tetradecanoylphorbol acetate has been researched along with Acute Promyelocytic Leukemia in 268 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 37 (13.81) | 18.7374 |
| 1990's | 214 (79.85) | 18.2507 |
| 2000's | 9 (3.36) | 29.6817 |
| 2010's | 7 (2.61) | 24.3611 |
| 2020's | 1 (0.37) | 2.80 |
| Authors | Studies |
|---|---|
| Kawabata, H; Kawase, T; Masuki, H; Nakamura, M; Okubo, M; Sato, A; Tsujino, T; Uematsu, T; Watanabe, T | 1 |
| Amatori, S; Errico Provenzano, A; Fanelli, M; Gambarara, A; Mastrogiacomo, AR; Nasoni, MG; Persico, G; Russo, S | 1 |
| Dafre, AL; de Souza, LF; Hampton, MB; Meotti, FC; Pace, PE; Pearson, AG; Winterbourn, CC | 1 |
| Hosokawa, Y; Kashiwakura, I; Monzen, S; Takimura, K | 1 |
| Antica, M; Grcevic, D; Kardum-Skelin, I; Matulic, M; Radic-Kristo, D; Skelin, J | 1 |
| Duyster, J; Engelhardt, M; Ewerth, D; Greil, C; Hein, M; Kvainickas, A; Schmidts, A; Schnerch, D; Wäsch, R | 1 |
| Bártová, E; Hájek, R; Harnicarová, A; Kozubek, S; Krejcí, J; Kůrová, J; Legartová, S; Uhlírová, R | 1 |
| Bertagnolo, V; Bonora, M; Brugnoli, F; Capitani, S; Grassilli, S; Nika, E; Pinton, P | 1 |
| Fàbregas, P; Félez, J; Jardí, M; Miles, LA; Parmer, RJ | 1 |
| Geiszt, M; Ligeti, E; Nemet, K; Rada, BK; Roos, D; Van Bruggen, R | 1 |
| Cao, X; Chen, T; Han, C; Li, N; Wan, T; Yang, M | 1 |
| Benedyk, M; Dagher, MC; Doussiere, J; Kerkhoff, C; Nacken, W; Sopalla, C | 1 |
| Magnusson, KE; Navakauskiene, R; Pivoriunas, A; Savickiene, J; Treigyte, G | 1 |
| Cao, T; Dong, H; Han, B; Hua, F; Pan, H; Wei, W; Xu, C; Yang, T; Yang, Y | 1 |
| Bohnsack, JF; Chang, J | 1 |
| Chorváth, B; Duraj, J; Grófová, M; Hunáková, L; Sedlák, J | 1 |
| Andreeff, M; Collins, SJ; Drach, J; Engel, H; Malavasi, F; McQueen, T; Mehta, K; Robertson, KA | 1 |
| Berliner, N; Khanna-Gupta, A; Kolibaba, K; Zibello, TA | 1 |
| Agosti, V; Cimino, F; Cuomo, C; Esposito, F; Morra, F; Morrone, G; Russo, T; Venuta, S | 1 |
| Bacher, M; Kiefer, P; Pflüger, KH | 1 |
| Walters, JD; Wojcik, MS | 1 |
| Brown, G; Guest, SS; Johnson, WE; Jones, NA; Rowlands, DC; Williams, A | 1 |
| Cohen, IR; Eichstetter, I; Grässel, S; Iozzo, RV; Murdoch, AD | 1 |
| Nojima, S; Nojiri, H; Setaka, M; Suzuki, A; Suzuki, M; Yokoyama, K | 1 |
| An, NH; Han, MK; Kim, UH | 1 |
| Matsuhisa, T; Mori, Y | 1 |
| Fujita, J; Hashimoto, Y; Hata, Y; Nagai, M; Nakamura, H; Shiotani, T; Takahara, J; Yamaji, Y | 1 |
| Atkins, KB; Troen, BR | 1 |
| Heung, YM; Postle, AD | 2 |
| Malm, C; Walz, TM; Wasteson, A | 1 |
| Kajiyama, K; Katagiri, K; Katagiri, T; Yamamoto, T; Yoshida, T | 1 |
| Hoffman-Liebermann, B; Liebermann, DA; Nguyen, HQ | 1 |
| Brentani, MM; da Silva, MR; Federico, MH; Feldman, J; Katayama, ML; Koike, MA; Roela, RA; Sonohara, S | 1 |
| Bertrand, R; Jenkins, J; Pommier, Y; Solary, E | 1 |
| Drach, J; Malavasi, F; Mehta, K; Zhao, S | 1 |
| Hurme, M; Keski-Oja, J; Matikainen, S; Taipale, J | 1 |
| Minowada, G; Welch, W | 1 |
| Watts, RG | 1 |
| Brandt, TL; Fraser, DJ; Kroll, DJ | 1 |
| Wei, L; Yung, BY | 1 |
| Bhimani, RS; Frenkel, K; Schleifer, E; Troll, W; Zhong, Z | 1 |
| Varvayanis, S; Yen, A | 1 |
| Aubery, M; Derappe, C; Feugeas, JP; Néel, D; Pasqualetto, V | 1 |
| Chan, KF; Loh, TT; Lok, CN | 1 |
| Berry, JE; Khalkhali-Ellis, Z; Osdoby, P; Simpson, RU; Somerman, MJ | 2 |
| Jove, R; Nairn, R; Suchard, SJ; Yu, H | 1 |
| Aiello, A; Costa, A; Delia, D; Fontanella, E; Formelli, F; Miyashita, T; Pierotti, MA; Reed, JC | 1 |
| Hurme, M; Matikainen, S; Tapiovaara, H; Vaheri, A | 1 |
| Hakomori, S; Igarashi, Y; Masamune, A; Ohta, H; Sweeney, EA; Yatomi, Y | 1 |
| Banting, G; Chappell, JB; Henderson, LM | 1 |
| Collado-Escobar, D; Mollinedo, F; Pérez-Sala, D | 1 |
| Drexler, HG; Hu, ZB; Lanotte, M; Ma, W; Uphoff, CC | 1 |
| Collado-Escobar, D; Mollinedo, F | 1 |
| Bhatia, M; Kirkland, JB; Meckling-Gill, KA | 3 |
| Danishefsky, I; Whyzmuzis, CA; Wu, JM | 2 |
| Björnberg, F; Gullberg, U; Lantz, M; Olsson, I | 1 |
| Chada, S; Newburger, PE; Shen, Q; Whitney, C | 1 |
| Morimoto, K; Nakajima, M; Takeuchi, T | 1 |
| Kelloff, GJ; Sharma, S; Steele, VE; Stutzman, JD | 1 |
| Dimitrijevic, S; Evans, FJ; Gordge, PC; Ryves, WJ | 1 |
| Bürger, C; Müller, R; Wick, M | 1 |
| Larrick, JW; Wright, SC; Zhong, J | 1 |
| Ali, A; Ford-Hutchinson, AW; Nicholson, DW | 1 |
| Asaoka, Y; Nishizuka, Y; Tsujishita, Y | 1 |
| Nakamura, Y; Sakiyama, S; Takenaga, K | 1 |
| Coburn, JP; Eggleton, P; Ghebrehiwet, B; Sastry, KN; Tauber, AI; Zaner, KS | 1 |
| Dyer, KD; Lavigne, MC; Rosenberg, HF | 1 |
| Asaoka, Y; Nishizuka, Y; Sasaki, Y; Yoshida, K | 1 |
| Narayanan, R; Rosen, CA; Sartorelli, AC; Sokoloski, JA | 1 |
| Biskobing, DM; Nanes, MS; Rubin, J | 1 |
| Agranoff, AB; Betts, JC; Nabel, GJ; Shayman, JA | 1 |
| Hashimoto, Y; Iwasaki, S; Nishimura, K | 1 |
| Adachi, M; Hinoda, Y; Imai, K; Sekiya, M; Yachi, A | 1 |
| Cleary, ML; Naumovski, L | 1 |
| Hickson, ID; Hochhauser, D; Loflin, PT; Morales, F; Zwelling, LA | 1 |
| De Caterina, R; Giannessi, D; Paggiaro, PL; Parente, L; Sicari, R; Solito, E | 1 |
| Bertrand, R; Pommier, Y; Solary, E | 1 |
| Kolb, H; Petrides, PE; Ries, C | 1 |
| Gullberg, U; Lantz, M; Lindvall, L; Olsson, I; Persson, AM | 1 |
| Baldwin, GC; Golde, DW; Kitano, K; Rivas, CI; Vera, JC | 1 |
| Melloni, E; Passalacqua, M; Patrone, M; Pessino, A; Pontremoli, S; Sparatore, B | 1 |
| Bene, L; Nagy, K; Pásti, G; Zs-Nagy, I | 1 |
| Drexler, HG; Hu, ZB; Ma, W; Uphoff, CC | 1 |
| Macfarlane, DE; O'Donnell, PS | 1 |
| Kato, I; Morinaga, N; Noda, M | 1 |
| Carter, TH; Konno-Sato, S; Wu, JM | 1 |
| Datta, R; Huberman, E; Kharbanda, SM; Kufe, DW; Mizobuchi, T; Stone, RM; Yang, KD | 1 |
| Onoda, K; Yin, HL; Yu, FX | 1 |
| Mattera, R; McConnell, BK; Wilkins, PL; Xing, M | 1 |
| Dornand, J; Favero, J; Marti, J; Nicolas, M; Taimi, M | 1 |
| Gehring, U; Zeiner, M | 1 |
| al-Katib, A; Khilnani, S; Kohler, W; Mohammad, R; Mutchnick, MG; Nath, R; Silverman, A; Smith, MR; Szabo, P | 1 |
| Arrigo, AP; Levine, H; Nadler, LM; Ryan, C; Samson, W; Spector, NL | 1 |
| Belpomme, D; Calabresse, C; Chomienne, C; Ronco, G; Venturini, L; Villa, P | 1 |
| Bertrand, R; Kohn, KW; Pommier, Y; Solary, E | 1 |
| Datta, R; Kufe, DW; Qureshi, SA; Sukhatme, VP; Taneja, N; Weichselbaum, R | 1 |
| Cardellini, E; Durban, E | 1 |
| Kobayashi, K; Kuno, T; Morita, K; Nagao, M; Nishikawa, M; Omay, SB; Shima, H; Tanaka, C; Tawara, I; Toyoda, H | 1 |
| Berk, BC; Pouysségur, J; Rao, GN; Sardet, C | 1 |
| Fiore, S; Reardon, EM; Romano, M; Serhan, CN | 1 |
| Kharbanda, S; Kufe, DW; Saleem, A; Slapak, CA | 1 |
| Hino, M; Inaba, M; Koyama, H; Morii, H; Nishino, T; Nishizawa, Y; Okuno, S; Terada, M | 1 |
| Kosaka, H; Morimoto, K; Shiga, T; Takeuchi, T | 1 |
| Maresh, GA; Monnat, RJ | 1 |
| Hamilton, JA; Vairo, G | 1 |
| Christman, JK; Nangia-Makker, P; Ochieng, J; Raz, A | 1 |
| Alcaín, FJ; Burón, MI; González-Reyes, JA; Navarro, F; Navas, P; Rodríguez-Aguilera, JC; Villalba, JM | 1 |
| Chang, ZF; Huang, DY | 1 |
| Cannon, PM; Feinberg, MB; Kim, S; Shin, HS; Tenen, DG | 1 |
| Biskobing, DM; Rubin, J | 1 |
| Goerig, M; Habenicht, AJ; Nüsing, R; Ullrich, V | 1 |
| Chambers, TC; Chiou, SH; Kuo, JF; Raynor, RL; Zheng, B | 1 |
| Henning-Chubb, C; Huberman, E; Kiguchi, K | 1 |
| Boulay, F; Brouchon, L; Mery, L; Tardif, M | 1 |
| Colgan, SP; Delp, C; Gillece-Castro, B; Madara, JL; Mrsny, RJ; Parkos, CA; Patapoff, TW | 1 |
| Bustin, M; Lian, JB; Owen, TA; Shakoori, AR; Shalhoub, V; Stein, GS; Stein, JL | 1 |
| Kasuga, M; Konda, Y; Matozaki, S; Matozaki, T; Matsuda, K; Nakano, O; Sakamoto, C; Suzuki, T; Uchida, T; Wada, K | 1 |
| Iizuku, T; Isogai, Y; Osada, H; Tanaka, K; Tsuyama, T | 1 |
| Alvarez, M; Blagosklonny, MV; Fojo, A; Neckers, LM | 1 |
| Kuhajda, FP; Pasternack, GR; Pizer, ES; Wood, FD | 1 |
| Antochi, R; Berry, DM; Bhatia, M; Meckling-Gill, KA | 1 |
| Gambacorti-Passerini, C; Garattini, E; Giannì, M; Rambaldi, A; Terao, M | 1 |
| Adams, PD; Kiley, SC; Parker, PJ | 1 |
| Kiley, SC; Parker, PJ | 1 |
| Koshimizu, K; Kuki, W; Murakami, A; Nakamura, Y; Ohigashi, H; Ohto, Y; Takahashi, Y; Yonei, H | 1 |
| Brown, DC; Larson, RS; Sklar, LA | 1 |
| Albanell, J; Allopenna, J; Dmitrovsky, E; Maerz, W; Martin, P; Moore, MA; Nason-Burchenal, K | 1 |
| Gonzalez-Christen, J; Grégoire, C; Le Cabec, V; Maridonneau-Parini, I; N'Diaye, EN; Vaissiere, C | 1 |
| Alexandrov, IA; Blagosklonny, MV; Mushinski, JF; Nordan, RP; Romanova, LY | 1 |
| Nakano, K; Suzuki, M | 1 |
| Norman, AW; Song, X | 1 |
| Chao, CY; Shaio, MF; Yang, KD | 1 |
| Ismair, MG; Kolb, HJ; Lottspeich, F; Petrides, PE; Ries, C; Zang, C | 1 |
| Chubb, CB; Collart, FR; Huberman, E; Laouar, A; Xie, B | 1 |
| Norman, AW; Song, XD | 1 |
| Bredoux, R; Bruel, A; Chomienne, C; Enouf, J; Gélébart, P; Giannì, M; Kovàcs, T; Launay, S; Papp, B; Zassadowski, F | 1 |
| Nilsson, K; Oberg, F; Siegbahn, A; Tenno, T | 1 |
| Engdahl, WR; Gauger, JR; Loberg, LI; McCormick, DL | 1 |
| Arai, K; Ito, E; Katsuoka, F; Komatsu, N; Terui, K; Toki, T; Yamamoto, M; Yokoyama, M | 1 |
| Berry, DM; Clark, CS; Meckling-Gill, KA | 1 |
| Bokoch, GM; Prossnitz, V | 1 |
| Brakebusch, C; Engelmann, H; Holtmann, H; Kemper, O; Nophar, Y; Resch, K; Wallach, D; Winzen, R | 1 |
| Niiya, K; Sakuragawa, N | 1 |
| Ganser, A; Herrmann, F; Lübbert, M; Ludwig, WD; Mertelsmann, R; Oster, W | 1 |
| Eisenman, RN; Whyte, P | 1 |
| Ban, J; Weber, G | 1 |
| Levy, R; Rosmarin, AG; Tenen, DG | 1 |
| Lu, X; Seligy, VL | 1 |
| Baserga, R; Pietrzkowski, Z; Porcu, P; Reiss, K; Sell, C | 1 |
| Brent, LH; Chou, RH; Gong, QH; Wieland, SJ | 1 |
| Figdor, CG; Gendron, MC; Hogervorst, F; Lanotte, M; Martin-Thouvenin, V | 1 |
| Cook, PP; Garris, TO; Messer, BR; Parker, PJ; Qin, W; Ways, DK | 1 |
| Goldenberg, NA; Kolla, SS; Studzinski, GP; Xu, HM | 1 |
| Gu, J; Nakamura, M; Nishikawa, A; Saito, M; Sakoe, K; Taniguchi, N; Tsunoda, A | 1 |
| Collart, FR; Horio, M; Huberman, E; Tonetti, DA | 1 |
| Berliner, N; Devarajan, P; Ginsberg, SS; Johnston, JJ; Van Wart, HE | 1 |
| Hibbs, MS | 1 |
| Awtrey, CS; Colgan, SP; Delp, C; Madara, JL; Matthews, JB; Parkos, CA | 1 |
| Begin, ME; Das, UN; Ells, G | 1 |
| Collard, JF; Raymond, Y; Senécal, JL | 1 |
| Datta, R; Hallahan, DE; Huberman, E; Kharbanda, SM; Kufe, DW; Rubin, E; Sherman, ML; Weichselbaum, RR | 1 |
| Brautigan, DL; Buzzi, M; Fast, LD; Frackelton, AR; Lombardi, AJ; Lu, L; Posner, MR | 1 |
| Julien, M; Paulin-Levasseur, M | 1 |
| Brown, G; Jones, NA; Lord, JM | 1 |
| Fujiwara, C; Mochizuki, N; Oda, T; Ohta, M; Sagara, J; Shimizu, N; Utiyama, H | 1 |
| Kan, CC; Kolesnick, RN | 1 |
| Mason, SN; Weinberg, JB; Wortham, TS | 1 |
| Hoffman, DR; Snyder, F; Thomas, VL | 1 |
| Borelli, TJ; Chang, CC; Williams, BR; Wu, JM | 1 |
| Alonso, MA; Fresno, M; Lopez-Guerrero, JA; Pimentel-Muiños, FX | 1 |
| Chen, T; Friis, RR; Meier, RW; Tobler, A | 1 |
| Hruska, KA; Malone, JD; Nishii, Y; Seino, Y; Tanaka, H; Teitelbaum, SL | 1 |
| Ishihara, H; Shikita, M; Takeuchi, K; Tsuneoka, K | 1 |
| Berger, M; Cowen, DS; Dubyak, GR; Nuttle, L | 1 |
| Ahmed, N; Weidemann, MJ; Williams, JF | 1 |
| Burn, TC; Pahl, HL; Tenen, DG | 1 |
| Hilger, RA; Kasimir, S; König, W; Schönfeld, W | 1 |
| Boquet, P; Bourmeyster, N; Jouan, A; Stasia, MJ; Vignais, PV | 1 |
| Kato, Y; Ogawa, K; Okuda, T; Okuma, M; Sawada, H; Tashima, M; Yumoto, Y | 1 |
| Chorváth, B; Fuchsberger, N; Sedlák, J | 1 |
| Brown, G; Bunce, CM; Creba, JA; French, PJ; Lord, JM; McConnell, FM; Michell, RH; Stephens, LR | 1 |
| Cho-Chung, YS; Clair, T; Tortora, G | 1 |
| Bevilacqua, MP; Bliss, GA; Geng, JG; Kim, JM; McEver, RP; McIntyre, TM; Moore, KL; Prescott, SM; Zimmerman, GA | 1 |
| Eto, Y; Miyamoto, K; Ogata, E; Shibai, H; Takahashi, S; Yamashita, T | 1 |
| Berkovic, D; Doenecke, D; Eibl, H; Hochhuth, C; Unger, C | 1 |
| Gullberg, U; Lantz, M; Lindvall, L; Olsson, I | 1 |
| Kaise, N; Masui, Y; Nishida, T; Nishino, N; Nishino, T; Sindo, Y; Yasuda, S | 1 |
| Aigner, L; Brockhaus, M; Hohmann, HP; Remy, R; van Loon, AP | 1 |
| Kalf, GF; Oliveira, NL | 1 |
| Aihara, H; Asaoka, Y; Nishizuka, Y; Yoshida, K | 1 |
| Hayashi, T; Kobayashi, M; Miyoshi, I; Niiya, K; Sakuragawa, N; Takeuchi, T | 1 |
| Hannun, Y; Kim, MY; Linardic, C; Obeid, L | 1 |
| Etoh, S; Hatase, O; Irino, S; Itano, T; Matsui, H; Miyamoto, O; Nishio, H; Taoka, T; Tasaka, T; Tokuda, M | 1 |
| Cayre, YE; O'Driscoll, K; Solomon, DH; Sosne, G; Weinstein, IB | 1 |
| Chen, ZX; Wu, WL | 1 |
| Baxter, MA; Brown, G; Bunce, CM; French, PJ; Grafton, G; Jones, NA; Lord, JM; Michell, RH | 1 |
| Baxter, MA; Brown, G; Bunce, CM; Grafton, G; Lord, JM; Michell, RH | 1 |
| Gaynor, R; Koeffler, P; Simon, K | 1 |
| Tai, HH; Tian, ZG; Xun, CQ | 1 |
