tetradecanoylphorbol acetate has been researched along with B16 Melanoma in 54 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 6 (11.11) | 18.7374 |
1990's | 25 (46.30) | 18.2507 |
2000's | 10 (18.52) | 29.6817 |
2010's | 12 (22.22) | 24.3611 |
2020's | 1 (1.85) | 2.80 |
Authors | Studies |
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Liu, LG; Tan, RX | 1 |
Athar, M; Elmets, CA; Nasti, TH; Sherwani, MA; Timares, L; Yusuf, N | 1 |
Callejas-Valera, JL; Cimas, FJ; Fernandez-Aroca, DM; Garcia-Gil, E; García-Olmo, DC; Gutkind, JS; Hernández-Losa, J; Marcos, P; Melgar-Rojas, P; Ortega-Muelas, M; Pascual-Serra, R; Ramón Y Cajal, S; Roche, O; Ruiz-Hidalgo, MJ; Sanchez-Prieto, R | 1 |
Bang, S; Chang, SE; Kim, I; Kim, J; Kim, YH; Song, Y; Yoo, H | 1 |
Romanchikova, N; Trapencieris, P; Turks, M; Zemītis, J | 1 |
Bouvard, C; Bussolino, F; Chiaverina, G; di Blasio, L; Gagliardi, PA; Helley, D; Jain, RK; Primo, L; Puliafito, A; Seano, G; Serini, G; Sessa, R; Sorokin, L; Tarone, G | 1 |
Akihisa, M; Akihisa, T; Ebina, K; Feng, F; Kurita, M; Masters, ET; Shimizu, N; Tokuda, H; Ukiya, M; Yasukawa, K; Zhang, J | 1 |
Im, M; Kim, A; Ma, JY | 1 |
Barison, A; Iacomini, M; Jacomasso, T; Riter, DS; Santana-Filho, AP; Sassaki, GL; Winnischofer, SM | 1 |
Estrada-Bernal, A; Gatlin, JC; Pfenninger, KH; Sunpaweravong, S | 1 |
Gude, RP; Jain, M; Ratheesh, A | 1 |
Ambudkar, SV; Garfield, SH; Lee, A; Li, L; Maloney, DJ; Shukla, S; Yuspa, SH | 1 |
Leung, LK; Yi Lau, GT | 1 |
Akihisa, T; Banno, N; Fujita, Y; Fukatsu, M; Kikuchi, T; Takagi, M; Takahashi, A; Tokuda, H; Watanabe, K; Yasukawa, K | 1 |
Holmen, SL; McKinney, AJ | 1 |
Hearing, VJ; Ichihashi, M; Kageyama, A; Nakamura, S; Nishigori, C; Oka, M; Okada, T; Saito, N; Ueyama, T | 1 |
Bastian, BC; Curtin, JA; Dumaz, N; Hayward, R; Hedley, D; Marais, R; Martin, J; Ogilvie, L; Springer, C | 1 |
Cotter, MA; Florell, SR; Grossman, D; Hanks, AN; Liu, T; Robinette, K; Thomas, J | 1 |
Carsberg, CJ; Friedmann, PS; Warenius, HM | 1 |
Butovich, I; Hannun, YA; Honn, KV; Khan, WA; Liu, B; Lundy, S; Taylor, JD; Timar, J | 1 |
Ballotti, R; Durand-Clément, M; Englaro, W; Lallemand, D; Ortonne, JP; Rezzonico, R | 1 |
Hart, IR; Miller, N; Vile, RG | 1 |
Donatien, PD; Hunt, G; Thody, AJ; Todd, C | 1 |
Huijzer, JC; McFarland, M; Meadows, GG; Niles, RM | 1 |
Fujikawa-Yamamoto, K; Odashima, S; Tanino, M; Teraoka, K; Yamagishi, H; Zong, Z | 1 |
Fenner, MH; Isselbacher, KJ; Jain, RK; Munn, LL; Shioda, T | 1 |
Ballotti, R; Bertolotto, C; Brunet, A; Buscà, R; Englaro, W; Ortonne, JP; Pagès, G | 1 |
Ballotti, R; Bertolotto, C; Bille, K; Ortonne, JP | 1 |
Comolli, R; La Porta, CA | 1 |
Comolli, R; Di Dio, A; La Porta, CA; Porro, D | 1 |
Ballestrem, C; Hinz, B; Imhof, BA; Wehrle-Haller, B | 1 |
Beyer, C; Blessing, M; Breuhahn, K; Mann, A; Ozbek, S; Rose-John, S; Rosenau, A; Schirmacher, P; Wilhelmi, A | 1 |
