tetracaine has been researched along with Erythema in 8 studies
Tetracaine: A potent local anesthetic of the ester type used for surface and spinal anesthesia.
tetracaine : A benzoate ester in which 4-N-butylbenzoic acid and 2-(dimethylamino)ethanol have combined to form the ester bond; a local ester anaesthetic (ester caine) used for surface and spinal anaesthesia.
Erythema: Redness of the skin produced by congestion of the capillaries. This condition may result from a variety of disease processes.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Tetracaine 4% when applied for 30 minutes was not beneficial in decreasing procedural pain associated with a PICC in very small infants." | 9.12 | How effective is tetracaine 4% gel, before a peripherally inserted central catheter, in reducing procedural pain in infants: a randomized double-blind placebo controlled trial [ISRCTN75884221]. ( Blanchard, C; Gaboury, I; Hogan, D; Lemyre, B; Moher, D; Sherlock, R, 2006) |
| "Tetracaine 4% when applied for 30 minutes was not beneficial in decreasing procedural pain associated with a PICC in very small infants." | 5.12 | How effective is tetracaine 4% gel, before a peripherally inserted central catheter, in reducing procedural pain in infants: a randomized double-blind placebo controlled trial [ISRCTN75884221]. ( Blanchard, C; Gaboury, I; Hogan, D; Lemyre, B; Moher, D; Sherlock, R, 2006) |
| "A chart review was performed and patients who presented with erythema of face, neck, chest, and extremities pretreated with topical anesthesia (23% lidocaine/7% tetracaine ointment or 7% lidocaine/7% tetracaine ointment) undergoing PDL were reviewed and compared with another group without anesthesia." | 3.96 | The Efficacy of Pulsed Dye Laser Pretreated With or Without Local Anesthetic on Patients Presenting With Erythema of Face, Neck, Chest, and Extremities. ( Alhaddad, M; Boen, M; Chunharas, C; Wu, DC, 2020) |
| "Chlorpromazine was used as a model drug irritant." | 1.30 | Reverse iontophoresis: monitoring prostaglandin E2 associated with cutaneous inflammation in vivo. ( Buttery, M; Cormier, M; Daddona, P; Mize, NK; Morales, C, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Chunharas, C | 1 |
| Boen, M | 1 |
| Alhaddad, M | 1 |
| Wu, DC | 1 |
| Matos-Pires, E | 1 |
| Pina-Trincão, D | 1 |
| Brás, S | 1 |
| Lobo, L | 1 |
| Reece, A | 1 |
| Burridge, R | 1 |
| Lemyre, B | 1 |
| Sherlock, R | 1 |
| Hogan, D | 1 |
| Gaboury, I | 1 |
| Blanchard, C | 1 |
| Moher, D | 1 |
| Ogden, L | 1 |
| Love, G | 1 |
| Basta, S | 1 |
| Lawson, RA | 1 |
| Smart, NG | 1 |
| Gudgeon, AC | 1 |
| Morton, NS | 1 |
| Mize, NK | 1 |
| Buttery, M | 1 |
| Daddona, P | 1 |
| Morales, C | 1 |
| Cormier, M | 1 |
| Wongprasartsuk, P | 1 |
| Main, BJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Comparison of Amethocaine Creams Versus Liposomal Lidocaine Cream as Pain Reliever Prior to Venipuncture in Children at the Paediatric Emergency Department.[NCT00353002] | 0 participants (Actual) | Interventional | 2006-07-31 | Withdrawn | |||
| The Efficacy of the Eutectic Mixture of Local Anesthetics (EMLA) Cream Versus the Synera Patch for Pain Reduction During Venipuncture in Children[NCT00530803] | Phase 2 | 100 participants (Actual) | Interventional | 2007-06-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The NRS (Numerical Rating Scale) is a 6-point rating scale where 0= no pain and 5 = worst pain. Blinded observers reported their own subjective evaluation of the level of pain experienced by the participants at tourniquet placement. Total number of participants subjectively evaluated as experiencing each pain level is reported. (NCT00530803)
Timeframe: before venipuncture
| Intervention | Participants (Count of Participants) | |||||
|---|---|---|---|---|---|---|
| Participants evaluated at NRS = 0 (No pain) | Participants evaluated at NRS = 1 | Participants evaluated at NRS = 2 | Participants evaluated at NRS = 3 | Participants evaluated at NRS = 4 | Participants evaluated at NRS = 5 | |
| EMLA Cream | 41 | 6 | 2 | 1 | 0 | 0 |
| Synera Patch | 37 | 6 | 5 | 1 | 1 | 0 |
The NRS (Numerical Rating Scale) is a 6-point rating scale where 0= no pain and 5 = worst pain. Blinded observers reported their own subjective evaluation of the level of pain participants were experiencing 5 minutes after the venipuncture was completed. Total number of participants subjectively evaluated as experiencing each pain level is reported. (NCT00530803)
Timeframe: 5 minutes post venipuncture
| Intervention | Participants (Count of Participants) | |||||
|---|---|---|---|---|---|---|
| Participants evaluated at NRS = 0 (No pain) | Participants evaluated at NRS = 1 | Participants evaluated at NRS = 2 | Participants evaluated at NRS = 3 | Participants evaluated at NRS = 4 | Participants evaluated at NRS = 5 | |
| EMLA Cream | 45 | 3 | 1 | 1 | 0 | 0 |
| Synera Patch | 45 | 4 | 1 | 0 | 0 | 0 |
The NRS (Numerical Rating Scale) is a 6-point rating scale where 0= no pain and 5 = worst pain. Blinded observers reported their own subjective evaluation of the level of pain experienced by the participants at needle insertion. Total number of participants subjectively evaluated as experiencing each pain level is reported. (NCT00530803)