| Bacon, TA; Wickstrom, E | 1 |
| Cho-Chung, YS; Clair, T; Pepe, S; Tortora, G; Yokozaki, H | 1 |
| Handschumacher, RE; Lee, CW; Sartorelli, AC; Sokoloski, JA | 1 |
| Eibl, H; Fleer, EA; Kuo, JF; Raynor, RL; Shoji, M; Vogler, WR | 1 |
| Grant, DA; Sharma, RJ | 1 |
| Bernstein, SH; Datta, R; Kufe, DW; Sherman, ML; Stone, RM | 1 |
| Bonvini, E; DeBell, KE; Hoffman, T; Ponzoni, M | 1 |
| Han, KK; Wu, J; Zhu, DX; Zhu, JQ | 1 |
| Kinkade, JM; Merrill, AH; Owens, NE; Stevens, VL; Winton, EF | 1 |
| Chap, H; Lumb, RH; Pool, GL; Record, M; Ribbes, G; Terce, F | 1 |
| Aarbakke, J; Bang, BE; Moens, U | 1 |
| Hurme, M; Ronni, T; Serkkola, E; Silvennoinen, O | 1 |
| Honda, A; Needleman, P; Raz, A | 1 |
| Fauci, AS; Folks, TM; Kinter, AL; Maury, W; Poli, G | 1 |
| Gewirtz, AM; Shen, YM | 1 |
| Facy, P; Hubert, J; Hubert, M; Monsigny, M; Seve, AP | 1 |
| Barnea, E; Levy, R; Shany, S; Zimlichman, R | 1 |
| Arcuri, RA; De Souza, MH; Marques-Silva, VM; Rumjanek, VM; Teixeira, MC | 1 |
| Oliver, CN | 1 |
| French, BT; Grever, MR; Patrick, DE; Trewyn, RW | 1 |
| Busch, H; Jhiang, SM; Yaneva, M | 1 |
| Birnie, GD; Jamieson, T; Neill, R; Vass, JK | 1 |
| Hannun, YA; Karolak, LA; Obeid, LM; Okazaki, T | 1 |
| Hashimoto, Y; Shudo, K | 1 |
| Akiyama, T; Toyoshima, K | 1 |
| Chang, ZF | 1 |
| Andersson, M; Bergstrand, H; Olsson, H; Oredsson, SM | 1 |
| Jungblut, P; Schultz, G; Seifert, R | 1 |
| Aller, P; Rius, C | 1 |
| Horiguchi, J; Imamura, K; Kufe, D; Luebbers, R; Spriggs, D; Stone, R | 1 |
| Billah, MM; Egan, RW; Mullmann, TJ; Pai, JK; Siegel, MI | 1 |
| Chen, ZX; Wang, W; Wu, WL | 1 |
| Arndt, AD; Gohill, J; Hart, DA; Houwen, B; Rankin, K | 1 |
| Hazav, P; Levy, R; Moran, A; Shany, S | 1 |
| Nath, J; Powledge, A; Wright, DG | 1 |
| Constantinou, A; Henning-Chubb, C; Huberman, E | 1 |
| Kolesnick, RN | 1 |
| Cross, SM; Gorsky, LD; Morin, MJ | 1 |
| Cockcroft, S; Geny, B; Stutchfield, J | 1 |
| Akiyama, Y; Kiriyama, Y; Kitoh, T; Kubota, M; Mikawa, H; Takimoto, T; Tanizawa, A | 1 |
| Bungo, M; Fujita, J; Futami, H; Hashimoto, Y; Irino, S; Nakamura, H; Shiotani, T; Tanaka, T; Yamaji, Y; Yamauchi, N | 1 |
| Huijgens, PC; Langenhuijsen, MM; Ossenkoppele, GJ; Rebel, VI; Wijermans, PW | 1 |
| Bacon, TA; Gonzalez, A; Lyman, GH; Wickstrom, E; Wickstrom, EL | 1 |
| Denhardt, DT; Kowalski, J | 1 |
| Reisman, D; Rotter, V | 1 |
| Cadwell, FJ; Gailani, D; Hromas, RA; Macfarlane, DE; O'Donnell, PS | 1 |
| Hsu, T; Simpson, RU; Taylor, JM; Wendt, MD | 1 |
| Giese, G; Paulin-Levasseur, M; Scherbarth, A; Traub, P | 1 |
| Beardsley, GP; Sartorelli, AC; Sokoloski, JA | 1 |
| Kinkade, JM; Merrill, AH; Owens, NE; Smith, EE; Stevens, VL; Winton, EF | 1 |
| Kuroki, T; Nose, K; Saito, H | 1 |
| Komada, F; Nishikawa, M; Shirakawa, S; Uemura, Y | 1 |
| Knauf, PA; Kozody, DJ; Restrepo, D | 1 |
| Damais, C; Frelin, C; Krawice, I; Ladoux, A | 1 |
| Auwerx, JH; Chait, A; Deeb, SS; Wolfbauer, G | 1 |
| Blick, M; Chan, D; Hinds, M; Mayes, J; Silberman, LE; Zwelling, LA | 1 |
| Cowen, DS; Dubyak, GR; Meuller, LM | 1 |
| Cotter, TG; Meagher, LC | 1 |
| Hall, ER; Sanduja, SK; Trial, J | 1 |
| Bar-Tana, R; Fibach, E; Fuks, Z; Vlodavsky, I; Yahalom, J | 1 |
| Courcoul, M; Dubreuil, P; Mannoni, P | 1 |
| Hanke, T; Harley, CB; Tyers, M | 1 |
| Berdel, WE; Kuo, JF; Raynor, RL; Shoji, M; Vogler, WR | 1 |
| Pályi, I | 1 |
2 review(s) available for tetradecanoylphorbol acetate and Acute Promyelocytic Leukemia
| Article | Year |
|---|---|
Reciprocal alterations of enzymic phenotype of purine and pyrimidine metabolism in induced differentiation of leukemia cells.
Topics: Cell Cycle; Cell Differentiation; Cell Line; Dimethyl Sulfoxide; GMP Reductase; Humans; IMP Dehydrogenase; Leukemia, Promyelocytic, Acute; NADH, NADPH Oxidoreductases; Phenotype; Purines; Pyrimidines; Tetradecanoylphorbol Acetate; Thymidine; Tretinoin; Tumor Cells, Cultured | 1994 |
Protein phosphorylation events and changes in inositol metabolism during HL60 cell differentiation.
Topics: Cell Differentiation; Cell Line; Humans; Inositol; Leukemia, Promyelocytic, Acute; Monocytes; Neoplasm Proteins; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate | 1991 |
266 other study(ies) available for tetradecanoylphorbol acetate and Acute Promyelocytic Leukemia
| Article | Year |
|---|---|
Responses of promyelocytic leukemia HL60 cells as an inflammatory cell lineage model to silica microparticles used to coat blood collection tubes.
Topics: Animals; Cell Lineage; Dimethyl Sulfoxide; HL-60 Cells; Humans; Inflammation; Leukemia, Promyelocytic, Acute; Mice; Plastics; Silicon Dioxide; Superoxide Dismutase; Tetradecanoylphorbol Acetate | 2022 |
Effects of Fifty-Hertz Electromagnetic Fields on Granulocytic Differentiation of ATRA-Treated Acute Promyelocytic Leukemia NB4 Cells.
Topics: Bone Marrow Cells; Cell Differentiation; Cell Line; Cell Proliferation; Electromagnetic Fields; Humans; Leukemia, Promyelocytic, Acute; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Tretinoin | 2018 |
Peroxiredoxin expression and redox status in neutrophils and HL-60 cells.
Topics: Antioxidants; Gene Expression Regulation, Neoplastic; HL-60 Cells; Homeodomain Proteins; Humans; Leukemia, Promyelocytic, Acute; Neutrophils; Onium Compounds; Oxidants; Oxidation-Reduction; Signal Transduction; Staphylococcus aureus; Tetradecanoylphorbol Acetate | 2019 |
Acute promyelocytic leukemia mutated to radioresistance suppressed monocyte lineage differentiation by phorbol 12-myristate 13-acetate.
Topics: Antineoplastic Agents; Biomarkers, Tumor; Carcinogens; Cell Differentiation; Cell Lineage; Flow Cytometry; Gene Expression Profiling; HL-60 Cells; Humans; Leukemia, Promyelocytic, Acute; Monocytes; Mutation; Oligonucleotide Array Sequence Analysis; Radiation Tolerance; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured; X-Rays | 2013 |
Notch affects the prodifferentiating effect of retinoic acid and PMA on leukemic cells.
Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Cell Differentiation; Cell Line, Tumor; Cell Lineage; Cell Proliferation; Granulocyte Precursor Cells; HL-60 Cells; Homeodomain Proteins; Humans; Jurkat Cells; Leukemia, Promyelocytic, Acute; Mice; Myeloid Cells; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Receptor, Notch1; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factor HES-1; Tretinoin; U937 Cells | 2015 |
Suppression of APC/CCdh1 has subtype specific biological effects in acute myeloid leukemia.
Topics: Adult; Aged; Aged, 80 and over; Antigens, CD; Cadherins; Cell Cycle Checkpoints; Cell Differentiation; Female; Gene Knockdown Techniques; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Tetradecanoylphorbol Acetate; Tretinoin; Young Adult | 2016 |
Nuclear organization of PML bodies in leukaemic and multiple myeloma cells.
Topics: Cell Cycle; Cell Differentiation; Cell Line, Tumor; Cell Nucleus; Flow Cytometry; Gamma Rays; HL-60 Cells; Humans; Intranuclear Inclusion Bodies; K562 Cells; Leukemia, Promyelocytic, Acute; Melphalan; Multiple Myeloma; Tetradecanoylphorbol Acetate; Tretinoin; U937 Cells | 2008 |
Vav1 is a crucial molecule in monocytic/macrophagic differentiation of myeloid leukemia-derived cells.
Topics: Actins; Cell Adhesion; Cell Differentiation; Cell Line, Tumor; Cell Nucleus Shape; Cell Shape; Cytoskeleton; Gene Silencing; Humans; Leukemia, Promyelocytic, Acute; Macrophages; Monocytes; Phenotype; Phosphorylation; Phosphotyrosine; Proto-Oncogene Proteins c-vav; Tetradecanoylphorbol Acetate; Up-Regulation | 2011 |
Monoclonal antibodies against receptor-induced binding sites detect cell-bound plasminogen in blood.
Topics: Antibodies, Monoclonal; Antibody Specificity; Binding Sites; Carcinogens; Erythrocytes; Flow Cytometry; Humans; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Lipopolysaccharides; Lymphocytes; Monocytes; Neutrophils; Plasminogen; Radioligand Assay; Tetradecanoylphorbol Acetate | 2012 |
Calcium signalling is altered in myeloid cells with a deficiency in NADPH oxidase activity.
Topics: Calcium; Calcium Signaling; Cell Line; Cells, Cultured; Enzyme Inhibitors; Granulomatous Disease, Chronic; Humans; Leukemia, Promyelocytic, Acute; Manganese; Membrane Potentials; Myeloid Cells; NADPH Oxidases; Neutrophils; Nitric Oxide Synthase; Onium Compounds; Superoxides; Tetradecanoylphorbol Acetate | 2003 |
Rab7b, a novel lysosome-associated small GTPase, is involved in monocytic differentiation of human acute promyelocytic leukemia cells.
Topics: Amino Acid Sequence; Cell Differentiation; Cell Line, Tumor; Cells, Cultured; Dendritic Cells; Gene Expression; Humans; Leukemia, Promyelocytic, Acute; Lysosomes; Molecular Sequence Data; Monocytes; rab GTP-Binding Proteins; Recombinant Fusion Proteins; RNA, Messenger; Sequence Alignment; Subcellular Fractions; Tetradecanoylphorbol Acetate; Tissue Distribution; Up-Regulation | 2004 |
The arachidonic acid-binding protein S100A8/A9 promotes NADPH oxidase activation by interaction with p67phox and Rac-2.
Topics: Animals; Arachidonic Acid; Calgranulin A; Calgranulin B; Cattle; Cell Line, Tumor; Cell-Free System; Enzyme Activation; Gene Expression; Gene Silencing; Humans; Leukemia, Promyelocytic, Acute; Mice; Mice, Knockout; NADPH Oxidases; Neutrophils; Oligonucleotides, Antisense; Phosphoproteins; Polymerase Chain Reaction; rac GTP-Binding Proteins; RAC2 GTP-Binding Protein; Reactive Oxygen Species; Recombinant Fusion Proteins; Respiratory Burst; RNA, Messenger; Superoxides; Tetradecanoylphorbol Acetate | 2005 |
Sp1 and NF-kappaB transcription factor activity in the regulation of the p21 and FasL promoters during promyelocytic leukemia cell monocytic differentiation and its associated apoptosis.
Topics: Apoptosis; Blotting, Western; Cell Differentiation; Electrophoretic Mobility Shift Assay; Fas Ligand Protein; HL-60 Cells; Humans; Leukemia, Promyelocytic, Acute; Membrane Glycoproteins; Monocytes; NF-kappa B; Oncogene Protein p21(ras); Promoter Regions, Genetic; Sp1 Transcription Factor; Tetradecanoylphorbol Acetate | 2004 |
Requirement for ERK activity in sodium selenite-induced apoptosis of acute promyelocytic leukemia-derived NB4 cells.
Topics: Apoptosis; Dose-Response Relationship, Drug; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Humans; JNK Mitogen-Activated Protein Kinases; Leukemia, Promyelocytic, Acute; Mitogen-Activated Protein Kinase Kinases; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Sodium Selenite; Tetradecanoylphorbol Acetate; Time Factors | 2007 |
Activation of beta 1 integrin fibronectin receptors on HL60 cells after granulocytic differentiation.
Topics: Animals; Cell Adhesion; Cell Differentiation; Dimethyl Sulfoxide; Granulocytes; Humans; Integrin beta1; Integrins; Leukemia, Promyelocytic, Acute; Rats; Receptors, Fibronectin; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Modulation of protectin (CD59 antigen) cell surface expression on human neoplastic cell lines.
Topics: Antigens, CD; Breast Neoplasms; Calcitriol; Carcinoma; CD59 Antigens; Cell Membrane; Cytokines; Down-Regulation; Electrophoresis, Polyacrylamide Gel; Female; Flow Cytometry; Fluorescent Antibody Technique; Glioma; Humans; Leukemia, Myeloid; Leukemia, Promyelocytic, Acute; Membrane Glycoproteins; Ovarian Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured; Up-Regulation | 1993 |
Retinoic acid-induced expression of CD38 antigen in myeloid cells is mediated through retinoic acid receptor-alpha.
Topics: ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Antigens, CD; Antigens, Differentiation; Bone Marrow; Cell Differentiation; Cell Line; Clone Cells; Dose-Response Relationship, Drug; Drug Resistance; Flow Cytometry; Gene Expression; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Granulocytes; Hematopoietic Stem Cells; Humans; Interferon-gamma; Kinetics; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Promyelocytic, Acute; Membrane Glycoproteins; Receptors, Retinoic Acid; Recombinant Proteins; Tetradecanoylphorbol Acetate; Transfection; Tretinoin; Tumor Cells, Cultured | 1994 |
NB4 cells show bilineage potential and an aberrant pattern of neutrophil secondary granule protein gene expression.
Topics: Antigens, CD; Collagenases; Cytoplasmic Granules; Gene Expression Regulation, Leukemic; Granulocyte Colony-Stimulating Factor; Humans; Lactoferrin; Leukemia, Promyelocytic, Acute; Matrix Metalloproteinase 9; Peroxidase; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-myc; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1994 |
Inhibition of the differentiation of human myeloid cell lines by redox changes induced through glutathione depletion.
