Compounds > tetradecanoylphorbol acetate
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tetradecanoylphorbol acetate and B-Cell Chronic Lymphocytic Leukemia

tetradecanoylphorbol acetate has been researched along with B-Cell Chronic Lymphocytic Leukemia in 98 studies

Research

Studies (98)

TimeframeStudies, this research(%)All Research%
pre-199019 (19.39)18.7374
1990's56 (57.14)18.2507
2000's13 (13.27)29.6817
2010's10 (10.20)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Damaj, G; Ghamlouch, H; Gubler, B; Marolleau, JP; Ouled-Haddou, H; Royer, B1
Claisse, JF; Fuentes, V; Ghamlouch, H; Gubler, B; Guyart, A; Marolleau, JP; Ouled-Haddou, H; Regnier, A; Royer, B; Trudel, S1
Andritsos, L; Awan, FT; Blachly, JS; Byrd, JC; Cannon, M; Chen, CS; El-Gamal, D; Jones, J; LaFollette, TD; Lapalombella, R; Lehman, A; Maddocks, K; Williams, E; Williams, K; Woyach, JA; Wu, CH; Zhang, X; Zhong, Y1
Lau, LC; Lee, GY; Liaw, FP; Lim, AS; Lim, TH; Tien, SL1
Darwiche, W; Dupont, S; Ghamlouch, H; Gubler, B; Guignant, C; Hodroge, A; Marolleau, JP; Ouled-Haddou, H; Royer, B; Singh, AR; Trudel, S1
Bajaj, R; Gong, JZ; Holmes, PJ; Peiper, SC; Uppal, GK; Wang, ZX1
Audhuy, B; Gervais, C; Helias, C; Herbrecht, R; Mauvieux, L; Struski, S1
Cohen, GM; Dyer, MJ; Harper, N; Inoue, S; Walewska, R1
Demirtas, D; Düchler, M; Hilgarth, M; Hölbl, A; Hubmann, R; Jäger, U; Le, T; Look, T; Mitteregger, D; Schnabl, S; Schwarzmeier, JD; Shehata, M; Valent, P; Vanura, K1
Aventin, A; Briones, J; Delgado, J; Nomdedeu, J; Sanchez, J; Sierra, J1
Marsden, K; Moriarty, H; Tegg, E; Wren, C1
Andritsos, L; Breidenbach, H; Byrd, JC; Flynn, J; Heerema, NA; Jarjoura, D; Jones, J; Mo, X; Muthusamy, N; Ramanunni, A1
Barcellini, W; Calori, R; Clerici, G; Cortelezzi, A; Imperiali, FG; Montesano, R; Zanella, A; Zaninoni, A1
Barcellini, W; Imperiali, FG; Pasquini, C; Zanella, A; Zaninoni, A1
Chiurazzi, F; Dalla Mora, L; De Fanis, U; Giunta, R; Lucivero, G; Romano, C; Rotoli, B; Sellitto, A1
Danesh-Manesh, AH; Jeddi-Tehrani, M; Lüppert, A; Mellstedt, H; Mikaelsson, E; Osterborg, A; Rabbani, H; Rezvany, MR; Roohi, A; Safaie, R; Sharifian, RA; Shokri, F1
Barragán, M; Campàs, C; Castaño, E; Coll-Mulet, L; Cosialls, AM; de Frias, M; Domingo, A; Gil, J; Iglesias-Serret, D; Pons, G; Santidrián, AF1
Aventín, A; Sánchez, J1
Avalos, JS; Cañones, C; Chianelli, M; Fernández Calotti, P; Galmarini, CM; Gamberale, R; Giordano, M; Rosenstein, R; Saénz, D1
Chiorazzi, N; Dono, M; Hashimoto, S; Silver, J; Vinciguerra, V1
Csanaky, G; Milosevits, J; Ocsovszki, I; Schmelczer, M; Szomor, A; Vass, JA1
Raison, RL; Tangye, SG; Weston, KM3
Blackshear, PJ; Carballo, E; Colomer, D; Gil, J; Vives Corrons, JL1
Aarden, L; Rensink, I; van Kooten, C; van Oers, R3
Srivastava, A; Srivastava, BI; Srivastava, MD1
Catovsky, D; Ellis, J; Fantes, J; Garcìa-Marco, J; Matutes, E; Morilla, R; Oscier, D; Price, CM1
Chubb, S; Ford, R; Hittelman, WN; Meyn, RE; Plunkett, W; Robertson, LE; Story, M1
Akhtar, A; al-Katib, A; Dan, M; Hussein, ME; Mohammad, RM; Pettit, GR; Sensenbrenner, LL1
Dohlsten, M; Festin, R; Gidlöf, C; Kalland, T; Tötterman, TH; Wallgren, A1
Bushkin, Y; Demaria, S; Gottesman, SR; Schwab, R1
Boal, TR; Lichtman, MA; Segel, GB; Woodlock, TJ; Young, DA1
Murphy, JJ; Norton, JD2
Caligaris-Cappio, F; Carlsson, M; Lantz, M; Larsson, LG; Nilsson, K; Schena, M1
Alvarez-Mon, M; Garcia-Suarez, J; Hernandez, M; Lapeña, P; Prieto, A; Reyes, E1
Desai, ZR; Lavabre-Bertrand, T; McManus, AP1
Babusíková, O; Hrivnáková, A; Klobusická, M; Koníková, E; Kusenda, J; Mesárosová, A1
Jamieson, GP; Snook, MB; Thurlow, PJ; Wiley, JS1
Adami, F; Agostini, C; Cerutti, A; Facco, M; Rodeghiero, F; Sancretta, R; Semenzato, G; Tassinari, C; Trentin, L; Zambello, R1
Antosz, H; Koczkodaj, D; Kwiatkowska-Drabik, B; Wach, W1
Billet, H; Fuchs, A; Gartenhaus, R; Gentile, P; Hoffman, M; Rai, K; Wang, P1
Deed, R; Hirose, T; Murphy, JJ; Newton, J; Ning, ZQ; Norton, JD1
Bethlendy, G; Chen, X; Lichtman, MA; Segel, GB; Woodlock, TJ; Young, DA1
Polliack, A; Rabinowitz, R; Schlesinger, M; Shubinsky, G1
Abts, H; Diehl, V; Kube, D; Tesch, H; Von Knethen, A1
Hulkkonen, J; Hurme, M; Vilpo, J; Vilpo, L1
Bendall, LJ; Gu, B; Wiley, JS1
Hurme, M; Knuutila, S; Larramendy, ML; Siitonen, SM; Vilpo, JA; Vilpo, L; Zhu, Y1
Goller, M; Kneitz, C; Seggewiss, R; Serfling, E; Tony, HP; Yaman, A1
Brieva, JA; Cámara, C; Medina, F; Navas, G; Sampalo, A; Segundo, C1
Aktan, M; Cefle, K; Oztürk, S; Palanduz, S; Perkçelen, Y; Serakinci, N1
Barragán, M; Bellosillo, B; Campàs, C; Colomer, D; Gil, J; Pons, G1
al-Katib, A; Clarkson, BD; Koziner, B; McKenzie, S; Wang, CY1
Caligaris-Cappio, F; Carlsson, M; Gaidano, G; Gottardi, D; Larsson, LG; Nilsson, K; Schena, M1
Islam, LN; Wilkinson, PC1
Buschle, M; Drexler, HG; Gignac, SM; Hoffbrand, AV1
Johansson, K; Leanderson, T; Nilsson, K1
Brenner, MK; Buschle, M; Chen, IS; Drexler, HG; Gignac, SM; Rooney, CM1
Murphy, JJ; Norton, JD; Yaxley, JC1
Belvin, MP; Freedman, AS; Griffin, JD; Penta, AC; Spertini, O; Tedder, TF1
Bartrons, R; Colomer, D; Vives Corrons, JL1
Bridges, JM; Desai, ZR; Stephenson, CF1
Ferrarini, M; Heltai, S; Inverardi, L; Poggi, A; Sabbadini, MG; Vicari, A; Villa, A; Zocchi, MR1
Brown, R; Hoffman, H; Mani, M; Pompeo, L; Segel, GB; Silber, R; Woodlock, TJ1
Aguilar-Santelises, M; Eriksson, I; Hartzell, P; Jondal, M; McConkey, DJ; Mellstedt, H; Orrenius, S1
Ideka, H; Ikeda, H; Kanakura, Y; Matsumura, I; Mitsui, H; Tamaki, T; Tarui, S; Yagura, H; Yonezawa, T1
Buschie, M; Drexler, HG; Gignac, SM; Hoffbrand, AV; Pettit, GR1
Attisano, C; Bianchi, A; Cardona, S; di Celle, PF; Fierro, MT; Foa, R; Guarini, A; Massaia, M; Tos, AG1
Melo, JV; Nikoloutsopoulos, A; Skinner, J; Zola, H; Zowtyj, HN1
Mackie, MJ; Maddy, AH; Wu, ZW1
Crawford, DH; Walls, EV1
Kitani, T; Kuratsune, H; Machii, T; Morita, T; Nishimori, Y; Nojima, J; Owada, MK; Shibano, M; Tagawa, S; Tokumine, Y1
Arcuri, RA; De Souza, MH; Marques-Silva, VM; Rumjanek, VM; Teixeira, MC1
Shiosaka, T; Tanaka, Y1
Poppema, S; Visser, L1
Beiske, K; Clark, EA; Godal, T; Holte, H; Ledbetter, JA; Smeland, EB1
Hoogerbrugge, H; Löwenberg, B; Moberts, R; Touw, I; van Agthoven, T1
Bartram, CR; Brenner, MK; Drexler, HG; Hoffbrand, AV; Janssen, JW1
de la Calle, O; Engel, P; Gallart, T; Inglés, J1
Drexler, HG; Gignac, SM; Hoffbrand, AV; Jones, RA; Pettit, GR; Scott, CS1
Leanderson, T; Mårtensson, IL; Nilsson, K1
Bengtsson, M; Carlsson, M; Nilsson, K; Rosén, A; Sundström, C; Tötterman, TH1
Mackie, MJ; Maddy, AH; Sanderson, A; Smith, SK1
Gangavalli, A; Gazitt, Y; Thurman, GB1
Guazzi, S; Rubartelli, A; Sitia, R1
Cazenave, PA; Henry-Toulmé, N; Sarthou, P1
Collins, RD; Cousar, JB; Kinney, MC; Vogler, LB; Whitlock, J1
Inoue, R; Kitani, T; Kuratsune, H; Machii, T; Nakamura, Y; Nishimori, Y; Tokumine, Y; Ueda, E; Waki, K1
Hamano, T; Iwasaki, T; Nagai, K; Yasuda, Y1
Brenner, MK; Drexler, HG; Gignac, SM; Hoffbrand, AV1
Carlsson, M; Matsson, P; Nilsson, K; Rosén, A; Sundström, C; Tötterman, TH1
Takeuchi, H1
Feuerstein, N; Mond, JJ1
Hoffman, P; Pesando, JM; Stucki, M1

