Page last updated: 2024-08-21

testolactone and Breast Cancer

testolactone has been researched along with Breast Cancer in 40 studies

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-199039 (97.50)18.7374
1990's1 (2.50)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Janssen, PA; Van Wauwe, JP1
Covey, DF; Hood, WF1
CAU, M; JACOBELLI, G; MARGOTTINI, M1
GORINS, A; NETTER, A1
COUNE, A; SIMON, S; TAGNON, HJ; VANRYMENANT, M1
DEBRIS, P; DELAITRE, R; GABILAN, JC; GERBEAUX, S; HABIB, R; MATHIEU, H; PASQUALINI, JR; RAYNAUD, C; ROYER, P1
BISEL, HF1
Cantino, TJ; Gordan, GS1
Appelgren, LE; Carlström, K; Theve, T; Wallgren, A; Wilking, N1
Feil, PD; Santen, RJ; Santner, SJ; Tilson-Mallett, N1
Segaloff, A2
Sauven, P1
Dao, TL1
Covey, DF; Etre, LA; MacIndoe, JH; Woods, GR1
Barone, RM; Gambone, JC; Judd, HL; Lasley, BL; Laufer, LR; Monfort, SL1
Kaufman, RJ1
Budnick, RM; Dao, TL1
Feldhammer, B; Koldovsky, U; von Matthiessen, H1
Cocconi, G1
Bernardo, G; Robustelli Della Cuna, G; Strada, MR1
Rieche, K; Wolff, G2
Barone, RM; Judd, HL1
Barone, RM; Judd, HL; Shamonki, IM; Siiteri, PK1
Goldenberg, IS; Haines, CR; Kelley, RM; Sedransk, N; Segaloff, A; Volk, H1
Kvinnsland, S; Lönning, PE; Lundgren, S; Wiedemann, G1
Feil, PD; Leszczynski, D; Manni, A; Santen, RJ; Santner, SJ; Tilson-Mallet, N; Wright, C1
Donovan, AJ; Sievers, DB1
Carabasi, RA; Deupree, RH; Escher, GC; Goldenberg, IS; Volk, H; Wilde, RC1
Ansfield, FJ; Goldenberg, IS; Ravdin, RS; Segaloff, A; Waters, N1
Gordan, GS; Halden, A; Horn, Y; Shonfeld, EM; Walter, RM1
Gordan, GS; Halden, A; Horn, Y2
Goldenberg, IS1
Burrows, JH; O'Bryan, RM; San Diego, EL; Talley, RW1
Demol, R1
Carriere, BT; Gabbard, RB; Segaloff, A1

Reviews

3 review(s) available for testolactone and Breast Cancer

ArticleYear
Is there a case for P-450 inhibitors in cancer treatment?
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:10

    Topics: Aminoglutethimide; Aromatase Inhibitors; Breast Neoplasms; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Female; Humans; Ketoconazole; Male; Neoplasms; Prostatic Neoplasms

1989
First generation aromatase inhibitors--aminoglutethimide and testololactone.
    Breast cancer research and treatment, 1994, Volume: 30, Issue:1

    Topics: Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Female; Humans; Hydrocortisone; Randomized Controlled Trials as Topic; Testolactone

1994
Enzymatic control of estrogen production in human breast cancer: relative significance of aromatase versus sulfatase pathways.
    Annals of the New York Academy of Sciences, 1986, Volume: 464

    Topics: 17-Hydroxysteroid Dehydrogenases; Adrenalectomy; Aminoglutethimide; Androstenedione; Animals; Aromatase; Breast Neoplasms; Estradiol; Estrogens; Estrone; Female; Humans; Hydrocortisone; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Rats; Sulfatases; Testolactone

1986

Trials

7 trial(s) available for testolactone and Breast Cancer

ArticleYear
delta 1-testololactone: clinical trials'.
    Cancer research, 1982, Volume: 42, Issue:8 Suppl

    Topics: Aged; Breast Neoplasms; Clinical Trials as Topic; Drug Administration Schedule; Female; Humans; Middle Aged; Random Allocation; Testolactone

1982
[Androgen therapy of incurable breast neoplasms. Controlled clinical study: nandrolone-testololactone-drostanolone].
    Onkologie, 1978, Volume: 1, Issue:4

    Topics: Androstanols; Androstenes; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Evaluation; Female; Humans; Nandrolone; Testolactone; Testosterone Congeners; Virilism

1978
Combined androgen and antimetabolite therapy of advanced female breast cancer. A report of the cooperative breast cancer group.
    Cancer, 1975, Volume: 36, Issue:2

