terfenadine has been researched along with Hypersensitivity in 48 studies
Terfenadine: A selective histamine H1-receptor antagonist devoid of central nervous system depressant activity. The drug was used for ALLERGY but withdrawn due to causing LONG QT SYNDROME.
Hypersensitivity: Altered reactivity to an antigen, which can result in pathologic reactions upon subsequent exposure to that particular antigen.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To study the effect of fexofenadine on extensive alopecia areata (AA), we evaluated retrospectively 121 patients with AA having alopecia in more than 50% of the scalp and followed them for at least 6 months." | 7.75 | Fexofenadine hydrochloride enhances the efficacy of contact immunotherapy for extensive alopecia areata: Retrospective analysis of 121 cases. ( Inui, S; Itami, S; Nakajima, T; Toda, N, 2009) |
| "High incidence of allergy in ASD patients may indicate immune dysregulation that could be of relevance to the pathophysiology, symptomatology or neuroimmunology of ASD." | 5.51 | A novel concept of immunological and allergy interactions in autism spectrum disorders: Molecular, anti-inflammatory effect of osthole. ( Chwała, B; Cieślińska, A; Fiedorowicz, E; Jarmołowska, B; Kordulewska, NK; Kostyra, E; Moszyńska, M, 2019) |
| " and intracerebroventricular pentobarbital-induced sedation and alcohol-induced ataxia models." | 3.76 | Characterization of anti-inflammatory properties and evidence for no sedation liability for the novel antihistamine SUN-1334H. ( Bagad, AS; Bahekar, PC; Chidrewar, GU; Mandhane, SN; Mehetre, SV; Pawar, CA; Rajamannar, T; Rao, CT; Shah, JH, 2010) |
| "To study the effect of fexofenadine on extensive alopecia areata (AA), we evaluated retrospectively 121 patients with AA having alopecia in more than 50% of the scalp and followed them for at least 6 months." | 3.75 | Fexofenadine hydrochloride enhances the efficacy of contact immunotherapy for extensive alopecia areata: Retrospective analysis of 121 cases. ( Inui, S; Itami, S; Nakajima, T; Toda, N, 2009) |
| "Terfenadine is an antihistamine recently approved for use in the U." | 3.75 | Terfenadine, a nonsedating antihistamine. ( Carter, CA; Hayes, JM; Rickman, LA; Skoutakis, VA; Wojciechowski, NJ, 1985) |
| "In vivo antihistaminic activity experiments consisted of measurement of: inhibition of increase in capillary permeability and reduction in microvascular extravasation and bronchospasm in rats and guinea pigs induced by histamine and other inflammatory mediators; and protection against lethality induced by histamine and other inflammatory mediators in rats." | 3.73 | In vivo pharmacological characterisation of bilastine, a potent and selective histamine H1 receptor antagonist. ( Berisa, A; Corcóstegui, R; Innerárity, A; Labeaga, L; Orjales, A, 2006) |