Amoscato, AA; Hunter, OC; Kalinski, P; Kanto, T; Lotze, MT | 1 |
Bastida, CM; Garcija-Borron, JC; Martijnez-Esparza, M; Penafiel, R; Sanchez Mas, J; Solano, F | 1 |
Bleehen, SS; Buffery, J; Dobson, J; Hill, SE; Mac Neil, S | 1 |
Beaumont, J; Blackburn, GM; Brown, J; Doughty, S; Mac Neil, S; Wagner, M; Wowk, I | 1 |
Brooks, G; Goss, MW; Hart, IR | 1 |
Dougherty, N; Larue, L; Mintz, B; Porter, S | 1 |
Fuks, BB; Klaamas, KV; Rakhmilevich, AL | 1 |
Busam, KJ; Roberts, AB; Sporn, MB | 1 |
Bennett, DC; Devlin, LM; Greetham, J; Wakeling, WF | 1 |
DiGregorio, FM; Hashimoto, K; Ishihara, M; Pietruk, T; Richards, J; Setoyama, M; Zarbo, RJ | 1 |
Fuller, BB; Hoganson, GE; Niekrasz, I | 1 |
Ito, A; Mishima, Y; Takeuchi, T; Tanaka, C | 1 |
Rieber, M; Rieber, MS | 1 |
Esa, AH; Hess, AD; Laulis, MK; May, S; Pettit, GR; Schuchter, LM | 1 |
Brooks, G; Dooley, TP; Goss, MW; Hart, IR; Wilson, RE | 1 |
Friedmann, PS; Matthews, JN; Wren, FE | 1 |
Kuklinska, E; Moellmann, G; Slominski, A | 1 |
Conn, KG; Knudsen, KA | 1 |
Dooley, TP; Hart, IR; Jones, NC; Wilson, RE | 1 |
Barsky, SH; Gopalakrishna, R | 1 |
Hanson, MB; Lioubin, MN; Marquardt, H; Shoyab, M; Todaro, GJ; Zarling, JM | 1 |
Kodama, M; Saitô, H; Sugimoto, Y; Tabeta, R | 1 |
3 review(s) available for tetradecanoylphorbol acetate and B16 Melanoma
Article | Year |
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Animal models of melanoma: a somatic cell gene delivery mouse model allows rapid evaluation of genes implicated in human melanoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Avian Leukosis Virus; Avian Proteins; Cell Line, Tumor; Disease Models, Animal; Gene Transfer Techniques; Genetic Vectors; Humans; Melanocytes; Melanoma; Melanoma, Experimental; Mice; Mice, Transgenic; Neoplasm Transplantation; Receptors, Virus; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transgenes | 2011 |
Human melanocytes express functional melanocyte-stimulating hormone receptors.
Topics: Animals; Cells, Cultured; Cholera Toxin; Gene Expression; Humans; Interferon-gamma; Melanins; Melanocyte-Stimulating Hormones; Melanocytes; Melanoma, Experimental; Mice; Receptors, Pituitary Hormone; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Ultraviolet Rays | 1993 |
Intracellular signalling in the control of melanogenesis.
Topics: Animals; Calcium; Calmodulin; Cyclic AMP; Diglycerides; Gene Expression Regulation, Neoplastic; Melanins; Melanocyte-Stimulating Hormones; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mice, Nude; Naphthalenes; Protein Kinase C; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
51 other study(ies) available for tetradecanoylphorbol acetate and B16 Melanoma
Article | Year |
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New jatrophane diterpenoid esters from Euphorbia turczaninowii.