Other Studies

98 other study(ies) available for tetradecanoylphorbol acetate and B-Cell Chronic Lymphocytic Leukemia

ArticleYear
A combination of cytokines rescues highly purified leukemic CLL B-cells from spontaneous apoptosis in vitro.
    PloS one, 2013, Volume: 8, Issue:3

    Topics: Aged; Aged, 80 and over; Apoptosis; B-Lymphocytes; Cell Separation; Cell Survival; Cytokines; Female; Humans; Interleukin-4; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

2013
Phorbol myristate acetate, but not CD40L, induces the differentiation of CLL B cells into Ab-secreting cells.
    Immunology and cell biology, 2014, Volume: 92, Issue:7

    Topics: Aged; Aged, 80 and over; Antibody Formation; Antigens, Surface; B-Lymphocytes; CD40 Ligand; Cell Differentiation; Cytokines; Female; Gene Expression Regulation, Neoplastic; Humans; Immunoglobulin M; Immunophenotyping; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Phenotype; Tetradecanoylphorbol Acetate; Transcription, Genetic

2014
PKC-β as a therapeutic target in CLL: PKC inhibitor AEB071 demonstrates preclinical activity in CLL.
    Blood, 2014, Aug-28, Volume: 124, Issue:9

    Topics: Apoptosis; beta Catenin; Cell Proliferation; Cell Survival; Drug Screening Assays, Antitumor; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Protein Kinase C beta; Protein Kinase Inhibitors; Pyrroles; Quinazolines; Receptors, Antigen, B-Cell; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Microenvironment; Wnt Signaling Pathway

2014
CpG Oligonucleotide and Interleukin 2 stimulation enables higher cytogenetic abnormality detection rates than 12-o-tetradecanolyphorbol-13-acetate in Asian patients with B-cell chronic lymphocytic leukemia (B-CLL).
    International journal of hematology, 2014, Volume: 100, Issue:6

    Topics: Aged; Asian People; Chromosome Aberrations; Cytogenetics; Female; Humans; In Situ Hybridization, Fluorescence; Interleukin-2; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Oligodeoxyribonucleotides; Sensitivity and Specificity; Tetradecanoylphorbol Acetate

2014
Factors involved in CLL pathogenesis and cell survival are disrupted by differentiation of CLL B-cells into antibody-secreting cells.
    Oncotarget, 2015, Jul-30, Volume: 6, Issue:21

    Topics: Antibody-Producing Cells; Apoptosis; B-Lymphocytes; CD40 Ligand; Cell Culture Techniques; Cell Cycle; Cell Differentiation; Cell Survival; Cells, Cultured; Cytokines; Enzyme-Linked Immunosorbent Assay; Gene Expression; Humans; Immunoblotting; Immunoglobulin Isotypes; Immunophenotyping; Inhibitor of Apoptosis Proteins; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoid Enhancer-Binding Factor 1; Oligodeoxyribonucleotides; Reverse Transcriptase Polymerase Chain Reaction; Survivin; Tetradecanoylphorbol Acetate

2015
Efficacy of DSP30-IL2/TPA for detection of cytogenetic abnormalities in chronic lymphocytic leukaemia/small lymphocytic lymphoma.
    International journal of laboratory hematology, 2016, Volume: 38, Issue:5

    Topics: Chromosome Aberrations; Female; Humans; In Situ Hybridization, Fluorescence; Interleukin-2; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Oligonucleotides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

2016
Stimulation of B-cell lymphoproliferations with CpG-oligonucleotide DSP30 plus IL-2 is more effective than with TPA to detect clonal abnormalities.
    Leukemia, 2009, Volume: 23, Issue:3

    Topics: B-Lymphocytes; Cell Division; Cells, Cultured; Chromosome Aberrations; Chromosome Banding; Cohort Studies; Female; Humans; In Situ Hybridization, Fluorescence; Interleukin-2; Karyotyping; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocyte Activation; Lymphoma, B-Cell; Lymphoproliferative Disorders; Male; Metaphase; Mitogens; Oligonucleotides; Tetradecanoylphorbol Acetate

2009
Enhanced Fas-associated death domain recruitment by histone deacetylase inhibitors is critical for the sensitization of chronic lymphocytic leukemia cells to TRAIL-induced apoptosis.
    Molecular cancer therapeutics, 2009, Volume: 8, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Inducing Factor; Blotting, Western; Depsipeptides; Drug Synergism; Fas-Associated Death Domain Protein; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Intracellular Signaling Peptides and Proteins; Leukemia, Lymphocytic, Chronic, B-Cell; Phosphorylation; Protein Kinase C; Protein Kinase C beta; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein-Tyrosine Kinases; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor; Signal Transduction; src-Family Kinases; Syk Kinase; Tetradecanoylphorbol Acetate; TNF-Related Apoptosis-Inducing Ligand; Tumor Cells, Cultured