Topics: Antigens, CD; Antigens, CD34; Base Sequence; Cell Adhesion; Cell Differentiation; DNA-Binding Proteins; Early Growth Response Protein 1; Glutathione; Granulocytes; Humans; Immediate-Early Proteins; Leukemia, Erythroblastic, Acute; Leukemia, Promyelocytic, Acute; Maleates; Molecular Sequence Data; Oxidation-Reduction; Peroxidase; Phenotype; Proto-Oncogene Proteins c-jun; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription Factors; Tumor Cells, Cultured | 1994 |
Relationship of calcitonin mRNA expression to the differentiation state of HL 60 cells.
Topics: Acetamides; Calcitonin; Calcitonin Gene-Related Peptide; Cell Differentiation; Cell Division; Cholecalciferol; Dimethyl Sulfoxide; Gene Expression; Humans; Leukemia, Promyelocytic, Acute; Macrophages; Models, Biological; Monocytes; Phenotype; RNA, Messenger; Staining and Labeling; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Polyamine transport in human promyelocytic leukemia cells and polymorphonuclear leukocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Biological Transport; Cell Line; Genistein; Gramicidin; Humans; In Vitro Techniques; Ionomycin; Isoflavones; Isoquinolines; Kinetics; Leukemia, Promyelocytic, Acute; Neutrophils; Piperazines; Protein Kinase Inhibitors; Putrescine; Spermidine; Spermine; Sulfonamides; Temperature; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Down-regulation but not phosphorylation of stathmin is associated with induction of HL60 cell growth arrest and differentiation by physiological agents.
Topics: Blotting, Western; Calcitriol; Cell Differentiation; Cell Division; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Promyelocytic, Acute; Microtubule Proteins; Monocytes; Neutrophils; Phosphoproteins; Phosphorylation; Stathmin; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
The proteoglycan perlecan is expressed in the erythroleukemia cell line K562 and is upregulated by sodium butyrate and phorbol ester.
Topics: Base Sequence; Butyrates; Butyric Acid; Cell Differentiation; Chondroitinases and Chondroitin Lyases; Glyceraldehyde-3-Phosphate Dehydrogenases; Heparan Sulfate Proteoglycans; Heparitin Sulfate; Humans; Immunoblotting; Leukemia, Erythroblastic, Acute; Leukemia, Promyelocytic, Acute; Molecular Sequence Data; Polysaccharide-Lyases; Proteoglycans; RNA; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Up-Regulation | 1995 |
Clear differences in ceramide metabolism between glycosphingolipids and sphingomyelin in a human promyelocytic leukemia cell line HL-60 stimulated by a differentiation inducer.
Topics: Cell Differentiation; Ceramides; Chromatography, Gas; Chromatography, Thin Layer; Glycosphingolipids; Humans; Leukemia, Promyelocytic, Acute; Spectrometry, Mass, Fast Atom Bombardment; Sphingomyelins; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Expression of glycosylphosphatidylinositol-anchored NAD glycohydrolase in differentiated HL60 cells by phorbol ester.
Topics: ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Antigens, CD; Antigens, Differentiation; Cell Differentiation; Cell Membrane; Glycosylphosphatidylinositols; Humans; Leukemia, Promyelocytic, Acute; Membrane Glycoproteins; N-Glycosyl Hydrolases; NAD+ Nucleosidase; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1995 |
Mode of differentiation of human promyelocytic leukemia cell line, HL-60, by 1 alpha,25-dihydroxyvitamin D3.
Topics: Calcitriol; Cell Differentiation; Dose-Response Relationship, Drug; Humans; Leukemia, Promyelocytic, Acute; Mitosis; Neoplastic Stem Cells; Nitroblue Tetrazolium; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Comparative responsiveness of HL-60, HL-60R, and HL-60R+ (LRARSN) cells to retinoic acid, calcitriol, 9 cis-retinoic acid, and sodium butyrate.
Topics: Butyrates; Butyric Acid; Calcitriol; Cathepsin D; Cathepsin L; Cathepsins; Cell Differentiation; Cysteine Endopeptidases; Drug Resistance; Endopeptidases; Gene Expression; Humans; Interleukin-8; Leukemia, Promyelocytic, Acute; RNA, Messenger; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1995 |
Synthesis of phosphatidyl[3H]butanol molecular species by phospholipase D in HL60 granulocytes.
Topics: Animals; Butanols; Cell Differentiation; Cell Line; Chromatography, High Pressure Liquid; Glycerophospholipids; Granulocytes; Humans; Leukemia, Promyelocytic, Acute; Liver; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipase D; Radioisotope Dilution Technique; Rats; Tetradecanoylphorbol Acetate; Tretinoin; Tritium; Tumor Cells, Cultured | 1995 |
Substrate selectivity of phospholipase D in HL60 granulocytes: effects of fatty acid supplementation.
Topics: Butanols; Cell Differentiation; Cell Line; Chromatography, High Pressure Liquid; Fatty Acids; Glycerophospholipids; Granulocytes; Humans; Leukemia, Promyelocytic, Acute; Phosphatidic Acids; Phosphatidylcholines; Phospholipase D; Substrate Specificity; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1995 |
Expression of the transforming growth factor alpha protooncogene in differentiating human promyelocytic leukemia (HL-60) cells.
Topics: Cell Differentiation; Gene Expression; Granulocytes; Humans; Leukemia, Promyelocytic, Acute; Macrophages; Monocytes; Proto-Oncogenes; RNA; Tetradecanoylphorbol Acetate; Time Factors; Transcription, Genetic; Transforming Growth Factor alpha; Tumor Cells, Cultured | 1993 |
Tyrosine-phosphorylation of tubulin during monocytic differentiation of HL-60 cells.
Topics: Cell Differentiation; Humans; Leukemia, Promyelocytic, Acute; Monocytes; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fyn; Proto-Oncogene Proteins pp60(c-src); Tetradecanoylphorbol Acetate; Tubulin; Tumor Cells, Cultured; Tyrosine | 1993 |
The zinc finger transcription factor Egr-1 is essential for and restricts differentiation along the macrophage lineage.
Topics: Animals; Base Sequence; Binding Sites; Bone Marrow; Bone Marrow Cells; Cell Differentiation; Cell Nucleus; Dimethyl Sulfoxide; DNA-Binding Proteins; DNA, Neoplasm; Early Growth Response Protein 1; Gene Expression; Granulocytes; Hematopoietic Stem Cells; Humans; Immediate-Early Proteins; Leukemia, Promyelocytic, Acute; Macrophages; Mice; Mice, Inbred Strains; Molecular Sequence Data; Oligonucleotides, Antisense; Poly A; RNA; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription Factors; Transcription, Genetic; Transfection; Tumor Cells, Cultured; Zinc Fingers | 1993 |
Vitamin D3 binding activity during leukemic cell differentiation.
Topics: Calcitriol; Cell Differentiation; Humans; Interferons; Leukemia, Promyelocytic, Acute; Receptors, Calcitriol; Receptors, Steroid; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1993 |
Apoptosis and its modulation in human promyelocytic HL-60 cells treated with DNA topoisomerase I and II inhibitors.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Aminoquinolines; Aphidicolin; Apoptosis; Benzamides; Calcium; Calmodulin; Camptothecin; Cell Cycle; Chromatin; Cyclosporine; DNA; Egtazic Acid; Ethers, Cyclic; Humans; Isoquinolines; Leukemia, Experimental; Leukemia, Promyelocytic, Acute; Microscopy, Electron; Naphthalenes; Okadaic Acid; Phosphoprotein Phosphatases; Piperazines; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerase Inhibitors; Polycyclic Compounds; Protein Kinase C; Spermine; Staurosporine; Teniposide; Tetradecanoylphorbol Acetate; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Cells, Cultured; Zinc | 1993 |
Rapid induction of CD38 antigen on myeloid leukemia cells by all trans-retinoic acid.
Topics: ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Antigens, CD; Antigens, Differentiation; Cells, Cultured; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Dose-Response Relationship, Drug; Gene Expression; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Granulocytes; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Membrane Glycoproteins; Monocytes; Recombinant Proteins; Reference Values; Tetradecanoylphorbol Acetate; Translocation, Genetic; Tretinoin; Tumor Cells, Cultured | 1993 |
Induction of transforming growth factor beta 1 and its receptor expression during myeloid leukemia cell differentiation.
Topics: Amino Acid Sequence; Animals; Antibodies; Base Sequence; Cell Differentiation; Cell Line; Cloning, Molecular; DNA Primers; Fibrosarcoma; Gene Expression; Humans; Kinetics; Leukemia, Myeloid; Leukemia, Promyelocytic, Acute; Lung; Mink; Molecular Sequence Data; Polymerase Chain Reaction; Receptors, Transforming Growth Factor beta; Recombinant Fusion Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Transforming Growth Factor beta; Tretinoin; Tumor Cells, Cultured | 1994 |
Variation in the expression and/or phosphorylation of the human low molecular weight stress protein during in vitro cell differentiation.
Topics: Actins; Animals; Arsenites; Cell Differentiation; Cell Line; Cytoskeleton; Drosophila; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Gene Expression; Granulocytes; Heat-Shock Proteins; Hot Temperature; HSP30 Heat-Shock Proteins; Humans; Kinetics; Leucine; Leukemia, Erythroblastic, Acute; Leukemia, Promyelocytic, Acute; Megakaryocytes; Membrane Proteins; Mice; Molecular Weight; Phosphates; Phosphorylation; Sodium Compounds; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Role of gelsolin in the formation and organization of triton-soluble F-actin during myeloid differentiation of HL-60 cells.
Topics: Actins; Biopolymers; Cell Compartmentation; Cell Differentiation; Chemotaxis, Leukocyte; Contractile Proteins; Cytoskeleton; Dimethyl Sulfoxide; Filamins; Gelsolin; Humans; Leukemia, Promyelocytic, Acute; Microfilament Proteins; N-Formylmethionine Leucyl-Phenylalanine; Neoplasm Proteins; Octoxynol; Respiratory Burst; Solubility; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Topoisomerase II alpha promoter trans-activation early in monocytic differentiation of HL-60 human leukemia cells.
Topics: Base Sequence; Butyrates; Butyric Acid; Cell Differentiation; DNA Topoisomerases, Type II; Genes, Reporter; Humans; Leukemia, Promyelocytic, Acute; Molecular Sequence Data; Monocytes; Promoter Regions, Genetic; Tetradecanoylphorbol Acetate; Thymidine; Transcriptional Activation; Transfection; Tumor Cells, Cultured | 1995 |
Effects of okadaic acid and vanadate on TPA-induced monocytic differentiation in human promyelocytic leukemia cell line HL-60.
Topics: Cell Differentiation; Ethers, Cyclic; Granulocytes; Hematopoietic Stem Cells; Humans; Leukemia, Promyelocytic, Acute; Monocytes; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatases; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vanadates | 1995 |
Human promyelocytic leukemia cells (HL-60): a new model to study the effects of chemopreventive agents on H2O2 production.
Topics: Adult; Antineoplastic Agents; Dimethyl Sulfoxide; Female; Humans; Hydrogen Peroxide; Leukemia, Promyelocytic, Acute; Leukocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
DMSO, sodium butyrate, and TPA induce hypophosphorylation of RB with HL-60 cell differentiation.
Topics: Blotting, Western; Butyrates; Butyric Acid; Cell Differentiation; Dimethyl Sulfoxide; Humans; Leukemia, Promyelocytic, Acute; Phosphorylation; Retinoblastoma Protein; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
HL 60 leukaemia cells chemically induced to differentiate retain some surface glycan features of undifferentiated cells not found in normal leukocytes.
Topics: Carbohydrate Conformation; Carbohydrate Sequence; Cell Differentiation; Cell Line; Chromatography, Affinity; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Glycopeptides; Granulocytes; Humans; Leukemia, Promyelocytic, Acute; Leukocytes; Macrophages; Membrane Glycoproteins; Molecular Sequence Data; Oligosaccharides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Effects of protein kinase modulators on transferrin receptor expression in human leukaemic HL-60 cells.
Topics: Alkaloids; Bucladesine; Cell Division; Cell Line; Cyclic AMP-Dependent Protein Kinases; DNA, Neoplasm; Enzyme Activation; Gene Expression; Humans; Indoles; Isoquinolines; Leukemia, Promyelocytic, Acute; Maleimides; Protein Kinase C; Protein Kinases; Receptors, Transferrin; RNA, Messenger; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Thymidine; Tumor Cells, Cultured | 1995 |
HL-60 cell differentiation and osteopontin expression.
Topics: Cell Adhesion; Cell Differentiation; Gene Expression Regulation, Neoplastic; Humans; In Vitro Techniques; Leukemia, Promyelocytic, Acute; Osteopontin; RNA, Messenger; Sialoglycoproteins; Tetradecanoylphorbol Acetate; Tretinoin | 1995 |
Dissociation of mitogen-activated protein kinase activation from the oxidative burst in differentiated HL-60 cells and human neutrophils.
Topics: Calcium-Calmodulin-Dependent Protein Kinases; Cyclic AMP; Enzyme Activation; Humans; Leukemia, Promyelocytic, Acute; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Respiratory Burst; Superoxides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Regulation of apoptosis induced by the retinoid N-(4-hydroxyphenyl) retinamide and effect of deregulated bcl-2.
Topics: Anticarcinogenic Agents; Antimetabolites; Antioxidants; Apoptosis; Cell Differentiation; DNA, Neoplasm; Enzyme Activation; Fenretinide; Gene Expression Regulation, Leukemic; Genes, myc; Genes, p53; Glucuronates; Humans; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Promyelocytic, Acute; Lymphoma, B-Cell; Lymphoma, Follicular; Neoplasm Proteins; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Protein Kinase C; Protein Synthesis Inhibitors; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 1995 |
Activation of interleukin-1 beta gene expression during retinoic acid-induced granulocytic differentiation of promyeloid leukemia cells.
Topics: Base Sequence; Cell Differentiation; Gene Expression Regulation, Neoplastic; Granulocytes; Humans; Interleukin-1; Leukemia, Promyelocytic, Acute; Molecular Sequence Data; Monocytes; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tretinoin; Tumor Cells, Cultured | 1994 |
Induction of apoptosis by sphingosine in human leukemic HL-60 cells: a possible endogenous modulator of apoptotic DNA fragmentation occurring during phorbol ester-induced differentiation.
Topics: Apoptosis; Cell Differentiation; Cell Line; Ceramides; DNA Damage; DNA, Neoplasm; Flow Cytometry; Gene Expression; Genes, myc; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Phospholipids; Proto-Oncogene Proteins c-myc; RNA, Messenger; Sphingosine; Tetradecanoylphorbol Acetate; Time Factors; Tritium; Tumor Cells, Cultured | 1995 |
Enhanced expression of alpha v integrin subunit and osteopontin during differentiation of HL-60 cells along the monocytic pathway.
Topics: Antigens, Surface; Cell Adhesion; Cell Differentiation; Humans; Integrin alphaV; Integrins; Leukemia, Promyelocytic, Acute; Monocytes; Osteoclasts; Osteopontin; RNA, Messenger; Sialoglycoproteins; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
The arachidonate-activable, NADPH oxidase-associated H+ channel. Evidence that gp91-phox functions as an essential part of the channel.
Topics: Animals; Arachidonic Acid; B-Lymphocytes; Base Sequence; Cell Differentiation; Cell Line; Cell Line, Transformed; CHO Cells; Cricetinae; DNA, Complementary; Herpesvirus 4, Human; Humans; Hydrogen-Ion Concentration; Hygromycin B; Kinetics; Leukemia, Promyelocytic, Acute; Membrane Glycoproteins; Membrane Transport Proteins; Models, Biological; Molecular Sequence Data; NADH, NADPH Oxidoreductases; NADPH Dehydrogenase; NADPH Oxidase 2; NADPH Oxidases; Neutrophils; Phosphoproteins; Plasmids; Proton Pumps; Recombinant Proteins; Restriction Mapping; Superoxides; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1995 |
Intracellular alkalinization suppresses lovastatin-induced apoptosis in HL-60 cells through the inactivation of a pH-dependent endonuclease.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Apoptosis; Cell Cycle; Cell Line; Cycloheximide; DNA, Neoplasm; Endodeoxyribonucleases; Fluoresceins; Fluorescent Dyes; Humans; Hydrogen-Ion Concentration; Isoquinolines; Kinetics; Leukemia, Promyelocytic, Acute; Lovastatin; Mevalonic Acid; Piperazines; Protein Kinase C; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured | 1995 |
Modulation of gene expression in the acute promyelocytic leukemia cell line NB4.
Topics: Antigens, CD; Bryostatins; CD11 Antigens; Cell Differentiation; Cell Division; Cholecalciferol; Down-Regulation; Gene Expression Regulation, Leukemic; Genes, myc; Humans; Lactones; Leukemia, Promyelocytic, Acute; Macrolides; Peroxidase; RNA, Messenger; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1993 |
Dexamethasone modifies the functional responses of the granulocytic differentiating HL-60 cells.
Topics: Antigens, CD; Antigens, Differentiation, B-Lymphocyte; CD11 Antigens; Cell Differentiation; Cell Division; Cell Line; Dexamethasone; Dimethyl Sulfoxide; Gene Expression; Granulocytes; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Phospholipase D; Phospholipases A; Phospholipases A2; Receptors, Transferrin; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured; Type C Phospholipases | 1994 |
M-CSF and 1,25 dihydroxy vitamin D3 synergize with 12-O-tetradecanoylphorbol-13-acetate to induce macrophage differentiation in acute promyelocytic leukemia NB4 cells.
Topics: Calcitriol; Cell Adhesion; Cell Differentiation; Cell Division; Cell Survival; Drug Synergism; Esterases; Humans; Leukemia, Promyelocytic, Acute; Macrophage Colony-Stimulating Factor; Macrophages; Monocytes; Phagocytosis; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Synthesis of proteoglycan during HL-60 cell differentiation.