Topics: Animals; Antineoplastic Agents, Phytogenic; Chromatography, Thin Layer; Crystallography, X-Ray; Diterpenes; Drugs, Chinese Herbal; Ear; Euphorbiaceae; Magnetic Resonance Spectroscopy; Melanoma, Experimental; Mice; Molecular Conformation; Molecular Structure; Plants, Medicinal; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Tumor Cells, Cultured | 2001 |
Regulatory T Cells Play an Important Role in the Prevention of Murine Melanocytic Nevi and Melanomas.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; CD4 Antigens; CD8 Antigens; Female; Humans; Immune Tolerance; Male; Melanoma, Experimental; Mice; Mice, Knockout; Nevus, Pigmented; Skin; Skin Neoplasms; T-Lymphocytes, Regulatory; Tetradecanoylphorbol Acetate | 2021 |
E1a is an exogenous in vivo tumour suppressor.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenovirus E1A Proteins; Animals; Cell Proliferation; Cell Transformation, Neoplastic; Female; HCT116 Cells; Humans; Melanoma, Experimental; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Nude; Mice, Transgenic; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Transfection; Tumor Burden; Tumor Suppressor Proteins | 2017 |
L-765,314 Suppresses Melanin Synthesis by Regulating Tyrosinase Activity.
Topics: Animals; Bleaching Agents; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression Regulation; High-Throughput Screening Assays; Melanins; Melanoma, Experimental; Mice; Monophenol Monooxygenase; Prazosin; Protein Kinase C; Signal Transduction; Small Molecule Libraries; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2019 |
A novel matrix metalloproteinase-2 inhibitor triazolylmethyl aziridine reduces melanoma cell invasion, angiogenesis and targets ERK1/2 phosphorylation.
Topics: Animals; Aziridines; Cell Line, Tumor; Cell Movement; Collagen; Diffusion Chambers, Culture; Drug Combinations; Gene Expression Regulation, Neoplastic; Human Umbilical Vein Endothelial Cells; Humans; Laminin; Matrix Metalloproteinase 2; Matrix Metalloproteinase Inhibitors; Melanoma, Experimental; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neovascularization, Pathologic; Phosphorylation; Proteoglycans; Signal Transduction; Tetradecanoylphorbol Acetate; Triazoles; Vascular Endothelial Growth Factor A | 2014 |
Endothelial podosome rosettes regulate vascular branching in tumour angiogenesis.
Topics: Animals; Basement Membrane; Cell Line, Tumor; Cell Membrane Structures; Cells, Cultured; Endothelial Cells; Green Fluorescent Proteins; HEK293 Cells; HeLa Cells; Humans; Integrin alpha6beta1; Laminin; Lung Neoplasms; Male; Matrix Metalloproteinase 14; Melanoma, Experimental; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Confocal; Microscopy, Fluorescence; Neoplasms; Neovascularization, Pathologic; RNA Interference; Tetradecanoylphorbol Acetate; Vascular Endothelial Growth Factor A | 2014 |
Melanogenesis-inhibitory activity and cancer chemopreventive effect of glucosylcucurbic acid from shea (Vitellaria paradoxa) kernels.
Topics: alpha-MSH; Animals; Anticarcinogenic Agents; Antigens, Viral; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Glucosides; Humans; Melanins; Melanoma, Experimental; Mice, Inbred Strains; Molecular Structure; Monophenol Monooxygenase; Oxidoreductases; Oxylipins; Plant Extracts; Sapotaceae; Seeds; Skin Neoplasms; Tetradecanoylphorbol Acetate; Xenograft Model Antitumor Assays | 2015 |
Ethanol extract of baked Gardeniae Fructus exhibits in vitro and in vivo anti-metastatic and anti-angiogenic activities in malignant cancer cells: Role of suppression of the NF-κB and HIF-1α pathways.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Gardenia; Human Umbilical Vein Endothelial Cells; Hypoxia-Inducible Factor 1, alpha Subunit; Lung Neoplasms; Matrix Metalloproteinase 13; Matrix Metalloproteinase 9; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Neovascularization, Pathologic; Plant Extracts; Tetradecanoylphorbol Acetate; Transcription Factor RelA | 2016 |
NMR metabolic fingerprints of murine melanocyte and melanoma cell lines: application to biomarker discovery.
