tetradecanoylphorbol acetate has been researched along with Astrocytoma in 63 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (17.46) | 18.7374 |
| 1990's | 27 (42.86) | 18.2507 |
| 2000's | 23 (36.51) | 29.6817 |
| 2010's | 2 (3.17) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ahn, YH; Jung, JS; Kim, HS; Moon, BI | 1 |
| Jung, JS; Jung, K; Kim, DH; Kim, HS | 1 |
| Brown, EM; Chattopadhyay, N; Tfelt-Hansen, J | 1 |
| Akagawa, K; Mikoshiba, K; Nakayama, T; Yamamori, T | 2 |
| Downes, CP; Proud, CG; Tang, X; Wang, L | 1 |
| Brodie, C; Chang, TS; Gao, ZG; Jacobson, KA; Kim, SG; Soltysiak, KA | 1 |
| Batty, IH; Downes, CP; Fleming, IN | 1 |
| Branchi, I; Capone, F; Costa, LG; Fattori, V; Giordano, G; Madia, F; Vitalone, A | 1 |
| Endres, K; Fahrenholz, F; Mueller, U; Postina, R; Schroeder, A | 1 |
| Ahn, BH; Bae, YS; Min, DS; Min, G | 1 |
| Benveniste, EN; Laver, T; Nozell, S; Patel, K | 1 |
| Contreras-Galindo, R; López, P; Vélez, R; Yamamura, Y | 1 |
| Ahn, BH; Kwon, TK; Lee, YH; Min, do S; Park, MH | 1 |
| Han, SJ; Hyun, JW; Kim, DH; Kim, HS; Kim, SY | 1 |
| Amos, S; Carpenter, JE; diPierro, CG; Hussaini, IM; Kohutek, ZA; Mut, M; Redpath, GT; Shaffrey, ME; Wang, J; Xiao, A; Zhao, Y | 1 |
| Anda, T; Kaminogo, M; Kitange, G; Nagata, I; Shabani, HK; Shibata, S; Tsunoda, K | 1 |
| Axelrod, J; Henneberry, RC; Hirata, F; Mallorga, P; Strittmatter, WT; Tallman, JF | 1 |
| Cadman, ED; Lee, CM; Witte, DG | 1 |
| Manzini, S; Palma, C; Urbani, F | 1 |
| Aschmies, SH; Carlson, RO | 1 |
| Arneson-Rotert, LJ; Liewer, SA; Toews, ML | 1 |
| Brown, JH; Goldstein, D; Kennedy, E; Nieto, M | 1 |
| Cazaubon, S; Couraud, PO; Parker, PJ; Strosberg, AD | 1 |
| Imajoh-Ohmi, S; Inagaki, M; Moritoh, C; Ogawara, M; Takai, Y; Taketani, Y; Tomono, Y; Tsutsumi, O | 1 |
| Purkiss, JR | 1 |
| Hoffman, J; Toews, M; Whittle, S | 1 |
| Bauer, J; Berger, M; Fiebich, BL; Lieb, K; Schaller, H | 1 |
| Fukui, H; Hijzelendoorn, JC; Leurs, R; Smit, MJ; Timmerman, H | 1 |
| Asai, K; Kato, T; Kimura, S; Mizuno, H; Moriyama, A; Uemura, K; Wada, Y | 1 |
| Alonso, A; Bayon, Y; Garcia-Sancho, J; Hernandez, M; Leslie, C; Nieto, ML; Nuñez, L; Sanchez Crespo, M | 1 |
| Houghton, PJ; Luo, W; Sharif, M; Sharif, TR | 1 |
| Manzini, S; Palma, C | 1 |
| Abe, H; Ishii, N; Sakuma, S; Sawamura, Y; Shinohe, Y; Tada, M | 1 |
| Kuroda, Y; Kurohara, K; Satoh, J; Yukitake, M | 1 |
| Costa, LG; Guizzetti, M; Wei, M | 1 |
| Ghali, M; Schneider-Schaulies, J | 1 |
| Aloisi, F; Ambrosini, E; Erfle, V; Kohleisen, B; Levi, G; Shumay, E; Slepko, N | 1 |
| Costa, LG; Guizzetti, M; Wei, M; Yost, M | 1 |
| Kumasaka, T; Kurita, M; Mashiko, H; Nakahata, N; Nakanishi, H; Niwa, S; Ogata, M; Takano, S | 1 |
| Di Padova, F; Fearns, C; Gram, H; Han, J; Kline, L; Ulevitch, RJ; Zurini, M | 1 |
| Kuroda, Y; Satoh, J | 1 |
| Catlin, MC; Costa, LG; Kavanagh, TJ | 1 |
| Chen, YZ; Zhu, BG; Zhu, DH | 1 |
| Costa, LG; Guizzetti, M; Lu, H | 1 |
| Arias-Montaño, JA; Hernández-Angeles, A; Ortega, A; Soria-Jasso, LE | 1 |
| Kouno, Si; Kumasaka, T; Kurita, M; Mashiko, H; Nakahata, N; Niwa, Si; Rai, M | 1 |
| Lee, CM; Tung, WL; Young, JD | 1 |
| Johnson, RA; Toews, ML | 1 |