| " The present studies compared loratadine and terfenadine, another non-sedating antihistamine, for their ability to inhibit the bronchial response to histamine and other autacoids which have been implicated as contributing to the symptoms of an allergic reaction." | 3.67 | Antiallergic activity of loratadine, a non-sedating antihistamine. ( Chapman, RW; Gulbenkian, A; Kreutner, W; Siegel, MI, 1987) |
| "Fexofenadine is safe and efficacious at single doses of 60 mg and 120 mg." | 2.68 | Onset of action, efficacy, and safety of a single dose of fexofenadine hydrochloride for ragweed allergy using an environmental exposure unit. ( Briscoe, MP; Clark, A; Day, JH; Ellis, AK; Mason, J; Smith, JN; Welsh, A, 1997) |
| "Terfenadine was more effective than both loratadine (P less than ." | 2.67 | Suppression of epicutaneous reactivity by terfenadine and loratadine. ( Small, P, 1992) |
| "With cetirizine, there was also a reduction in the levels of LTC4 (not measured in terfenadine studies) but not in those of recovered histamine and prostaglandin D2." | 2.66 | The effects of H1 antihistamines on the early allergic response. ( Baroody, F; Freidhoff, L; Kagey-Sobotka, A; Lichtenstein, LM; Naclerio, RM; Norman, PS; Proud, D, 1989) |
| "Terfenadine was evaluated for the relief of symptoms in patients with allergic pollinosis on a double-blind basis." | 2.65 | Clinical investigation of terfenadine, a non-sedating antihistamine. ( Brandon, ML; Weiner, M, 1980) |
| "Fexofenadine is a nonsedating, long-acting antihistamine with highly selective H(1)-receptor antagonist activity and a particularly favorable safety profile." | 2.42 | Effects of fexofenadine and other antihistamines on components of the allergic response: adhesion molecules. ( Canonica, GW; Ciprandi, G; Cosentino, C; Passalacqua, G; Riccio, AM; Tosca, MA, 2003) |
| "High incidence of allergy in ASD patients may indicate immune dysregulation that could be of relevance to the pathophysiology, symptomatology or neuroimmunology of ASD." | 1.51 | A novel concept of immunological and allergy interactions in autism spectrum disorders: Molecular, anti-inflammatory effect of osthole. ( Chwała, B; Cieślińska, A; Fiedorowicz, E; Jarmołowska, B; Kordulewska, NK; Kostyra, E; Moszyńska, M, 2019) |
| "Fexofenadine (FXF) is a third-generation antihistamine drug and osthole is assumed as a natural antihistamine alternative." | 1.46 | Changes in gene expression induced by histamine, fexofenadine and osthole: Expression of histamine H ( Cieślińska, A; Fiedorowicz, E; Kordulewska, NK; Kostyra, E; Matysiewicz, M; Sienkiewicz-Szłapka, E, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (27.08) | 18.7374 |
| 1990's | 15 (31.25) | 18.2507 |
| 2000's | 14 (29.17) | 29.6817 |
| 2010's | 6 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Walsh, DA | 1 |
| Franzyshen, SK | 1 |
| Yanni, JM | 1 |
| Menciu, C | 1 |
| Duflos, M | 1 |
| Fouchard, F | 1 |
| Le Baut, G | 1 |
| Emig, P | 1 |
| Achterrath, U | 1 |
| Szelenyi, I | 1 |
| Nickel, B | 1 |
| Schmidt, J | 1 |
| Kutscher, B | 1 |
| Günther, E | 1 |
| Kordulewska, N | 1 |
