tetradecanoylphorbol acetate has been researched along with Acute Myelogenous Leukemia in 283 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 222 (78.45) | 18.7374 |
| 1990's | 32 (11.31) | 18.2507 |
| 2000's | 13 (4.59) | 29.6817 |
| 2010's | 15 (5.30) | 24.3611 |
| 2020's | 1 (0.35) | 2.80 |
| Authors | Studies |
|---|---|
| Bagnoli, JW; Blum, H; Chen-Wichmann, L; Cusan, M; Enard, W; Greif, PA; Hartmann, L; Hiddemann, W; Jeremias, I; Kerbs, P; Krebs, S; Leubolt, G; Redondo Monte, E; Theurich, S; Vick, B; Wichmann, C; Wilding, A | 1 |
| Guo, Q; Hui, H; Li, H; Li, Z; Liu, X; Shen, LE; Wang, X; Xu, J; Zhou, Y; Zhu, YU | 1 |
| Lam, CF; Lam, YM; Ng, RK; Yeung, HT | 1 |
| Bulabois, CE; Cahn, JY; Carras, S; Carré, M; Courby, S; Faure, P; Garrel, C; Gressin, R; Leer-Florin, AM; Mariette, C; Molina, L; Mondet, J; Mossuz, P; Park, S; Presti, CL; Skaare, K; Socoro-Yuste, N; Thiebaut, A | 1 |
| Chen, J; Gong, JN; Lin, HS; Liu, B; Ma, YN; Ning, HM; Shen, C; Song, L; Su, R; Wang, F; Yin, XL; Yu, J; Zhai, PF; Zhang, JW; Zhang, XH; Zhao, HL | 1 |
| Guo, M; Huang, Z; Li, D; Li, L; Li, W; Liang, Q; Lin, Y; Liu, S; Sun, X; Zuo, X | 1 |
| Duyster, J; Engelhardt, M; Ewerth, D; Greil, C; Hein, M; Kvainickas, A; Schmidts, A; Schnerch, D; Wäsch, R | 1 |
| Jin, H; Tan, S; Wang, J; Wang, L; Xian, J; Yang, L; Yang, Z; Zhang, L; Zhang, S; Zou, Q | 1 |
| Medina, DJ; Moore, DF; Schaar, DG; Strair, RK; Ting, Y | 1 |
| Kuromi, A; Shimizu, T; Takeda, K | 1 |
| Chen, GQ; Hou, JK; Huang, Y; Wu, SF; Yuan, TT; Zhang, J; Zhou, CX | 1 |
| Fujita, H; Hama, M; Ishigatsubo, Y; Kirino, Y; Miyazaki, T; Samukawa, S; Takeno, M; Tanaka, M; Tomita, N; Ueda, A; Yamaji, S | 1 |
| Chen, HL; Guo, XH; Qiu, H; Shen, HJ; Wu, SL; Zhang, HP | 1 |
| Chow, S; Hedley, DW; Shankey, TV | 1 |
| Gong, JN; Luo, ZM; Shen, C; Tan, ZQ; Wang, F; Wang, XS; Yang, GH; Yin, XL; Yu, J; Zhang, JW; Zhang, XH | 1 |
| Fàbregas, P; Félez, J; Jardí, M; Miles, LA; Parmer, RJ | 1 |
| Ding, YL; Ge, CH; Li, CY; Li, W; Lian, WX; Ning, HM; Xu, CW; Xu, WX; Yang, XM; Yang, Y; Yu, M; Zhan, YQ; Zhang, MJ | 1 |
| Bačíková, A; Falk, M; Grigoryev, S; Klabusay, M; Kohútová, V; Kořistek, Z; Kozubek, S; Lukášová, E; Ondřej, V; Řezáčová, M; Vávrová, J | 1 |
| Senou, M; Shimizu, T; Taira, N; Takeda, K | 1 |
| Chang, WH; Chen, ST; Juan, HF; Khoo, KH; Lin, JY; Pan, TL; Tseng, MJ; Wu, CY | 1 |
| Chang, RL; Conney, AH; Cui, XX; Strair, R; Woodward, D; Zheng, X | 1 |
| Kato, M; Kimura, H; Kobayashi, Y; Kozawa, K; Kuroiwa, M; Minakami, H; Morikawa, A; Oshima, S | 1 |
| Classen, CF; Debatin, KM; Gnekow, A | 1 |
| Eggen, BJ; Geugien, M; Schepers, H; Vellenga, E | 1 |
| Chow, S; Hedley, D; Tong, FK | 1 |
| Louache, F; Rochant, H; Testa, U; Thomopoulos, P; Titeux, M | 1 |
| Bödewadt, S; Frendel, A; Lennert, K; Parwaresch, MR; Radzun, HJ; Sundström, C | 1 |
| Christman, JK; Herzog, D; Mendelsohn, N; Schneiderman, N | 1 |
| Dowdle, EB; Jacobs, P; Wilson, EL | 2 |
| Dahlgren, C; Jacobson, K; Magnusson, KE; Stendahl, O; Sundqvist, T; Wojcieszyn, J | 1 |
| Bloch, A; Craig, RW | 1 |
| Henning, CB; Huberman, E; Ryffel, B | 1 |
| Fibach, E; Kidron, M; Mayer, M; Nachshon, I | 1 |
| Bar-Eli, M; Koeffler, HP; Territo, M | 1 |
| Baker, RD; Duncan, RA; Greenberger, JS; Hansen, SL; Newburger, PE | 1 |
| Adolf, W; Hecker, E; Nakayasu, M; Opferkuch, HJ; Schmidt, R; Sugimura, T; Terada, M | 1 |
| Bernal, SD; Chen, LB | 1 |
| Colburn, NH; Dalal, B; Gindhart, TD; Hegamyer, GA | 1 |
| Goodwin, BJ; Moore, JO; Weinberg, JB | 1 |
| Ballestrero, A; Dallegri, F; Frumento, G; Patrone, F; Sacchetti, C | 1 |
| Kato, R; Mita, S; Nakadate, T; Nakaki, T; Yamamoto, S | 1 |
| Albright, KL; Yen, A | 1 |
| Elias, L; Stewart, T | 1 |
| Harford, J; Klausner, RD; van Renswoude, J | 1 |
| Besterman, JM; Cuatrecasas, P | 1 |
| Billing, R; Bohman, R; Koeffler, HP; Ranyard, J; Yelton, L | 1 |
| Estensen, RD; Mascioli, DW | 1 |
| Burnett, D; Crocker, J; Vaughan, AT | 1 |
| Nagasawa, K | 1 |
| Minato, K; Minowada, J; Sagawa, K; Sugimoto, T; Takeda, K; Tatsumi, E | 1 |
| Dokhelar, MC; Fradelizi, D; Harel, A; Tursz, T; Wakasugi, H | 1 |
| Durham, JP; Fontana, JA; Ruppert, M | 1 |
| Abrams, SI; Brahmi, Z; Bray, RA | 1 |
| Liu, CK; Qian, GX; Rosen, A; Schmied, R; Schreiber, C; Waxman, S | 1 |
| Griffin, J; Kufe, DW; Mitchell, T; Shafman, T | 1 |
| Aimi, N; Endo, Y; Fujiki, H; Hakii, H; Hitotsuyanagi, Y; Horiuchi, T; Nakayasu, M; Sakai, S; Shudo, K; Suganuma, M | 1 |
| Palù, G | 1 |
| Ferrero, D; Pagliardi, GL; Pessano, S; Rovera, G | 1 |
| Fujita, Y; Honma, Y; Hozumi, M; Kasukabe, T; Nomura, H; Sakurai, M; Sampi, K; Tsushima, S | 1 |
| Blaese, RM; Decker, JM; Hall, RE; Muchmore, AV | 1 |
| Decal, DL; Whittington, KB; Zucker, RM | 1 |
| Price, BJ; Whittington, K; Zucker, RM | 1 |
| Anderson, NL; Callaham, MF; Gemmell, MA; Huberman, E; Murao, S | 1 |
| Cooper, HL; Feuerstein, N | 4 |
| Kitagawa, S; Miura, Y; Ohta, M; Saito, M; Sakamoto, S; Suda, K; Takaku, F | 1 |
| Fibach, E; Kornberg, A; Rachmilewitz, EA; Treves, A | 1 |
| Ferrero, D; Gallo, E; Lanfrancone, L; Tarella, C | 1 |
| Cabot, MC; Lackey, RJ | 1 |
| Ralph, P | 1 |
| Kitagawa, S; Miura, Y; Ohta, M; Saito, M; Takaku, F | 2 |
| Au, WW; Callaham, MF; Huberman, E; Workman, ML | 1 |
| Abe, E; Miyaura, C; Shiina, Y; Suda, T; Tanaka, H | 1 |
| Mannickarottu, V; Toub, DB; Yachnin, S | 1 |
| Luikart, SD; Maniglia, CA; Sartorelli, AC | 1 |
| AbdAllah, NA; Fisch, H; Flick, DA; Gifford, GE | 1 |
| Okabe, N; Saito, H; Suzuki, R; Yamada, K | 1 |
| Cabot, MC | 1 |
| Kato, R; Mita, S; Nakaki, T; Yamamoto, S | 1 |
| Brown, GE; Fischkoff, SA; Ordonez, JV | 1 |
| Anderson, WB; Cooper, HL; Feuerstein, N; Sahai, A; Salomon, DS | 1 |
| Abbott, RE; Callaham, MF; Fisher, PB; Huberman, E; Schachter, D | 1 |
| Misukonis, MA; Weinberg, JB | 1 |
| Blair, OC; Burger, DE; Jenis, DM; Sartorelli, AC; Stepanowski, AL | 1 |
| Endo, Y; Fujiki, H; Nakayasu, M; Shudo, K; Suganuma, M; Sugimura, T; Tahira, T | 1 |
| Bonner, WM; Pantazis, P | 1 |
| Iijima, S; Koike, K; Minami, S; Namikawa, R; Nishida, K; Ogata, S; Ota, K; Suchi, T; Takahashi, T; Tsuge, I; Ueda, R | 1 |
| Acs, G; Calderon, T; Christman, JK; Mendelsohn, N | 1 |
| Litcofsky, PB; Moore, MA; Ralph, P; Williams, N | 1 |
| Braslawsky, GR; Callaham, M; Fugiki, H; Huberman, E | 1 |
| Hoffman, DR; Huberman, E | 1 |
| Abrahm, J; Cooper, RA; Lange, B; Levis, A; Meo, P; Pegoraro, L; Rovera, G | 1 |
| Acs, G; Christman, JK; Gilbert, HS; Mendelsohn, N | 1 |
| Cooper, RA; Ip, SH | 1 |
| Greenberger, JS; Newburger, PE; Sakakeeny, M | 1 |
| Ghezzo, F; Palumbo, A; Pegoraro, L | 1 |
| Chang, LJ; McCulloch, EA | 1 |
| Fibach, E; Rachmilewitz, EA | 1 |
| Callaham, M; Herrmann, A; Huberman, E; Slaga, T; Weeks, C | 1 |
| Callaham, M; Huberman, E; Slaga, TJ; Solanki, V | 1 |
| Cassileth, PA; Cooper, RA; Suholet, D | 1 |
| Colbert, DA; Deisseroth, AB; Fontana, JA | 1 |
| Ip, SH; Lebman, D; Perussia, B; Rovera, G; Trinchieri, G | 1 |
| Lazarou, SA; Pantazis, P; Papadopoulos, NM | 1 |
| Abe, E; Konno, K; Kuribayashi, T; Miyaura, C; Nishii, Y; Suda, T; Tanaka, H | 1 |
| Bussolino, F; Camussi, G; Ghezzo, F; Pegoraro, L | 1 |
| Cooper, RA; Cossu, G; Kuo, AL; Pessano, S; Warren, L | 1 |
| Abrams, T; Griffin, JD; Nadler, LM; Ritz, J; Schlossman, SF; Todd, RF | 1 |
| Baylin, SB; Civin, CI; Luk, GD; Weissman, RM | 1 |
| Callaham, M; Huberman, E; Slaga, T; Solanki, V; Weeks, C | 1 |
| Honma, Y; Hozumi, M; Kasukabe, T | 1 |
| Dahlgren, C; Hed, J; Stendahl, O | 1 |
| Bloch, A; Minowada, J; Takeda, K | 1 |
| Brown, G; Bunce, CM; Michell, RH; Stone, PC; Toksoz, D | 1 |
| Galili, U; Gamliel, H; Gurfel, D; Korkesh, A; Leizerowitz, R; Polliack, A | 1 |
| Fibach, E; Kornberg, A; Peled, T; Rachmilewitz, EA; Treves, A | 1 |
| Abraham, S; Bottero, L; Ferrero, D; Lebman, D; Pagliardi, GL; Pessano, S; Rovera, G; Vartikar, J | 1 |
| Brossa, C; D'Alberto, M; Ghezzo, F; Palumbo, A; Pegoraro, L; Turco, GL | 1 |
| Sachs, L; Symonds, G | 1 |
| Bailly, JD; Bordier, C; Cassar, G; Duchayne, E; Jaffrézou, JP; Laurent, G; Pourquier, P | 1 |
| Austin, ED; Austin, GE; Findley, HW; Murtagh, JJ; Zhang, W; Zhao, WG | 1 |
| Srivastava, A; Srivastava, BI; Srivastava, MD | 1 |
| Brezinová, J; Hrabánek, J; Jelínek, J; Jirásek, A; Koubek, K; Lemez, P; Malasková, V; Michalová, K; Rypácková, B; Schwarz, J | 1 |
| Curnutte, JT; Grinstein, S; Nanda, A; Qu, AY | 1 |
| Hirano, T; Kitajima, K; Oda, T; Shimizu, N; Utiyama, H | 1 |
| Haimov, I; Kimchi, A; Levy, N; Melamed, D; Pfarr, CM; Resnitzky, D; Yaniv, M | 1 |
| Craig, RW; Guggino, WB; Lu, L; Markakis, D; Yang, T | 1 |
| Herwig, S; Ma, Y; Su, Q; Tempst, P; Zhang, W | 1 |
| Drexler, HG; Hu, ZB; Ma, W; MacLeod, R; Quentmeier, H; Zaborski, M | 1 |
| Freĭdlin, IS; Lasunskaia, EB; Machiulaĭtene, ER; Perekalina, TA | 1 |
| Asano, Y; Eto, T; Niho, Y; Ogo, T; Okamura, S; Otsuka, T | 1 |
| Hirokawa, M; Kitabayashi, A; Miura, AB; Mori, S; Moriyama, M; Onizuka, T; Yamochi, T | 1 |
| Dai, W; Gong, B; Lu, L; Wang, Y | 1 |
| Craig, RW; Eastman, A; Townsend, KJ; Traupman, MA; Trusty, JL | 1 |
| Ohnishi, K; Ohno, R; Sinjo, K; Takeshita, A; Tobita, T | 1 |
| Dai, W; Lu, L; Wang, L; Xu, D | 1 |
| Avraham, H; Jiang, S; London, R; Schinkmann, K; Taniguchi, Y | 1 |
| Li, T; Lu, L; Reinach, PS | 1 |
| Dodge, JE; List, AF; Munson, C | 1 |
| Caligiuri, MA; Der, CJ; Lambert, QT; Quilliam, LA; Rebhun, JF; Reuther, GW | 1 |
| Dai, W; Li, T; Lu, L | 1 |
| Diamond, L; O'Brien, TG; Rovera, G | 1 |
| Ganser, A; Herrmann, F; Lübbert, M; Ludwig, WD; Mertelsmann, R; Oster, W | 1 |
| Irino, S; Norman, AW; Tanaka, T; Taoka, T; Tasaka, T | 1 |
| Datta, R; Kharbanda, S; Kufe, D; Nakamura, T; Sherman, ML | 1 |
| Inoue, H; Kataoka, T; Kato, Y; Morishima, Y; Morishita, Y; Ogura, M; Saito, H; Towatari, M | 1 |
| Kimchi, A; Tiefenbrun, N | 1 |
| Chuang, LF; Chuang, RY | 1 |
| Esselink, MT; Halie, MR; van Zanten, AK; Vellenga, E; Wagteveld, AJ | 1 |
| Collart, FR; Huberman, E | 1 |
| Bloch, A; Denstman, SC; Guan, XP; Hromchak, RA; Takuma, T | 1 |
| Cannistra, SA; DiCarlo, J; Griffin, JD; Groshek, P; Koenigsmann, M | 1 |
| Abboud, CN; Lichtman, MA; Packman, CH; Sham, RL | 1 |
| Buchan, HL; Craig, RW; Kozopas, KM | 1 |
| Bloch, A; Fujii, Y; Takuma, T | 1 |
| Hidaka, H; Komada, F; Nishikawa, M; Shirakawa, S; Uemura, Y | 1 |
| Gee, CE; Griffin, J; Miller, LJ; Piwnica-Worms, H; Roberts, TM; Sastre, L; Springer, TA | 1 |
| Hall, RE; Leftwich, JA | 1 |
| Horiguchi, J; Kufe, D; Wakamiya, N | 1 |
| Ernst, TJ; Griffin, JD; O'Rourke, R; Ritchie, AR | 1 |
| Bertani, A; Colotta, F; Mantovani, A; Polentarutti, N; Rambaldi, A; Sica, A | 1 |
| Afanas'ev, BV; Balaian, LN; Ostrovskiĭ, AM; Prianishnikov, VA | 1 |
| Chen, ZX; Wang, W; Wu, WL | 1 |
| Grosso, LE; Pitot, HC | 2 |
| Bloch, A; Guan, XP; Hromchak, RA | 1 |
| Abraham, RT; Ashendel, CL; Hooper, WC; Woloschak, GE | 1 |
| Knauf, PA; Kozody, DJ; Restrepo, D | 1 |
| Fishbaugh, J; Freeman, L; Yen, A | 1 |
| Deli, E; Kiss, Z; Kuo, JF | 3 |
| Sagoh, T; Yamada, M | 1 |
| Caon, AC; Faucher, N; McColl, SR; Naccache, PH | 1 |
| Cayre, YE; Raynal, MC; Solomon, DH; Tejwani, GA | 1 |
| Haddox, MK; Maddox, AM | 1 |
| Al-Katib, A; Koziner, B; Stavnezer, J | 1 |
| Beatty, PG; Fisher, W; Harlan, JM; Hickstein, DD; Locksley, RM; Root, RK; Schwartz, BR; Smith, A | 1 |
| Ina, Y; Koide, Y; Nezu, N; Yoshida, TO | 2 |
| Caldwell, AB; Kreutter, D; Morin, MJ | 1 |
| Hoffbrand, AV; Katz, F; Michalevicz, R; Taheri, MR | 1 |
| Cuatrecasas, P; Jacobs, S; May, WS; Sahyoun, N; Wolf, M | 1 |
| Borelli, TJ; Konno, S; Quaini, F; Vuolo, LL; Wu, JM | 1 |
| Andoh, T; Gatanaga, T; Kitahara, N; Morioka, H; Murata, M; Shibai, H; Soma, G | 1 |
| Andersson, T; Dahlgren, C; Magnusson, KE; Stendahl, O | 1 |
| Ballestrero, A; Dallegri, F; Frumento, G; Patrone, F | 1 |
| Connolly, NL; Senior, RM; Welgus, HG | 1 |
| Müller, R | 1 |
| Barnekow, A; Gessler, M | 1 |
| Filli, S; Ioannides, CG; Papamichail, M; Petraki, H | 1 |
| Furman, WL; Holt, JT; Nienhuis, AW; Rettenmier, CW; Roussel, MF; Sacca, R; Sherr, CJ; Stanley, ER | 1 |
| Carpentier, JL; Gorden, P; Iacopetta, B; Lew, DP; Orci, L; Pozzan, T | 1 |
| Kasugai, I; Yamada, M | 1 |
| Koeffler, HP; Norman, AW; Reichel, H | 1 |
| Mazzone, A; Ricevuti, G; Rizzo, SC; Sacchi, S | 1 |
| Carchman, RA; Gaut, JR | 1 |
| Mochizuki, T; Okazaki, T; Sawada, H; Tashima, M; Uchino, H | 2 |
| Chubb, CB; Gemmell, MA; Huberman, E; Maeda, S; Murison, G | 1 |
| Akard, LP; Gabig, TG; Parkinson, JF; Schell, MJ | 1 |
| Deli, E; Girard, PR; Kiss, Z; Kuo, JF; Pettit, GR | 1 |
| Andersson, T; Dahlgren, C; Stendahl, O | 1 |
| Fox, RM; Mann, GJ; Musgrove, EA; Thelander, L | 1 |
| Booker, L; Browman, GP; Damji, N; Khoo, KE | 1 |
| Henning-Chubb, C; Huberman, E; Mitchell, RL; Verma, IM | 1 |
| Hattori, T; Ishii, T; Kawano, F; Matsuoka, M; Takatsuki, K; Uchiyama, T | 1 |
| Wong, T; Wu, MC; Yunis, AA; Ziboh, VA | 1 |
