tetracaine has been researched along with Lacerations in 19 studies
Tetracaine: A potent local anesthetic of the ester type used for surface and spinal anesthesia.
tetracaine : A benzoate ester in which 4-N-butylbenzoic acid and 2-(dimethylamino)ethanol have combined to form the ester bond; a local ester anaesthetic (ester caine) used for surface and spinal anaesthesia.
Lacerations: Torn, ragged, mangled wounds.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treating minor lacerations with lidocaine-epinephrine-tetracaine before wound closure with tissue adhesive reduced ratings of pain and increased the proportion of pain-free repairs among children aged 3 months to 17 years." | 9.17 | Efficacy of pain control with topical lidocaine-epinephrine-tetracaine during laceration repair with tissue adhesive in children: a randomized controlled trial. ( Duncan, MJ; Harman, S; Petrcich, W; Ying, Y; Zemek, R, 2013) |
| "To determine the effectiveness of lidocaine-adrenaline-tetracaine (LAT) in providing adequate anesthesia for the repair of finger lacerations and to monitor the risk of digital ischemia following application of LAT gel to finger lacerations." | 9.11 | The anesthetic effectiveness of lidocaine-adrenaline-tetracaine gel on finger lacerations. ( Bergholte, J; Brousseau, DC; Hennes, H; Kim, MK; White, NJ, 2004) |
| "Lidocaine infiltration was performed if any sign of pain was observed." | 7.71 | [Suture of skin lacerations using LAT gel (lidocaine, adrenaline, tetracaine)]. ( Alió Y Sanz, JL; Chipont Benabent, E; García-Hermosa, P, 2001) |
| "Treating minor lacerations with lidocaine-epinephrine-tetracaine before wound closure with tissue adhesive reduced ratings of pain and increased the proportion of pain-free repairs among children aged 3 months to 17 years." | 5.17 | Efficacy of pain control with topical lidocaine-epinephrine-tetracaine during laceration repair with tissue adhesive in children: a randomized controlled trial. ( Duncan, MJ; Harman, S; Petrcich, W; Ying, Y; Zemek, R, 2013) |
| "To determine the effectiveness of lidocaine-adrenaline-tetracaine (LAT) in providing adequate anesthesia for the repair of finger lacerations and to monitor the risk of digital ischemia following application of LAT gel to finger lacerations." | 5.11 | The anesthetic effectiveness of lidocaine-adrenaline-tetracaine gel on finger lacerations. ( Bergholte, J; Brousseau, DC; Hennes, H; Kim, MK; White, NJ, 2004) |
| "The literature has shown that the induction of anaesthesia in lacerations has remained largely unchanged over the past few years, with lidocaine infiltration still the preferred method." | 4.85 | The use of topical anaesthesia during repair of minor lacerations in Departments of Emergency Medicine: a literature review. ( Jenkins, MG; Kelly, OJ; Little, C; McCarron, P; Murphy, D, 2009) |
| "Lidocaine infiltration was performed if any sign of pain was observed." | 3.71 | [Suture of skin lacerations using LAT gel (lidocaine, adrenaline, tetracaine)]. ( Alió Y Sanz, JL; Chipont Benabent, E; García-Hermosa, P, 2001) |
| " Skin lacerations are common in children and their repair is a very unpleasant experience for a child." | 1.56 | Lidocaine-Epinephrine-Tetracaine Gel Is More Efficient than Eutectic Mixture of Local Anesthetics and Mepivacaine Injection for Pain Control during Skin Repair in Children: A Prospective, Propensity Score Matched Two-Center Study. ( Boettcher, J; Boettcher, M; Königs, I; Reinshagen, K; Wenskus, J, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (42.11) | 29.6817 |