| Cieślińska, A | 4 |
| Fiedorowicz, E | 4 |
| Jarmołowska, B | 3 |
| Kostyra, E | 4 |
| Kordulewska, NK | 3 |
| Chwała, B | 1 |
| Moszyńska, M | 1 |
| Matysiewicz, M | 1 |
| Sienkiewicz-Szłapka, E | 1 |
| Inui, S | 1 |
| Nakajima, T | 1 |
| Toda, N | 1 |
| Itami, S | 1 |
| Smith, SM | 1 |
| Gums, JG | 1 |
| Mandhane, SN | 1 |
| Shah, JH | 1 |
| Bahekar, PC | 1 |
| Mehetre, SV | 1 |
| Pawar, CA | 1 |
| Bagad, AS | 1 |
| Chidrewar, GU | 1 |
| Rao, CT | 1 |
| Rajamannar, T | 1 |
| Andoh, T | 2 |
| Zhang, Q | 1 |
| Yamamoto, T | 1 |
| Tayama, M | 1 |
| Hattori, M | 1 |
| Tanaka, K | 1 |
| Kuraishi, Y | 2 |
| Duchateau, J | 1 |
| Heenen, M | 1 |
| Sternon, J | 1 |
| Grzelewska-Rzymowska, I | 1 |
| Ciprandi, G | 2 |
| Tosca, MA | 2 |
| Cosentino, C | 1 |
| Riccio, AM | 1 |
| Passalacqua, G | 1 |
| Canonica, GW | 2 |
| Ruëff, F | 1 |
| Przybilla, B | 1 |
| Corcóstegui, R | 1 |
| Labeaga, L | 1 |
| Innerárity, A | 1 |
| Berisa, A | 1 |
| Orjales, A | 1 |
| Camelo-Nunes, IC | 1 |
| Ohtsuka, E | 1 |
| Nakano, T | 1 |
| Kawai, S | 1 |
| Nojima, H | 1 |
| Kamimura, K | 1 |
| Asano, K | 1 |
| Kanai, K | 1 |
| Furuta, A | 1 |
| Furuya, A | 1 |
| Suzaki, H | 1 |
| Hisamitsu, T | 1 |
| Brandon, ML | 2 |
| Weiner, M | 1 |
| Bazex, J | 1 |
| Sans, B | 1 |
| Rostin, M | 1 |
| Barlow, JL | 1 |
| Beitman, RE | 1 |
| Tsai, TH | 1 |
| Lockhart, JD | 1 |
| Maneksha, S | 1 |
| Yakuo, I | 1 |
| Ishii, K | 1 |
| Seto, Y | 1 |
| Imano, K | 1 |
| Takeyama, K | 1 |
| Nakamura, H | 1 |
| Karasawa, T | 1 |
| Wagenmann, M | 1 |
| Baroody, FM | 1 |
| Kagey-Sobotka, A | 2 |
| Lichtenstein, LM | 2 |
| Naclerio, RM | 2 |
| Rajna, P | 1 |
| Veres, J | 1 |
| Soto, J | 1 |
| Sacristan, JA | 1 |
| Alsar, MJ | 1 |
| Sainz, C | 1 |
| Sabbah, A | 1 |
| Merk, HF | 1 |
| Day, JH | 1 |
| Briscoe, MP | 1 |
| Welsh, A | 1 |
| Smith, JN | 1 |
| Clark, A | 1 |
| Ellis, AK | 1 |
| Mason, J | 1 |
| Goldhill, J | 1 |
| Pichat, P | 1 |
| Roome, N | 1 |
| Angel, I | 1 |
| Arbilla, S | 1 |
| Abdelaziz, MM | 1 |
| Khair, OA | 1 |
| Devalia, JL | 1 |
| Fridliand, DG | 1 |
| Gushchin, IS | 1 |
| Poroshina, IuA | 1 |
| Shul'zhenko, AE | 1 |
| Small, P | 1 |
| Iudice, A | 1 |
| Buscaglia, S | 1 |
| Fasce, L | 1 |
| Ryhal, BT | 1 |
| Fletcher, MP | 1 |
| Dini, S | 1 |
| Caselli, GF | 1 |
| Basilico, C | 1 |
| Lavezzo, A | 1 |
| Giani, R | 1 |
| Kreutner, W | 1 |
| Chapman, RW | 1 |
| Gulbenkian, A | 1 |
| Siegel, MI | 1 |
| Lantin, JP | 1 |
| Pécoud, A | 2 |
| Goetz, DW | 1 |
| Jacobson, JM | 1 |
| Murnane, JE | 1 |
| Reid, MJ | 1 |
| Repperger, DW | 1 |
| Goodyear, C | 1 |
| Martin, ME | 1 |
| Baroody, F | 1 |
| Proud, D | 1 |
| Freidhoff, L | 1 |
| Norman, PS | 1 |
| Carter, CA | 1 |
| Wojciechowski, NJ | 1 |
| Hayes, JM | 1 |
| Skoutakis, VA | 1 |
| Rickman, LA | 1 |
| Turner, P | 1 |
8 reviews available for terfenadine and Hypersensitivity
| Article | Year |
|---|---|
Fexofenadine: biochemical, pharmacokinetic and pharmacodynamic properties and its unique role in allergic disorders.