| Glazer, RI; Knode, MC; Zylber-Katz, E | 1 |
| Colotta, F; Mantovani, A; Polentarutti, N; Wang, JM | 1 |
| Endo, Y; Fujiki, H; Hasegawa, M; Hirota, M; Horiuchi, T; Nakayasu, M; Shudo, K; Suganuma, M; Yoshizawa, S | 1 |
| Kreutter, D; Morin, MJ; Rasmussen, H; Sartorelli, AC | 1 |
| Amadori, S; Bottero, L; Mandelli, F; Mastroberardino, G; Mavilio, F; Pelosi, E; Peschle, C; Petrini, M; Sposi, NM; Testa, U | 1 |
| Fujiki, H; Hirota, M; Nakayasu, M; Ojika, M; Suganuma, M; Sugimura, T; Suguri, H; Wakamatsu, K; Yamada, K; Yoshizawa, S | 1 |
| Hickman, J; Hughes, L; Thompson, M | 1 |
| Aquino, A; Glazer, RI; Grant, S; Hartman, KD; Huang, KP; Knode, MC; Niu, CH | 1 |
| Cooper, HL; Feuerstein, N; Nishikawa, M | 1 |
| Glazer, RI; Zylber-Katz, E | 2 |
| Kato, Y; Okazaki, T; Sawada, H; Tashima, M; Uchino, H | 1 |
| Malvoisin, E; Wild, F; Zwingelstein, G | 2 |
| Gailani, D; Macfarlane, DE; Vann, K | 1 |
| Gemmell, MA; Homma, Y; Huberman, E | 1 |
| Arai, K; Kondo, A; Matsumoto, M; Taki, T | 1 |
| Basset, M; Cockcroft, S; Cost, H; Geny, B; LePeuch, C | 1 |
| Baxter, CS; DeBord, DG | 1 |
| Kufe, D; Sariban, E | 1 |
| Banerjee, D; McFarlane, DL; Zanyk, MJ | 1 |
| Chen, SS; Tang, JQ | 1 |
| Coustan-Smith, E; Drexler, HG; Gignac, SM; Hoffbrand, AV; Jani, H | 1 |
| Berkvens, TM; Khan, PM; Schoute, F; van der Eb, AJ; van Ormondt, H | 1 |
| Baker, VV; Kraft, AS; May, WS | 1 |
| Niedel, JE; Salehi, Z; Taylor, JD | 1 |
| Sugihara, H; Yun, K | 1 |
| Macfarlane, DE | 1 |
| Kuo, JF; Mazzei, GJ; Shoji, M; Su, HD; Vogler, WR | 1 |
| Afford, SC; Brown, G; Bunce, CM; Burnett, D; Crocker, J; Stockley, RA | 1 |
| Luikart, SD | 1 |
| Akagi, T; Kubonishi, I; Miyagi, T; Miyoshi, I; Ohtsuki, Y; Yoshimoto, S | 1 |
| Center, MS; Marsh, W | 1 |
| Cohen, A; Estrov, Z; Freedman, MH; Kaplinsky, C | 1 |
| Bell, RM; Hannun, YA; Kinkade, JM; Merrill, AH; Sereni, AM; Stevens, VL | 1 |
| Hidaka, H; Nishikawa, M; Shirakawa, S; Uemura, Y | 1 |
| Bhattacharya, B; Braverman, R; Cooper, HL; Feuerstein, N | 1 |
| Kasuya, J; Momoi, T; Senoo, H; Shinmoto, M; Suzuki, Y | 1 |
| Deli, E; Kiss, Z; Koeffler, HP; Kuo, JF; Pettit, GR; Shoji, M; Vogler, WR | 1 |
| Breitman, TR; Imaizumi, M; Uozumi, J | 1 |
| Ikeda, K; Kikuchi, A; Kozawa, O; Takai, Y | 1 |
| Ferro, AJ; Fitchen, JH; Olson, KD; Riscoe, MK; Schwamborn, J | 1 |
| Hara, A; Ito, K; Shibata, H; Shichijo, S; Shiotsuki, K; Shiraishi, M; Tsunosue, R; Yokoyama, MM | 1 |
| Chini, L; Fattorossi, A; Galli, E; Gidlund, M; Jondal, M; Laan, K; Rossi, P; Wigzell, H | 1 |
| Dale, IL; Gescher, A; Lazenby, CM | 1 |
| Luikart, SD; Maniglia, CA; Sackrison, JL | 1 |
| Charp, PA; Girard, PR; Koeffler, HP; Kuo, JF; Shoji, M; Vogler, WR | 1 |
| Gazitt, Y; Gurfel, D; Leizerowitz, R; Or, R; Polliack, A | 1 |
| Rhyner, K; Taetle, R | 1 |
| Drexler, HG; Gaedicke, G; Hoffbrand, AV; Minowada, J | 1 |
| Abrahm, JL; Cassileth, PA; Cooper, RA; Gerson, SL; Hoxie, JA; Tannenbaum, SH | 1 |
| Antoniades, HN; Kufe, D; Pantazis, P; Sariban, E | 1 |
| Chen, TA; Chou, KL; Chou, RH; Churchill, JR; Thompson, SW | 1 |
| Calabretta, B | 1 |
| Fukuda, M; Siebert, PD | 1 |
| Kufe, D; Mitchell, T; Sariban, E; Watanabe, T | 1 |
| Bar-Tana, R; Barak, V; Fibach, E; Gamliel, H; Halimi, M; Halperin, M; Leizerowitz, R; Polliack, A; Treves, AJ | 1 |
| Brader, K; Miller, DM; Polansky, DA; Yang, A | 1 |
| Bhalla, K; Fisher, PB; Grant, S; Mileno, MD; Pestka, S; Weinstein, B | 1 |
| Anderson, NL; Coussens, PM; Gemmell, MA; Huberman, E; Murao, S | 1 |
| Bilello, PA; Chang, CS; Ferrari, AC; Gallagher, RE; Muly, EC; Nickols, WA; Yen, RW | 1 |
| Bowers, CH; Den, T; Svet-Moldavsky, IA; Wroblesky, H | 1 |
| Lemez, P | 1 |
| Clarkson, B; Gulati, SC; Svet-Moldavsky, I | 1 |
| Andersson, T; Krause, KH; Lew, PD; Schlegel, W; Waldvogel, FA; Wollheim, CB | 1 |
| Mitchell, RL; Schreiber, RD; Verma, IM; Zokas, L | 1 |
| David, JR; Liu, DY; Remold, HG; Yu, SF | 1 |
| Cooper, HL; Feuerstein, N; Monos, DS | 1 |
| Ross, DW | 1 |
| Kasuga, M; Takaku, F; Tsushima, T; Yamanouchi, T | 1 |
| Bravo, R; Curran, T; Müller, R | 1 |
5 review(s) available for tetradecanoylphorbol acetate and Acute Myelogenous Leukemia
| Article | Year |
|---|---|
Cytometry of intracellular signaling: from laboratory bench to clinical application.
Topics: Antibodies, Phospho-Specific; Fixatives; Flow Cytometry; Fluorescent Dyes; Humans; Image Cytometry; Intercellular Signaling Peptides and Proteins; Intracellular Signaling Peptides and Proteins; Leukemia, Myeloid, Acute; Lipopolysaccharides; Metabolic Networks and Pathways; Methanol; Phosphoproteins; Phosphorylation; Protein Kinase Inhibitors; Signal Transduction; Staining and Labeling; Tetradecanoylphorbol Acetate; Tissue Fixation | 2011 |
[Effect of tumor promotor on neoplastic cell transformation].
Topics: Animals; Carcinogens; Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; Guinea Pigs; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Macrophages; Mice; Phorbols; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1983 |
Cellular and viral fos genes: structure, regulation of expression and biological properties of their encoded products.
Topics: Amino Acid Sequence; Animals; Base Sequence; Bone Neoplasms; Cell Differentiation; Cell Division; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Cell Transformation, Viral; Fibroblasts; Gene Expression Regulation; Gene Products, gag; Hematopoiesis; Humans; Leukemia, Myeloid, Acute; Male; Mice; Oncogenes; Osteosarcoma; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogenes; Rats; Retroviridae Proteins; Sarcoma Viruses, Murine; Teratoma; Tetradecanoylphorbol Acetate | 1986 |
Leukemic cell maturation.
Topics: Cell Differentiation; Cell Line; Chromosome Aberrations; Chromosome Disorders; Cytarabine; Dimethyl Sulfoxide; Genotype; Hematopoietic Stem Cells; Humans; Leukemia; Leukemia, Myeloid, Acute; Neoplastic Stem Cells; Neutrophils; Oncogenes; Phenotype; Tetradecanoylphorbol Acetate; Vitamin A | 1985 |
Transient induction of c-fos and c-myc in an immediate consequence of growth factor stimulation.
Topics: Animals; Blood; Calcimycin; Cell Line; Cell Transformation, Neoplastic; Colony-Stimulating Factors; Gene Expression Regulation; Growth Substances; Humans; Leukemia, Myeloid, Acute; Macrophages; Proto-Oncogenes; RNA, Messenger; Tetradecanoylphorbol Acetate | 1985 |
1 trial(s) available for tetradecanoylphorbol acetate and Acute Myelogenous Leukemia
| Article | Year |
|---|---|
Pharmacodynamic monitoring of BAY 43-9006 (Sorafenib) in phase I clinical trials involving solid tumor and AML/MDS patients, using flow cytometry to monitor activation of the ERK pathway in peripheral blood cells.
Topics: Aged; Aged, 80 and over; Antigens, CD; Antigens, CD34; Antigens, Differentiation, Myelomonocytic; Benzenesulfonates; CD13 Antigens; CD3 Complex; Drug Monitoring; Extracellular Signal-Regulated MAP Kinases; Flow Cytometry; Hemolysis; Humans; Leukemia, Myeloid, Acute; Leukocytes, Mononuclear; MAP Kinase Signaling System; Middle Aged; Models, Biological; Myelodysplastic Syndromes; Neoplasms; Niacinamide; Phenylurea Compounds; Phosphorylation; Pyridines; Sialic Acid Binding Ig-like Lectin 3; Sorafenib; Stem Cell Factor; Stem Cells; Tetradecanoylphorbol Acetate | 2006 |
277 other study(ies) available for tetradecanoylphorbol acetate and Acute Myelogenous Leukemia
| Article | Year |
|---|---|
ZBTB7A prevents RUNX1-RUNX1T1-dependent clonal expansion of human hematopoietic stem and progenitor cells.
Topics: Animals; Bone Marrow; Carcinogenesis; Cell Cycle Checkpoints; Cell Differentiation; Cell Line, Tumor; Cell Lineage; Core Binding Factor Alpha 2 Subunit; Deoxyglucose; DNA-Binding Proteins; Gene Knockout Techniques; Glycolysis; Hematopoiesis; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid, Acute; Loss of Function Mutation; Mice; Myeloid Progenitor Cells; Oncogene Proteins, Fusion; RUNX1 Translocation Partner 1 Protein; Tetradecanoylphorbol Acetate; Transcription Factors; Xenograft Model Antitumor Assays | 2020 |
PLSCR1/IP3R1/Ca
Topics: Active Transport, Cell Nucleus; Animals; Calcium; Calcium Signaling; Cell Differentiation; Cell Nucleus; Female; Flavanones; Glucosides; Humans; Inositol 1,4,5-Trisphosphate Receptors; Leukemia, Myeloid, Acute; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Proteins; Phospholipid Transfer Proteins; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 2017 |
Reactive oxygen species activate differentiation gene transcription of acute myeloid leukemia cells via the JNK/c-JUN signaling pathway.
Topics: Acetylcysteine; Cell Differentiation; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Humans; JNK Mitogen-Activated Protein Kinases; Leukemia, Myeloid, Acute; MAP Kinase Signaling System; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-jun; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Transcription, Genetic | 2018 |
Adult patients with
Topics: Adult; Aged; Antimycin A; Antioxidants; Female; Humans; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Lipid Peroxidation; Male; Middle Aged; Mitochondria; NADPH Oxidases; Onium Compounds; Oxidation-Reduction; Prognosis; Proportional Hazards Models; Prospective Studies; Reactive Oxygen Species; Rotenone; Tetradecanoylphorbol Acetate; Translocation, Genetic | 2019 |
MiR-181 family: regulators of myeloid differentiation and acute myeloid leukemia as well as potential therapeutic targets.
Topics: Animals; Base Sequence; Calcium-Calmodulin-Dependent Protein Kinase Kinase; Cattle; CCAAT-Enhancer-Binding Proteins; Cell Differentiation; Gene Expression Regulation, Neoplastic; Granulocytes; Hematopoietic Stem Cells; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Macrophages; Mice; MicroRNAs; Molecular Targeted Therapy; Myeloid Cells; Protein Kinase C-delta; Rats; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Transduction, Genetic; Tretinoin; Tumor Suppressor Proteins | 2015 |
miR-638 regulates differentiation and proliferation in leukemic cells by targeting cyclin-dependent kinase 2.
Topics: Base Sequence; Biomarkers, Tumor; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase 2; Gene Expression Regulation, Leukemic; HEK293 Cells; Hematopoiesis; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; MicroRNAs; Molecular Sequence Data; Oligonucleotides; Phenotype; Sequence Homology, Nucleic Acid; Tetradecanoylphorbol Acetate; Up-Regulation | 2015 |
Suppression of APC/CCdh1 has subtype specific biological effects in acute myeloid leukemia.
Topics: Adult; Aged; Aged, 80 and over; Antigens, CD; Cadherins; Cell Cycle Checkpoints; Cell Differentiation; Female; Gene Knockdown Techniques; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Tetradecanoylphorbol Acetate; Tretinoin; Young Adult | 2016 |
The human nucleophosmin 1 mutation A inhibits myeloid differentiation of leukemia cells by modulating miR-10b.
Topics: Adult; Aged; Cell Differentiation; Female; HL-60 Cells; Humans; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Leukemia, Myeloid, Acute; Male; MicroRNAs; Middle Aged; Mutation; Nuclear Proteins; Nucleophosmin; Tetradecanoylphorbol Acetate | 2016 |
miR-320 targets transferrin receptor 1 (CD71) and inhibits cell proliferation.
Topics: Antigens, CD; Carcinogens; Cell Differentiation; Cell Proliferation; Down-Regulation; Gene Expression Regulation, Leukemic; Hematopoiesis; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; MicroRNAs; Receptors, Transferrin; Tetradecanoylphorbol Acetate | 2009 |
Synergistic induction of gene expression during the differentiation into mature macrophage in human myeloblastic leukemia cells treated with TPA and KH1060.
Topics: Base Sequence; Blotting, Northern; Calcitriol; Cell Differentiation; Cell Line, Tumor; DNA Primers; Gene Expression Regulation; Humans; Leukemia, Myeloid, Acute; Macrophages; Tetradecanoylphorbol Acetate | 2009 |
The downregulation of onzin expression by PKCepsilon-ERK2 signaling and its potential role in AML cell differentiation.
Topics: Cell Differentiation; Cell Line, Tumor; Down-Regulation; Humans; Leukemia, Myeloid, Acute; Mitogen-Activated Protein Kinase 1; Oncogene Proteins; Protein Kinase C-epsilon; Proteins; Proto-Oncogene Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Trans-Activators; Tretinoin | 2010 |
Expression of heme oxygenase-1 in human leukemic cells and its regulation by transcriptional repressor Bach1.
Topics: Basic-Leucine Zipper Transcription Factors; Cell Line, Tumor; Cell Survival; Fanconi Anemia Complementation Group Proteins; Gene Expression Regulation; Heme Oxygenase-1; Humans; Leukemia, Myeloid, Acute; Lipopolysaccharides; Monocytes; NF-E2-Related Factor 2; Repressor Proteins; Tetradecanoylphorbol Acetate | 2010 |
Expression of β1,3-N-acetylglucosaminyltransferases during differentiation of human acute myeloid leukemia cells.