2009
NOTCH2 links protein kinase C delta to the expression of CD23 in chronic lymphocytic leukaemia (CLL) cells.
    British journal of haematology, 2010, Volume: 148, Issue:6

    Topics: Antigens, Neoplasm; Biomarkers, Tumor; Humans; Interferon-gamma; Leukemia, Lymphocytic, Chronic, B-Cell; Neoplasm Proteins; Prognosis; Protein Kinase C-delta; Receptor, Notch2; Receptors, IgE; RNA Interference; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

2010
The use of tetradecanoylphorbol acetate-stimulated peripheral blood cells enhances the prognostic value of interphase fluorescence in situ hybridization in patients with chronic lymphocytic leukemia.
    Genes, chromosomes & cancer, 2010, Volume: 49, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Chi-Square Distribution; Cohort Studies; Female; Humans; In Situ Hybridization, Fluorescence; Interphase; Kaplan-Meier Estimate; Leukemia, Lymphocytic, Chronic, B-Cell; Leukocytes, Mononuclear; Male; Middle Aged; Predictive Value of Tests; Prognosis; Stimulation, Chemical; Tetradecanoylphorbol Acetate

2010
Cytogenetic investigations of chronic lymphocytic leukemia.
    Cancer genetics and cytogenetics, 2010, Apr-15, Volume: 198, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Cell Culture Techniques; Cell Proliferation; Cytogenetic Analysis; Female; Humans; Interleukin-2; Karyotyping; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Mitotic Index; Oligonucleotides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

2010
Enhanced detection of chromosomal abnormalities in chronic lymphocytic leukemia by conventional cytogenetics using CpG oligonucleotide in combination with pokeweed mitogen and phorbol myristate acetate.
    Cancer genetics, 2011, Volume: 204, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Chromosome Aberrations; Humans; Karyotyping; Leukemia, Lymphocytic, Chronic, B-Cell; Middle Aged; Oligodeoxyribonucleotides; Pokeweed Mitogens; Sensitivity and Specificity; Tetradecanoylphorbol Acetate

2011
In vitro production of anti-RBC antibodies and cytokines in chronic lymphocytic leukemia.
    American journal of hematology, 2002, Volume: 71, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Anti-Idiotypic; Antibody Formation; Autoimmunity; Erythrocytes; Female; Humans; Immunoglobulin G; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Phytohemagglutinins; Pokeweed Mitogens; Reference Values; Tetradecanoylphorbol Acetate

2002
Cytokine modulation of nuclear factor-kappaB activity in B-chronic lymphocytic leukemia.
    Experimental hematology, 2003, Volume: 31, Issue:3

    Topics: Aged; Aged, 80 and over; Apoptosis; Case-Control Studies; Cytokines; DNA Fragmentation; Electrophoretic Mobility Shift Assay; Female; Humans; Interleukin-13; Interleukin-4; Leukemia, Lymphocytic, Chronic, B-Cell; Leukocytes, Mononuclear; Lymphocyte Activation; Male; Middle Aged; NF-kappa B; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta

2003
Effects of preactivated autologous T lymphocytes on CD80, CD86 and CD95 expression by chronic lymphocytic leukemia B cells.
    Leukemia & lymphoma, 2003, Volume: 44, Issue:11

    Topics: Aged; Aged, 80 and over; Antigens, CD; Apoptosis; B-Lymphocytes; B7-1 Antigen; B7-2 Antigen; CD40 Ligand; Coculture Techniques; fas Receptor; Female; Humans; Immunophenotyping; Ionomycin; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocyte Activation; Male; Membrane Glycoproteins; Middle Aged; T-Lymphocytes; Tetradecanoylphorbol Acetate; Up-Regulation

2003
Fibromodulin, an extracellular matrix protein: characterization of its unique gene and protein expression in B-cell chronic lymphocytic leukemia and mantle cell lymphoma.
    Blood, 2005, Jun-15, Volume: 105, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Antigens, CD; Antigens, CD19; Antigens, Differentiation, T-Lymphocyte; Biomarkers, Tumor; Blotting, Western; CD5 Antigens; Cell Line, Transformed; Cell Line, Tumor; Coculture Techniques; Collagen; Cytoplasm; DNA Mutational Analysis; DNA, Complementary; Extracellular Matrix; Extracellular Matrix Proteins; Female; Fibroblasts; Fibromodulin; Flow Cytometry; Gene Expression Regulation, Neoplastic; Hematologic Neoplasms; Humans; Immunoblotting; Lectins, C-Type; Leukemia, B-Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, T-Cell; Leukocytes, Mononuclear; Lymphoma, Mantle-Cell; Male; Middle Aged; Mutation; Palatine Tonsil; Proteoglycans; Receptors, Interleukin-2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors

2005
Regulation of Akt/PKB by phosphatidylinositol 3-kinase-dependent and -independent pathways in B-cell chronic lymphocytic leukemia cells: role of protein kinase C{beta}.
    Journal of leukocyte biology, 2006, Volume: 80, Issue:6

    Topics: Apoptosis; Carcinogens; Chromones; Enzyme Inhibitors; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Models, Biological; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase C; Protein Kinase C beta; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Receptors, Cytokine; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

2006
Detection of chromosomal abnormalities in chronic lymphocytic leukemia increased by interphase fluorescence in situ hybridization in tetradecanoylphorbol acetate-stimulated peripheral blood cells.
    Cancer genetics and cytogenetics, 2007, Volume: 175, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Chromosome Aberrations; Female; Humans; In Situ Hybridization, Fluorescence; Interphase; Leukemia, Lymphocytic, Chronic, B-Cell; Leukocytes, Mononuclear; Lymphocyte Count; Male; Middle Aged; Reproducibility of Results; Tetradecanoylphorbol Acetate

2007
Modulation of the human equilibrative nucleoside transporter1 (hENT1) activity by IL-4 and PMA in B cells from chronic lymphocytic leukemia.
    Biochemical pharmacology, 2008, Feb-15, Volume: 75, Issue:4

    Topics: Antineoplastic Agents; Apoptosis; B-Lymphocytes; Cell Line, Tumor; Equilibrative Nucleoside Transporter 1; Humans; Interleukin-4; Leukemia, Lymphocytic, Chronic, B-Cell; Tetradecanoylphorbol Acetate; Vidarabine

2008
Clonal heterogeneity in membrane expression of CD5 in a patient with chronic lymphocytic leukemia.
    Annals of the New York Academy of Sciences, 1995, Sep-29, Volume: 764

    Topics: Antigens, Neoplasm; Antigens, Surface; B-Lymphocyte Subsets; Base Sequence; CD5 Antigens; Clone Cells; Cohort Studies; Gene Expression Regulation, Leukemic; Gene Rearrangement, B-Lymphocyte, Heavy Chain; Genes, Immunoglobulin; Humans; Immunoglobulin G; Immunoglobulin Heavy Chains; Immunoglobulin Variable Region; Leukemia, Lymphocytic, Chronic, B-Cell; Molecular Sequence Data; Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Sequence Alignment; Sequence Homology, Nucleic Acid; Tetradecanoylphorbol Acetate

1995
Changes in adhesion molecule expression and function in B-cell chronic lymphocytic leukaemia after in vitro interferon-alpha stimulation.
    European journal of haematology, 1995, Volume: 54, Issue:1

    Topics: Adult; Aged; Cell Adhesion; Cell Adhesion Molecules; Endothelium, Vascular; Female; Humans; Integrin alpha Chains; Intercellular Adhesion Molecule-1; Interferon alpha-2; Interferon-alpha; L-Selectin; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocyte Function-Associated Antigen-1; Male; Middle Aged; Polysaccharides; Receptors, Very Late Antigen; Recombinant Proteins; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1995
Phorbol ester activates CD5+ leukaemic B cells via a T cell-independent mechanism.
    Immunology and cell biology, 1995, Volume: 73, Issue:1

