tetracaine has been researched along with Corneal Injuries in 17 studies
Tetracaine: A potent local anesthetic of the ester type used for surface and spinal anesthesia.
tetracaine : A benzoate ester in which 4-N-butylbenzoic acid and 2-(dimethylamino)ethanol have combined to form the ester bond; a local ester anaesthetic (ester caine) used for surface and spinal anaesthesia.
Corneal Injuries: Damage or trauma inflicted to the CORNEA by external means.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The objective of this study was to test the hypothesis that topical tetracaine would be safe to use for 24 hours and would not affect corneal healing, that patients would experience more pain relief, and that patients would perceive tetracaine to be more effective than saline eye drops for the treatment of pain caused by corneal abrasions." | 2.79 | Topical tetracaine used for 24 hours is safe and rated highly effective by patients for the treatment of pain caused by corneal abrasions: a double-blind, randomized clinical trial. ( Densie, IK; Herbison, P; Waldman, N, 2014) |
| " All six studies demonstrated that a short course of dilute topical anesthetic provided efficacious analgesia without adverse effects or delayed epithelial healing." | 2.52 | The Safety of Topical Anesthetics in the Treatment of Corneal Abrasions: A Review. ( Milne, K; Otterness, K; Rezaie, S; Swaminathan, A, 2015) |
| "Although treating pain is associated with improved quality of life, most respondents did not support TA use in the ED." | 1.91 | Topical Anesthetics for Analgesia in Acute Corneal Abrasion: Eye Care Providers Survey. ( Anderson-Quiñones, C; Asbell, P; Tolley, EA; Vestal, R; Zhu, R, 2023) |
| "Tetracaine was dispensed at the initial visit for 303 SCA presentations (57%) and inappropriately for 141 NSCA presentations (14%)." | 1.48 | An Observational Study to Determine Whether Routinely Sending Patients Home With a 24-Hour Supply of Topical Tetracaine From the Emergency Department for Simple Corneal Abrasion Pain Is Potentially Safe. ( Densie, I; Giddings, G; Gray, A; McMaster, S; Meanley, J; Waldman, N; Winrow, B, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (23.53) | 18.7374 |
| 1990's | 3 (17.65) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 8 (47.06) | 24.3611 |
| 2020's | 2 (11.76) | 2.80 |
| Authors | Studies |
|---|---|
| Anderson-Quiñones, C | 1 |
| Zhu, R | 1 |
| Tolley, EA | 1 |
| Vestal, R | 1 |
| Asbell, P | 1 |
| Shipman, S | 1 |
| Painter, K | 1 |
| Keuchel, M | 1 |
| Bogie, C | 1 |
| Waldman, N | 4 |
| Winrow, B | 1 |
| Densie, I | 1 |
| Gray, A | 1 |
| McMaster, S | 1 |
| Giddings, G | 1 |
| Meanley, J | 1 |
| Densie, IK | 3 |
| Herbison, P | 2 |
| Ufberg, JW | 1 |
| Karras, DJ | 1 |
| Pruet, CM | 1 |
| Feldman, RM | 1 |
| Kim, G | 1 |
| Tijunelis, M | 1 |
| Tozer, K | 1 |
| Swaminathan, A | 1 |
| Otterness, K | 1 |
| Milne, K | 1 |
| Rezaie, S | 1 |
| SCHMOGER, E | 1 |
| Dunnet, SR | 1 |
| MacKinnon, G | 1 |
| Rocha, G | 1 |
| Brunette, I | 1 |
| Le François, M | 1 |
| Chern, KC | 1 |
| Meisler, DM | 1 |
| Wilhelmus, KR | 1 |
| Jones, DB | 1 |
| Stern, GA | 1 |
| Lowder, CY | 1 |
| Epstein, DL | 1 |
| Paton, D | 1 |
| Bykov, NF | 1 |
| Semenova, DI | 1 |
| Sheldon, GM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Short Term Topical Tetracaine is Safe and Highly Efficacious for the Treatment of Pain Caused by Corneal Abrasions: a Double-blind Randomized Clinical Trial[NCT04187417] | 118 participants (Actual) | Interventional | 2015-01-01 | Completed | |||
| Treatment of Corneal Abrasions With Topical Tetracaine: an Evaluation of Safety and Efficacy[NCT02771392] | Phase 2/Phase 3 | 120 participants (Anticipated) | Interventional | 2016-06-30 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for tetracaine and Corneal Injuries
| Article | Year |
|---|---|
The Safety of Topical Anesthetics in the Treatment of Corneal Abrasions: A Review.
Topics: Anesthetics, Local; Corneal Injuries; Eye Pain; Humans; Propoxycaine; Tetracaine; Wound Healing | 2015 |
2 trials available for tetracaine and Corneal Injuries
| Article | Year |
|---|---|
Short-Term Topical Tetracaine Is Highly Efficacious for the Treatment of Pain Caused by Corneal Abrasions: A Double-Blind, Randomized Clinical Trial.