Topics: Cell Differentiation; Cell Line, Tumor; Dimethyl Sulfoxide; Flow Cytometry; Fluorescence; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Leukemic; Humans; Leukemia, Myeloid, Acute; N-Acetylglucosaminyltransferases; Polysaccharides; Tetradecanoylphorbol Acetate; Tretinoin; Up-Regulation | 2011 |
MicroRNA-29a and microRNA-142-3p are regulators of myeloid differentiation and acute myeloid leukemia.
Topics: Antineoplastic Agents; Carcinogens; Cell Differentiation; Cell Line, Tumor; Cell Transformation, Neoplastic; Gene Expression Regulation, Leukemic; HEK293 Cells; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; MicroRNAs; Myeloid Cells; Tetradecanoylphorbol Acetate; Transfection; Tretinoin | 2012 |
Monoclonal antibodies against receptor-induced binding sites detect cell-bound plasminogen in blood.
Topics: Antibodies, Monoclonal; Antibody Specificity; Binding Sites; Carcinogens; Erythrocytes; Flow Cytometry; Humans; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Lipopolysaccharides; Lymphocytes; Monocytes; Neutrophils; Plasminogen; Radioligand Assay; Tetradecanoylphorbol Acetate | 2012 |
Erythroid differentiation-associated gene interacts with NPM1 (nucleophosmin/B23) and increases its protein stability, resisting cell apoptosis.
Topics: Apoptosis; Benzamides; Cycloheximide; Down-Regulation; Gene Knockdown Techniques; HEK293 Cells; Humans; Imatinib Mesylate; Immunoprecipitation; K562 Cells; Leukemia, Myeloid, Acute; Nuclear Proteins; Nucleophosmin; Piperazines; Pyrimidines; Tetradecanoylphorbol Acetate | 2012 |
Granulocyte maturation determines ability to release chromatin NETs and loss of DNA damage response; these properties are absent in immature AML granulocytes.
Topics: Blotting, Western; Cell Differentiation; Cell Proliferation; Cells, Cultured; Chromatin; Chromobox Protein Homolog 5; Chromosomal Proteins, Non-Histone; DNA Damage; Fluorescent Antibody Technique; Granulocytes; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid, Acute; Neutrophils; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetradecanoylphorbol Acetate | 2013 |
Involvement of diverse protein kinase C isoforms in the differentiation of ML-1 human myeloblastic leukemia cells induced by the vitamin D3 analogue KH1060 and the phorbol ester TPA.
Topics: Calcitriol; Cell Differentiation; Humans; Isoenzymes; Leukemia, Myeloid, Acute; Mitogen-Activated Protein Kinases; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-epsilon; Protein Kinase C-theta; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2002 |
Biomic study of human myeloid leukemia cells differentiation to macrophages using DNA array, proteomic, and bioinformatic analytical methods.
Topics: Cell Differentiation; Computational Biology; Electrophoresis, Gel, Two-Dimensional; Gene Expression Profiling; Genomics; HL-60 Cells; Humans; Image Processing, Computer-Assisted; Leukemia, Myeloid, Acute; Macrophages; Oligonucleotide Array Sequence Analysis; Proteomics; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tetradecanoylphorbol Acetate | 2002 |
A sensitive bioassay for measuring blood levels of 12-O-tetradecanoylphorbol-13-acetate (TPA) in patients: preliminary pharmacokinetic studies.
Topics: Biological Assay; Cell Adhesion; Drug Stability; Half-Life; HL-60 Cells; Humans; Infusions, Intravenous; Leukemia, Myeloid, Acute; Sensitivity and Specificity; Tetradecanoylphorbol Acetate | 2002 |
Superoxide radical generation and Mn- and Cu-Zn superoxide dismutases activities in human leukemic cells.
Topics: Adult; Anions; Child; Humans; Imidazoles; Leukemia; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Leukocytes; Manganese; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Oxidative Stress; Oxygen; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pyrazines; Sodium Dodecyl Sulfate; Superoxide Dismutase; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 2003 |
Terminal differentiation in vitro of patient-derived post-TMD megakaryoblastic AML cells.
Topics: Acute Disease; Cell Differentiation; Cells, Cultured; Child, Preschool; Flow Cytometry; Glycophorins; Humans; Leukemia, Myeloid, Acute; Megakaryocytes; Myeloproliferative Disorders; Phenotype; Platelet Membrane Glycoprotein IIb; Reverse Transcriptase Polymerase Chain Reaction; Tetradecanoylphorbol Acetate | 2003 |
Constitutive cytoplasmic localization of p21(Waf1/Cip1) affects the apoptotic process in monocytic leukaemia.
Topics: Alkaloids; Apoptosis; Base Sequence; Benzophenanthridines; Blast Crisis; Bone Marrow Cells; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Enzyme Inhibitors; Granulocytes; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Monocytes; Oligonucleotide Probes; Phenanthridines; Reference Values; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; U937 Cells | 2003 |
Effect of phorbol esters on iron uptake in human hematopoietic cell lines.
Topics: Biological Transport; Calcifediol; Calcitriol; Cell Line; Dimethyl Sulfoxide; Heme; Humans; Iron; Iron Radioisotopes; Kinetics; Leukemia, Myeloid, Acute; Phorbol Esters; Phorbols; Receptors, Cell Surface; Receptors, Transferrin; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Transferrin; Tretinoin | 1984 |
Alternative myelomonocytic differentiation of HL-60 reflects dual prospective potency of promyelocytes in human.
Topics: Antibodies, Monoclonal; Cell Differentiation; Cell Line; Concanavalin A; Dimethyl Sulfoxide; Esterases; Granulocytes; Humans; Immunoenzyme Techniques; Leukemia, Myeloid, Acute; Lymphocytes; Lymphokines; Monocytes; Peroxidase; Phenotype; Tetradecanoylphorbol Acetate; Tretinoin | 1984 |
Effect of 5-azacytidine on differentiation and DNA methylation in human promyelocytic leukemia cells (HL-60).
Topics: Azacitidine; Cell Differentiation; Cell Line; Clone Cells; DNA (Cytosine-5-)-Methyltransferases; DNA, Neoplasm; Humans; Leukemia, Myeloid, Acute; Methylation; Methyltransferases; Superoxides; Tetradecanoylphorbol Acetate | 1983 |
Secretion of plasminogen activators by human myeloid leukemic cells: modulation and therapeutic correlations.
Topics: Cells, Cultured; Dexamethasone; Humans; Leukemia, Myeloid, Acute; Leukocytes; Palliative Care; Plasminogen Activators; Reference Values; Tetradecanoylphorbol Acetate | 1983 |
Lateral diffusion of wheat germ agglutinin-labeled glycoconjugates in the membrane of differentiating HL-60 and U-937 cells assessed with fluorescence recovery after photobleaching (FRAP).
Topics: Cell Differentiation; Cell Line; Cell Membrane; Dimethyl Sulfoxide; Fluorescence; Humans; Lectins; Leukemia, Myeloid, Acute; Phagocytosis; Tetradecanoylphorbol Acetate; Wheat Germ Agglutinins | 1983 |
Early decline in c-myb oncogene expression in the differentiation of human myeloblastic leukemia (ML-1) cells induced with 12-O-tetradecanoylphorbol-13-acetate.
Topics: Cell Differentiation; Cell Division; DNA Replication; Electrophoresis, Agar Gel; Gene Expression Regulation; Humans; Leukemia, Myeloid, Acute; Nucleic Acid Hybridization; Oncogenes; Phorbols; RNA; Tetradecanoylphorbol Acetate; Time Factors | 1984 |
Differentiation of human T-lymphoid leukemia cells into cells that have a suppressor phenotype is induced by phorbol 12-myristate 13-acetate.
Topics: Antibodies, Monoclonal; Antigens, Surface; Cell Differentiation; Cell Line; Humans; Leukemia, Myeloid, Acute; Phorbols; T-Lymphocytes, Regulatory; Tetradecanoylphorbol Acetate | 1982 |
Plasminogen activator activity in differentiating leukemia cells.
Topics: Cell Adhesion; Cell Differentiation; Cell Line; Dexamethasone; Fibrinolysin; Humans; Leukemia, Myeloid, Acute; Plasminogen; Plasminogen Activators; Tetradecanoylphorbol Acetate | 1984 |
Phorbol diester-induced macrophage differentiation of leukemic blasts from patients with human myelogenous leukemia.
Topics: Cell Adhesion; Cell Differentiation; Histocytochemistry; Humans; Leukemia, Myeloid, Acute; Macrophages; Muramidase; Naphthol AS D Esterase; Nitroblue Tetrazolium; Peroxidase; Phagocytosis; Phorbols; Sodium Fluoride; Tetradecanoylphorbol Acetate | 1980 |
Functionally deficient differentiation of HL-60 promyelocytic leukemia cells induced by phorbol myristate acetate.
Topics: Cell Differentiation; Complement System Proteins; Humans; Leukemia, Myeloid, Acute; Macrophages; Nucleotidases; Oxygen Consumption; Phagocytosis; Phorbols; Tetradecanoylphorbol Acetate | 1981 |
Induction of differentiation in human promyelocytic leukemia cells by tumor promoters.
Topics: Cell Adhesion; Cell Line; Cells, Cultured; Dimethyl Sulfoxide; Diterpenes; Humans; Leukemia, Myeloid, Acute; Muramidase; Peroxidase; Phagocytosis; Phorbol Esters; Tetradecanoylphorbol Acetate | 1982 |
Induction of cytoskeleton-associated proteins during differentiation of human myeloid leukemic cell lines.
Topics: Carcinoma, Small Cell; Cell Differentiation; Cell Line; Fluorescent Antibody Technique; Humans; Intermediate Filament Proteins; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lung Neoplasms; Neoplasm Proteins; Tetradecanoylphorbol Acetate; Vimentin | 1982 |
The role of phorbol ester receptor binding in responses to promoters by mouse and human cells.
Topics: Animals; Caenorhabditis elegans Proteins; Carcinogens; Carrier Proteins; Cell Differentiation; Cell Line; Clone Cells; Drug Resistance; Humans; Leukemia, Myeloid, Acute; Mice; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Kinase C; Receptors, Cell Surface; Receptors, Drug; Skin; Tetradecanoylphorbol Acetate | 1983 |
Specific receptors for phorbol diesters on freshly isolated human myeloid and lymphoid leukemia cells: comparable binding characteristics despite different cellular responses.
Topics: Binding Sites; Caenorhabditis elegans Proteins; Carrier Proteins; Cell Adhesion; Culture Media; Granulocytes; Humans; Leukemia, Hairy Cell; Leukemia, Myeloid, Acute; Lymphocytes; Protein Kinase C; Receptors, Cell Surface; Receptors, Drug; Tetradecanoylphorbol Acetate | 1984 |
Extracellular cytolysis by leukaemic blast cells.
Topics: Adult; Cytotoxicity Tests, Immunologic; Humans; Leukemia, Myeloid, Acute; Leukocytes; Superoxides; Tetradecanoylphorbol Acetate | 1984 |
Inhibition by palmitoylcarnitine of adhesion and morphological changes in HL-60 cells induced by 12-O-tetradecanoylphorbol-13-acetate.
Topics: Caenorhabditis elegans Proteins; Carnitine; Carrier Proteins; Cell Adhesion; Cell Line; Drug Antagonism; Humans; Kinetics; Leukemia, Myeloid, Acute; Palmitoylcarnitine; Phorbol Esters; Phorbols; Protein Kinase C; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1984 |
Evidence for cell cycle phase-specific initiation of a program of HL-60 cell myeloid differentiation mediated by inducer uptake.
Topics: Biological Transport; Cell Cycle; Cell Differentiation; Cell Line; DNA, Neoplasm; Flow Cytometry; Humans; Kinetics; Leukemia, Myeloid, Acute; Superoxides; Tetradecanoylphorbol Acetate; Tretinoin | 1984 |
Subcellular distribution of cyclic adenosine 3':5'-monophosphate-dependent protein kinase during the chemically induced differentiation of HL-60 cells.
Topics: Bucladesine; Carrier Proteins; Cell Differentiation; Cell Division; Cell Line; Cyclic AMP Receptor Protein; Dimethyl Sulfoxide; Humans; Kinetics; Leukemia, Myeloid, Acute; Protein Kinases; Subcellular Fractions; Tetradecanoylphorbol Acetate; Tretinoin | 1984 |
Rapid internalization of the transferrin receptor in K562 cells is triggered by ligand binding or treatment with a phorbol ester.
Topics: Biological Transport; Cell Line; Cell Membrane; Humans; Iron; Iron Radioisotopes; Kinetics; Leukemia, Myeloid, Acute; Phorbols; Receptors, Cell Surface; Receptors, Transferrin; Tetradecanoylphorbol Acetate; Transferrin | 1984 |
Phorbol esters rapidly stimulate amiloride-sensitive Na+/H+ exchange in a human leukemic cell line.
Topics: Amiloride; Carrier Proteins; Cell Line; Humans; Kinetics; Leukemia, Myeloid, Acute; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Pyrazines; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate | 1984 |
Gamma-interferon induces expression of the HLA-D antigens on normal and leukemic human myeloid cells.
Topics: B-Lymphocytes; Calcitriol; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Deltaretrovirus; Genes, MHC Class II; Histocompatibility Antigens Class II; Humans; Interferon Type I; Leukemia, Myeloid, Acute; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1984 |
Analysis of human promyelocytic leukemia cell (HL60) variants insensitive to phorbol ester tumor promoters.
Topics: Caenorhabditis elegans Proteins; Carcinogens; Carrier Proteins; Cell Line; Genetic Variation; Humans; Kinetics; Leukemia, Myeloid, Acute; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Kinase C; Receptors, Cell Surface; Receptors, Drug; Superoxide Dismutase; Tetradecanoylphorbol Acetate | 1984 |
Synthesis of cathepsin B by cells derived from the HL60 promyelocytic leukaemia cell line.
Topics: Cathepsin B; Cathepsins; Cell Differentiation; Cell Line; Dimethyl Sulfoxide; Granulocytes; Humans; Immunoenzyme Techniques; Leukemia, Myeloid, Acute; Macrophages; Palatine Tonsil; Tetradecanoylphorbol Acetate | 1983 |
Modulation of cell surface antigens induced by 12-O-tetradecanoyl-phorbol 13-acetate in two myeloblastic cell lines, a promyelocytic cell line, and a monoblastic cell line: detection with five monoclonal antibodies.
Topics: Antibodies, Monoclonal; Antigens, Surface; Cell Adhesion; Cell Line; Cell Membrane; Fluorescent Antibody Technique; Humans; Kinetics; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Macrophages; Monocytes; Phorbols; Tetradecanoylphorbol Acetate; Time Factors | 1984 |
Accessory function and interleukin 1 production by human leukemic cell lines.
Topics: Cell Line; Cell Transformation, Neoplastic; Histocompatibility Antigens Class II; HLA-DR Antigens; Humans; Interleukin-1; Isoelectric Focusing; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lymphocyte Activation; Lymphocyte Cooperation; Lymphoma, Large B-Cell, Diffuse; Monocytes; Phenotype; Phytohemagglutinins; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1984 |
Glycosyltransferase activities and the differentiation of human promyelocytic (HL60) cells by retinoic acid and a phorbol ester.
Topics: Cell Differentiation; Cell Line; Fucosyltransferases; Galactosyltransferases; Hexosyltransferases; Humans; Kinetics; Leukemia, Myeloid, Acute; Neuraminidase; Phorbols; Tetradecanoylphorbol Acetate; Tretinoin | 1983 |
Mechanism of action of phorbol myristate acetate on human natural killer cell activity.
Topics: Calcimycin; Cell Adhesion; Cell Line; Cytochalasins; Cytotoxicity, Immunologic; Humans; Killer Cells, Natural; Kinetics; Leukemia, Myeloid, Acute; Mycotoxins; Phorbols; Tetradecanoylphorbol Acetate | 1983 |
Glycosyltransferase alterations are cell type related when human promyelocytic leukemia (HL-60) cells are treated with various inducers of differentiation.
Topics: Cell Line; Cell Transformation, Neoplastic; Decarboxylation; Deoxyglucose; Dimethyl Sulfoxide; Fucosyltransferases; Galactosyltransferases; Hexosyltransferases; Humans; Leukemia, Myeloid, Acute; Sialyltransferases; Substrate Specificity; Tetradecanoylphorbol Acetate; Tretinoin | 1983 |
Polyamine requirements for induction of HL-60 promyelocyte differentiation by leukocyte-conditioned medium and phorbol ester.
Topics: Antibodies, Monoclonal; Cell Differentiation; Cell Line; Culture Media; Eflornithine; Humans; Kinetics; Leukemia, Myeloid, Acute; Leukocytes; Ornithine; Ornithine Decarboxylase Inhibitors; Phorbols; Polyamines; Spermidine; Tetradecanoylphorbol Acetate | 1984 |
Studies on olivoretins indicate a requirement for a free hydroxyl group for teleocidin B activity.
Topics: Animals; Caenorhabditis elegans Proteins; Carcinogens; Carrier Proteins; Cell Adhesion; Cell Line; Enzyme Induction; Humans; Leukemia, Myeloid, Acute; Lyngbya Toxins; Mice; Ornithine Decarboxylase; Protein Kinase C; Receptors, Drug; Receptors, Immunologic; Skin; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1984 |
[The effect of 12-O-tetradecanoylphorbol-13-acetate on acute myeloid leukemia cells obtained directly from the patient. Failure of the compound to induce a "true" maturation].
Topics: Cells, Cultured; Humans; Leukemia, Myeloid, Acute; Phorbols; Tetradecanoylphorbol Acetate | 1981 |
Induction of differentiation of human myeloid leukemias: surface changes probed with monoclonal antibodies.
Topics: Antibodies, Monoclonal; Antigens, Surface; Cell Differentiation; Cell Line; Culture Media; Dimethyl Sulfoxide; Humans; Leukemia, Myeloid, Acute; Lymphocytes; Tetradecanoylphorbol Acetate; Tretinoin | 1983 |
The effects of dexamethasone and tetradecanoyl phorbol acetate on plasminogen activator release by human acute myeloid leukemia cells.
