Page last updated: 2024-11-04

terfenadine and Drop Attack

terfenadine has been researched along with Drop Attack in 7 studies

Terfenadine: A selective histamine H1-receptor antagonist devoid of central nervous system depressant activity. The drug was used for ALLERGY but withdrawn due to causing LONG QT SYNDROME.

Research Excerpts

ExcerptRelevanceReference
"This study compared the occurrence of syncope, ventricular arrhythmias, and corrected QT interval (QTc) prolongation over a 2 1/2-year period in persons prescribed terfenadine versus other prescription antihistamines among 265,000 members of the Harvard Community Health Plan (HCHP), the largest staff-model health maintenance organization in New England."7.69Terfenadine-associated ventricular arrhythmias and QTc interval prolongation. A retrospective cohort comparison with other antihistamines among members of a health maintenance organization. ( Carlson, W; Choo, PW; Faich, GA; Greineder, D; Hanrahan, JP; Platt, R, 1995)
"A 36-year-old female was given terfenadine 120 mg/day for hay fever, and itraconazole 100 mg twice daily for mycosis."7.69[Syncopes during simultaneous use of terfenadine and itraconazole]. ( Froger, CL; Romkes, JH; Westerhof, PW; Wever, EF, 1997)
"This study compared the occurrence of syncope, ventricular arrhythmias, and corrected QT interval (QTc) prolongation over a 2 1/2-year period in persons prescribed terfenadine versus other prescription antihistamines among 265,000 members of the Harvard Community Health Plan (HCHP), the largest staff-model health maintenance organization in New England."3.69Terfenadine-associated ventricular arrhythmias and QTc interval prolongation. A retrospective cohort comparison with other antihistamines among members of a health maintenance organization. ( Carlson, W; Choo, PW; Faich, GA; Greineder, D; Hanrahan, JP; Platt, R, 1995)
"A 36-year-old female was given terfenadine 120 mg/day for hay fever, and itraconazole 100 mg twice daily for mycosis."3.69[Syncopes during simultaneous use of terfenadine and itraconazole]. ( Froger, CL; Romkes, JH; Westerhof, PW; Wever, EF, 1997)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (85.71)18.2507
2000's1 (14.29)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
McCord, JL1
Pellinger, TK1
Lynn, BM1
Halliwill, JR1
Hanrahan, JP1
Choo, PW1
Carlson, W1
Greineder, D1
Faich, GA1
Platt, R1
Crane, JK1
Shih, HT1
Romkes, JH1
Froger, CL1
Wever, EF1
Westerhof, PW1
de Wildt, SN1
van den Anker, JN1
Lekkerkerker, JF1
Broekmans, AW1
Pinto, YM1
van Gelder, IC1
Heeringa, M1
Crijns, HJ1

Trials

1 trial available for terfenadine and Drop Attack

ArticleYear
Potential benefit from an H1-receptor antagonist on postexercise syncope in the heat.
    Medicine and science in sports and exercise, 2008, Volume: 40, Issue:11

    Topics: Adolescent; Adult; Exercise; Female; Histamine H1 Antagonists, Non-Sedating; Hot Temperature; Humans

2008

Other Studies

6 other studies available for terfenadine and Drop Attack

ArticleYear
Terfenadine-associated ventricular arrhythmias and QTc interval prolongation. A retrospective cohort comparison with other antihistamines among members of a health maintenance organization.
    Annals of epidemiology, 1995, Volume: 5, Issue:3

    Topics: Administration, Oral; Adolescent; Adult; Aged; Arrhythmias, Cardiac; Boston; Cohort Studies; Death,

1995
Syncope and cardiac arrhythmia due to an interaction between itraconazole and terfenadine.
    The American journal of medicine, 1993, Volume: 95, Issue:4

    Topics: Bradycardia; Drug Interactions; Humans; Itraconazole; Male; Middle Aged; Syncope; Terfenadine

1993
[Syncopes during simultaneous use of terfenadine and itraconazole].
    Nederlands tijdschrift voor geneeskunde, 1997, May-10, Volume: 141, Issue:19

    Topics: Adult; Anti-Allergic Agents; Antifungal Agents; Cardiotonic Agents; Female; Humans; Isoproterenol; I

1997
[Syncopes with simultaneous use of terfenadine and itraconazole].
    Nederlands tijdschrift voor geneeskunde, 1997, Sep-06, Volume: 141, Issue:36

    Topics: Anti-Allergic Agents; Antifungal Agents; Drug Interactions; Humans; Itraconazole; Syncope; Terfenadi

1997
[Syncopes with simultaneous use of terfenadine and itraconazole. Drug Monitoring Board].
    Nederlands tijdschrift voor geneeskunde, 1997, Sep-06, Volume: 141, Issue:36

    Topics: Anti-Allergic Agents; Antifungal Agents; Drug Monitoring; Humans; Itraconazole; Syncope; Terfenadine

1997
QT lengthening and life-threatening arrhythmias associated with fexofenadine.
    Lancet (London, England), 1999, Mar-20, Volume: 353, Issue:9157

    Topics: Aged; Electrocardiography; Histamine H1 Antagonists; Humans; Long QT Syndrome; Male; Syncope; Tachyc

1999