Timeframe: during needle insertion
| Intervention | Participants (Count of Participants) | |||||
|---|---|---|---|---|---|---|
| Participants evaluated at NRS = 0 (No pain) | Participants evaluated at NRS = 1 | Participants evaluated at NRS = 2 | Participants evaluated at NRS = 3 | Participants evaluated at NRS = 4 | Participants evaluated at NRS = 5 | |
| EMLA Cream | 32 | 14 | 2 | 2 | 0 | 0 |
| Synera Patch | 25 | 12 | 9 | 2 | 2 | 0 |
The Numerical Rating Scale (NRS) is a 6-point rating scale where 0= no pain and 5 = worst pain. Parents reported their own subjective evaluation of participants pain level. Each participant had only one parental assessment. Total number of parental assessment for each pain level on the 6-point NRS is reported as total number of participants experiencing that pain level. (NCT00530803)
Timeframe: immediately after venipuncture is completed
| Intervention | Participants (Count of Participants) | |||||
|---|---|---|---|---|---|---|
| number of participants with NRS=0 (no pain) | number of participants with NRS=1 | number of participants with NRS=2 | number of participants with NRS=3 | number of participants with NRS=4 | number of participants with NRS=5 | |
| EMLA Cream | 42 | 6 | 1 | 1 | 0 | 0 |
| Synera Patch | 41 | 5 | 1 | 2 | 0 | 1 |
"Participants were asked to report their level of pain using a 6-point Wong-Baker FACES Pain Rating Scale ranging from 0, no pain, to 5, the most pain you can have. The Wong-Baker FACES Pain Rating Scale is a validated tool for measuring pain in patients as young as 3 years old. A FACES pain score less than or equal to 2 is considered no pain to mild pain, and is clinically acceptable. Studies have shown average FACES pain scores for children receiving vascular access with placebo to be 2.2 to 3.5." (NCT00530803)
Timeframe: immediately after completion of venipuncture
| Intervention | Participants (Count of Participants) | |||||
|---|---|---|---|---|---|---|
| Participants with FACES Score = 0 (No pain) | Participants with FACES Score = 1 | Participants with FACES Score = 2 | Participants with FACES Score = 3 | Participants with FACES Score = 4 | Participants with FACES Score = 5 | |
| EMLA Cream | 42 | 6 | 2 | 0 | 0 | 0 |
| Synera Patch | 38 | 8 | 3 | 1 | 0 | 0 |
3 trials available for tetracaine and Erythema
| Article | Year |
|---|---|
How effective is tetracaine 4% gel, before a peripherally inserted central catheter, in reducing procedural pain in infants: a randomized double-blind placebo controlled trial [ISRCTN75884221].
Topics: Administration, Topical; Anesthetics, Local; Catheterization, Central Venous; Double-Blind Method; E | 2006 |
Systemic exposure to lidocaine and tetracaine is low after an application of a lidocaine 7%-tetracaine 7% peel in adults.
Topics: Administration, Topical; Adult; Anesthetics, Local; Area Under Curve; Drug Combinations; Erythema; F | 2008 |
Evaluation of an amethocaine gel preparation for percutaneous analgesia before venous cannulation in children.
Topics: Administration, Cutaneous; Anesthetics, Local; Catheterization, Peripheral; Child; Child, Preschool; | 1995 |
Evaluation of an amethocaine gel preparation for percutaneous analgesia before venous cannulation in children.
Topics: Administration, Cutaneous; Anesthetics, Local; Catheterization, Peripheral; Child; Child, Preschool; | 1995 |
Evaluation of an amethocaine gel preparation for percutaneous analgesia before venous cannulation in children.
Topics: Administration, Cutaneous; Anesthetics, Local; Catheterization, Peripheral; Child; Child, Preschool; | 1995 |
Evaluation of an amethocaine gel preparation for percutaneous analgesia before venous cannulation in children.
Topics: Administration, Cutaneous; Anesthetics, Local; Catheterization, Peripheral; Child; Child, Preschool; | 1995 |
5 other studies available for tetracaine and Erythema
| Article | Year |
|---|---|
The Efficacy of Pulsed Dye Laser Pretreated With or Without Local Anesthetic on Patients Presenting With Erythema of Face, Neck, Chest, and Extremities.
Topics: Adult; Anesthetics, Local; Erythema; Female; Humans; Lasers, Dye; Lidocaine; Low-Level Light Therapy | 2020 |
Baboon syndrome caused by anti-haemorrhoidal ointment.
Topics: Anesthetics, Local; Buttocks; Dermatitis, Allergic Contact; Dibucaine; Erythema; Hemorrhoids; Humans | 2018 |
Images in paediatrics: an unusual reaction to topical amethocaine (Ametop) local anaesthetic gel.
Topics: Administration, Cutaneous; Anesthetics, Local; Child, Preschool; Erythema; Gels; Humans; Male; Skin; | 2012 |
Reverse iontophoresis: monitoring prostaglandin E2 associated with cutaneous inflammation in vivo.
Topics: Amebicides; Anesthetics, Local; Animals; Antiemetics; Arginine Vasopressin; Biological Transport; Bl | 1997 |
Adverse local reactions to amethocaine cream--audit and case reports.
Topics: Administration, Topical; Anesthetics, Local; Child, Preschool; Erythema; Humans; Incidence; Male; Me | 1998 |