tetradecanoylphorbol acetate and Alzheimer Disease

Topics: Alzheimer Disease; Amyloid beta-Peptides; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Cell Line; Cell Survival; Cyclooxygenase 2; Drug Stability; Flurbiprofen; Gene Expression; Humans; Interleukin-1beta; Naproxen; Peptide Fragments; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Thioctic Acid; Tumor Necrosis Factor-alpha

Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Calcineurin; Calcineurin Inhibitors; Calcium Ionophores; Cell Line, Tumor; Cyclosporine; DNA-Binding Proteins; Down Syndrome; Humans; Intracellular Signaling Peptides and Proteins; Ionomycin; Luciferases; Muscle Proteins; Neprilysin; NFATC Transcription Factors; RNA, Messenger; Signal Transduction; tau Proteins; Tetradecanoylphorbol Acetate

Topics: ADAM Proteins; ADAM10 Protein; Alternative Splicing; Alzheimer Disease; Amyloid Precursor Protein Secretases; Calcimycin; Carcinogens; Cell Line; Cell Membrane; Diabetes Complications; Humans; Hydroxamic Acids; Ionophores; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Membrane Proteins; Protease Inhibitors; Protein Isoforms; Protein Structure, Tertiary; Receptor for Advanced Glycation End Products; Receptors, Immunologic; RNA, Small Interfering; Tetradecanoylphorbol Acetate

Topics: Aged; Aged, 80 and over; Alzheimer Disease; Analysis of Variance; Apolipoprotein E4; Cytokines; Female; Follow-Up Studies; Humans; Lymphocytes; Male; Mental Status Schedule; Neuropsychological Tests; Radioimmunoassay; Tetradecanoylphorbol Acetate; Up-Regulation; Vitamin B 12

Topics: 4-Chloro-7-nitrobenzofurazan; Age Factors; Alzheimer Disease; Amyloid beta-Peptides; Analysis of Variance; Animals; Animals, Newborn; Astrocytes; Calcium; Cell Death; Coculture Techniques; Deoxyglucose; Disease Models, Animal; Glial Fibrillary Acidic Protein; Glucose; Hippocampus; Membrane Potential, Mitochondrial; Mice; Mice, Transgenic; NAD; NADPH Oxidases; Neurons; Oxygen Consumption; Peptide Fragments; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate

Topics: Alzheimer Disease; Antineoplastic Agents, Phytogenic; Apoptosis; Brain; Cell Death; Cell Line, Tumor; Etoposide; Humans; Neuroblastoma; Neurons; Phosphorylation; Protein Kinase C; Serine; Tetradecanoylphorbol Acetate; Transfection; X-Linked Inhibitor of Apoptosis Protein

Topics: ADAM Proteins; ADAM17 Protein; Alzheimer Disease; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Blotting, Western; Cattle; Cell Adhesion; Cell Line; Cyclic AMP-Dependent Protein Kinases; DNA, Complementary; Endopeptidases; Furin; Genetic Vectors; Humans; Metalloendopeptidases; Peptide Fragments; Phorbol Esters; Proprotein Convertases; Protein Kinase C; Rats; Signal Transduction; Subtilisins; Tetradecanoylphorbol Acetate; Time Factors; Transfection; Tumor Cells, Cultured

Topics: Adaptor Proteins, Signal Transducing; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Antimetabolites; Chlorocebus aethiops; COS Cells; Deoxyglucose; Enzyme Inhibitors; Mitogen-Activated Protein Kinase 8; Neurons; Oxidative Stress; PC12 Cells; Phosphoprotein Phosphatases; Phosphorylation; Rats; Reactive Oxygen Species; Signal Transduction; Sodium Azide; Tetradecanoylphorbol Acetate

Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Chlorocebus aethiops; COS Cells; Deoxyglucose; Endoplasmic Reticulum; Gene Expression Regulation; Golgi Apparatus; Green Fluorescent Proteins; Humans; Oxidative Stress; Phosphorylation; Protein Isoforms; Tetradecanoylphorbol Acetate

Topics: Alzheimer Disease; Animals; Blotting, Western; Cell Line, Tumor; Cloning, Molecular; Cyclic AMP-Dependent Protein Kinases; Dexamethasone; Drug Synergism; Gene Deletion; Gene Expression Regulation; Glucocorticoids; Humans; Plasmids; Promoter Regions, Genetic; Protein Kinase C; Rats; Receptors, N-Methyl-D-Aspartate; Response Elements; Reverse Transcriptase Polymerase Chain Reaction; Serum Amyloid A Protein; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription, Genetic

