terfenadine has been researched along with Sneezing in 13 studies
Terfenadine: A selective histamine H1-receptor antagonist devoid of central nervous system depressant activity. The drug was used for ALLERGY but withdrawn due to causing LONG QT SYNDROME.
Sneezing: The sudden, forceful, involuntary expulsion of air from the NOSE and MOUTH caused by irritation to the MUCOUS MEMBRANES of the upper RESPIRATORY TRACT.
| Excerpt | Relevance | Reference |
|---|---|---|
| " However from 22 to 24 h after the first dose cetirizine was significantly superior to fexofenadine for the major symptom complex score and for sneezing." | 5.09 | Controlled comparison of the efficacy and safety of cetirizine 10 mg o.d. and fexofenadine 120 mg o.d. in reducing symptoms of seasonal allergic rhinitis. ( Burtin, B; De Vos, C; Donnelly, F; Horak, F; Kavina, A; Stübner, P; Zieglmayer, R, 2001) |
| "A study of ninety-nine hay fever sufferers was conducted to compare the effect of treatment with flunisolide nasal spray plus terfenadine tablets with that of terfenadine alone." | 5.06 | Treatment of seasonal allergic rhinitis with flunisolide and terfenadine. ( Backhouse, CI; Finnamore, VP; Gosden, CW, 1986) |
| " and intracerebroventricular pentobarbital-induced sedation and alcohol-induced ataxia models." | 3.76 | Characterization of anti-inflammatory properties and evidence for no sedation liability for the novel antihistamine SUN-1334H. ( Bagad, AS; Bahekar, PC; Chidrewar, GU; Mandhane, SN; Mehetre, SV; Pawar, CA; Rajamannar, T; Rao, CT; Shah, JH, 2010) |
| "We investigated the effects of the thromboxane (TX) A2 antagonist seratrodast, the peptide leukotriene (p-LT) antagonist pranlukast, the antihistaminic drug terfenadine and the glucocorticoid dexamethasone on antigen-induced sneezing, biphasic nasal blockage and nasal hyperresponsiveness to histamine using a guinea pig model of allergic rhinitis." | 3.71 | Involvement of thromboxane A2 and peptide leukotrienes in early and late phase nasal blockage in a guinea pig model of allergic rhinitis. ( Ashida, Y; Kohno, S; Matsumoto, T; Mizutani, N; Nabe, T; Sasaki, K; Yamasaki, M, 2001) |
| "Japanese cedar pollinosis, a common disease with morbidity of approximately 20% in the Japanese population, is characterized by subjectively irritating symptoms during an annual 3-month period." | 2.71 | The efficacy of short-term administration of 3 antihistamines vs placebo under natural exposure to Japanese cedar pollen. ( Fujieda, S; Hyo, S; Kawada, R; Kitazawa, S; Takenaka, H, 2005) |
| "Treatment with fexofenadine resulted in inhibition of allergen-induced symptoms and increased vascular permeability, but not the release of histamine and tryptase." | 2.70 | Effects of fexofenadine on the early response to nasal allergen challenge. ( Allocco, FT; Baroody, FM; deTineo, M; Naclerio, RM; Votypka, V, 2002) |
| "of terfenadine or placebo was made on the response to histamine and grass pollen skin-prick testing." | 2.67 | Comparison of a new antihistaminic and antiallergic compound KW 4679 with terfenadine and placebo on skin and nasal provocation in atopic individuals. ( Davies, RJ; Duddle, J; Hamilton, SA; Herdman, MJ; Trigg, CJ, 1994) |
| "The flurbiprofen-treated patients experienced less severe symptoms, demonstrating maximum benefit 3 to 5 days into the drug trial with some loss of effect thereafter." | 2.66 | Hay fever treatment with combined antihistamine and cyclooxygenase-inhibiting drugs. ( Brooks, CD; Karl, KJ, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (15.38) | 18.7374 |
| 1990's | 4 (30.77) | 18.2507 |
| 2000's | 6 (46.15) | 29.6817 |
| 2010's | 1 (7.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Enomoto, T | 1 |
| Lu, HQ | 1 |
| Yin, M | 1 |
| Sakoda, T | 1 |
| Dake, Y | 1 |
| Enomoto, K | 1 |
| Ide, T | 1 |
| Cheng, L | 1 |
| Mandhane, SN | 1 |
| Shah, JH | 1 |
| Bahekar, PC | 1 |
| Mehetre, SV | 1 |
| Pawar, CA | 1 |
| Bagad, AS | 1 |
| Chidrewar, GU | 1 |
| Rao, CT | 1 |
| Rajamannar, T | 1 |
| Allocco, FT | 1 |
| Votypka, V | 1 |
| deTineo, M | 1 |
| Naclerio, RM | 3 |
| Baroody, FM | 2 |
| Hyo, S | 1 |
| Fujieda, S | 1 |
| Kawada, R | 1 |