Topics: Animals; Biomarkers; Cell Line, Tumor; Gene Expression Regulation; Magnetic Resonance Spectroscopy; Melanocytes; Melanoma, Experimental; Metabolome; Metabolomics; Mice; Multivariate Analysis; Principal Component Analysis; Tetradecanoylphorbol Acetate | 2017 |
Dynamic adhesions and MARCKS in melanoma cells.
Topics: Animals; Cell Adhesion; Cell Line, Tumor; Cell Movement; Humans; Integrin alpha3; Intercellular Junctions; Intracellular Signaling Peptides and Proteins; Isoenzymes; Melanoma; Melanoma, Experimental; Membrane Proteins; Mice; Myristoylated Alanine-Rich C Kinase Substrate; Paxillin; Protein Kinase C; Rats; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Vinculin | 2009 |
Pentoxifylline inhibits integrin-mediated adherence of 12(S)-HETE and TNFalpha-activated B16F10 cells to fibronectin and endothelial cells.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Animals; Antineoplastic Agents; Cell Adhesion; Cell Line, Tumor; Endothelial Cells; Fibronectins; Integrins; Melanoma, Experimental; Mice; Pentoxifylline; Phosphodiesterase Inhibitors; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2010 |
The skin cancer chemotherapeutic agent ingenol-3-angelate (PEP005) is a substrate for the epidermal multidrug transporter (ABCB1) and targets tumor vasculature.
Topics: Administration, Topical; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Squamous Cell; Cell Line, Tumor; Diterpenes; Drug Eruptions; Enzyme Activation; Humans; Keratinocytes; Melanoma, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; Neovascularization, Pathologic; Protein Binding; Protein Kinase C; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2010 |
The dietary flavonoid apigenin blocks phorbol 12-myristate 13-acetate-induced COX-2 transcriptional activity in breast cell lines.
Topics: Animals; Apigenin; Apoptosis; Blotting, Western; Breast Neoplasms; Caspase 3; Cell Division; Cell Line, Tumor; Cyclooxygenase 2; Dinoprostone; Electrophoretic Mobility Shift Assay; Extracellular Signal-Regulated MAP Kinases; Female; G2 Phase; Gene Expression Regulation, Enzymologic; Humans; Luciferases; Melanoma, Experimental; Mice; Protein Kinases; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcriptional Activation | 2010 |
The melanogenesis-inhibitory, anti-inflammatory, and chemopreventive effects of limonoids in n-hexane extract of Azadirachta indica A. Juss. (neem) seeds.
Topics: Animals; Anti-Inflammatory Agents; Antigens, Viral; Azadirachta; Cell Death; Chemoprevention; Fatty Acids; Hexanes; Limonins; Magnetic Resonance Spectroscopy; Melanins; Melanoma, Experimental; Mice; Plant Extracts; Seeds; Tetradecanoylphorbol Acetate | 2011 |
Down-regulation of melanogenesis by phospholipase D2 through ubiquitin proteasome-mediated degradation of tyrosinase.
Topics: 1-Butanol; alpha-MSH; Animals; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Down-Regulation; Enzyme Activation; Kidney; Leupeptins; Lung; Melanins; Melanoma, Experimental; Mice; Monophenol Monooxygenase; Multienzyme Complexes; Phospholipase D; Proteasome Endopeptidase Complex; Protein Kinase C; Tetradecanoylphorbol Acetate; Ubiquitin | 2004 |
In melanoma, RAS mutations are accompanied by switching signaling from BRAF to CRAF and disrupted cyclic AMP signaling.
Topics: alpha-MSH; Animals; Cell Line, Tumor; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Extracellular Signal-Regulated MAP Kinases; Female; Genes, ras; Humans; Melanocytes; Melanoma; Melanoma, Experimental; Mice; Mice, Nude; Mutation; Neoplasm Proteins; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-raf; Signal Transduction; Tetradecanoylphorbol Acetate | 2006 |
Melanocyte expression of survivin promotes development and metastasis of UV-induced melanoma in HGF-transgenic mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Cell Growth Processes; Female; Hepatocyte Growth Factor; Inhibitor of Apoptosis Proteins; Melanocytes; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Transgenic; Microtubule-Associated Proteins; Nevus, Pigmented; Repressor Proteins; Skin Pigmentation; Survivin; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 2007 |
Ultraviolet radiation-induced melanogenesis in human melanocytes. Effects of modulating protein kinase C.
