terfenadine has been researched along with Fatigue Syndrome, Chronic in 2 studies
Terfenadine: A selective histamine H1-receptor antagonist devoid of central nervous system depressant activity. The drug was used for ALLERGY but withdrawn due to causing LONG QT SYNDROME.
Fatigue Syndrome, Chronic: A syndrome characterized by persistent or recurrent fatigue, diffuse musculoskeletal pain, sleep disturbances, and subjective cognitive impairment of 6 months duration or longer. Symptoms are not caused by ongoing exertion; are not relieved by rest; and result in a substantial reduction of previous levels of occupational, educational, social, or personal activities. Minor alterations of immune, neuroendocrine, and autonomic function may be associated with this syndrome. There is also considerable overlap between this condition and FIBROMYALGIA. (From Semin Neurol 1998;18(2):237-42; Ann Intern Med 1994 Dec 15;121(12): 953-9)
| Excerpt | Relevance | Reference |
|---|---|---|
| "There is no established treatment for chronic fatigue syndrome (CFS), an illness characterized by disabling fatigue exacerbated by physical activity." | 2.68 | Double-blind placebo-controlled study of the efficacy of oral terfenadine in the treatment of chronic fatigue syndrome. ( Lurie, N; Marshall, P; McNutt, BE; Peterson, PK; Pheley, A; Schenck, C; Steinberg, P, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Steinberg, P | 2 |
| McNutt, BE | 1 |
| Marshall, P | 1 |
| Schenck, C | 1 |
| Lurie, N | 1 |
| Pheley, A | 1 |
| Peterson, PK | 2 |
| Marshall, PS | 1 |
| Watson, D | 1 |
| Cornblatt, B | 1 |
| Callies, A | 1 |
| Schenck, CH | 1 |
2 trials available for terfenadine and Fatigue Syndrome, Chronic
| Article | Year |
|---|---|
Double-blind placebo-controlled study of the efficacy of oral terfenadine in the treatment of chronic fatigue syndrome.
Topics: Administration, Oral; Adult; Double-Blind Method; Fatigue Syndrome, Chronic; Female; Histamine H1 An | 1996 |
An assessment of cognitive function and mood in chronic fatigue syndrome.
Topics: Adult; Aged; Anti-Allergic Agents; Attention; Cognition Disorders; Depression; Double-Blind Method; | 1996 |