| Norman-O'Guin, K; Shafit-Zagardo, B; Sharma, N | 1 |
| Brown, JH; Martinson, EA; Trilivas, I | 1 |
| Brown, JH; Martinson, E; Trejo, J; Trilivas, I | 1 |
| Hoover, RK; Toews, ML | 1 |
| Brown, JH; Goldstein, D; Martinson, EA | 1 |
| Garin-Chesa, P; Rettig, WJ; Triche, TJ | 1 |
| Lee, JC; Simon, PL; Young, PR | 1 |
| Brown, JH; Buss, JE; Orellana, SA; Quilliam, LA | 1 |
| Brown, JH; Orellana, SA; Solski, PA | 1 |
| Brown, JH; Harden, TK; Heng, MM | 1 |
| Barna, BP; Deodhar, SD; James, K | 1 |
| Kokunai, T; Matsumoto, S; Tamaki, N | 1 |
| Blackshear, PJ; Huang, JK; Nemenoff, RA; Spach, DH; Stumpo, DJ | 1 |
| Eisinger, M; Marko, O; Ogata, S; Old, LJ | 1 |
63 other study(ies) available for tetradecanoylphorbol acetate and Astrocytoma
| Article | Year |
|---|---|
Exogenous C2 Ceramide Suppresses Matrix Metalloproteinase Gene Expression by Inhibiting ROS Production and MAPK Signaling Pathways in PMA-Stimulated Human Astroglioma Cells.
Topics: Astrocytoma; Cell Line, Tumor; Cell Movement; Ceramides; Enzyme-Linked Immunosorbent Assay; Gene Expression; Humans; MAP Kinase Signaling System; Matrix Metalloproteinases; Mitogen-Activated Protein Kinases; NADPH Oxidase 4; NADPH Oxidases; NF-kappa B; Phosphorylation; Promoter Regions, Genetic; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription Factor AP-1 | 2016 |
Selective inhibition of MMP-9 gene expression by mangiferin in PMA-stimulated human astroglioma cells: involvement of PI3K/Akt and MAPK signaling pathways.
Topics: Antineoplastic Agents, Phytogenic; Astrocytoma; Binding Sites; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Dose-Response Relationship, Drug; Down-Regulation; Gene Expression Regulation, Enzymologic; Humans; MAP Kinase Signaling System; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Neoplasm Invasiveness; NF-kappa B; Phosphatidylinositol 3-Kinase; Phosphorylation; Promoter Regions, Genetic; Protease Inhibitors; Proto-Oncogene Proteins c-akt; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transfection; Xanthones | 2012 |
PKC, p42/44 MAPK and p38 MAPK regulate hepatocyte growth factor secretion from human astrocytoma cells.
Topics: Astrocytoma; Cell Division; Cell Transformation, Neoplastic; Enzyme Inhibitors; Hepatocyte Growth Factor; Humans; MAP Kinase Kinase 1; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Neoplasm Invasiveness; p38 Mitogen-Activated Protein Kinases; Protein Kinase C; Protein Serine-Threonine Kinases; Protein Synthesis Inhibitors; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2002 |
Expression of syntaxin 1C, an alternative splice variant of HPC-1/syntaxin 1A, is enhanced by phorbol-ester stimulation in astroglioma: participation of the PKC signaling pathway.
Topics: Alternative Splicing; Antigens, Surface; Astrocytoma; Base Sequence; Cell Line; Enzyme Inhibitors; Humans; Immunoblotting; Molecular Sequence Data; Nerve Tissue Proteins; Polymerase Chain Reaction; Protein Kinase C; Signal Transduction; Syntaxin 1; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 2003 |
Muscarinic receptor-mediated activation of p70 S6 kinase 1 (S6K1) in 1321N1 astrocytoma cells: permissive role of phosphoinositide 3-kinase.