Topics: Cell Survival; Cells, Cultured; Dexamethasone; DNA; Granulocytes; Humans; Leukemia, Myeloid, Acute; Phorbols; Plasminogen Activators; Tetradecanoylphorbol Acetate | 1983 |
Induction of differentiation of human acute non-lymphocytic leukemia cells in primary culture by inducers of differentiation of human myeloid leukemia cell line HL-60.
Topics: Adult; Aged; Cell Differentiation; Cell Line; Cells, Cultured; Child; Child, Preschool; Female; Granulocytes; Humans; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Macrophages; Male; Middle Aged; Monocytes; Tetradecanoylphorbol Acetate; Tretinoin | 1983 |
Induction of cytotoxic effector activity in the HL-60 promyelocytic cell line by incubation with phorbol myristate acetate: a model system of human spontaneous monocyte-mediated cytotoxicity.
Topics: Animals; Antimetabolites; Cell Line; Cell Transformation, Neoplastic; Cellobiose; Chickens; Cytotoxicity, Immunologic; Disaccharides; Humans; Kinetics; Leukemia, Myeloid, Acute; Models, Biological; Monocytes; Tetradecanoylphorbol Acetate | 1983 |
The effect of glutathione on HL-60 treated with dimethylsulfoxide, butyric acid or 12-O-tetradecanoylphorbol-13-acetate.
Topics: Butyrates; Butyric Acid; Cell Differentiation; Cell Division; Cell Line; Cell Survival; Dimethyl Sulfoxide; Glutathione; Humans; Leukemia, Myeloid, Acute; Phorbols; Tetradecanoylphorbol Acetate | 1983 |
Differentiation of HL-60 cells: cell volume and cell cycle changes.
Topics: Butyrates; Butyric Acid; Cell Count; Cell Cycle; Cell Transformation, Neoplastic; Dimethyl Sulfoxide; Flow Cytometry; Humans; Leukemia, Myeloid, Acute; Macrophages; Tetradecanoylphorbol Acetate; Tretinoin | 1983 |
Control of macrophage cell differentiation in human promyelocytic HL-60 leukemia cells by 1,25-dihydroxyvitamin D3 and phorbol-12-myristate-13-acetate.
Topics: Antibodies, Monoclonal; Calcitriol; Cell Differentiation; Cell Line; Dimethyl Sulfoxide; Humans; Leukemia, Myeloid, Acute; Macrophages; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Tetradecanoylphorbol Acetate | 1983 |
Rapid protein phosphorylation induced by phorbol ester in HL-60 cells. Unique alkali-stable phosphorylation of a 17,000-dalton protein detected by two-dimensional gel electrophoresis.
Topics: Cell Differentiation; Cell Line; Electrophoresis, Polyacrylamide Gel; Humans; Leukemia, Myeloid, Acute; Molecular Weight; Phorbols; Phosphorylation; Proteins; Tetradecanoylphorbol Acetate | 1983 |
Differentiation of human leukemia cells and its usefulness for clinical diagnosis.
Topics: Cell Differentiation; Clinical Laboratory Techniques; Diagnosis, Differential; Humans; Leukemia; Leukemia, Hairy Cell; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukemia, Plasma Cell; Tetradecanoylphorbol Acetate | 1983 |
Generation of procoagulant activity (PCA) by macrophage-like cells derived from acute and chronic myeloid leukaemia cells in response to phorbol esters.
Topics: Adolescent; Adult; Aged; Blood Coagulation; Blood Coagulation Disorders; Blood Coagulation Factors; Cell Differentiation; Cell Separation; Cells, Cultured; Child; Child, Preschool; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Macrophages; Middle Aged; Monocytes; Phorbols; Reference Values; Tetradecanoylphorbol Acetate | 1983 |
Functional and phenotypic characterization of two HL60 clones resistant to dimethylsulfoxide.
Topics: Cell Differentiation; Cell Line; Dimethyl Sulfoxide; Drug Resistance; Humans; Kinetics; Leukemia, Myeloid, Acute; Phenotype; Tetradecanoylphorbol Acetate; Tretinoin | 1983 |
Acetate utilization and fatty acid metabolism in phorbol ester and dimethyl sulfoxide-differentiated human leukemia cells.
Topics: Acetates; Cell Differentiation; Cells, Cultured; Dimethyl Sulfoxide; Fatty Acids; Granulocytes; Humans; Leukemia, Myeloid, Acute; Macrophages; Phorbols; Tetradecanoylphorbol Acetate | 1983 |
Cytotoxicity in promyelocytic cell lines.
Topics: Animals; Cytotoxicity, Immunologic; Humans; Leukemia, Myeloid, Acute; Mice; Tetradecanoylphorbol Acetate | 1983 |
[Differentiation induction of acute leukemia cells and its clinical usefulness].
Topics: Adolescent; Adult; Aged; Cell Differentiation; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Phorbols; Tetradecanoylphorbol Acetate | 1983 |
Double minute chromatin bodies and other chromosome alterations in human myeloid HL-60 leukemia cells susceptible or resistant to induction of differentiation by phorbol-12-myristate-13-acetate.
Topics: Cell Differentiation; Cell Line; Chromatin; Chromosome Aberrations; Chromosome Banding; Chromosome Disorders; Drug Resistance; Humans; Karyotyping; Leukemia, Myeloid, Acute; Muramidase; Phorbols; Tetradecanoylphorbol Acetate | 1983 |
1 alpha,25-dihydroxyvitamin D3 induces differentiation of human promyelocytic leukemia cells (HL-60) into monocyte-macrophages, but not into granulocytes.
Topics: Calcitriol; Cell Differentiation; Cell Line; Dexamethasone; Granulocytes; Humans; Kinetics; Leukemia, Myeloid, Acute; Macrophages; Monocytes; Tetradecanoylphorbol Acetate; Tretinoin | 1983 |
Rapid phosphorylation-dephosphorylation of specific proteins induced by phorbol ester in HL-60 cells. Further characterization of the phosphorylation of 17-kilodalton and 27-kilodalton proteins in myeloid leukemic cells and human monocytes.
Topics: Cell Line; Electrophoresis, Polyacrylamide Gel; Humans; Kinetics; Leukemia, Myeloid, Acute; Molecular Weight; Monocytes; Neoplasm Proteins; Phorbols; Phosphoproteins; Phosphorus Radioisotopes; Phosphorylation; Tetradecanoylphorbol Acetate | 1984 |
Divergence in cholesterol biosynthetic rates and 3-hydroxy-3-methylglutaryl-CoA reductase activity as a consequence of granulocyte versus monocyte-macrophage differentiation in HL-60 cells.
Topics: Cell Differentiation; Cell Line; Cholesterol; Dimethyl Sulfoxide; DNA Replication; Humans; Hydroxymethylglutaryl CoA Reductases; Kinetics; Leukemia, Myeloid, Acute; Macrophages; Monocytes; Tetradecanoylphorbol Acetate | 1984 |
Studies of the differentiation of promyelocytic cells by phorbol ester. II. A methylation inhibitor, 3-deazaadenosine, inhibits the induction of specific differentiation proteins. Lack of effect on early and late phosphorylation events.
Topics: Cell Adhesion; Cell Differentiation; Cell Line; Cell Movement; Electrophoresis, Polyacrylamide Gel; Humans; Isomerism; Kinetics; Leukemia, Myeloid, Acute; Membrane Proteins; Molecular Weight; Phorbols; Phosphorylation; Ribonucleosides; Tetradecanoylphorbol Acetate; Tubercidin | 1984 |
Studies of the differentiation of promyelocytic cells by phorbol ester. I. Induction of discrete membrane proteins characteristic of monocytes and expression of motility functions in HL-60 cells following differentiation by phorbol ester.
Topics: Cell Differentiation; Cell Line; Cell Movement; Electrophoresis, Polyacrylamide Gel; Humans; Kinetics; Leukemia, Myeloid, Acute; Lymphocytes; Macrophages; Membrane Proteins; Molecular Weight; Monocytes; Phorbols; Tetradecanoylphorbol Acetate | 1984 |
Glycosaminoglycan synthesis during differentiation of HL60/HGPRT-leukemia cells induced by dimethyl sulfoxide and 12-O-tetradecanoylphorbol-13-acetate.
Topics: Cell Differentiation; Cell Line; Dimethyl Sulfoxide; Glycosaminoglycans; Humans; Hypoxanthine Phosphoribosyltransferase; Kinetics; Leukemia, Myeloid, Acute; Phorbols; Tetradecanoylphorbol Acetate; Time Factors | 1984 |
Production of a cytotoxin from phorbol myristate acetate-treated human promyelocytes.
Topics: Animals; Cell Line; Cytotoxins; Dactinomycin; Embryo, Mammalian; Fibroblasts; HeLa Cells; Humans; Kinetics; L Cells; Leukemia, Myeloid, Acute; Mice; Phorbols; Skin; Skin Physiological Phenomena; Tetradecanoylphorbol Acetate | 1984 |
[Induction of differentiation of human myelomonocytic cell lines by chemical inducers: analysis of surface antigens with monoclonal antibodies].
Topics: Antibodies, Monoclonal; Antigens, Surface; Cell Differentiation; Cell Line; Cells, Cultured; Granulocytes; Humans; Leukemia, Myeloid, Acute; Monocytes; Phorbols; Tetradecanoylphorbol Acetate; Tretinoin | 1984 |
Tumor promoting phorbol diesters: substrates for diacylglycerol lipase.
Topics: Animals; Carbon Radioisotopes; Cell Line; Humans; Kinetics; Leukemia, Myeloid, Acute; Lipoprotein Lipase; Male; Phorbols; Phospholipids; Rats; Substrate Specificity; Tetradecanoylphorbol Acetate; Tritium | 1984 |
Phosphorylation and dephosphorylation of human promyelocytic leukemia cell (HL-60) proteins by tumor promoter.
Topics: Autoradiography; Cells, Cultured; Electrophoresis, Polyacrylamide Gel; Humans; Leukemia, Myeloid, Acute; Molecular Weight; Neoplasm Proteins; Phorbols; Phosphorylation; Subcellular Fractions; Tetradecanoylphorbol Acetate | 1984 |
Development of membrane-potential responsiveness by myeloid leukemia cells during neutrophilic differentiation.
Topics: Cell Differentiation; Cell Line; Dimethyl Sulfoxide; Humans; Kinetics; Leukemia, Myeloid, Acute; Membrane Potentials; Neutrophils; Tetradecanoylphorbol Acetate; Tretinoin | 1984 |
Differential phosphorylation events associated with phorbol ester effects on acceleration versus inhibition of cell growth.
Topics: Animals; Blood Platelets; Carcinoma, Squamous Cell; Cell Division; Cell Line; Cells, Cultured; Humans; Leukemia, Myeloid, Acute; Lymphocytes; Mice; Mice, Inbred Strains; Molecular Weight; Phorbols; Phosphoproteins; Phosphorylation; Proteins; Skin; Tetradecanoylphorbol Acetate | 1984 |
Membrane lipid dynamics in human promyelocytic leukemia cells sensitive and resistant to 12-O-tetradecanoylphorbol-13-acetate induction of differentiation.
Topics: Cell Differentiation; Cell Division; Cell Line; Cell Membrane; Drug Resistance; Fluorescence Polarization; Genetic Variation; Humans; Leukemia, Myeloid, Acute; Membrane Fluidity; Membrane Lipids; Muramidase; Phorbols; Tetradecanoylphorbol Acetate | 1984 |
Comparison of in vitro and in vivo differentiation of myeloblastic leukemia of the RFM/Un mouse.
Topics: Animals; Caenorhabditis elegans Proteins; Carrier Proteins; Cell Differentiation; Cell Line; Dexamethasone; Dimethyl Sulfoxide; DNA Replication; Female; Leukemia, Experimental; Leukemia, Myeloid, Acute; Mice; Mice, Inbred Strains; Muramidase; Phorbol Esters; Protein Kinase C; Receptors, Drug; Receptors, Immunologic; Tetradecanoylphorbol Acetate; Tretinoin | 1984 |
Lectin receptor proximity on HL-60 leukemia cells determined by fluorescence energy transfer using flow cytometry.
Topics: Cell Line; Dimethyl Sulfoxide; Energy Transfer; Flow Cytometry; Fluorescence; Humans; Leukemia, Myeloid, Acute; Receptors, Mitogen; Tetradecanoylphorbol Acetate; Tissue Distribution | 1984 |
Structure-activity studies on synthetic analogues (indolactams) of the tumor promoter teleocidin.
Topics: Animals; Caenorhabditis elegans Proteins; Carcinogens; Carrier Proteins; Cell Adhesion; Cell Line; Enzyme Induction; Humans; Indoles; Kinetics; Lactams; Leukemia, Myeloid, Acute; Mice; Ornithine Decarboxylase; Protein Kinase C; Receptors, Drug; Receptors, Immunologic; Skin; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1984 |
Specific alterations in the pattern of histone-3 synthesis during conversion of human leukemic cells to terminally differentiated cells in culture.
Topics: Acetamides; Cell Differentiation; Cell Line; Dimethyl Sulfoxide; Histones; Humans; Interphase; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Macrophages; Tetradecanoylphorbol Acetate | 1984 |
Serological analysis of cell surface antigens of HL-60 cells before and after treatment with a phorbol ester tumor promoter.
Topics: Antibodies, Monoclonal; Antigens, Neoplasm; Antigens, Surface; Blood Platelets; Cell Line; Cell Membrane; Humans; Leukemia, Myeloid, Acute; Microscopy, Electron; Phorbols; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1983 |
Inhibition of development of characteristic indices of myeloid differentiation by a factor released from a tetraploid variant of the human promyelocytic cell line, HL-60.
Topics: Animals; Cell Differentiation; Cell Line; Colony-Stimulating Factors; Genetic Variation; Humans; Leukemia, Myeloid, Acute; Mice; Polyploidy; Tetradecanoylphorbol Acetate | 1983 |
Induction of antibody-dependent and nonspecific tumor killing in human monocytic leukemia cells by nonlymphocyte factors and phorbol ester.
Topics: Antibody-Dependent Cell Cytotoxicity; Cell Line; Humans; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lymphoma, Large B-Cell, Diffuse; Phagocytosis; Phorbols; Receptors, Complement; Receptors, Fc; Tetradecanoylphorbol Acetate; Urinary Bladder Neoplasms | 1982 |
Induction of differentiation of human promyelocytic leukemia (HL-60) cells by teleocidin and phorbol-12-myristate-13-acetate.
Topics: Alkaloids; Carcinogens; Cell Differentiation; Cells, Cultured; DNA, Neoplasm; Humans; Leukemia, Myeloid, Acute; Lyngbya Toxins; Phorbols; Tetradecanoylphorbol Acetate | 1982 |
The control of phospholipid methylation by phorbol diesters in differentiating human myeloid HL-60 leukemia cells.
Topics: Alkaloids; Cell Differentiation; Cell Line; Humans; Leukemia, Myeloid, Acute; Lyngbya Toxins; Methylation; Methyltransferases; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Phosphatidylethanolamine N-Methyltransferase; Phospholipids; Tetradecanoylphorbol Acetate | 1982 |
Differentiation of human leukemias in response to 12-0-tetradecanoylphorbol-13-acetate in vitro.
Topics: Cell Adhesion; Cell Aggregation; Cell Transformation, Neoplastic; Esterases; Humans; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Phagocytosis; Phorbols; Tetradecanoylphorbol Acetate | 1980 |
Effect of maturation on the response of human promyelocytic leukemia cells (HL-60) to the tumor promoter 12-o-tetradecanolyphorbol-13-acetate.
Topics: Cell Differentiation; Fibrinolysis; Hexosephosphates; Humans; Intracellular Membranes; Leukemia, Myeloid, Acute; NADH, NADPH Oxidoreductases; NADPH Oxidases; Oxygen Consumption; Phorbols; Plasminogen; Receptors, Complement; Receptors, Drug; Tetradecanoylphorbol Acetate | 1980 |
Decreased membrane fluidity during differentiation of human promyelocytic leukemia cells in culture.
Topics: Cell Membrane; Cell Transformation, Neoplastic; Cells, Cultured; Cholesterol; Dimethyl Sulfoxide; Humans; Leukemia, Myeloid, Acute; Membrane Lipids; Phospholipids; Tetradecanoylphorbol Acetate | 1980 |
Phorbol myristate acetate stimulates macrophage differentiation and replication and alters granulopoiesis and leukemogenesis in long-term bone marrow cultures.
Topics: Animals; Bone Marrow Cells; Cell Differentiation; Cells, Cultured; Granulocytes; Hematopoiesis; Leukemia, Myeloid, Acute; Macrophages; Mice; Phorbols; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Time Factors | 1980 |
[Changes of fibrinolytic activity of human HL60 acute leukemia cells responses to chemically induced differentiation].
Topics: Cell Differentiation; Cell Line; Dimethyl Sulfoxide; Fibrinolysis; Granulocytes; Humans; Leukemia, Myeloid, Acute; Tetradecanoylphorbol Acetate; Tretinoin | 1980 |
Dose-dependent effects of a tumor promotor on blast cell progenitors in human myeloblastic leukemia.
Topics: Cells, Cultured; Clone Cells; Dose-Response Relationship, Drug; Humans; Leukemia, Myeloid, Acute; Phorbols; Tetradecanoylphorbol Acetate | 1981 |
Tumour promoters induce macrophage differentiation in human myeloid cells from patients with acute and chronic myelogenous leukaemia.
Topics: Bone Marrow; Cell Differentiation; Cells, Cultured; Diterpenes; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Macrophages; Phorbols; Spleen; Tetradecanoylphorbol Acetate | 1981 |
Alterations in polyamine levels induced by phorbol diesters and other agents that promote differentiation in human promyelocytic leukemia cells.
Topics: Cell Differentiation; Cell Line; Humans; Kinetics; Leukemia, Myeloid, Acute; Muramidase; Phorbol Esters; Phorbols; Polyamines; Putrescine; Spermidine; Spermine; Tetradecanoylphorbol Acetate | 1981 |
Down regulation of specific binding of [20-3H]phorbol 12,13-dibutyrate and phorbol ester-induced differentiation of human promyelocytic leukemia cells.
Topics: Binding Sites; Binding, Competitive; Carcinogens; Cell Differentiation; Cell Line; Humans; Kinetics; Leukemia, Myeloid, Acute; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Tetradecanoylphorbol Acetate | 1981 |
Early changes in phosphatidylcholine metabolism in human acute promyelocytic leukemia cells stimulated to differentiate by phorbol ester.
