terikalant has been researched along with Arrhythmias, Cardiac in 7 studies
*Arrhythmias, Cardiac: Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction. [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (57.14) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jia, L; Sun, H | 1 |
| Coker, SJ; Farkas, A | 1 |
| Chen, QW; Dong, DL; Du, ZM; Gong, DM; Xu, CQ; Yang, BF | 1 |
| Escande, D | 1 |
| Curtis, MJ; Rees, SA | 2 |
| Brugada, J; Cavero, I; Escande, D; Kirchhof, C; Mestre, M | 1 |
1 review(s) available for terikalant and Arrhythmias, Cardiac
| Article | Year |
|---|---|
RP 58866 and its active enantiomer RP 62719 (terikalant): blockers of the inward rectifier K+ current acting as pure class III antiarrhythmic agents.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzopyrans; Chromans; Chromones; Electrophysiology; Humans; Models, Cardiovascular; Piperidines; Potassium Channels | 1992 |
6 other study(ies) available for terikalant and Arrhythmias, Cardiac
| Article | Year |
|---|---|
Support vector machines classification of hERG liabilities based on atom types.
Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve | 2008 |
Limited induction of torsade de pointes by terikalant and erythromycin in an in vivo model.
Topics: Action Potentials; Adrenergic alpha-1 Receptor Agonists; Animals; Anti-Arrhythmia Agents; Anti-Bacterial Agents; Arrhythmias, Cardiac; Blood Gas Analysis; Blood Pressure; Body Temperature; Chromans; Electrocardiography; Erythromycin; Heart Rate; Male; Piperidines; Quaternary Ammonium Compounds; Rabbits; Torsades de Pointes | 2002 |
[Comparison of the anti-arrhythmic effects of matrine and berbamine with amiodarone and RP58866].
Topics: Aconitine; Alkaloids; Amiodarone; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzylisoquinolines; Chromans; Dogs; Female; Guinea Pigs; Male; Matrines; Piperidines; Potassium Channels; Quinolizines; Rabbits; Rats | 2004 |
Commentaries on the IK1 blockade controversy (March issue)
Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Chromans; Dogs; Guinea Pigs; Humans; Piperidines; Potassium Channels; Rabbits; Rats; Species Specificity | 1994 |
IK1 blockade is a potentially useful antiarrhythmic mechanism.
Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Chromans; Ion Channel Gating; Piperidines; Potassium Channels; Rats | 1994 |
Specific IK1 blockade: a new antiarrhythmic mechanism? Effect of RP58866 on ventricular arrhythmias in rat, rabbit, and primate.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Callithrix; Cardiac Pacing, Artificial; Chromans; Electrocardiography; Heart; Male; Myocardial Reperfusion Injury; Piperidines; Potassium Channels; Rabbits; Rats; Rats, Wistar; Tachycardia, Ventricular; Ventricular Fibrillation | 1993 |