Compounds > tetradecanoylphorbol acetate
Page last updated: 2024-08-23

tetradecanoylphorbol acetate and Abnormalities, Autosome

tetradecanoylphorbol acetate has been researched along with Abnormalities, Autosome in 66 studies

Research

Studies (66)

TimeframeStudies, this research(%)All Research%
pre-199038 (57.58)18.7374
1990's20 (30.30)18.2507
2000's5 (7.58)29.6817
2010's3 (4.55)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lau, LC; Lee, GY; Liaw, FP; Lim, AS; Lim, TH; Tien, SL1
Bajaj, R; Gong, JZ; Holmes, PJ; Peiper, SC; Uppal, GK; Wang, ZX1
Audhuy, B; Gervais, C; Helias, C; Herbrecht, R; Mauvieux, L; Struski, S1
Andritsos, L; Breidenbach, H; Byrd, JC; Flynn, J; Heerema, NA; Jarjoura, D; Jones, J; Mo, X; Muthusamy, N; Ramanunni, A1
Blasco, MA; Cayuela, ML; Flores, JM1
Abdel-Rahman, SZ; Albrecht, T; Deng, CZ; El-Zein, RA; Fons, MP; Rosenblatt, J1
Aventín, A; Sánchez, J1
Fürstenberger, G; Kittstein, W; Kunz, W; Marks, F; Peres, G; Schwarz, M1
Ros, Y1
Dewdney, RS; Soper, CJ1
Au, WW; Callaham, MF; Huberman, E; Workman, ML1
Han, T; Matsui, S; Sadamori, N; Sandberg, AA1
Cerutti, P; Emerit, I1
Gainer, HS; Kinsella, AR2
Fusenig, NE1
Kokunai, T; Matsumoto, S; Tamaki, N1
Cerutti, PA; Emerit, I1
Callen, DF; Ford, JH1
Kinsella, AR; Radman, M2
Dzarlieva, RT; Fusenig, NE1
Grotte, G; Påhlman, S1
Chau, WK; Chiu, CF; Lin, CK; Lin, FM; Liu, SM; Tan, TD1
Allen, S; Brody, JP; Chan, WC; Cone, RW; Friedman, HD; Koduru, P; Loughran, TP; Schulman, P; Sun, T; Teichberg, S1
Balmain, A; Bremner, R; Kemp, CJ1
Rosin, MP; Ward, AJ1
Asada, H; Hashimoto, K; Hirota, S; Kitamura, Y; Nomura, S; Okada, N; Sairenji, T; Yamanishi, K; Yoshikawa, K1
Adachi, N; Horiuchi, S; Matsuda, I; Naito, M; Nakamura, R; Ohta, T; Takaki, K1
Rao, KP; Sridevi, K1
Haesen, S; Kirsch-Volders, M; Timmermans, M1
Cohen, RJ; Gazitt, Y; He, YJ; Shults, K; Stelzer, GT1
deGraffenried, LA; Qin, Q; Rice, RH; Schlegel, R; Steinmann, KE; Taylor, N1
Drexler, HG; Hu, ZB; Ma, W; MacLeod, R; Quentmeier, H; Zaborski, M1
Jordan, R; Schwartz, JL1
Durnev, AD; Guseva, NV; Lisitsina, TA; Nasonova, VA; Pleskovskaia, GN; Seredenin, SB1
Hurme, M; Knuutila, S; Larramendy, ML; Siitonen, SM; Vilpo, JA; Vilpo, L; Zhu, Y1
Goto, K; Haji, M; Ichino, I; Kashimura, Y; Mu, Y; Mukasa, C; Nawata, H; Nishi, Y; Nomura, M; Oba, K; Okabe, T; Saito, M; Takayanagi, R; Yanase, T1
Little, JB; Nagasawa, H1
Latt, SA; Loveday, KS1
Kennedy, AR; Little, JB; Nagasawa, H1
Albino, AP; Houghton, AN; Jhanwar, SC; Nanus, DM; Sozzi, G1
Knuutila, S; Larramendy, ML; Peltomäki, P; Salonen, E1
Fukushima, T; Kawamura, K; Maruyama, K; Mochizuki, S1
Färber, B; Kinzel, V1
Baharav, E; Friedman, J; Halbrecht, I; Sandowski, U; Shabtai, F1
Färber, B; Fusenig, N; Kinzel, V; Petrusevska, RT1
Aldaz, CM; Conti, CJ1
Fürstenberger, G; Fusenig, NE; Kaina, B; Marks, F; Petrusevska, RT; Schurich, B1
Bonne, C; Dornand, J; Emerit, I; Giroud, JP; Griswold, DE; Latour, E; Modat, G; Muller, A; Roch, M; Tissie, G1
Färber, B; Fusenig, NE; Kinzel, V; Petrusevska, RT1
Hoijer, J; Khoobyarian, N; Marczynska, B; Nelson, RL; Spragia, L; Wilson, W1
Stich, HF; Tsang, SS1
Cerutti, PA; Emerit, I; Khan, SH1
Cerutti, P; Emerit, I; Jörg, A; Kozumbo, WJ; Muehlematter, D1
Kramer, IM; Roos, D; van der Bend, RL; Verhoeven, AJ; Weening, RS1
Abe, T; Hashimoto, T; Inoue, R; Kanayama, Y; Machii, T; Ogawa, H; Sugiyama, H; Taniwaki, M; Tokumine, Y; Ueda, E1
Breitman, TR; Imaizumi, M; Uozumi, J1
Davis, MB; Delhanty, JD; Mazzullo, HA; Rider, SH1
Ross, FM; Stockdill, G1
Cosmidis, H; Delinassios, JG; Goula, I; Kokkinopoulos, D; Kottaridis, S; Pangalis, GA; Papamichail, M; Perez, S1
Ross, DW1
Arthur, DC; Kersey, JH; Korsmeyer, SJ; Parkin, JL; Stong, RC1
Emerit, I; Khan, SH1
Dzarlieva-Petrusevska, RT; Fusenig, NE1
DiPaolo, JA1