Topics: Cell Transformation, Neoplastic; Humans; Leukemia, Myeloid, Acute; Methylation; Phorbol Esters; Phorbols; Phosphatidylcholines; Phospholipids; Tetradecanoylphorbol Acetate; Time Factors | 1981 |
Identification of a population of bipotent stem cells in the HL60 human promyelocytic leukemia cell line.
Topics: Cell Differentiation; Cell Line; Cells, Cultured; Clone Cells; Dimethylformamide; Hematopoietic Stem Cells; Humans; Kinetics; Leucine; Leukemia, Myeloid, Acute; Macrophages; Tetradecanoylphorbol Acetate | 1981 |
Terminal differentiation surface antigens of myelomonocytic cells are expressed in human promyelocytic leukemia cells (HL60) treated with chemical inducers.
Topics: Animals; Antibodies, Monoclonal; Antigens, Surface; Blood Cells; Bone Marrow; Bone Marrow Cells; Cell Transformation, Neoplastic; Dimethyl Sulfoxide; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Mice; Rabbits; Tetradecanoylphorbol Acetate; Tretinoin | 1981 |
Isoenzymes of lactate dehydrogenase in human leukemic cells in culture treated with inducers of differentiation.
Topics: Acetamides; Butyrates; Cell Differentiation; Cell Line; Cell Survival; Diamines; Dimethyl Sulfoxide; Erythropoiesis; Granulocytes; Hematopoiesis; Humans; Isoenzymes; L-Lactate Dehydrogenase; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Tetradecanoylphorbol Acetate; Tretinoin | 1981 |
1 alpha,25-Dihydroxyvitamin D3 induces differentiation of human myeloid leukemia cells.
Topics: Calcitriol; Cell Differentiation; Cell Line; Dactinomycin; Dimethyl Sulfoxide; Humans; Kinetics; Leukemia, Myeloid, Acute; Tetradecanoylphorbol Acetate | 1981 |
Release of platelet-activating factor from HL-60 human leukemic cells following macrophage-like differentiation.
Topics: Cell Line; Cell Transformation, Neoplastic; Humans; Leukemia, Myeloid, Acute; Leukocytes; Lysophosphatidylcholines; Macrophages; Platelet Activating Factor; Receptors, Complement; Tetradecanoylphorbol Acetate | 1982 |
Decreased synthesis of high-molecular-weight glycopeptides in human promyelocytic leukemic cells (HL-60) during phorbol ester-induced macrophage differentiation.
Topics: Cell Adhesion; Cell Differentiation; Cell Line; Chromatography, DEAE-Cellulose; Chromatography, Gel; Glycopeptides; Granulocytes; Humans; Leukemia, Myeloid, Acute; Lymphocytes; Macrophages; Membrane Proteins; Molecular Weight; Monocytes; Phorbols; Tetradecanoylphorbol Acetate | 1982 |
Expression of normal monocyte-macrophage differentiation antigens on HL60 promyelocytes undergoing differentiation induced by leukocyte-conditioned medium or phorbol diester.
Topics: Antigens, Surface; Cell Differentiation; Cell Line; Culture Media; Leukemia, Myeloid, Acute; Leukocytes; Macrophages; Monocytes; Phorbols; Tetradecanoylphorbol Acetate | 1981 |
Ornithine decarboxylase: essential in proliferation but not differentiation of human promyelocytic leukemia cells.
Topics: Carboxy-Lyases; Cell Adhesion; Cell Differentiation; Cell Division; Cells, Cultured; Female; Granulocytes; Humans; Leukemia, Myeloid, Acute; Macrophages; Ornithine Decarboxylase; Polyamines; Tetradecanoylphorbol Acetate; Tretinoin | 1982 |
Cell differentiation, alterations in polyamine levels, and specific binding of phorbol diesters in cultured human cells.
Topics: Binding Sites; Carcinogens; Cell Differentiation; Cell Line; Cell Membrane; Humans; Leukemia, Myeloid, Acute; Melanoma; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Polyamines; Tetradecanoylphorbol Acetate | 1982 |
Modification by serum of differentiation of cultured human myeloid leukemia cells in response to 12-O-tetradecanoylphorbol-13-acetate.
Topics: Animals; Blood Physiological Phenomena; Cells, Cultured; Culture Media; Humans; Leukemia, Experimental; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Macrophages; Phorbols; Tetradecanoylphorbol Acetate | 1982 |
Physicochemical and functional changes in human leukemic cell line HL-60.
Topics: Cell Differentiation; Cell Line; Cell Separation; Complement C3b; Dimethyl Sulfoxide; Granulocytes; Hematopoiesis; Humans; Leukemia, Myeloid, Acute; Luminescent Measurements; Phagocytosis; Receptors, Fc; Surface Properties; Tetradecanoylphorbol Acetate | 1982 |
Kinetics of appearance of differentiation-associated characteristics in ML-1, a line of human myeloblastic leukemia cells, after treatment with 12-O-tetradecanoylphorbol-13-acetate, dimethyl sulfoxide or 1-beta-D-arabinofuranosylcytosine.
Topics: Cell Cycle; Cell Differentiation; Cell Line; Cell Survival; Dimethyl Sulfoxide; Humans; Kinetics; Leukemia, Myeloid, Acute; Phorbols; Tetradecanoylphorbol Acetate; Vidarabine | 1982 |
Variant cell lines from the human promyelocyte line HL60.
Topics: Cell Division; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Clone Cells; Dimethyl Sulfoxide; Humans; Karyotyping; Leukemia, Myeloid, Acute; Microscopy, Electron; Phenotype; Tetradecanoylphorbol Acetate | 1982 |
Exposure to phorbol diester (TPA) in vitro as an aid in the classification of blasts in human myelogenous and lymphoid leukemias: in vitro differentiation, growth patterns, and ultrastructural observations.
Topics: Histocytochemistry; Humans; In Vitro Techniques; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukocytes; Phorbols; Tetradecanoylphorbol Acetate | 1982 |
Modulation of the maturation of human leukemic promyelocytes (HL-60) to granulocytes or macrophages.
Topics: Cell Differentiation; Cell Line; Dimethyl Sulfoxide; Granulocytes; Humans; Leukemia, Myeloid, Acute; Macrophages; Monocytes; Tetradecanoylphorbol Acetate | 1982 |
Induction of differentiation of human myeloid leukemias by phorbol diesters: phenotypic changes and mode of action.
Topics: Animals; Antibodies, Monoclonal; Binding Sites; Cell Differentiation; Cell Division; Cell Line; Cell Membrane; Humans; Interphase; Leukemia, Experimental; Leukemia, Myeloid, Acute; Phenotype; Phorbols; Tetradecanoylphorbol Acetate; Time Factors; Transferrin | 1982 |
[Decrease of insulin binding to human acute leukemic cells during chemically induced differentiation].
Topics: Cell Differentiation; Cell Line; Dimethyl Sulfoxide; Granulocytes; Humans; Insulin; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Macrophages; Receptor, Insulin; Tetradecanoylphorbol Acetate; Tretinoin | 1980 |
Modulation of cell competence for induction of differentiation in myeloid leukemic cells.
Topics: Animals; Cell Differentiation; Concanavalin A; Culture Media; Dexamethasone; Hematopoiesis; Insulin; Leukemia, Experimental; Leukemia, Myeloid, Acute; Lipopolysaccharides; Mice; Tetradecanoylphorbol Acetate | 1982 |
Effect of 5637-conditioned medium and recombinant cytokines on P-glycoprotein expression in a human GM-CSF-dependent leukemic myeloid cell line.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Cell Differentiation; Culture Media, Conditioned; Cytokines; Drug Resistance, Multiple; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-1; Interleukin-3; Leukemia, Myeloid, Acute; Molecular Sequence Data; Recombinant Proteins; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Urinary Bladder Neoplasms | 1995 |
Identification and characterization of the human myeloperoxidase promoter.
Topics: Base Sequence; Chromosome Mapping; Dimethyl Sulfoxide; DNA, Neoplasm; Gene Deletion; Genetic Complementation Test; HeLa Cells; Humans; Introns; Leukemia, Erythroblastic, Acute; Leukemia, Myeloid, Acute; Molecular Sequence Data; Peroxidase; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Promoter Regions, Genetic; Sensitivity and Specificity; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1995 |
Soluble interleukin-2 receptor, soluble CD8 and soluble intercellular adhesion molecule-1 levels in hematologic malignancies.
Topics: Antigens, CD; Biomarkers; Biomarkers, Tumor; CD8 Antigens; Cell Adhesion Molecules; Cell Line; Enzyme-Linked Immunosorbent Assay; Humans; Intercellular Adhesion Molecule-1; Leukemia; Leukemia, Hairy Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid, Acute; Leukemia, Prolymphocytic; Leukemia, T-Cell; Mycosis Fungoides; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Receptors, Interleukin-2; Recurrence; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Near-tetraploid poorly differentiated acute myeloid leukemia M0 diagnosed by short-term cultures with a phorbol ester TPA.
Topics: Aged; Cell Differentiation; DNA, Neoplasm; Female; Humans; Immunophenotyping; Leukemia, Myeloid, Acute; Male; Middle Aged; Polyploidy; Tetradecanoylphorbol Acetate | 1994 |
Development of a H(+)-selective conductance during granulocytic differentiation of HL-60 cells.
Topics: Amino Acid Sequence; Antibodies; Cell Differentiation; Cell Line; Dimethyl Sulfoxide; Electric Conductivity; Fluoresceins; Fluorescent Dyes; Gene Expression; Humans; Hydrogen-Ion Concentration; Immunoblotting; Leukemia, Myeloid, Acute; Molecular Sequence Data; Molecular Weight; NADH, NADPH Oxidoreductases; NADPH Oxidases; Peptides; Spectrometry, Fluorescence; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Interplay between differentiation and cell cycle arrest at G1 in phorbol diester-treated human myelocytic leukemia cells.
Topics: Cell Differentiation; G1 Phase; Humans; Leukemia, Myeloid, Acute; Phorbol 12,13-Dibutyrate; Phorbol Esters; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Interleukin 6 induces DNA binding activity of AP1 in M1 myeloblastic cells but not in a growth resistant cell derivative.
Topics: Animals; Base Sequence; Cell Differentiation; Cell Division; Clone Cells; DNA-Binding Proteins; Genes, jun; Interferon Type I; Interleukin-6; Leukemia, Myeloid, Acute; Mice; Molecular Sequence Data; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription Factors; Transforming Growth Factor beta; Tumor Cells, Cultured | 1993 |
Alterations in a voltage-gated K+ current during the differentiation of ML-1 human myeloblastic leukemia cells.
Topics: 4-Aminopyridine; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Humans; Ion Channel Gating; Leukemia, Myeloid, Acute; Membrane Potentials; Potassium Channels; Tetradecanoylphorbol Acetate; Tetraethylammonium Compounds; Tumor Cells, Cultured | 1993 |
Distinct temporal patterns of defensin mRNA regulation during drug-induced differentiation of human myeloid leukemia cells.
Topics: Acetamides; Biomarkers; Blood Proteins; Cell Differentiation; Cycloheximide; Cytokines; Dactinomycin; Defensins; Dimethyl Sulfoxide; Dimethylformamide; DNA, Complementary; Enzyme Inhibitors; Gene Expression Regulation, Leukemic; Genistein; Granulocyte Colony-Stimulating Factor; Granulocytes; HL-60 Cells; Humans; Interferon-gamma; Isoflavones; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Lymphocytes; Lymphoma, Large B-Cell, Diffuse; Neoplasm Proteins; Recombinant Proteins; RNA Processing, Post-Transcriptional; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Transcription, Genetic; Tretinoin; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1996 |
Establishment and characterization of two novel cytokine-responsive acute myeloid and monocytic leukemia cell lines, MUTZ-2 and MUTZ-3.
Topics: Acid Phosphatase; Adult; Antineoplastic Agents; Base Sequence; Cell Differentiation; Cell Division; Chromosome Aberrations; Cytokines; Esterases; Hematopoietic Cell Growth Factors; Humans; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Middle Aged; Molecular Sequence Data; Peroxidase; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1996 |
[The effect of the secretory products of mononuclear phagocytes from patients in a control group and from patients suffering from acute nonlymphoblastic leukemias on the cells of the U-937 monoblastic line].
Topics: Bone Marrow Cells; Cell Differentiation; Cell Division; Humans; Leukemia, Myeloid, Acute; Lymphoma, Large B-Cell, Diffuse; Macrophages; Monocytes; Monokines; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1996 |
Effect of (-)-epigallocatechin gallate on leukemic blast cells from patients with acute myeloblastic leukemia.
Topics: Blast Crisis; Catechin; Cell Division; Cell Line; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Tea; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1997 |
Regulation of BCL-6 gene expression in human myeloid/monocytoid leukemic cells.
Topics: Adult; Cell Differentiation; Cell Nucleus; Cycloheximide; Dactinomycin; DNA-Binding Proteins; Flow Cytometry; Gene Expression Regulation, Neoplastic; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-6; Tetradecanoylphorbol Acetate; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured | 1997 |
Identification of immediate early genes during TPA-induced human myeloblastic leukemia ML-1 cell differentiation.
Topics: Cell Differentiation; Cycloheximide; DNA, Neoplasm; Gene Expression Regulation, Leukemic; Genes, Immediate-Early; Genes, Neoplasm; Humans; Leukemia, Myeloid, Acute; Protein Synthesis Inhibitors; RNA, Messenger; RNA, Neoplasm; Sequence Analysis, DNA; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1998 |
Expression of the antiapoptotic MCL1 gene product is regulated by a mitogen activated protein kinase-mediated pathway triggered through microtubule disruption and protein kinase C.
Topics: Calcium-Calmodulin-Dependent Protein Kinases; Cell Death; Cisplatin; Colchicine; Humans; Leukemia, Myeloid, Acute; Microtubules; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; Paclitaxel; Phosphorylation; Protein Kinase C; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vinblastine | 1998 |
Modulation of homeobox B6 and B9 genes expression in human leukemia cell lines during myelomonocytic differentiation.
Topics: Cell Differentiation; Cell Division; Gene Expression Regulation, Leukemic; Genes, Homeobox; Granulocyte Colony-Stimulating Factor; HL-60 Cells; Homeodomain Proteins; Humans; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Neoplasm Proteins; Neoplastic Stem Cells; Oligonucleotides, Antisense; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1998 |
A requirement for K+-channel activity in growth factor-mediated extracellular signal-regulated kinase activation in human myeloblastic leukemia ML-1 cells.
Topics: Calcium-Calmodulin-Dependent Protein Kinases; Carcinogens; Enzyme Activation; Epidermal Growth Factor; G1 Phase; Humans; Leukemia, Myeloid, Acute; Mitogen-Activated Protein Kinase 1; Potassium Channels; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1999 |
The receptor protein tyrosine phosphatase, PTP-RO, is upregulated during megakaryocyte differentiation and Is associated with the c-Kit receptor.
Topics: Adolescent; Animals; beta Catenin; Cadherins; Cell Differentiation; Cell Line; Chlorocebus aethiops; COS Cells; Cytoskeletal Proteins; Enzyme Induction; Female; Gene Expression Regulation, Developmental; Hematopoiesis; Humans; Leukemia, Myeloid, Acute; Megakaryocytes; Mice; Oligonucleotides, Antisense; Phosphorylation; Protein Processing, Post-Translational; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins c-kit; Receptor-Like Protein Tyrosine Phosphatases, Class 2; Receptor-Like Protein Tyrosine Phosphatases, Class 3; Recombinant Fusion Proteins; Stem Cell Factor; Tetradecanoylphorbol Acetate; Trans-Activators; Transfection; Tumor Cells, Cultured | 1999 |
Okadaic acid suppresses TPA-induced differentiation by stimulating G1/S transition in human myeloblastic leukaemia ML-1 cells.
Topics: Cell Differentiation; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; G1 Phase; Humans; Leukemia, Myeloid, Acute; Lipopolysaccharide Receptors; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Retinoblastoma Protein; S Phase; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2000 |
KG-1 and KG-1a model the p15 CpG island methylation observed in acute myeloid leukemia patients.
Topics: Bone Marrow; Cell Cycle Proteins; CpG Islands; Cyclin-Dependent Kinase Inhibitor p15; Cyclin-Dependent Kinase Inhibitor p16; DNA Methylation; DNA Primers; Histones; HL-60 Cells; Humans; Immunoblotting; Leukemia, Myeloid, Acute; Polymerase Chain Reaction; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Sulfites; Tetradecanoylphorbol Acetate; Transcription Factors; Tumor Cells, Cultured; Tumor Suppressor Proteins | 2001 |
RasGRP4 is a novel Ras activator isolated from acute myeloid leukemia.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cytokines; Genes, ras; Guanine Nucleotide Exchange Factors; Humans; Leukemia, Myeloid, Acute; Molecular Sequence Data; ras Guanine Nucleotide Exchange Factors; Rats; Tetradecanoylphorbol Acetate | 2002 |
Ultraviolet-induced junD activation and apoptosis in myeloblastic leukemia ML-1 cells.
Topics: Apoptosis; Blotting, Northern; Blotting, Western; Caspase 3; Caspases; Cell Death; Culture Media, Serum-Free; Enzyme Activation; Enzyme Inhibitors; Humans; Leukemia, Myeloid, Acute; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Precipitin Tests; Protein Kinase C; Proto-Oncogene Proteins c-jun; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors; Transfection; Tumor Cells, Cultured; Ultraviolet Rays | 2002 |
Induction of differentiation in human promyelocytic leukemia cells by tumor promoters.
Topics: Cell Adhesion; Cell Differentiation; Cell Line; Diterpenes; Humans; Leukemia, Myeloid, Acute; Phorbol Esters; Phorbols; Tetradecanoylphorbol Acetate | 1979 |
A switch toward demethylation is associated with the expression of myeloperoxidase in acute myeloblastic and promyelocytic leukemias.
Topics: Blotting, Northern; Blotting, Southern; DNA Probes; DNA, Neoplasm; Gene Expression; Humans; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Methylation; Peroxidase; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
Characterization, growth, and differentiation of a human myeloid leukemia cell line, TI-1 cell.