    Topics: Administration, Oral; Breast Neoplasms; Clinical Trials as Topic; Drug Evaluation; Drug Therapy, Combination; Female; Fluorouracil; Humans; Injections, Intravenous; Middle Aged; Neoplasm Metastasis; Testolactone

1975
Comparison of testosterone decanoate, drostanolone and testololactone in disseminated breast cancer--a randomized clinical study.
    Archiv fur Geschwulstforschung, 1975, Volume: 45, Issue:5

    Topics: Adult; Aged; Androstanols; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Humans; Middle Aged; Neoplasm Metastasis; Testolactone; Testosterone

1975
Clinical trial of delta-1-testololactone (NSC 23759), medroxy progesterone acetate (NSC 26386) and oxylone acetate (NSC 47438) in advanced female mammary cancer. A report of the cooperative breast cancer group.
    Cancer, 1969, Volume: 23, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Clinical Trials as Topic; Female; Fluorometholone; Humans; Medroxyprogesterone; Middle Aged; Neoplasm Metastasis; Prognosis; Testolactone

1969
Teslac.
    The Medical letter on drugs and therapeutics, 1970, May-29, Volume: 12, Issue:11

    Topics: Antineoplastic Agents; Breast Neoplasms; Clinical Trials as Topic; Female; Humans; Lactones; Neoplasm Metastasis; Phenanthrenes; Testolactone

1970
Comparison of 1 -testololactone (NSC-23759) and an estrogen-progestin combination (NSC-77622) in the treatment of metastatic breast cancer.
    Cancer chemotherapy reports, 1970, Volume: 54, Issue:4

    Topics: Antineoplastic Agents; Breast Neoplasms; Clinical Trials as Topic; Drug Combinations; Estradiol; Female; Humans; Hydroxyprogesterones; Lactones; Neoplasm Metastasis; Phenanthrenes; Testolactone

1970

Other Studies

30 other study(ies) available for testolactone and Breast Cancer

ArticleYear
A new hypothesis based on suicide substrate inhibitor studies for the mechanism of action of aromatase.
    Cancer research, 1982, Volume: 42, Issue:8 Suppl

    Topics: Androstadienes; Androstatrienes; Androstenedione; Androstenes; Aromatase Inhibitors; Breast Neoplasms; Estrogens; Female; Humans; Kinetics; Microsomes; Oxidoreductases; Placenta; Pregnancy; Structure-Activity Relationship; Testolactone

1982
[Behavior of serum lactic dehydrogenase (LDH) in disseminated breast cancer treated with delta-1-testololactone].
    Gazzetta internazionale di medicina e chirurgia, 1962, Dec-31, Volume: 66

    Topics: Antineoplastic Agents; Breast Neoplasms; Humans; L-Lactate Dehydrogenase; Lactones; Neoplasms; Testolactone

1962
[COMPARATIVE METHODICAL STUDY OF TESTOSTERONE PROPIONATE AND DELTA-1-TESTOLACTONE IN THE TREATMENT OF ADVANCED BREAST CANCER. PERSONAL EXPERIENCE WITHIN THE "EUROPEAN BREAST CANCER GROUP"].
    Bulletins et memoires de la Societe medicale des hopitaux de Paris, 1963, Jun-28, Volume: 114

    Topics: Antineoplastic Agents; Breast; Breast Neoplasms; Humans; Lactones; Neoplasms; Testolactone; Testosterone; Testosterone Propionate

1963
[THE HORMONAL TREATMENT OF ADVANCED BREAST CANCER. STUDY METHODS: COMPARISON OF DELTA-1-TESTOLOLACTONE WITH TESTOSTERONE PROPIONATE].
    Acta clinica Belgica, 1963, Volume: 18

    Topics: Antineoplastic Agents; Breast; Breast Neoplasms; Humans; Lactones; Neoplasms; Testolactone; Testosterone Propionate

1963
[HORMONE TREATMENT OF BREAST CANCER IN THE ADVANCED PHASE. COMPARISON BETWEEN TESTOSTERONE PROPIONATE AND THE TESTOSTERONE-DELTA-1-TESTOLOLACTONE COMBINATION].
    Revue francaise d'etudes cliniques et biologiques, 1964, Volume: 9

    Topics: Antineoplastic Agents; Breast Neoplasms; Humans; Lactones; Testolactone; Testosterone; Testosterone Propionate

1964
TREATMENT OF ADVANCED BREAST CARCINOMA WITH DELTA 1-TESTOLOLACTONE.
    Acta - Unio Internationalis Contra Cancrum, 1964, Volume: 20

    Topics: Abdominal Neoplasms; Antineoplastic Agents; Bone Neoplasms; Breast Neoplasms; Humans; Neoplasm Metastasis; Neoplasms; Testolactone