Reviews

4 review(s) available for tetradecanoylphorbol acetate and Abnormalities, Autosome

ArticleYear
Chromosomal events in carcinogenic initiation and promotion: implications for carcinogenicity testing and cancer prevention strategies.
    IARC scientific publications, 1980, Issue:27

    Topics: Animals; Carcinogens; Cells, Cultured; Chromosome Aberrations; Chromosome Disorders; Chromosomes; Epistasis, Genetic; Genetic Diseases, Inborn; Humans; Methylnitronitrosoguanidine; Mutation; Skin; Tetradecanoylphorbol Acetate; Thioguanine; Time Factors

1980
Phenotypic and chromosomal alterations in cell cultures as indicators of tumor-promoting activity.
    Carcinogenesis; a comprehensive survey, 1982, Volume: 7

    Topics: Animals; Carcinogens; Cell Adhesion; Cell Communication; Cell Differentiation; Cell Division; Cell Membrane; Cell Transformation, Neoplastic; Cells, Cultured; Chromosome Aberrations; Cocarcinogenesis; Fibronectins; Humans; Neoplasms, Experimental; Ornithine Decarboxylase; Plasminogen Activators; Tetradecanoylphorbol Acetate; Tretinoin

1982
The premalignant nature of mouse skin papillomas: histopathologic, cytogenetic, and biochemical evidence.
    Carcinogenesis; a comprehensive survey, 1989, Volume: 11

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biomarkers, Tumor; Cell Transformation, Neoplastic; Chromosome Aberrations; Chromosome Disorders; Karyotyping; Keratins; Mice; Papilloma; Precancerous Conditions; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors

1989
Leukemic cell maturation.
    Archives of pathology & laboratory medicine, 1985, Volume: 109, Issue:4

    Topics: Cell Differentiation; Cell Line; Chromosome Aberrations; Chromosome Disorders; Cytarabine; Dimethyl Sulfoxide; Genotype; Hematopoietic Stem Cells; Humans; Leukemia; Leukemia, Myeloid, Acute; Neoplastic Stem Cells; Neutrophils; Oncogenes; Phenotype; Tetradecanoylphorbol Acetate; Vitamin A

1985

Other Studies

62 other study(ies) available for tetradecanoylphorbol acetate and Abnormalities, Autosome

ArticleYear
CpG Oligonucleotide and Interleukin 2 stimulation enables higher cytogenetic abnormality detection rates than 12-o-tetradecanolyphorbol-13-acetate in Asian patients with B-cell chronic lymphocytic leukemia (B-CLL).
    International journal of hematology, 2014, Volume: 100, Issue:6

    Topics: Aged; Asian People; Chromosome Aberrations; Cytogenetics; Female; Humans; In Situ Hybridization, Fluorescence; Interleukin-2; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Oligodeoxyribonucleotides; Sensitivity and Specificity; Tetradecanoylphorbol Acetate

2014
Efficacy of DSP30-IL2/TPA for detection of cytogenetic abnormalities in chronic lymphocytic leukaemia/small lymphocytic lymphoma.
    International journal of laboratory hematology, 2016, Volume: 38, Issue:5

    Topics: Chromosome Aberrations; Female; Humans; In Situ Hybridization, Fluorescence; Interleukin-2; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Oligonucleotides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

2016
Stimulation of B-cell lymphoproliferations with CpG-oligonucleotide DSP30 plus IL-2 is more effective than with TPA to detect clonal abnormalities.
    Leukemia, 2009, Volume: 23, Issue:3

    Topics: B-Lymphocytes; Cell Division; Cells, Cultured; Chromosome Aberrations; Chromosome Banding; Cohort Studies; Female; Humans; In Situ Hybridization, Fluorescence; Interleukin-2; Karyotyping; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocyte Activation; Lymphoma, B-Cell; Lymphoproliferative Disorders; Male; Metaphase; Mitogens; Oligonucleotides; Tetradecanoylphorbol Acetate