| 2010's | 7 (36.84) | 24.3611 |
| 2020's | 4 (21.05) | 2.80 |
| Authors | Studies |
|---|---|
| Siembieda, J | 1 |
| Heyming, T | 1 |
| Padlipsky, P | 1 |
| Young, KD | 1 |
| Scribner-O'Pray, M | 1 |
| Taylor, ED | 1 |
| Krause, E | 1 |
| Nickel, A | 1 |
| Bergmann, KR | 1 |
| Königs, I | 1 |
| Wenskus, J | 1 |
| Boettcher, J | 1 |
| Reinshagen, K | 1 |
| Boettcher, M | 1 |
| Jones, A | 1 |
| Kelly, E | 1 |
| Borumandi, F | 1 |
| Martin, HA | 1 |
| Lambert, C | 1 |
| Goldman, RD | 1 |
| Harman, S | 1 |
| Zemek, R | 1 |
| Duncan, MJ | 1 |
| Ying, Y | 1 |
| Petrcich, W | 1 |
| Wang, B | 1 |
| Hill, VK | 1 |
| Wilson, MH | 1 |
| Felstead, AM | 1 |
| Sherman, JM | 1 |
| Sheppard, P | 1 |
| Hoppa, E | 1 |
| Krief, W | 1 |
| Avarello, J | 1 |
| Tayeb, BO | 1 |
| Eidelman, A | 1 |
| Eidelman, CL | 1 |
| McNicol, ED | 1 |
| Carr, DB | 1 |
| Little, C | 1 |
| Kelly, OJ | 1 |
| Jenkins, MG | 1 |
| Murphy, D | 1 |
| McCarron, P | 1 |
| McNulty, RJ | 1 |
| Handley, TP | 1 |
| Devlin, MF | 1 |
| Bush, S | 1 |
| Priestley, S | 1 |
| Kelly, AM | 1 |
| Chow, L | 1 |
| Powell, C | 1 |
| Williams, A | 1 |
| Bank, DE | 1 |
| Diaz, L | 1 |
| Behrman, DA | 1 |
| Delaney, J | 1 |
| Bizzocco, S | 1 |
| White, NJ | 1 |
| Kim, MK | 1 |
| Brousseau, DC | 1 |
| Bergholte, J | 1 |
| Hennes, H | 1 |
| Singer, AJ | 1 |
| Stark, MJ | 1 |
| Van-Liaw, P | 1 |
| Chipont Benabent, E | 1 |
| García-Hermosa, P | 1 |
| Alió Y Sanz, JL | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparison of 2 Application Techniques for LET (Lidocaine 4%; Epinephrine 0.1%; Tetracaine 0.5%) Gel Used Prior to Simple Laceration Repair in Children[NCT04203225] | Phase 4 | 48 participants (Actual) | Interventional | 2017-05-22 | Completed | ||
| Comparison of 2 Application Techniques for LET (Lidocaine 4%; Epinephrine 0.1%; Tetracaine 0.5%) Gel Used Prior to Simple Laceration Repair[NCT04536493] | Phase 4 | 48 participants (Actual) | Interventional | 2019-06-19 | Completed | ||
| Prospective Evaluation of Topical Analgesia Using a Lidocaine/Prilocaine Cream for Laceration Repair in the Emergency Department[NCT03071601] | Phase 4 | 132 participants (Actual) | Interventional | 2017-12-01 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Need for additional infiltrated local anesthetic (lidocaine) (NCT04203225)
Timeframe: At any time during suturing procedure, time frame is duration of procedure, generally 10-20 minutes, less than one hour. Determined by chart review immediately after procedure completion.
| Intervention | Participants (Count of Participants) |
|---|---|
| Single LET | 4 |
| Triple LET | 5 |
Pain score self-rated by patient on 100m Visual Analog Pain scale, minimum value 0, maximum value 100, higher scores equal more pain (worse outcome) (NCT04203225)
Timeframe: Immediately on placement or attempt at placement of first suture
| Intervention | mm (Mean) |
|---|---|
| Single LET | 16 |
| Triple LET | 16 |
4 reviews available for tetracaine and Lacerations
| Article | Year |
|---|---|
Factors Associated With Low Procedural Pain Scores Among 1- to 5-Year-Old Patients Undergoing Facial Laceration Repair.
Topics: Anti-Anxiety Agents; Child, Preschool; Epinephrine; Humans; Infant; Lacerations; Lidocaine; Pain; Pa | 2023 |
Topical anaesthetics for pain control during repair of dermal laceration.
Topics: Adult; Anesthetics, Local; Child; Cocaine; Drug Combinations; Epinephrine; Humans; Lacerations; Pain | 2017 |
The use of topical anaesthesia during repair of minor lacerations in Departments of Emergency Medicine: a literature review.