    Topics: Antigens, CD; B-Lymphocytes; CD5 Antigens; Flow Cytometry; Humans; Immunoglobulin M; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocyte Activation; Lymphocyte Cooperation; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1995
Phosphorylation of the MARCKS family of protein kinase C substrates in human B chronic lymphocytic leukemia cells.
    Leukemia, 1995, Volume: 9, Issue:5

    Topics: Amino Acid Sequence; B-Lymphocytes; Humans; Intracellular Signaling Peptides and Proteins; Leukemia, Lymphocytic, Chronic, B-Cell; Membrane Proteins; Molecular Sequence Data; Myristoylated Alanine-Rich C Kinase Substrate; Neoplasm Proteins; Phosphorylation; Precipitin Tests; Protein Kinase C; Proteins; RNA, Messenger; Substrate Specificity; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1995
TNF-alpha induces spreading of B-CLL via the CD11c/CD18 molecule.
    American journal of hematology, 1993, Volume: 44, Issue:4

    Topics: Antigens, CD; B-Lymphocytes; CD11 Antigens; CD18 Antigens; Cell Adhesion; Cell Division; Culture Techniques; Fluorescent Antibody Technique; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Prednisone; Recombinant Proteins; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

1993
Soluble interleukin-2 receptor, soluble CD8 and soluble intercellular adhesion molecule-1 levels in hematologic malignancies.
    Leukemia & lymphoma, 1994, Volume: 12, Issue:3-4

    Topics: Antigens, CD; Biomarkers; Biomarkers, Tumor; CD8 Antigens; Cell Adhesion Molecules; Cell Line; Enzyme-Linked Immunosorbent Assay; Humans; Intercellular Adhesion Molecule-1; Leukemia; Leukemia, Hairy Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid, Acute; Leukemia, Prolymphocytic; Leukemia, T-Cell; Mycosis Fungoides; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Receptors, Interleukin-2; Recurrence; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1994
Trisomy 12 in B-cell chronic lymphocytic leukaemia: assessment of lineage restriction by simultaneous analysis of immunophenotype and genotype in interphase cells by fluorescence in situ hybridization.
    British journal of haematology, 1994, Volume: 87, Issue:1

    Topics: Aged; Chromosomes, Human, Pair 12; Female; Genotype; Humans; Immunoenzyme Techniques; Immunophenotyping; In Situ Hybridization, Fluorescence; Interphase; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Neoplastic Stem Cells; Tetradecanoylphorbol Acetate; Trisomy; Tumor Cells, Cultured

1994
Induction of apoptotic cell death in chronic lymphocytic leukemia by 2-chloro-2'-deoxyadenosine and 9-beta-D-arabinosyl-2-fluoroadenine.
    Blood, 1993, Jan-01, Volume: 81, Issue:1

    Topics: Adenosine Triphosphate; Apoptosis; Cladribine; Cycloheximide; Dactinomycin; DNA, Neoplasm; Egtazic Acid; Guanosine Triphosphate; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocytes; Microscopy, Electron; Puromycin; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Uridine Triphosphate; Vidarabine

1993
Bryostatin 1-induced hairy cell features on chronic lymphocytic leukemia cells in vitro.
    Experimental hematology, 1993, Volume: 21, Issue:1

    Topics: Acid Phosphatase; Aged; Aged, 80 and over; Antigens, CD; Antigens, Differentiation, B-Lymphocyte; Bryostatins; CD11 Antigens; Cell Adhesion Molecules; Cell Differentiation; Enzyme Activation; Female; Humans; Immunophenotyping; Lactones; Lectins; Leukemia, Hairy Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Macrolides; Male; Middle Aged; Protein Kinase C; Sialic Acid Binding Ig-like Lectin 2; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1993
Efficient killing of chronic B-lymphocytic leukemia cells by superantigen-directed T cells.
    Blood, 1993, Aug-15, Volume: 82, Issue:4

    Topics: Antibodies, Monoclonal; Antigens; Antigens, CD; Antigens, Differentiation, B-Lymphocyte; CD18 Antigens; Cell Adhesion Molecules; Cell Line; Cytokines; Cytotoxicity, Immunologic; Enterotoxins; HLA-DR Antigens; Humans; Intercellular Adhesion Molecule-1; Killer Cells, Lymphokine-Activated; Leukemia, Lymphocytic, Chronic, B-Cell; Staphylococcus aureus; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1993
Soluble beta 2-microglobulin-free class I heavy chains are released from the surface of activated and leukemia cells by a metalloprotease.
    The Journal of biological chemistry, 1994, Mar-04, Volume: 269, Issue:9

    Topics: Antigens, CD; Antigens, Differentiation, B-Lymphocyte; beta 2-Microglobulin; CD4 Antigens; Flow Cytometry; Histocompatibility Antigens Class I; HLA-DR Antigens; Humans; Leukemia, B-Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, T-Cell; Macromolecular Substances; Metalloendopeptidases; Phenanthrolines; Receptors, Transferrin; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Zinc

1994
Phorbol ester-induced membrane proteins in chronic leukemic B-lymphocytes. Candidate proteins for the L-system amino acid transporter.
    The Journal of biological chemistry, 1993, Jul-25, Volume: 268, Issue:21

    Topics: Affinity Labels; Amino Acid Transport Systems; Autoradiography; Azides; B-Lymphocytes; Blotting, Western; Carrier Proteins; Cells, Cultured; Humans; Immunoglobulins; Iodine Radioisotopes; Leukemia, Lymphocytic, Chronic, B-Cell; Membrane Proteins; Sulfur Radioisotopes; Tetradecanoylphorbol Acetate

1993
Phorbol ester induction of early response gene expression in lymphocytic leukemia and normal human B-cells.
    Leukemia research, 1993, Volume: 17, Issue:8

    Topics: B-Lymphocytes; Cells, Cultured; Gene Expression; Genes, fos; Genes, jun; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Oncogenes; Palatine Tonsil; Proto-Oncogenes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1993
Interleukin-2 enhances the production of tumor necrosis factor-alpha in activated B-type chronic lymphocytic leukemia (B-CLL) cells.
    Leukemia, 1993, Volume: 7, Issue:2

    Topics: DNA, Neoplasm; Humans; Interleukin-2; Interleukin-4; Leukemia, Lymphocytic, Chronic, B-Cell; Receptors, Cell Surface; Receptors, Tumor Necrosis Factor; RNA, Messenger; Staphylococcus aureus; Tetradecanoylphorbol Acetate; Thioredoxins; Tumor Necrosis Factor-alpha

1993
Diminished DNA synthesis in T cells from B chronic lymphocytic leukemia after phytohemagglutinin, anti-CD3, and phorbol myristate acetate mitogenic signals.
    Experimental hematology, 1993, Volume: 21, Issue:12

    Topics: Aged; Aged, 80 and over; Antibodies, Monoclonal; CD3 Complex; Cell Division; Cells, Cultured; DNA; Female; Flow Cytometry; Humans; Interleukin-2; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Mitogens; Phytohemagglutinins; Protein Kinase C; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymidine; Tritium

1993
Effect of IL-4 and IL-6 on the proliferation and differentiation of B-chronic lymphocytic leukemia cells.
    Leukemia, 1993, Volume: 7, Issue:4

    Topics: Aged; Cell Differentiation; Cell Division; Dose-Response Relationship, Drug; Female; Humans; Immunoglobulin G; Immunoglobulin M; Interleukin-4; Interleukin-6; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1993
B-cell chronic lymphocytic leukaemia populations respond stochastically to combinations of growth signals in vitro.
    Leukemia research, 1993, Volume: 17, Issue:6

