Acid; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured | 1992 |
A tobacco-specific N-nitrosamine or cigarette smoke condensate causes neoplastic transformation of xenotransplanted human bronchial epithelial cells.
Topics: Animals; Biomarkers, Tumor; Bronchi; Carcinogens; Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; Chemotaxis; Epithelium; ErbB Receptors; Gelatinases; Humans; Isoenzymes; Lung Neoplasms; Mice; Mice, Nude; Neoplasm Invasiveness; Nitrosamines; Pepsin A; Rats; Smoke; Smoking; Tetradecanoylphorbol Acetate; Trachea; Transforming Growth Factor alpha; Transplantation, Heterologous | 1992 |
Thrombomodulin expression in malignant pleural mesothelioma and pulmonary adenocarcinoma.
Topics: Adenocarcinoma; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Biomarkers, Tumor; Carcinoembryonic Antigen; Cell Cycle; Diagnosis, Differential; Humans; In Situ Hybridization; Lewis X Antigen; Lung; Lung Neoplasms; Mesothelioma; Receptors, Cell Surface; Receptors, Thrombin; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
12-O-tetradecanoylphorbol 13-acetate induced differentiation in human lung squamous carcinoma cells.
Topics: Antigens, Neoplasm; Carcinoma, Squamous Cell; Cell Differentiation; Cell Division; Humans; Keratins; Lung Neoplasms; Protein Precursors; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
Potent preventive action of alpha-carotene against carcinogenesis: spontaneous liver carcinogenesis and promoting stage of lung and skin carcinogenesis in mice are suppressed more effectively by alpha-carotene than by beta-carotene.
Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; beta Carotene; Carotenoids; Drug Screening Assays, Antitumor; Humans; Liver Neoplasms; Lung Neoplasms; Male; Mice; Mice, Inbred C3H; Ornithine Decarboxylase; Papilloma; Skin Neoplasms; Specific Pathogen-Free Organisms; Tetradecanoylphorbol Acetate | 1992 |
Growth control by epidermal growth factor and transforming growth factor-alpha in human lung squamous carcinoma cells.
Topics: Carcinoma, Squamous Cell; Cell Cycle; Cell Division; Cell Line; Culture Media; Epidermal Growth Factor; ErbB Receptors; Humans; Immunohistochemistry; Lung Neoplasms; Protein Precursors; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha | 1992 |
Modulation by staurosporine of phorbol-ester-induced effects on growth and protein kinase C localization in A549 human lung-carcinoma cells.
Topics: Alkaloids; Bryostatins; Cell Division; DNA; Down-Regulation; Enzyme Activation; Humans; Lactones; Lung Neoplasms; Macrolides; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate | 1992 |
Effects of TNF-alpha and phorbol ester on human surfactant protein and MnSOD gene transcription in vitro.
Topics: Adenocarcinoma; Blotting, Northern; Cell Line; Cell Nucleus; Cloning, Molecular; Dactinomycin; DNA, Neoplasm; Genes; Humans; Isoenzymes; Kinetics; Lung Neoplasms; RNA, Messenger; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Necrosis Factor-alpha | 1992 |
Regulation of protein kinase A activation and prostaglandin E2-stimulated migration of Lewis lung carcinoma clones.
Topics: Animals; Cell Movement; Cyclic AMP; Dinoprostone; Enzyme Activation; Gene Expression; Lung Neoplasms; Mice; Neoplasm Metastasis; Phosphoproteins; Protein Kinase C; Protein Kinases; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
Metastatic potential of mouse skin carcinomas produced by different protocols of chemical carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; DNA, Neoplasm; Female; gamma-Glutamyltransferase; Lung Neoplasms; Methylnitronitrosoguanidine; Mice; Neoplasm Metastasis; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1991 |
The effect of fetal calf serum on growth arrest caused by activators of protein kinase C.
Topics: alpha-Fetoproteins; Animals; Antineoplastic Agents; Blood; Bryostatins; Cattle; Cell Division; Culture Media; DNA Replication; Enzyme Activation; Epidermal Growth Factor; Humans; Kinetics; Lactones; Lung Neoplasms; Macrolides; Protein Kinase C; Tetradecanoylphorbol Acetate; Tretinoin | 1991 |
Regulation of vasopressin messenger RNA levels in the small cell lung carcinoma cell line GLC-8: interactions between glucocorticoids and second messengers.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Aldosterone; Carcinoma, Small Cell; Cell Line; Cyclic AMP; Dexamethasone; Gene Expression Regulation, Neoplastic; Humans; Hydrocortisone; Lung Neoplasms; Receptors, Glucocorticoid; RNA, Messenger; Second Messenger Systems; Tetradecanoylphorbol Acetate; Transcription, Genetic; Vasopressins | 1991 |
Transplacental and transgeneration carcinogenic effect of 7,12-dimethylbenz[a]anthracene: relationship with ras oncogene activation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Fetus; Gene Expression Regulation; Genes, ras; Lung Neoplasms; Male; Mice; Mutation; Neoplasms, Experimental; Pregnancy; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1992 |
Cytokine messenger RNA stability is enhanced in tumor cells.