Topics: Animals; Anti-Allergic Agents; Clinical Trials as Topic; Humans; Hypersensitivity; Terfenadine | 2009 |
[H1 histamine antagonists].
Topics: Acetates; Anti-Allergic Agents; Cetirizine; Chemistry, Pharmaceutical; Histamine H1 Antagonists; Hum | 2003 |
[Clinical aspects of anti-inflammatory action of antihistamines].
Topics: Cetirizine; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Hypersensitivi | 2003 |
Effects of fexofenadine and other antihistamines on components of the allergic response: adhesion molecules.
Topics: Anti-Allergic Agents; Cell Adhesion Molecules; Histamine H1 Antagonists; Humans; Hypersensitivity; L | 2003 |
Venom immunotherapy: adverse reactions and treatment failure.
Topics: Histamine H1 Antagonists; Humans; Hypersensitivity; Immunotherapy; Risk Factors; Terfenadine; Treatm | 2004 |
New antihistamines: a critical view.
Topics: Anti-Allergic Agents; Blood-Brain Barrier; Central Nervous System Diseases; Cetirizine; Child; Cypro | 2006 |
The second-generation antihistamines. What makes them different?
Topics: Astemizole; Benzhydryl Compounds; Benzimidazoles; Blood-Brain Barrier; Brain; Cetirizine; Cyprohepta | 1991 |
Terfenadine, a nonsedating antihistamine.
Topics: Benzhydryl Compounds; Clinical Trials as Topic; Drug Interactions; Formularies as Topic; Histamine H | 1985 |
11 trials available for terfenadine and Hypersensitivity
| Article | Year |
|---|---|
Clinical investigation of terfenadine, a non-sedating antihistamine.
Topics: Benzhydryl Compounds; Chlorpheniramine; Clinical Trials as Topic; Double-Blind Method; Histamine H1 | 1980 |
Comparative study of terfenadine in allergic skin of patients in France.
Topics: Adolescent; Adult; Aged; Benzhydryl Compounds; Child; Clemastine; Dermatitis; Dermatitis, Contact; F | 1982 |
Terfenadine, safety and tolerance in controlled clinical trials.
Topics: Benzhydryl Compounds; Clinical Trials as Topic; Dermatitis; Double-Blind Method; Histamine H1 Antago | 1982 |
Children with allergies. Terfenadine suspension versus placebo.
Topics: Benzhydryl Compounds; Child; Child, Preschool; Clinical Trials as Topic; Double-Blind Method; Female | 1983 |
The effect of terfenadine on unilateral nasal challenge with allergen.
Topics: Adult; Airway Resistance; Allergens; Double-Blind Method; Female; Histamine Release; Humans; Hyperse | 1994 |
Assessing the sedative (adverse) effects of antiallergic drugs by quantitative electroencephalography: effects of setastine a non-sedating antihistaminic drug.
Topics: Adult; Azepines; Cross-Over Studies; Double-Blind Method; Electroencephalography; Ethylenediamines; | 1994 |
Onset of action, efficacy, and safety of a single dose of fexofenadine hydrochloride for ragweed allergy using an environmental exposure unit.
Topics: Adolescent; Adult; Aged; Child; Double-Blind Method; Environmental Exposure; Female; Histamine Antag | 1997 |
Suppression of epicutaneous reactivity by terfenadine and loratadine.
Topics: Cyproheptadine; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Hypersensitivity; Lor | 1992 |
Prolongation of simple and choice reaction times in a double-blind comparison of twice-daily hydroxyzine versus terfenadine.
Topics: Adult; Benzhydryl Compounds; Central Nervous System; Decision Making; Double-Blind Method; Female; H | 1989 |
The effects of H1 antihistamines on the early allergic response.