Topics: Cell Differentiation; Cell Division; Cell Line; Cholecalciferol; Chromatography, DEAE-Cellulose; Chromatography, Gel; Glucosamine; Humans; Leukemia, Promyelocytic, Acute; Proteoglycans; Sulfates; Sulfur Radioisotopes; Tetradecanoylphorbol Acetate; Tritium; Tumor Cells, Cultured | 1994 |
Mechanisms involved in the processing of the p55 and the p75 tumor necrosis factor (TNF) receptors to soluble receptor forms.
Topics: Alkaloids; Ammonium Chloride; Bucladesine; Carrier Proteins; Cyclic AMP-Dependent Protein Kinases; Down-Regulation; Endopeptidases; Enzyme-Linked Immunosorbent Assay; HeLa Cells; Humans; Leukemia, Monocytic, Acute; Leukemia, Promyelocytic, Acute; Monensin; Neoplasm Proteins; Protein Kinase C; Protein Processing, Post-Translational; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type I; Solubility; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor Decoy Receptors | 1994 |
Regulation of the human cellular glutathione peroxidase gene during in vitro myeloid and monocytic differentiation.
Topics: Cell Differentiation; Dimethylformamide; Enzyme Induction; Gene Expression Regulation, Neoplastic; Glutathione Peroxidase; Granulocytes; Humans; Leukemia, Myeloid; Leukemia, Promyelocytic, Acute; Membrane Glycoproteins; Monocytes; NADPH Oxidase 2; NADPH Oxidases; Neoplasm Proteins; Phagocytes; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Establishment of a human system that generates O2- and induces 8-hydroxydeoxyguanosine, typical of oxidative DNA damage, by a tumor promotor.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Cell Differentiation; Deoxyguanosine; Dimethyl Sulfoxide; Humans; Hydrogen Peroxide; Leukemia, Promyelocytic, Acute; Reactive Oxygen Species; Superoxides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Screening of potential chemopreventive agents using biochemical markers of carcinogenesis.
Topics: Animals; Antineoplastic Agents; Benzo(a)pyrene; Biological Assay; DNA Adducts; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Epithelium; Fibroblasts; Free Radicals; Glutathione; Humans; Leukemia, Promyelocytic, Acute; Liver; Ornithine Decarboxylase Inhibitors; Poly(ADP-ribose) Polymerase Inhibitors; Protein-Tyrosine Kinases; Rats; Rats, Inbred BUF; Tetradecanoylphorbol Acetate; Thiophenes; Trachea; Tumor Cells, Cultured | 1994 |
HL-60 cell differentiation induced by phorbol- and 12-deoxyphorbol-esters.
Topics: Cell Differentiation; Humans; Leukemia, Promyelocytic, Acute; Phorbol Esters; Protein Kinase C; Tetradecanoylphorbol Acetate; Thymidine; Tumor Cells, Cultured | 1994 |
Lineage-specific regulation of cell cycle gene expression in differentiating myeloid cells.
Topics: Base Sequence; CDC2-CDC28 Kinases; Cell Cycle; Cell Differentiation; Cell Line; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinases; Cyclins; Dimethyl Sulfoxide; DNA Primers; Gene Expression; Granulocytes; Humans; Leukemia, Promyelocytic, Acute; Macrophages; Molecular Sequence Data; Polymerase Chain Reaction; Protein Serine-Threonine Kinases; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1994 |
Inhibition of apoptosis as a mechanism of tumor promotion.
Topics: Animals; Apoptosis; Carcinogens; DDT; Diethylstilbestrol; Leukemia P388; Leukemia, Promyelocytic, Acute; Lymphoma, Large B-Cell, Diffuse; Mice; Neoplasms; Saccharin; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Ultraviolet Rays | 1994 |
Activation of protein kinase C down-regulates leukotriene C4 synthase activity and attenuates cysteinyl leukotriene production in an eosinophilic substrain of HL-60 cells.
Topics: Alkaloids; Calcimycin; Cysteine; Down-Regulation; Eosinophils; Glutathione Transferase; Humans; Leukemia, Promyelocytic, Acute; Leukotrienes; Nitriles; Phenols; Prostaglandins; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrphostins | 1994 |
Regulation of phospholipase A2 in human leukemia cell lines: its implication for intracellular signaling.
Topics: Calcium; Cell Line; Cell Membrane Permeability; Diglycerides; Electroporation; Fatty Acids, Nonesterified; Genistein; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Homeostasis; Humans; Hydrogen-Ion Concentration; Isoflavones; Kinetics; Leukemia, Promyelocytic, Acute; Lymphoma, Large B-Cell, Diffuse; Phospholipases A; Phospholipases A2; Protein-Tyrosine Kinases; Signal Transduction; Sodium Fluoride; Tetradecanoylphorbol Acetate; Thionucleotides; Tumor Cells, Cultured; Vanadates | 1994 |
Expression of a calcium binding protein pEL98 (mts1) during differentiation of human promyelocytic leukemia HL-60 cells.
Topics: Blotting, Northern; Calcium-Binding Proteins; Cell Adhesion; Cell Differentiation; Cell Movement; Dimethyl Sulfoxide; Gene Expression; Granulocytes; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Leukocytes, Mononuclear; Macrophages; Neutrophils; Phagocytosis; RNA, Messenger; S100 Calcium-Binding Protein A4; S100 Proteins; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1994 |
Characterization of the human neutrophil C1q receptor and functional effects of free ligand on activated neutrophils.
Topics: Antibodies; Blotting, Western; Carrier Proteins; Cell Differentiation; Cell Membrane; Complement C1q; Humans; Hyaluronan Receptors; In Vitro Techniques; Kinetics; Leukemia, Promyelocytic, Acute; Macrophage-1 Antigen; Membrane Glycoproteins; Mitochondrial Proteins; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Receptors, Complement; Superoxides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Up-Regulation | 1994 |
Hsp70RY: further characterization of a novel member of the hsp70 protein family.
Topics: Animals; B-Lymphocytes; Blotting, Northern; Blotting, Southern; Cell Differentiation; Cell Line; Cell Line, Transformed; Gene Expression; Genetic Variation; Glutamates; Heat-Shock Proteins; HSP110 Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Humans; Leukemia, Promyelocytic, Acute; Mice; RNA, Messenger; Sequence Homology, Amino Acid; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Potential role of phospholipase A2 in HL-60 cell differentiation to macrophages induced by protein kinase C activation.
Topics: Antigens, CD; CD11 Antigens; Cell Differentiation; Cell Line; Enzyme Activation; Fatty Acids, Nonesterified; Kinetics; Leukemia, Promyelocytic, Acute; Linoleic Acid; Linoleic Acids; Lysophosphatidylcholines; Lysophospholipids; Macrophages; Phospholipases A; Phospholipases A2; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Antisense oligonucleotides to the p65 subunit of NF-kappa B block CD11b expression and alter adhesion properties of differentiated HL-60 granulocytes.
Topics: Antigens, CD; Base Sequence; CD11 Antigens; Cell Adhesion; Cell Differentiation; Dimethyl Sulfoxide; Granulocytes; Humans; Leukemia, Promyelocytic, Acute; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; NF-kappa B; Oligonucleotides, Antisense; Phosphates; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
1,25-Dihydroxyvitamin D3 and phorbol myristate acetate synergistically increase carbonic anhydrase-II expression in a human myelomonocytic cell line.
Topics: Alkaloids; Calcitriol; Carbonic Anhydrases; Drug Synergism; Gene Expression Regulation, Enzymologic; Humans; Leukemia, Promyelocytic, Acute; Protein Kinase C; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Dissociation of endogenous cellular ceramide from NF-kappa B activation.
Topics: Antineoplastic Agents; Cell Line; Ceramides; Chloramphenicol O-Acetyltransferase; Genetic Vectors; HIV; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Leukemia, T-Cell; Morpholines; NF-kappa B; Tetradecanoylphorbol Acetate; Time Factors; Transfection; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1994 |
Enhancement of phorbol ester-induced production of tumor necrosis factor alpha by thalidomide.
Topics: Cell Line; Drug Synergism; Humans; Kinetics; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Promyelocytic, Acute; Lymphoma, Large B-Cell, Diffuse; Tetradecanoylphorbol Acetate; Thalidomide; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1994 |
Downregulation of Wilms' tumor gene (wt1) during myelomonocytic differentiation in HL60 cells.
Topics: Base Sequence; Cell Differentiation; Cholecalciferol; Dimethyl Sulfoxide; DNA-Binding Proteins; Down-Regulation; Genes, Retinoblastoma; Genes, Wilms Tumor; Humans; Leukemia, Promyelocytic, Acute; Molecular Sequence Data; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tretinoin; Tumor Cells, Cultured; WT1 Proteins | 1994 |
Bcl2 inhibits apoptosis associated with terminal differentiation of HL-60 myeloid leukemia cells.
Topics: Apoptosis; Cell Differentiation; Humans; Leukemia, Promyelocytic, Acute; Macrophages; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Tetradecanoylphorbol Acetate; Tretinoin | 1994 |
Molecular analysis of a potentially phorbol-regulatable region of the human topoisomerase II alpha gene promoter.
Topics: Base Sequence; Binding Sites; Cell Differentiation; Cell Line; Cloning, Molecular; DNA Primers; DNA Topoisomerases, Type II; Female; Gene Expression Regulation, Enzymologic; Humans; Leukemia, Promyelocytic, Acute; Lymphocytes; Molecular Sequence Data; Placenta; Polymerase Chain Reaction; Pregnancy; Promoter Regions, Genetic; Restriction Mapping; RNA, Messenger; Sequence Homology, Nucleic Acid; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Studies on the induction of lipocortin-1 by glucocorticoids.
Topics: Annexin A1; Bronchoalveolar Lavage Fluid; Cell Differentiation; Dexamethasone; Eicosanoids; Glucocorticoids; Humans; Leukemia, Promyelocytic, Acute; Macrophages, Alveolar; Methylprednisolone; Monocytes; Pneumonia; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Apoptosis of human leukemic HL-60 cells induced to differentiate by phorbol ester treatment.
Topics: Apoptosis; Cell Adhesion; Cell Differentiation; DNA Damage; DNA, Neoplasm; Granulocytes; Humans; Leukemia, Promyelocytic, Acute; Macrophages; Microscopy, Electron; Monocytes; Nucleosomes; Phagocytosis; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1994 |
Regulation of 92-kD gelatinase release in HL-60 leukemia cells: tumor necrosis factor-alpha as an autocrine stimulus for basal- and phorbol ester-induced secretion.
Topics: Alkaloids; Dexamethasone; Ditiocarb; Gelatinases; Humans; Leukemia, Promyelocytic, Acute; Molecular Weight; Pentoxifylline; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1994 |
Independent transcriptional and posttranscriptional regulation of the two tumor necrosis factor receptors in promyelocytic HL-60 cells.
Topics: Base Sequence; Bucladesine; Cell Membrane; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; DNA Primers; Enzyme Activation; Gene Expression Regulation, Neoplastic; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Molecular Sequence Data; Oligonucleotides, Antisense; Polymerase Chain Reaction; Protein Kinase C; Receptors, Tumor Necrosis Factor; RNA Processing, Post-Transcriptional; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Transcription, Genetic; Tumor Cells, Cultured | 1993 |
Tumor necrosis factor-dependent production of human immunodeficiency virus 1 in chronically infected HL-60 cells.
Topics: Calcitriol; HIV-1; Humans; Leukemia, Promyelocytic, Acute; Receptors, Tumor Necrosis Factor; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Virus Activation; Zidovudine | 1993 |
Differentiation of HL60 promyelocytic cells is promoted by a 'differentiation enhancing factor' produced by erythroleukemia cells.
Topics: Cell Differentiation; Cell Line; HMGB1 Protein; Humans; Isoenzymes; Kinetics; Leukemia, Erythroblastic, Acute; Leukemia, Promyelocytic, Acute; Neoplasm Proteins; Organothiophosphates; Protein Kinase C; Tetradecanoylphorbol Acetate; Time Factors; Tretinoin; Tumor Cells, Cultured | 1993 |
Induction of granulocytic maturation in HL-60 human leukemia cells by free radicals: a hypothesis of cell differentiation involving hydroxyl radicals.
Topics: Cell Differentiation; Cell Division; Cell Line; Dimethyl Sulfoxide; DNA Replication; Flow Cytometry; Free Radicals; Granulocytes; Humans; Hydrogen Peroxide; Hydroxyl Radical; Iron; Kinetics; Leukemia, Promyelocytic, Acute; Models, Biological; Tetradecanoylphorbol Acetate; Thymidine; Time Factors; Tumor Cells, Cultured | 1993 |
Expression and modulation of annexin VIII in human leukemia-lymphoma cell lines.
Topics: Annexins; Blotting, Northern; Bryostatins; Cell Differentiation; Cholecalciferol; Dactinomycin; Gene Expression Regulation, Neoplastic; Half-Life; Humans; Lactones; Leukemia; Leukemia, Myeloid; Leukemia, Promyelocytic, Acute; Lymphoma; Macrolides; RNA, Messenger; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1993 |
Phorbol ester induces apoptosis in HL-60 promyelocytic leukemia cells but not in HL-60 PET mutant.
Topics: Apoptosis; Calcimycin; DNA Damage; DNA, Neoplasm; Drug Tolerance; Etoposide; Humans; Leukemia, Promyelocytic, Acute; Mutation; Novobiocin; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Changes in the susceptibility of 12-O-tetradecanoylphorbol 13-acetate (TPA)-treated HL-60 cells to staphylococcal leukocidin.
Topics: Calcium Chloride; Dose-Response Relationship, Drug; Humans; Leukemia, Promyelocytic, Acute; Leukocidins; Phospholipases A; Phospholipases A2; Staphylococcus; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Phosphorylation of a 72-kDa nucleoprotein (NP-72) in HL-60 cells is mediated by the double-stranded DNA-dependent protein kinase (DNA-PK).
Topics: Antibodies, Monoclonal; Blotting, Western; Cell Differentiation; Cell Nucleus; DNA-Activated Protein Kinase; DNA-Binding Proteins; Down-Regulation; Electrophoresis, Gel, Two-Dimensional; Humans; Leukemia, Promyelocytic, Acute; Molecular Weight; Nuclear Proteins; Nucleoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
All-trans retinoic acid reverses phorbol ester resistance in a human myeloid leukemia cell line.
Topics: Cell Differentiation; Cell Division; Drug Resistance; Gene Expression Regulation, Enzymologic; Humans; Leukemia, Promyelocytic, Acute; Protein Kinase C; Receptor, Macrophage Colony-Stimulating Factor; RNA, Messenger; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1994 |
gCap39 is a nuclear and cytoplasmic protein.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Cell Differentiation; Cell Nucleus; Cytoplasm; Fluorescent Antibody Technique; Gene Expression Regulation, Leukemic; Leukemia, Promyelocytic, Acute; Macrophages, Peritoneal; Mice; Mice, Inbred C3H; Microfilament Proteins; Molecular Sequence Data; Neoplasm Proteins; Nuclear Proteins; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Regulation of phospholipase A2 activity in undifferentiated and neutrophil-like HL60 cells. Linkage between impaired responses to agonists and absence of protein kinase C-dependent phosphorylation of cytosolic phospholipase A2.
Topics: Adenosine Triphosphate; Aluminum Compounds; Arachidonic Acid; Blotting, Western; Bucladesine; Calcimycin; Calcium; Cell Differentiation; Cell Line; Cytosol; Electrophoresis, Polyacrylamide Gel; Fluorides; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Kinetics; Leukemia, Promyelocytic, Acute; Neutrophils; Phospholipases A; Phospholipases A2; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Involvement of CD4 in interleukin-6 secretion by U937 monocytic cells stimulated with the lectin jacalin.
Topics: Antibodies, Monoclonal; Antigens, CD; Biological Assay; Calcitriol; CD4 Antigens; Cell Differentiation; Cell Line; Flow Cytometry; HIV Envelope Protein gp120; Humans; Interferon Inducers; Interleukin-1; Interleukin-6; Lectins; Leukemia, Promyelocytic, Acute; Lipopolysaccharides; Luminescent Measurements; Monocytes; Plant Lectins; Recombinant Proteins; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1994 |
Changes in proteoglycan core protein (PCP) mRNA levels during HL-60 cell differentiation.
Topics: Aggrecans; Alkaloids; Blotting, Northern; Cell Differentiation; Dimethyl Sulfoxide; Extracellular Matrix Proteins; Gene Expression; Genes, myc; Glycoproteins; Granulocytes; Humans; Kinetics; Lectins, C-Type; Leukemia, Promyelocytic, Acute; Neoplasm Proteins; Protein Kinase C; Proteoglycans; RNA, Messenger; RNA, Ribosomal, 18S; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Glucocorticoid receptor expression during differentiation of human promyeloic leukemia cells.
Topics: Cell Differentiation; Dimethyl Sulfoxide; Glucocorticoids; Humans; Leukemia, Promyelocytic, Acute; Receptors, Glucocorticoid; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Prothymosin alpha gene expression correlates with proliferation, not differentiation, of HL-60 cells.
Topics: Cell Differentiation; Cell Division; Dimethyl Sulfoxide; Gene Expression Regulation, Leukemic; Genes, myc; Humans; Interferon-gamma; Leukemia, Promyelocytic, Acute; Protein Precursors; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Thymosin; Tumor Cells, Cultured | 1993 |
Heat shock protein is a unique marker of growth arrest during macrophage differentiation of HL-60 cells.
Topics: Biomarkers; Cell Differentiation; Cell Division; Heat-Shock Proteins; Homeostasis; Humans; Leukemia, Promyelocytic, Acute; Macrophages; Molecular Weight; Phosphorylation; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Butyric acid and its monosaccharide ester induce apoptosis in the HL-60 cell line.
Topics: Antineoplastic Agents; Apoptosis; Butyrates; Butyric Acid; Cell Line; Cell Survival; DNA, Neoplasm; Glucose; Humans; Leukemia, Promyelocytic, Acute; Monosaccharides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Differential induction of apoptosis in undifferentiated and differentiated HL-60 cells by DNA topoisomerase I and II inhibitors.
Topics: Amsacrine; Apoptosis; Camptothecin; Cell Differentiation; DNA; DNA Damage; Etoposide; Humans; Leukemia, Promyelocytic, Acute; Tetradecanoylphorbol Acetate; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tretinoin; Tumor Cells, Cultured | 1993 |
Reactive oxygen intermediates target CC(A/T)6GG sequences to mediate activation of the early growth response 1 transcription factor gene by ionizing radiation.