1964
High-dosage delta-1-testololactone therapy of disseminated carcinoma of the breast.
    Cancer, 1967, Volume: 20, Issue:3

    Topics: Aged; Antineoplastic Agents; Breast Neoplasms; Calcium; Carcinoma; Cholesterol; Female; Humans; Lipoproteins; Middle Aged; Neoplasm Metastasis; Phospholipids; Testolactone

1967
[Chemical adrenalectomy--a new alternative in the treatment of advanced breast cancer].
    Lakartidningen, 1983, Jun-29, Volume: 80, Issue:26-27

    Topics: Adrenal Glands; Aminoglutethimide; Breast Neoplasms; Female; Humans; Testolactone; Testosterone Congeners

1983
Biological significance of aromatase activity in human breast tumors.
    The Journal of clinical endocrinology and metabolism, 1983, Volume: 57, Issue:6

    Topics: Aminoglutethimide; Androstenedione; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Estrone; Female; Humans; Oxidoreductases; Receptors, Estrogen; Receptors, Progesterone; Testolactone

1983
Musculo-aponeurotic fibromatosis treated by surgery and testolactone.
    Journal of the Royal Society of Medicine, 1982, Volume: 75, Issue:4

    Topics: Adult; Breast; Breast Neoplasms; Female; Fibroma; Humans; Testolactone

1982
Estrogen synthesis in human breast tumor and its inhibition by testololactone and bromoandrostenedione.
    Cancer research, 1982, Volume: 42, Issue:8 Suppl

    Topics: Adrenalectomy; Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Castration; Estrogens; Female; Humans; Kinetics; Neoplasm Recurrence, Local; Oxidoreductases; Receptors, Estrogen; Testolactone

1982
Comparative studies of aromatase inhibitors in cultured human breast cancer cells.
    Cancer research, 1982, Volume: 42, Issue:8 Suppl

    Topics: Aminoglutethimide; Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Cell Line; Dihydrotestosterone; Estradiol; Female; Humans; Oxidoreductases; Pargyline; Receptors, Estrogen; Receptors, Progesterone; Testolactone; Testosterone

1982
In vivo effects of delta 1-testololactone on peripheral aromatization.
    Cancer research, 1982, Volume: 42, Issue:8 Suppl

    Topics: Aged; Androstenedione; Aromatase; Breast Neoplasms; Dexamethasone; Dose-Response Relationship, Drug; Estradiol; Estrone; Female; Humans; Menopause; Middle Aged; Oxidoreductases; Testolactone; Testosterone

1982
Advanced breast cancer - additive hormonal therapy.
    Cancer, 1981, May-15, Volume: 47, Issue:10

    Topics: Adrenal Cortex Hormones; Androgens; Breast Neoplasms; Estrogens; Female; Hormones; Humans; Mastectomy; Neoplasm Recurrence, Local; Progestins; Prognosis; Testolactone

1981
Inhibition of estrogen synthesis in human breast tumors by testololactone and bromoandrostenedione.
    Steroids, 1980, Volume: 35, Issue:5

    Topics: Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Estradiol; Estrone; Female; Humans; Kinetics; Steroids, Heterocyclic; Testolactone

1980
[3H-thymidine incorporation under endocrine influence and hormone receptor content of human mammary carcinoma (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1980, Oct-10, Volume: 105, Issue:41

    Topics: Breast Neoplasms; Estradiol; Female; Humans; Medroxyprogesterone; Receptors, Estrogen; Receptors, Progesterone; Testolactone; Thymidine

1980
[Calusterone (7-beta, 17-alpha-dimethyltestosterone) in the palliative treatment of advanced breast cancer].
    Minerva medica, 1977, Oct-31, Volume: 68, Issue:52

    Topics: Adult; Aged; Breast Neoplasms; Drug Evaluation; Female; Humans; Methyltestosterone; Middle Aged; Palliative Care; Testolactone; Testosterone

1977
Inhibition of peripheral aromatization in postmenopausal women with breast cancer.
    Surgical forum, 1978, Volume: 29

    Topics: Androstenedione; Breast Neoplasms; Estrone; Female; Humans; Menopause; Radioimmunoassay; Testolactone

1978
Inhibition of peripheral aromatization of androstenedione to estrone in postmenopausal women with breast cancer using delta 1-testololactone.
    The Journal of clinical endocrinology and metabolism, 1979, Volume: 49, Issue:5

    Topics: Aged; Androstenedione; Breast Neoplasms; Estradiol; Estrone; Female; Humans; Mastectomy; Menopause; Middle Aged; Steroids, Heterocyclic; Testolactone

1979
[Which hormone therapy should be used in advanced breast carcinoma in males?].
    Deutsche medizinische Wochenschrift (1946), 1988, Sep-02, Volume: 113, Issue:35