    Topics: Aged; B-Lymphocytes; Cells, Cultured; Clone Cells; Female; Humans; Immunophenotyping; Interferon-gamma; Interleukin-2; Interleukin-4; Ki-67 Antigen; Leukemia, Lymphocytic, Chronic, B-Cell; Leukocytes, Mononuclear; Lymphocyte Activation; Lymphocytes; Male; Middle Aged; Neoplasm Proteins; Neoplasm Staging; Nuclear Proteins; T-Lymphocytes; Tetradecanoylphorbol Acetate

1993
Immune phenotype and some enzyme patterns in phorbol ester-induced chronic lymphocytic leukemia cells.
    Neoplasma, 1995, Volume: 42, Issue:5

    Topics: Animals; Antigens, CD; HLA-DR Antigens; Humans; Immunophenotyping; Leukemia, Lymphocytic, Chronic, B-Cell; Mice; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1995
Extracellular ATP causes of loss of L-selectin from human lymphocytes via occupancy of P2Z purinocepters.
    Journal of cellular physiology, 1996, Volume: 166, Issue:3

    Topics: Adenosine Triphosphate; Alkaloids; Calcium; Cells, Cultured; Down-Regulation; Humans; L-Selectin; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocytes; Magnesium; Protein Kinase C; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1996
Interleukin-15 promotes the growth of leukemic cells of patients with B-cell chronic lymphoproliferative disorders.
    Blood, 1996, Apr-15, Volume: 87, Issue:8

    Topics: Adult; B-Lymphocytes; Base Sequence; Cell Division; Cells, Cultured; Female; Humans; Interleukin-15; Interleukin-2; Interleukins; Leukemia, Hairy Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Molecular Sequence Data; Neoplasm Proteins; Neoplastic Stem Cells; Receptors, Interleukin-2; Recombinant Proteins; Stimulation, Chemical; Tetradecanoylphorbol Acetate

1996
Leukaemic B-cell maturation: studies on immunoglobulin secretion mediated by two signalling systems in vitro.
    Cytobios, 1995, Volume: 84, Issue:336

    Topics: B-Lymphocytes; Cell Differentiation; Enzyme-Linked Immunosorbent Assay; Humans; Immunoglobulin G; Immunoglobulin kappa-Chains; Immunoglobulin lambda-Chains; Immunoglobulin M; Immunoglobulins; Immunophenotyping; Leukemia, B-Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Lipopolysaccharides; Lymphocyte Activation; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1995
Differentiating agents do not induce a true hairy cell phenotype in B-CLL cells in vitro.
    Leukemia & lymphoma, 1996, Volume: 22, Issue:1-2

    Topics: Acid Phosphatase; Antigens, CD; Antigens, Neoplasm; B-Lymphocytes; Biomarkers, Tumor; Bryostatins; Cell Differentiation; Enzyme Activation; Humans; Immunophenotyping; Isoenzymes; Lactones; Leukemia, Hairy Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Macrolides; Neoplastic Stem Cells; Protein Kinase C; Tartrate-Resistant Acid Phosphatase; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured

1996
Early response gene signalling in bryostatin-stimulated primary B chronic lymphocytic leukaemia cells in vitro.
    The Biochemical journal, 1996, Oct-01, Volume: 319 ( Pt 1)

    Topics: Bryostatins; DNA Replication; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Gene Expression Regulation, Neoplastic; Genes, Immediate-Early; Genes, myc; Humans; Immunoglobulin M; Lactones; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocyte Activation; Macrolides; Oligonucleotides, Antisense; RNA; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Up-Regulation

1996
Association of HSP60-like proteins with the L-system amino acid transporter.
    Archives of biochemistry and biophysics, 1997, Feb-01, Volume: 338, Issue:1

    Topics: Amino Acid Sequence; Amino Acid Transport Systems; Amino Acids; B-Lymphocytes; Biological Transport, Active; Carrier Proteins; Cell Membrane; Chaperonin 60; Humans; In Vitro Techniques; Leukemia, Lymphocytic, Chronic, B-Cell; Molecular Sequence Data; Molecular Structure; Tetradecanoylphorbol Acetate

1997
Pathways controlling the expression of surface CD21 (CR2) and CD23 (Fc(epsilon)IIR) proteins in human malignant B cells.
    Leukemia & lymphoma, 1997, Volume: 25, Issue:5-6

    Topics: B-Lymphocytes; Down-Regulation; Enzyme Inhibitors; Humans; Interleukin-4; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Large B-Cell, Diffuse; Protein Synthesis Inhibitors; Receptors, Complement 3d; Receptors, IgE; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Up-Regulation

1997
Expression of p56lck in B-cell neoplasias.
    Leukemia & lymphoma, 1997, Volume: 26, Issue:5-6

    Topics: Antibodies, Anti-Idiotypic; B-Lymphocytes; Burkitt Lymphoma; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Genistein; HeLa Cells; Hodgkin Disease; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Lymphoma, B-Cell; Phosphorylation; Protein Kinase C; Staphylococcus aureus; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1997
Cytokines and cross-linking of sIgM augment PMA-induced activation of human leukaemic CD5+ B cells.
    Immunology and cell biology, 1997, Volume: 75, Issue:6

    Topics: Animals; Antibodies; B-Lymphocytes; CD5 Antigens; Cross-Linking Reagents; Cytokines; Humans; Immunoglobulin M; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocyte Activation; Rabbits; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1997
Diminished production of interleukin-6 in chronic lymphocytic leukaemia (B-CLL) cells from patients at advanced stages of disease. Tampere CLL Group.
    British journal of haematology, 1998, Volume: 100, Issue:3

    Topics: Aged; Enzyme-Linked Immunosorbent Assay; Female; Humans; Immunophenotyping; Interleukin-6; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Monocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

1998
Adenosine triphosphate-induced shedding of CD23 and L-selectin (CD62L) from lymphocytes is mediated by the same receptor but different metalloproteases.
    Blood, 1998, Aug-01, Volume: 92, Issue:3

    Topics: Adenosine Triphosphate; B-Lymphocytes; Biomarkers, Tumor; Calcium; Humans; Hydroxamic Acids; L-Selectin; Leukemia, Lymphocytic, Chronic, B-Cell; Metalloendopeptidases; Neoplasm Proteins; Neoplastic Stem Cells; Protease Inhibitors; Receptors, IgE; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Solubility; Tetradecanoylphorbol Acetate

1998
Interleukin-10 inhibits the in vitro proliferation of human activated leukemic CD5+ B-cells.
    Leukemia & lymphoma, 1998, Volume: 31, Issue:1-2

    Topics: CD5 Antigens; Cell Division; Cell Survival; Cytokines; Humans; Immunoglobulins; Interleukin-10; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocyte Activation; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1998
Optimized mitogen stimulation induces proliferation of neoplastic B cells in chronic lymphocytic leukemia: significance for cytogenetic analysis.The Tampere Chronic Lympocytic Leukemia group.
    Cytogenetics and cell genetics, 1998, Volume: 82, Issue:3-4

    Topics: Aged; B-Lymphocytes; Carcinogens; Cell Lineage; Chromosome Aberrations; Chromosomes, Human, Pair 11; DNA, Neoplasm; Female; Gene Deletion; Gene Expression Regulation, Neoplastic; Humans; Interleukin-2; Interphase; Leukemia, B-Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Mitogens; Mitosis; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

1998
STAT6 and the regulation of CD23 expression in B-chronic lymphocytic leukemia.
    Leukemia research, 2000, Volume: 24, Issue:4

    Topics: Biological Transport; CD40 Ligand; DNA-Binding Proteins; Humans; Interleukin-4; Leukemia, Lymphocytic, Chronic, B-Cell; Membrane Glycoproteins; Receptors, IgE; STAT1 Transcription Factor; STAT6 Transcription Factor; Tetradecanoylphorbol Acetate; Trans-Activators

