terfenadine has been researched along with Malignant Melanoma in 3 studies
Terfenadine: A selective histamine H1-receptor antagonist devoid of central nervous system depressant activity. The drug was used for ALLERGY but withdrawn due to causing LONG QT SYNDROME.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Previously we found that terfenadine, an H1 histamine receptor antagonist, acts as a potent apoptosis inducer in melanoma cells through modulation of Ca(2+) homeostasis." | 7.77 | Terfenadine induces apoptosis and autophagy in melanoma cells through ROS-dependent and -independent mechanisms. ( Alonso-Tejerina, E; Apraiz, A; Arroyo-Berdugo, Y; Asumendi, A; Boyano, MD; Careaga, JM; Díaz-Ramón, JL; Gardeazabal, J; Jangi, SM; Nicolau-Galmés, F; Pérez-Yarza, G, 2011) |
| "In our previous works, we have demonstrated that terfenadine (TEF) induces DNA damage and apoptosis in human melanoma cell lines." | 7.74 | Terfenadine-induced apoptosis in human melanoma cells is mediated through Ca2+ homeostasis modulation and tyrosine kinase activity, independently of H1 histamine receptors. ( Andollo, N; Arroyo-Berdugo, Y; Boyano, MD; Díaz-Pérez, JL; Jangi, SM; Nicolau-Galmés, F; Ortega-Martínez, I; Ruiz-Larrea, MB, 2008) |
| "Previously we found that terfenadine, an H1 histamine receptor antagonist, acts as a potent apoptosis inducer in melanoma cells through modulation of Ca(2+) homeostasis." | 3.77 | Terfenadine induces apoptosis and autophagy in melanoma cells through ROS-dependent and -independent mechanisms. ( Alonso-Tejerina, E; Apraiz, A; Arroyo-Berdugo, Y; Asumendi, A; Boyano, MD; Careaga, JM; Díaz-Ramón, JL; Gardeazabal, J; Jangi, SM; Nicolau-Galmés, F; Pérez-Yarza, G, 2011) |
| "In our previous works, we have demonstrated that terfenadine (TEF) induces DNA damage and apoptosis in human melanoma cell lines." | 3.74 | Terfenadine-induced apoptosis in human melanoma cells is mediated through Ca2+ homeostasis modulation and tyrosine kinase activity, independently of H1 histamine receptors. ( Andollo, N; Arroyo-Berdugo, Y; Boyano, MD; Díaz-Pérez, JL; Jangi, SM; Nicolau-Galmés, F; Ortega-Martínez, I; Ruiz-Larrea, MB, 2008) |
| "Histamine has been demonstrated to be involved in cell proliferation, embryonic development, and tumour growth." | 2.46 | Histamine and histamine receptor antagonists in cancer biology. ( Alonso-Tejerina, E; Asumendi, A; Blaya, B; Boyano, MD; Burgos-Bretones, J; Jangi, SM; Nicolau-Galmés, F; Ortega-Martínez, I; Pérez-Yarza, G, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Blaya, B | 1 |
| Nicolau-Galmés, F | 3 |
| Jangi, SM | 3 |
| Ortega-Martínez, I | 2 |
| Alonso-Tejerina, E | 2 |
| Burgos-Bretones, J | 1 |
| Pérez-Yarza, G | 2 |
| Asumendi, A | 2 |
| Boyano, MD | 3 |
| Gardeazabal, J | 1 |
| Arroyo-Berdugo, Y | 2 |
| Careaga, JM | 1 |
| Díaz-Ramón, JL | 1 |
| Apraiz, A | 1 |
| Ruiz-Larrea, MB | 1 |
| Andollo, N | 1 |
| Díaz-Pérez, JL | 1 |
1 review available for terfenadine and Malignant Melanoma
| Article | Year |
|---|---|
Histamine and histamine receptor antagonists in cancer biology.
Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Histamine; Histamine Antagonists; Histamin | 2010 |
2 other studies available for terfenadine and Malignant Melanoma
| Article | Year |
|---|---|
Terfenadine induces apoptosis and autophagy in melanoma cells through ROS-dependent and -independent mechanisms.
Topics: Apoptosis; Autophagy; Caspases; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Humans; Me | 2011 |
Terfenadine-induced apoptosis in human melanoma cells is mediated through Ca2+ homeostasis modulation and tyrosine kinase activity, independently of H1 histamine receptors.
Topics: Apoptosis; Base Sequence; Calcium; Cell Line, Tumor; Cyclic AMP; Cyclic GMP; DNA Primers; Egtazic Ac | 2008 |