terfenadine has been researched along with Diabetes Mellitus, Type 2 in 2 studies
Terfenadine: A selective histamine H1-receptor antagonist devoid of central nervous system depressant activity. The drug was used for ALLERGY but withdrawn due to causing LONG QT SYNDROME.
Diabetes Mellitus, Type 2: A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Alogliptin (ALG), an inhibitor of dipeptidylpeptidase-4, is used in the management of type 2 diabetes mellitus, and has a high absorption rate (>60-71%), despite its low lipophilicity (logP=-1." | 1.62 | Intestinal Absorption of Alogliptin Is Mediated by a Fruit-Juice-Sensitive Transporter. ( Abe, M; Ishii, M; Kikuchi, T; Morimoto, K; Ogihara, T; Oikawa, E; Sasaki, M; Tomita, M, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hansen, SV | 1 |
| Christiansen, E | 1 |
| Urban, C | 1 |
| Hudson, BD | 1 |
| Stocker, CJ | 1 |
| Due-Hansen, ME | 1 |
| Wargent, ET | 1 |
| Shimpukade, B | 1 |
| Almeida, R | 1 |
| Ejsing, CS | 1 |
| Cawthorne, MA | 1 |
| Kassack, MU | 1 |
| Milligan, G | 1 |
| Ulven, T | 1 |
| Morimoto, K | 1 |
| Sasaki, M | 1 |
| Oikawa, E | 1 |
| Abe, M | 1 |
| Kikuchi, T | 1 |
| Ishii, M | 1 |
| Ogihara, T | 1 |
| Tomita, M | 1 |
2 other studies available for terfenadine and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
Discovery of a Potent Free Fatty Acid 1 Receptor Agonist with Low Lipophilicity, Low Polar Surface Area, and Robust in Vivo Efficacy.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Type 2; Drug Discovery; Glucose Tolerance Test; Hypoglyce | 2016 |
Intestinal Absorption of Alogliptin Is Mediated by a Fruit-Juice-Sensitive Transporter.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Administration, Oral; Animals; Caco-2 Cells; Citru | 2021 |