2000
Chronic lymphocytic leukemia B cells inhibit spontaneous Ig production by autologous bone marrow cells: role of CD95-CD95L interaction.
    Blood, 2000, Nov-01, Volume: 96, Issue:9

    Topics: Adult; Aged; Antibodies, Monoclonal; Antibody Formation; B-Lymphocytes; Bone Marrow Cells; Cell Adhesion; Cells, Cultured; Coculture Techniques; Fas Ligand Protein; fas Receptor; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Membrane Glycoproteins; Middle Aged; Neoplasm Staging; Reverse Transcriptase Polymerase Chain Reaction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

2000
Sister chromatid exchange frequency in B-cells stimulated by TPA in chronic lymphocytic leukemia.
    Cancer genetics and cytogenetics, 2000, Volume: 123, Issue:1

    Topics: Aged; B-Lymphocytes; Cytogenetic Analysis; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Sister Chromatid Exchange; Tetradecanoylphorbol Acetate

2000
Involvement of protein kinase C and phosphatidylinositol 3-kinase pathways in the survival of B-cell chronic lymphocytic leukemia cells.
    Blood, 2002, Apr-15, Volume: 99, Issue:8

    Topics: Aged; Aged, 80 and over; Cell Survival; Enzyme Inhibitors; Female; Humans; Interleukin-4; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

2002
Phorbol ester-induced hairy cell features on chronic lymphocytic leukemia cells in vitro.
    American journal of hematology, 1992, Volume: 40, Issue:4

    Topics: Acid Phosphatase; Aged; Antigens, CD; Antigens, Differentiation, B-Lymphocyte; CD11 Antigens; Cell Adhesion Molecules; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Female; Humans; Lectins; Leukemia, Hairy Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocytes; Male; Microscopy, Electron; Middle Aged; Phenotype; Phorbol Esters; Precipitin Tests; Sialic Acid Binding Ig-like Lectin 2; Tetradecanoylphorbol Acetate; Time Factors

1992
Growth- and differentiation-associated expression of bcl-2 in B-chronic lymphocytic leukemia cells.
    Blood, 1992, Jun-01, Volume: 79, Issue:11

    Topics: Aged; Antigens, CD; B-Lymphocytes; CD5 Antigens; Cell Division; Female; Gene Expression; Gene Expression Regulation, Neoplastic; Humans; Immunoglobulin M; Immunohistochemistry; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocyte Activation; Male; Middle Aged; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; RNA, Messenger; Tetradecanoylphorbol Acetate

1992
Restoration with phorbol ester of a locomotor defect in human leukaemic lymphocytes: a visual study of chronic lymphocytic leukaemia cells.
    Invasion & metastasis, 1992, Volume: 12, Issue:1

    Topics: Aged; Aged, 80 and over; Autoradiography; Cells, Cultured; Chemotaxis, Leukocyte; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocytes; Middle Aged; RNA; Tetradecanoylphorbol Acetate; Tritium; Uridine

1992
Interleukin-4 inhibits both paracrine and autocrine tumor necrosis factor-alpha-induced proliferation of B chronic lymphocytic leukemia cells.
    Blood, 1992, Sep-01, Volume: 80, Issue:5

    Topics: Adult; Aged; Antigens, CD; CD5 Antigens; Cell Division; Cells, Cultured; Cytokines; Female; Humans; Interleukin-2; Interleukin-4; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Receptors, Cell Surface; Receptors, Tumor Necrosis Factor; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

1992
Down-regulation of CD5 mRNA in B-chronic lymphocytic leukemia cells by differentiation-inducing agents.
    European journal of immunology, 1990, Volume: 20, Issue:5

    Topics: Aged; Antigens, CD; Antigens, Differentiation; Bryostatins; Calcimycin; CD5 Antigens; Cell Differentiation; Female; Gene Expression Regulation, Neoplastic; Humans; Lactones; Leukemia, Lymphocytic, Chronic, B-Cell; Macrolides; Male; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1990
Phorbol ester treatment down-regulates immunoglobulin RNA steady-state levels in B type chronic lymphocytic leukemia and non-Hodgkin's lymphoma cells.
    Leukemia, 1990, Volume: 4, Issue:9

    Topics: Animals; Down-Regulation; Gene Expression Regulation, Neoplastic; Genes, Immunoglobulin; Humans; Immunoglobulin mu-Chains; Immunoglobulins; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Non-Hodgkin; Mice; RNA; RNA Splicing; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured

1990
Transfection and gene expression in normal and malignant primary B lymphocytes.
    Journal of immunological methods, 1990, Oct-04, Volume: 133, Issue:1

    Topics: Antigens, Differentiation; B-Lymphocytes; CD5 Antigens; Cell Separation; Chloramphenicol O-Acetyltransferase; Cytomegalovirus; Electric Stimulation; Enhancer Elements, Genetic; Fluorescent Antibody Technique; Gene Expression; Herpesvirus 4, Human; Human T-lymphotropic virus 1; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocyte Activation; Plasmids; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured

1990
Evidence for protein kinase C--independent pathways mediating phorbol ester induced plasmacytoid differentiation of B chronic lymphocytic leukemia cells.
    Biochimica et biophysica acta, 1991, Mar-19, Volume: 1092, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; B-Lymphocytes; Cell Differentiation; Cell Division; DNA; Fluorescent Antibody Technique; Gene Expression; Humans; Immunoglobulin M; Isoquinolines; Leukemia, Lymphocytic, Chronic, B-Cell; Piperazines; Plasma Cells; Protein Kinase C; RNA; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1991
Regulation of leukocyte adhesion molecule-1 (TQ1, Leu-8) expression and shedding by normal and malignant cells.
    Leukemia, 1991, Volume: 5, Issue:4

    Topics: Cell Adhesion Molecules; Down-Regulation; Fluorescent Antibody Technique; Humans; L-Selectin; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukocytes, Mononuclear; Precipitin Tests; Receptors, Leukocyte-Adhesion; Tetradecanoylphorbol Acetate

1991
Effect of TPA on fructose 2,6-bisphosphate levels and protein kinase C activity in B-chronic lymphocytic leukemia (B-CLL).
    Biochimica et biophysica acta, 1991, Nov-21, Volume: 1097, Issue:4

    Topics: B-Lymphocytes; Fructosediphosphates; Humans; Lactates; Lactic Acid; Leukemia, Lymphocytic, Chronic, B-Cell; Protein Kinase C; Subcellular Fractions; Tetradecanoylphorbol Acetate

1991
The proliferative activity of B-chronic lymphocytic leukaemia lymphocytes prior to and after stimulation with TPA and PHA.
    Leukemia research, 1991, Volume: 15, Issue:11

    Topics: Aged; B-Lymphocytes; Bromodeoxyuridine; Cell Division; Cells, Cultured; Female; Humans; Ki-67 Antigen; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Nuclear Proteins; Phenotype; Phytohemagglutinins; Tetradecanoylphorbol Acetate

1991
Signal requirements for activation of leukaemic T cells from a chronic lymphocytic leukaemia (T-CLL).
    Clinical and experimental immunology, 1990, Volume: 82, Issue:1

    Topics: Antibodies, Monoclonal; Antigens, Differentiation, T-Lymphocyte; CD2 Antigens; CD28 Antigens; CD3 Complex; Concanavalin A; Cytotoxicity, Immunologic; Flow Cytometry; Humans; Interleukin-2; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocyte Activation; Male; Middle Aged; Receptors, Antigen, T-Cell; Receptors, Immunologic; Receptors, Interleukin-2; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate

1990
Decreased L system amino acid transport and decreased gamma-glutamyl transpeptidase are independent processes in human chronic lymphocytic leukemia B-lymphocytes.
    Journal of cellular physiology, 1990, Volume: 145, Issue:2