Topics: Adenocarcinoma; Base Sequence; Carcinoma, Hepatocellular; Cell Line; Cytokines; Gene Expression Regulation, Neoplastic; Glioma; Globins; Granulocyte-Macrophage Colony-Stimulating Factor; Kinetics; Liver Neoplasms; Lung Neoplasms; Molecular Sequence Data; Pancreatic Neoplasms; RNA, Messenger; Tetradecanoylphorbol Acetate; Transfection | 1991 |
Sphingosine inhibits attachment of murine Lewis lung carcinoma cells to laminin and type IV collagen.
Topics: Animals; Cell Adhesion; Collagen; Extracellular Matrix Proteins; Laminin; Lung Neoplasms; Mice; Protein Kinase C; Sphingosine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
Urethan (ethyl carbamate) is an effective promoter of 7,12-dimethylbenz[a]anthracene-induced carcinogenesis in mouse skin two-stage experiments.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoma; Animals; Cocarcinogenesis; Female; Lung Neoplasms; Male; Mice; Mice, Hairless; Skin Neoplasms; Tetradecanoylphorbol Acetate; Urethane | 1991 |
Correlation between secretion pattern and metastatic potential from drug-treated 3LL tumor cell line.
Topics: Animals; Calcimycin; Female; Indomethacin; Lung Neoplasms; Mice; Mice, Inbred BALB C; Molecular Weight; Neoplasm Metastasis; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
Successful treatment of murine melanoma with bryostatin 1.
Topics: Animals; Antineoplastic Agents; Bryostatins; Cytotoxicity, Immunologic; Female; Killer Cells, Lymphokine-Activated; Lactones; Lung Neoplasms; Macrolides; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Spleen; Tetradecanoylphorbol Acetate | 1991 |
Novel non-tumorigenic cell variants showing potentially different susceptibility to v-src-induced metastasis.
Topics: Animals; Cell Transformation, Viral; Drug Resistance; Female; Genes, ras; Lung Neoplasms; Mice; Mice, Inbred BALB C; Oncogene Protein pp60(v-src); Tetradecanoylphorbol Acetate | 1990 |
Cross-resistance to tumour promoters in human cancer cell lines resistant to adriamycin or cisplatin.
Topics: Cell Division; Cell Line; Chemical Phenomena; Chemistry; Cisplatin; Cross Reactions; Doxorubicin; Drug Resistance; Ethers, Cyclic; Humans; Leukemia, Myeloid; Lung Neoplasms; Lyngbya Toxins; Okadaic Acid; Tetradecanoylphorbol Acetate | 1990 |
Phorbol ester inhibits surfactant protein SP-A and SP-B expression.
Topics: Adenocarcinoma; Cell Line; Dactinomycin; Enzyme-Linked Immunosorbent Assay; Glycoproteins; Humans; Kinetics; L-Lactate Dehydrogenase; Lung Neoplasms; Methionine; Phorbol 12,13-Dibutyrate; Protein Binding; Proteolipids; Pulmonary Surfactant-Associated Protein A; Pulmonary Surfactant-Associated Proteins; Pulmonary Surfactants; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1990 |
The coregulation of secretion and cytoplasmic ribonucleic acid of chromogranin-A and calcitonin by phorbol ester in cells that produce both substances.
Topics: Calcitonin; Cell Line; Chromogranin A; Chromogranins; Dose-Response Relationship, Drug; Humans; Lung Neoplasms; Nerve Tissue Proteins; Nucleic Acid Hybridization; Phorbol Esters; Phorbols; RNA; Tetradecanoylphorbol Acetate; Thyroid Neoplasms; Tumor Cells, Cultured | 1988 |
Bidirectional control of membrane expression and/or activation of the tumor cell IRGpIIb/IIIa receptor and tumor cell adhesion by lipoxygenase products of arachidonic acid and linoleic acid.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Animals; Antibodies; Antibodies, Monoclonal; Antigen-Antibody Complex; Arachidonic Acids; Cell Adhesion; Cell Membrane; Collagen; Endothelium, Vascular; Flow Cytometry; Fluorescent Antibody Technique; Hydroxyeicosatetraenoic Acids; Isomerism; Linoleic Acid; Linoleic Acids; Lipoxygenase; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL; Platelet Membrane Glycoproteins; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1989 |
Lung cancer cells often express high levels of protein kinase C activity.