2009
Enhanced detection of chromosomal abnormalities in chronic lymphocytic leukemia by conventional cytogenetics using CpG oligonucleotide in combination with pokeweed mitogen and phorbol myristate acetate.
    Cancer genetics, 2011, Volume: 204, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Chromosome Aberrations; Humans; Karyotyping; Leukemia, Lymphocytic, Chronic, B-Cell; Middle Aged; Oligodeoxyribonucleotides; Pokeweed Mitogens; Sensitivity and Specificity; Tetradecanoylphorbol Acetate

2011
The telomerase RNA component Terc is required for the tumour-promoting effects of Tert overexpression.
    EMBO reports, 2005, Volume: 6, Issue:3

    Topics: Animals; Cell Transformation, Neoplastic; Chromosomal Instability; Chromosome Aberrations; DNA-Binding Proteins; Gene Deletion; In Situ Hybridization, Fluorescence; Keratinocytes; Mice; Mice, Knockout; Mutation; Neoplasms; Protein Subunits; RNA; Skin Neoplasms; Telomerase; Tetradecanoylphorbol Acetate; Wound Healing

2005
Nickel potentiates the genotoxic effect of benzo[a]pyrene in Chinese hamster lung V79 cells.
    Environmental and molecular mutagenesis, 2006, Volume: 47, Issue:3

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Cell Line; Chromium; Chromosome Aberrations; Chromosomes; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Drug Synergism; Male; Microsomes, Liver; Models, Statistical; Nickel; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate; Time Factors

2006
Detection of chromosomal abnormalities in chronic lymphocytic leukemia increased by interphase fluorescence in situ hybridization in tetradecanoylphorbol acetate-stimulated peripheral blood cells.
    Cancer genetics and cytogenetics, 2007, Volume: 175, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Chromosome Aberrations; Female; Humans; In Situ Hybridization, Fluorescence; Interphase; Leukemia, Lymphocytic, Chronic, B-Cell; Leukocytes, Mononuclear; Lymphocyte Count; Male; Middle Aged; Reproducibility of Results; Tetradecanoylphorbol Acetate

2007
On the role of superoxide anion radicals in skin tumour promotion.
    Carcinogenesis, 1984, Volume: 5, Issue:12

    Topics: Animals; Cells, Cultured; Chromosome Aberrations; DNA; Female; Free Radicals; Leukocytes; Mice; Mice, Inbred Strains; Salicylates; Skin Neoplasms; Superoxides; Tetradecanoylphorbol Acetate

1984
[Use of in-vitro treated human blood cells for the detection of the potential genotoxicity of chemical agents].
    Archives belges = Belgisch archief, 1984, Volume: 42, Issue:5-6

    Topics: Acrylamides; Benzopyrenes; Carcinogens; Chromosome Aberrations; Cyclophosphamide; Ethyl Methanesulfonate; Humans; Lymphocyte Activation; Mitomycin; Mitomycins; Mutagens; Tetradecanoylphorbol Acetate

1984
A mutagenesis-enhancing activity of 12-O-tetradecanoylphorbol 13-acetate detected in Chinese hamster ovary cells.
    Mutation research, 1984, Volume: 129, Issue:1

    Topics: Animals; Cells, Cultured; Chromosome Aberrations; Cricetinae; Cricetulus; Drug Synergism; Ethyl Methanesulfonate; Female; Methylnitronitrosoguanidine; Mutation; Ovary; Phorbols; Sister Chromatid Exchange; Tetradecanoylphorbol Acetate; Ultraviolet Rays

1984
Double minute chromatin bodies and other chromosome alterations in human myeloid HL-60 leukemia cells susceptible or resistant to induction of differentiation by phorbol-12-myristate-13-acetate.
    Cancer research, 1983, Volume: 43, Issue:12 Pt 1

    Topics: Cell Differentiation; Cell Line; Chromatin; Chromosome Aberrations; Chromosome Banding; Chromosome Disorders; Drug Resistance; Humans; Karyotyping; Leukemia, Myeloid, Acute; Muramidase; Phorbols; Tetradecanoylphorbol Acetate

1983
Comparative results with various polyclonal B-cell activators in aneuploid chronic lymphocytic leukemia.
    Cancer genetics and cytogenetics, 1984, Volume: 11, Issue:1

    Topics: Aged; Aneuploidy; B-Lymphocytes; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, 6-12 and X; Humans; Karyotyping; Leukemia, Lymphoid; Lymphocyte Activation; Male; Middle Aged; Mitogens; Mitotic Index; Tetradecanoylphorbol Acetate; Trisomy

1984
Clastogenic action of tumor promoter phorbol-12-myristate-13 acetate in mixed human leukocyte cultures.
    Carcinogenesis, 1983, Volume: 4, Issue:10

    Topics: Blood Platelets; Cells, Cultured; Chromosome Aberrations; Culture Media; Humans; Leukocytes; Lymphocytes; Monocytes; Mutagens; Neutrophils; Phorbols; Tetradecanoylphorbol Acetate

1983
Analysis of spontaneous, carcinogen-induced and promoter-induced chromosomal instability in patients with hereditary retinoblastoma.
    International journal of cancer, 1983, Oct-15, Volume: 32, Issue:4