| Kitazawa, S | 1 |
| Takenaka, H | 1 |
| Wagenmann, M | 1 |
| Kagey-Sobotka, A | 1 |
| Lichtenstein, LM | 1 |
| Hamilton, SA | 1 |
| Duddle, J | 1 |
| Herdman, MJ | 1 |
| Trigg, CJ | 1 |
| Davies, RJ | 1 |
| Day, JH | 1 |
| Briscoe, MP | 1 |
| Clark, RH | 1 |
| Ellis, AK | 1 |
| Gervais, P | 1 |
| Horak, F | 1 |
| Stübner, P | 1 |
| Zieglmayer, R | 1 |
| Kavina, A | 1 |
| De Vos, C | 1 |
| Burtin, B | 1 |
| Donnelly, F | 1 |
| Yamasaki, M | 1 |
| Mizutani, N | 1 |
| Sasaki, K | 1 |
| Nabe, T | 1 |
| Matsumoto, T | 1 |
| Ashida, Y | 1 |
| Kohno, S | 1 |
| Ciprandi, G | 1 |
| Cosentino, C | 1 |
| Milanese, M | 1 |
| Mondino, C | 1 |
| Canonica, GW | 1 |
| Brooks, CD | 1 |
| Karl, KJ | 1 |
| Backhouse, CI | 1 |
| Finnamore, VP | 1 |
| Gosden, CW | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Nasal Ocular Reflexes Contribute to Eye Symptoms in Patients With Allergic Rhinitis[NCT00117832] | 20 participants | Interventional | 2005-03-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
11 trials available for terfenadine and Sneezing
| Article | Year |
|---|---|
Evaluation of the efficacy and safety of olopatadine and fexofenadine compared with placebo in Japanese cedar pollinosis using an environmental exposure unit.
Topics: Adult; Allergens; Cryptomeria; Dibenzoxepins; Double-Blind Method; Female; Follow-Up Studies; Histam | 2009 |
Effects of fexofenadine on the early response to nasal allergen challenge.
Topics: Adolescent; Adult; Allergens; Biomarkers; Capillary Permeability; Cross-Over Studies; Double-Blind M | 2002 |
The efficacy of short-term administration of 3 antihistamines vs placebo under natural exposure to Japanese cedar pollen.
Topics: Adult; Cetirizine; Cryptomeria; Double-Blind Method; Drug Administration Schedule; Female; Histamine | 2005 |
The effect of terfenadine on unilateral nasal challenge with allergen.
Topics: Adult; Airway Resistance; Allergens; Double-Blind Method; Female; Histamine Release; Humans; Hyperse | 1994 |
Comparison of a new antihistaminic and antiallergic compound KW 4679 with terfenadine and placebo on skin and nasal provocation in atopic individuals.
Topics: Adult; Airway Resistance; Cross-Over Studies; Dibenzoxepins; Double-Blind Method; Female; Humans; Ma | 1994 |
The effect of antihistamines on the immediate allergic response: a comparative review.
Topics: Capillary Permeability; Cetirizine; Cyproheptadine; Diphenhydramine; Double-Blind Method; Histamine | 1993 |
Onset of action and efficacy of terfenadine, astemizole, cetirizine, and loratadine for the relief of symptoms of allergic rhinitis.
Topics: Adolescent; Adult; Anti-Allergic Agents; Astemizole; Cetirizine; Double-Blind Method; Environmental | 1997 |
Controlled comparison of the efficacy and safety of cetirizine 10 mg o.d. and fexofenadine 120 mg o.d. in reducing symptoms of seasonal allergic rhinitis.
Topics: Adult; Anti-Allergic Agents; Bronchial Provocation Tests; Cetirizine; Cross-Over Studies; Double-Bli | 2001 |
Fexofenadine reduces nasal congestion in perennial allergic rhinitis.
Topics: Adolescent; Adult; Animals; Dose-Response Relationship, Drug; Double-Blind Method; Female; Histamine | 2001 |
Hay fever treatment with combined antihistamine and cyclooxygenase-inhibiting drugs.
Topics: Adult; Benzhydryl Compounds; Conjunctivitis; Cyclooxygenase Inhibitors; Drug Therapy, Combination; F | 1988 |
Treatment of seasonal allergic rhinitis with flunisolide and terfenadine.
Topics: Administration, Intranasal; Administration, Oral; Adolescent; Adult; Aged; Benzhydryl Compounds; Cli | 1986 |
2 other studies available for terfenadine and Sneezing
| Article | Year |
|---|---|
Characterization of anti-inflammatory properties and evidence for no sedation liability for the novel antihistamine SUN-1334H.
Topics: Acetates; Alcohols; Anaphylaxis; Animals; Anti-Inflammatory Agents, Non-Steroidal; Ataxia; Cetirizin | 2010 |
Involvement of thromboxane A2 and peptide leukotrienes in early and late phase nasal blockage in a guinea pig model of allergic rhinitis.
Topics: Animals; Anti-Allergic Agents; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Benzoquinones; Chrom | 2001 |