Topics: Animals; Calcium; Chromatography; Female; Humans; Lung Neoplasms; Mice; Pancreatic Neoplasms; Phosphatidylserines; Protein Kinase C; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Tongue Neoplasms; Tumor Cells, Cultured; Vulvar Neoplasms | 1989 |
Rapid phosphorylation of the L-myc protein induced by phorbol ester tumor promoters and serum.
Topics: Antibodies, Monoclonal; Blood Physiological Phenomena; Carcinoma, Small Cell; Enzyme Activation; Humans; Lung Neoplasms; Neoplasm Proteins; Phosphorylation; Protein Kinase C; Protein Processing, Post-Translational; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myc; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
Membrane-bound protein kinase C modulates receptor affinity and chemotactic responsiveness of Lewis lung carcinoma sublines to an elastin-derived peptide.
Topics: Alkaloids; Amino Acid Sequence; Animals; Cell Line; Cell Membrane; Chemotaxis; Kinetics; Lung Neoplasms; Mice; Mice, Inbred C57BL; Oligopeptides; Protein Kinase C; Receptors, Cell Surface; Staurosporine; Tetradecanoylphorbol Acetate | 1989 |
Protein kinase-C-induced down-regulation of calcitonin receptors and calcitonin-activated adenylate cyclase in T47D and BEN cells.
Topics: Adenylyl Cyclases; Breast Neoplasms; Calcitonin; Cell Line; Colforsin; Dinitrophenols; Down-Regulation; Enzyme Activation; Female; Humans; Kinetics; Lung Neoplasms; Protein Kinase C; Receptors, Calcitonin; Receptors, Cell Surface; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
Increased cytosolic pH in multidrug-resistant human lung tumor cells: effect of verapamil.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Carrier Proteins; Cytosol; Doxorubicin; Drug Resistance; Humans; Hydrogen-Ion Concentration; Lung Neoplasms; Membrane Glycoproteins; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Verapamil | 1989 |
Modulatory effects of 5-azacytidine, phorbol ester, and retinoic acid on the malignant phenotype of human lung cancer cells.
Topics: Animals; Azacitidine; Carcinoma, Small Cell; Cell Line; Clone Cells; Humans; Lung Neoplasms; Mice; Mice, Nude; Mitosis; Neoplasm Transplantation; Phenotype; Phorbols; Tetradecanoylphorbol Acetate; Tretinoin | 1985 |
Experimental analysis of the effects of cyclosporine on the induction and growth of epithelial tumors.
Topics: Adenoma; Administration, Oral; Administration, Topical; Animals; Carcinoma, Squamous Cell; Cell Division; Cyclosporins; Lung Neoplasms; Male; Mice; Skin Neoplasms; Tetradecanoylphorbol Acetate; Urethane | 1989 |
Comparison of effects of bryostatins 1 and 2 and 12-O-tetradecanoylphorbol-13-acetate on protein kinase C activity in A549 human lung carcinoma cells.
Topics: Antineoplastic Agents; Bryostatins; Cell Line; Cytosol; Humans; Kinetics; Lactones; Lung Neoplasms; Macrolides; Membranes; Protein Kinase C; Tetradecanoylphorbol Acetate | 1989 |
Sterically hindered analogues of diacylglycerols. Synthesis, binding to the phorbol ester receptor and metabolism in A549 human lung carcinoma cells.
Topics: Caenorhabditis elegans Proteins; Carrier Proteins; Diglycerides; Glycerides; Humans; Lung Neoplasms; Protein Kinase C; Receptors, Drug; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
Activation of the second promoter of the transforming growth factor-beta 1 gene by transforming growth factor-beta 1 and phorbol ester occurs through the same target sequences.
Topics: Animals; Base Sequence; Cell Line; Cells, Cultured; Deoxyribonuclease I; Fibrosarcoma; Gene Expression Regulation; Genes; Homeostasis; Humans; Lung Neoplasms; Mice; Molecular Sequence Data; Mutation; Plasmids; Promoter Regions, Genetic; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Transforming Growth Factors | 1989 |
Effects of activators of protein kinase C, including bryostatins 1 and 2, on the growth of A549 human lung carcinoma cells.