    Topics: Cells, Cultured; Chromosome Aberrations; Chromosome Deletion; Eye Neoplasms; Humans; Methylnitronitrosoguanidine; Ploidies; Retinoblastoma; Sister Chromatid Exchange; Skin; Tetradecanoylphorbol Acetate; Time Factors

1983
Malignant transformation of epithelial cells in culture.
    Progress in clinical and biological research, 1983, Volume: 132B

    Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Chromosome Aberrations; Epithelium; Humans; Mice; Skin; Tetradecanoylphorbol Acetate

1983
In vitro studies of the possible mechanisms whereby tumour promoters mediate their responses.
    Princess Takamatsu symposia, 1983, Volume: 14

    Topics: Carcinogens; Cell Movement; Cell Transformation, Neoplastic; Cells, Cultured; Chromosome Aberrations; Colonic Neoplasms; Eye Neoplasms; Fibroblasts; Humans; Methylnitronitrosoguanidine; Mutation; Retinoblastoma; Skin; Tetradecanoylphorbol Acetate

1983
[Mechanisms of the tumor promoting effect of 12-0-tetradecanoyl phorbol 13-acetate on the ethylnitrosourea induced transplacental neurogenic carcinogenesis].
    No to shinkei = Brain and nerve, 1984, Volume: 36, Issue:4

    Topics: Animals; Brain Neoplasms; Carcinogens; Chromosome Aberrations; DNA, Neoplasm; Ethylnitrosourea; Female; Gene Expression Regulation; In Vitro Techniques; Maternal-Fetal Exchange; Neoplasm Proteins; Phorbols; Pregnancy; Rats; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Thymidine

1984
Tumor promoter phorbol 12-myristate 13-acetate induces a clastogenic factor in human lymphocytes.
    Proceedings of the National Academy of Sciences of the United States of America, 1982, Volume: 79, Issue:23

    Topics: Arachidonic Acids; Cells, Cultured; Chromosome Aberrations; Cyclooxygenase Inhibitors; Humans; Lymphocytes; Molecular Weight; Mutagens; Phorbols; Superoxide Dismutase; Tetradecanoylphorbol Acetate

1982
Chromosome abnormalities in chronic lymphocytic leukemia revealed by TPA as a mitogen.
    Cancer genetics and cytogenetics, 1983, Volume: 10, Issue:1

    Topics: Adult; Aged; Chromosome Aberrations; Chromosome Disorders; Clone Cells; Female; Humans; Karyotyping; Leukemia, Lymphoid; Lymphocyte Activation; Lymphocytes; Male; Middle Aged; Mitogens; Phorbols; Pokeweed Mitogens; Tetradecanoylphorbol Acetate

1983
Are there two different forms of neuroblastoma?
    Zeitschrift fur Kinderchirurgie : organ der Deutschen, der Schweizerischen und der Osterreichischen Gesellschaft fur Kinderchirurgie = Surgery in infancy and childhood, 1982, Volume: 35, Issue:2

    Topics: Cell Differentiation; Chromosome Aberrations; Humans; Neoplasm Regression, Spontaneous; Neuroblastoma; Tetradecanoylphorbol Acetate

1982
Induction of megakaryocytic differentiation in a newly established human leukemic cell line by 12-o-tetradecanoylphorbol-13-acetate.
    Zhonghua yi xue za zhi = Chinese medical journal; Free China ed, 1995, Volume: 56, Issue:1

    Topics: Adult; Antigens, CD; Cell Differentiation; Chromosome Aberrations; Humans; Leukemia, Megakaryoblastic, Acute; Male; Megakaryocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1995
Acute agranular CD4-positive natural killer cell leukemia. Comprehensive clinicopathologic studies including virologic and in vitro culture with inducing agents.
    Cancer, 1995, May-15, Volume: 75, Issue:10

    Topics: Acetamides; Butyrates; Butyric Acid; Chromosome Aberrations; Chromosome Disorders; DNA, Neoplasm; DNA, Viral; Fatal Outcome; Follow-Up Studies; Gene Rearrangement, T-Lymphocyte; Herpesvirus 4, Human; Herpesvirus 6, Human; Humans; Immunophenotyping; Killer Cells, Natural; Leukemia-Lymphoma, Adult T-Cell; Male; Microscopy, Electron; Middle Aged; Receptors, Antigen, T-Cell; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1995
Induction of different genetic changes by different classes of chemical carcinogens during progression of mouse skin tumors.
    Molecular carcinogenesis, 1994, Volume: 11, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Chromosome Aberrations; Chromosome Deletion; Genes, ras; Methylnitronitrosoguanidine; Mice; Mutation; Polymorphism, Restriction Fragment Length; Skin Neoplasms; Tetradecanoylphorbol Acetate; Trisomy

1994
A protective effect of chromosome 11 against DNA damage by TPA-activated neutrophils but not TPA acting alone.
    Carcinogenesis, 1994, Volume: 15, Issue:12

