Page last updated: 2024-11-04

tetracaine and Cornea Injuries

tetracaine has been researched along with Cornea Injuries in 17 studies

Tetracaine: A potent local anesthetic of the ester type used for surface and spinal anesthesia.
tetracaine : A benzoate ester in which 4-N-butylbenzoic acid and 2-(dimethylamino)ethanol have combined to form the ester bond; a local ester anaesthetic (ester caine) used for surface and spinal anaesthesia.

Research Excerpts

ExcerptRelevanceReference
"The objective of this study was to test the hypothesis that topical tetracaine would be safe to use for 24 hours and would not affect corneal healing, that patients would experience more pain relief, and that patients would perceive tetracaine to be more effective than saline eye drops for the treatment of pain caused by corneal abrasions."2.79Topical tetracaine used for 24 hours is safe and rated highly effective by patients for the treatment of pain caused by corneal abrasions: a double-blind, randomized clinical trial. ( Densie, IK; Herbison, P; Waldman, N, 2014)
" All six studies demonstrated that a short course of dilute topical anesthetic provided efficacious analgesia without adverse effects or delayed epithelial healing."2.52The Safety of Topical Anesthetics in the Treatment of Corneal Abrasions: A Review. ( Milne, K; Otterness, K; Rezaie, S; Swaminathan, A, 2015)
"Although treating pain is associated with improved quality of life, most respondents did not support TA use in the ED."1.91Topical Anesthetics for Analgesia in Acute Corneal Abrasion: Eye Care Providers Survey. ( Anderson-Quiñones, C; Asbell, P; Tolley, EA; Vestal, R; Zhu, R, 2023)
"Tetracaine was dispensed at the initial visit for 303 SCA presentations (57%) and inappropriately for 141 NSCA presentations (14%)."1.48An Observational Study to Determine Whether Routinely Sending Patients Home With a 24-Hour Supply of Topical Tetracaine From the Emergency Department for Simple Corneal Abrasion Pain Is Potentially Safe. ( Densie, I; Giddings, G; Gray, A; McMaster, S; Meanley, J; Waldman, N; Winrow, B, 2018)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19904 (23.53)18.7374
1990's3 (17.65)18.2507
2000's0 (0.00)29.6817
2010's8 (47.06)24.3611
2020's2 (11.76)2.80

Authors

AuthorsStudies
Anderson-Quiñones, C1
Zhu, R1
Tolley, EA1
Vestal, R1
Asbell, P1
Shipman, S1
Painter, K1
Keuchel, M1
Bogie, C1
Waldman, N4
Winrow, B1
Densie, I1
Gray, A1
McMaster, S1
Giddings, G1
Meanley, J1
Densie, IK3
Herbison, P2
Ufberg, JW1
Karras, DJ1
Pruet, CM1
Feldman, RM1
Kim, G1
Tijunelis, M1
Tozer, K1
Swaminathan, A1
Otterness, K1
Milne, K1
Rezaie, S1
SCHMOGER, E1
Dunnet, SR1
MacKinnon, G1
Rocha, G1
Brunette, I1
Le François, M1
Chern, KC1
Meisler, DM1
Wilhelmus, KR1
Jones, DB1
Stern, GA1
Lowder, CY1
Epstein, DL1
Paton, D1
Bykov, NF1
Semenova, DI1
Sheldon, GM1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Short Term Topical Tetracaine is Safe and Highly Efficacious for the Treatment of Pain Caused by Corneal Abrasions: a Double-blind Randomized Clinical Trial[NCT04187417]118 participants (Actual)Interventional2015-01-01Completed
Treatment of Corneal Abrasions With Topical Tetracaine: an Evaluation of Safety and Efficacy[NCT02771392]Phase 2/Phase 3120 participants (Anticipated)Interventional2016-06-30Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for tetracaine and Cornea Injuries

ArticleYear
The Safety of Topical Anesthetics in the Treatment of Corneal Abrasions: A Review.
    The Journal of emergency medicine, 2015, Volume: 49, Issue:5

    Topics: Anesthetics, Local; Corneal Injuries; Eye Pain; Humans; Propoxycaine; Tetracaine; Wound Healing

2015

Trials

2 trials available for tetracaine and Cornea Injuries

ArticleYear
Short-Term Topical Tetracaine Is Highly Efficacious for the Treatment of Pain Caused by Corneal Abrasions: A Double-Blind, Randomized Clinical Trial.
    Annals of emergency medicine, 2021, Volume: 77, Issue:3

    Topics: Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics; Corneal Injuries; D

2021
Topical tetracaine used for 24 hours is safe and rated highly effective by patients for the treatment of pain caused by corneal abrasions: a double-blind, randomized clinical trial.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2014, Volume: 21, Issue:4

    Topics: Administration, Ophthalmic; Adolescent; Adult; Aged; Anesthetics, Local; Cornea; Corneal Injuries; D

2014
Topical tetracaine used for 24 hours is safe and rated highly effective by patients for the treatment of pain caused by corneal abrasions: a double-blind, randomized clinical trial.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2014, Volume: 21, Issue:4