Topics: Animals; Bryostatins; Cell Division; Diterpenes; DNA Replication; Enzyme Activation; Lactones; Lung Neoplasms; Macrolides; Protein Kinase C; Terpenes; Tetradecanoylphorbol Acetate; Time Factors | 1989 |
Effect of recombinant monokines, lymphokines, and other agents on clonal proliferation of human lung cancer cell lines.
Topics: Calcitriol; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cell Division; Cell Line; Clone Cells; Colony-Stimulating Factors; Dimethyl Sulfoxide; Drug Synergism; Humans; Interleukin-1; Lung Neoplasms; Lymphokines; Monokines; Proteins; Receptors, Cell Surface; Receptors, Tumor Necrosis Factor; Recombinant Proteins; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Stem Cell Assay | 1987 |
Inhibition of the prenatal dimethylbenz[a]anthracene-induced tumour initiation in mice by prior administration of 7,8-benzoflavone.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoma; Administration, Oral; Animals; Benzoflavones; Cocarcinogenesis; Female; Flavonoids; Lung Neoplasms; Mice; Neoplasms, Experimental; Papilloma; Pregnancy; Prenatal Exposure Delayed Effects; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1986 |
Persistence of carcinogenic effect in intact progeny of mice treated transplacentally with 7,12-dimethylbenz[a]anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Fetus; Lung Neoplasms; Male; Mammary Neoplasms, Experimental; Mice; Neoplasms, Experimental; Pregnancy; Sex Factors; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1987 |
Tumor promoter-induced membrane-bound protein kinase C regulates hematogenous metastasis.
Topics: Animals; Carcinogens; Cell Line; Cell Membrane; Cytosol; Enzyme Induction; Kinetics; Lung Neoplasms; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Tetradecanoylphorbol Acetate | 1988 |
Effect of two inducers of cellular differentiation on the glutathione status of human HL-60 promyelocytic leukaemia and A549 lung carcinoma cells.
Topics: Animals; Carcinoma; Cell Differentiation; Cell Line; Dimethyl Sulfoxide; Formamides; Glutathione; Humans; Leukemia, Myeloid, Acute; Lung Neoplasms; Mice; Neoplasms, Experimental; Tetradecanoylphorbol Acetate | 1987 |
Interleukin 1 production by human lung tissue. II. Inhibition by anti-inflammatory steroids.
Topics: Anti-Inflammatory Agents; Cell Adhesion; Cells, Cultured; Depression, Chemical; Endothelium, Vascular; Gonadal Steroid Hormones; Humans; Interleukin-1; Lipopolysaccharides; Lung; Lung Neoplasms; Neutrophils; Steroids; Tetradecanoylphorbol Acetate | 1987 |
Characterization of the growth inhibition induced by tumor-promoting phorbol esters and of their receptor binding in A549 human lung carcinoma cells.
Topics: Caenorhabditis elegans Proteins; Carcinoma; Carrier Proteins; Cell Division; Cells, Cultured; Humans; Lung Neoplasms; Male; Middle Aged; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Kinase C; Receptors, Drug; Receptors, Immunologic; Tetradecanoylphorbol Acetate; Tritium; Type C Phospholipases | 1985 |
Effects of 12-O-tetradecanoylphorbol-13-acetate on adhesiveness and lung-colonizing ability of Lewis lung carcinoma cells.
Topics: Animals; Cell Adhesion; Diglycerides; Diterpenes; Lung Neoplasms; Male; Mice; Mitogens; Neoplasm Metastasis; Phorbol Esters; Phorbols; Protein Kinases; Structure-Activity Relationship; Terpenes; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1986 |
Oxidative properties of 12-O-tetradecanoylphorbol-13-acetate-stimulated human blood monomorphonuclear leukocytes and their toxicity against a human lung carcinoma cell line.
Topics: Cell Line; Cytotoxicity, Immunologic; Free Radicals; Glutathione; Humans; Killer Cells, Natural; Leukocytes; Lung Neoplasms; Male; Middle Aged; Oxidation-Reduction; Phorbols; Sulfhydryl Compounds; Tetradecanoylphorbol Acetate; Tretinoin | 1985 |
Reactive oxygen dependent activation of polycyclic hydrocarbons by phorbol ester-stimulated human polymorphonuclear leukocytes.
Topics: Benzopyrenes; Biotransformation; Carcinogens; Dihydroxydihydrobenzopyrenes; DNA; Humans; Luminescent Measurements; Lung Neoplasms; Mutagenicity Tests; Neutrophils; Oxidation-Reduction; Oxygen; Phorbols; Polycyclic Compounds; Superoxide Dismutase; Tetradecanoylphorbol Acetate | 1985 |