tetracaine has been researched along with Melanoma in 3 studies
Tetracaine: A potent local anesthetic of the ester type used for surface and spinal anesthesia.
tetracaine : A benzoate ester in which 4-N-butylbenzoic acid and 2-(dimethylamino)ethanol have combined to form the ester bond; a local ester anaesthetic (ester caine) used for surface and spinal anaesthesia.
Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Specifically, tetracaine has a potent antitumor effect in diverse cancers, including neuroblastoma, breast cancer, and melanoma; however, the underlying molecular mechanisms remain unclear." | 8.12 | Tetracaine hydrochloride induces cell cycle arrest in melanoma by downregulating hnRNPA1. ( Chen, Y; Feng, J; Huang, X; Jia, J; Jiang, X; Liao, Y; Yi, J; Yi, P, 2022) |
| " Specifically, tetracaine has a potent antitumor effect in diverse cancers, including neuroblastoma, breast cancer, and melanoma; however, the underlying molecular mechanisms remain unclear." | 4.12 | Tetracaine hydrochloride induces cell cycle arrest in melanoma by downregulating hnRNPA1. ( Chen, Y; Feng, J; Huang, X; Jia, J; Jiang, X; Liao, Y; Yi, J; Yi, P, 2022) |
| "Tertiary amine local anesthetics, such as dibucaine and tetracaine, have been found to reversibly modify the blood-borne implantation and experimental metastatic properties of B16 melanoma cells in syngeneic C57BL/6 mice." | 3.67 | Effects of tertiary amine local anesthetics on the blood-borne implantation and cell surface properties of metastatic mouse melanoma cells. ( Fidler, IJ; Nicolson, GL; Poste, G, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (66.67) | 2.80 |
| Authors | Studies |
|---|---|
| Huang, X | 1 |
| Chen, Y | 1 |
| Yi, J | 1 |
| Yi, P | 1 |
| Jia, J | 1 |
| Liao, Y | 1 |
| Feng, J | 1 |
| Jiang, X | 1 |
| Tibensky, M | 1 |
| Blasko, F | 1 |
| Vargovic, P | 1 |
| Jakubikova, J | 1 |
| Cholujova, D | 1 |
| Jakubechova, J | 1 |
| Mravec, B | 1 |
| Nicolson, GL | 1 |
| Fidler, IJ | 1 |
| Poste, G | 1 |
3 other studies available for tetracaine and Melanoma
| Article | Year |
|---|---|
Tetracaine hydrochloride induces cell cycle arrest in melanoma by downregulating hnRNPA1.
Topics: Animals; Cell Cycle Checkpoints; Cell Proliferation; Dose-Response Relationship, Drug; Down-Regulati | 2022 |
Topical application of local anesthetics to melanoma increases the efficacy of anti-PD-1 therapy.
Topics: Anesthetics, Local; Animals; Lidocaine; Melanoma; Mice; Tetracaine | 2023 |
Effects of tertiary amine local anesthetics on the blood-borne implantation and cell surface properties of metastatic mouse melanoma cells.
Topics: Anesthetics, Local; Animals; Calcium; Cell Adhesion; Cell Membrane; Cytoskeleton; Female; Glycoprote | 1986 |