    Topics: Ataxia Telangiectasia; Carcinoma; Cell Line; Chromosome Aberrations; Chromosomes, Human, Pair 11; Cytotoxicity, Immunologic; DNA Damage; DNA, Neoplasm; Drug Resistance; Fibroblasts; Humans; Hybrid Cells; Keratinocytes; Micronucleus Tests; Neutrophils; Respiratory Burst; Tetradecanoylphorbol Acetate; Translocation, Genetic; Tumor Cells, Cultured; Urinary Bladder Neoplasms; X Chromosome

1994
Establishment and characterization of the T-cell line, EBT-8 latently infected with Epstein-Barr virus from large granular lymphocyte leukemia.
    Leukemia, 1994, Volume: 8, Issue:8

    Topics: Adult; Antigens, CD; Cell Line, Transformed; Chromosome Aberrations; Chromosome Disorders; Culture Techniques; DNA, Viral; Gene Rearrangement, T-Lymphocyte; Herpesvirus 4, Human; Humans; Immunophenotyping; In Situ Hybridization; Karyotyping; Leukemia, Lymphoid; Male; Restriction Mapping; T-Lymphocytes; Tetradecanoylphorbol Acetate

1994
Establishment and characterization of a novel human monocytic leukemia cell line (KP-1) expressing scavenger receptor.
    Pediatric research, 1993, Volume: 34, Issue:3

    Topics: Antigens, Neoplasm; Biomarkers, Tumor; Cell Differentiation; Child, Preschool; Cholesterol Esters; Chromosome Aberrations; Female; Gene Expression Regulation, Leukemic; Humans; Karyotyping; Leukemia, Monocytic, Acute; Lipoproteins, LDL; Macrophages; Membrane Proteins; Microscopy, Immunoelectron; Monokines; Neoplasm Proteins; Neoplastic Stem Cells; Phagocytosis; Receptors, Immunologic; Receptors, Lipoprotein; Receptors, Scavenger; Scavenger Receptors, Class B; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1993
Modification of genetic damage by dihomo-gamma-linolenic acid.
    Bulletin of environmental contamination and toxicology, 1994, Volume: 52, Issue:3

    Topics: 8,11,14-Eicosatrienoic Acid; Animals; Antimutagenic Agents; Benzo(a)pyrene; Chromosome Aberrations; Erythrocytes, Abnormal; Lymphocytes; Mice; Micronucleus Tests; Mutagens; Tetradecanoylphorbol Acetate; Thymidine; Time Factors

1994
Induction of micronuclei and karyotype aberrations during in vivo mouse skin carcinogenesis.
    Carcinogenesis, 1993, Volume: 14, Issue:11

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Chromosome Aberrations; Drug Administration Schedule; Drug Interactions; Karyotyping; Male; Methyl Methanesulfonate; Mice; Mice, Inbred Strains; Micronuclei, Chromosome-Defective; Micronucleus Tests; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate

1993
Isolation and characterization of an early T-helper/inducer cell line with a unique pattern of surface phenotype, constitutive cytokine secretion and myc oncogene expression.
    Leukemia, 1993, Volume: 7, Issue:12

    Topics: Antigens, CD; Antigens, Surface; Bone Marrow; Cell Adhesion; Cell Differentiation; Cell Line; Chromosome Aberrations; Cytokines; Fibronectins; Gene Expression; Gene Rearrangement, beta-Chain T-Cell Antigen Receptor; Genes, myc; Humans; Immunophenotyping; Polyploidy; Proto-Oncogene Proteins c-myc; RNA, Messenger; T-Lymphocytes, Helper-Inducer; Tetradecanoylphorbol Acetate

1993
Elevation of cell cycle control proteins during spontaneous immortalization of human keratinocytes.
    Molecular biology of the cell, 1993, Volume: 4, Issue:2

    Topics: CDC2 Protein Kinase; Cell Cycle; Chromosome Aberrations; Cyclins; Epidermal Growth Factor; Humans; In Vitro Techniques; Karyotyping; Keratinocytes; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta

1993
Establishment and characterization of two novel cytokine-responsive acute myeloid and monocytic leukemia cell lines, MUTZ-2 and MUTZ-3.
    Leukemia, 1996, Volume: 10, Issue:6

    Topics: Acid Phosphatase; Adult; Antineoplastic Agents; Base Sequence; Cell Differentiation; Cell Division; Chromosome Aberrations; Cytokines; Esterases; Hematopoietic Cell Growth Factors; Humans; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Middle Aged; Molecular Sequence Data; Peroxidase; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured

1996
Selective elimination of human lymphoid cells with unstable chromosome aberrations by p53-dependent apoptosis.
    Carcinogenesis, 1997, Volume: 18, Issue:1

    Topics: Apoptosis; Cell Line; Chromosome Aberrations; DNA Fragmentation; Dose-Response Relationship, Radiation; Humans; In Situ Hybridization, Fluorescence; Lymphocytes; Tetradecanoylphorbol Acetate