Topics: Androstadienes; Astrocytoma; Calcium Signaling; Carbachol; Chelating Agents; Enzyme Activation; Enzyme Inhibitors; Humans; Kinetics; Phosphatidylinositol 3-Kinases; Phosphatidylinositols; Protein Kinase Inhibitors; Protein Kinases; Receptors, Muscarinic; Ribosomal Protein S6 Kinases, 70-kDa; Sirolimus; Tetradecanoylphorbol Acetate; TOR Serine-Threonine Kinases; Tumor Cells, Cultured; Wortmannin | 2003 |
P2Y6 nucleotide receptor activates PKC to protect 1321N1 astrocytoma cells against tumor necrosis factor-induced apoptosis.
Topics: Animals; Apoptosis; Astrocytes; Astrocytoma; Calcium Signaling; Cell Membrane; Drug Interactions; Enzyme Inhibitors; Humans; Mitogen-Activated Protein Kinases; Protein Isoforms; Protein Kinase C; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Receptors, Purinergic P2; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Type C Phospholipases; Uridine Diphosphate | 2003 |
Muscarinic-receptor-mediated inhibition of insulin-like growth factor-1 receptor-stimulated phosphoinositide 3-kinase signalling in 1321N1 astrocytoma cells.
Topics: Astrocytoma; Calcium; Carbachol; Cell Line, Tumor; Enzyme Activation; Humans; Inositol 1,4,5-Trisphosphate; Insulin; Insulin Receptor Substrate Proteins; Ionomycin; Mitogen-Activated Protein Kinases; Okadaic Acid; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Platelet-Derived Growth Factor; Protein Kinase C; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptor, IGF Type 1; Receptors, Muscarinic; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Tetradecanoylphorbol Acetate; Type C Phospholipases | 2004 |
Activation of syntaxin 1C, an alternative splice variant of HPC-1/syntaxin 1A, by phorbol 12-myristate 13-acetate (PMA) suppresses glucose transport into astroglioma cells via the glucose transporter-1 (GLUT-1).
Topics: Alternative Splicing; Antigens, Surface; Astrocytoma; Biological Transport; Cell Line, Tumor; Glucose; Glucose Transporter Type 1; Humans; Molecular Sequence Data; Monosaccharide Transport Proteins; Nerve Tissue Proteins; Protein Isoforms; Signal Transduction; Syntaxin 1; Tetradecanoylphorbol Acetate | 2004 |
Differential in vitro neurotoxicity of the flame retardant PBDE-99 and of the PCB Aroclor 1254 in human astrocytoma cells.
Topics: Apoptosis; Astrocytes; Astrocytoma; Cell Line, Tumor; Cell Survival; Chlorodiphenyl (54% Chlorine); Dose-Response Relationship, Drug; Down-Regulation; Enzyme Inhibitors; Flame Retardants; Formazans; Halogenated Diphenyl Ethers; Humans; Indoles; Isoenzymes; L-Lactate Dehydrogenase; Maleimides; Phenyl Ethers; Protein Kinase C; Tetradecanoylphorbol Acetate; Tetrazolium Salts; Trypan Blue; Tumor Suppressor Protein p53 | 2004 |
Shedding of the amyloid precursor protein-like protein APLP2 by disintegrin-metalloproteinases.
Topics: ADAM Proteins; ADAM17 Protein; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Astrocytoma; Blotting, Western; Cattle; Cell Culture Techniques; Cell Differentiation; Cell Extracts; Cell Line; Cell Line, Tumor; Dipeptides; Disintegrins; Endopeptidases; Gene Expression Regulation; Humans; Metalloproteases; Mice; Mice, Transgenic; Mutagenesis; Nerve Tissue Proteins; Neuroblastoma; Protease Inhibitors; Solubility; Tetradecanoylphorbol Acetate; Tretinoin; Up-Regulation | 2005 |
Phospholipase D is activated and phosphorylated by casein kinase-II in human U87 astroglioma cells.
Topics: 1-Butanol; Astrocytoma; Blotting, Western; Casein Kinase II; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Glutathione Transferase; Humans; Kinetics; Phospholipase D; Phosphorylation; Precipitin Tests; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate | 2006 |
Mechanism of IFN-beta-mediated inhibition of IL-8 gene expression in astroglioma cells.
Topics: Acetylation; Active Transport, Cell Nucleus; Astrocytoma; Cell Line, Tumor; DNA-Binding Proteins; Down-Regulation; Gene Expression Regulation; Histone Deacetylase 1; Histone Deacetylases; Histones; Humans; Interferon-beta; Interleukin-8; NF-kappa B; Nuclear Receptor Co-Repressor 2; Promoter Regions, Genetic; Protein Binding; Repressor Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription Factors; Transcriptional Activation | 2006 |
HIV-1 infection increases the expression of human endogenous retroviruses type K (HERV-K) in vitro.