Topics: Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics; Corneal Injuries; D | 2021 |
Topical tetracaine used for 24 hours is safe and rated highly effective by patients for the treatment of pain caused by corneal abrasions: a double-blind, randomized clinical trial.
Topics: Administration, Ophthalmic; Adolescent; Adult; Aged; Anesthetics, Local; Cornea; Corneal Injuries; D | 2014 |
Topical tetracaine used for 24 hours is safe and rated highly effective by patients for the treatment of pain caused by corneal abrasions: a double-blind, randomized clinical trial.
Topics: Administration, Ophthalmic; Adolescent; Adult; Aged; Anesthetics, Local; Cornea; Corneal Injuries; D | 2014 |
Topical tetracaine used for 24 hours is safe and rated highly effective by patients for the treatment of pain caused by corneal abrasions: a double-blind, randomized clinical trial.
Topics: Administration, Ophthalmic; Adolescent; Adult; Aged; Anesthetics, Local; Cornea; Corneal Injuries; D | 2014 |
Topical tetracaine used for 24 hours is safe and rated highly effective by patients for the treatment of pain caused by corneal abrasions: a double-blind, randomized clinical trial.
Topics: Administration, Ophthalmic; Adolescent; Adult; Aged; Anesthetics, Local; Cornea; Corneal Injuries; D | 2014 |
14 other studies available for tetracaine and Corneal Injuries
| Article | Year |
|---|---|
Topical Anesthetics for Analgesia in Acute Corneal Abrasion: Eye Care Providers Survey.
Topics: Analgesia; Anesthetics, Local; Corneal Injuries; Humans; Pain; Quality of Life; Surveys and Question | 2023 |
An Observational Study to Determine Whether Routinely Sending Patients Home With a 24-Hour Supply of Topical Tetracaine From the Emergency Department for Simple Corneal Abrasion Pain Is Potentially Safe.
Topics: Adolescent; Adult; Anesthetics, Local; Corneal Injuries; Drug Administration Schedule; Emergency Ser | 2018 |
Dogma challenged: tetracaine for corneal abrasions?
Topics: Anesthetics, Local; Corneal Injuries; Eye Injuries; Eye Pain; Female; Humans; Male; Tetracaine | 2014 |
Re: "topical tetracaine used for 24 hours is safe and rated highly effective by patients for the treatment of pain caused by corneal abrasions: a double-blind, randomized clinical trial".
Topics: Anesthetics, Local; Corneal Injuries; Eye Injuries; Eye Pain; Female; Humans; Male; Tetracaine | 2014 |
In reply.
Topics: Anesthetics, Local; Corneal Injuries; Eye Injuries; Eye Pain; Female; Humans; Male; Tetracaine | 2014 |
Good study design, but flawed conclusion in emergency department tetracaine use.
Topics: Anesthetics, Local; Corneal Injuries; Eye Injuries; Eye Pain; Female; Humans; Male; Tetracaine | 2014 |
Good study design, but flawed conclusion in emergency department tetracaine use. In reply.
Topics: Anesthetics, Local; Corneal Injuries; Eye Injuries; Eye Pain; Female; Humans; Male; Tetracaine | 2014 |
[Injuries caused by pantocaine administration].
Topics: Anesthetics; Anesthetics, Local; Cornea; Corneal Injuries; Humans; Tetracaine | 1953 |
Inadvertent instillation of Minims eye drops.
Topics: Corneal Injuries; Eye Injuries; Humans; Medication Errors; Mydriatics; Pupil; Tetracaine; Tropanes; | 1995 |
Severe toxic keratopathy secondary to topical anesthetic abuse.
Topics: Administration, Topical; Adult; Anesthetics, Local; Burns, Chemical; Cornea; Corneal Diseases; Corne | 1995 |
Corneal anesthetic abuse and Candida keratitis.
Topics: Administration, Topical; Adult; Anesthetics, Local; Antifungal Agents; Candida albicans; Candidiasis | 1996 |
Keratitis from misuse of corneal anesthetics.
Topics: 4-Aminobenzoic Acid; Adult; Anesthetics, Local; Blindness; Cornea; Corneal Injuries; Eye Injuries; F | 1968 |
[Effect of local anesthetic substances on the reparative regneration of corneal epithelium].
Topics: Anesthetics, Local; Animals; Cocaine; Cornea; Corneal Injuries; Epithelium; Intraocular Pressure; Li | 1972 |
Misuse of corneal anesthetics.
Topics: Accidents; Adolescent; Anesthetics, Local; Corneal Injuries; Corneal Ulcer; Eye Foreign Bodies; Eye | 1971 |