    Topics: Administration, Ophthalmic; Adolescent; Adult; Aged; Anesthetics, Local; Cornea; Corneal Injuries; D

2014
Topical tetracaine used for 24 hours is safe and rated highly effective by patients for the treatment of pain caused by corneal abrasions: a double-blind, randomized clinical trial.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2014, Volume: 21, Issue:4

    Topics: Administration, Ophthalmic; Adolescent; Adult; Aged; Anesthetics, Local; Cornea; Corneal Injuries; D

2014
Topical tetracaine used for 24 hours is safe and rated highly effective by patients for the treatment of pain caused by corneal abrasions: a double-blind, randomized clinical trial.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2014, Volume: 21, Issue:4

    Topics: Administration, Ophthalmic; Adolescent; Adult; Aged; Anesthetics, Local; Cornea; Corneal Injuries; D

2014

Other Studies

14 other studies available for tetracaine and Cornea Injuries

ArticleYear
Topical Anesthetics for Analgesia in Acute Corneal Abrasion: Eye Care Providers Survey.
    Eye & contact lens, 2023, Apr-01, Volume: 49, Issue:4

    Topics: Analgesia; Anesthetics, Local; Corneal Injuries; Humans; Pain; Quality of Life; Surveys and Question

2023
An Observational Study to Determine Whether Routinely Sending Patients Home With a 24-Hour Supply of Topical Tetracaine From the Emergency Department for Simple Corneal Abrasion Pain Is Potentially Safe.
    Annals of emergency medicine, 2018, Volume: 71, Issue:6

    Topics: Adolescent; Adult; Anesthetics, Local; Corneal Injuries; Drug Administration Schedule; Emergency Ser

2018
Dogma challenged: tetracaine for corneal abrasions?
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2014, Volume: 21, Issue:4

    Topics: Anesthetics, Local; Corneal Injuries; Eye Injuries; Eye Pain; Female; Humans; Male; Tetracaine

2014
Re: "topical tetracaine used for 24 hours is safe and rated highly effective by patients for the treatment of pain caused by corneal abrasions: a double-blind, randomized clinical trial".
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2014, Volume: 21, Issue:9

    Topics: Anesthetics, Local; Corneal Injuries; Eye Injuries; Eye Pain; Female; Humans; Male; Tetracaine

2014
In reply.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2014, Volume: 21, Issue:9

    Topics: Anesthetics, Local; Corneal Injuries; Eye Injuries; Eye Pain; Female; Humans; Male; Tetracaine

2014
Good study design, but flawed conclusion in emergency department tetracaine use.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2014, Volume: 21, Issue:11

    Topics: Anesthetics, Local; Corneal Injuries; Eye Injuries; Eye Pain; Female; Humans; Male; Tetracaine

2014
Good study design, but flawed conclusion in emergency department tetracaine use. In reply.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2014, Volume: 21, Issue:11

    Topics: Anesthetics, Local; Corneal Injuries; Eye Injuries; Eye Pain; Female; Humans; Male; Tetracaine

2014
[Injuries caused by pantocaine administration].
    Klinische Monatsblatter fur Augenheilkunde und fur augenarztliche Fortbildung, 1953, Volume: 122, Issue:5

    Topics: Anesthetics; Anesthetics, Local; Cornea; Corneal Injuries; Humans; Tetracaine

1953
Inadvertent instillation of Minims eye drops.
    Acta ophthalmologica Scandinavica, 1995, Volume: 73, Issue:3

    Topics: Corneal Injuries; Eye Injuries; Humans; Medication Errors; Mydriatics; Pupil; Tetracaine; Tropanes;

1995
Severe toxic keratopathy secondary to topical anesthetic abuse.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 1995, Volume: 30, Issue:4

    Topics: Administration, Topical; Adult; Anesthetics, Local; Burns, Chemical; Cornea; Corneal Diseases; Corne

1995
Corneal anesthetic abuse and Candida keratitis.
    Ophthalmology, 1996, Volume: 103, Issue:1

    Topics: Administration, Topical; Adult; Anesthetics, Local; Antifungal Agents; Candida albicans; Candidiasis

1996
Keratitis from misuse of corneal anesthetics.
    The New England journal of medicine, 1968, Aug-22, Volume: 279, Issue:8

    Topics: 4-Aminobenzoic Acid; Adult; Anesthetics, Local; Blindness; Cornea; Corneal Injuries; Eye Injuries; F

1968
[Effect of local anesthetic substances on the reparative regneration of corneal epithelium].
    Oftalmologicheskii zhurnal, 1972, Volume: 27, Issue:3

    Topics: Anesthetics, Local; Animals; Cocaine; Cornea; Corneal Injuries; Epithelium; Intraocular Pressure; Li

1972
Misuse of corneal anesthetics.
    Canadian Medical Association journal, 1971, Mar-20, Volume: 104, Issue:6

    Topics: Accidents; Adolescent; Anesthetics, Local; Corneal Injuries; Corneal Ulcer; Eye Foreign Bodies; Eye

1971