terfenadine has been researched along with Liver Cirrhosis in 2 studies
Terfenadine: A selective histamine H1-receptor antagonist devoid of central nervous system depressant activity. The drug was used for ALLERGY but withdrawn due to causing LONG QT SYNDROME.
Liver Cirrhosis: Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 65-year-old woman with liver cirrhosis complicated by hepatocellular carcinoma lost consciousness due to torsades de pointes with prolongation of the QT-interval after 10 days of treatment with terfenadine." | 7.69 | Torsades de pointes associated with terfenadine in a case of liver cirrhosis and hepatocellular carcinoma. ( Adachi, Y; Kamisako, T; Nakagawa, H; Yamamoto, T, 1995) |
| "A 65-year-old woman with liver cirrhosis complicated by hepatocellular carcinoma lost consciousness due to torsades de pointes with prolongation of the QT-interval after 10 days of treatment with terfenadine." | 3.69 | Torsades de pointes associated with terfenadine in a case of liver cirrhosis and hepatocellular carcinoma. ( Adachi, Y; Kamisako, T; Nakagawa, H; Yamamoto, T, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kamisako, T | 1 |
| Adachi, Y | 1 |
| Nakagawa, H | 1 |
| Yamamoto, T | 1 |
| Venturini, E | 1 |
| Borghi, E | 1 |
| Maurini, V | 1 |
| Vecce, R | 1 |
| Carnicelli, A | 1 |
2 other studies available for terfenadine and Liver Cirrhosis
| Article | Year |
|---|---|
Torsades de pointes associated with terfenadine in a case of liver cirrhosis and hepatocellular carcinoma.
Topics: Aged; Carcinoma, Hepatocellular; Electrocardiography; Female; Humans; Liver Cirrhosis; Liver Neoplas | 1995 |
[Prolongation of the Q-T interval and hyperkinetic ventricular arrhythmias probably induced by terfenadine use in liver cirrhosis patients].
Topics: Arrhythmias, Cardiac; Electrocardiography; Female; Heart Ventricles; Humans; Liver Cirrhosis; Middle | 1992 |