Page last updated: 2024-11-04

tetracaine and Complication, Intraoperative

tetracaine has been researched along with Complication, Intraoperative in 18 studies

Tetracaine: A potent local anesthetic of the ester type used for surface and spinal anesthesia.
tetracaine : A benzoate ester in which 4-N-butylbenzoic acid and 2-(dimethylamino)ethanol have combined to form the ester bond; a local ester anaesthetic (ester caine) used for surface and spinal anaesthesia.

Research Excerpts

ExcerptRelevanceReference
"To report the occurrence of apnea and bradycardia in two former pre-term infants who received spinal anaesthesia without inhalational or intravenous anaesthetic agents during inguinal herniorrhaphy."7.70Apnea following spinal anaesthesia in two former pre-term infants. ( Burd, RS; Helikson, MA; Tobias, JD, 1998)
"Of 15 tetracaine-treated neonates, 14 (93%) presented little or no pain in response to the procedure compared with six of 17 (35%) who had the placebo patch applied (P=0."5.10Randomized trial of novel tetracaine patch to provide local anaesthesia in neonates undergoing venepuncture. ( Halliday, HL; Jones, DS; Long, CP; McCafferty, DF; Sittlington, NM; Woolfson, AD, 2003)
"To report the occurrence of apnea and bradycardia in two former pre-term infants who received spinal anaesthesia without inhalational or intravenous anaesthetic agents during inguinal herniorrhaphy."3.70Apnea following spinal anaesthesia in two former pre-term infants. ( Burd, RS; Helikson, MA; Tobias, JD, 1998)
" Therefore, we undertook a dose-response study of hypobaric tetracaine for THR."2.71Hypobaric spinal anesthesia with 0.2% tetracaine for total joint hip arthroplasy. ( Ahn, HJ; Kim, JA, 2005)
"The current study was conducted to determine whether topical anesthesia with oral sedation and without an anesthetist present in the operating room is a safe and cost-effective strategy for low-risk patients undergoing cataract surgery."1.34Safety of cataract surgery under topical anesthesia with oral sedation without anesthetic monitoring. ( Rocha, G; Turner, C, 2007)
"Tetracaine alone was effective in providing tympanic membrane anesthesia in 95% of myringotomy without a tube (220 ears) and in 93% of myringotomy with a tube (139 ears)."1.31Tetracaine topical anesthesia for myringotomy. ( Hoffman, RA; Li, CL, 2001)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (38.89)18.2507
2000's9 (50.00)29.6817
2010's2 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bellini, LP1
Brum, GS1
Grossi, RS1
Borowsky, C1
Kaluzny, BJ1
Kazmierczak, K1
Laudencka, A1
Eliks, I1
Kaluzny, JJ1
Shah, NV1
Vaddavalli, PK1
Chow, JH1
Roman, JS1
Shi, W1
Yoo, SH1
Long, CP1
McCafferty, DF1
Sittlington, NM1
Halliday, HL1
Woolfson, AD1
Jones, DS1
Irle, S1
Lückefahr, MH1
Tomalla, M1
Kim, JA1
Ahn, HJ1
Rocha, G1
Turner, C1
Weinberg, G1
VadeBoncouer, T1
Shaw, AD1
Ang, GS1
Eke, T1
Hirabayashi, Y1
Saitoh, K1
Fukuda, H1
Shimizu, R1
Fairfield, MC1
Lebuisson, DA1
Lim, P1
Mary, JC1
Jolivet, MC1
Roux, L1
Rigal-Sastourné, JC1
Bidaux, F1
May, F1
Renard, JP1
Maurin, JF1
Tobias, JD1
Burd, RS1
Helikson, MA1
Tetzlaff, JE1
Dilger, JA1
Kodsy, M1
al-Bataineh, J1
Yoon, HJ1
Bell, GR1
Faberowski, LW1
Mahla, ME1
Gravenstein, N1
Mönestam, E1
Kuusik, M1
Wachtmeister, L1
Hoffman, RA1
Li, CL1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Prospective Randomized Controlled Clinical Trial Comparing the Intra-operative Effects, Safety, Efficacy and Performance of Two Commercially Available Laser Systems in Patients Undergoing Femtosecond Laser-Assisted Cataract Surgery.[NCT01878838]45 participants (Actual)Interventional2013-04-30Completed
Comparison of 0.5% Tetracaine Drops Versus 2% Lidocaine Gel for Anesthetic Efficacy and Comfort in Patients Undergoing LASIK[NCT01383200]Phase 411 participants (Actual)Interventional2011-06-30Terminated (stopped due to eyes that received gel had slightly thinner than intended flaps)
Comparative Analysis of Oral Sedation Versus Standard Intravenous Sedation in Vitreoretinal Surgery With Topical Anesthesia and Sub-tenon's Block[NCT04346095]Phase 480 participants (Anticipated)Interventional2020-06-30Not yet recruiting
Comparing Topical Tetracaine Drops to Topical Focal Phenol for Local Anesthesia During Intratympanic Steroid Injection[NCT04794842]Early Phase 180 participants (Actual)Interventional2021-08-01Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Participants Score on Pain Scale

