terfenadine has been researched along with Hypotension in 3 studies
Terfenadine: A selective histamine H1-receptor antagonist devoid of central nervous system depressant activity. The drug was used for ALLERGY but withdrawn due to causing LONG QT SYNDROME.
Hypotension: Abnormally low BLOOD PRESSURE that can result in inadequate blood flow to the brain and other vital organs. Common symptom is DIZZINESS but greater negative impacts on the body occur when there is prolonged depravation of oxygen and nutrients.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Morphine and tubocurarine may release histamine by direct mast cell degranulation which may result in systemic effects such as cutaneous flushing, local wheal and flare formation and hypotension." | 5.07 | The influence of the H1 and H2 receptor antagonists, terfenadine and ranitidine on the hypotensive and gastric pH effects of the histamine releasing drugs, morphine and tubocurarine. ( Galletly, DC; Robinson, BJ; Short, TG; Treuren, BC; Ure, RW, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| McCord, JL | 1 |
| Pellinger, TK | 1 |
| Lynn, BM | 1 |
| Halliwill, JR | 2 |
| Lockwood, JM | 1 |
| Wilkins, BW | 1 |
| Treuren, BC | 1 |
| Galletly, DC | 1 |
| Robinson, BJ | 1 |
| Short, TG | 1 |
| Ure, RW | 1 |
3 trials available for terfenadine and Hypotension
| Article | Year |
|---|---|
Potential benefit from an H1-receptor antagonist on postexercise syncope in the heat.
Topics: Adolescent; Adult; Exercise; Female; Histamine H1 Antagonists, Non-Sedating; Hot Temperature; Humans | 2008 |
H1 receptor-mediated vasodilatation contributes to postexercise hypotension.
Topics: Adult; Exercise; Female; Histamine H1 Antagonists; Humans; Hypotension; Male; Receptors, Histamine H | 2005 |
The influence of the H1 and H2 receptor antagonists, terfenadine and ranitidine on the hypotensive and gastric pH effects of the histamine releasing drugs, morphine and tubocurarine.
Topics: Double-Blind Method; Female; Gastric Acid; Humans; Hydrogen-Ion Concentration; Hypotension; Middle A | 1993 |