Topics: Aneuploidy; Antigens, Differentiation; Antigens, Differentiation, Myelomonocytic; Cell Differentiation; Cell Division; Chromosome Banding; Culture Media; Hemin; Humans; Karyotyping; Leukemia, Myeloid, Acute; Male; Microscopy, Electron; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
Induction of monocytic differentiation by tumor necrosis factor in phorbol ester-resistant KG-1a cells.
Topics: Blotting, Northern; Cell Adhesion; Cell Adhesion Molecules; Cell Transformation, Neoplastic; Flow Cytometry; Gene Expression Regulation; Humans; In Vitro Techniques; Leukemia, Myeloid, Acute; Macrophage Colony-Stimulating Factor; Monocytes; Phospholipases A; Phospholipases A2; RNA; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1990 |
A novel human myeloid leukemia cell line, NKM-1, coexpressing granulocyte colony-stimulating factor receptors and macrophage colony-stimulating factor receptors.
Topics: Adult; Antigens, Surface; Blotting, Northern; Cell Division; Cerebrospinal Fluid; Dose-Response Relationship, Drug; Humans; Interleukin-3; Leukemia, Myeloid, Acute; Macrophage Colony-Stimulating Factor; Male; Receptor, Macrophage Colony-Stimulating Factor; Receptors, Granulocyte Colony-Stimulating Factor; RNA; Tetradecanoylphorbol Acetate | 1990 |
The involvement of protein kinase C in mediating growth suppressive signals of interferons in hematopoietic cells.
Topics: Animals; Burkitt Lymphoma; Cell Cycle; Cell Line; G1 Phase; Hematopoiesis; Humans; Interferons; Leukemia, Myeloid, Acute; Mice; Protein Kinase C; Proto-Oncogene Proteins c-myc; Resting Phase, Cell Cycle; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transforming Growth Factor beta | 1991 |
The effect of the insecticide heptachlor on ras proto-oncogene expression in human myeloblastic leukemia (ML-1) cells.
Topics: Actins; Base Sequence; Blood; Culture Media; Gene Expression; Genes, ras; Heptachlor; Humans; Leukemia, Myeloid, Acute; Molecular Sequence Data; Polymerase Chain Reaction; Proto-Oncogene Mas; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
Expression and regulation of IL-4 receptors on human monocytes and acute myeloblastic leukemic cells.
Topics: Cell Division; Diglycerides; Down-Regulation; Humans; Interleukin-4; Leukemia, Myeloid, Acute; Monocytes; Protein Kinase C; Receptors, Interleukin-4; Receptors, Mitogen; Tetradecanoylphorbol Acetate | 1991 |
Expression of IMP dehydrogenase in differentiating HL-60 cells.
Topics: Blotting, Northern; Blotting, Western; Cell Differentiation; Cell Division; Humans; IMP Dehydrogenase; In Vitro Techniques; Ketone Oxidoreductases; Leukemia, Myeloid, Acute; Mycophenolic Acid; Ribonucleotides; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Tretinoin; Tumor Cells, Cultured | 1990 |
Tumor necrosis factor-alpha, transforming growth factor-beta, and tetradecanoylphorbol acetate: competence factors for ML-1 human myeloblastic leukemia cell differentiation.
Topics: Cell Differentiation; Humans; Leukemia, Myeloid, Acute; Tetradecanoylphorbol Acetate; Time Factors; Transforming Growth Factor alpha; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1991 |
Differentiation-associated expression of two functionally distinct classes of granulocyte-macrophage colony-stimulating factor receptors by human myeloid cells.
Topics: Binding, Competitive; Bone Marrow; Bone Marrow Cells; Cell Differentiation; Colony-Stimulating Factors; Cross-Linking Reagents; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Substances; Humans; In Vitro Techniques; Interleukin-3; Leukemia, Myeloid, Acute; Monocytes; Neutrophils; Receptors, Cell Surface; Receptors, Colony-Stimulating Factor; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Control of actin conformation in AML myeloblasts: the effects of bryostatin and TPA.
Topics: Actins; Adult; Aged; Antineoplastic Agents; Bone Marrow; Bryostatins; Female; Flow Cytometry; Humans; Lactones; Leukemia, Myeloid, Acute; Macrolides; Male; Microscopy, Electron, Scanning; Middle Aged; Protein Conformation; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Improved coupling between proliferation-arrest and differentiation-induction in ML-1 human myeloblastic leukemia cells.
Topics: Cell Cycle; Cell Differentiation; Cell Division; Cell Line; Culture Media; DNA, Neoplasm; Gene Expression; Humans; Insulin; Kinetics; Leukemia, Myeloid, Acute; Tetradecanoylphorbol Acetate; Transferrin | 1990 |
A regulatory role for tumor necrosis factor (TNF) in ML-1 human myeloblastic leukemia cell maturation.
Topics: Cell Differentiation; Drug Synergism; Feedback; Humans; Leukemia, Myeloid, Acute; Macrophages; Monocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1990 |
Decreased expression of type II protein kinase C in HL-60 variant cells resistant to induction of cell differentiation by phorbol diester.
Topics: Blotting, Western; Calcium; Cell Compartmentation; Cell Differentiation; Diglycerides; Enzyme Activation; Humans; Isoenzymes; Leukemia, Myeloid, Acute; Protein Kinase C; Subcellular Fractions; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Differentiation of myeloid cells is accompanied by increased levels of pp60c-src protein and kinase activity.
Topics: Cell Differentiation; Cell Line; Humans; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Monocytes; Neoplasm Proteins; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins pp60(c-src); Tetradecanoylphorbol Acetate | 1986 |
Enhancement of phorbol diester-induced HL-60-mediated cytotoxicity by retinoic acid, dimethyl sulfoxide, and 5-azacytidine.
Topics: Azacitidine; Cell Differentiation; Cell Line; Cytotoxicity, Immunologic; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Leukemia, Myeloid, Acute; Macrophages; Monocytes; Phorbol 12,13-Dibutyrate; Phorbol Esters; Tetradecanoylphorbol Acetate; Tretinoin | 1986 |
Detection of c-fms and CSF-1 RNA by in situ hybridization.
Topics: Cell Differentiation; Colony-Stimulating Factors; Humans; Leukemia, Myeloid, Acute; Monocytes; Nucleic Acid Hybridization; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogenes; RNA; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1987 |
Colony-stimulating factor gene expression in human acute myeloblastic leukemia cells is posttranscriptionally regulated.
Topics: Blotting, Northern; Cell Nucleus; Colony-Stimulating Factors; Cycloheximide; DNA, Neoplasm; Gene Expression Regulation; Gene Rearrangement; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Substances; Humans; Leukemia, Myeloid, Acute; Macrophage Colony-Stimulating Factor; RNA Processing, Post-Transcriptional; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1989 |
Expression of c-jun protooncogene in human myelomonocytic cells.
Topics: Cells, Cultured; Cycloheximide; Dactinomycin; DNA-Binding Proteins; Gene Expression; Humans; Leukemia, Myeloid, Acute; Lipopolysaccharides; Monocytes; Neutrophils; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-jun; Proto-Oncogenes; Recombinant Proteins; Reference Values; RNA; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Transcription Factors; Tumor Necrosis Factor-alpha | 1989 |
[Human oncogene expression in the normal state and in various blood system diseases].
Topics: Antineoplastic Agents; Gene Expression Regulation, Leukemic; Humans; Leukemia; Leukemia, Myeloid, Acute; Leukocytes, Mononuclear; Nucleic Acid Hybridization; Oncogenes; Pancytopenia; Phytohemagglutinins; RNA; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1989 |
Heterogenous response of primary cultured bone marrow cells of patients with different varieties of leukemia to differentiation inducers.
Topics: Adolescent; Adult; Aged; Bone Marrow; Child; Female; Harringtonines; Homoharringtonine; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1989 |
Transcriptional regulation of c-myc during chemically induced differentiation of HL-60 cultures.
Topics: Cell Differentiation; Cell Line; Cell Nucleus; Dimethyl Sulfoxide; Humans; Leukemia, Myeloid, Acute; Oncogenes; RNA; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1985 |
Induction of protein kinase C translocation and cell differentiation in ML-1 human myeloblastic leukemic cells by tumor necrosis factor-alpha, transforming growth factor-beta, or tetradecanoylphorbol acetate.
Topics: Cell Differentiation; Cell Line; Enzyme Induction; Humans; Kinetics; Leukemia, Myeloid, Acute; Protein Kinase C; Protein Processing, Post-Translational; Recombinant Proteins; Tetradecanoylphorbol Acetate; Transforming Growth Factors; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1989 |
Differential responsiveness to phorbol esters correlates with differential expression of protein kinase C in KG-1 and KG-1a human myeloid leukemia cells.
Topics: Caenorhabditis elegans Proteins; Carrier Proteins; Cell Division; Cell Line; Gene Expression; Humans; Kinetics; Leukemia, Myeloid, Acute; Protein Kinase C; Receptors, Drug; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 1989 |
Changes in Na+-H+ exchange regulation upon granulocytic differentiation of HL60 cells.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Carrier Proteins; Cell Differentiation; Cell Line; Dimethyl Sulfoxide; Fluoresceins; Granulocytes; Humans; Hydrogen-Ion Concentration; Leukemia, Myeloid, Acute; NADH, NADPH Oxidoreductases; NADPH Oxidases; Protein Kinase C; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate | 1987 |
Induction of HL-60 monocytic cell differentiation promoted by a perturbation of DNA synthesis: hydroxyurea promotes action of TPA.
Topics: Cell Differentiation; Cell Division; Cell Line; Humans; Hydroxyurea; Kinetics; Leukemia, Myeloid, Acute; Superoxides; Tetradecanoylphorbol Acetate | 1988 |
Cooperative interactions of protein kinase C and cAMP-dependent protein kinase systems in human promyelocytic leukemia HL60 cells.
Topics: Biological Transport; Bucladesine; Cell Differentiation; Dinoprostone; Drug Synergism; Humans; Leukemia, Myeloid, Acute; Male; Membrane Proteins; Middle Aged; Neoplasm Proteins; Phosphorylation; Prostaglandins E; Protein Kinase C; Protein Kinases; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1988 |
Transcriptional regulation of myeloperoxidase gene expression in myeloid leukemia HL-60 cells during differentiation into granulocytes and macrophages.
Topics: Cell Differentiation; Dimethyl Sulfoxide; DNA; Enzyme Induction; Granulocytes; Humans; Leukemia, Myeloid, Acute; Macrophages; Male; Middle Aged; Neoplasm Proteins; Peroxidase; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myc; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 1988 |
Propionic acid-induced calcium mobilization in human neutrophils.
Topics: Calcium; Cell Line; Cholera Toxin; Humans; Hydrogen-Ion Concentration; Leukemia, Myeloid, Acute; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Propionates; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1988 |
Activation of the fructose 1,6-bisphosphatase gene by 1,25-dihydroxyvitamin D3 during monocytic differentiation.
Topics: Amino Acid Sequence; Base Sequence; Calcitriol; Clone Cells; Fructose-Bisphosphatase; Gene Expression Regulation; Humans; Leukemia, Myeloid, Acute; Molecular Sequence Data; Monocytes; Tetradecanoylphorbol Acetate | 1988 |
Transglutaminase activity increases in HL60 cells induced to differentiate with retinoic acid and TPA but not with DMSO.
Topics: Cell Differentiation; Cell Line; Dimethyl Sulfoxide; Humans; Leukemia, Myeloid, Acute; Macrophages; Monocytes; Phorbols; Tetradecanoylphorbol Acetate; Time Factors; Transglutaminases; Tretinoin | 1985 |
Expression of immunoglobulin lambda light chain by the promyelocytic cell line HL-60.
Topics: Antibodies, Neoplasm; B-Lymphocytes; Cell Differentiation; Cell Line; Gene Expression Regulation; Humans; Immunoglobulin Light Chains; Leukemia, Myeloid, Acute; Male; Poly A; RNA, Messenger; Tetradecanoylphorbol Acetate | 1986 |
Expression of leukocyte adherence-related glycoproteins during differentiation of HL-60 promyelocytic leukemia cells.
Topics: Antigens, Surface; Cell Adhesion; Cell Differentiation; Cell Line; Glycoproteins; Granulocytes; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Macrophages; Monocytes; Neutrophils; Receptors, Complement; Receptors, Complement 3b; Tetradecanoylphorbol Acetate | 1987 |
Calcium influx and the Ca2+-calmodulin complex are involved in interferon-gamma-induced expression of HLA class II molecules on HL-60 cells.
Topics: Calcimycin; Calcium; Calmodulin; Cell Line; Egtazic Acid; HLA-D Antigens; Humans; Interferon-gamma; Leukemia, Myeloid, Acute; Receptors, Immunologic; Receptors, Interferon; RNA, Messenger; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1988 |
Dissociation of protein kinase C activation from phorbol ester-induced maturation of HL-60 leukemia cells.
Topics: Cell Differentiation; Cell Division; Cell Line; Diglycerides; Enzyme Activation; Humans; Leukemia, Myeloid, Acute; Neoplasm Proteins; Phorbols; Phosphatidylcholines; Phosphorylation; Protein Kinase C; Protein Kinases; Receptors, Cell Surface; Receptors, Transferrin; Tetradecanoylphorbol Acetate | 1985 |
The effect of the leukemic cell line HL60 and acute myeloblastic leukemic cells before and after induction of differentiation on normal pluripotent hematopoietic progenitors (CFU-GEMM).
Topics: Cell Differentiation; Cell Line; Cholecalciferol; Culture Techniques; Dimethyl Sulfoxide; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid, Acute; Leukocyte Count; Neoplastic Stem Cells; Phytohemagglutinins; Stem Cells; Tetradecanoylphorbol Acetate; Tretinoin | 1985 |
Mechanism of phorbol diester-induced regulation of surface transferrin receptor involves the action of activated protein kinase C and an intact cytoskeleton.
Topics: Cell Line; Cytoskeleton; Humans; Kinetics; Leukemia, Myeloid, Acute; Phorbols; Protein Kinase C; Protein Kinases; Receptors, Cell Surface; Receptors, Transferrin; Tetradecanoylphorbol Acetate; Transferrin | 1985 |
Induction of human HL-60 leukemic cell differentiation by immune interferon is accompanied by an increase in NADase activity and by a decrease in DNA-binding proteins.
Topics: Cell Differentiation; Cell Line; DNA-Binding Proteins; Humans; Interferon-gamma; Leukemia, Myeloid, Acute; NAD+ Nucleosidase; Neoplasm Proteins; Tetradecanoylphorbol Acetate | 1985 |
Detection of a countertranscript in promyelocytic leukemia cells HL60 during early differentiation by TPA.
Topics: Base Sequence; Cell Differentiation; Cell Line; Deoxyribonuclease HindIII; Deoxyribonucleases, Type II Site-Specific; DNA; DNA Restriction Enzymes; Humans; Leukemia, Myeloid, Acute; Nucleic Acid Hybridization; Phorbols; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Transcription, Genetic | 1985 |
Defective chemiluminescence response in differentiated HL60 cells due to impaired degranulation.
Topics: Cell Differentiation; Cell Line; Humans; Leukemia, Myeloid, Acute; Luminescent Measurements; Neutrophils; Nitroblue Tetrazolium; Peroxidase; Superoxides; Tetradecanoylphorbol Acetate | 1986 |
Expression of cytolytic functions in HL-60 leukaemic cells after induction of polymorphonuclear leukocyte differentiation.
Topics: Antibody-Dependent Cell Cytotoxicity; Cell Differentiation; Cell Line; Cytotoxicity, Immunologic; Dimethyl Sulfoxide; Humans; Leukemia, Myeloid, Acute; Neutrophils; Receptors, Fc; Superoxides; Tetradecanoylphorbol Acetate | 1986 |
12-o-Tetradecanoyl-phorbol-13-acetate-differentiated U937 cells express a macrophage-like profile of neutral proteinases. High levels of secreted collagenase and collagenase inhibitor accompany low levels of intracellular elastase and cathepsin G.
Topics: Cathepsin G; Cathepsins; Cell Differentiation; Cell Line; Chemotaxis; Cholecalciferol; Cyclic AMP; DNA; Humans; Leukemia, Myeloid, Acute; Macrophages; Microbial Collagenase; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pancreatic Elastase; Phorbols; Serine Endopeptidases; Tetradecanoylphorbol Acetate | 1986 |
Activation of the pp60c-src kinase during differentiation of monomyelocytic cells in vitro.
Topics: Avian Sarcoma Viruses; Cell Differentiation; Cell Line; Enzyme Activation; Enzyme Induction; Genes; Genes, Viral; Humans; Kinetics; Leukemia, Myeloid, Acute; Oncogene Protein pp60(v-src); Phosphorylation; Protein Kinases; Proto-Oncogene Mas; Proto-Oncogenes; Retroviridae Proteins; Tetradecanoylphorbol Acetate | 1986 |
Loss and reappearance of transferrin receptors in human leukemic cell lines.
Topics: Butyrates; Butyric Acid; Cell Differentiation; Cell Line; Dimethyl Sulfoxide; DNA Replication; Heme; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Receptors, Cell Surface; Receptors, Transferrin; Tetradecanoylphorbol Acetate; Transferrin; Tretinoin | 1986 |
Expression of the human c-fms proto-oncogene product (colony-stimulating factor-1 receptor) on peripheral blood mononuclear cells and choriocarcinoma cell lines.
Topics: Animals; Cell Line; Choriocarcinoma; Female; Glycoproteins; Humans; Leukemia, Myeloid, Acute; Monocytes; Oncogene Proteins, Viral; Pregnancy; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogenes; Rabbits; Receptors, Cell Surface; Receptors, Colony-Stimulating Factor; Tetradecanoylphorbol Acetate; Uterine Neoplasms | 1986 |
Role of intracellular calcium and protein kinase C in the endocytosis of transferrin and insulin by HL60 cells.
Topics: Calcium; Cell Line; Endocytosis; Humans; Insulin; Leukemia, Myeloid, Acute; Protein Kinase C; Receptor, Insulin; Receptors, Cell Surface; Receptors, Transferrin; Tetradecanoylphorbol Acetate; Transferrin | 1986 |
Regulation of myeloperoxidase gene expression by the tumor promoter 12-O-tetradecanoylphorbol-13-acetate in human leukemia HL-60 cells.
