tetracaine has been researched along with Disease Models, Animal in 10 studies
Tetracaine: A potent local anesthetic of the ester type used for surface and spinal anesthesia.
tetracaine : A benzoate ester in which 4-N-butylbenzoic acid and 2-(dimethylamino)ethanol have combined to form the ester bond; a local ester anaesthetic (ester caine) used for surface and spinal anaesthesia.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Both 27 and 48 demonstrated robust activity in the acute rat monoiodoacetate-induced osteoarthritis model of pain, and subchronic dosing of 48 showed a shift to a lower EC50 over 7 days." | 5.43 | Substituted Indazoles as Nav1.7 Blockers for the Treatment of Pain. ( Daanen, JF; DeGoey, DA; El-Kouhen, OF; Fricano, MM; Frost, JM; Ghoreishi-Haack, N; Gum, RJ; Hsieh, GC; Kort, ME; Lundgaard, GL; Matulenko, MA; Neelands, T; Pai, M; Shi, L; Zhan, C; Zhang, XF, 2016) |
| " Both 27 and 48 demonstrated robust activity in the acute rat monoiodoacetate-induced osteoarthritis model of pain, and subchronic dosing of 48 showed a shift to a lower EC50 over 7 days." | 1.43 | Substituted Indazoles as Nav1.7 Blockers for the Treatment of Pain. ( Daanen, JF; DeGoey, DA; El-Kouhen, OF; Fricano, MM; Frost, JM; Ghoreishi-Haack, N; Gum, RJ; Hsieh, GC; Kort, ME; Lundgaard, GL; Matulenko, MA; Neelands, T; Pai, M; Shi, L; Zhan, C; Zhang, XF, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (10.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 5 (50.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Frost, JM | 1 |
| DeGoey, DA | 1 |
| Shi, L | 1 |
| Gum, RJ | 1 |
| Fricano, MM | 1 |
| Lundgaard, GL | 1 |
| El-Kouhen, OF | 1 |
| Hsieh, GC | 1 |
| Neelands, T | 1 |
| Matulenko, MA | 1 |
| Daanen, JF | 1 |
| Pai, M | 1 |
| Ghoreishi-Haack, N | 1 |
| Zhan, C | 1 |
| Zhang, XF | 1 |
| Kort, ME | 1 |
| Teng, M | 1 |
| Wu, W | 1 |
| Li, Z | 1 |
| Yang, G | 1 |
| Qin, J | 1 |
| Wang, Y | 1 |
| Hu, Z | 1 |
| Dong, H | 1 |
| Hou, L | 1 |
| Hu, G | 1 |
| Shen, L | 1 |
| Zhang, Y | 1 |
| Li, J | 1 |
| Chen, S | 1 |
| Tian, J | 1 |
| Ye, L | 1 |
| Zhang, J | 1 |
| Wang, H | 1 |
| Solinski, HJ | 1 |
| Dranchak, P | 1 |
| Oliphant, E | 1 |
| Gu, X | 1 |
| Earnest, TW | 1 |
| Braisted, J | 1 |
| Inglese, J | 1 |
| Hoon, MA | 1 |
| Abrams, RPM | 1 |
| Yasgar, A | 1 |
| Teramoto, T | 1 |
| Lee, MH | 1 |
| Dorjsuren, D | 1 |
| Eastman, RT | 1 |
| Malik, N | 1 |
| Zakharov, AV | 1 |
| Li, W | 1 |
| Bachani, M | 1 |
| Brimacombe, K | 1 |
| Steiner, JP | 1 |
| Hall, MD | 1 |
| Balasubramanian, A | 1 |
| Jadhav, A | 1 |
| Padmanabhan, R | 1 |
| Simeonov, A | 1 |
| Nath, A | 1 |
| Sarchahi, AA | 1 |
| Eskandari, M | 1 |
| Hirose, M | 1 |
| Stuyvers, BD | 1 |
| Dun, W | 1 |
| ter Keurs, HE | 1 |
| Boyden, PA | 1 |
| Kojima, A | 1 |
| Kitagawa, H | 1 |
| Omatsu-Kanbe, M | 1 |
| Matsuura, H | 1 |
| Nosaka, S | 1 |
| Johnson, ME | 1 |
| Fitzsimmons, TD | 1 |
| Fagerholm, P | 1 |
| Haler, D | 1 |
1 review available for tetracaine and Disease Models, Animal
| Article | Year |
|---|---|
Potential neurotoxicity of spinal anesthesia with lidocaine.
Topics: Adverse Drug Reaction Reporting Systems; Anesthesia, Spinal; Anesthetics, Local; Animals; Bupivacain | 2000 |
9 other studies available for tetracaine and Disease Models, Animal
| Article | Year |
|---|---|
Substituted Indazoles as Nav1.7 Blockers for the Treatment of Pain.
Topics: Analgesics; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Electrophysiology; Ev | 2016 |
Discovery of aminocyclohexene analogues as selective and orally bioavailable hNav1.7 inhibitors for analgesia.
Topics: Administration, Oral; Analgesics; Animals; Binding Sites; Cyclohexenes; Cytochrome P-450 CYP2C9; Dis | 2017 |
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S | 2019 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
Effect of four local anesthetics (tetracaine, proparacaine, lidocaine, and bupivacaine) on intraocular pressure in dogs.
Topics: Administration, Topical; Anesthesia, Local; Anesthetics, Local; Animals; Bupivacaine; Disease Models | 2019 |
Function of Ca(2+) release channels in Purkinje cells that survive in the infarcted canine heart: a mechanism for triggered Purkinje ectopy.
Topics: Animals; Arrhythmias, Cardiac; Caffeine; Calcium Channels; Calcium Signaling; Cell Survival; Disease | 2008 |
Ca2+ paradox injury mediated through TRPC channels in mouse ventricular myocytes.
Topics: Animals; Caffeine; Calcium; Disease Models, Animal; Heart Injuries; Heart Ventricles; Membrane Poten | 2010 |
Superficial keratectomy with the 193 nm excimer laser: a reproducible model of corneal surface irregularities.
Topics: Animals; Cornea; Corneal Diseases; Disease Models, Animal; Hyaluronic Acid; Hypromellose Derivatives | 1991 |
The effect of "Noxyflex" (Noxytioline) on the behaviour of animals which have been infected intraperitoneally with suspensions of faeces.
Topics: Animals; Anti-Infective Agents; Behavior, Animal; Disease Models, Animal; Feces; Injections, Intrape | 1974 |