tetracaine has been researched along with Eye Pain in 16 studies
Tetracaine: A potent local anesthetic of the ester type used for surface and spinal anesthesia.
tetracaine : A benzoate ester in which 4-N-butylbenzoic acid and 2-(dimethylamino)ethanol have combined to form the ester bond; a local ester anaesthetic (ester caine) used for surface and spinal anaesthesia.
Eye Pain: A dull or sharp painful sensation associated with the outer or inner structures of the eyeball, having different causes.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The objective of this study was to test the hypothesis that topical tetracaine would be safe to use for 24 hours and would not affect corneal healing, that patients would experience more pain relief, and that patients would perceive tetracaine to be more effective than saline eye drops for the treatment of pain caused by corneal abrasions." | 2.79 | Topical tetracaine used for 24 hours is safe and rated highly effective by patients for the treatment of pain caused by corneal abrasions: a double-blind, randomized clinical trial. ( Densie, IK; Herbison, P; Waldman, N, 2014) |
| " All six studies demonstrated that a short course of dilute topical anesthetic provided efficacious analgesia without adverse effects or delayed epithelial healing." | 2.52 | The Safety of Topical Anesthetics in the Treatment of Corneal Abrasions: A Review. ( Milne, K; Otterness, K; Rezaie, S; Swaminathan, A, 2015) |
| "Postoperative pain was significantly elevated in patients who used tetracaine on POD 1 and POD 7." | 1.56 | Assessment of Factors Associated With Postoperative Pain After Photorefractive Keratectomy. ( Apsey, DA; Caldwell, MC; Evangelista, C; Gillis, J; Justin, GA; Legault, GL; Palochak, CMA; Santamaria, J; Steigleman, WA, 2020) |
| "Tetracaine was dispensed at the initial visit for 303 SCA presentations (57%) and inappropriately for 141 NSCA presentations (14%)." | 1.48 | An Observational Study to Determine Whether Routinely Sending Patients Home With a 24-Hour Supply of Topical Tetracaine From the Emergency Department for Simple Corneal Abrasion Pain Is Potentially Safe. ( Densie, I; Giddings, G; Gray, A; McMaster, S; Meanley, J; Waldman, N; Winrow, B, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 13 (81.25) | 24.3611 |
| 2020's | 3 (18.75) | 2.80 |
| Authors | Studies |
|---|---|
| Palochak, CMA | 1 |
| Santamaria, J | 1 |
| Justin, GA | 1 |
| Apsey, DA | 1 |
| Caldwell, MC | 1 |
| Steigleman, WA | 1 |
| Evangelista, C | 1 |
| Legault, GL | 1 |
| Gillis, J | 1 |
| Jehle, D | 1 |
| Lark, MC | 1 |
| O'Brien, C | 1 |
| Shipman, S | 1 |
| Painter, K | 1 |
| Keuchel, M | 1 |
| Bogie, C | 1 |
| Waldman, N | 4 |
| Winrow, B | 1 |
| Densie, I | 1 |
| Gray, A | 1 |
| McMaster, S | 1 |
| Giddings, G | 1 |
| Meanley, J | 1 |
| Crabb, MG | 1 |
| Liu, E | 1 |
| Freeman, A | 1 |
| Hsu, T | 1 |
| Supramaniam, D | 1 |
| Kaidonis, G | 1 |
| Glading, J | 1 |
| Keane, MC | 1 |
| Cugati, S | 1 |
| Lake, SR | 1 |
| Saha, N | 1 |
| Landers, J | 1 |
| Craig, JE | 1 |
| Densie, IK | 3 |
| Herbison, P | 2 |
| Ufberg, JW | 1 |
| Karras, DJ | 1 |
| Pruet, CM | 1 |
| Feldman, RM | 1 |
| Kim, G | 1 |
| Tijunelis, M | 1 |
| Tozer, K | 1 |
| Swaminathan, A | 1 |
| Otterness, K | 1 |
| Milne, K | 1 |
| Rezaie, S | 1 |
| Blaha, GR | 1 |
| Tilton, EP | 1 |
| Barouch, FC | 1 |
| Marx, JL | 1 |