Topics: Astrocytoma; CD4-Positive T-Lymphocytes; Cell Line, Tumor; Endogenous Retroviruses; Flow Cytometry; Gene Expression; HIV Infections; HIV Seronegativity; HIV Seropositivity; HIV-1; Humans; In Vitro Techniques; Ionomycin; Ionophores; Leukocytes, Mononuclear; RNA, Viral; Tetradecanoylphorbol Acetate; Viral Load | 2007 |
Up-regulation of cyclooxygenase-2 by cobalt chloride-induced hypoxia is mediated by phospholipase D isozymes in human astroglioma cells.
Topics: Astrocytoma; Cell Hypoxia; Cobalt; Cyclooxygenase 2; Dinoprostone; Enzyme Activation; Gene Expression Regulation, Neoplastic; Humans; Isoenzymes; Lipopolysaccharides; Pertussis Toxin; Phospholipase D; Phospholipases A2; Signal Transduction; Tetradecanoylphorbol Acetate; Type C Phospholipases; Up-Regulation | 2007 |
Repression of matrix metalloproteinase gene expression by ginsenoside Rh2 in human astroglioma cells.
Topics: Astrocytoma; Binding Sites; Blotting, Western; Cell Line, Tumor; Cell Movement; Cell Survival; DNA-Binding Proteins; Dose-Response Relationship, Drug; Electrophoretic Mobility Shift Assay; Gene Expression Regulation, Enzymologic; Ginsenosides; Humans; Matrix Metalloproteinase 1; Matrix Metalloproteinase 14; Matrix Metalloproteinase 3; Matrix Metalloproteinase 9; Matrix Metalloproteinases; Molecular Structure; Neoplasm Invasiveness; NF-kappa B; Phosphorylation; Protein Binding; Reverse Transcriptase Polymerase Chain Reaction; Tetradecanoylphorbol Acetate; Transcription Factor AP-1 | 2007 |
Protein kinase C-alpha-mediated regulation of low-density lipoprotein receptor related protein and urokinase increases astrocytoma invasion.
Topics: Animals; Astrocytoma; Cell Line, Tumor; Cell Movement; Humans; Immunoprecipitation; Low Density Lipoprotein Receptor-Related Protein-1; Male; Mice; Mice, SCID; Neoplasm Invasiveness; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C-alpha; Tetradecanoylphorbol Acetate; Urokinase-Type Plasminogen Activator | 2007 |
Expression of the constitutively activated RelA/NF-kappaB in human astrocytic tumors and the in vitro implication in the regulation of urokinase-type plasminogen activator, migration, and invasion.
Topics: Astrocytoma; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Nucleus; Culture Media, Conditioned; Curcumin; Enzyme Induction; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Neoplasm Invasiveness; Neoplasm Proteins; NF-kappa B; Oligonucleotides, Antisense; Retrospective Studies; RNA, Messenger; RNA, Neoplasm; Single-Blind Method; Tetradecanoylphorbol Acetate; Transcription Factor RelA; Urokinase-Type Plasminogen Activator | 2005 |
Mepacrine blocks beta-adrenergic agonist-induced desensitization in astrocytoma cells.
Topics: Adenylyl Cyclases; Animals; Arachidonic Acids; Astrocytoma; Cells, Cultured; Isoproterenol; Melitten; Phospholipases A; Phospholipases A2; Quinacrine; Rats; Receptors, Adrenergic; Receptors, Adrenergic, beta; Tetracaine; Tetradecanoylphorbol Acetate | 1980 |
Regulation of the release of interleukin-6 from human astrocytoma cells.
Topics: Adenylyl Cyclases; Alzheimer Disease; Astrocytoma; Calcium; Cycloheximide; Dinoprostone; Enzyme-Linked Immunosorbent Assay; Glial Fibrillary Acidic Protein; Histamine; Humans; Indomethacin; Inositol Phosphates; Interleukin-1; Interleukin-6; Kinetics; Protein Kinase C; Substance P; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Interleukin-6 production by U373 MG, a human astrocytoma cell line: different pathways involved in substance P and lipopolysaccharide activation.
Topics: Alkaloids; Astrocytoma; Bucladesine; Calcimycin; Cholera Toxin; Humans; Indomethacin; Interleukin-6; Lipopolysaccharides; Receptors, Neurokinin-1; Staurosporine; Substance P; Sulfonamides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Tyrosine kinase activity is essential for interleukin-1 beta--stimulated production of interleukin-6 in U373 human astrocytoma cells.
Topics: Astrocytes; Astrocytoma; Drug Synergism; Enzyme Activation; Humans; Interleukin-1; Interleukin-6; Protein Kinase C; Protein-Tyrosine Kinases; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Bicarbonate induces sensitization of cyclic AMP accumulation by intact 1321N1 human astrocytoma cells.