1997
[Generation of oxygen free radicals and clastogenesis in bone marrow cells of MRL/1 mice].
    Biulleten' eksperimental'noi biologii i meditsiny, 1997, Volume: 123, Issue:1

    Topics: Animals; Bone Marrow; Cells, Cultured; Chromosome Aberrations; Free Radicals; Luminescent Measurements; Male; Mice; Mice, Inbred MRL lpr; Mutagens; Quinoxalines; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Zymosan

1997
Optimized mitogen stimulation induces proliferation of neoplastic B cells in chronic lymphocytic leukemia: significance for cytogenetic analysis.The Tampere Chronic Lympocytic Leukemia group.
    Cytogenetics and cell genetics, 1998, Volume: 82, Issue:3-4

    Topics: Aged; B-Lymphocytes; Carcinogens; Cell Lineage; Chromosome Aberrations; Chromosomes, Human, Pair 11; DNA, Neoplasm; Female; Gene Deletion; Gene Expression Regulation, Neoplastic; Humans; Interleukin-2; Interphase; Leukemia, B-Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Mitogens; Mitosis; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

1998
Establishment and characterization of a steroidogenic human granulosa-like tumor cell line, KGN, that expresses functional follicle-stimulating hormone receptor.
    Endocrinology, 2001, Volume: 142, Issue:1

    Topics: Apoptosis; Aromatase; Bucladesine; Cell Culture Techniques; Cell Division; Chromosome Aberrations; Cyclic AMP; Female; Follicle Stimulating Hormone; Granulosa Cell Tumor; Humans; Interferon-gamma; Karyotyping; Middle Aged; Ovarian Neoplasms; Pregnenolone; Progesterone; Receptors, FSH; Recombinant Proteins; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

2001
Tumor promoter induces sister chromatid exchanges: relevance to mechanisms of carcinogenesis.
    Proceedings of the National Academy of Sciences of the United States of America, 1978, Volume: 75, Issue:12

    Topics: Cell Line; Cell Transformation, Neoplastic; Chromatids; Chromosome Aberrations; Chromosomes; Crossing Over, Genetic; Fluocinolone Acetonide; Leupeptins; Phorbols; Recombination, Genetic; Structure-Activity Relationship; Tetradecanoylphorbol Acetate

1978
Effect of tumor promoters, protease inhibitors, and repair processes on x-ray-induced sister chromatid exchanges in mouse cells.
    Proceedings of the National Academy of Sciences of the United States of America, 1979, Volume: 76, Issue:4

    Topics: Animals; Cell Line; Chromosome Aberrations; Chromosomes; DNA Repair; Mice; Phorbols; Protease Inhibitors; Tetradecanoylphorbol Acetate

1979
The effect of a tumor promotor, 12-O-tetradecanoyl-phorbol-13-acetate (TPA), on sister-chromatid exchange formation in cultured Chinese hamster cells.
    Mutation research, 1979, Volume: 67, Issue:4

    Topics: Animals; Cell Line; Chromatids; Chromosome Aberrations; Chromosomes; Cricetinae; Crossing Over, Genetic; Drug Evaluation, Preclinical; Female; Lung; Mutagens; Ovary; Phorbols; Tetradecanoylphorbol Acetate

1979
DNA repair and malignant transformation: effect of X irradiation, 12-O-tetradecanoyl-phorbol-13-acetate, and protease inhibitors on transformation and sister-chromatid exchanges in mouse 10T 1/2 cells.
    Radiation research, 1979, Volume: 79, Issue:2

    Topics: Animals; Antipain; Cell Survival; Cell Transformation, Neoplastic; Chromosome Aberrations; DNA Repair; Dose-Response Relationship, Radiation; In Vitro Techniques; Leupeptins; Mice; Phorbols; Protease Inhibitors; Sister Chromatid Exchange; Tetradecanoylphorbol Acetate; X-Rays

1979
Malignant transformation of human melanocytes: induction of a complete melanoma phenotype and genotype.
    Oncogene, 1992, Volume: 7, Issue:11

    Topics: 3T3 Cells; Animals; Antigens, Surface; Cell Transformation, Neoplastic; Chromosome Aberrations; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 6; Genes, ras; Genotype; HLA-DR Antigens; Humans; Melanocytes; Melanoma; Mice; Phenotype; Tetradecanoylphorbol Acetate

1992
Chromosomal abnormality limited to T4 lymphocytes in a patient with T-cell chronic lymphocytic leukaemia.
    European journal of haematology, 1990, Volume: 45, Issue:1

    Topics: Aged; B-Lymphocytes; CD4-Positive T-Lymphocytes; Cells, Cultured; Chromosome Aberrations; Chromosome Inversion; Chromosomes, Human, Pair 14; Gene Rearrangement; Gene Rearrangement, T-Lymphocyte; Genes, Immunoglobulin; Humans; Immunoenzyme Techniques; Karyotyping; Leukemia, Prolymphocytic, T-Cell; Male; Mitosis; Phenotype; Phytohemagglutinins; T-Lymphocytes; Tetradecanoylphorbol Acetate; Translocation, Genetic; Y Chromosome