Topics: 1-Methyl-3-isobutylxanthine; 3T3 Cells; Animals; Diglycerides; Enzyme Induction; Humans; Indoles; Intracellular Signaling Peptides and Proteins; Isoenzymes; Melanins; Melanocytes; Melanoma; Melanoma, Experimental; Membrane Proteins; Mice; Myristoylated Alanine-Rich C Kinase Substrate; Neoplasm Proteins; Phosphorylation; Protein Kinase C; Protein Processing, Post-Translational; Proteins; Signal Transduction; Skin Neoplasms; Taurodeoxycholic Acid; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 1994 |
12(S)-hydroxyeicosatetraenoic acid and 13(S)-hydroxyoctadecadienoic acid regulation of protein kinase C-alpha in melanoma cells: role of receptor-mediated hydrolysis of inositol phospholipids.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Animals; Binding Sites; Brain; Cell Adhesion; Cell Line; Cell Membrane; Cytosol; Diglycerides; Fibronectins; Hydrolysis; Hydroxyeicosatetraenoic Acids; Inositol 1,4,5-Trisphosphate; Isoenzymes; Kinetics; Linoleic Acids; Melanoma, Experimental; Mice; Pertussis Toxin; Phosphatidylinositols; Protein Kinase C; Receptors, Cell Surface; Recombinant Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1995 |
Mitogen-activated protein kinase pathway and AP-1 are activated during cAMP-induced melanogenesis in B-16 melanoma cells.
Topics: 1-Methyl-3-isobutylxanthine; Affinity Labels; alpha-MSH; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Nucleus; Cyclic AMP; Enzyme Activation; Gene Expression; MAP Kinase Kinase Kinase 1; Melanins; Melanoma, Experimental; Mice; Microscopy, Confocal; Mitogen-Activated Protein Kinase Kinases; Monophenol Monooxygenase; Phosphodiesterase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-jun; Proto-Oncogene Proteins c-raf; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription Factor AP-1 | 1995 |
Effects of modulators of tyrosinase activity on expression of murine interleukin-2 cDNA driven by the tyrosinase promoter.
Topics: 3T3 Cells; Aminophylline; Animals; Consensus Sequence; DNA, Complementary; Dose-Response Relationship, Drug; Enzyme Activation; Gene Expression Regulation, Neoplastic; Genes, Reporter; Interleukin-2; Melanoma, Experimental; Mice; Mice, Inbred BALB C; Monophenol Monooxygenase; Promoter Regions, Genetic; Tetradecanoylphorbol Acetate; Theophylline; Transfection; Tretinoin; Tumor Cells, Cultured; Up-Regulation | 1995 |
Phorbol 12-myristate 13-acetate enhances nm23 gene expression in murine melanocytes but not in syngeneic B16-BL6 melanoma variants.
Topics: Animals; Cell Division; Cell Membrane; Cytosol; Female; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Melanocytes; Melanoma, Experimental; Mice; Monomeric GTP-Binding Proteins; Neoplasm Metastasis; NM23 Nucleoside Diphosphate Kinases; Nucleoside-Diphosphate Kinase; Phenylalanine; Protein Kinase C; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Transcription Factors; Tumor Cells, Cultured; Tyrosine | 1996 |
Saikosaponin b2-induced apoptosis of cultured B16 melanoma cell line through down-regulation of PKC activity.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Division; Cell Line; Cell Nucleus; DNA, Neoplasm; Dose-Response Relationship, Drug; Flow Cytometry; G1 Phase; Kinetics; Melanoma, Experimental; Mice; Oleanolic Acid; Protein Kinase C; Sapogenins; Saponins; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1996 |
Early events of metastasis in the microcirculation involve changes in gene expression of cancer cells. Tracking mRNA levels of metastasizing cancer cells in the chick embryo chorioallantoic membrane.
