Page last updated: 2024-11-04

terfenadine and Muscle Contraction

terfenadine has been researched along with Muscle Contraction in 6 studies

Terfenadine: A selective histamine H1-receptor antagonist devoid of central nervous system depressant activity. The drug was used for ALLERGY but withdrawn due to causing LONG QT SYNDROME.

Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.

Research Excerpts

ExcerptRelevanceReference
" We examined the effectiveness of fexofenadine on isolated rat tracheal smooth muscle by testing the effect on: 1) tracheal smooth muscle resting tension; 2) contraction caused by 10E-6 M methacholine as a parasympathetic mimetic; and 3) electrically induced tracheal smooth muscle contractions."3.79Efficacy of fexofenadine in isolated rat tracheas. ( Chu, YH; Lai, WS; Lin, YY; Wang, CH; Wang, HW, 2013)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's3 (50.00)18.2507
2000's1 (16.67)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zhang, MQ2
Wada, Y2
Sato, F1
Timmerman, H2
Carceller, E1
Merlos, M1
Giral, M1
Balsa, D1
Almansa, C1
Bartrolí, J1
García-Rafanell, J1
Forn, J1
Menciu, C1
Duflos, M1
Fouchard, F1
Le Baut, G1
Emig, P1
Achterrath, U1
Szelenyi, I1
Nickel, B1
Schmidt, J1
Kutscher, B1
Günther, E1
Lai, WS1
Lin, YY1
Chu, YH1
Wang, CH1
Wang, HW1
Takizawa, T1
Matsumoto, J1
Tohma, T1
Kanke, T1
Nagao, M1
Inagaki, N1
Nagai, H1
Nolan, JC1
Stephens, DJ1
Proakis, AG1
Leonard, CA1
Johnson, DN1
Kilpatrick, BF1
Foxwell, MH1
Yanni, JM1

Other Studies

6 other studies available for terfenadine and Muscle Contraction

ArticleYear
(Piperidinylalkoxy)chromones: novel antihistamines with additional antagonistic activity against leukotriene D4.
    Journal of medicinal chemistry, 1995, Jun-23, Volume: 38, Issue:13

    Topics: Animals; Capillary Permeability; Cerebral Cortex; Chromones; Drug Antagonism; Guinea Pigs; Histamine

1995
[(3-Pyridylalkyl)piperidylidene]benzocycloheptapyridine derivatives as dual antagonists of PAF and histamine.
    Journal of medicinal chemistry, 1994, Aug-19, Volume: 37, Issue:17

    Topics: Anaphylaxis; Animals; Benzocycloheptenes; Blood Pressure; Guinea Pigs; Histamine; Histamine H1 Antag

1994
New N-(pyridin-4-yl)-(indol-3-yl)acetamides and propanamides as antiallergic agents.
    Journal of medicinal chemistry, 1999, Feb-25, Volume: 42, Issue:4

    Topics: Acetylcholine; Animals; Anti-Allergic Agents; Bronchoalveolar Lavage; Capillary Permeability; Carbac

1999
Efficacy of fexofenadine in isolated rat tracheas.
    Rhinology, 2013, Volume: 51, Issue:4

    Topics: Animals; Electric Stimulation; Histamine H1 Antagonists, Non-Sedating; Muscle Contraction; Muscle To

2013
VUF-K-8788, a periphery-selective histamine H1 antagonist with anti-pruritic activities.
    Japanese journal of pharmacology, 2001, Volume: 86, Issue:1

    Topics: Animals; Anti-Allergic Agents; Behavior, Animal; Benzimidazoles; Capillary Permeability; Guinea Pigs

2001
Rocastine (AHR-11325), a rapid acting, nonsedating antihistamine.
    Agents and actions, 1989, Volume: 28, Issue:1-2

    Topics: Anaphylaxis; Animals; Astemizole; Azepines; Benzhydryl Compounds; Benzimidazoles; Brompheniramine; C

1989