Topics: Cell Adhesion; Cell Division; Cell Line; Gene Expression Regulation; Humans; Leukemia, Myeloid, Acute; Peroxidase; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors | 1986 |
Regulation of 25-hydroxyvitamin D3 metabolism in a human promyelocytic leukemia cell line (HL-60): 1,25-dihydroxyvitamin D3 stimulates the synthesis of 24,25-dihydroxyvitamin D3.
Topics: Calcitriol; Cell Differentiation; Cell Line; Cholecalciferol; Dihydroxycholecalciferols; Humans; Leukemia, Myeloid, Acute; Macrophages; Periodic Acid; Tetradecanoylphorbol Acetate | 1986 |
The probable role of superoxide produced by blast cells in leukaemic cutaneous spreading.
Topics: Acute Disease; Adult; Aged; Female; Humans; In Vitro Techniques; Leukemia; Leukemia, Myeloid, Acute; Male; Middle Aged; Skin Neoplasms; Superoxides; Tetradecanoylphorbol Acetate | 1986 |
A correlation between phorbol diester-induced protein phosphorylation and superoxide anion generation in HL-60 cells during granulocytic maturation.
Topics: Cell Differentiation; Cell Line; Dimethyl Sulfoxide; Granulocytes; Humans; Kinetics; Leukemia, Myeloid, Acute; Molecular Weight; Neoplasm Proteins; Phosphoproteins; Phosphorylation; Protein Kinase C; Superoxides; Tetradecanoylphorbol Acetate | 1987 |
Magnesium deprivation inhibits the expression of differentiation-related phenotypes in human promyelocytic leukemia HL-60 cells.
Topics: Aclarubicin; Amanitins; Bucladesine; Calcitriol; Cell Differentiation; Cell Division; Cell Line; Cycloheximide; Dimethyl Sulfoxide; Drug Interactions; Humans; Leucine; Leukemia, Myeloid, Acute; Magnesium Deficiency; Naphthacenes; Oncogenes; Peptide Chain Elongation, Translational; Phenotype; RNA, Messenger; Tetradecanoylphorbol Acetate; Tretinoin | 1987 |
Cannabinoids induce incomplete maturation of cultured human leukemia cells.
Topics: Calcitriol; Cannabidiol; Cannabinoids; Cannabinol; Cell Differentiation; Cells, Cultured; Dronabinol; Humans; Leukemia, Myeloid, Acute; Lymphocyte Activation; Monocytes; Tetradecanoylphorbol Acetate | 1987 |
Cell-free activation of phagocyte NADPH-oxidase: tissue and differentiation-specific expression of cytosolic cofactor activity.
Topics: Animals; Cell Differentiation; Cell Division; Cell Line; Cytosol; Dimethyl Sulfoxide; Enzyme Activation; Erythrocytes; Humans; Leukemia, Myeloid, Acute; Lymphocytes; Mice; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Phagocytes; Superoxides; Tetradecanoylphorbol Acetate; Tissue Distribution | 1987 |
Comparative effects of polymyxin B, phorbol ester and bryostatin on protein phosphorylation, protein kinase C translocation, phospholipid metabolism and differentiation of HL60 cells.
Topics: Bryostatins; Cell Adhesion; Cell Differentiation; Cell Line; Dinoprostone; Humans; Lactones; Leukemia, Myeloid, Acute; Macrolides; Phorbol Esters; Phosphatidylcholines; Phospholipids; Phosphorylation; Polymyxin B; Polymyxins; Prostaglandins E; Protein Kinase C; Proteins; Tetradecanoylphorbol Acetate | 1987 |
Regulation of HLA class II antigen expression: intracellular signaling molecules responsible for the regulation by IFN-gamma and cross-linking of Fc receptors in HL-60 cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Antigens, Neoplasm; Calcimycin; Calcium; Calmodulin; Cell Line; Cyclic AMP; Gene Expression Regulation; Histocompatibility Antigens Class II; Humans; Immunoglobulin G; Interferon-gamma; Isoquinolines; Leukemia, Myeloid, Acute; Male; Middle Aged; Piperazines; Protein Kinase C; Receptors, Fc; Recombinant Proteins; Sulfonamides; Tetradecanoylphorbol Acetate | 1987 |
Chemotactic factor binding and functional capacity: a comparison between human granulocytes and differentiated HL-60 cells.
Topics: Cell Line; Cytoplasmic Granules; Granulocytes; Humans; Leukemia, Myeloid, Acute; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Oxidation-Reduction; Peroxidase; Receptors, Formyl Peptide; Receptors, Immunologic; Tetradecanoylphorbol Acetate | 1987 |
Ribonucleotide reductase M1 subunit in cellular proliferation, quiescence, and differentiation.
Topics: Cell Differentiation; Cell Division; Cell Line; Cell Survival; Humans; Interphase; Leukemia, Myeloid, Acute; Macromolecular Substances; Ribonucleotide Reductases; Tetradecanoylphorbol Acetate | 1988 |
Influence of the poly (ADP-ribose) polymerase inhibitor 3-aminobenzamide on macrophage and granulocyte differentiation of HL-60 cells.
Topics: Acid Phosphatase; Benzamides; Cell Differentiation; Cell Line; Granulocytes; Hematopoietic Stem Cells; Humans; Isoniazid; Leukemia, Myeloid, Acute; Macrophages; Poly(ADP-ribose) Polymerase Inhibitors; Tetradecanoylphorbol Acetate; Tretinoin | 1986 |
c-fos expression is neither sufficient nor obligatory for differentiation of monomyelocytes to macrophages.
Topics: Calcitriol; Cell Differentiation; Cell Line; Cycloheximide; Diglycerides; Gene Expression Regulation; Leukemia, Myeloid, Acute; Macrophages; Monocytes; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate | 1986 |
Expression of Tac antigen on human immature B-cell lineage leukemic cells.
Topics: Antibodies, Monoclonal; Antigens, Surface; B-Lymphocytes; Cell Cycle; Cell Differentiation; Chemical Precipitation; Humans; Interleukin-2; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Molecular Weight; Receptors, Immunologic; Receptors, Interleukin-2; Recombinant Proteins; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1986 |
Lipoxygenation of arachidonic acid by differentiated and undifferentiated human promyelocytic HL-60 cells.
Topics: Arachidonic Acid; Arachidonic Acids; Calcimycin; Cell Differentiation; Cell Line; Chromatography, High Pressure Liquid; Dimethyl Sulfoxide; Humans; Leukemia, Myeloid, Acute; Lipoxygenase; Tetradecanoylphorbol Acetate | 1986 |
Retinoic acid promotes phorbol ester-initiated macrophage differentiation in HL-60 leukemia cells without disappearance of protein kinase C.
Topics: Cell Differentiation; Cell Line; Humans; Leukemia, Myeloid, Acute; Macrophages; Muscle Proteins; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate; Tretinoin; Vinculin | 1986 |
Expression of c-fos protooncogene in normal human peripheral blood granulocytes.
Topics: Cell Differentiation; Cell Line; Colony-Stimulating Factors; Gene Expression Regulation; Glycoproteins; Granulocytes; Humans; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Monocytes; Neoplasm Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1987 |
Synthetic analogues (indolactams) of (-)-indolactam-V are new congeners of the teleocidin class of tumor promoters.
Topics: Animals; Cell Adhesion; Cell Line; Dose-Response Relationship, Drug; Enzyme Induction; Humans; Indoles; Lactams; Leukemia, Myeloid, Acute; Lyngbya Toxins; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Protein Kinase C; Skin; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1987 |
Disparate effects of activators of protein kinase C on HL-60 promyelocytic leukemia cell differentiation.
Topics: Calcimycin; Cell Differentiation; Cell Line; Diglycerides; Diterpenes; Enzyme Activation; Humans; Leukemia, Myeloid, Acute; Protein Kinase C; Terpenes; Tetradecanoylphorbol Acetate | 1987 |
Expression of c-fos in human normal and neoplastic monocyte-macrophage differentiation.
Topics: Calcitriol; Cell Differentiation; Gene Expression Regulation; Humans; Leukemia; Leukemia, Erythroblastic, Acute; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Macrophages; Monocytes; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1987 |
Okadaic acid: an additional non-phorbol-12-tetradecanoate-13-acetate-type tumor promoter.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Enzyme Induction; Ethers, Cyclic; Humans; Leukemia, Myeloid, Acute; Lyngbya Toxins; Mice; Okadaic Acid; Ornithine Decarboxylase; Porifera; Protein Kinase C; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1988 |
Inhibition of the chemotactic peptide-induced elevation of intracellular calcium in differentiated human leukemic (HL-60) cells by the phorbol ester phorbol 12-myristate 13-acetate.
Topics: Calcium; Cell Differentiation; Dose-Response Relationship, Drug; GTP-Binding Proteins; Humans; Inositol Phosphates; Leukemia, Myeloid, Acute; N-Formylmethionine Leucyl-Phenylalanine; Tetradecanoylphorbol Acetate | 1988 |
Role of protein kinase C in phosphorylation of vinculin in adriamycin-resistant HL-60 leukemia cells.
Topics: Cell Differentiation; Doxorubicin; Drug Resistance; Endopeptidases; Humans; Leukemia, Myeloid, Acute; Muscle Proteins; Neprilysin; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vinculin | 1988 |
Clinical application of phorbol diester-induced leukemic cell differentiation for the definite diagnosis of acute leukemias.
Topics: Acute Disease; Adolescent; Adult; Cell Differentiation; Cell Transformation, Neoplastic; Diagnosis, Differential; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Middle Aged; Tetradecanoylphorbol Acetate | 1988 |
Cell-free system studies on the phosphorylation of the 17,000-20,000 dalton protein induced by phorbol ester in human leukemic cells and evidence for a similar event in virally transformed murine fibroblasts.
Topics: Animals; Cell Line; Cell Transformation, Viral; Cell-Free System; Cytosol; Fibroblasts; Humans; Kirsten murine sarcoma virus; Leukemia, Myeloid, Acute; Mice; Molecular Weight; Neoplasm Proteins; Phorbols; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein Kinases; Tetradecanoylphorbol Acetate; Trypsin | 1985 |
Phospholipid- and Ca2+-dependent protein kinase activity and protein phosphorylation patterns in the differentiation of human promyelocytic leukemia cell line HL-60.
Topics: Calcitriol; Cell Differentiation; Dimethyl Sulfoxide; Electrophoresis, Polyacrylamide Gel; Humans; Leukemia, Myeloid, Acute; Macrophages; Neoplasm Proteins; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein Kinases; Tetradecanoylphorbol Acetate; Tretinoin | 1985 |
Evidence of intracellular and trans-acting differentiation-inducing activity in human promyelocytic leukemia HL-60 cells: its possible involvement in process of cell differentiation from a commitment step to a phenotype-expression step.
Topics: Calcitriol; Cell Differentiation; Cell Division; Cell Extracts; Humans; Hybrid Cells; Intracellular Membranes; Leukemia, Myeloid, Acute; Phenotype; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1988 |
Relationship between membrane sterol composition and responsiveness to 12-O-tetradecanoylphorbol 13-acetate in HL-60 human promyelocytic leukaemia cell lines.
Topics: Acetates; Carbon Radioisotopes; Cell Line; Cholesterol; Humans; Lanosterol; Leucine; Leukemia, Myeloid, Acute; Lipid Metabolism; Pyruvates; Pyruvic Acid; Sterols; Tetradecanoylphorbol Acetate; Tritium; Tumor Cells, Cultured | 1988 |
A phorbol ester tolerant (PET) variant of HL-60 promyelocytes.
Topics: Cell Differentiation; Cell Line; Drug Tolerance; Genetic Variation; Karyotyping; Leukemia, Myeloid, Acute; Microscopy, Electron; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured | 1988 |
Protein kinase C activities with different characteristics, including substrate specificity, from two human HL-60 leukemia cell variants.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Calcium; Humans; Isoquinolines; Leukemia, Myeloid, Acute; Lipids; Phosphorylation; Piperazines; Protein Kinase C; Proteins; Substrate Specificity; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1988 |
Temporal changes in intracellular distribution of protein kinase C during differentiation of human leukemia HL60 cells induced by phorbol ester.
Topics: Cell Differentiation; Cell Line; Cell Membrane; Cell Nucleus; Cytoplasm; Humans; Kinetics; Leukemia, Myeloid, Acute; Protein Kinase C; Tetradecanoylphorbol Acetate; Time Factors | 1988 |
Ganglioside GM3 as a modulator of differentiation of mouse myeloid leukemia cells (M1-T22).
Topics: Animals; Cell Differentiation; Dexamethasone; G(M3) Ganglioside; Gangliosides; Globosides; Glycolipids; Humans; Lactosylceramides; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Mice; Phagocytosis; Tetradecanoylphorbol Acetate; Trihexosylceramides; Tumor Cells, Cultured | 1988 |
Phorbol esters inhibit inositol phosphate and diacylglycerol formation in proliferating HL60 cells. Relationship to differentiation.
Topics: Cell Differentiation; Cell Line; Diglycerides; Glycerides; Humans; Inositol Phosphates; Kinetics; Leukemia, Myeloid, Acute; Phorbol Esters; Structure-Activity Relationship; Sugar Phosphates; Tetradecanoylphorbol Acetate | 1988 |
Alterations in histone phosphorylation in HL-60 cells specific to monocytic differentiation.
Topics: Cell Differentiation; Dimethyl Sulfoxide; Histones; Humans; Leukemia, Myeloid, Acute; Monocytes; Phosphorylation; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1988 |
Expression of the platelet-derived growth factor 1 and 2 genes in human myeloid cell lines and monocytes.
Topics: Cell Differentiation; Cycloheximide; Gene Expression Regulation; Humans; Leukemia, Myeloid, Acute; Monocytes; Platelet-Derived Growth Factor; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1988 |
Transferrin receptor and 4F2 expression by NK-sensitive and NK-resistant tumour cell lines.
Topics: Antigens, Surface; Cytotoxicity, Immunologic; Dimethyl Sulfoxide; Fusion Regulatory Protein-1; HLA-DR Antigens; Humans; Killer Cells, Natural; Leukemia, Myeloid, Acute; Receptors, Transferrin; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1988 |
Phorbol ester stimulation of sphingomyelin synthesis in human leukemic HL60 cells.
Topics: Bryostatins; Cell Line; Choline; Diterpenes; Enzyme Activation; Humans; Lactones; Leukemia, Myeloid, Acute; Macrolides; Phosphatidylcholines; Phosphorylation; Protein Kinase C; Sphingomyelins; Terpenes; Tetradecanoylphorbol Acetate | 1988 |
[Changes in the expression and structure of some proto-oncogenes in TPA-induced HL-60 and Raji cells].
Topics: Burkitt Lymphoma; Gene Expression Regulation; Humans; Leukemia, Myeloid, Acute; Proto-Oncogenes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1988 |
In vitro induction of myeloid surface markers in a rare case of acute leukemia.
Topics: Acute Disease; Aged; Antibodies, Monoclonal; Antigens, Neoplasm; Antigens, Surface; Blast Crisis; Cells, Cultured; Flow Cytometry; Fluorescent Antibody Technique; Humans; Hybridization, Genetic; Leukemia; Leukemia, Myeloid, Acute; Lewis X Antigen; Lymphocytes; Male; Neuraminidase; Phenotype; Tetradecanoylphorbol Acetate | 1987 |
Adenosine deaminase mRNA expression is regulated posttranscriptionally during differentiation of HL-60 cells.
Topics: Adenosine Deaminase; Cell Differentiation; Cell Line; Dimethyl Sulfoxide; Enzyme Induction; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Monocytes; Neoplasm Proteins; Nucleoside Deaminases; Protein Biosynthesis; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myc; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate | 1987 |
Bryostatin induces changes in protein kinase C location and activity without altering c-myc gene expression in human promyelocytic leukemia cells (HL-60).
Topics: Bryostatins; Cell Compartmentation; Cell Membrane; Cytoplasm; Gene Expression Regulation; Humans; Lactones; Leukemia, Myeloid, Acute; Macrolides; Phosphorylation; Protein Kinase C; Proto-Oncogene Proteins; Receptors, Transferrin; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1987 |
Dioctanoylglycerol and phorbol esters regulate transcription of c-myc in human promyelocytic leukemia cells.
Topics: Diglycerides; Enzyme Activation; Glycerides; Humans; Leukemia, Myeloid, Acute; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Proto-Oncogenes; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 1988 |
Cell differentiation and cell cycle effects on human promyelocytic leukemia cells induced by 12-O-tetradecanoylphorbol-13-acetate.
Topics: Cell Cycle; Cell Differentiation; Cell Line; Flow Cytometry; Histocytochemistry; Humans; Isoenzymes; L-Lactate Dehydrogenase; Leukemia, Myeloid, Acute; Mitosis; Nitroblue Tetrazolium; Oxidation-Reduction; Phagocytosis; Phenotype; Phorbols; Receptors, Fc; Tetradecanoylphorbol Acetate | 1986 |
Phorbol diester-induced phosphorylation of nuclear matrix proteins in HL60 promyelocytes. Possible role in differentiation studied by cationic detergent gel electrophoresis.
Topics: Antigens, Nuclear; Autoantibodies; Autoradiography; Cell Adhesion; Cell Line; Electrophoresis, Polyacrylamide Gel; Humans; Kinetics; Leukemia, Myeloid, Acute; Nucleoproteins; Phorbols; Phosphorus Radioisotopes; Phosphorylation; Tetradecanoylphorbol Acetate | 1986 |
Effects of selenium compounds on phospholipid/Ca2+-dependent protein kinase (protein kinase C) system from human leukemic cells.
Topics: Animals; Calcium; Humans; Kinetics; Leukemia, Myeloid, Acute; Lysophospholipids; Myocardium; Phosphatidylserines; Phospholipids; Protein Kinase C; Selenium; Swine; Tamoxifen; Tetradecanoylphorbol Acetate | 1986 |
Cathepsin B synthesis by the HL60 promyelocytic cell line: effects of stimulating agents and anti-inflammatory compounds.
Topics: Anti-Inflammatory Agents; Butanones; Carboxylesterase; Carboxylic Ester Hydrolases; Carrageenan; Cathepsin B; Cathepsins; Cell Differentiation; Cell Line; Dexamethasone; Endotoxins; Humans; Indomethacin; Leukemia, Myeloid, Acute; Macrophages; Monocytes; Nabumetone; Phagocytosis; Tetradecanoylphorbol Acetate | 1986 |
Inability of HL-60 cells induced by phorbol myristate acetate to produce macrophage-associated glycosaminoglycans.