1990
Chromosome and gene rearrangements in immortalized human lymphocytes infected with human T-lymphotropic virus type I.
    Cancer research, 1990, Sep-01, Volume: 50, Issue:17 Suppl

    Topics: Cells, Cultured; Chromosome Aberrations; Gene Rearrangement, beta-Chain T-Cell Antigen Receptor; HTLV-I Infections; Humans; Lymphocytes; Tetradecanoylphorbol Acetate

1990
Distribution of phorbol ester TPA-induced structural chromosomal aberrations in HeLa cells.
    Carcinogenesis, 1990, Volume: 11, Issue:11

    Topics: Chromosome Aberrations; Chromosome Fragile Sites; Chromosome Fragility; Chromosome Mapping; HeLa Cells; Humans; Tetradecanoylphorbol Acetate

1990
Ca antagonist verapamil and tumor promoter 12-O-tetradecanoylphorbol-13- acetate (TPA) induce chromosomal aberrations in human lymphocytes.
    Mutation research, 1990, Volume: 244, Issue:2

    Topics: Chromosome Aberrations; Humans; Lymphocytes; Tetradecanoylphorbol Acetate; Verapamil

1990
Cytogenetic effects of phorbol ester tumor promoters: possible role in multistep tumorigenesis.
    Progress in clinical and biological research, 1990, Volume: 340D

    Topics: Chromosome Aberrations; Chromosomes; Chromosomes, Human; HeLa Cells; Humans; Neoplasms; Phorbol Esters; Tetradecanoylphorbol Acetate

1990
Tumor induction in initiated mouse skin by phorbol esters and methyl methanesulfonate: correlation between chromosomal damage and conversion ('stage I of tumor promotion') in vivo.
    Carcinogenesis, 1989, Volume: 10, Issue:4

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Chromosome Aberrations; Female; Methyl Methanesulfonate; Mice; Phorbol Esters; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate

1989
2-(2-hydroxy-4-methylphenyl)aminothiazole hydrochloride as a dual inhibitor of cyclooxygenase/lipoxygenase and a free radical scavenger. 1st communication: in vitro studies.
    Arzneimittel-Forschung, 1989, Volume: 39, Issue:10

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Cells, Cultured; Chromosome Aberrations; Cyclooxygenase Inhibitors; Free Radicals; Humans; In Vitro Techniques; Leukotrienes; Lipid Peroxidation; Lipoxygenase Inhibitors; Oxygen Consumption; Rabbits; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Thiazoles

1989
Cytogenetic effects caused by phorbol ester tumor promoters in HeLa cells: mechanistic aspects.
    Carcinogenesis, 1989, Volume: 10, Issue:12

    Topics: Carcinogens; Chromatids; Chromosome Aberrations; HeLa Cells; Humans; Kinetics; Metaphase; Phorbol Esters; Tetradecanoylphorbol Acetate; Time Factors

1989
Chromosomal and c-K-ras oncogene alterations induced by a chemical carcinogen and phorbol ester in skin fibroblasts of individuals with familial polyposis coli.
    Carcinogenesis, 1988, Volume: 9, Issue:10

    Topics: Adenomatous Polyposis Coli; Adolescent; Adult; Cell Division; Cells, Cultured; Child; Chromosome Aberrations; Deoxyribonuclease EcoRI; Fibroblasts; Genes, ras; Humans; Methylnitronitrosoguanidine; Ploidies; Skin; Tetradecanoylphorbol Acetate

1988
Enhancement of bovine papillomavirus-induced cell transformation by tumour promoters.
    Cancer letters, 1988, Dec-01, Volume: 43, Issue:1-2

    Topics: Animals; Bovine papillomavirus 1; Carcinogens; Cell Transformation, Viral; Chromosome Aberrations; Diterpenes; Mice; Mice, Inbred C3H; Micronucleus Tests; Papillomaviridae; Phorbol Esters; Sister Chromatid Exchange; Terpenes; Tetradecanoylphorbol Acetate

1988
Treatment of lymphocyte cultures with a hypoxanthine-xanthine oxidase system induces the formation of transferable clastogenic material.
    Journal of free radicals in biology & medicine, 1985, Volume: 1, Issue:1

    Topics: Arachidonic Acid; Arachidonic Acids; Catalase; Cells, Cultured; Chromosome Aberrations; DNA; Free Radicals; Glutathione Peroxidase; Humans; Hypoxanthine; Hypoxanthines; Lymphocytes; Mutagens; Superoxide Dismutase; Superoxides; Tetradecanoylphorbol Acetate; Thiobarbiturates; Xanthine Oxidase

1985
Phorbol ester-induced formation of clastogenic factor from human monocytes.
    Carcinogenesis, 1987, Volume: 8, Issue:4

    Topics: Arachidonic Acid; Arachidonic Acids; Chromosome Aberrations; Humans; Leukotrienes; Lipid Metabolism; Lipid Peroxides; Monocytes; Mutagens; Platelet Activating Factor; Tetradecanoylphorbol Acetate