Topics: Benzhydryl Compounds; Calcium Channels; Cetirizine; Dopamine; Histamine H1 Antagonists; Humans; Hydr | 1989 |
Terfenadine, a nonsedating antihistamine.
Topics: Benzhydryl Compounds; Clinical Trials as Topic; Drug Interactions; Formularies as Topic; Histamine H | 1985 |
30 other studies available for terfenadine and Hypersensitivity
| Article | Year |
|---|---|
Synthesis and antiallergy activity of 4-(diarylhydroxymethyl)-1-[3-(aryloxy)propyl]piperidines and structurally related compounds.
Topics: Anaphylaxis; Animals; Benzhydryl Compounds; Chemical Phenomena; Chemistry; Drug Evaluation, Preclini | 1989 |
New N-(pyridin-4-yl)-(indol-3-yl)acetamides and propanamides as antiallergic agents.
Topics: Acetylcholine; Animals; Anti-Allergic Agents; Bronchoalveolar Lavage; Capillary Permeability; Carbac | 1999 |
Effect of the Fexofenadine on the expression of HRH-1 and HRH-4 receptor in Peripheral Blood Mononuclear Cell isolated from children with diagnosed allergy - in vitro study Short communication.
Topics: Anti-Allergic Agents; Cells, Cultured; Child; Child, Preschool; Female; Gene Expression Regulation; | 2019 |
A novel concept of immunological and allergy interactions in autism spectrum disorders: Molecular, anti-inflammatory effect of osthole.
Topics: Anti-Inflammatory Agents; Autism Spectrum Disorder; Child; Child, Preschool; Coumarins; Cyclooxygena | 2019 |
Cytokine production by PBMC and serum from allergic and non-allergic subjects following in vitro histamine stimulation to test fexofenadine and osthole anti-allergic properties.
Topics: Adult; Anti-Allergic Agents; Coumarins; Cytokines; Histamine; Humans; Hypersensitivity; Immunoglobul | 2016 |
Changes in gene expression induced by histamine, fexofenadine and osthole: Expression of histamine H
Topics: Adult; Case-Control Studies; Chemokine CCL5; Coumarins; Cyclooxygenase 2; Female; Gene Expression Re | 2017 |
Fexofenadine hydrochloride enhances the efficacy of contact immunotherapy for extensive alopecia areata: Retrospective analysis of 121 cases.
Topics: Adjuvants, Immunologic; Adolescent; Adult; Aged; Alopecia Areata; Child; Child, Preschool; Cyclobuta | 2009 |
Characterization of anti-inflammatory properties and evidence for no sedation liability for the novel antihistamine SUN-1334H.
Topics: Acetates; Alcohols; Anaphylaxis; Animals; Anti-Inflammatory Agents, Non-Steroidal; Ataxia; Cetirizin | 2010 |
Inhibitory effects of the methanol extract of Ganoderma lucidum on mosquito allergy-induced itch-associated responses in mice.
Topics: Animals; Antipruritics; Culicidae; Drugs, Chinese Herbal; Fruit; Histamine; Histamine H1 Antagonists | 2010 |
Take allergy drug and sniff flowers safely?
Topics: Advertising; Allergens; Anti-Allergic Agents; Ephedrine; Histamine H1 Antagonists; Humans; Hypersens | 2005 |
In vivo pharmacological characterisation of bilastine, a potent and selective histamine H1 receptor antagonist.
Topics: Animals; Benzimidazoles; Bradykinin; Bronchial Spasm; Capillary Permeability; Cetirizine; Dermatitis | 2006 |
Possible involvement of 5-lipoxygenase metabolite in itch-associated response of mosquito allergy in mice.
Topics: Animals; Arachidonate 5-Lipoxygenase; Betamethasone Valerate; Bridged Bicyclo Compounds, Heterocycli | 2007 |
Suppressive activity of fexofenadine hydrochloride on nitric oxide production in-vitro and in-vivo.