Topics: Actins; Animals; Base Sequence; Cell Nucleus; Chickens; Chloramphenicol O-Acetyltransferase; Clone Cells; DNA-Binding Proteins; Early Growth Response Protein 1; Gene Expression Regulation, Neoplastic; Globins; Humans; Hydrogen Peroxide; Immediate-Early Proteins; Leukemia, Promyelocytic, Acute; Molecular Sequence Data; Oligodeoxyribonucleotides; Promoter Regions, Genetic; Recombinant Fusion Proteins; Simplexvirus; Tetradecanoylphorbol Acetate; Thymidine Kinase; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured; X-Rays | 1993 |
Phosphorylation of human topoisomerase I by protein kinase C in vitro and in phorbol 12-myristate 13-acetate-activated HL-60 promyelocytic leukaemia cells.
Topics: Animals; Brain; DNA Topoisomerases, Type I; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Peptide Mapping; Phosphorylation; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Trypsin; Tumor Cells, Cultured | 1993 |
Down-regulation by retinoic acid of the catalytic subunit of protein phosphatase type 2A during granulocytic differentiation of HL-60 cells.
Topics: Cell Differentiation; Cytosol; Electrophoresis, Agar Gel; Electrophoresis, Polyacrylamide Gel; Granulocytes; Humans; Isoenzymes; Kinetics; Leukemia, Promyelocytic, Acute; Macromolecular Substances; Molecular Weight; Phosphoprotein Phosphatases; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Time Factors; Tretinoin; Tumor Cells, Cultured | 1993 |
Phosphorylation of Na(+)-H+ antiporter is not stimulated by phorbol ester and acidification in granulocytic HL-60 cells.
Topics: Carrier Proteins; Cell Differentiation; Humans; Hydrogen-Ion Concentration; Kinetics; Leukemia, Promyelocytic, Acute; Phosphoproteins; Phosphorylation; RNA, Messenger; Sodium; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1993 |
Induction of functional lipoxin A4 receptors in HL-60 cells.
Topics: Binding, Competitive; Dactinomycin; Dimethyl Sulfoxide; Enzyme Activation; Humans; Hydroxyeicosatetraenoic Acids; Leukemia, Promyelocytic, Acute; Leukotriene B4; Lipoxins; Neutrophils; Receptors, Cell Surface; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured; Type C Phospholipases | 1993 |
Defective translocation of protein kinase C in multidrug-resistant HL-60 cells confers a reversible loss of phorbol ester-induced monocytic differentiation.
Topics: Calcium-Calmodulin-Dependent Protein Kinases; Cell Adhesion; Cell Differentiation; Cell Nucleus; Drug Resistance; Ethers, Cyclic; Gene Expression; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Monocytes; Okadaic Acid; Phosphoprotein Phosphatases; Protein Kinase C; Protein Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Proto-Oncogenes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vincristine | 1993 |
Regulation of release of hepatocyte growth factor from human promyelocytic leukemia cells, HL-60, by 1,25-dihydroxyvitamin D3, 12-O-tetradecanoylphorbol 13-acetate, and dibutyryl cyclic adenosine monophosphate.
Topics: Alkaline Phosphatase; Animals; Bone Marrow Cells; Bucladesine; Calcitriol; Cell Division; Gene Expression; Hepatocyte Growth Factor; In Vitro Techniques; Leukemia, Promyelocytic, Acute; Mice; Osteoblasts; Protein Kinase C; RNA, Messenger; Secretory Rate; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Spin trapping of superoxide released by opsonized asbestos from human promyelocytic leukemia cell line, HL60.
Topics: Asbestos; Asbestos, Crocidolite; Cell Differentiation; Cyclic N-Oxides; Deferoxamine; Dimethyl Sulfoxide; Electron Spin Resonance Spectroscopy; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Pentetic Acid; Spin Labels; Superoxides; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured | 1993 |
Novel fluoride-stimulated dichlorofluorescin dye oxidation pathway in human leukemia cell lines.
Topics: Cell Cycle; Cell Differentiation; Dimethylformamide; Flow Cytometry; Fluoresceins; Humans; Hydrogen Peroxide; Kinetics; Leukemia, Myeloid; Leukemia, Promyelocytic, Acute; Oxidation-Reduction; Sodium Fluoride; Superoxides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Evidence against a requirement for Na+/H+ exchange activity for proliferation or differentiation of HL60 leukemic cells.
Topics: Amiloride; Bicarbonates; Calcitriol; Carrier Proteins; Cell Adhesion; Cell Differentiation; Cell Division; Dimethyl Sulfoxide; Hydrogen-Ion Concentration; Interferon-gamma; Leukemia, Promyelocytic, Acute; Neoplasm Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-myc; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tretinoin; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1993 |
Regulation of the expression of galactoside-binding lectin during human monocytic differentiation.
Topics: Actins; Blotting, Northern; Blotting, Western; Cell Differentiation; Cell Nucleus; Dactinomycin; Fluorescent Antibody Technique; Galactosides; Galectins; Gene Expression; Hemagglutinins; Humans; Leukemia, Promyelocytic, Acute; Monocytes; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tretinoin; Tumor Cells, Cultured | 1993 |
A quantitative ultrastructural and cytochemical study of TPA-induced differentiation in HL-60 cells.
Topics: Cell Differentiation; Histocytochemistry; Humans; Lectins; Leukemia, Promyelocytic, Acute; Membrane Glycoproteins; Microscopy, Electron; Monocytes; Organelles; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
The regulation of thymidine kinase in HL-60 human promyeloleukemia cells.
Topics: Amino Acids; Blotting, Northern; Cell Differentiation; Cell Division; Cycloheximide; Cytosol; Dactinomycin; Enzyme Stability; Homeostasis; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Mitosis; Molecular Weight; Phosphopeptides; Phosphorylation; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Thymidine Kinase; Tumor Cells, Cultured | 1993 |
Human immunodeficiency virus-1 infection of the human promyelocytic cell line HL-60: high frequency of low-level infection and effect of subsequent cell differentiation.
Topics: Antigens, CD; Base Sequence; Cell Differentiation; Chloramphenicol O-Acetyltransferase; Clone Cells; Dimethyl Sulfoxide; HIV Long Terminal Repeat; HIV-1; Humans; Leukemia, Promyelocytic, Acute; Molecular Sequence Data; NF-kappa B; Oligodeoxyribonucleotides; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured; Virus Replication | 1993 |
1,25-Dihydroxyvitamin D3 and phorbol myristate acetate produce divergent phenotypes in a monomyelocytic cell line.
Topics: Base Sequence; Calcitriol; Carbonic Anhydrases; Cell Differentiation; DNA Probes; Dose-Response Relationship, Drug; Genes, fms; Humans; Isoenzymes; Kinetics; Leukemia, Promyelocytic, Acute; Molecular Sequence Data; Monocytes; Oligonucleotide Probes; Osteoclasts; Receptor, Macrophage Colony-Stimulating Factor; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Selective eicosanoid formation during HL-60 macrophage differentiation. Regulation of thromboxane synthase.
Topics: Cell Differentiation; Eicosanoids; Humans; Leukemia, Promyelocytic, Acute; Macrophages; Tetradecanoylphorbol Acetate; Thromboxane-A Synthase; Thromboxanes; Tumor Cells, Cultured | 1993 |
Cobra venom cardiotoxin (cytotoxin) isoforms and neurotoxin: comparative potency of protein kinase C inhibition and cancer cell cytotoxicity and modes of enzyme inhibition.
Topics: Amino Acid Sequence; Animals; Brain; Cell Differentiation; Cell Survival; Cytotoxins; Elapid Venoms; Humans; Kinetics; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Promyelocytic, Acute; Molecular Sequence Data; Neurotoxins; Phorbol 12,13-Dibutyrate; Protein Kinase C; Sequence Homology, Amino Acid; Structure-Activity Relationship; Swine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Glycosphingolipid patterns in human promyelocytic HL-60 leukemia cells susceptible or resistant to differentiation induction by phorbol 12-myristate 13-acetate.
Topics: beta-D-Galactoside alpha 2-6-Sialyltransferase; Carbohydrate Sequence; Cell Differentiation; Enzyme Induction; G(M3) Ganglioside; Glycosphingolipids; Humans; Leukemia, Promyelocytic, Acute; Molecular Sequence Data; Monocytes; Sialyltransferases; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Agonist-dependent phosphorylation of N-formylpeptide and activation peptide from the fifth component of C (C5a) chemoattractant receptors in differentiated HL60 cells.
Topics: Amino Acid Sequence; beta-Adrenergic Receptor Kinases; Complement C5a; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Activation; Humans; Leukemia, Promyelocytic, Acute; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Phosphorylation; Precipitin Tests; Protein Kinase C; Protein Kinases; Receptor, Anaphylatoxin C5a; Receptors, Complement; Receptors, Formyl Peptide; Receptors, Immunologic; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
5'-adenosine monophosphate is the neutrophil-derived paracrine factor that elicits chloride secretion from T84 intestinal epithelial cell monolayers.
Topics: Adenine Nucleotides; Adenosine Monophosphate; Chlorides; Chromatography, High Pressure Liquid; Colonic Neoplasms; Culture Media, Conditioned; Epithelium; Humans; Intestines; Kinetics; Leukemia, Promyelocytic, Acute; Models, Biological; Neutrophils; Ribonucleotides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Differential expression of the chromosomal high mobility group proteins 14 and 17 during the onset of differentiation in mammalian osteoblasts and promyelocytic leukemia cells.
Topics: Animals; Cell Differentiation; Cell Division; Cells, Cultured; Extracellular Matrix; Gene Expression Regulation; High Mobility Group Proteins; Humans; Leukemia, Promyelocytic, Acute; Macrophages; Monocytes; Osteoblasts; Phenotype; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Phorbol ester stimulates the activity of a protein tyrosine phosphatase containing SH2 domains (PTP1C) in HL-60 leukemia cells by increasing gene expression.
Topics: Base Sequence; Cycloheximide; DNA, Neoplasm; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Genes, src; Humans; Immunoblotting; Isoenzymes; Kinetics; Leukemia, Promyelocytic, Acute; Molecular Sequence Data; Oligodeoxyribonucleotides; Protein Tyrosine Phosphatases; RNA, Messenger; Sequence Homology, Nucleic Acid; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Transcription, Genetic; Tumor Cells, Cultured | 1993 |
1,25-dihydroxyvitamin D3 primes acute promyelocytic cells for TPA-induced monocytic differentiation through both PKC and tyrosine phosphorylation cascades.
Topics: Alkaloids; Calcitriol; Cell Differentiation; Enzyme Inhibitors; Genistein; Humans; Indoles; Isoflavones; Leukemia, Promyelocytic, Acute; Maleimides; Monocytes; Phagocytosis; Phosphorylation; Protein Kinase C; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine; Vanadates | 1996 |
Direct measurement of oscillatory generation of superoxide anions by single phagocytes.
Topics: Anions; Humans; Immunoglobulin G; Kinetics; Leukemia, Promyelocytic, Acute; Microelectrodes; NADP; Opsonin Proteins; Phagocytes; Phagocytosis; Superoxides; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1996 |
bcl-2 protein downregulation is not required for differentiation of multidrug resistant HL60 leukemia cells.
Topics: bcl-2-Associated X Protein; Blotting, Western; Cell Differentiation; Down-Regulation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Genes, myc; Half-Life; HL-60 Cells; Humans; Leukemia, Promyelocytic, Acute; Oncogene Protein p21(ras); Polymerase Chain Reaction; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-myc; Tetradecanoylphorbol Acetate | 1996 |
Fatty acid synthase (FAS): a target for cytotoxic antimetabolites in HL60 promyelocytic leukemia cells.
Topics: Antineoplastic Agents; Blotting, Northern; Cell Differentiation; Cerulenin; Culture Media, Serum-Free; Fatty Acid Synthases; Fatty Acids, Nonesterified; Flow Cytometry; Gene Expression; HL-60 Cells; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Oleic Acid; Oleic Acids; Palmitic Acid; Palmitic Acids; RNA, Messenger; Serum Albumin, Bovine; Tetradecanoylphorbol Acetate | 1996 |
1,25-Dihydroxyvitamin D3 stimulates expression and translocation of protein kinase Calpha and Cdelta via a nongenomic mechanism and rapidly induces phosphorylation of a 33-kDa protein in acute promyelocytic NB4 cells.
Topics: Blotting, Western; Calcitriol; Cell Line; Electrophoresis, Polyacrylamide Gel; Gene Expression; Humans; Isoenzymes; Leukemia, Promyelocytic, Acute; Molecular Weight; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-delta; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1996 |
Effects of 1,25-dihydroxy vitamin D3 on all-trans retinoic acid sensitive and resistant acute promyelocytic leukemia cells.
Topics: Antigens, CD; Base Sequence; Cell Line; DNA Primers; Drug Resistance, Neoplasm; Gene Expression; HLA-DR Antigens; Humans; Integrin alphaXbeta2; Leukemia, Promyelocytic, Acute; Lipopolysaccharide Receptors; Macrophage-1 Antigen; Molecular Sequence Data; Polymerase Chain Reaction; Receptors, Retinoic Acid; Retinoid X Receptors; Tetradecanoylphorbol Acetate; Transcription Factors; Tretinoin; Tumor Cells, Cultured | 1996 |
Overexpression of poly(ADP-ribose) polymerase promotes cell cycle arrest and inhibits neutrophilic differentiation of NB4 acute promyelocytic leukemia cells.
Topics: Cell Cycle; Cell Differentiation; Cell Division; Cholecalciferol; Gene Expression; Humans; Leukemia, Promyelocytic, Acute; Neutrophils; Plasmids; Poly(ADP-ribose) Polymerases; Sensitivity and Specificity; Tetradecanoylphorbol Acetate; Transfection; Tretinoin; Tumor Cells, Cultured | 1996 |
Cloning and characterization of phorbol ester differentiation-resistant U937 cell variants.
Topics: CD18 Antigens; Cell Differentiation; Cell Division; Clone Cells; Down-Regulation; Drug Resistance; Enzyme Activation; Humans; Leukemia, Promyelocytic, Acute; NADPH Oxidases; Phosphoproteins; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1997 |
Defective microtubule reorganization in phorbol ester-resistant U937 variants: reconstitution of the normal cell phenotype with nocodazole treatment.
Topics: Antineoplastic Agents; Cell Adhesion; Clone Cells; Drug Resistance; Flow Cytometry; Humans; Leukemia, Promyelocytic, Acute; Microtubule-Associated Proteins; Microtubules; NADPH Oxidases; Nocodazole; Phenotype; Protein Binding; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1997 |
Auraptene, a citrus coumarin, inhibits 12-O-tetradecanoylphorbol-13-acetate-induced tumor promotion in ICR mouse skin, possibly through suppression of superoxide generation in leukocytes.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogens; Cell Line; Citrus; Coumarins; Female; Flow Cytometry; Fluorescent Dyes; Humans; Leukemia, Promyelocytic, Acute; Leukocytes; Mice; Mice, Inbred ICR; Skin Neoplasms; Superoxides; Tetradecanoylphorbol Acetate; Umbelliferones | 1997 |
Retinoic acid induces aggregation of the acute promyelocytic leukemia cell line NB-4 by utilization of LFA-1 and ICAM-2.
Topics: Antibodies, Monoclonal; Antigens, CD; Antineoplastic Agents; Cell Adhesion Molecules; Cell Aggregation; Cell Differentiation; Edetic Acid; Humans; Integrin alpha4beta1; Integrins; Leukemia, Promyelocytic, Acute; Lymphocyte Function-Associated Antigen-1; Methylprednisolone Hemisuccinate; Neoplasm Proteins; Neoplastic Stem Cells; Receptors, Lymphocyte Homing; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1997 |
Common defects of different retinoic acid resistant promyelocytic leukemia cells are persistent telomerase activity and nuclear body disorganization.
Topics: Antineoplastic Agents; Binding Sites; Blotting, Western; Carcinogens; Cell Differentiation; Cell Division; Cell Nucleus; Cholecalciferol; Clone Cells; DNA, Neoplasm; Drug Resistance, Neoplasm; Humans; Leukemia, Promyelocytic, Acute; Methylnitronitrosoguanidine; Polymerase Chain Reaction; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Telomerase; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tretinoin; Tumor Cells, Cultured | 1997 |
Expression of NADPH oxidase is induced by all-trans retinoic acid but not by phorbol myristate acetate and 1,25 dihydroxyvitamin D3 in the human promyelocytic cell line NB4.
Topics: Calcitriol; Humans; Leukemia, Promyelocytic, Acute; NADPH Oxidases; Superoxides; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1997 |
Cross-talk between protein kinase C-alpha (PKC-alpha) and -delta (PKC-delta): PKC-alpha elevates the PKC-delta protein level, altering its mRNA transcription and degradation.
Topics: Animals; Enzyme Activation; Enzyme Stability; Indoles; Isoenzymes; Leukemia, Promyelocytic, Acute; Lymphoma, B-Cell; Maleimides; Mice; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-delta; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured; Up-Regulation | 1998 |
Histamine synthesis by liver macrophages and its role in regeneration of the injured liver.
Topics: Animals; Carbon Tetrachloride; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Hepatocyte Growth Factor; Histamine; Histidine Decarboxylase; HL-60 Cells; Humans; Leukemia, Promyelocytic, Acute; Liver; Liver Regeneration; Macrophages; Male; Mice; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1998 |
1Alpha,25-dihydroxyvitamin D3 and phorbol ester mediate the expression of alkaline phosphatase in NB4 acute promyelocytic leukemia cells.
Topics: Alkaline Phosphatase; Calcitriol; Carcinogens; Cell Differentiation; Dose-Response Relationship, Drug; Humans; Leukemia, Promyelocytic, Acute; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1998 |
Pentoxifylline synergizes with all-trans retinoic acid to induce differentiation of HL-60 myelocytic cells, but suppresses tRA-augmented clonal growth of normal CFU-GM.
