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terfenadine and Erythema

terfenadine has been researched along with Erythema in 10 studies

Terfenadine: A selective histamine H1-receptor antagonist devoid of central nervous system depressant activity. The drug was used for ALLERGY but withdrawn due to causing LONG QT SYNDROME.

Erythema: Redness of the skin produced by congestion of the capillaries. This condition may result from a variety of disease processes.

Research Excerpts

ExcerptRelevanceReference
"Terfenadine, given in sufficient dose to cause maximum H1 receptor blockade, had no effect on the intensity of UVB or UVC erythema measured with a reflectance instrument at 4, 8, and 24 h after irradiation."9.06A quantitative study of the effect of terfenadine on cutaneous erythema induced by UVB and UVC radiation. ( Diffey, BL; Farr, PM; Humphreys, F, 1986)
"Treatment with the H1 receptor antagonist terfenadine increased significantly the dose of radiation required for weal and flare formation in 5 patients with idiopathic solar urticaria."7.67Treatment of solar urticaria with terfenadine. ( Diffey, BL; Farr, PM, 1988)
" The areas of weal and flare induced by intracutaneous injections of histamine were measured using planimetry, weal thickness by A-scan pulsed ultrasound and erythema index by a device which measures the relative reflectance of red and green light."5.07Effects of cetirizine, loratadine and terfenadine on histamine weal and flare reactions. ( Hill, S; Lever, LR; Marks, R; Rosenberg, R; Thompson, D, 1992)
"Terfenadine, given in sufficient dose to cause maximum H1 receptor blockade, had no effect on the intensity of UVB or UVC erythema measured with a reflectance instrument at 4, 8, and 24 h after irradiation."5.06A quantitative study of the effect of terfenadine on cutaneous erythema induced by UVB and UVC radiation. ( Diffey, BL; Farr, PM; Humphreys, F, 1986)
"Treatment with the H1 receptor antagonist terfenadine increased significantly the dose of radiation required for weal and flare formation in 5 patients with idiopathic solar urticaria."3.67Treatment of solar urticaria with terfenadine. ( Diffey, BL; Farr, PM, 1988)
"Terfenadine is a safe non-sedative H1-receptor antagonist."2.67Dose-response relationship between objective measures of histamine-induced weals and dose of terfenadine. ( Lush, M; Marks, R; Newcombe, RG; Shall, L, 1991)
" Pretreatment with antihistamines diminishes the incidence of adverse reactions (AR) such as large local and mild systemic reactions but it is suggested that it may mask a development of serious allergic reactions."1.33[Safety of venom immunotherapy in patients pretreated with antihistamines--a retrospective study]. ( Bocheńska-Marciniak, M; Kuna, P; Kupczyk, M; Kupryś-Lipińska, I; Tworek, D, 2006)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19905 (50.00)18.7374
1990's4 (40.00)18.2507
2000's1 (10.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tworek, D1
Bocheńska-Marciniak, M1
Kupczyk, M1
Kupryś-Lipińska, I1
Kuna, P1
Miyauchi, H1
Horio, T1
Brockow, K1
Kiehn, M1
Riethmüller, C1
Vieluf, D1
Berger, J1
Ring, J1
Lever, LR1
Hill, S1
Marks, R2
Rosenberg, R1
Thompson, D1
Shall, L1
Newcombe, RG1
Lush, M1
Cox, NH1
Higgins, EM1
Forr, PM1
Fuller, RW1
Conradson, TB1
Dixon, CM1
Crossman, DC1
Barnes, PJ1
Diffey, BL2
Farr, PM2
Van Neste, D1
Rihoux, JP1
Humphreys, F1

Trials

5 trials available for terfenadine and Erythema

ArticleYear
Efficacy of antihistamine pretreatment in the prevention of adverse reactions to Hymenoptera immunotherapy: a prospective, randomized, placebo-controlled trial.
    The Journal of allergy and clinical immunology, 1997, Volume: 100, Issue:4

    Topics: Administration, Oral; Adolescent; Adult; Aged; Animals; Arthropod Venoms; Desensitization, Immunolog

1997
Effects of cetirizine, loratadine and terfenadine on histamine weal and flare reactions.
    Skin pharmacology : the official journal of the Skin Pharmacology Society, 1992, Volume: 5, Issue:1

    Topics: Administration, Oral; Adult; Cetirizine; Cyproheptadine; Double-Blind Method; Erythema; Female; Hist

1992
Dose-response relationship between objective measures of histamine-induced weals and dose of terfenadine.
    Acta dermato-venereologica, 1991, Volume: 71, Issue:3

    Topics: Adult; Benzhydryl Compounds; Blister; Dose-Response Relationship, Drug; Double-Blind Method; Erythem

1991
Inhibition of the cutaneous response to histamine by H1-blocking agents. Quantitative evaluation of microvascular changes in the skin after histamine challenge and a comparison of the effects of a single intake of cetirizine and terfenadine.
    Skin pharmacology : the official journal of the Skin Pharmacology Society, 1988, Volume: 1, Issue:3

    Topics: Adult; Benzhydryl Compounds; Cetirizine; Dermatitis; Double-Blind Method; Erythema; Female; Histamin

1988
A quantitative study of the effect of terfenadine on cutaneous erythema induced by UVB and UVC radiation.
    The Journal of investigative dermatology, 1986, Volume: 87, Issue:6

    Topics: Adult; Animals; Benzhydryl Compounds; Dose-Response Relationship, Radiation; Erythema; Female; Hista

1986

Other Studies

5 other studies available for terfenadine and Erythema

ArticleYear
[Safety of venom immunotherapy in patients pretreated with antihistamines--a retrospective study].
    Pneumonologia i alergologia polska, 2006, Volume: 74, Issue:2

    Topics: Adolescent; Adult; Aged; Anaphylaxis; Animals; Bee Venoms; Desensitization, Immunologic; Erythema; F

2006
Detection of action, inhibition and augmentation spectra in solar urticaria.
    Dermatology (Basel, Switzerland), 1995, Volume: 191, Issue:4

    Topics: Anaphylaxis; Anti-Allergic Agents; Betamethasone; Cyclizine; Erythema; Female; Glucocorticoids; Hist

1995
Terfenadine inhibits itch and wheal, but not abnormal erythema, in physical urticarias.
    Journal of the American Academy of Dermatology, 1989, Volume: 21, Issue:3 Pt 1

    Topics: Adult; Benzhydryl Compounds; Erythema; Female; Histamine H1 Antagonists; Humans; Middle Aged; Prurit

1989
Sensory neuropeptide effects in human skin.
    British journal of pharmacology, 1987, Volume: 92, Issue:4

    Topics: Adult; Aspirin; Benzhydryl Compounds; Dose-Response Relationship, Drug; Drug Interactions; Erythema;

1987
Treatment of solar urticaria with terfenadine.
    Photo-dermatology, 1988, Volume: 5, Issue:1

    Topics: Adult; Benzhydryl Compounds; Erythema; Female; Histamine H1 Antagonists; Humans; Male; Sunlight; Ter

1988