Topics: Administration, Oral; Animals; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; | 2007 |
[Pharmacological study of ebastine, a novel histamine H1-receptor antagonist].
Topics: Administration, Oral; Animals; Butyrophenones; Disease Models, Animal; Dose-Response Relationship, D | 1994 |
Terfenadine-induced tremor.
Topics: Adolescent; Adult; Female; Humans; Hypersensitivity; Male; Rhinitis; Terfenadine; Tremor | 1993 |
[Teldane update. Interview with Dr. Alfred Sabbah, chief of the immuno-allergology laboratory of the C.H.U. d'Angers. Interview by Dr. Pierre Ceddaha].
Topics: Adult; Arrhythmias, Cardiac; Child; Child, Preschool; Contraindications; Cytochrome P-450 Enzyme Inh | 1993 |
[Introduction of a new antihistamine generation].
Topics: Histamine Antagonists; Histamine H1 Antagonists; Humans; Hypersensitivity; Hypersensitivity, Immedia | 1997 |
[Drug side effects and their prevention].
Topics: Arrhythmias, Cardiac; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Ele | 1997 |
[Fexofenadine--progress in antihistamine therapy].
Topics: Histamine H1 Antagonists; Humans; Hypersensitivity; Hypersensitivity, Immediate; Terfenadine | 1997 |
Effect of mizolastine on visceral sensory afferent sensitivity and inflammation during experimental colitis.
Topics: Animals; Benzimidazoles; Colitis; Colon; Histamine H1 Antagonists; Hypersensitivity; In Vitro Techni | 1998 |
The potential of active metabolites of antihistamines in the management of allergic disease.
Topics: Anti-Inflammatory Agents; Butyrophenones; Cells, Cultured; Cetirizine; Chymases; Eosinophils; Granul | 2000 |
Newer antihistamines.
Topics: Administration, Oral; Anti-Allergic Agents; Cetirizine; Chlorpheniramine; Conscious Sedation; Diphen | 2001 |
[Comparative antihistamine and anti-allergic effects of various antihistamine preparations].
Topics: Adult; Anti-Allergic Agents; Butyrophenones; Cetirizine; Clemastine; Female; Histamine H1 Antagonist | 2002 |
Terfenadine in allergic chronic cough in children.
Topics: Asthma; Child; Chronic Disease; Cough; Female; Humans; Hypersensitivity; Male; Pilot Projects; Terfe | 1992 |
Antihistaminic/antiallergic activity of 2-dialkylaminoalkylthio(oxy)-1-substituted benzimidazoles: evaluation "in vitro" and "in vivo".
Topics: Animals; Benzhydryl Compounds; Benzimidazoles; Blood-Brain Barrier; Brain; Clemastine; Guinea Pigs; | 1990 |
Antiallergic activity of loratadine, a non-sedating antihistamine.
Topics: Animals; Benzhydryl Compounds; Bronchial Spasm; Calcium; Cyproheptadine; Guinea Pigs; Histamine Anta | 1987 |
[Optimal use of antihistaminics].
Topics: Astemizole; Asthma; Benzhydryl Compounds; Benzimidazoles; Female; Histamine H1 Antagonists; Humans; | 1989 |
Newer non-sedating antihistamines. Will they replace older agents?
Topics: Astemizole; Benzhydryl Compounds; Benzimidazoles; Histamine H1 Antagonists; Humans; Hypersensitivity | 1985 |
[A new generation of H1-receptor antagonist antihistaminics].
Topics: Astemizole; Benzhydryl Compounds; Benzimidazoles; Histamine H1 Antagonists; Hypersensitivity; Phenot | 1986 |
Terfenadine: an anti-allergic drug.
Topics: Benzhydryl Compounds; Child; Child, Preschool; Histamine H1 Antagonists; Humans; Hypersensitivity; T | 1987 |