Topics: 1-Methyl-3-isobutylxanthine; Astrocytoma; Bicarbonates; Blood Physiological Phenomena; Colforsin; Cyclic AMP; Humans; Magnesium; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Rapid heterologous desensitization of muscarinic and thrombin receptor-mediated phospholipase D activation.
Topics: Astrocytoma; Carbachol; Chemical Fractionation; Down-Regulation; Enzyme Activation; Ethanol; Glycerophospholipids; Humans; Hydrolysis; Immunoblotting; Muscarinic Agonists; Phosphatidic Acids; Phosphatidylcholines; Phospholipase D; Protein Kinases; Receptors, Thrombin; Tetradecanoylphorbol Acetate; Thrombin; Tumor Cells, Cultured | 1994 |
Endothelins stimulate tyrosine phosphorylation and activity of p42/mitogen-activated protein kinase in astrocytes.
Topics: Aluminum; Aluminum Compounds; Animals; Astrocytes; Astrocytoma; Clone Cells; Endothelins; Enzyme Activation; Fluorides; Glycogen Synthase Kinase 3; Ligands; Mice; Mitogen-Activated Protein Kinase 1; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Rats; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine | 1993 |
Mitosis-specific phosphorylation of vimentin by protein kinase C coupled with reorganization of intracellular membranes.
Topics: Amino Acid Sequence; Animals; Antibodies, Monoclonal; Antibody Specificity; Astrocytoma; Cattle; CDC2 Protein Kinase; Cell Compartmentation; Cell Division; Cell Line; Enzyme Activation; Humans; Interphase; Intracellular Membranes; Mitosis; Molecular Sequence Data; Phospholipids; Phosphopeptides; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vimentin | 1996 |
Protein kinase C modulation of phosphoinositidase C in 1321N1 human astrocytoma cells.
Topics: Astrocytoma; Butanols; Cell Line; Enzyme Inhibitors; Histamine; Humans; Indoles; Inositol 1,4,5-Trisphosphate; Kinetics; Phospholipase D; Phosphoric Diester Hydrolases; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1996 |
Modulation of cyclic AMP accumulation in glial cells by exogenous phospholipase C.
Topics: Adenylate Cyclase Toxin; Astrocytoma; Colforsin; Cyclic AMP; Down-Regulation; Glioma; Humans; Isoproterenol; Lysophospholipids; Neuroglia; Pertussis Toxin; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Type C Phospholipases; Virulence Factors, Bordetella | 1996 |
Interleukin-1 beta and tumor necrosis factor-alpha induce expression of alpha 1-antichymotrypsin in human astrocytoma cells by activation of nuclear factor-kappa B.
Topics: alpha 1-Antichymotrypsin; Astrocytoma; Blotting, Northern; Bucladesine; Cell Line; Colforsin; Gene Expression Regulation, Neoplastic; Humans; Interleukin-1; NF-kappa B; Recombinant Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1996 |
Regulation of the human histamine H1 receptor stably expressed in Chinese hamster ovary cells.
Topics: Animals; Astrocytoma; Calcium; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Histamine; Humans; Protein Kinase C; Pyrilamine; Receptors, Histamine H1; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1996 |
Glucocorticoid induced the expression of mRNA and the secretion of lipocortin 1 in rat astrocytoma cells.
Topics: Animals; Annexin A1; Astrocytoma; Bucladesine; Carcinogens; Dexamethasone; Dose-Response Relationship, Drug; Glucocorticoids; Polymerase Chain Reaction; Rats; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1997 |
Cytosolic phospholipase A2 is coupled to muscarinic receptors in the human astrocytoma cell line 1321N1: characterization of the transducing mechanism.
Topics: Arachidonic Acid; Astrocytoma; Brain Neoplasms; Calcimycin; Calcium; Carbachol; Carcinogens; Cytosol; Enzyme Activation; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Ionophores; Phospholipases A; Phospholipases A2; Protein Kinase C; Receptors, Muscarinic; Tetradecanoylphorbol Acetate; Thapsigargin; Tumor Cells, Cultured | 1997 |
CGP 41251 and tamoxifen selectively inhibit mitogen-activated protein kinase activation and c-Fos phosphoprotein induction by substance P in human astrocytoma cells.
Topics: Astrocytoma; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; Cyclic AMP Response Element-Binding Protein; Enzyme Activation; Enzyme Inhibitors; Humans; Indoles; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C; Proto-Oncogene Proteins c-fos; Staurosporine; Substance P; Tamoxifen; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine | 1997 |
Substance P induces secretion of immunomodulatory cytokines by human astrocytoma cells.