Topics: Bone Marrow Cells; CD11 Antigens; Cell Differentiation; Cell Division; Clone Cells; Cyclic AMP; Drug Synergism; Granulocytes; HL-60 Cells; Humans; Leukemia, Promyelocytic, Acute; Macrophages; Pentoxifylline; Phosphodiesterase Inhibitors; Respiratory Burst; Tetradecanoylphorbol Acetate; Tretinoin | 1998 |
Autocrine regulation of matrix metalloproteinase-9 gene expression and secretion by tumor necrosis factor-alpha (TNF-alpha) in NB4 leukemic cells: specific involvement of TNF receptor type 1.
Topics: Amino Acid Sequence; Antibodies, Monoclonal; Antibody Specificity; Antigens, CD; Collagenases; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Leukemic; Humans; Leukemia, Promyelocytic, Acute; Matrix Metalloproteinase 9; Molecular Sequence Data; Neutralization Tests; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type I; Receptors, Tumor Necrosis Factor, Type II; Tetradecanoylphorbol Acetate; Tissue Inhibitor of Metalloproteinase-1; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1998 |
Interaction between alpha 5 beta 1 integrin and secreted fibronectin is involved in macrophage differentiation of human HL-60 myeloid leukemia cells.
Topics: Cell Differentiation; Enzyme Activation; Enzyme Precursors; Fibronectins; Gene Expression Regulation, Neoplastic; HL-60 Cells; Humans; Intracellular Signaling Peptides and Proteins; Isoenzymes; Leukemia, Promyelocytic, Acute; Macrophages; Protein Kinase C; Protein Kinase C beta; Protein-Tyrosine Kinases; Receptors, Fibronectin; Syk Kinase; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1999 |
Bryostatin-1 and 1alpha,25-dihydroxyvitamin D3 synergistically stimulate the differentiation of NB4 acute promyelocytic leukemia cells.
Topics: Alkaline Phosphatase; Antineoplastic Combined Chemotherapy Protocols; Bryostatins; Calcitriol; Cell Differentiation; Cell Division; Drug Synergism; Enzyme Induction; Humans; Lactones; Leukemia, Promyelocytic, Acute; Macrolides; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1999 |
Lineage-specific modulation of calcium pump expression during myeloid differentiation.
Topics: Calcium; Calcium-Transporting ATPases; Cell Differentiation; Cyclic AMP; Drug Resistance; Endoplasmic Reticulum; Gene Expression; Granulocytes; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Macrophages; RNA, Messenger; Sarcoplasmic Reticulum; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1999 |
Induction of differentiation in U-937 and NB4 cells is associated with inhibition of tissue factor production.
Topics: Cell Cycle; Cell Differentiation; Cholecalciferol; Gene Expression Regulation, Leukemic; Humans; Interferon-alpha; Interferon-gamma; Interleukin-1; Ionomycin; Leukemia, Promyelocytic, Acute; Lipopolysaccharides; Neoplasm Proteins; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Thromboplastin; Tretinoin; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; U937 Cells | 1999 |
Expression of cancer-related genes in human cells exposed to 60 Hz magnetic fields.
Topics: Breast; Cell Line; Cell Line, Transformed; Down-Regulation; Electromagnetic Fields; Epithelial Cells; Female; Gene Expression; Gene Expression Profiling; Gene Expression Regulation, Leukemic; HL-60 Cells; Humans; Leukemia, Promyelocytic, Acute; Oncogenes; Reproducibility of Results; Tetradecanoylphorbol Acetate; Up-Regulation | 2000 |
Functional characterization of the two alternative promoters of human p45 NF-E2 gene.
Topics: Binding Sites; Blotting, Northern; Cell Differentiation; Cell Line; Cells, Cultured; DNA-Binding Proteins; Erythrocytes; Erythroid-Specific DNA-Binding Factors; Fetal Blood; Humans; Leukemia, Promyelocytic, Acute; Megakaryocytes; NF-E2 Transcription Factor; NF-E2 Transcription Factor, p45 Subunit; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription Factors; Transfection; Tumor Cells, Cultured | 2000 |
1alpha,25-dihydroxyvitamin D3 stimulates phosphorylation of IkappaBalpha and synergizes with TPA to induce nuclear translocation of NFkappaB during monocytic differentiation of NB4 leukemia cells.
Topics: Active Transport, Cell Nucleus; Calcitriol; Calcium Signaling; Calpain; Cell Differentiation; Cell Nucleus; DNA-Binding Proteins; Drug Synergism; Humans; I-kappa B Kinase; I-kappa B Proteins; Leukemia, Promyelocytic, Acute; Monocytes; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; Protein Serine-Threonine Kinases; Receptors, Calcitriol; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors; Transcription Factor RelA; Tumor Cells, Cultured | 2002 |
Isoprenoid metabolism is required for stimulation of the respiratory burst oxidase of HL-60 cells.
Topics: Butadienes; Enzyme Activation; GTP-Binding Proteins; Hemiterpenes; Humans; Leukemia, Promyelocytic, Acute; Lovastatin; Mevalonic Acid; NADH, NADPH Oxidoreductases; NADPH Oxidases; Pentanes; Respiratory Burst; Superoxides; Terpenes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
Selective decrease in cell surface expression and mRNA level of the 55-kDa tumor necrosis factor receptor during differentiation of HL-60 cells into macrophage-like but not granulocyte-like cells.
Topics: Cell Differentiation; Cell Membrane; Gene Expression; Granulocytes; In Vitro Techniques; Leukemia, Promyelocytic, Acute; Macrophages; Molecular Weight; Receptors, Cell Surface; Receptors, Tumor Necrosis Factor; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1992 |
[Effect of cyclic AMP and phorbol ester on PAI-2 synthesis in a leukemic cell line PL-21 and on u-PA secretion in a pre-B cell lymphoma cell line RC-K8].
Topics: Cyclic AMP; Dexamethasone; Humans; Leukemia, Promyelocytic, Acute; Lymphoma, B-Cell; Plasminogen Inactivators; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Urokinase-Type Plasminogen Activator | 1992 |
A switch toward demethylation is associated with the expression of myeloperoxidase in acute myeloblastic and promyelocytic leukemias.
Topics: Blotting, Northern; Blotting, Southern; DNA Probes; DNA, Neoplasm; Gene Expression; Humans; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Methylation; Peroxidase; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
Dephosphorylation of the retinoblastoma protein during differentiation of HL60 cells.
Topics: Bucladesine; Cell Differentiation; Cyclic AMP; Humans; Immunosorbent Techniques; Leukemia, Promyelocytic, Acute; Macrophages; Phosphorylation; Protein Kinase C; Retinoblastoma Protein; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
Synergistic action of tiazofurin and difluorodeoxycytidine on differentiation and cytotoxicity.
Topics: Animals; Antimetabolites, Antineoplastic; Cell Differentiation; Cell Line; Cell Survival; Deoxycytidine; Dose-Response Relationship, Drug; Drug Synergism; Female; Gemcitabine; Humans; IMP Dehydrogenase; Kinetics; Leukemia, Promyelocytic, Acute; Liver Neoplasms, Experimental; Models, Biological; Ovarian Neoplasms; Pancreatic Neoplasms; Rats; Ribavirin; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Stem Cell Assay | 1992 |
Cloning and analysis of the CD18 promoter.
Topics: Antigens, CD; Base Sequence; CD18 Antigens; Cell Line; Cell Nucleus; Cloning, Molecular; DNA Probes; Genomic Library; Humans; Leukemia, Promyelocytic, Acute; Molecular Sequence Data; Oligodeoxyribonucleotides; Promoter Regions, Genetic; Protein Biosynthesis; Receptors, Leukocyte-Adhesion; Restriction Mapping; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection | 1992 |
Hsp60/chaperonin gene expression and differentiation of human colon adenocarcinoma and multipotent leukaemic cells.
Topics: Adenocarcinoma; Cell Differentiation; Chaperonins; Colonic Neoplasms; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; Gene Library; Glucose; Heat-Shock Proteins; Humans; Leukemia, Promyelocytic, Acute; Mitochondria; Molecular Sequence Data; Proteins; Restriction Mapping; RNA, Neoplasm; Tetradecanoylphorbol Acetate | 1992 |
The insulin-like growth factor 1 receptor is required for the proliferation of hemopoietic cells.
Topics: Base Sequence; Cell Division; DNA; Humans; Leukemia, Promyelocytic, Acute; Leukocytes, Mononuclear; Molecular Sequence Data; Nuclear Proteins; Oligonucleotides, Antisense; Oncogenes; Proliferating Cell Nuclear Antigen; Proto-Oncogene Mas; Receptor, IGF Type 1; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
A lineage-specific Ca(2+)-activated K+ conductance in HL-60 cells.
Topics: Bucladesine; Calcium; Cell Differentiation; Charybdotoxin; Granulocytes; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Leukemia, Promyelocytic, Acute; Macrophages; Membrane Potentials; Potassium Channels; Scorpion Venoms; Tetradecanoylphorbol Acetate; Tretinoin | 1992 |
Phorbol ester-induced promyelocytic leukemia cell adhesion to marrow stromal cells involves fibronectin specific alpha 5 beta 1 integrin receptors.
Topics: Bone Marrow; Cell Adhesion; Enzyme Activation; Extracellular Matrix; Fibronectins; Humans; Integrins; Leukemia, Promyelocytic, Acute; Protein Kinase C; Radioligand Assay; Receptors, Fibronectin; Receptors, Immunologic; Receptors, Very Late Antigen; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
Modulation of protein kinase C-epsilon by phorbol esters in the monoblastoid U937 cell.
Topics: Cell Differentiation; Enzyme Activation; Enzyme Induction; Humans; Leukemia, Myeloid; Leukemia, Promyelocytic, Acute; Monocytes; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
Resistance to 1,25-dihydroxyvitamin D3 of a deoxycytidine kinase-deficient variant of human leukemia HL60 cells.
Topics: Biological Transport; Calcitriol; Cell Differentiation; Cell Division; Cell Survival; Clone Cells; Cytarabine; Deoxycytidine Kinase; Drug Resistance; Gene Expression; Genes, myc; Genetic Variation; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Monocytes; Oligonucleotide Probes; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured | 1992 |
Total metabolic flow of glycosphingolipid biosynthesis is regulated by UDP-GlcNAc:lactosylceramide beta 1-->3N-acetylglucosaminyltransferase and CMP-NeuAc:lactosylceramide alpha 2-->3 sialyltransferase in human hematopoietic cell line HL-60 during differe
Topics: Antibodies, Monoclonal; beta-Galactoside alpha-2,3-Sialyltransferase; Carbohydrate Sequence; Cell Differentiation; Gangliosides; Glycosphingolipids; Hematopoiesis; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Molecular Sequence Data; N-Acetylglucosaminyltransferases; Oligosaccharides; Sialyltransferases; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1992 |
Protein kinase C beta gene expression is associated with susceptibility of human promyelocytic leukemia cells to phorbol ester-induced differentiation.
Topics: Cell Differentiation; Drug Resistance; Enzyme Induction; Gene Expression Regulation, Leukemic; Genes, fos; Genes, jun; Humans; Isoenzymes; Leukemia, Promyelocytic, Acute; Male; Neoplasm Proteins; Protein Kinase C; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; RNA, Messenger; RNA, Neoplasm; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
Structure and expression of neutrophil gelatinase cDNA. Identity with type IV collagenase from HT1080 cells.
Topics: Base Sequence; Blotting, Northern; Cell Line; Cloning, Molecular; Collagenases; DNA; Gene Library; Humans; Leukemia, Promyelocytic, Acute; Matrix Metalloproteinase 9; Molecular Sequence Data; Neutrophils; Oligodeoxyribonucleotides; Oligonucleotides, Antisense; Polymerase Chain Reaction; Protein Biosynthesis; Restriction Mapping; RNA, Messenger; Sulfuric Acid Esters; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
Expression of 92 kDa phagocyte gelatinase by inflammatory and connective tissue cells.
Topics: Cell Differentiation; Collagenases; Connective Tissue; Enzyme Induction; Fibroblasts; Humans; Inflammation; Leukemia, Monocytic, Acute; Leukemia, Promyelocytic, Acute; Macrophages, Alveolar; Matrix Metalloproteinase 9; Molecular Weight; Monocytes; Neoplasm Proteins; Neutrophils; Phagocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
The myeloid leukemia cell line HL-60 produces a factor that induces chloride secretion in cultured epithelial cells.
Topics: Cells, Cultured; Chlorides; Epithelium; Humans; Leukemia, Promyelocytic, Acute; Neutrophils; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
Fatty acid changes during the induction of differentiation of human promyelocytic leukemia (HL-60) cells by phorbolmyristate acetate.
Topics: Cell Differentiation; Cyclooxygenase Inhibitors; Fatty Acids; Free Radicals; Humans; Leukemia, Promyelocytic, Acute; Lipoxygenase Inhibitors; Macrophages; Male; Membrane Lipids; Phospholipids; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
Redistribution of nuclear lamin A is an early event associated with differentiation of human promyelocytic leukemia HL-60 cells.
Topics: Bromodeoxyuridine; Cell Differentiation; Cell Nucleus; Cycloheximide; Humans; Immunoblotting; Lamin Type A; Lamin Type B; Lamins; Leukemia, Promyelocytic, Acute; Macrophages; Nuclear Proteins; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vimentin | 1992 |
Involvement of reactive oxygen intermediates in the induction of c-jun gene transcription by ionizing radiation.
Topics: Cell Nucleus; Cesium Radioisotopes; Clone Cells; Dactinomycin; Gamma Rays; Gene Expression Regulation, Neoplastic; Genes, fos; Genes, jun; Humans; Isoenzymes; Leukemia, Promyelocytic, Acute; Protein Kinase C; Restriction Mapping; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1992 |
Differentiation-induced changes in protein-tyrosine phosphatase activity and commensurate expression of CD45 in human leukemia cell lines.
Topics: Antigens, CD; Cell Differentiation; Dimethyl Sulfoxide; Electrophoresis; Histocompatibility Antigens; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Promyelocytic, Acute; Leukocyte Common Antigens; Protein Tyrosine Phosphatases; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
Expression of intermediate filament proteins in TPA-induced MPC-11 and HL-60 cells.
Topics: Animals; Blotting, Western; Cell Differentiation; Cell Division; Fluorescent Antibody Technique; Humans; Intermediate Filament Proteins; Kinetics; Lamin Type A; Lamin Type B; Lamins; Leukemia, Promyelocytic, Acute; Mice; Nuclear Proteins; Phenotype; Plasmacytoma; Tetradecanoylphorbol Acetate; Thymidine; Tumor Cells, Cultured; Vimentin | 1992 |
Changes in the phosphorylation status of a 19 kD cytosolic protein are linked to the growth arrest of HL-60 cells.
Topics: Cell Differentiation; Cell Division; Cytosol; Humans; Leukemia, Promyelocytic, Acute; Microtubule Proteins; Neoplasm Proteins; Phosphoproteins; Phosphorylation; Stathmin; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
A gene coding for a zinc finger protein is induced during 12-O-tetradecanoylphorbol-13-acetate-stimulated HL-60 cell differentiation.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cell Differentiation; DNA-Binding Proteins; Humans; Leukemia, Promyelocytic, Acute; Mice; Molecular Sequence Data; Rats; Tetradecanoylphorbol Acetate; Transcription Factors; Tumor Cells, Cultured; Zinc Fingers | 1992 |
A synthetic ceramide analog, D-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol, selectively inhibits adherence during macrophage differentiation of human leukemia cells.
Topics: Antineoplastic Agents; Cell Adhesion; Cell Differentiation; Cell Division; Cell Line; Ceramides; Glycosphingolipids; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Macrophages; Morpholines; Tetradecanoylphorbol Acetate | 1992 |
Inhibition of tumor necrosis factor-alpha (TNF-alpha) and interleukin-1 beta (IL-1 beta) messenger RNA (mRNA) expression in HL-60 leukemia cells by pentoxifylline and dexamethasone: dissociation of acivicin-induced TNF-alpha and IL-1 beta mRNA expression
Topics: Cell Differentiation; Dexamethasone; Esterases; Gene Expression; Genes, myc; Humans; Hydrogen Peroxide; Interleukin-1; Isoxazoles; Leukemia, Promyelocytic, Acute; Pentoxifylline; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myb; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1992 |
Inhibition of cellular transport systems by alkyl phospholipid analogs in HL-60 human leukemia cells.
Topics: Antineoplastic Agents; Biological Transport; Cell Line; Cell Survival; Choline; Humans; Leukemia, Promyelocytic, Acute; Monosaccharide Transport Proteins; Phosphatidylcholines; Phospholipid Ethers; Tetradecanoylphorbol Acetate | 1992 |
Transcriptional activation of human (2'-5')oligoadenylate synthetase gene expression by the phorbol ester 12-O-tetradecanoyl-phorbol 13-acetate in type-I-interferon-treated HL-60 and HeLa cells.
Topics: 2',5'-Oligoadenylate Synthetase; Cell Line; Cell Nucleus; Enzyme Induction; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; HeLa Cells; Humans; Interferon alpha-2; Interferon-alpha; Interferon-beta; Kinetics; Leukemia, Promyelocytic, Acute; Molecular Weight; Recombinant Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1992 |
CD4 gene transcription is transiently repressed during differentiation of myeloid cells to macrophage-like cells.
Topics: Blotting, Northern; CD4 Antigens; Cell Differentiation; Gene Expression Regulation, Neoplastic; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Lymphoma, Large B-Cell, Diffuse; Macrophages; Monocytes; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Transcription, Genetic | 1992 |
Myeloperoxidase is a primary response gene in HL60 cells, directly regulated during hematopoietic differentiation.
Topics: Blotting, Northern; Cell Differentiation; Cell Line; Cycloheximide; Gene Expression; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Leukemia, Promyelocytic, Acute; Peroxidase; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1991 |
Disassociation of the macrophage-maturational effects of vitamin D from respiratory burst priming.
