terfenadine has been researched along with Inflammation in 6 studies
Terfenadine: A selective histamine H1-receptor antagonist devoid of central nervous system depressant activity. The drug was used for ALLERGY but withdrawn due to causing LONG QT SYNDROME.
Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fourteen atopic patients with mild-to-moderate asthma (forced expiratory volume in 1 second of 76%) completed a double-blind, randomized, crossover study consisting of 3-week treatment blocks of either fluticasone propionate-salmeterol, 250 microg twice daily, or fluticasone propionate alone, 250 microg twice daily, in conjunction with either fexofenadine, 180 mg once daily, or matched placebo." | 9.11 | Addition of fexofenadine to inhaled corticosteroid therapy to reduce inflammatory biomarkers in atopic asthma. ( Fardon, TC; Hodge, MR; Lee, DK; Lipworth, BJ, 2005) |
| "Fexofenadine treatment of sensitized mice prevented the development of airway hyperresponsiveness in both the primary sensitization and challenge, as well as in the adoptive transfer experiments." | 5.31 | Fexofenadine modulates T-cell function, preventing allergen-induced airway inflammation and hyperresponsiveness. ( Cui, ZH; Gelfand, EW; Joetham, A; Kanehiro, A; Takeda, K, 2002) |
| "Fourteen atopic patients with mild-to-moderate asthma (forced expiratory volume in 1 second of 76%) completed a double-blind, randomized, crossover study consisting of 3-week treatment blocks of either fluticasone propionate-salmeterol, 250 microg twice daily, or fluticasone propionate alone, 250 microg twice daily, in conjunction with either fexofenadine, 180 mg once daily, or matched placebo." | 5.11 | Addition of fexofenadine to inhaled corticosteroid therapy to reduce inflammatory biomarkers in atopic asthma. ( Fardon, TC; Hodge, MR; Lee, DK; Lipworth, BJ, 2005) |
| "Local inflammation is a prominent characteristic of snakebite wound, and snake-venom phospholipase A2s (PLA2s) are some of the main component that contribute to accumulation of inflammatory cells." | 1.39 | Induction of mast-cell accumulation by promutoxin, an Arg-49 phospholipase A2. ( He, S; Mo, YZ; Wei, JF; Wei, XL; Yang, H, 2013) |
| "Fexofenadine is a substrate of these transporters and it was previously shown that its clearance is reduced in the rat isolated perfused liver following treatment with E." | 1.36 | Pharmacokinetics of fexofenadine following LPS administration to rats. ( Davey, AK; Gerber, JP; Jaisue, S, 2010) |
| "Fexofenadine treatment of sensitized mice prevented the development of airway hyperresponsiveness in both the primary sensitization and challenge, as well as in the adoptive transfer experiments." | 1.31 | Fexofenadine modulates T-cell function, preventing allergen-induced airway inflammation and hyperresponsiveness. ( Cui, ZH; Gelfand, EW; Joetham, A; Kanehiro, A; Takeda, K, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Saunders, MJ | 1 |
| Edwards, BS | 1 |
| Zhu, J | 1 |
| Sklar, LA | 1 |
| Graves, SW | 1 |
| Wei, JF | 1 |
| Wei, XL | 1 |
| Mo, YZ | 1 |
| Yang, H | 1 |
| He, S | 1 |
| Jaisue, S | 1 |
| Gerber, JP | 1 |
| Davey, AK | 1 |
| Gelfand, EW | 1 |
| Cui, ZH | 1 |
| Takeda, K | 1 |
| Kanehiro, A | 1 |
| Joetham, A | 1 |
| Fardon, TC | 1 |
| Lee, DK | 1 |
| Hodge, MR | 1 |
| Lipworth, BJ | 1 |
| Kawada, N | 1 |
| Tanaka, H | 1 |
| Takizawa, T | 1 |
| Yamada, T | 1 |
| Takahashi, Y | 1 |
| Masuda, T | 1 |
| Inagaki, N | 1 |
| Nagai, H | 1 |
1 trial available for terfenadine and Inflammation
| Article | Year |
|---|---|
Addition of fexofenadine to inhaled corticosteroid therapy to reduce inflammatory biomarkers in atopic asthma.
Topics: Adenosine Monophosphate; Administration, Inhalation; Adolescent; Adrenal Cortex Hormones; Adult; Alb | 2005 |
5 other studies available for terfenadine and Inflammation
| Article | Year |
|---|---|
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr | 2010 |
Induction of mast-cell accumulation by promutoxin, an Arg-49 phospholipase A2.
Topics: Animals; Bothrops; Cell Adhesion Molecules; Cyproheptadine; Ginkgolides; Histamine; Histamine Releas | 2013 |
Pharmacokinetics of fexofenadine following LPS administration to rats.
Topics: Administration, Oral; Animals; Anti-Allergic Agents; Biological Availability; Inflammation; Injectio | 2010 |
Fexofenadine modulates T-cell function, preventing allergen-induced airway inflammation and hyperresponsiveness.
Topics: Adoptive Transfer; Allergens; Animals; Anti-Allergic Agents; Bronchial Hyperreactivity; Bronchoalveo | 2002 |
Role of mast cells in antigen-induced airway inflammation and bronchial hyperresponsiveness in rats.
Topics: Acetylcholine; Animals; Anti-Inflammatory Agents; Bronchial Hyperreactivity; Bronchoalveolar Lavage | 2001 |