    Topics: Amino Acids; Animals; Antibodies; B-Lymphocytes; Biological Transport; Cell Differentiation; Cell Membrane; gamma-Glutamyltransferase; Humans; In Vitro Techniques; Kidney; Leukemia, Lymphocytic, Chronic, B-Cell; Rats; Tetradecanoylphorbol Acetate

1990
Induction of DNA fragmentation in chronic B-lymphocytic leukemia cells.
    Journal of immunology (Baltimore, Md. : 1950), 1991, Feb-01, Volume: 146, Issue:3

    Topics: Antibodies, Monoclonal; Calcimycin; Calcium; Cell Survival; DNA, Neoplasm; Glucocorticoids; Humans; Immunoglobulin M; Leukemia, Lymphocytic, Chronic, B-Cell; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1991
High-affinity interleukin 2 receptors on B cell chronic lymphocytic leukemia cells are induced by phorbol myristate acetate but not by calcium ionophore.
    Immunology letters, 1991, Volume: 27, Issue:2

    Topics: Antigens, Surface; B-Lymphocytes; Binding Sites; Calcimycin; Calcium; Electrophoresis, Polyacrylamide Gel; Humans; Immunophenotyping; Interleukin-2; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocyte Activation; Protein Kinase C; Receptors, Interleukin-2; Tetradecanoylphorbol Acetate

1991
Expression of proto-oncogene c-jun during differentiation of B-chronic lymphocytic leukemia.
    Leukemia, 1990, Volume: 4, Issue:6

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Bryostatins; Calcimycin; Cell Differentiation; Enzyme Activation; Gene Expression; Humans; Isoquinolines; Kinetics; Lactones; Leukemia, Lymphocytic, Chronic, B-Cell; Macrolides; Piperazines; Protein Kinase C; Proto-Oncogene Mas; Proto-Oncogenes; RNA, Messenger; Second Messenger Systems; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured

1990
Production of tumor necrosis factor-alpha by B-cell chronic lymphocytic leukemia cells: a possible regulatory role of TNF in the progression of the disease.
    Blood, 1990, Jul-15, Volume: 76, Issue:2

    Topics: Antibodies; Cell Count; Cell Division; Gene Expression; Humans; Interferon-gamma; Interleukin-2; Leukemia, Hairy Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Phytohemagglutinins; Recombinant Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

1990
The leukocyte-common antigen (CD45) complex and B-lymphocyte activation.
    Human immunology, 1990, Volume: 27, Issue:4

    Topics: Antibodies, Anti-Idiotypic; Antigens, CD; Antigens, Differentiation; B-Lymphocytes; Calcimycin; Histocompatibility Antigens; Humans; Immunoglobulin M; Interleukin-4; Leukemia, Lymphocytic, Chronic, B-Cell; Leukocyte Common Antigens; Lymphocyte Activation; Molecular Weight; Palatine Tonsil; Tetradecanoylphorbol Acetate

1990
The analysis of the variation of the surface proteins of leukemic lymphocytes of B-chronic lymphocytic leukemia patients by high performance liquid chromatography.
    Leukemia, 1990, Volume: 4, Issue:12

    Topics: Antigens, Differentiation; Antigens, Differentiation, B-Lymphocyte; B-Lymphocytes; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Histocompatibility Antigens; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Leukocyte Common Antigens; Membrane Proteins; Phenotype; Polyethylene Glycols; Receptors, Complement; Receptors, Complement 3d; Tetradecanoylphorbol Acetate

1990
Effects of a phorbol ester on activation and immortalization of leukaemic B cells by Epstein-Barr virus.
    Leukemia research, 1990, Volume: 14, Issue:4

    Topics: B-Lymphocytes; Cell Transformation, Viral; Herpesvirus 4, Human; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocyte Activation; Tetradecanoylphorbol Acetate

1990
Association of protein tyrosine phosphorylation with B cell differentiation induced by 12-O-tetradecanoylphorbol-13-acetate (TPA).
    Leukemia, 1990, Volume: 4, Issue:10

    Topics: B-Lymphocytes; Cell Differentiation; Coumaric Acids; Humans; Leukemia, Hairy Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Phosphorylation; Protein-Tyrosine Kinases; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine

1990
Myeloid leukemia differentiation by phorbol ester and retinoic acid: a practical approach.
    Journal of clinical laboratory analysis, 1990, Volume: 4, Issue:5

    Topics: Cell Transformation, Neoplastic; Diagnosis, Differential; Humans; Leukemia, Erythroblastic, Acute; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid; Leukemia, Promyelocytic, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tetradecanoylphorbol Acetate; Tretinoin

1990
Expression of selected genes in differentiated HL-60 cells and primary cells from human leukemias.
    Cancer biochemistry biophysics, 1990, Volume: 11, Issue:1

    Topics: Base Sequence; Cell Differentiation; Cloning, Molecular; Dimethyl Sulfoxide; DNA, Neoplasm; Gene Expression; Genomic Library; Granulocytes; Humans; Leukemia, Experimental; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid; Molecular Sequence Data; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1990
Cell-type-specific early response gene expression during plasmacytoid differentiation of human B lymphocytic leukemia cells.
    Biochimica et biophysica acta, 1990, Jul-30, Volume: 1049, Issue:3

    Topics: B-Lymphocytes; Base Sequence; Cell Differentiation; Cloning, Molecular; Gene Expression Regulation, Neoplastic; Humans; Kinetics; Leukemia, Lymphocytic, Chronic, B-Cell; Molecular Sequence Data; Plasma Cells; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Up-Regulation

1990
Induction of B-cell chronic lymphocytic leukaemia and hairy cell leukaemia like phenotypes by phorbol ester treatment of normal peripheral blood B-cells.
    British journal of haematology, 1990, Volume: 75, Issue:3

    Topics: B-Lymphocytes; Cell Differentiation; Cells, Cultured; Humans; Leukemia, Hairy Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Phenotype; Spleen; Tetradecanoylphorbol Acetate

1990
Triggering of neoplastic B cells via surface IgM and the cell surface antigens CD20 and CDw40. Responses differ from normal blood B cells and are restricted to certain morphologic subsets.
    International journal of cancer, 1988, Oct-15, Volume: 42, Issue:4

    Topics: Antigens, CD20; Antigens, Differentiation, B-Lymphocyte; Antigens, Surface; B-Lymphocytes; CD40 Antigens; DNA; Humans; Immunoglobulin M; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocyte Activation; Lymphoma, Non-Hodgkin; Phenotype; Receptors, Interleukin-4; Receptors, Mitogen; Tetradecanoylphorbol Acetate

1988
Proliferative response of highly purified B chronic lymphocytic leukemia cells in serum free culture to interleukin-2 and tumor necrosis factors alpha and beta.
    Leukemia research, 1989, Volume: 13, Issue:11

    Topics: Antigens, CD; Antigens, CD19; Antigens, Differentiation; Antigens, Differentiation, B-Lymphocyte; B-Lymphocytes; CD5 Antigens; Cell Division; Humans; Immunologic Techniques; Interleukin-2; Interleukin-4; Karyotyping; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphotoxin-alpha; Receptors, Antigen, B-Cell; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

1989
Rapid expression of protooncogenes c-fos and c-myc in B-chronic lymphocytic leukemia cells during differentiation induced by phorbol ester and calcium ionophore.
    Blood, 1989, May-01, Volume: 73, Issue:6

    Topics: Blotting, Northern; Calcimycin; Cell Differentiation; Cell Division; DNA; Drug Synergism; Gene Expression Regulation; Humans; Immunoglobulin M; In Vitro Techniques; Leukemia, Lymphocytic, Chronic, B-Cell; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-myc; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1989
Cellular activation without proliferation to B cell growth factor and interleukin 2 in chronic lymphocytic leukaemia B cells stimulated with phorbol ester plus calcium ionophore.
    Clinical and experimental immunology, 1989, Volume: 76, Issue:1