Topics: Antineoplastic Agents; Calcitriol; Calcium; Cell Differentiation; Cell Line; Cytoplasm; Humans; Leukemia, Promyelocytic, Acute; Macrophages; N-Formylmethionine Leucyl-Phenylalanine; Receptors, Calcitriol; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Steroid; Superoxides; Tetradecanoylphorbol Acetate | 1991 |
Barbiturates enhance retinoic acid or 1,25-dihydroxyvitamin D3-induced differentiation of leukemia HL-60 cells.
Topics: Alkaloids; Barbiturates; Bucladesine; Calcitriol; Cell Differentiation; Cell Line; Dactinomycin; Dimethyl Sulfoxide; Granulocytes; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Macrophages; Monocytes; Pentobarbital; Protein Kinase C; Staurosporine; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Tretinoin | 1991 |
Chronic treatment with P2-purinergic receptor agonists induces phenotypic modulation of the HL-60 and U937 human myelogenous leukemia cell lines.
Topics: Actins; Adenosine; Adenosine Triphosphate; Calcium; Cell Differentiation; Cell Division; Cell Line; Genes, myc; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Lymphoma, Large B-Cell, Diffuse; N-Formylmethionine Leucyl-Phenylalanine; Phagocytes; Phenotype; Receptors, Purinergic; RNA, Messenger; Superoxides; Tetradecanoylphorbol Acetate; Uridine Triphosphate | 1991 |
The human promyelocytic HL60 cell line: a model of myeloid cell differentiation using dimethylsulphoxide, phorbol ester and butyrate.
Topics: Butyrates; Butyric Acid; Cell Differentiation; Cytochrome c Group; Dimethyl Sulfoxide; Hematopoietic Stem Cells; Humans; Leukemia, Promyelocytic, Acute; Leukocytes, Mononuclear; Luminescent Measurements; Lysosomes; Models, Biological; Neutrophils; Nitroblue Tetrazolium; Oxidation-Reduction; Phenotype; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
Optimization of transient transfection into human myeloid cell lines using a luciferase reporter gene.
Topics: Avian Sarcoma Viruses; Cell Differentiation; Cytomegalovirus; Electricity; Gene Expression Regulation; Granulocytes; Hematopoietic Stem Cells; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Luciferases; Plasmids; Promoter Regions, Genetic; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1991 |
Analysis of leukotriene B4 metabolism in human promyelocytic HL-60 cells.
Topics: Chromatography, Gel; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Gas Chromatography-Mass Spectrometry; Humans; Leukemia, Promyelocytic, Acute; Leukotriene B4; Luminescent Measurements; Nitroblue Tetrazolium; Oxidation-Reduction; Oxidoreductases; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
ADP-ribosylation of a small size GTP-binding protein in bovine neutrophils by the C3 exoenzyme of Clostridium botulinum and effect on the cell motility.
Topics: Adenosine Diphosphate Ribose; Animals; Cattle; Cell Line; Chemotaxis, Leukocyte; Clostridium botulinum; GTP-Binding Proteins; Humans; Leukemia, Promyelocytic, Acute; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Poly(ADP-ribose) Polymerases; Respiratory Burst; Superoxides; Tetradecanoylphorbol Acetate; Tubulin | 1991 |
Effects of protein kinase A and calcium/phospholipid-dependent kinase modulators in the process of HL-60 cell differentiation: their opposite effects between HL-60 cell and K-562 cell differentiation.
Topics: Alkaloids; Calcium; Cell Differentiation; Cell Line; Cholecalciferol; Diglycerides; Enzyme Activation; Gene Expression Regulation; Isoquinolines; Leukemia, Promyelocytic, Acute; Magnesium; Muramidase; Phenotype; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate | 1991 |
Interferon alpha-induced modulation of leukocyte cell surface antigens: immunocytofluorometric study with human leukaemia/lymphoma cell lines.
Topics: Antigens, CD; Antigens, Differentiation; Antigens, Neoplasm; Antigens, Surface; Gene Expression Regulation, Neoplastic; Humans; Interferon alpha-2; Interferon-alpha; Leukemia, Erythroblastic, Acute; Leukemia, Promyelocytic, Acute; Leukocytes; Lymphoma, Large B-Cell, Diffuse; Neprilysin; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Receptors, Transferrin; Recombinant Proteins; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
Changes in the levels of inositol lipids and phosphates during the differentiation of HL60 promyelocytic cells towards neutrophils or monocytes.
Topics: Cell Differentiation; Dimethyl Sulfoxide; Humans; Inositol; Inositol Phosphates; Leukemia, Promyelocytic, Acute; Lipid Metabolism; Monocytes; Neutrophils; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
An antisense oligodeoxynucleotide targeted against the type II beta regulatory subunit mRNA of protein kinase inhibits cAMP-induced differentiation in HL-60 leukemia cells without affecting phorbol ester effects.
Topics: Base Sequence; Cell Differentiation; Cell Division; Cell Line; Cyclic AMP; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Molecular Sequence Data; Oligodeoxyribonucleotides; Protein Kinases; Receptors, Cyclic AMP; RNA; RNA, Antisense; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Rapid neutrophil adhesion to activated endothelium mediated by GMP-140.
Topics: Antibodies; Calcium; Cell Adhesion; Cell Line; DNA; Endothelium; Histamine; Humans; Leukemia, Promyelocytic, Acute; Neutrophils; P-Selectin; Platelet Membrane Glycoproteins; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1990 |
Inducible gene expression of activin A/erythroid differentiation factor in HL-60 cells.
Topics: Activins; Cell Differentiation; Cell Line; Gene Expression; Humans; Inhibins; Leukemia, Promyelocytic, Acute; Lipopolysaccharides; Macromolecular Substances; Poly A; RNA; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tretinoin | 1990 |
Effects of antineoplastic phospholipids on parameters of cell differentiation in U937 cells.
Topics: Antigens, Surface; Antineoplastic Agents; Blotting, Northern; Cell Transformation, Neoplastic; DNA Probes; Fatty Alcohols; Gene Expression Regulation, Neoplastic; Histones; Leukemia, Promyelocytic, Acute; Lysophosphatidylcholines; Phorbol Esters; Phospholipid Ethers; Phospholipids; Phosphorylcholine; RNA; RNA, Messenger; Tetradecanoylphorbol Acetate | 1990 |
Modulation of the constitutive gene expression of the 55 kD tumor necrosis factor receptor in hematopoietic cells.
Topics: 1-Methyl-3-isobutylxanthine; Bucladesine; Carcinoma, Hepatocellular; Colforsin; Gene Expression Regulation; Humans; Leukemia, Promyelocytic, Acute; Leukocytes, Mononuclear; Liver Neoplasms; Molecular Weight; Neutrophils; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Receptors, Cell Surface; Receptors, Tumor Necrosis Factor; Recombinant Proteins; Reference Values; RNA; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Necrosis Factor-alpha | 1990 |
Promyelocytic leukemia cell line, HL-60, produces human hepatocyte growth factor.
Topics: Amino Acids; Animals; Cell Line; Cells, Cultured; Chromatography, High Pressure Liquid; Culture Media; DNA Replication; Enzyme-Linked Immunosorbent Assay; Growth Substances; Hepatocyte Growth Factor; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Liver; Poly A; Rats; RNA; RNA, Messenger; Tetradecanoylphorbol Acetate | 1991 |
Protein kinases negatively affect nuclear factor-kappa B activation by tumor necrosis factor-alpha at two different stages in promyelocytic HL60 cells.
Topics: Alkaloids; Blotting, Northern; Cell Line; Cell Nucleus; Cytosol; Humans; Interleukin-1; Kinetics; Leukemia, Promyelocytic, Acute; Macromolecular Substances; NF-kappa B; Phosphorylation; Protein Kinase Inhibitors; Protein Kinases; Recombinant Proteins; RNA, Messenger; RNA, Neoplasm; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1992 |
Induced differentiation of HL-60 promyelocytic leukemia cells to monocyte/macrophages is inhibited by hydroquinone, a hematotoxic metabolite of benzene.
Topics: Benzene Derivatives; Benzoquinones; Calcitriol; Cell Differentiation; Dose-Response Relationship, Drug; Granulocytes; Humans; Hydroquinones; In Vitro Techniques; Interleukin-1; Leukemia, Promyelocytic, Acute; Macrophages; Monocytes; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1992 |
Sustained activation of protein kinase C is essential to HL-60 cell differentiation to macrophage.
Topics: Biological Transport; Cell Differentiation; Cell Line; Diglycerides; Enzyme Activation; Flow Cytometry; Humans; Isoenzymes; Kinetics; Leukemia, Promyelocytic, Acute; Macrophage-1 Antigen; Macrophages; Phagocytosis; Protein Kinase C; Tetradecanoylphorbol Acetate | 1991 |
Dexamethasone and phorbol ester, but not cytokines, increase the production of plasminogen activator inhibitor type-2 in the PL-21 human promyelocytic leukemia cell line.
Topics: Cytokines; Dexamethasone; Humans; Leukemia, Promyelocytic, Acute; Plasminogen Inactivators; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
Identification of sphingomyelin turnover as an effector mechanism for the action of tumor necrosis factor alpha and gamma-interferon. Specific role in cell differentiation.
Topics: Bucladesine; Cell Differentiation; Cell Line; Ceramides; Humans; Interferon-gamma; Kinetics; Leukemia, Promyelocytic, Acute; Recombinant Proteins; Sphingomyelin Phosphodiesterase; Sphingomyelins; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Necrosis Factor-alpha | 1991 |
Mechanism of transient increase in intracellular concentration of free calcium ions in HL-60 cell differentiation induced by vitamin D3 and phorbol ester.
Topics: Calcitriol; Calcium; Cell Differentiation; Dimethyl Sulfoxide; Fura-2; Granulocytes; Humans; Leukemia, Promyelocytic, Acute; Macrophages; Monocytes; Protein Kinase C; Spectrophotometry, Ultraviolet; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1991 |
1 alpha,25-dihydroxyvitamin D3-induced regulation of protein kinase C gene expression during HL-60 cell differentiation.
Topics: Calcitriol; Cell Differentiation; Enzyme Induction; Gene Expression Regulation, Leukemic; Humans; Isoenzymes; Leukemia, Promyelocytic, Acute; Monocytes; Neoplasm Proteins; Protein Kinase C; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
[Retinoic acid and 12-0-tetradecanoylphorbol-13-acetate (TPA) inducing bipotent differentiation of cultured primary bone marrow cells from leukemia patients].
Topics: Bone Marrow; Cell Differentiation; Drug Synergism; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Promyelocytic, Acute; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1991 |
The role of inositol transport in cellular differentiation.
Topics: Biological Transport; Cell Differentiation; Cell Line; Dimethyl Sulfoxide; Humans; Inositol; Kinetics; Leukemia, Promyelocytic, Acute; Tetradecanoylphorbol Acetate | 1991 |
Expression of c-jun during macrophage differentiation of HL-60 cells.
Topics: Calcitriol; Cell Differentiation; DNA-Binding Proteins; Gene Expression; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Macrophages; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription Factors; Tretinoin; Tumor Cells, Cultured | 1991 |
Stimulation of synthesis de novo of NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase in human promyelocytic leukaemia (HL-60) cells by phorbol ester.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Blotting, Western; Dimethyl Sulfoxide; Dinoprostone; Enzyme Activation; Enzyme Induction; Humans; Hydroxyprostaglandin Dehydrogenases; Isoquinolines; Kinetics; Leukemia, Promyelocytic, Acute; NAD; Piperazines; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
Daily addition of an anti-c-myc DNA oligomer induces granulocytic differentiation of human promyelocytic leukemia HL-60 cells in both serum-containing and serum-free media.
Topics: Blood; Cell Differentiation; Cell Division; Culture Media; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Genes, myc; Granulocytes; Humans; Leukemia, Promyelocytic, Acute; Oligonucleotides, Antisense; Proto-Oncogene Proteins c-myc; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
Differentiation of HL-60 leukemia by type I regulatory subunit antisense oligodeoxynucleotide of cAMP-dependent protein kinase.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Base Sequence; Cell Differentiation; Cell Division; Cell Line; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Macromolecular Substances; Molecular Sequence Data; Oligonucleotides, Antisense; Protein Kinases; Tetradecanoylphorbol Acetate | 1991 |
Induction of the differentiation of HL-60 cells by phorbol 12-myristate 13-acetate activates a Na(+)-dependent uridine-transport system. Involvement of protein kinase C.
Topics: Alkaloids; Biological Transport; Cell Differentiation; Cell Line; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Protein Kinase C; Ribonucleosides; Sodium; Staurosporine; Tetradecanoylphorbol Acetate; Uridine | 1991 |
Effects of hexadecylphosphocholine on protein kinase C and TPA-induced differentiation of HL60 cells.
Topics: Cell Differentiation; Cell Line; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Phospholipid Ethers; Phosphoproteins; Phosphorylation; Phosphorylcholine; Protein Kinase C; Tetradecanoylphorbol Acetate | 1991 |
A differential effect of phorbol ester on the internalization of iron and transferrin by HL 60 cells.
Topics: Biological Transport; Cell Line; Humans; Iodine Radioisotopes; Iron; Iron Radioisotopes; Kinetics; Leukemia, Promyelocytic, Acute; Tetradecanoylphorbol Acetate; Transferrin | 1990 |
Transcriptional and post-transcriptional regulation of c-jun expression during monocytic differentiation of human myeloid leukemic cells.
Topics: Calcitriol; Cell Differentiation; Cell Line; Cycloheximide; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; Humans; Leukemia, Promyelocytic, Acute; Lymphoma, Large B-Cell, Diffuse; Monocytes; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-jun; Proto-Oncogenes; RNA Processing, Post-Transcriptional; Tetradecanoylphorbol Acetate; Transcription Factors; Transcription, Genetic | 1990 |
Differential changes in lipid metabolism of myeloid and lymphoid cell lines induced by treatment with 12-O-tetradecanoylphorbol-13-acetate (TPA).
Topics: Arachidonic Acid; Arachidonic Acids; Cell Line; Glycerides; Glycerol; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Lipid Metabolism; Lymphoma, Large B-Cell, Diffuse; Tetradecanoylphorbol Acetate | 1990 |
The role of the c-fms oncogene in the regulation of HL-60 cell differentiation.
Topics: Base Sequence; Calcitriol; Cell Transformation, Neoplastic; Colony-Stimulating Factors; Dimethyl Sulfoxide; Gene Expression; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Substances; Humans; Leukemia, Promyelocytic, Acute; Macrophage Colony-Stimulating Factor; Macrophages; Molecular Sequence Data; Oligonucleotides; Polymerase Chain Reaction; Proto-Oncogene Proteins; Receptor, Macrophage Colony-Stimulating Factor; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 1990 |
Modulation of retinoic acid-induced differentiation of human leukemia (HL-60) cells by serum factors and sphinganine.
Topics: Blood Physiological Phenomena; Cell Differentiation; Humans; Leukemia, Promyelocytic, Acute; N-Formylmethionine Leucyl-Phenylalanine; Protein Kinase C; Sphingosine; Superoxides; Tetradecanoylphorbol Acetate; Tretinoin | 1990 |
PAF-acether transfer activity in HL-60 cells is induced during differentiation.
Topics: Bucladesine; Cell Differentiation; Cell Line; Chromatography, Gel; Cytosol; Dimethyl Sulfoxide; Granulocytes; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Macrophages; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Tetradecanoylphorbol Acetate | 1990 |
Physiological cyclic AMP stimulation and oncogene mRNA levels in HL-60 cells.
Topics: Base Sequence; Cyclic AMP; Gene Expression; Humans; Isoproterenol; Leukemia, Promyelocytic, Acute; Molecular Sequence Data; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-myc; Proto-Oncogenes; RNA, Messenger; Tetradecanoylphorbol Acetate; Theophylline; Tumor Cells, Cultured | 1990 |
Control of interleukin-1 beta expression by protein kinase C and cyclic adenosine monophosphate in myeloid leukemia cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Bucladesine; Colforsin; Cyclic AMP; Dinoprostone; Enzyme Activation; Gene Expression; Humans; Interleukin-1; Isoquinolines; Leukemia, Myeloid; Leukemia, Promyelocytic, Acute; Piperazines; Protein Kinase C; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Induction of cyclo-oxygenase synthesis in human promyelocytic leukaemia (HL-60) cells during monocytic or granulocytic differentiation.
Topics: Calcitriol; Cell Differentiation; Cell Line; Electron Transport Complex IV; Enzyme Induction; Granulocytes; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Monocytes; Prostaglandin-Endoperoxide Synthases; Tetradecanoylphorbol Acetate; Tretinoin | 1990 |
Direct and cytokine-mediated activation of protein kinase C induces human immunodeficiency virus expression in chronically infected promonocytic cells.
Topics: Biological Factors; Bryostatins; Cell Line; Cell Nucleus; Cytokines; Diglycerides; Enzyme Activation; Guanosine Triphosphate; HIV; Humans; Lactones; Leukemia, Promyelocytic, Acute; Macrolides; Mitogens; Protein Kinase C; Recombinant Proteins; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Viral Proteins; Virus Replication | 1990 |
Effect of phorbol myristate acetate on c-myc, beta-actin, and FV gene expression in morphologically recognizable human megakaryocytes: a kinetic analysis employing in situ hybridization.
Topics: Actins; Bone Marrow Cells; Cells, Cultured; DNA Probes; Factor V; Gene Expression; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Megakaryocytes; Nucleic Acid Hybridization; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myc; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Analysis of nuclear sugar-binding components in undifferentiated and in vitro differentiated human promyelocytic leukemia cells (HL60).
Topics: Carrier Proteins; Cell Differentiation; Cell Nucleus; Cell Transformation, Neoplastic; Dimethyl Sulfoxide; DNA; Fluorescein; Fluoresceins; Humans; Lectins; Leukemia, Promyelocytic, Acute; Microscopy, Fluorescence; Nuclear Proteins; Phenotype; Receptors, Cell Surface; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
1,25-Dihydroxyvitamin D3 enhances cytosolic free calcium in HL-60 cells.
Topics: Calcitriol; Calcium; Cell Differentiation; Cell Division; Cytosol; Fluorescent Antibody Technique; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Spectrometry, Fluorescence; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vitamin D | 1990 |
Myeloid leukemia differentiation by phorbol ester and retinoic acid: a practical approach.