Topics: Actins; Allantois; Animals; Chick Embryo; Chorion; Gene Expression Regulation, Neoplastic; Genes, fos; Melanoma, Experimental; Mice; Microcirculation; Microscopy, Fluorescence; Microscopy, Video; Neoplasm Metastasis; Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Tetrahydrofolate Dehydrogenase; Tumor Cells, Cultured | 1997 |
Inhibition of the mitogen-activated protein kinase pathway triggers B16 melanoma cell differentiation.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Differentiation; Colforsin; Cyclic AMP; Enzyme Inhibitors; Flavonoids; Luciferases; Melanoma, Experimental; Mice; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Monophenol Monooxygenase; Protein Kinase Inhibitors; Protein Kinases; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1998 |
In B16 melanoma cells, the inhibition of melanogenesis by TPA results from PKC activation and diminution of microphthalmia binding to the M-box of the tyrosinase promoter.
Topics: Animals; Binding Sites; Carcinogens; Colforsin; DNA-Binding Proteins; Enzyme Activation; Helix-Loop-Helix Motifs; Isoenzymes; Melanoma, Experimental; Mice; Microphthalmia-Associated Transcription Factor; Monophenol Monooxygenase; Promoter Regions, Genetic; Protein Kinase C; Protein Kinase C-alpha; Tetradecanoylphorbol Acetate; Transcription Factors; Transcriptional Activation | 1998 |
Angiogenic capacity and lung-colonizing potential in vivo is increased in weakly metastatic B16F1 cells and decreased in highly metastatic BL6 cells by phorbol esters.
Topics: Animals; Carcinogens; Endothelial Growth Factors; Fibroblast Growth Factors; Lung Neoplasms; Lymphokines; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Neoplasm Transplantation; Neovascularization, Pathologic; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1998 |
Overexpression of novel protein kinase C delta in BL6 murine melanoma cells inhibits the proliferative capacity in vitro but enhances the metastatic potential in vivo.
Topics: Adjuvants, Immunologic; Animals; Antineoplastic Agents; Bryostatins; Cell Cycle; Cell Division; Cyclic AMP; Isoenzymes; Lactones; Macrolides; Melanins; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Neoplasm Proteins; Protein Isoforms; Protein Kinase C; Protein Kinase C-delta; Recombinant Fusion Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 2000 |
Actin-dependent lamellipodia formation and microtubule-dependent tail retraction control-directed cell migration.
Topics: Actins; Animals; Cell Line; Cell Movement; Cytoplasm; Green Fluorescent Proteins; Luminescent Proteins; Melanocytes; Melanoma, Experimental; Mice; Microtubules; Nocodazole; Paclitaxel; Proto-Oncogene Proteins c-kit; rac GTP-Binding Proteins; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 2000 |
Up- and down-regulation of granulocyte/macrophage-colony stimulating factor activity in murine skin increase susceptibility to skin carcinogenesis by independent mechanisms.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Down-Regulation; Granulocyte-Macrophage Colony-Stimulating Factor; Keratin-10; Keratins; Melanoma, Experimental; Mice; Mice, Transgenic; Neoplasm Transplantation; Phenotype; Skin; Skin Neoplasms; Skin Physiological Phenomena; Tetradecanoylphorbol Acetate; Transgenes; Up-Regulation | 2001 |
Ceramide mediates tumor-induced dendritic cell apoptosis.
Topics: Animals; Apoptosis; bcl-X Protein; Caspases; Cells, Cultured; Ceramides; Culture Media, Conditioned; Dendritic Cells; Lymphocyte Culture Test, Mixed; Melanoma, Experimental; Mice; Mice, Inbred BALB C; Neoplasms; NF-kappa B; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Receptors, Interleukin; Receptors, Interleukin-12; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Escape | 2001 |
Regulation of ornithine decarboxylase in B16 mouse melanoma cells: synergistic activation of melanogenesis by alphaMSH and ornithine decarboxylase inhibition.