Topics: Adenylyl Cyclases; Alzheimer Disease; Astrocytoma; Calcium; Cycloheximide; Dinoprostone; Enzyme-Linked Immunosorbent Assay; Glial Fibrillary Acidic Protein; Histamine; Humans; Indomethacin; Inositol Phosphates; Interleukin-1; Interleukin-6; Kinetics; Protein Kinase C; Substance P; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Brain Neoplasms; Cholera Toxin; Cytoplasm; Glioma; GTP-Binding Proteins; Mutagenesis; Nerve Tissue Proteins; Plasmids; Precipitin Tests; Rats; Recombinant Proteins; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Astrocytes; Base Sequence; Enzyme Activation; HeLa Cells; Humans; Isoenzymes; Luciferases; Molecular Sequence Data; Promoter Regions, Genetic; Protein Binding; Protein Kinase C; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transcriptional Activation; Transfection

Topics: 3T3 Cells; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Humans; Kinetics; Mice; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate; Transfection

Topics: 3T3 Cells; Aluminum Chloride; Aluminum Compounds; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Chlorides; Fibroblast Growth Factor 2; Gene Expression; Genes, fos; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Mice; RNA, Messenger; Tetradecanoylphorbol Acetate

Topics: Acetylcysteine; Alzheimer Disease; Amyloid beta-Peptides; Animals; Blotting, Western; Brain; Cells, Cultured; Cycloheximide; Fibroblasts; Humans; Isoenzymes; Peptide Fragments; Protein Kinase C; Protein Kinase C-alpha; Protein Synthesis Inhibitors; Rats; Tetradecanoylphorbol Acetate

Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Protein Precursor; Antigens, CD; Base Sequence; Brain; Cytokine Receptor gp130; Fetal Proteins; Fibroblast Growth Factor 2; Gene Expression Regulation; Genes, Reporter; Humans; Interleukin-6; Lipopolysaccharides; Luciferases; Membrane Glycoproteins; Molecular Sequence Data; Neoplasm Proteins; Neuroblastoma; Neurons; Polymerase Chain Reaction; Receptors, Interleukin-6; Recombinant Fusion Proteins; RNA, Messenger; Solubility; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Tumor Cells, Cultured

Topics: Alkaloids; Alzheimer Disease; Amyloid beta-Peptides; Animals; Benzophenanthridines; Benzoquinones; Brain; Carcinogens; Cells, Cultured; Chemotaxis; Dose-Response Relationship, Drug; Enzyme Inhibitors; Lactams, Macrocyclic; Microglia; Naphthalenes; Peptide Fragments; Phenanthridines; Protein Kinase C; Protein-Tyrosine Kinases; Quinones; Rats; Rats, Wistar; Rifabutin; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate

Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Astrocytes; Brain; Cell Differentiation; Chromans; Cyclooxygenase 2; Dinoprost; Genes, Reporter; Humans; Inflammation; Interleukin-6; Isoenzymes; Membrane Proteins; Mice; Mice, Inbred C57BL; Microbodies; Microglia; Monocytes; Peptide Fragments; Prostaglandin-Endoperoxide Synthases; Receptors, Cytoplasmic and Nuclear; Recombinant Proteins; Tetradecanoylphorbol Acetate; Thiazoles; Thiazolidinediones; Transcription Factors; Transfection; Troglitazone; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Carbazoles; CHO Cells; Cricetinae; Down-Regulation; Endopeptidases; Enzyme Activation; Humans; Indoles; Isoenzymes; Maleimides; Protein Kinase C; Protein Kinase C-epsilon; Protein Processing, Post-Translational; Recombinant Proteins; Tetradecanoylphorbol Acetate

Topics: Alzheimer Disease; Animals; Animals, Newborn; Apolipoproteins E; Astrocytes; Bucladesine; Carbachol; Cell Survival; Cells, Cultured; Clonidine; Cyclic AMP; Drug Interactions; Hippocampus; Immunohistochemistry; Isoproterenol; Nerve Growth Factor; Norepinephrine; Protein Kinase C; Rats; Rats, Wistar; RNA, Messenger; Serotonin; Tetradecanoylphorbol Acetate; Tretinoin

Topics: Adrenal Gland Neoplasms; Alzheimer Disease; Amyloid; Amyloid beta-Protein Precursor; Animals; Cell Line; Ethers, Cyclic; Humans; Kinetics; Methionine; Molecular Weight; Okadaic Acid; Pheochromocytoma; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Biosynthesis; Protein Kinase C; Protein Precursors; Protein Processing, Post-Translational; Tetradecanoylphorbol Acetate; Transcription, Genetic