1987
Purified protein kinase C phosphorylates a 47-kDa protein in control neutrophil cytoplasts but not in neutrophil cytoplasts from patients with the autosomal form of chronic granulomatous disease.
    The Journal of biological chemistry, 1988, Feb-15, Volume: 263, Issue:5

    Topics: Chromosome Aberrations; Chromosome Disorders; Electrophoresis, Polyacrylamide Gel; Granulomatous Disease, Chronic; Humans; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Oxygen Consumption; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate; Zymosan

1988
New cell line from hairy-cell leukemia: confirmation of leukemic cell origin by karyotype and Ig gene analysis.
    International journal of cancer, 1988, Jul-15, Volume: 42, Issue:1

    Topics: Adult; Antibodies, Monoclonal; Cell Line; Cell Membrane; Chromosome Aberrations; Humans; Immunoglobulins; Karyotyping; Leukemia, Hairy Cell; Male; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1988
Retinoic acid-induced monocytic differentiation of HL60/MRI, a cell line derived from a transplantable HL60 tumor.
    Cancer research, 1987, Mar-01, Volume: 47, Issue:5

    Topics: Acetamides; Animals; Antigens, Surface; Cell Differentiation; Cell Line; Chromosome Aberrations; Dimethyl Sulfoxide; Humans; Isoenzymes; Leukemia, Myeloid, Acute; Mice; Mice, Inbred BALB C; Monocytes; Neoplasm Transplantation; Tetradecanoylphorbol Acetate; Tretinoin

1987
Familial polyposis coli: growth characteristics of karyotypically variable cultured fibroblasts, response to epidermal growth factor and the tumour promoter 12-0-tetradecanoyl phorbol-13-acetate.
    Journal of medical genetics, 1986, Volume: 23, Issue:2

    Topics: Cell Adhesion; Cell Count; Cell Division; Cells, Cultured; Chromosome Aberrations; Colonic Polyps; Culture Media; Epidermal Growth Factor; Fibroblasts; Humans; Karyotyping; Skin; Tetradecanoylphorbol Acetate

1986
Clonal chromosome abnormalities in chronic lymphocytic leukemia patients revealed by TPA stimulation of whole blood cultures.
    Cancer genetics and cytogenetics, 1987, Volume: 25, Issue:1

    Topics: Aged; Bone Marrow; Cells, Cultured; Chromosome Aberrations; Chromosome Banding; Female; Humans; Karyotyping; Leukemia, Lymphoid; Lymphocytes; Male; Middle Aged; Mitogens; Oncogenes; Prognosis; Tetradecanoylphorbol Acetate

1987
Establishment and characterization of a B-cell line from a patient with acute lymphoblastic leukemia.
    Leukemia research, 1985, Volume: 9, Issue:1

    Topics: Acid Phosphatase; B-Lymphocytes; Cell Line; Child; Chromosome Aberrations; Histocytochemistry; Humans; Leukemia, Lymphoid; Male; Naphthol AS D Esterase; Tetradecanoylphorbol Acetate

1985
Human acute leukemia cell line with the t(4;11) chromosomal rearrangement exhibits B lineage and monocytic characteristics.
    Blood, 1985, Volume: 65, Issue:1

    Topics: Adult; Antigens, Differentiation, B-Lymphocyte; Antigens, Neoplasm; Antigens, Surface; B-Lymphocytes; Cell Line; Cell Transformation, Neoplastic; Chromosome Aberrations; Chromosome Disorders; Clone Cells; Female; Histocytochemistry; Humans; Immunoglobulins; Karyotyping; Leukemia; Monocytes; Tetradecanoylphorbol Acetate

1985
Lipid peroxidation products and clastogenic material in culture media of human leukocytes exposed to the tumor promoter phorbol-myristate-acetate.
    Journal of free radicals in biology & medicine, 1985, Volume: 1, Issue:5-6

    Topics: Arachidonic Acid; Arachidonic Acids; Cells, Cultured; Chromosome Aberrations; Culture Media; Dose-Response Relationship, Drug; Free Radicals; Humans; Leukocytes; Lipid Peroxides; Malondialdehyde; Oxygen; Phorbols; Tetradecanoylphorbol Acetate; Thiobarbiturates

1985
Tumor promoter 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced chromosome aberrations in mouse keratinocyte cell lines: a possible genetic mechanism of tumor promotion.
    Carcinogenesis, 1985, Volume: 6, Issue:10

    Topics: Animals; Cell Line; Chromosome Aberrations; Cocarcinogenesis; Dose-Response Relationship, Drug; Epidermal Cells; Epidermis; Gene Amplification; Karyotyping; Mice; Phorbol Esters; Phorbols; Structure-Activity Relationship; Tetradecanoylphorbol Acetate

1985
Relationship of animal cell transformation models to the study of human neoplastic cell transformation.
    Carcinogenesis; a comprehensive survey, 1985, Volume: 9

    Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Chromosome Aberrations; Cricetinae; DNA; Humans; Mesocricetus; Models, Biological; Oncogenes; Tetradecanoylphorbol Acetate

1985