Topics: alpha-MSH; Animals; Cell Line; Eflornithine; Enzyme Activation; Gene Expression Regulation, Enzymologic; Melanins; Melanoma, Experimental; Mice; Monophenol Monooxygenase; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Up-Regulation | 2002 |
Intracellular regulation of cell adhesion to extracellular matrix components in murine B16 melanoma cells.
Topics: Animals; Calmodulin; Cell Adhesion; Clone Cells; Collagen; Cyclic AMP; Dideoxyadenosine; Extracellular Matrix; Fibronectins; Kinetics; Laminin; Melanocyte-Stimulating Hormones; Melanoma, Experimental; Mice; Naphthalenes; Neoplasm Metastasis; Protein Kinase C; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Time Factors | 1992 |
Differential induction of 12-O-tetradecanoylphorbol-13-acetate sequence gene expression in murine melanocytes and melanoma cells.
Topics: 3T3 Cells; Animals; Blotting, Northern; Bucladesine; Cell Line, Transformed; Cells, Cultured; Cycloheximide; Gene Expression; Genes, fos; Melanocytes; Melanoma, Experimental; Mice; Molecular Weight; Phorbol 12,13-Dibutyrate; RNA; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 1992 |
Spontaneous malignant transformation of melanocytes explanted from Wf/Wf mice with a Kit kinase-domain mutation.
Topics: Animals; Base Sequence; Cell Death; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Genes, Dominant; Genotype; Melanocytes; Melanoma, Experimental; Mice; Mice, Inbred C3H; Mice, Mutant Strains; Molecular Sequence Data; Mutation; Oligodeoxyribonucleotides; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-kit; Proto-Oncogenes; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1992 |
[Study of the possibility to abolish the action of immunosuppressive factors of tumor cells].
Topics: Acetylmuramyl-Alanyl-Isoglutamine; Animals; Aprotinin; Concanavalin A; Immune Tolerance; Interleukin-2; Ionomycin; Lipopolysaccharides; Lymphocyte Activation; Mast-Cell Sarcoma; Melanoma, Experimental; Mice; Sarcoma, Experimental; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
Inhibition of mitogen-induced c-fos expression in melanoma cells by retinoic acid involves the serum response element.
Topics: Animals; Cell Division; DNA-Binding Proteins; Down-Regulation; Gene Expression Regulation; Genes, fos; Genes, jun; Melanoma, Experimental; Mice; Mitogens; Nuclear Proteins; Plasmids; Precipitin Tests; Promoter Regions, Genetic; Regulatory Sequences, Nucleic Acid; Serum Response Factor; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tretinoin; Tumor Cells, Cultured | 1992 |
Suppression of properties associated with malignancy in murine melanoma-melanocyte hybrid cells.
Topics: Animals; Cell Division; Clone Cells; Culture Media; Genes, Tumor Suppressor; Hybrid Cells; Melanocytes; Melanoma, Experimental; Mice; Pigmentation; Sepharose; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
Monoclonal anti-melanoma antibodies IKH-1 and IKH-2 which work on formalin-fixed, paraffin embedded tissues: characterization, clinical trials and comparative studies with HMB-45.
Topics: Animals; Antibodies, Monoclonal; Antigens, Neoplasm; Biomarkers, Tumor; Cell Transformation, Neoplastic; Clinical Trials as Topic; Formaldehyde; Humans; Hybridomas; Immunohistochemistry; Melanoma; Melanoma, Experimental; Mice; Microscopy, Immunoelectron; Paraffin; Tetradecanoylphorbol Acetate; Tissue Fixation; Tumor Cells, Cultured | 1992 |
Down-regulation of tyrosinase mRNA levels in melanoma cells by tumor promoters and by insulin.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Enzyme Induction; Gene Expression Regulation, Neoplastic; Insulin; Melanocyte-Stimulating Hormones; Melanoma, Experimental; Mice; Monophenol Monooxygenase; Phorbol 12,13-Dibutyrate; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Glucocorticoid stimulates melanogenesis and tyrosinase gene expression in B16 melanoma cells.
Topics: Animals; Dexamethasone; Gene Expression Regulation, Enzymologic; Glucocorticoids; Melanins; Melanoma, Experimental; Mice; Monophenol Monooxygenase; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
Differential genomic susceptibility in malignancy correlates with changes in ATATAT DNA-binding proteins.