Topics: Astrocytoma; Brain Neoplasms; Cytokines; Dipeptides; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Inhibitors; Humans; Indoles; Interleukin-6; Interleukin-8; Leukemia Inhibitory Factor; Lymphokines; Neoplasm Proteins; Neurokinin-1 Receptor Antagonists; Protein Kinase C; Receptors, Neurokinin-1; RNA, Messenger; RNA, Neoplasm; Staurosporine; Substance P; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1998 |
Human astrocytoma cells are capable of producing macrophage inflammatory protein-1beta.
Topics: Astrocytoma; Chemokine CCL3; Chemokine CCL4; Enzyme-Linked Immunosorbent Assay; Glioblastoma; Humans; Lipopolysaccharides; Macrophage Inflammatory Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1998 |
Constitutive and cytokine-inducible expression of prion protein gene in human neural cell lines.
Topics: Astrocytoma; Brain; Brain Neoplasms; Cell Line; Cerebellum; Cytokines; Eye Neoplasms; Gene Expression Regulation; Humans; Interferon-gamma; Interleukin-1; Interleukin-10; Neuroblastoma; Neuroglia; Neurons; Polymerase Chain Reaction; Prions; Retinoblastoma; RNA, Messenger; Teratocarcinoma; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transforming Growth Factor beta; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1998 |
The role of protein kinase C alpha and epsilon isozymes in DNA synthesis induced by muscarinic receptors in a glial cell line.
Topics: Astrocytoma; Atropine; Carbachol; Carcinogens; DNA; Dose-Response Relationship, Drug; Down-Regulation; Drug Synergism; Enzyme Inhibitors; Humans; Indoles; Isoenzymes; Maleimides; Muscarinic Agonists; Muscarinic Antagonists; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-epsilon; Radioligand Assay; Receptors, Muscarinic; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured | 1998 |
Receptor (CD46)- and replication-mediated interleukin-6 induction by measles virus in human astrocytoma cells.
Topics: Antigens, CD; Astrocytes; Astrocytoma; Calcimycin; Carrier Proteins; Gene Expression Regulation; Hemagglutinins, Viral; Humans; Interleukin-6; Intracellular Signaling Peptides and Proteins; Measles virus; Membrane Cofactor Protein; Membrane Glycoproteins; Poly I-C; Receptor Aggregation; Receptors, Virus; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Ultraviolet Rays; Vesicular stomatitis Indiana virus; Viral Envelope Proteins; Viral Fusion Proteins; Virus Replication | 1998 |
HIV-1 Nef alters the expression of betaII and epsilon isoforms of protein kinase C and the activation of the long terminal repeat promoter in human astrocytoma cells.
Topics: Acylation; AIDS Dementia Complex; Astrocytoma; Brain Neoplasms; Chloramphenicol O-Acetyltransferase; Enzyme Induction; Gene Expression Regulation, Neoplastic; Gene Products, nef; Genes, Reporter; HIV-1; Humans; Isoenzymes; Myristic Acid; nef Gene Products, Human Immunodeficiency Virus; Neoplasm Proteins; Nerve Tissue Proteins; Promoter Regions, Genetic; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-epsilon; Protein Processing, Post-Translational; Recombinant Fusion Proteins; Terminal Repeat Sequences; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured; Virus Replication | 1999 |
Exposure to 60-Hz magnetic fields and proliferation of human astrocytoma cells in vitro.
Topics: Animals; Astrocytoma; Brain Neoplasms; Carbachol; Carcinogens; Cell Division; Cerebral Cortex; Cholinergic Agents; Cold Temperature; DNA Replication; DNA, Neoplasm; Drug Synergism; Electromagnetic Fields; Enzyme Inhibitors; Humans; Indoles; Maleimides; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2000 |
Discrimination of histamine H1 and muscarinic receptor-mediated signalling pathways by phorbol ester in human astrocytoma cells.
Topics: Astrocytoma; Brain Neoplasms; Carbachol; Carcinogens; Chelating Agents; Egtazic Acid; Histamine; Humans; Muscarinic Agonists; Protein Kinase C; Receptors, Histamine H1; Receptors, Muscarinic; Signal Transduction; Tetradecanoylphorbol Acetate | 2000 |
Coordinate activation of endogenous p38alpha, beta, gamma, and delta by inflammatory stimuli.
Topics: Antibodies, Monoclonal; Astrocytoma; Cell Line; Enzyme Activation; Escherichia coli; Humans; Inflammation; Interferon-gamma; Kinetics; Lipopolysaccharides; Mitogen-Activated Protein Kinase 12; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Recombinant Proteins; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured; U937 Cells | 2000 |
Beta-catenin expression in human neural cell lines following exposure to cytokines and growth factors.