Do you have sharp pain in your eye? Pain will be assessed by units on a scale of 1-5: 1 means no symptoms, 2 means slight discomfort, 3 means mild discomfort, 4 means moderate discomfort, and 5 means severe discomfort (NCT01383200)
Timeframe: 1 hour (60minutes) post LASIK operation

InterventionScore on scale (Mean)
Tetracaine1.95
Lidocaine2.01

Trials

6 trials available for tetracaine and Complication, Intraoperative

ArticleYear
Oral acetaminophen (paracetamol) for additional analgesia in phacoemulsification cataract surgery performed using topical anesthesia Randomized double-masked placebo-controlled trial.
    Journal of cataract and refractive surgery, 2010, Volume: 36, Issue:3

    Topics: Acetaminophen; Administration, Oral; Aged; Analgesia; Analgesics, Non-Narcotic; Anesthesia, Local; A

2010
Prospective, double-masked, randomized trial comparing lidocaine gel to tetracaine drops in femtosecond laser-assisted LASIK.
    Journal of refractive surgery (Thorofare, N.J. : 1995), 2012, Volume: 28, Issue:10

    Topics: Anesthetics, Local; Corneal Stroma; Double-Blind Method; Eye Pain; Gels; Humans; Intraoperative Comp

2012
Randomized trial of novel tetracaine patch to provide local anaesthesia in neonates undergoing venepuncture.
    British journal of anaesthesia, 2003, Volume: 91, Issue:4

    Topics: Administration, Cutaneous; Anesthesia, Local; Anesthetics, Local; Double-Blind Method; Female; Human

2003
Hypobaric spinal anesthesia with 0.2% tetracaine for total joint hip arthroplasy.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2005, Volume: 52, Issue:9

    Topics: Adult; Aged; Anesthesia, Spinal; Anesthetics, Local; Arthroplasty, Replacement, Hip; Cross-Over Stud

2005
Visceral pain during caesarean section: effect of varying dose of spinal amethocaine.
    British journal of anaesthesia, 1995, Volume: 75, Issue:3

    Topics: Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Local; Cesarean Section; Double-Bli

1995
[Intracameral lidocaine and phacoemulsification under topical anesthesia. Apropos of 80 operations].
    Journal francais d'ophtalmologie, 1998, Volume: 21, Issue:4

    Topics: Administration, Topical; Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Anterior Ch

1998

Other Studies

12 other studies available for tetracaine and Complication, Intraoperative

ArticleYear
Cataract surgery complication rates.
    Ophthalmology, 2008, Volume: 115, Issue:8

    Topics: Aged; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Local; Anterior Chamber; Humans; Intrao

2008
[Topical anesthesia as routine procedure in cataract surgery -- evaluation of pain and complications in 1010 cases].
    Klinische Monatsblatter fur Augenheilkunde, 2005, Volume: 222, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Local; Anterior Chamber; Female; Humans; Injections; Int

2005
Safety of cataract surgery under topical anesthesia with oral sedation without anesthetic monitoring.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 2007, Volume: 42, Issue:2

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Combined; Anes

2007
Drug interaction or drug overdose? Supercaine revisited.
    Anesthesia and analgesia, 2007, Volume: 105, Issue:2

    Topics: Drug Interactions; Drug Overdose; Heart Arrest; Humans; Intraoperative Complications; Mepivacaine; T

2007
Phacoemulsification complication rates.
    Ophthalmology, 2007, Volume: 114, Issue:11

    Topics: Anesthesia, Local; Anesthetics, Combined; Anesthetics, Local; Anterior Chamber; Humans; Intraoperati

2007
Visceral pain during caesarean section.
    British journal of anaesthesia, 1996, Volume: 76, Issue:1

    Topics: Abdominal Pain; Analgesia, Obstetrical; Anesthetics, Local; Cesarean Section; Female; Humans; Intrao

1996
[Topical anesthesia for cataract surgery in adults].
    Journal francais d'ophtalmologie, 1996, Volume: 19, Issue:3

    Topics: Aged; Aged, 80 and over; Ambulatory Surgical Procedures; Anesthesia, Local; Anesthetics, Local; Cata

1996
Apnea following spinal anaesthesia in two former pre-term infants.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1998, Volume: 45, Issue:10

    Topics: Age Factors; Anesthesia, Spinal; Anesthetics, Local; Apnea; Benzoates; Bradycardia; Caffeine; Centra

1998
Spinal anesthesia for elective lumbar spine surgery.
    Journal of clinical anesthesia, 1998, Volume: 10, Issue:8

    Topics: Anesthesia, General; Anesthesia, Spinal; Anesthetics, Local; Body Height; Body Weight; Bupivacaine;

1998
Spinal anesthesia for nonpulmonary surgery in a lung transplant recipient.
    Journal of neurosurgical anesthesiology, 1999, Volume: 11, Issue:1

    Topics: Anesthesia, Spinal; Anesthetics, Local; Female; Foreign Bodies; Humans; Intraoperative Complications

1999
Topical anesthesia for cataract surgery: a population-based perspective.
    Journal of cataract and refractive surgery, 2001, Volume: 27, Issue:3

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Anesthesia, Local; A

2001
Tetracaine topical anesthesia for myringotomy.
    The Laryngoscope, 2001, Volume: 111, Issue:9

    Topics: Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Ambulatory Surgical Procedures;

2001