    Topics: Adenocarcinoma; Aged; Aminoglutethimide; Axilla; Breast Neoplasms; Dexamethasone; Drug Evaluation; Humans; Lymphatic Metastasis; Male; Medroxyprogesterone; Medroxyprogesterone Acetate; Megestrol; Megestrol Acetate; Tamoxifen; Testolactone; Testosterone Congeners

1988
Palliative treatment of mammary cancer. Response of soft tissue, pleural and pulmonary disease.
    Archives of surgery (Chicago, Ill. : 1960), 1973, Volume: 107, Issue:1

    Topics: Adrenalectomy; Adult; Age Factors; Aged; Breast Neoplasms; Castration; Cyclophosphamide; Dexamethasone; Estrogens; Female; Fluorouracil; Humans; Lung Neoplasms; Lymphatic Metastasis; Middle Aged; Neoplasm Metastasis; Palliative Care; Pleural Neoplasms; Prednisone; Testolactone; Thoracic Neoplasms

1973
A dose response evaluation of delta-1-testololactone in advanced breast cancer.
    Cancer, 1974, Volume: 33, Issue:1

    Topics: Adult; Age Factors; Aged; Breast Neoplasms; Castration; Dose-Response Relationship, Drug; Evaluation Studies as Topic; Female; Follow-Up Studies; Humans; Middle Aged; Neoplasm Metastasis; Ovary; Palliative Care; Prospective Studies; Remission, Spontaneous; Testolactone

1974
Hormonal therapy of breast cancer.
    Cancer, 1972, Volume: 30, Issue:6

    Topics: Breast Neoplasms; Castration; Female; Humans; Hypercalcemia; Methane; Methyltestosterone; Prognosis; Testolactone; Testosterone

1972
Androgenic therapy for advanced breast cancer in women. A report of the cooperative breast cancer group.
    JAMA, 1973, Mar-12, Volume: 223, Issue:11

    Topics: Administration, Oral; Adult; Aged; Androstanes; Breast Neoplasms; Dose-Response Relationship, Drug; Evaluation Studies as Topic; Female; Humans; Ketosteroids; Liver; Middle Aged; Neoplasm Metastasis; Remission, Spontaneous; Testolactone; Time Factors

1973
Combined high-dose delta1-testololactone with low-dose 5-fluorouracil in the treatment of metastatic breast cancer.
    Oncology, 1973, Volume: 27, Issue:6

    Topics: Blood Cell Count; Blood Platelets; Breast Neoplasms; Drug Therapy, Combination; Evaluation Studies as Topic; Female; Fluorouracil; Hematopoietic System; Humans; Leukocyte Count; Middle Aged; Neoplasm Metastasis; Testolactone

1973
Calusterone for breast cancer.
    The Medical letter on drugs and therapeutics, 1973, Nov-09, Volume: 15, Issue:23

    Topics: Blood Platelets; Breast Neoplasms; Female; Humans; Menopause; Methane; Methyltestosterone; Remission, Spontaneous; Stimulation, Chemical; Testolactone

1973
Leucopoietic effect of calusterone (7 beta, 17 alpha-dimethyltestosterone) in women with advanced breast cancer.
    Scandinavian journal of haematology, 1973, Volume: 10, Issue:3

    Topics: Administration, Oral; Breast Neoplasms; Drug Therapy, Combination; Female; Fluorouracil; Humans; Injections, Intravenous; Leukocyte Count; Leukocytes; Leukopenia; Methane; Methyltestosterone; Neoplasm Metastasis; Stimulation, Chemical; Testolactone

1973
The platelet-stimulating effects of 7-beta, 17-alpha-dimethyltestosterone (calusterone).
    Blood, 1972, Volume: 40, Issue:5

    Topics: Adult; Aged; Blood Cell Count; Blood Platelets; Breast Neoplasms; Erythrocytes; Female; Hematocrit; Humans; Middle Aged; Testolactone; Testosterone

1972
[Hormone treatment of breast cancer in the advanced phase].
    Bruxelles medical, 1968, Volume: 48, Issue:10

    Topics: Antineoplastic Agents; Breast Neoplasms; Female; Fluoxymesterone; Gonadotropins; Humans; Lactones; Nandrolone; Phenanthrenes; Secosteroids; Testolactone; Testosterone

1968
The metabolism of 4-14C-delta-1-testololactone.
    Steroids, 1966, Volume: 7, Issue:4

    Topics: Aged; Antineoplastic Agents; Bone Neoplasms; Breast Neoplasms; Carbon Isotopes; Chromatography; Female; Humans; Radiometry; Testolactone

1966