Topics: Animals; Base Sequence; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Cholera Toxin; DNA-Binding Proteins; Embryo, Mammalian; Ethers, Cyclic; Genetic Predisposition to Disease; Melanocytes; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Nuclear Proteins; Okadaic Acid; Substrate Specificity; Tetradecanoylphorbol Acetate | 1991 |
Successful treatment of murine melanoma with bryostatin 1.
Topics: Animals; Antineoplastic Agents; Bryostatins; Cytotoxicity, Immunologic; Female; Killer Cells, Lymphokine-Activated; Lactones; Lung Neoplasms; Macrolides; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Spleen; Tetradecanoylphorbol Acetate | 1991 |
Protein kinase C down-regulation, and not transient activation, correlates with melanocyte growth.
Topics: Animals; Caenorhabditis elegans Proteins; Carrier Proteins; Cell Division; Cell Line; Enzyme Activation; Kinetics; Melanocytes; Melanoma, Experimental; Mice; Phorbol 12,13-Dibutyrate; Phosphoproteins; Phosphorylation; Protein Kinase C; Receptors, Drug; Tetradecanoylphorbol Acetate | 1991 |
Ultraviolet stimulated melanogenesis by human melanocytes is augmented by di-acyl glycerol but not TPA.
Topics: Alprostadil; Animals; Cell Division; Diglycerides; Dinoprost; Dinoprostone; Glycerides; Humans; Male; Melanins; Melanocytes; Melanoma, Experimental; Mice; Prostaglandin D2; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Ultraviolet Rays | 1990 |
MSH inhibits growth in a line of amelanotic hamster melanoma cells and induces increases in cyclic AMP levels and tyrosinase activity without inducing melanogenesis.
Topics: Animals; Catechol Oxidase; Cell Division; Cricetinae; Cyclic AMP; Cyclic GMP; Dihydroxyphenylalanine; Inositol 1,4,5-Trisphosphate; Melanins; Melanocyte-Stimulating Hormones; Melanoma, Experimental; Monophenol Monooxygenase; Phenotype; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine | 1989 |
Effect of tight junctional resistance on penetration of LLC-PK1 epithelial cell layers by metastatic B16-F10 melanoma cells.
Topics: Animals; Cell Division; Cell Line; Electric Conductivity; Epithelium; Intercellular Junctions; Melanoma, Experimental; Microscopy, Fluorescence; Neoplasm Metastasis; Swine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
Polyoma middle T abrogates TPA requirement of murine melanocytes and induces malignant melanoma.
Topics: Animals; Antigens, Polyomavirus Transforming; Blotting, Northern; Blotting, Western; Cell Line; Cell Transformation, Neoplastic; Melanocytes; Melanoma, Experimental; Mice; Polyomavirus; Protein Kinase C; Proto-Oncogenes; Tetradecanoylphorbol Acetate; Transfection | 1988 |
Tumor promoter-induced membrane-bound protein kinase C regulates hematogenous metastasis.
Topics: Animals; Carcinogens; Cell Line; Cell Membrane; Cytosol; Enzyme Induction; Kinetics; Lung Neoplasms; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Tetradecanoylphorbol Acetate | 1988 |
Oncostatin M: a growth regulator produced by differentiated histiocytic lymphoma cells.
Topics: Amino Acid Sequence; Biological Products; Cell Differentiation; Cell Division; Cell Line; Cytokines; Fibroblasts; Growth Inhibitors; Humans; Lymphoma, Large B-Cell, Diffuse; Macrophages; Melanoma, Experimental; Molecular Weight; Oncostatin M; Peptides; Tetradecanoylphorbol Acetate | 1986 |
A 2H NMR study on alteration of the membrane organization of mouse B16 melanoma cells treated with 12-O-tetradecanoylphorbol-13-acetate.
Topics: Animals; Carbon Radioisotopes; Cell Line; Cell Membrane; Magnetic Resonance Spectroscopy; Melanoma, Experimental; Membrane Fluidity; Membrane Lipids; Mice; Stearic Acids; Tetradecanoylphorbol Acetate; Tritium | 1986 |