Topics: Astrocytoma; beta Catenin; Brain Neoplasms; Bucladesine; Cadherins; Cell Differentiation; Cytokines; Cytoskeletal Proteins; Gene Expression Regulation, Neoplastic; Glioma; Growth Substances; HeLa Cells; HL-60 Cells; Humans; Neuroblastoma; Neurons; Retinal Neoplasms; Retinoblastoma; Tetradecanoylphorbol Acetate; Trans-Activators; Transcription, Genetic; Tumor Cells, Cultured | 2000 |
Muscarinic receptor-induced calcium responses in astroglia.
Topics: Animals; Astrocytes; Astrocytoma; Calcium; Calcium Signaling; Carbachol; Cells, Cultured; Chelating Agents; Cholinergic Agonists; Egtazic Acid; Female; Flow Cytometry; Humans; Indoles; Muscarinic Antagonists; Pregnancy; Protein Kinase C; Rats; Receptor, Muscarinic M3; Receptors, Muscarinic; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2000 |
[The stimulation of glutamate uptake by the phorbol ester in rat cerebral cortex synaptosomes and cell line of human anaplastic astrocytoma BT-325].
Topics: Animals; Astrocytoma; Cerebral Cortex; Glutamic Acid; Humans; Male; Protein Kinase C; Rats; Synaptosomes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1998 |
Inorganic lead stimulates DNA synthesis in human astrocytoma cells: role of protein kinase Calpha.
Topics: Astrocytes; Astrocytoma; Carbachol; Carcinogens; Cell Cycle; Cell Division; Cholinergic Agonists; Culture Media, Serum-Free; DNA; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flow Cytometry; Humans; Immunoblotting; Indoles; Isoenzymes; Maleimides; Organometallic Compounds; Protein Kinase C; Protein Kinase C-alpha; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2001 |
Histamine H1 receptor activation stimulates mitogenesis in human astrocytoma U373 MG cells.
Topics: Astrocytoma; Brain Neoplasms; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Histamine; Histamine H1 Antagonists; Humans; Inositol Phosphates; Protein Kinase C; Pyrilamine; Receptors, Histamine H1; Tetradecanoylphorbol Acetate; Thymidine; Tumor Cells, Cultured; Type C Phospholipases | 2001 |
Lithium chloride at a therapeutic concentration reduces Ca2+ response in protein kinase C down-regulated human astrocytoma cells.
Topics: Astrocytoma; Binding, Competitive; Calcium; Carbachol; Cell Membrane; Dose-Response Relationship, Drug; Down-Regulation; Humans; Lithium Chloride; Protein Kinase C; Quinuclidinyl Benzilate; Tetradecanoylphorbol Acetate; Time Factors; Tritium; Tumor Cells, Cultured | 2002 |
Tachykinin-stimulated inositol phospholipid hydrolysis and taurine release from human astrocytoma cells.
Topics: Alkaloids; Astrocytoma; Brain Neoplasms; Down-Regulation; Humans; Hydrolysis; Phosphatidylinositols; Protein Kinase C; Receptors, Neurotransmitter; Receptors, Tachykinin; Staurosporine; Substance P; Tachykinins; Taurine; Tetradecanoylphorbol Acetate; Tritium; Tumor Cells, Cultured | 1992 |
Protein kinase C activators sensitize cyclic AMP accumulation by intact 1321N1 human astrocytoma cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenylate Cyclase Toxin; Astrocytoma; Carbachol; Colforsin; Cyclic AMP; Down-Regulation; Enzyme Activation; Humans; Isoproterenol; Pertussis Toxin; Phosphatidylinositols; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1990 |
Phorbol-12-myristate-13-acetate (PMA) and inhibitors of protein kinase C alter glial fibrillary acidic protein (GFAP) mRNA levels.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Astrocytoma; Dactinomycin; Glial Fibrillary Acidic Protein; Humans; Isoquinolines; Piperazines; Protein Kinase C; RNA; RNA, Messenger; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 1991 |
Rapid protein kinase C-dependent activation of phospholipase D leads to delayed 1,2-diglyceride accumulation.
Topics: Animals; Astrocytoma; Carbachol; Cell Line; Choline; Diglycerides; Enzyme Activation; Kinetics; Phosphatidic Acids; Phosphatidylethanolamines; Phosphatidylinositols; Phospholipase D; Propranolol; Protein Kinase C; Receptors, Muscarinic; Tetradecanoylphorbol Acetate | 1990 |
Multiple pathways for signal transduction through the muscarinic cholinergic receptor.
Topics: Animals; Astrocytoma; Calcium; Carbachol; Cell Division; Cell Line; Choline; Ionomycin; Kinetics; Phospholipase D; Protein Kinase C; Receptors, Muscarinic; Signal Transduction; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1990 |
Activation of protein kinase C inhibits internalization and downregulation of muscarinic receptors in 1321N1 human astrocytoma cells.