Topics: Cell Line; Glycosaminoglycans; Humans; Kinetics; Leukemia, Myeloid, Acute; Macrophages; Phorbols; Sulfur Radioisotopes; Tetradecanoylphorbol Acetate | 1986 |
Electron microscopic and immunohistochemical observations of differentiation of human myeloid leukemia line, PL-21.
Topics: Cell Differentiation; Cell Line; Histocytochemistry; Humans; Leukemia, Myeloid, Acute; Microscopy, Electron; Nitroblue Tetrazolium; Phagocytosis; S100 Proteins; Tetradecanoylphorbol Acetate; Tretinoin | 1986 |
Dimethylsulfoxide, retinoic acid and 12-O-tetradecanoylphorbol-13-acetate induce a selective decrease in the phosphorylation of P150, a surface membrane phosphoprotein of HL60 cells resistant to adriamycin.
Topics: Dimethyl Sulfoxide; Doxorubicin; Drug Resistance; Electrophoresis, Polyacrylamide Gel; Humans; Leukemia, Myeloid, Acute; Membrane Proteins; Phorbols; Phosphoproteins; Phosphorylation; Protein Kinases; Tetradecanoylphorbol Acetate; Tretinoin | 1986 |
Induction of differentiation in HL-60 promyelocytic cells: a comparative study in two sublines.
Topics: Antibodies, Monoclonal; Antibodies, Neoplasm; Antigens, Neoplasm; Antigens, Surface; Cell Differentiation; Cell Line; Humans; Leukemia, Myeloid, Acute; Lymphocyte Activation; Lymphokines; Male; Tetradecanoylphorbol Acetate; Tretinoin | 1986 |
Inhibition of phorbol ester-dependent differentiation of human promyelocytic leukemic (HL-60) cells by sphinganine and other long-chain bases.
Topics: Acid Phosphatase; Binding, Competitive; Cell Adhesion; Cell Differentiation; Cell Line; Humans; Kinetics; Leukemia, Myeloid, Acute; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Sphingosine; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1986 |
1-(5-Isoquinolinesulfonyl)-2-methylpiperazine(H-7), a potent inhibitor of protein kinases, inhibits the differentiation of HL-60 cells induced by phorbol diester.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Cell Differentiation; Cell Division; Cell Line; Depression, Chemical; Humans; Isoquinolines; Leukemia, Myeloid, Acute; Male; Phosphorylation; Piperazines; Protein Kinase C; Sulfonamides; Tetradecanoylphorbol Acetate | 1986 |
Identification and characterization of the nonphosphorylated precursor of pp17, a phosphoprotein associated with phorbol ester induction of growth arrest and monocytic differentiation in HL-60 promyelocytic leukemia cells.
Topics: Carrier Proteins; Cell Differentiation; Cell Division; Cell Line; DNA-Binding Proteins; Electrophoresis, Polyacrylamide Gel; Humans; Intracellular Signaling Peptides and Proteins; Leukemia, Myeloid, Acute; Molecular Weight; Perilipin-3; Phosphorylation; Pregnancy Proteins; Protein Precursors; Tetradecanoylphorbol Acetate; Vesicular Transport Proteins | 1986 |
Role of intracellular calcium ion in human promyelocytic leukemia HL-60 cell differentiation.
Topics: Calcitriol; Calcium; Cell Differentiation; Cell Division; Cell Line; Dimethyl Sulfoxide; Ethers; Gallic Acid; Humans; Ionomycin; Leukemia, Myeloid, Acute; Tetradecanoylphorbol Acetate; Tretinoin; Verapamil | 1986 |
Activation of CMP-N-acetylneuraminic acid:lactosylceramide sialyltransferase during the differentiation of HL-60 cells induced by 12-O-tetradecanoylphorbol-13-acetate.
Topics: Calcitriol; Cell Differentiation; Cell Line; Enzyme Activation; G(M3) Ganglioside; Humans; Leukemia, Myeloid, Acute; Phorbol Esters; Phosphorylation; Sialyltransferases; Substrate Specificity; Tetradecanoylphorbol Acetate | 1986 |
Differential effects of various protein kinase C activators on protein phosphorylation in human acute myeloblastic leukemia cell line KG-1 and its phorbol ester-resistant subline KG-1a.
Topics: Bryostatins; Cell Differentiation; Cell Line; Diglycerides; Diterpenes; Drug Resistance; Enzyme Activation; Humans; Lactones; Leukemia, Myeloid, Acute; Macrolides; Phosphorylation; Protein Kinase C; Proteins; Pyrimidinones; Terpenes; Tetradecanoylphorbol Acetate; Thiazoles | 1987 |
Retinoic acid-induced monocytic differentiation of HL60/MRI, a cell line derived from a transplantable HL60 tumor.
Topics: Acetamides; Animals; Antigens, Surface; Cell Differentiation; Cell Line; Chromosome Aberrations; Dimethyl Sulfoxide; Humans; Isoenzymes; Leukemia, Myeloid, Acute; Mice; Mice, Inbred BALB C; Monocytes; Neoplasm Transplantation; Tetradecanoylphorbol Acetate; Tretinoin | 1987 |
12-O-tetradecanoyl phorbol 13-acetate stimulates the myristylation of an approximately 82 kDa protein in HL-60 cells.
Topics: Acylation; Cell Differentiation; Cell Line; Humans; Leukemia, Myeloid, Acute; Lipid Metabolism; Male; Molecular Weight; Myristic Acid; Myristic Acids; Neoplasm Proteins; Tetradecanoylphorbol Acetate | 1987 |
Modes of inhibitory action of protein kinase C in the chemotactic peptide-induced formation of inositol phosphates in differentiated human leukemic (HL-60) cells.
Topics: 2,3-Diphosphoglycerate; Calcium; Cell Differentiation; Cell Line; Cell Membrane; Diphosphoglyceric Acids; Guanosine Triphosphate; Humans; Inositol Phosphates; Kinetics; Leukemia, Myeloid, Acute; Membrane Lipids; N-Formylmethionine Leucyl-Phenylalanine; Protein Kinase C; Sugar Phosphates; Tetradecanoylphorbol Acetate | 1987 |
Inhibition of growth but not differentiation of normal and leukemic myeloid cells by methylthioadenosine.
Topics: Adenosine; Cell Differentiation; Cell Division; Cell Line; Colony-Forming Units Assay; Deoxyadenosines; Granulocytes; Humans; Leukemia, Myeloid, Acute; Macrophages; Spermidine; Spermine; Tetradecanoylphorbol Acetate; Thionucleosides | 1987 |
Differentiation-associated carbohydrate chain on human hematopoietic cells recognized by Clerodendron trichotomum lectin.
Topics: Carbohydrate Metabolism; Cell Differentiation; Cell Line; Erythrocytes; Hematopoietic Stem Cells; Humans; Lectins; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Neoplastic Stem Cells; Plant Lectins; Receptors, Mitogen; Tetradecanoylphorbol Acetate | 1987 |
1,25-Dihydroxyvitamin D3 and phorbol esters (TPA) may induce select in vitro differentiation pathways in the HL60 promyelocytic cell line.
Topics: Antigens, Neoplasm; Calcitriol; Cell Differentiation; Cell Line; HLA-DQ Antigens; HLA-DR Antigens; Humans; Leukemia, Myeloid, Acute; Male; Monocytes; Receptors, Fc; Tetradecanoylphorbol Acetate | 1987 |
Effect of two inducers of cellular differentiation on the glutathione status of human HL-60 promyelocytic leukaemia and A549 lung carcinoma cells.
Topics: Animals; Carcinoma; Cell Differentiation; Cell Line; Dimethyl Sulfoxide; Formamides; Glutathione; Humans; Leukemia, Myeloid, Acute; Lung Neoplasms; Mice; Neoplasms, Experimental; Tetradecanoylphorbol Acetate | 1987 |
Bone marrow matrix modulation of HL-60 phenotype.
Topics: Bone Marrow; Bone Matrix; Cell Adhesion; Cell Division; Cell Line; Cell Survival; Culture Media; Extracellular Matrix; Fibroblasts; Humans; Leukemia, Myeloid, Acute; Male; Phenotype; Tetradecanoylphorbol Acetate | 1987 |
Effects of phorbol ester on translocation and down-regulation of protein kinase C and phosphorylation of endogenous proteins in human acute myeloid leukemia cell line KG-1 and its phorbol ester-resistant subline KG-1a.
Topics: Biological Transport; Cell Adhesion; Cell Line; Drug Resistance; Humans; Immunohistochemistry; Leukemia, Myeloid, Acute; Molecular Weight; Phosphorylation; Protein Kinase C; Subcellular Fractions; Tetradecanoylphorbol Acetate | 1987 |
Hairy cell leukaemia: effects of phorbol ester on cell morphology and adherence and comparison with other B-cell neoplasias.
Topics: B-Lymphocytes; Cell Adhesion; Humans; Leukemia, Hairy Cell; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma; Microscopy, Electron; Microscopy, Electron, Scanning; Phorbols; Tetradecanoylphorbol Acetate | 1986 |
Induction of colony-stimulating factor response in myeloid leukaemia cell lines.
Topics: Calcitriol; Cell Differentiation; Cell Division; Cell Line; Colony-Stimulating Factors; Dimethyl Sulfoxide; Humans; Interleukin-3; Leukemia, Myeloid, Acute; Macrophages; Tetradecanoylphorbol Acetate | 1986 |
Occurrence of particular isoenzymes in fresh and cultured leukemia-lymphoma cells. III. Esterase isoenzyme in monocytes.
Topics: B-Lymphocytes; Carboxylic Ester Hydrolases; Cell Differentiation; Cell Line; Enzyme Activation; Humans; Isoenzymes; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lymphoma; Monocytes; Naphthol AS D Esterase; Tetradecanoylphorbol Acetate | 1987 |
Differential effects of phorbol esters on normal myeloid precursors and leukemic cells: basis for autologous bone marrow reconstitution in acute nonlymphocytic leukemia using phorbol ester-treated bone marrow from patients in remission.
Topics: Bone Marrow; Bone Marrow Cells; Bone Marrow Transplantation; Cell Cycle; Cell Differentiation; Cells, Cultured; Colony-Forming Units Assay; Combined Modality Therapy; Dose-Response Relationship, Drug; Freezing; Hematopoiesis; Humans; Karyotyping; Leukemia; Leukemia, Myeloid, Acute; Phorbols; Preservation, Biological; Tetradecanoylphorbol Acetate; Time Factors | 1986 |
Induction of c-sis gene expression and synthesis of platelet-derived growth factor in human myeloid leukemia cells during monocytic differentiation.
Topics: Cell Cycle; Cell Differentiation; Cell Line; Cycloheximide; Gene Expression Regulation; Humans; Leukemia, Myeloid, Acute; Macrophages; Monocytes; Platelet-Derived Growth Factor; Proto-Oncogene Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate | 1986 |
Reassembly of c-myc and relaxation of c-fos nucleosomes during differentiation of human leukemic (HL-60) cells.
Topics: Cell Differentiation; Gene Expression Regulation; Humans; Leukemia, Myeloid, Acute; Nucleosomes; Protamines; Proto-Oncogene Proteins; Proto-Oncogenes; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1986 |
Dissociation of c-fos induction from macrophage differentiation in human myeloid leukemic cell lines.
Topics: Cell Differentiation; Cell Line; Diglycerides; Gene Expression Regulation; Humans; Leukemia, Myeloid, Acute; Macrophages; Protein Kinase C; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogenes; Retinaldehyde; Tetradecanoylphorbol Acetate | 1987 |
Regulation of glycophorin gene expression by a tumor-promoting phorbol ester in human leukemic K562 cells.
Topics: Cell Line; Genes; Glucosamine; Glycophorins; Humans; Kinetics; Leukemia, Myeloid, Acute; Methionine; Molecular Weight; Phorbols; Sialoglycoproteins; Sulfur Radioisotopes; Tetradecanoylphorbol Acetate; Tritium | 1985 |
Human c-myc and N-ras expression during induction of HL-60 cellular differentiation.
Topics: Acetamides; Calcitriol; Carcinogens; Cell Differentiation; Cell Line; Dimethyl Sulfoxide; Gene Expression Regulation; Humans; Leukemia, Myeloid, Acute; Oncogenes; RNA, Neoplasm; Tetradecanoylphorbol Acetate | 1985 |
A new myelomonoblastic cell line (M20): analysis of properties, differentiation, and comparison with other established lines of similar origin.
Topics: Animals; Cell Adhesion; Cell Differentiation; Cell Line; Child; Cytoplasm; Dimethyl Sulfoxide; Granulocytes; Humans; Leukemia, Experimental; Leukemia, Myeloid, Acute; Microscopy, Electron, Scanning; Phagocytosis; Receptors, Antigen, B-Cell; Receptors, Fc; Tetradecanoylphorbol Acetate | 1985 |
Control of lysozyme gene expression in differentiating HL-60 cells.
Topics: Animals; Cell Differentiation; Cell Line; Gene Expression Regulation; Humans; Leukemia, Experimental; Leukemia, Myeloid, Acute; Macrophages; Muramidase; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors | 1985 |
Recombinant human interferon sensitizes resistant myeloid leukemic cells to induction of terminal differentiation.
Topics: Cell Differentiation; Cell Division; Cell Line; Dimethyl Sulfoxide; Drug Synergism; Humans; Interferon Type I; Leukemia, Myeloid, Acute; Tetradecanoylphorbol Acetate; Tretinoin | 1985 |
Specific protein phosphorylation in human promyelocytic HL-60 leukemia cells susceptible or resistant to induction of cell differentiation by phorbol-12-myristate-13-acetate.
Topics: Caenorhabditis elegans Proteins; Carrier Proteins; Cell Differentiation; Cell Line; Drug Resistance; Humans; Leukemia, Myeloid, Acute; Molecular Weight; Neoplasm Proteins; Phorbols; Phosphoproteins; Phosphorylation; Protein Kinase C; Receptors, Drug; Receptors, Immunologic; Tetradecanoylphorbol Acetate | 1985 |
Chromatin structure of the c-myc gene in HL-60 cells during alterations of transcriptional activity.
Topics: Cell Line; Chromatin; Dimethyl Sulfoxide; DNA; Humans; Leukemia, Myeloid, Acute; Methylation; Oncogenes; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1985 |
Characterization of differentiation-inducer-resistant HL-60 cells.
Topics: Bromodeoxyuridine; Butyrates; Butyric Acid; Cell Count; Cell Differentiation; Cell Division; Cell Line; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Drug Resistance; Gene Amplification; Humans; Hypoxanthine; Hypoxanthines; Leukemia, Myeloid, Acute; Oncogenes; Ouabain; Phenotype; Tetradecanoylphorbol Acetate; Thioguanine; Tretinoin | 1985 |
Multiplication of human fetal myelomonocytic precursors in medium conditioned by acute myelocytic leukemia cells treated by 12-O-tetradecanoyl phorbol 13-acetate (TPA).
Topics: Bone Marrow; Bone Marrow Cells; Cell Division; Colony-Forming Units Assay; Culture Media; Culture Techniques; Fetus; Granulocytes; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid, Acute; Macrophages; Phorbols; Tetradecanoylphorbol Acetate | 1985 |
Cytochemical examinations of cultivated unclassified leukaemic cells.
Topics: Acute Disease; Cell Differentiation; Cell Division; Cells, Cultured; Esterases; Histocytochemistry; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Tetradecanoylphorbol Acetate | 1985 |
Induction of differentiation of HL-60 cells by different agents and the phospholipid-sensitive Ca++ dependent protein phosphorylation system.
Topics: Calcitriol; Cell Differentiation; Cell Line; Dimethyl Sulfoxide; Humans; Leukemia, Myeloid, Acute; Neoplasm Proteins; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate; Tretinoin | 1985 |
Growth of human bone marrow in vitro.
Topics: Bone Marrow Cells; Cell Division; Cells, Cultured; Colony-Stimulating Factors; Culture Media; Hematopoiesis; Humans; Leukemia, Myeloid, Acute; Macrophages; Monocytes; Phorbols; Tetradecanoylphorbol Acetate | 1985 |
Chemotactic peptide activation of human neutrophils and HL-60 cells. Pertussis toxin reveals correlation between inositol trisphosphate generation, calcium ion transients, and cellular activation.
Topics: Calcium; Cell Line; Cytoplasmic Granules; Ethers; Guanosine Triphosphate; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Intracellular Fluid; Ionomycin; Leukemia, Myeloid, Acute; Lymphocyte Activation; Membrane Potentials; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Tetradecanoylphorbol Acetate; Type C Phospholipases; Virulence Factors, Bordetella | 1985 |
Rapid induction of the expression of proto-oncogene fos during human monocytic differentiation.
Topics: Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; Dimethyl Sulfoxide; Fluorescent Antibody Technique; Genes; Humans; Leukemia, Myeloid, Acute; Macrophages; Neoplasm Proteins; Oncogenes; Protein Biosynthesis; Proto-Oncogene Mas; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1985 |
Macrophage glycolipid receptors for human migration inhibitory factor (MIF): differentiated HL-60 cells exhibit MIF responsiveness and express surface glycolipids which both bind MIF and convert nonresponsive cells to responsiveness.
Topics: Cell Differentiation; Cell Line; Glycolipids; Humans; Leukemia, Myeloid, Acute; Leukocyte Migration-Inhibitory Factors; Lymphocytes; Macrophages; Receptors, Immunologic; Tetradecanoylphorbol Acetate | 1985 |
Phorbol ester effect in platelets, lymphocytes, and leukemic cells (HL-60) is associated with enhanced phosphorylation of class I HLA antigens. Coprecipitation of myosin light chain.
Topics: Blood Platelets; Cell Line; Electrophoresis, Polyacrylamide Gel; HLA Antigens; Humans; Immunosorbent Techniques; Leukemia, Myeloid, Acute; Lymphocytes; Phorbols; Phosphorylation; Tetradecanoylphorbol Acetate | 1985 |
Variables that regulate production of insulin-like peptide(s) in human leukemia cell line (HL-60).
Topics: Calcitriol; Cell Count; Cell Differentiation; Cell Line; Dose-Response Relationship, Drug; Glucose; Humans; Insulin; Leukemia, Myeloid, Acute; Peptide Biosynthesis; Peptides; Somatomedins; Tetradecanoylphorbol Acetate | 1985 |