    Topics: B-Lymphocytes; Calcimycin; Cell Extracts; Cells, Cultured; Humans; Interleukin-2; Interleukin-4; Interleukins; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocyte Activation; Tetradecanoylphorbol Acetate

1989
Bryostatin 1 induces differentiation of B-chronic lymphocytic leukemia cells.
    Blood, 1989, Volume: 74, Issue:5

    Topics: Aged; Antineoplastic Agents; B-Lymphocytes; Biomarkers, Tumor; Bryostatins; Calcimycin; Cell Adhesion; Cell Aggregation; Cell Differentiation; DNA, Neoplasm; Female; Humans; Immunoglobulins; Lactones; Leukemia, Lymphocytic, Chronic, B-Cell; Macrolides; Male; Middle Aged; Receptors, Antigen, B-Cell; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1989
Transcriptional regulation of immunoglobulin expression in a chronic lymphocytic leukemia cell line.
    European journal of immunology, 1989, Volume: 19, Issue:9

    Topics: B-Lymphocytes; Base Sequence; Cell Division; Enhancer Elements, Genetic; Gene Expression Regulation, Neoplastic; Genes, Immunoglobulin; Humans; Immunoglobulin kappa-Chains; Immunoglobulin mu-Chains; Leukemia, Lymphocytic, Chronic, B-Cell; Molecular Sequence Data; Promoter Regions, Genetic; Regulatory Sequences, Nucleic Acid; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured

1989
Interleukin 4 strongly augments or inhibits DNA synthesis and differentiation of B-type chronic lymphocytic leukemia cells depending on the co-stimulatory activation and progression signals.
    European journal of immunology, 1989, Volume: 19, Issue:5

    Topics: Antigens, Differentiation, B-Lymphocyte; B-Lymphocytes; Cell Differentiation; DNA; Humans; Interleukin-2; Interleukin-4; Interleukins; Interphase; Leukemia, Lymphocytic, Chronic, B-Cell; Receptors, Fc; Receptors, IgE; Staphylococcus aureus; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1989
The role of cell maturation in the generation of phenotypic heterogeneity in B-cell chronic lymphocytic leukaemia.
    Immunology, 1989, Volume: 68, Issue:3

    Topics: Antigens, CD; Antigens, Differentiation; Cell Differentiation; Histocompatibility Antigens; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Leukocyte Common Antigens; Lymphocytes; Membrane Glycoproteins; Receptors, Antigen, B-Cell; Tetradecanoylphorbol Acetate

1989
Induction of surface marker changes and monoclonal idiotypic immunoglobulin secretion in lymphoma/leukemia cells: comparative study with interleukin-1, interleukin-2, interleukin-4, 8-bromo-guanosine, pokeweed mitogen, and tetradecanoyl phorbol-13-acetate
    Molecular biotherapy, 1989, Volume: 1, Issue:6

    Topics: Antibodies, Monoclonal; Antigens, Surface; B-Lymphocytes; Cell Differentiation; Guanosine; Humans; Immunoglobulin Idiotypes; Interleukins; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma; Pokeweed Mitogens; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1989
Regulation of IgM biosynthesis in human chronic lymphocytic leukemia. Normal and neoplastic B cells respond differently to TPA.
    Leukemia research, 1989, Volume: 13, Issue:12

    Topics: B-Lymphocytes; Humans; Immunoglobulin M; Leukemia, Lymphocytic, Chronic, B-Cell; Receptors, Antigen, B-Cell; Tetradecanoylphorbol Acetate

1989
Membrane IgM cross-linking is not coupled to protein kinase C translocation in WEHI-231 B lymphoma cells.
    European journal of immunology, 1989, Volume: 19, Issue:7

    Topics: Animals; Antigen-Antibody Reactions; B-Lymphocytes; Blotting, Western; Calcium; Cell Compartmentation; Cell Division; Immune Tolerance; Immunoglobulin M; In Vitro Techniques; Leukemia, Lymphocytic, Chronic, B-Cell; Mice; Protein Kinase C; Receptors, Antigen, B-Cell; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1989
Response of neoplasms of B cell lineage to the proliferative effects of B cell growth factor and the phorbol ester TPA.
    The American journal of pathology, 1989, Volume: 134, Issue:4

    Topics: B-Lymphocytes; Cell Division; Cell Transformation, Neoplastic; DNA; Humans; Interleukin-4; Interleukins; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma; Lymphoma, Non-Hodgkin; Palatine Tonsil; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tetradecanoylphorbol Acetate

1989
The effect of 12-O-tetradecanoylphorbol-13-acetate (TPA) on leukemic cells from chronic B cell leukemia.
    Leukemia, 1989, Volume: 3, Issue:7

    Topics: B-Lymphocytes; Cell Adhesion; Cell Differentiation; Cell Transformation, Neoplastic; Histocytochemistry; Humans; Leukemia, Hairy Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Tetradecanoylphorbol Acetate

1989
Functional analysis of an Epstein-Barr virus-nontransformed human B cell line.
    Acta haematologica, 1988, Volume: 80, Issue:3

    Topics: Antibody-Producing Cells; Antigens, Surface; B-Lymphocytes; Cell Line; Cell Transformation, Viral; Herpesvirus 4, Human; Humans; Interleukin-4; Interleukins; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocyte Activation; Receptors, Antigen, B-Cell; Rosette Formation; Tetradecanoylphorbol Acetate

1988
Expression of tartrate-resistant acid phosphatase in B-CLL treated with phorbol ester or phorbol ester plus calcium ionophore.
    European journal of haematology, 1988, Volume: 41, Issue:3

    Topics: Acid Phosphatase; Aged; B-Lymphocytes; Calcimycin; Drug Synergism; Female; Humans; Isoenzymes; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Prolymphocytic; Male; Middle Aged; Tartrates; Tetradecanoylphorbol Acetate

1988
Phorbol ester and B cell-stimulatory factor synergize to induce B-chronic lymphocytic leukemia cells to simultaneous immunoglobulin secretion and DNA synthesis.
    Leukemia, 1988, Volume: 2, Issue:11

    Topics: Antigens, Differentiation, B-Lymphocyte; B-Lymphocytes; Cell Cycle; Cell Differentiation; Culture Media; DNA; Dose-Response Relationship, Immunologic; Drug Synergism; Humans; Immunoglobulins; Interleukin-4; Interleukins; Kinetics; Leukemia, Lymphocytic, Chronic, B-Cell; Leukocyte Count; Lymphocyte Activation; Tetradecanoylphorbol Acetate

1988
[Phenotypes of leukemic cells from chronic B cell leukemia and their proliferative responses to several kinds of mitogens or lymphokines: PHA or phorbol ester (TPA) induces a high responsibility to B cell growth factor (BCGF) in the leukemic cells].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1988, Volume: 29, Issue:12

    Topics: Adult; Aged; Cell Division; Drug Synergism; Female; Humans; Interleukin-4; Interleukins; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphokines; Male; Middle Aged; Mitogens; Phenotype; Phytohemagglutinins; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1988
"Numatrin," a nuclear matrix protein associated with induction of proliferation in B lymphocytes.
    The Journal of biological chemistry, 1987, Aug-15, Volume: 262, Issue:23

    Topics: Animals; Antibodies, Anti-Idiotypic; B-Lymphocytes; Cell Line; Cell Nucleus; DNA; Electrophoresis, Polyacrylamide Gel; Humans; Kinetics; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocyte Activation; Mice; Mitogens; Molecular Weight; Nuclear Proteins; Nucleophosmin; Ribonucleoproteins; Tetradecanoylphorbol Acetate

1987
Altered expression of surface antigens with appearance of HLA class II molecules on a malignant human B-cell line.
    Human immunology, 1987, Volume: 19, Issue:4

    Topics: Antigens, Neoplasm; Antigens, Surface; B-Lymphocytes; Cell Differentiation; Gene Expression Regulation; HLA-D Antigens; HLA-DR Antigens; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1987