Topics: Astrocytoma; Carbachol; Cycloheximide; Down-Regulation; Enzyme Activation; Humans; N-Methylscopolamine; Protein Kinase C; Quinuclidinyl Benzilate; Receptors, Muscarinic; Scopolamine Derivatives; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Muscarinic receptor activation of phosphatidylcholine hydrolysis. Relationship to phosphoinositide hydrolysis and diacylglycerol metabolism.
Topics: Arachidonic Acid; Arachidonic Acids; Astrocytoma; Calcium; Carbachol; Cell Line; Choline; Diglycerides; Glycerides; Humans; Hydrolysis; Intracellular Fluid; Myristic Acid; Myristic Acids; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylinositols; Protein Kinase C; Receptors, Muscarinic; Tetradecanoylphorbol Acetate; Tritium | 1989 |
Stimulation of human neuronectin secretion by brain-derived growth factors.
Topics: Astrocytoma; Brain; Cell Line; Extracellular Matrix Proteins; Fibroblast Growth Factors; Humans; Nerve Tissue Proteins; Neuroectodermal Tumors, Primitive, Peripheral; Sarcoma, Ewing; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured | 1989 |
Constitutive and PMA-induced interleukin-1 production by the human astrocytoma cell line T24.
Topics: Amino Acid Sequence; Astrocytes; Astrocytoma; Base Sequence; Gene Expression Regulation; Humans; Interleukin-1; Isoelectric Point; Molecular Sequence Data; Oligonucleotide Probes; Precipitin Tests; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
Regulation of phosphoinositide hydrolysis by GTP-binding proteins, phorbol esters and botulinum toxin type D.
Topics: Astrocytoma; Botulinum Toxins; Carbachol; Cell Line; Cholera Toxin; GTP-Binding Proteins; Humans; Hydrolysis; Kinetics; Phosphatidylinositols; Signal Transduction; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1988 |
Phorbol ester inhibits phosphoinositide hydrolysis and calcium mobilization in cultured astrocytoma cells.
Topics: Astrocytoma; Calcium; Carbachol; Cells, Cultured; Humans; Hydrolysis; Phorbol Esters; Phorbols; Phosphatidylinositols; Receptors, Muscarinic; Tetradecanoylphorbol Acetate | 1985 |
Receptor reserve in the calcium-dependent cyclic AMP response of astrocytoma cells to muscarinic receptor stimulation: demonstration by agonist-induced desensitization, receptor inactivation, and phorbol ester treatment.
Topics: Astrocytoma; Calcium; Carbachol; Cells, Cultured; Cyclic AMP; Inositol Phosphates; Isoproterenol; Oxotremorine; Phorbols; Propylbenzilylcholine Mustard; Receptors, Muscarinic; Tetradecanoylphorbol Acetate | 1986 |
Activation of human monocyte tumoricidal activity by C-reactive protein.
Topics: Astrocytes; Astrocytoma; C-Reactive Protein; Carcinoma, Renal Cell; Cell Line; Cytotoxicity Tests, Immunologic; Cytotoxicity, Immunologic; Fibroblasts; Humans; Kidney Neoplasms; Melanoma; Monocytes; Phosphorylcholine; Superoxides; Tetradecanoylphorbol Acetate | 1987 |
Promoting effect of 12-O-tetradecanoylphorbol-13-acetate on neurogenic microtumors initiated by transplacental exposure to N-ethyl-N-nitrosourea.
Topics: Animals; Astrocytoma; Brain Neoplasms; Cocarcinogenesis; Ependymoma; Ethylnitrosourea; Female; Glioma; Male; Maternal-Fetal Exchange; Oligodendroglioma; Placenta; Pregnancy; Rats; Tetradecanoylphorbol Acetate | 1987 |
Protein kinase C-dependent and -independent pathways of proto-oncogene induction in human astrocytoma cells.
Topics: Astrocytoma; Carbachol; Cell Line; Epidermal Growth Factor; Humans; Inositol Phosphates; Kinetics; Molecular Weight; Peptide Mapping; Protein Kinase C; Proto-Oncogene Mas; Proto-Oncogenes; Ribosomal Protein S6; Ribosomal Proteins; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1987 |
Growth regulation of human melanocytes: mitogenic factors in extracts of melanoma, astrocytoma, and fibroblast cell lines.
Topics: Astrocytoma; Cell Division; Cell Line; Cholera Toxin; Fibroblasts; Growth Substances; Humans; Melanocytes; Melanoma; Tetradecanoylphorbol Acetate | 1985 |