terfenadine has been researched along with Hyperventilation in 3 studies
Terfenadine: A selective histamine H1-receptor antagonist devoid of central nervous system depressant activity. The drug was used for ALLERGY but withdrawn due to causing LONG QT SYNDROME.
Hyperventilation: A pulmonary ventilation rate faster than is metabolically necessary for the exchange of gases. It is the result of an increased frequency of breathing, an increased tidal volume, or a combination of both. It causes an excess intake of oxygen and the blowing off of carbon dioxide.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We investigated the contribution of the mast cell products, histamine and prostaglandins, to the bronchoconstriction induced by isocapnic hyperventilation (ISH) using single doses of terfenadine, a specific histamine H1-receptor antagonist, and flurbiprofen, a potent cyclooxygenase inhibitor." | 9.07 | The relative contributions of histamine and prostanoids to bronchoconstriction provoked by isocapnic hyperventilation in asthma. ( Finnerty, JP; Harvey, A; Holgate, ST, 1992) |
| "The effect of terfenadine, a selective H1-receptor antagonist devoid of central nervous system side effects, was evaluated on hyperventilation-induced bronchospasm in 11 adult subjects with asthma in a double-blind, placebo-controlled, crossover study." | 9.06 | Attenuation of hyperventilation-induced bronchospasm by terfenadine: a new antihistamine. ( Badier, M; Beaumont, D; Orehek, J, 1988) |
| " We investigated the contribution of the mast cell products, histamine and prostaglandins, to the bronchoconstriction induced by isocapnic hyperventilation (ISH) using single doses of terfenadine, a specific histamine H1-receptor antagonist, and flurbiprofen, a potent cyclooxygenase inhibitor." | 5.07 | The relative contributions of histamine and prostanoids to bronchoconstriction provoked by isocapnic hyperventilation in asthma. ( Finnerty, JP; Harvey, A; Holgate, ST, 1992) |
| "The effect of terfenadine, a selective H1-receptor antagonist devoid of central nervous system side effects, was evaluated on hyperventilation-induced bronchospasm in 11 adult subjects with asthma in a double-blind, placebo-controlled, crossover study." | 5.06 | Attenuation of hyperventilation-induced bronchospasm by terfenadine: a new antihistamine. ( Badier, M; Beaumont, D; Orehek, J, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Finnerty, JP | 1 |
| Harvey, A | 1 |
| Holgate, ST | 1 |
| Badier, M | 1 |
| Beaumont, D | 1 |
| Orehek, J | 1 |
| Townley, RG | 1 |
| Hopp, RJ | 1 |
| Bewtra, AK | 1 |
| Nabe, M | 1 |
3 trials available for terfenadine and Hyperventilation
| Article | Year |
|---|---|
The relative contributions of histamine and prostanoids to bronchoconstriction provoked by isocapnic hyperventilation in asthma.
Topics: Adolescent; Adult; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Double-Blind Method; Fe | 1992 |
Attenuation of hyperventilation-induced bronchospasm by terfenadine: a new antihistamine.
Topics: Adolescent; Adult; Asthma, Exercise-Induced; Benzhydryl Compounds; Bronchial Spasm; Clinical Trials | 1988 |
Effect of terfenadine on pulmonary function, histamine release, and bronchial challenges with nebulized water and cold-air hyperventilation.
Topics: Adult; Anthropometry; Basophils; Benzhydryl Compounds; Cold Temperature; Female; Histamine H1 Antago | 1989 |