Topics: Administration, Topical; Anesthetics, Local; Cocaine; Drug Combinations; Epinephrine; Humans; Lacera | 2009 |
Is cocaine needed in topical anaesthesia?
Topics: Anesthetics, Local; Cocaine; Epinephrine; Humans; Lacerations; Tetracaine | 2002 |
5 trials available for tetracaine and Lacerations
| Article | Year |
|---|---|
Triple Versus Single Application of Lidocaine, Epinephrine, and Tetracaine for Laceration Repair in Children.
Topics: Adolescent; Child; Epinephrine; Humans; Lacerations; Lidocaine; Single-Blind Method; Tetracaine | 2022 |
Efficacy of pain control with topical lidocaine-epinephrine-tetracaine during laceration repair with tissue adhesive in children: a randomized controlled trial.
Topics: Administration, Cutaneous; Adolescent; Anesthetics, Local; Child; Child, Preschool; Drug Combination | 2013 |
Application of topical local anesthetic at triage reduces treatment time for children with lacerations: a randomized controlled trial.
Topics: Anesthesia, Local; Child; Child, Preschool; Double-Blind Method; Emergency Service, Hospital; Epinep | 2003 |
The anesthetic effectiveness of lidocaine-adrenaline-tetracaine gel on finger lacerations.
Topics: Anesthesia, Local; Anesthetics, Local; Child; Drug Therapy, Combination; Epinephrine; Female; Finger | 2004 |
Pretreatment of lacerations with lidocaine, epinephrine, and tetracaine at triage: a randomized double-blind trial.
Topics: Administration, Topical; Adolescent; Adult; Aged; Anesthesia, Local; Anesthetics, Local; Child; Chil | 2000 |
10 other studies available for tetracaine and Lacerations
| Article | Year |
|---|---|
Lidocaine-Epinephrine-Tetracaine Gel Is More Efficient than Eutectic Mixture of Local Anesthetics and Mepivacaine Injection for Pain Control during Skin Repair in Children: A Prospective, Propensity Score Matched Two-Center Study.
Topics: Administration, Topical; Anesthetics, Combined; Child; Epinephrine; Female; Gels; Humans; Laceration | 2020 |
The Role of Topical Anesthetics in the Treatment of Pediatric Facial Lacerations.
Topics: Anesthesia, Local; Anesthetics, Local; Child; Epinephrine; Humans; Lacerations; Lidocaine; Tetracain | 2021 |
The Power of Lidocaine, Epinephrine, and Tetracaine (LET) and a Child Life Specialist When Suturing Lacerations in Children.
Topics: Anesthetics, Local; Child; Drug Combinations; Epinephrine; Gels; Humans; Lacerations; Lidocaine; Ped | 2017 |
Pain management for children needing laceration repair.
Topics: Administration, Cutaneous; Anesthetics, Local; Child; Drug Combinations; Epinephrine; Humans; Lacera | 2018 |
LAT gel, a powerful tool underused in the repair of paediatric lacerations.
Topics: Anesthetics, Local; Child; Debridement; Drug Combinations; Emergency Service, Hospital; Epinephrine; | 2014 |
Let Us Use LET: A Quality Improvement Initiative.
Topics: Administration, Topical; Anesthetics, Combined; Anesthetics, Local; Child; Drug Combinations; Emerge | 2016 |
Reducing the need for general anaesthesia in children: use of LAT gel in treating facial lacerations.
Topics: Administration, Topical; Anesthesia, General; Anesthesia, Local; Anesthetics, Combined; Anesthetics, | 2013 |
Tongue entrapment in an aluminum juice can.
Topics: 4-Aminobenzoic Acid; Airway Obstruction; Anesthetics, Local; Benzalkonium Compounds; Benzocaine; Cet | 2004 |
Resident's column: Use of topical anesthetics in children.
Topics: Administration, Cutaneous; Anesthetics, Local; Chin; Female; Humans; Infant; Injections, Subcutaneou | 2001 |
[Suture of skin lacerations using LAT gel (lidocaine, adrenaline, tetracaine)].
Topics: Adolescent; Adult; Aged; Anesthetics, Local; Child; Child, Preschool; Dermatologic Surgical Procedur | 2001 |