Topics: Cell Transformation, Neoplastic; Diagnosis, Differential; Humans; Leukemia, Erythroblastic, Acute; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid; Leukemia, Promyelocytic, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tetradecanoylphorbol Acetate; Tretinoin | 1990 |
Measurement of oxidized proteins in systems involving activated neutrophils or HL-60 cells.
Topics: Blood Proteins; Cell Differentiation; Cell Line; Humans; Leukemia, Promyelocytic, Acute; Neoplasm Proteins; Neutrophils; Oxidation-Reduction; Phenylhydrazines; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Differential effect of 6-ethylmercaptopurine on c-myc expression in wild-type and HGPRT-deficient HL-60 cells.
Topics: Cell Differentiation; Gene Expression; Genes, fms; Genes, myc; Humans; Hypoxanthine Phosphoribosyltransferase; Leukemia, Promyelocytic, Acute; Mercaptopurine; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Expression of human proliferation-associated nucleolar antigen p120.
Topics: Cell Differentiation; Cell Division; Gene Expression Regulation; Half-Life; Histones; Humans; Interphase; Leukemia, Promyelocytic, Acute; Leukocytes, Mononuclear; Lymphocyte Activation; Nuclear Proteins; Phytohemagglutinins; Proto-Oncogene Proteins c-myc; RNA, Messenger; Tetradecanoylphorbol Acetate; tRNA Methyltransferases; Tumor Cells, Cultured | 1990 |
Regulation of the relative abundances of c-myc mRNAs in human promyelocytic HL60 cells.
Topics: Cell Transformation, Neoplastic; Dimethyl Sulfoxide; Gene Expression Regulation, Neoplastic; Humans; Leukemia, Promyelocytic, Acute; Promoter Regions, Genetic; Proto-Oncogene Proteins c-myc; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 1990 |
Transcriptional regulation of protein kinase C by 1,25-dihydroxyvitamin D3 in HL-60 cells.
Topics: Caenorhabditis elegans Proteins; Calcitriol; Carrier Proteins; Cell Line; Gene Expression Regulation, Enzymologic; Genes; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Phorbol 12,13-Dibutyrate; Protein Kinase C; Receptors, Drug; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 1990 |
Cytosolic-nuclear tumor promoter-specific binding protein (CN-TPBP) in human promyelocytic leukemia cells HL-60.
Topics: Binding, Competitive; Caenorhabditis elegans Proteins; Carrier Proteins; Cell Line; Cell Nucleus; Chromatography, High Pressure Liquid; Cytosol; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Protein Binding; Protein Kinase C; Receptors, Drug; Tetradecanoylphorbol Acetate | 1990 |
Marked alteration in phosphorylation of the RB protein during differentiation of human promyelocytic HL60 cells.
Topics: Antigens, Polyomavirus Transforming; Cell Differentiation; Humans; Leukemia, Promyelocytic, Acute; Neoplasm Proteins; Phosphorylation; Retinoblastoma; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Post-transcriptional regulation of thymidine kinase gene expression during monocytic differentiation of HL60 promyelocytes.
Topics: Cell Differentiation; Cell Line; Cell Nucleus; Dactinomycin; DNA Probes; Gene Expression Regulation, Enzymologic; Genes; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Monocytes; Nucleic Acid Hybridization; RNA Processing, Post-Transcriptional; RNA, Messenger; Tetradecanoylphorbol Acetate; Thymidine Kinase; Transcription, Genetic; Tumor Cells, Cultured | 1990 |
Diadenosine tetraphosphate (Ap4A) levels in HL-60 cells during differentiation into granulocytes and monocytes.
Topics: Cell Differentiation; Dinucleoside Phosphates; Granulocytes; Humans; Leukemia, Promyelocytic, Acute; Monocytes; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1990 |
Differential expression of cytosolic activation factors for NADPH oxidase in HL-60 leukemic cells.
Topics: Arachidonic Acid; Arachidonic Acids; Bucladesine; Calcimycin; Cell Differentiation; Cell Line; Cytosol; Dimethyl Sulfoxide; Enzyme Activation; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Hexachlorocyclohexane; Humans; Kinetics; Leukemia, Promyelocytic, Acute; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Superoxides; Tetradecanoylphorbol Acetate; Thionucleotides | 1989 |
Modulation of ornithine decarboxylase gene transcript levels by differentiation inducers in human promyelocytic leukemia HL60 cells.
Topics: Bucladesine; Calcitriol; Cell Line; Cell Transformation, Neoplastic; Dimethyl Sulfoxide; Gene Expression; Humans; Leukemia, Promyelocytic, Acute; Ornithine Decarboxylase; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myc; RNA; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tretinoin | 1989 |
Role of arachidonic acid metabolism in transcriptional induction of tumor necrosis factor gene expression by phorbol ester.
Topics: Arachidonic Acid; Arachidonic Acids; Dexamethasone; DNA-Binding Proteins; Gene Expression Regulation; Humans; Leukemia, Promyelocytic, Acute; Protein Kinase C; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1989 |
Regulation of phospholipase D in HL-60 granulocytes. Activation by phorbol esters, diglyceride, and calcium ionophore via protein kinase- independent mechanisms.
Topics: Calcimycin; Cell Line; Diglycerides; Enzyme Activation; Glycerides; Granulocytes; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Phorbol 12,13-Dibutyrate; Phospholipase D; Phospholipases; Protein Kinase C; Tetradecanoylphorbol Acetate | 1989 |
Heterogenous response of primary cultured bone marrow cells of patients with different varieties of leukemia to differentiation inducers.
Topics: Adolescent; Adult; Aged; Bone Marrow; Child; Female; Harringtonines; Homoharringtonine; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1989 |
Differentiation-linked expression of the plasminogen activator inhibitor type-2 gene in the human HL-60 promyelocytic cell line.
Topics: Cell Differentiation; Cell Line; Gene Expression Regulation, Neoplastic; Genes; Humans; Leukemia, Promyelocytic, Acute; Plasminogen Inactivators; Pregnancy Proteins; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
Involvement of intracellular pH elevation in the effect of 1,25-dihydroxyvitamin D3 on HL-60 cells.
Topics: Ammonium Chloride; Calcitriol; Carrier Proteins; Cell Differentiation; Cell Division; Humans; Hydrogen-Ion Concentration; Leukemia, Promyelocytic, Acute; Monocytes; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
Studies of signal transduction in the respiratory burst-associated stimulation of fMet-Leu-Phe-induced tubulin tyrosinolation and phorbol 12-myristate 13-acetate-induced posttranslational incorporation of tyrosine into multiple proteins in activated neutr
Topics: Cell Line; Diglycerides; Humans; In Vitro Techniques; Kinetics; Leukemia, Promyelocytic, Acute; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Protein Kinase C; Protein Processing, Post-Translational; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate; Tubulin; Tyrosine | 1989 |
Novobiocin- and phorbol-12-myristate-13-acetate-induced differentiation of human leukemia cells associated with a reduction in topoisomerase II activity.
Topics: Amsacrine; Cell Differentiation; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Humans; Leukemia, Promyelocytic, Acute; Novobiocin; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate | 1989 |
Sphingomyelinase action inhibits phorbol ester-induced differentiation of human promyelocytic leukemic (HL-60) cells.
Topics: Cell Adhesion; Cell Differentiation; Cell Division; Humans; Leukemia, Promyelocytic, Acute; Phosphoric Diester Hydrolases; Protein Kinase C; Sphingolipids; Sphingomyelin Phosphodiesterase; Sphingosine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
Rapid increase in the activity of DNA topoisomerase I, but not topoisomerase II, in HL-60 promyelocytic leukemia cells treated with a phorbol diester.
Topics: Camptothecin; Cell Line; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Enzyme Activation; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
Phorbol ester inhibits polyphosphoinositide phosphodiesterase activity stimulated by either Ca2+, fluoride or GTP analogue in HL60 membranes and in permeabilized HL60 cells.
Topics: Calcium; Cell Membrane; Cell Membrane Permeability; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Phosphoinositide Phospholipase C; Phosphoric Diester Hydrolases; Protein Kinase C; Tetradecanoylphorbol Acetate; Thionucleotides; Tumor Cells, Cultured | 1989 |
Characterization of nucleoside transport during leukemic cell differentiation.
Topics: Biological Transport; Cell Differentiation; Cytarabine; Deoxycytidine Kinase; Dipyridamole; Humans; Inosine; Leukemia, Promyelocytic, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thioinosine; Tretinoin; Tumor Cells, Cultured | 1989 |
Reversal of enzymic phenotype of thymidine metabolism in induced differentiation of HL-60 cells.
Topics: Cell Cycle; Cell Differentiation; Dihydrouracil Dehydrogenase (NAD+); DNA; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Tetradecanoylphorbol Acetate; Thymidine; Tumor Cells, Cultured | 1989 |
Combined procoagulant activity and proteolytic activity of acute promyelocytic leukemic cells: reversal of the bleeding disorder by cell differentiation.
Topics: Blood Coagulation; Cell Differentiation; Fibrinolysis; Humans; In Vitro Techniques; Leukemia, Promyelocytic, Acute; Pancreatic Elastase; Peptide Hydrolases; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
Anti-c-myc DNA increases differentiation and decreases colony formation by HL-60 cells.
Topics: Cell Differentiation; Cell Division; Dimethyl Sulfoxide; Drug Synergism; Granulocytes; Histocytochemistry; Humans; Leukemia, Promyelocytic, Acute; Nitroblue Tetrazolium; Oligonucleotides; Oligonucleotides, Antisense; Oxidation-Reduction; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myc; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
Regulation of the mRNA for monocyte-derived neutrophil-activating peptide in differentiating HL60 promyelocytes.
Topics: Amino Acid Sequence; Base Sequence; Cell Differentiation; Chemotactic Factors; DNA; Gene Expression Regulation; Granulocytes; Humans; Interleukin-8; Leukemia, Promyelocytic, Acute; Molecular Sequence Data; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 1989 |
Two promoters that map to 5'-sequences of the human p53 gene are differentially regulated during terminal differentiation of human myeloid leukemic cells.
Topics: Cell Cycle; Cell Differentiation; Cloning, Molecular; Dimethyl Sulfoxide; Gene Expression Regulation; Granulocytes; Hematopoiesis; Leukemia, Promyelocytic, Acute; Monocytes; Neoplasm Proteins; Phosphoproteins; Promoter Regions, Genetic; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 1989 |
Absence of phorbol ester-induced down-regulation of myc protein in the phorbol ester-tolerant mutant of HL-60 promyelocytes.
Topics: Blotting, Southern; Cell Differentiation; Dimethyl Sulfoxide; Gene Amplification; Gene Expression Regulation; Humans; Leukemia, Promyelocytic, Acute; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myc; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
1,25-Dihydroxyvitamin D3 regulation of c-myc protooncogene transcription. Possible involvement of protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Calcitriol; Cell Differentiation; Cell Line; Cell Nucleus; Ethanol; Gene Expression Regulation, Neoplastic; Humans; Isoquinolines; Kinetics; Leukemia, Promyelocytic, Acute; Piperazines; Protein Kinase C; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myc; Proto-Oncogenes; Sphingosine; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 1989 |
Expression of vimentin and nuclear lamins during the in vitro differentiation of human promyelocytic leukemia cells HL-60.
Topics: Blotting, Northern; Cell Differentiation; Dimethyl Sulfoxide; Fluorescent Antibody Technique; Granulocytes; Hematopoiesis; Humans; Lamin Type A; Lamin Type B; Lamins; Leukemia, Promyelocytic, Acute; Macrophages; Nuclear Proteins; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured; Vimentin | 1989 |
Mechanism of the induction of the differentiation of HL-60 leukemia cells by antifolates.
Topics: Antibodies, Monoclonal; Cell Differentiation; Cell Division; Cell Line; Dimethyl Sulfoxide; DNA Replication; Flow Cytometry; Fluorescent Antibody Technique; Folic Acid Antagonists; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Ribonucleotides; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Thymidine; Tretinoin; Tumor Cells, Cultured | 1989 |
Differential effects of long-chain (sphingoid) bases on the monocytic differentiation of human leukemia (HL-60) cells induced by phorbol esters, 1 alpha, 25-dihydroxyvitamin D3, or ganglioside GM3.
Topics: Antigens, Neoplasm; Antigens, Surface; Calcitriol; Cell Differentiation; Cell Division; Cell Line; Cell Survival; G(M3) Ganglioside; Gangliosides; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Sphingosine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
Decrease in CuZn-superoxide dismutase mRNA level during differentiation of human monocytic and promyelotic leukemia cells.
Topics: Blotting, Northern; Cell Differentiation; Copper; Dimethyl Sulfoxide; Fibroblasts; Humans; Leukemia, Monocytic, Acute; Leukemia, Promyelocytic, Acute; Nucleic Acid Hybridization; RNA, Messenger; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Zinc | 1989 |
Alteration of intracellular actin levels induced by phorboldiester in human HL-60 leukemia cells susceptible or resistant to differentiation, and the effects of protein kinase inhibitors.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actins; Alkaloids; Antibodies, Monoclonal; Antigen-Antibody Reactions; Cell Differentiation; Cell Line; Cytoplasm; Drug Resistance; Humans; Isoquinolines; Leukemia, Promyelocytic, Acute; Macrophages; Neoplasm Proteins; Phosphorylation; Piperazines; Protein Kinase Inhibitors; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
Synthetic diacylglycerols trigger an increase of intracellular free calcium in promyelocytic HL60 cells.
Topics: Benzofurans; Calcium; Cell Line; Cell Membrane Permeability; Diglycerides; Fura-2; Glycerides; Humans; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Leukemia, Promyelocytic, Acute; Potassium; Sodium; Spectrometry, Fluorescence; Tetradecanoylphorbol Acetate | 1989 |
Phorbol esters and chemotactic factor induce distinct changes in cytoplasmic Ca2+ and pH in granulocytic like HL60 cells.
Topics: Amiloride; Calcium; Cell Differentiation; Cell Line; Dimethyl Sulfoxide; Granulocytes; Humans; Hydrogen-Ion Concentration; Kinetics; Leukemia, Promyelocytic, Acute; N-Formylmethionine Leucyl-Phenylalanine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
Loss of copper-zinc superoxide dismutase gene expression in differentiated cells of myelo-monocytic origin.
Topics: Cell Differentiation; Cell Line; Diglycerides; Gene Expression; Genes; Humans; Kinetics; Leukemia, Erythroblastic, Acute; Leukemia, Promyelocytic, Acute; Macrophages; Monocytes; RNA, Messenger; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1989 |
Effect of phorbol ester treatment on drug-induced, topoisomerase II-mediated DNA cleavage in human leukemia cells.
Topics: Amsacrine; Chromatin; DNA; DNA Damage; DNA Topoisomerases, Type II; Etoposide; Humans; Leukemia, Promyelocytic, Acute; Proto-Oncogenes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1988 |
Activation of inositol phospholipid breakdown in HL60 cells by P2-purinergic receptors for extracellular ATP. Evidence for mediation by both pertussis toxin-sensitive and pertussis toxin-insensitive mechanisms.
Topics: Adenosine Triphosphate; Calcium; Cell Line; Cytosol; Humans; Inositol Phosphates; Kinetics; Leukemia, Promyelocytic, Acute; N-Formylmethionine Leucyl-Phenylalanine; Pertussis Toxin; Phosphatidylinositols; Receptors, Purinergic; Sodium Chloride; Sodium Fluoride; Sugar Phosphates; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1988 |
The degranulation response in differentiated HL-60 cells.
Topics: Calcimycin; Cell Differentiation; Cell Line; Cytoplasmic Granules; Granulocytes; Humans; Immunoglobulin G; Leukemia, Promyelocytic, Acute; N-Formylmethionine Leucyl-Phenylalanine; Pancreatic Elastase; Peroxidase; Tetradecanoylphorbol Acetate | 1988 |
Prostaglandin production by human promyelocytic leukemia (HL-60) cells.
Topics: Arachidonic Acid; Arachidonic Acids; Cell Differentiation; Cell Line; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Dimethyl Sulfoxide; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Prostaglandins; Tetradecanoylphorbol Acetate; Transglutaminases | 1988 |
Differentiating human leukemia cells express heparanase that degrades heparan sulfate in subendothelial extracellular matrix.
Topics: Cell Line; Extracellular Matrix; Glucuronidase; Glycosaminoglycans; Glycoside Hydrolases; Heparitin Sulfate; Humans; Leukemia, Monocytic, Acute; Leukemia, Promyelocytic, Acute; Molecular Weight; Plasminogen; Tetradecanoylphorbol Acetate | 1988 |
Molecular events induced in the HL 60 cell line following treatment with gamma-interferon.
Topics: Antigens, Surface; Cell Differentiation; Cell Line; DNA Probes; Flow Cytometry; Fluorescent Antibody Technique; Gene Expression Regulation; Humans; Interferon-gamma; Leukemia, Promyelocytic, Acute; Proto-Oncogenes; Tetradecanoylphorbol Acetate | 1988 |
Metallothionein RNA levels in HL-60 cells. Effect of cadmium, differentiation, and protein kinase C activation.
Topics: Amino Acid Sequence; Base Sequence; Cadmium; Calcimycin; Calcitriol; Cell Differentiation; Cell Line; Enzyme Activation; Humans; Leukemia, Promyelocytic, Acute; Metallothionein; Molecular Sequence Data; Oligonucleotide Probes; Protein Kinase C; RNA, Messenger; Tetradecanoylphorbol Acetate | 1988 |
Effects of thioether phospholipid BM 41.440 on protein kinase C and phorbol ester-induced differentiation of human leukemia HL60 and KG-1 cells.
Topics: Cell Differentiation; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Phospholipid Ethers; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1988 |
Heterogeneity of the response to inducers of differentiation and to cytostatics of tumor cell populations.
Topics: Antineoplastic Agents; Cell Differentiation; Cisplatin; Cytarabine; Dacarbazine; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Doxorubicin; Fluorouracil; Humans; Leukemia, Erythroblastic, Acute; Leukemia, Promyelocytic, Acute; Melanoma; Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1988 |