terfenadine has been researched along with Renal Insufficiency, Chronic in 2 studies
Terfenadine: A selective histamine H1-receptor antagonist devoid of central nervous system depressant activity. The drug was used for ALLERGY but withdrawn due to causing LONG QT SYNDROME.
Renal Insufficiency, Chronic: Conditions in which the KIDNEYS perform below the normal level for more than three months. Chronic kidney insufficiency is classified by five stages according to the decline in GLOMERULAR FILTRATION RATE and the degree of kidney damage (as measured by the level of PROTEINURIA). The most severe form is the end-stage renal disease (CHRONIC KIDNEY FAILURE). (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Midazolam AUC was significantly higher in the HD group (382." | 1.42 | Effect of CKD and dialysis modality on exposure to drugs cleared by nonrenal mechanisms. ( Asher, LJ; Feere, DA; House, AA; Knauer, MJ; Nolin, TD; Thomson, BK; Urquhart, BL; Velenosi, TJ, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Joy, MS | 1 |
| Frye, RF | 1 |
| Nolin, TD | 2 |
| Roberts, BV | 1 |
| La, MK | 1 |
| Wang, J | 1 |
| Brouwer, KL | 1 |
| Dooley, MA | 1 |
| Falk, RJ | 1 |
| Thomson, BK | 1 |
| Velenosi, TJ | 1 |
| Feere, DA | 1 |
| Knauer, MJ | 1 |
| Asher, LJ | 1 |
| House, AA | 1 |
| Urquhart, BL | 1 |
1 trial available for terfenadine and Renal Insufficiency, Chronic
| Article | Year |
|---|---|
In vivo alterations in drug metabolism and transport pathways in patients with chronic kidney diseases.
Topics: Adult; Aged; Aged, 80 and over; Biological Transport; Breath Tests; Case-Control Studies; Cytochrome | 2014 |
1 other study available for terfenadine and Renal Insufficiency, Chronic
| Article | Year |
|---|---|
Effect of CKD and dialysis modality on exposure to drugs cleared by nonrenal mechanisms.
Topics: Adult; Aged; Aged, 80 and over; Anti-Allergic Agents; Anti-Anxiety Agents; Cytochrome P-450 CYP3A; F | 2015 |