| Castellanos, MA | 1 |
| Schwartz, S | 1 |
| Leal, R | 1 |
| Chan, RV | 1 |
| Quiroz-Mercado, H | 1 |
| Shah, NV | 1 |
| Vaddavalli, PK | 1 |
| Chow, JH | 1 |
| Roman, JS | 1 |
| Shi, W | 1 |
| Yoo, SH | 1 |
| Sanabria, MR | 1 |
| Montero, JA | 1 |
| Losada, MV | 1 |
| Fernández-Muñoz, M | 1 |
| Galindo, A | 1 |
| Fernández, I | 1 |
| Coco, RM | 1 |
| Sampedro, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Short Term Topical Tetracaine is Safe and Highly Efficacious for the Treatment of Pain Caused by Corneal Abrasions: a Double-blind Randomized Clinical Trial[NCT04187417] | 118 participants (Actual) | Interventional | 2015-01-01 | Completed | |||
| Treatment of Corneal Abrasions With Topical Tetracaine: an Evaluation of Safety and Efficacy[NCT02771392] | Phase 2/Phase 3 | 120 participants (Anticipated) | Interventional | 2016-06-30 | Not yet recruiting | ||
| A Prospective, Randomised, Single-masked Comparison of Topical Anesthesia and Topical Combined Subconjunctival (Two-step) Anesthesia in Intravitreal Injection[NCT03871062] | 60 participants (Anticipated) | Interventional | 2019-03-08 | Recruiting | |||
| Comparison of Three Different Anesthetic Approaches for Intravitreal Injections: A Prospective Randomized Trial[NCT02263690] | Phase 4 | 92 participants (Actual) | Interventional | 2014-06-30 | Completed | ||
| Comparison of 0.5% Tetracaine Drops Versus 2% Lidocaine Gel for Anesthetic Efficacy and Comfort in Patients Undergoing LASIK[NCT01383200] | Phase 4 | 11 participants (Actual) | Interventional | 2011-06-30 | Terminated (stopped due to eyes that received gel had slightly thinner than intended flaps) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Do you have sharp pain in your eye? Pain will be assessed by units on a scale of 1-5: 1 means no symptoms, 2 means slight discomfort, 3 means mild discomfort, 4 means moderate discomfort, and 5 means severe discomfort (NCT01383200)
Timeframe: 1 hour (60minutes) post LASIK operation
| Intervention | Score on scale (Mean) |
|---|---|
| Tetracaine | 1.95 |
| Lidocaine | 2.01 |
1 review available for tetracaine and Eye Pain
| Article | Year |
|---|---|
The Safety of Topical Anesthetics in the Treatment of Corneal Abrasions: A Review.
Topics: Anesthetics, Local; Corneal Injuries; Eye Pain; Humans; Propoxycaine; Tetracaine; Wound Healing | 2015 |
6 trials available for tetracaine and Eye Pain
| Article | Year |
|---|---|
Short-Term Topical Tetracaine Is Highly Efficacious for the Treatment of Pain Caused by Corneal Abrasions: A Double-Blind, Randomized Clinical Trial.
Topics: Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics; Corneal Injuries; D | 2021 |
The intravitreal injection pain study: a randomized control study comparing subjective pain with injection technique.
Topics: Administration, Ophthalmic; Adult; Anesthetics, Local; Angiogenesis Inhibitors; Eye Pain; Humans; In | 2019 |
Topical tetracaine used for 24 hours is safe and rated highly effective by patients for the treatment of pain caused by corneal abrasions: a double-blind, randomized clinical trial.
Topics: Administration, Ophthalmic; Adolescent; Adult; Aged; Anesthetics, Local; Cornea; Corneal Injuries; D | 2014 |
Topical tetracaine used for 24 hours is safe and rated highly effective by patients for the treatment of pain caused by corneal abrasions: a double-blind, randomized clinical trial.
Topics: Administration, Ophthalmic; Adolescent; Adult; Aged; Anesthetics, Local; Cornea; Corneal Injuries; D | 2014 |
Topical tetracaine used for 24 hours is safe and rated highly effective by patients for the treatment of pain caused by corneal abrasions: a double-blind, randomized clinical trial.
Topics: Administration, Ophthalmic; Adolescent; Adult; Aged; Anesthetics, Local; Cornea; Corneal Injuries; D | 2014 |
Topical tetracaine used for 24 hours is safe and rated highly effective by patients for the treatment of pain caused by corneal abrasions: a double-blind, randomized clinical trial.
Topics: Administration, Ophthalmic; Adolescent; Adult; Aged; Anesthetics, Local; Cornea; Corneal Injuries; D | 2014 |
Randomized trial of anesthetic methods for intravitreal injections.
Topics: Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Angiogenesis Inhibitors; Antibodies, | 2011 |
Randomized trial of anesthetic methods for intravitreal injections.
Topics: Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Angiogenesis Inhibitors; Antibodies, | 2011 |
Randomized trial of anesthetic methods for intravitreal injections.
Topics: Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Angiogenesis Inhibitors; Antibodies, | 2011 |
Randomized trial of anesthetic methods for intravitreal injections.
Topics: Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Angiogenesis Inhibitors; Antibodies, | 2011 |
Prospective, double-masked, randomized trial comparing lidocaine gel to tetracaine drops in femtosecond laser-assisted LASIK.
Topics: Anesthetics, Local; Corneal Stroma; Double-Blind Method; Eye Pain; Gels; Humans; Intraoperative Comp | 2012 |
Ocular pain after intravitreal injection.
Topics: Aged; Aged, 80 and over; Anesthetics, Local; Angiogenesis Inhibitors; Anti-Bacterial Agents; Anti-In | 2013 |
9 other studies available for tetracaine and Eye Pain
| Article | Year |
|---|---|
Assessment of Factors Associated With Postoperative Pain After Photorefractive Keratectomy.
Topics: Administration, Ophthalmic; Adult; Anesthetics, Local; Eye Pain; Female; Humans; Lasers, Excimer; Ma | 2020 |
Failure of painful eye movements to respond to topical anesthetics supports the diagnosis of optic neuritis.
Topics: Adult; Anesthetics, Local; Eye Movements; Eye Pain; Female; Humans; Magnetic Resonance Imaging; Midd | 2021 |
An Observational Study to Determine Whether Routinely Sending Patients Home With a 24-Hour Supply of Topical Tetracaine From the Emergency Department for Simple Corneal Abrasion Pain Is Potentially Safe.
Topics: Adolescent; Adult; Anesthetics, Local; Corneal Injuries; Drug Administration Schedule; Emergency Ser | 2018 |
Dogma challenged: tetracaine for corneal abrasions?
Topics: Anesthetics, Local; Corneal Injuries; Eye Injuries; Eye Pain; Female; Humans; Male; Tetracaine | 2014 |
Re: "topical tetracaine used for 24 hours is safe and rated highly effective by patients for the treatment of pain caused by corneal abrasions: a double-blind, randomized clinical trial".
Topics: Anesthetics, Local; Corneal Injuries; Eye Injuries; Eye Pain; Female; Humans; Male; Tetracaine | 2014 |
In reply.
Topics: Anesthetics, Local; Corneal Injuries; Eye Injuries; Eye Pain; Female; Humans; Male; Tetracaine | 2014 |
Good study design, but flawed conclusion in emergency department tetracaine use.
Topics: Anesthetics, Local; Corneal Injuries; Eye Injuries; Eye Pain; Female; Humans; Male; Tetracaine | 2014 |
Good study design, but flawed conclusion in emergency department tetracaine use. In reply.
Topics: Anesthetics, Local; Corneal Injuries; Eye Injuries; Eye Pain; Female; Humans; Male; Tetracaine | 2014 |
Pain assessment in premature infants treated with intravitreal antiangiogenic therapy for retinopathy of prematurity under topical anesthesia.
Topics: Anesthesia, Local; Anesthetics, Local; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; B | 2013 |